#=GF ID Rad50_zn_hook
#=GF AC PF04423.9
#=GF DE Rad50 zinc hook motif
#=GF AU Bateman A
#=GF SE Bateman A
#=GF GA 22.20 22.20;
#=GF TC 22.20 22.20;
#=GF NC 22.10 22.10;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Motif
#=GF RN [1]
#=GF RM 12152085
#=GF RT The Rad50 zinc-hook is a structure joining Mre11 complexes in
#=GF RT DNA recombination and repair.
#=GF RA Hopfner KP, Craig L, Moncalian G, Zinkel RA, Usui T, Owen BA,
#=GF RA Karcher A, Henderson B, Bodmer JL, McMurray CT, Carney JP,
#=GF RA Petrini JH, Tainer JA;
#=GF RL Nature 2002;418:562-566.
#=GF RN [2]
#=GF RM 12151226
#=GF RT Tethering on the brink: the evolutionarily conserved Mre11-Rad50
#=GF RT complex.
#=GF RA Connelly JC, Leach DR;
#=GF RL Trends Biochem Sci 2002;27:410-418.
#=GF DR INTERPRO; IPR007517;
#=GF DR SCOP; 1l8d; fa;
#=GF CC The Mre11 complex (Mre11 Rad50 Nbs1) is central to chromosomal
#=GF CC maintenance and functions in homologous recombination, telomere
#=GF CC maintenance and sister chromatid association. The Rad50
#=GF CC coiled-coil region contains a dimer interface at the apex of the
#=GF CC coiled coils in which pairs of conserved Cys-X-X-Cys motifs form
#=GF CC interlocking hooks that bind one Zn ion. This alignment includes
#=GF CC the zinc hook motif and a short stretch of coiled-coil on either
#=GF CC side.
#=GF SQ 262
#=GS B4KS80_DROMO/668-720 AC B4KS80.1
#=GS G1RQJ8_NOMLE/662-717 AC G1RQJ8.1
#=GS Q6FNZ8_CANGA/659-713 AC Q6FNZ8.1
#=GS G3H2B1_CRIGR/1-56 AC G3H2B1.1
#=GS G8JMK8_ERECY/651-705 AC G8JMK8.1
#=GS E7EN38_HUMAN/597-652 AC E7EN38.1
#=GS Q28ZL9_DROPS/668-720 AC Q28ZL9.2
#=GS RAD50_ARCFU/415-468 AC O29230.1
#=GS H3F7F3_PRIPA/12-66 AC H3F7F3.1
#=GS H3ZM36_THELI/419-479 AC H3ZM36.1
#=GS H2C3I3_9CREN/400-452 AC H2C3I3.1
#=GS E9JDB3_SOLIN/670-717 AC E9JDB3.1
#=GS E7Q876_YEASB/631-685 AC E7Q876.1
#=GS Q5SV02_MOUSE/658-713 AC Q5SV02.1
#=GS RAD50_PYRKO/418-471 AC Q5JHN1.1
#=GS A0SQ61_9SACH/665-719 AC A0SQ61.1
#=GS RAD50_THEVO/434-486 AC P58302.1
#=GS B0XC38_CULQU/107-148 AC B0XC38.1
#=GS RAD50_SULAC/414-468 AC O33600.1
#=GS F1RJV2_PIG/658-713 AC F1RJV2.1
#=GS E0SP05_IGNAA/355-406 AC E0SP05.1
#=GS G1N9X5_MELGA/659-713 AC G1N9X5.2
#=GS D3ENY1_UCYNA/479-528 AC D3ENY1.1
#=GS Q6CUR2_KLULA/651-705 AC Q6CUR2.1
#=GS A6ZRJ3_YEAS7/665-719 AC A6ZRJ3.1
#=GS F7DGI4_MACMU/658-713 AC F7DGI4.1
#=GS Q8YQ48_NOSS1/476-528 AC Q8YQ48.1
#=GS G3V9X6_RAT/658-713 AC G3V9X6.1
#=GS B4I847_DROSE/668-720 AC B4I847.1
#=GS RAD50_MOUSE/658-713 AC P70388.1
#=GS RAD50_DROME/668-720 AC Q9W252.4
#=GS F4WFQ0_ACREC/667-710 AC F4WFQ0.1
#=GS G5J0N6_CROWT/101-152 AC G5J0N6.1
#=GS RAD50_CAEEL/645-698 AC O44199.1
#=GS G3QBX6_GASAC/659-714 AC G3QBX6.1
#=GS G2SF07_RHOMR/490-543 AC G2SF07.1
#=GS G1U4Q5_RABIT/656-711 AC G1U4Q5.1
#=GS H9YVE3_MACMU/658-713 AC H9YVE3.1
#=GS RAD50_HUMAN/658-713 AC Q92878.1
#=GS C5XSH1_SORBI/106-147 AC C5XSH1.1
#=GS F0QT70_VULM7/386-438 AC F0QT70.1
#=GS B4GHK9_DROPE/668-720 AC B4GHK9.1
#=GS D3ZPN8_RAT/597-652 AC D3ZPN8.1
#=GS F0LM45_THEBM/418-471 AC F0LM45.1
#=GS C7P7E8_METFA/481-534 AC C7P7E8.1
#=GS A4YET5_METS5/397-451 AC A4YET5.1
#=GS Q16FI3_AEDAE/409-461 AC Q16FI3.1
#=GS B9S9Y8_RICCO/677-726 AC B9S9Y8.1
#=GS E6UPU3_CLOTL/439-481 AC E6UPU3.1
#=GS G7MUA6_MACMU/635-690 AC G7MUA6.1
#=GS B4VXN7_9CYAN/477-527 AC B4VXN7.1
#=GS A5JYU5_CAEEL/659-712 AC A5JYU5.1
#=GS G0UC67_TRYVI/670-721 AC G0UC67.1
#=GS Q6L2H8_PICTO/420-469 AC Q6L2H8.1
#=GS G9KJY1_MUSPF/658-713 AC G9KJY1.1
#=GS B5FW66_OTOGA/658-713 AC B5FW66.1
#=GS RAD50_SCHPO/653-705 AC Q9UTJ8.3
#=GS RAD50_PYRFU/422-475 AC P58301.1
#=GS RAD50_PYRFU/422-475 DR PDB; 1L8D B; 422-475;
#=GS RAD50_PYRFU/422-475 DR PDB; 1L8D A; 422-475;
#=GS C7GPB1_YEAS2/665-719 AC C7GPB1.1
#=GS E8T6E8_THEA1/420-473 AC E8T6E8.1
#=GS D7LEB9_ARALL/647-695 AC D7LEB9.1
#=GS Q533U0_MUNMU/69-123 AC Q533U0.1
#=GS B3NNP5_DROER/668-720 AC B3NNP5.1
#=GS D3E346_METRM/461-514 AC D3E346.1
#=GS I1P0L1_ORYGL/677-726 AC I1P0L1.1
#=GS B7P1K3_IXOSC/622-668 AC B7P1K3.1
#=GS F0NFK6_SULIR/403-457 AC F0NFK6.1
#=GS F6SPI9_XENTR/661-716 AC F6SPI9.1
#=GS C5A1H5_THEGJ/416-468 AC C5A1H5.1
#=GS D0KUC4_SULS9/403-457 AC D0KUC4.1
#=GS B0JQH4_MICAN/479-529 AC B0JQH4.1
#=GS RAD50_METKA/410-465 AC Q8TXI4.1
#=GS C7SB53_PLADU/580-633 AC C7SB53.1
#=GS Q7RVZ9_NEUCR/669-723 AC Q7RVZ9.1
#=GS I0A1C6_9CREN/460-512 AC I0A1C6.1
#=GS B4MJF7_DROWI/669-721 AC B4MJF7.1
#=GS E7KHE0_YEASA/631-685 AC E7KHE0.1
#=GS RAD50_AERPE/440-495 AC Q9YFZ1.1
#=GS G3T4B6_LOXAF/658-713 AC G3T4B6.1
#=GS RAD50_RAT/658-713 AC Q9JIL8.1
#=GS H0UY19_CAVPO/662-717 AC H0UY19.1
#=GS C3N8B7_SULIY/403-457 AC C3N8B7.1
#=GS RAD50_METMP/475-526 AC P62134.1
#=GS E2A7J8_CAMFO/666-712 AC E2A7J8.1
#=GS B0WAP9_CULQU/668-720 AC B0WAP9.1
#=GS D1NIQ0_CLOTM/439-481 AC D1NIQ0.1
#=GS H0GM90_9SACH/631-685 AC H0GM90.1
#=GS D0MI39_RHOM4/490-543 AC D0MI39.1
#=GS C3N0D1_SULIA/403-457 AC C3N0D1.1
#=GS B2KIE7_RHIFE/658-713 AC B2KIE7.1
#=GS C9RHD0_METVM/477-530 AC C9RHD0.1
#=GS F0NMQ6_SULIH/403-457 AC F0NMQ6.1
#=GS H2PGI2_PONAB/658-713 AC H2PGI2.1
#=GS B4MFQ7_DROVI/669-721 AC B4MFQ7.1
#=GS Q6MGE2_NEUCS/669-723 AC Q6MGE2.1
#=GS D1C4W6_SPHTD/403-454 AC D1C4W6.1
#=GS B5IGG2_ACIB4/391-444 AC B5IGG2.1
#=GS B6JYL6_SCHJY/623-675 AC B6JYL6.1
#=GS F4B9U7_ACIHW/402-456 AC F4B9U7.1
#=GS F6RZ99_CIOIN/234-288 AC F6RZ99.2
#=GS G5ASP8_HETGA/687-742 AC G5ASP8.1
#=GS C6A1X5_THESM/362-414 AC C6A1X5.1
#=GS A9A9X2_METM6/475-527 AC A9A9X2.1
#=GS G0EHQ4_PYRF1/436-489 AC G0EHQ4.1
#=GS I1MYA5_SOYBN/678-724 AC I1MYA5.1
#=GS E0W0B2_PEDHC/660-713 AC E0W0B2.1
#=GS F6RT86_MONDO/658-713 AC F6RT86.1
#=GS D2A5X5_TRICA/668-718 AC D2A5X5.1
#=GS G3X6W2_BOVIN/658-713 AC G3X6W2.1
#=GS F8AI78_PYRYC/419-472 AC F8AI78.1
#=GS Q4RIQ9_TETNG/658-713 AC Q4RIQ9.1
#=GS RAD50_ARATH/677-726 AC Q9SL02.2
#=GS Q752D9_ASHGO/650-704 AC Q752D9.2
#=GS E2B8W9_HARSA/666-713 AC E2B8W9.1
#=GS A8YKL8_MICAE/481-531 AC A8YKL8.1
#=GS A8ACA9_IGNH4/415-467 AC A8ACA9.1
#=GS H1KYJ1_9EURY/472-525 AC H1KYJ1.1
#=GS E3LQ28_CAERE/659-712 AC E3LQ28.1
#=GS E3X070_ANODA/249-301 AC E3X070.1
#=GS I0I7E2_9CHLR/439-491 AC I0I7E2.1
#=GS H3JGN1_STRPU/743-797 AC H3JGN1.1
#=GS H8EBX3_CLOTM/439-481 AC H8EBX3.1
#=GS F6W0H6_XENTR/657-712 AC F6W0H6.1
#=GS G0V5A1_NAUCC/657-711 AC G0V5A1.1
#=GS F7AR56_HORSE/658-713 AC F7AR56.1
#=GS A0ZDB3_NODSP/476-527 AC A0ZDB3.1
#=GS Q7Y239_ORYSJ/677-725 AC Q7Y239.2
#=GS G8ZSI8_TORDC/658-712 AC G8ZSI8.1
#=GS C4N9Q9_XENLA/658-713 AC C4N9Q9.1
#=GS B9AD32_METSM/447-512 AC B9AD32.1
#=GS Q9C499_NEUCS/669-723 AC Q9C499.1
#=GS F1NEG1_CHICK/659-713 AC F1NEG1.1
#=GS C0QRS0_PERMH/437-488 AC C0QRS0.1
#=GS G8BQ10_TETPH/656-708 AC G8BQ10.1
#=GS RAD50_PYRHO/419-472 AC O58687.1
#=GS B5IAI0_ACIB4/391-444 AC B5IAI0.1
#=GS B9F043_ORYSJ/968-1015 AC B9F043.1
#=GS H3GXW6_PHYRM/387-436 AC H3GXW6.1
#=GS E7QJM6_YEASZ/665-719 AC E7QJM6.1
#=GS B7NZL1_RABIT/658-713 AC B7NZL1.1
#=GS F7EPF8_ORNAN/658-713 AC F7EPF8.1
#=GS E9QPC6_MOUSE/597-652 AC E9QPC6.1
#=GS D0Z764_DROME/672-724 AC D0Z764.1
#=GS F0TBV3_METSL/437-490 AC F0TBV3.1
#=GS D5U1T6_THEAM/462-516 AC D5U1T6.1
#=GS RAD50_THEAC/434-486 AC Q9HLR8.1
#=GS G2WLL6_YEASK/665-719 AC G2WLL6.1
#=GS C7DHY0_9EURY/369-419 AC C7DHY0.1
#=GS F6BLP7_THEXL/399-460 AC F6BLP7.1
#=GS G7JAR6_MEDTR/886-934 AC G7JAR6.1
#=GS A6UUX2_META3/475-529 AC A6UUX2.1
#=GS G0MP92_CAEBE/671-724 AC G0MP92.1
#=GS A8Y3Y7_CAEBR/702-755 AC A8Y3Y7.1
#=GS B8AIA2_ORYSI/677-726 AC B8AIA2.1
#=GS F8AKK1_METOI/479-532 AC F8AKK1.1
#=GS C8ZFY7_YEAS8/665-719 AC C8ZFY7.1
#=GS B9GFJ5_POPTR/677-726 AC B9GFJ5.1
#=GS A6VGS8_METM7/475-526 AC A6VGS8.1
#=GS RAD50_SULSO/403-457 AC Q97WH0.1
#=GS A3IMA1_9CHRO/122-172 AC A3IMA1.1
#=GS D7E132_NOSA0/478-525 AC D7E132.1
#=GS H2WAC9_CAEJA/447-500 AC H2WAC9.1
#=GS D2ZRK4_METSM/447-500 AC D2ZRK4.1
#=GS A3DDZ9_CLOTH/439-481 AC A3DDZ9.1
#=GS G4XIR2_9BRYO/675-725 AC G4XIR2.1
#=GS C4KJH9_SULIK/403-457 AC C4KJH9.1
#=GS A8MDQ4_CALMQ/387-441 AC A8MDQ4.1
#=GS RAD50_PYRAB/420-473 AC Q9UZC8.1
#=GS B1X172_CYAA5/478-528 AC B1X172.1
#=GS F6BAS4_METIK/472-525 AC F6BAS4.1
#=GS B3MEF0_DROAN/667-718 AC B3MEF0.1
#=GS B3LP94_YEAS1/665-719 AC B3LP94.1
#=GS F7VKE1_SORMK/670-724 AC F7VKE1.1
#=GS B4P7X9_DROYA/668-720 AC B4P7X9.1
#=GS H2S8G2_TAKRU/658-713 AC H2S8G2.1
#=GS E8MYK6_ANATU/403-454 AC E8MYK6.1
#=GS B7R252_9EURY/416-468 AC B7R252.1
#=GS B4J9P7_DROGR/662-714 AC B4J9P7.1
#=GS B3QT75_CHLT3/414-467 AC B3QT75.1
#=GS B1MTQ1_CALMO/658-713 AC B1MTQ1.1
#=GS B2J0P5_NOSP7/478-525 AC B2J0P5.1
#=GS F0LKK5_THEBM/428-480 AC F0LKK5.1
#=GS F4HJV8_PYRSN/419-472 AC F4HJV8.1
#=GS H3IRN8_STRPU/545-598 AC H3IRN8.1
#=GS C5DYV4_ZYGRC/657-711 AC C5DYV4.1
#=GS E7KTA1_YEASL/631-685 AC E7KTA1.1
#=GS C3MTS1_SULIM/403-457 AC C3MTS1.1
#=GS G4YI53_PHYSP/713-758 AC G4YI53.1
#=GS A5UJE7_METS3/447-512 AC A5UJE7.1
#=GS A7RWC7_NEMVE/211-266 AC A7RWC7.1
#=GS G1KMS1_ANOCA/659-714 AC G1KMS1.1
#=GS D7FB72_9HYME/91-142 AC D7FB72.1
#=GS D2GVH6_AILME/658-713 AC D2GVH6.1
#=GS H2QRG6_PANTR/658-713 AC H2QRG6.1
#=GS G0WD57_NAUDC/658-712 AC G0WD57.1
#=GS H3DLI5_TETNG/658-713 AC H3DLI5.1
#=GS C3PT86_DASNO/658-713 AC C3PT86.1
#=GS H9KYC4_CALJA/311-366 AC H9KYC4.1
#=GS A4FWH8_METM5/475-527 AC A4FWH8.1
#=GS A8UZN2_9AQUI/437-490 AC A8UZN2.1
#=GS Q7NCW4_GLOVI/469-529 AC Q7NCW4.1
#=GS RAD50_YEAST/665-719 AC P12753.1
#=GS G1PUW7_MYOLU/662-717 AC G1PUW7.1
#=GS G0H206_METMI/475-528 AC G0H206.1
#=GS E2QT24_CANFA/660-715 AC E2QT24.1
#=GS D2RFR1_ARCPA/414-466 AC D2RFR1.1
#=GS B6YXU9_THEON/418-471 AC B6YXU9.1
#=GS G8LZ19_CLOCD/436-482 AC G8LZ19.1
#=GS C1DVT9_SULAA/430-497 AC C1DVT9.1
#=GS I1CMI7_RHIO9/533-593 AC I1CMI7.1
#=GS G3QFG8_GORGO/658-713 AC G3QFG8.1
#=GS B0KWP2_CALJA/658-713 AC B0KWP2.1
#=GS H8EJU5_CLOTM/439-481 AC H8EJU5.1
#=GS G1MH82_AILME/658-713 AC G1MH82.1
#=GS Q32P42_HUMAN/658-713 AC Q32P42.1
#=GS G3WB07_SARHA/660-715 AC G3WB07.1
#=GS F0S398_DESTD/426-480 AC F0S398.1
#=GS B2G497_ZYGRO/657-711 AC B2G497.1
#=GS G6GWV6_9CHRO/478-528 AC G6GWV6.1
#=GS C5DKA6_LACTC/651-705 AC C5DKA6.1
#=GS Q8DGY7_THEEB/476-526 AC Q8DGY7.1
#=GS F1Q537_DANRE/658-713 AC F1Q537.1
#=GS G6FW84_9CYAN/479-529 AC G6FW84.1
#=GS B4QH58_DROSI/668-720 AC B4QH58.1
#=GS Q5W4T6_CHICK/659-713 AC Q5W4T6.1
#=GS B5VQF9_YEAS6/665-719 AC B5VQF9.1
#=GS D9Q224_ACIS3/450-504 AC D9Q224.1
#=GS H0YT14_TAEGU/659-713 AC H0YT14.1
#=GS D2PDY1_SULID/403-457 AC D2PDY1.1
#=GS RAD50_SULTO/417-471 AC Q96YR5.2
#=GS A2BM16_HYPBU/437-490 AC A2BM16.1
#=GS D0MSB2_PHYIT/682-730 AC D0MSB2.1
#=GS F6VU98_XENTR/658-713 AC F6VU98.1
#=GS C3MJD9_SULIL/403-457 AC C3MJD9.1
#=GS G6DRY5_DANPL/622-668 AC G6DRY5.1
#=GS D3ZBK7_RAT/658-713 AC D3ZBK7.1
#=GS F4G3H5_METCR/399-448 AC F4G3H5.1
#=GS G0HJU4_THES4/418-469 AC G0HJU4.1
#=GS RAD50_METJA/480-533 AC Q58718.1
#=GS A0SQ62_SACPS/665-719 AC A0SQ62.1
#=GS Q7QAJ3_ANOGA/669-721 AC Q7QAJ3.4
#=GS G7P885_MACFA/658-713 AC G7P885.1
#=GS D3S7S2_METSF/481-534 AC D3S7S2.1
#=GS A9CB11_PAPAN/658-713 AC A9CB11.1
#=GS A8Y5I3_MOUSE/597-652 AC A8Y5I3.1
#=GS H9HGI0_ATTCE/666-712 AC H9HGI0.1
#=GS H2AUH4_KAZAF/656-710 AC H2AUH4.1
#=GS C7HHM4_CLOTM/439-481 AC C7HHM4.1
#=GS H3A560_LATCH/537-592 AC H3A560.1
#=GS B0W2Q1_CULQU/75-116 AC B0W2Q1.1
#=GS Q5XH50_XENLA/658-713 AC Q5XH50.1
#=GS H0H044_9SACH/635-689 AC H0H044.1
#=GS F6D565_METSW/436-488 AC F6D565.1
#=GS D5VSC5_METIM/411-464 AC D5VSC5.1
#=GS Q17AN3_AEDAE/392-444 AC Q17AN3.1
#=GS A5AV28_VITVI/23-72 AC A5AV28.1
#=GS A7TF44_VANPO/658-712 AC A7TF44.1
#=GS H2L8A9_ORYLA/658-713 AC H2L8A9.1
#=GS F1NX91_CHICK/659-713 AC F1NX91.1
#=GS C9R960_AMMDK/396-435 AC C9R960.1
#=GS F9N0B3_PEPMA/352-395 AC F9N0B3.1
#=GS D9TLN7_THETC/408-460 AC D9TLN7.1
B4KS80_DROMO/668-720 ............ALKSAEAMYKKYIQKINE..EP-..SCPLCHHNMSGDEA..CDLTTELTDEIQKLPDNI-s...............
G1RQJ8_NOMLE/662-717 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
Q6FNZ8_CANGA/659-713 ............KMHQTTLEFNRKALEVAI..NND..CCYLCSRSFENTEF.rSKILKELKEKTDTKFEES-l...............
G3H2B1_CRIGR/1-56 ..........ml--GGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTETE.lQEVISDLQSKLRLAPDKLK................
G8JMK8_ERECY/651-705 ............KMHRTTLEFNLKALEIAE..NDH..CCYLCQRKFQNDVE.kANLLEELHSKTKSDFEQT-l...............
E7EN38_HUMAN/597-652 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
Q28ZL9_DROPS/668-720 ...........a-HKSAEALYKKYIQKINE..EP-..CCPLCHHNMSGDEA..CDLTTELSDEIQKLPDNI-s...............
RAD50_ARCFU/415-468 ...........s-LKTRGAQLKKAVEELKS..AER..TCPVCGRELDEEHR..KNIMAEYTREMKRIAEEL-a...............
H3F7F3_PRIPA/12-66 ...........p-LEASATLYAKWADETKE..KK-..CCPVCERTFGRDNEgvSKLARKLADLSFSIPKE--sa..............
H3ZM36_THELI/419-479 ............KLRSLSGEKDKAISELMK..AKG..RCPVCGAELTDEHR..EELIKSYKIEIKK------ymermkelekeek...
H2C3I3_9CREN/400-452 .......enlqq-------ELMRSLESLRE..AKG.gKCPVCGGPLDEEHR..ILLITDTEKKLSESRKRI-e...............
E9JDB3_SOLIN/670-717 ........hqal-------AYKEYVAKLSL..KNP..CCPLCHRNFEKEDT.vANLIEEIENDI--------irsq............
E7Q876_YEASB/631-685 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
Q5SV02_MOUSE/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
RAD50_PYRKO/418-471 ............ELKSIAGERNKALMELKK..AKG..RCPVCGRELTEEHR..KELLEKYTAELKEISAEMK................
A0SQ61_9SACH/665-719 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENELF.kSKLLQELKTKTDANFEKT-l...............
RAD50_THEVO/434-486 ............AMRSHKMEVEENAAMLSG..RG-..VCPVCGTHLGTEKS..EDLVKHYGEEASRLEEDIN................
B0XC38_CULQU/107-148 .........ssr-----------------N..ATQ..RCPCCQRALGSEQFiyCRVYQEVNEMIDRLPSKL-d...............
RAD50_SULAC/414-468 ...........d-LNGRKEQTLKIYNNLNS..IED.dRCPICGRPLDSEHK..AKIREEIKVQLLELNKQI-t...............
F1RJV2_PIG/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
E0SP05_IGNAA/355-406 ..........ke---AELKLNRDSINIIRE..ST-..VCPLCGRELSLDLR..EKLSRDIDLRIEFLEKS--le..............
G1N9X5_MELGA/659-713 ............-LAGATAVYSQFITQLTE..ENQ.sCCPVCQRVFQTEAE.lQDVISDLQSKLRLAPDKLK................
D3ENY1_UCYNA/479-528 ...........k----EIDKLQQKIHELNI..YHS..NCPLCEQKLDRNRR..HDVIKKIARQYKNIQKQ--i...............
Q6CUR2_KLULA/651-705 ............KMHKTTLEFNLKALEVAK..NED..CCYLCQRKFNDVTS.sSKLIEDLKARTNKNFQ---ial.............
A6ZRJ3_YEAS7/665-719 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
F7DGI4_MACMU/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
Q8YQ48_NOSS1/476-528 ......eyerll------GEMEQKLQMLRN..PDA..ICPLCERPLDEHHW..NRVVDKTKDEYKETE----gql.............
G3V9X6_RAT/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
B4I847_DROSE/668-720 ............ALKSSEALYKKYIQKMDE..EP-..SCPLCHHNMTSDEA..CDLTSELTDEIQKLPDNI-t...............
RAD50_MOUSE/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
RAD50_DROME/668-720 ............ALKSSEALYKKYIQKMDE..EP-..SCPLCHHNMTSDEA..CDLTSELTDEIQKLPDNI-t...............
F4WFQ0_ACREC/667-710 .........qat-------AYKEYVKKLS-..VKN.pCCPLCHRNFEKQNN.vTDLIKEIESDI--------i...............
G5J0N6_CROWT/101-152 .........nte----KIEELQQKINLLNN..PDS..ACPLCEQELDENRR..NNVVDKTYQQQQKLQE---qi..............
RAD50_CAEEL/645-698 ...........p-LSAKSNLYDSYIEESKS..SG-..CCPLCDRDFKTKKE.iNEFSKKLENMTLSFPTEQE................
G3QBX6_GASAC/659-714 ............MLAGATAVYTQFISQLTE..ETE.pCCPVCQRTFPSDSD.lQEVISDMQSKLRLVPDKLK................
G2SF07_RHOMR/490-543 ......elerqq------QELQQRYDTFRQ..AEA.dECPVCGSELGPEHR..QEVERHYEEQLETL-----argl............
G1U4Q5_RABIT/656-711 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
H9YVE3_MACMU/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
RAD50_HUMAN/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
C5XSH1_SORBI/106-147 .........feh---------------LAR..KNH..VCPCCERAFTPDEE..DEFVKKQRMQNSSTAEKSK................
F0QT70_VULM7/386-438 ..........rv--NAEIEHIELELNLLRG..GQV.eKCPLCGRPLSRDSA..QELVASREARLREL-----grr.............
B4GHK9_DROPE/668-720 ...........a-HKSAEALYKKYIQKINE..EP-..CCPLCHHNMSGDEA..CDLTTELSDEIQKLPDNI-s...............
D3ZPN8_RAT/597-652 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
F0LM45_THEBM/418-471 ............ELKNATSEKNKAILELRK..AKG..KCPVCGAELTEKHR..EDLIKKYTLEIESYAKEM-e...............
C7P7E8_METFA/481-534 ............EINNEINRLKKILDELKD..VEG..KCPLCKTPIDENKK..LDLINSHKSQLDNKYNELE................
A4YET5_METS5/397-451 ...........e-RKVEYDQIRKSLDALLS..ATE.gKCPVCGGPLDEPHR..QELTQKYRQRLTELSKELK................
Q16FI3_AEDAE/409-461 ............ELRSAEVLYKKYISRIED..DK-..CCPVCHKGMDGADV..QDISSELSDEIRRLPEKIE................
B9S9Y8_RICCO/677-726 ..gmrqmfdpfe----------R----VAR..AHH..VCPCCERPFSAEEE..DEFVKKQRVKAASSAEHMK................
E6UPU3_CLOTL/439-481 ....nkkeiqen--------LNIYIDILRK..SG-..VCPLCKSSIGDEKL..ENIIRHYEE----------................
G7MUA6_MACMU/635-690 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
B4VXN7_9CYAN/477-527 .........yek----QIAELTQKIQMLQV..QDA..VCPLCDRPLDETHS..QHVIQKTSTEQQEI-----qdq.............
A5JYU5_CAEEL/659-712 ...........p-LSAKSNLYDSYIEESKS..SG-..CCPLCDRDFKTKKE.iNEFSKKLENMTLSFPTEQE................
G0UC67_TRYVI/670-721 ..........ar--HAMTACYSHLVEMANA..SG-..KCPLCDRSFESEEE.rSNFLRLYE-----------kqqstsaqe.......
Q6L2H8_PICTO/420-469 .........enl------DELSRNMEILNG..QS-..VCPVCGTTLGEDKI..NHIINDYNNKKSGIESKI-r...............
G9KJY1_MUSPF/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
B5FW66_OTOGA/658-713 ............MLAGATAVYSQFITQLAD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
RAD50_SCHPO/653-705 ...........s-LQFGSTFYEKAIEICVD..QH-..ACQLCQRSLDKEEE..KLFVEHCHSMIDVIPSKS-a...............
RAD50_PYRFU/422-475 ............ELKNKIGDLKTAIEELKK..AKG..KCPVCGRELTDEHR..EELLSKYHLDLNNSKN---tla.............
#=GR RAD50_PYRFU/422-475 SS ............HHHHHHHHHHHHHHHHTT..-SE..E-TTT--EE-HHHH..HHHHHHHHHHHHHHHH---HHH.............
C7GPB1_YEAS2/665-719 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
E8T6E8_THEA1/420-473 ...........t-LNEQVELLKKRLQTLET..AES..ACPICGSKLTPEKK..ERLLEETRQELNS------sltlie..........
D7LEB9_ARALL/647-695 ..mrkmfepfed---------------LAR..QHH..YCPCCERSFTTDEE..NSFVKKQRVKASTTGEQLK................
Q533U0_MUNMU/69-123 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRGFQTEAE.lQEVISDLQSKLRLAPDKL-................
B3NNP5_DROER/668-720 ............ALKSSEALYKKYIQKMDE..EP-..CCPLCHHNMTSDEA..CDLTSELTDEIQKLPDNI-t...............
D3E346_METRM/461-514 ............SLKQEIKSLDEPLADIKK..VEN..KCPVCQSEISEDKK..NELINGYEATISGN-----tkrin...........
I1P0L1_ORYGL/677-726 ...........g-MRQMYEPFENLARELH-..---..MCPCCQRAFTPDEE..DEFVKKQRTTCES------taermn..........
B7P1K3_IXOSC/622-668 ...........m--------FRKYIERMRQ..SP-..CCPLCKRHFEELEL.vNRLIEDLEKKMRILPEELN................
F0NFK6_SULIR/403-457 ...........k-VESLISEKNEIINNLSQ..VKG.eTCPVCGRPLDEEHK..QKIVEEAKSYISRLEL---dkn.............
F6SPI9_XENTR/661-716 ............MLAGATAVYTQFITTLTE..ENQ.pCCPVCQRIFPSEAE.lQDVINDMQSKLRLVPDKLK................
C5A1H5_THEGJ/416-468 ...........s-LRGKRAELEANMERLEG..AK-..ICPLCRRPIDEHEE..GEILAEYRAEISRIESE--vk..............
D0KUC4_SULS9/403-457 ...........k-VESLISEKNEIINNISQ..VEG.eTCPVCGRPLDEEHK..QKIIKEAKSYILQLELN--kn..............
B0JQH4_MICAN/479-529 .........eeq-----LLELTDKLEKLNI..PDS..VCPLCEQNLDSHHR..HQVIRKTHQHQEQIQEQ--i...............
RAD50_METKA/410-465 ............EIRVKEKELLERIESLRE..AEG..ECPVCLRKLPRERA..EKLLRDAEKELERL-----qgreedl.........
C7SB53_PLADU/580-633 ...........v--QGTLVVLKKYIEKLRK..DDA..PCPLCRRNFDAQSE.iDELIRDLEDKMENLPSKM-t...............
Q7RVZ9_NEUCR/669-723 ............ELNMYLKEYFLKAKVKAE..EKH..KCYLCEQSLGDEKT.mKRLMKRIQDKIDDKDR---del.............
I0A1C6_9CREN/460-512 ...........i--ESSLKTFKEYINEIKR..AEG..RCPLCGRELNEEHK..VELIHKFEEAINNNI----nekk............
B4MJF7_DROWI/669-721 ...........a-LTSAEAMYKKYIQKITE..EP-..CCPLCHHNMSGDEA..SDLSYELTDEIEKLPENIE................
E7KHE0_YEASA/631-685 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
RAD50_AERPE/440-495 ............ALEAEARRLVQALSMLEE..SGGsaRCPVCGAELPPGRA..EAIARHYRHEAERLRKAAK................
G3T4B6_LOXAF/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTETE.lQEVISDLQSKLRLAPDKLK................
RAD50_RAT/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPGCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
H0UY19_CAVPO/662-717 ............MLAGATAVYSQFITQLTH..EKQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
C3N8B7_SULIY/403-457 ...........k-VESLISEKNEIINNLSQ..VKG.eTCPVCGRPLDEEHK..QKIVEEAKSYISRLEL---dkn.............
RAD50_METMP/475-526 ...........k-KESKISEYKNSKAELEK..TKD..SCHVCQSKITEEKK..QELLEKYNSEIQN------eqls............
E2A7J8_CAMFO/666-712 .........qat-------AYKEYIKKLS-..VKD.pCCPLCHRNFQEQNK.vTDLIKEMETDI--------irnq............
B0WAP9_CULQU/668-720 ..........eq--RSAEILYRKYISRIED..DS-..CCPLCHKEMAGSDA..QDISTELSDEIRRLPEKIE................
D1NIQ0_CLOTM/439-481 ....nkkeiqen--------LNIYIDILRK..SG-..VCPLCKSSIGDEKL..ENIIRHYEE----------................
H0GM90_9SACH/631-685 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTGANFEKT-l...............
D0MI39_RHOM4/490-543 ..elerqqqdlq----------QRYDTFRQ..AEA.dVCPVCGSELGPEHR..EEVERHYEEQLEEL-----argl............
C3N0D1_SULIA/403-457 ...........k-VESLISEKNEIINNLSQ..VKG.eTCPVCGRPLDEEHK..QKIVEEAKSYISRLEL---dkn.............
B2KIE7_RHIFE/658-713 ............MLAGATAVYSQFITQLTD..DNQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
C9RHD0_METVM/477-530 ............ELNSEISQLKKILNELEK..VEG..RCPLCKTPIDEKRK..MELINQHKLKLSEKLKELK................
F0NMQ6_SULIH/403-457 ...........k-VESLISEKNEIINNLSQ..VKG.eTCPVCGRPLDEEHK..QKIVEEAKSYISRLEL---dkn.............
H2PGI2_PONAB/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
B4MFQ7_DROVI/669-721 ............ALKSAEAMYKKYIQKIDE..EP-..SCPLCHHNMSGDEA..CDLTTELTDEIQKLPDNI-t...............
Q6MGE2_NEUCS/669-723 ............ELNMYLKEYFLKAKVKAE..EKH..KCYLCEQSLGDEKT.mKRLMKRIQDKIDDKDR---del.............
D1C4W6_SPHTD/403-454 ...........r-LRADMEEIKARLDQIEG..AGA..LCPVCRRELGEDER..QRLRTEYTAE---------gkalgdq.........
B5IGG2_ACIB4/391-444 ...........a-INTKIEELRKELEDYKS..LGA..VCPKCKRPLTEEHK..KKLISETIAKIEDRKEDL-r...............
B6JYL6_SCHJY/623-675 ...........s-LQFGVLFYERAIKVSDE..KH-..ACQLCRRGLDDSER..KEFTKYCNSMVLTIPSKA-q...............
F4B9U7_ACIHW/402-456 ...........a-IKGRKEQLIQIIKNLEN..IKE.nRCPVCGRELTEEHR..KKIKIEAETEVKDIEKKL-s...............
F6RZ99_CIOIN/234-288 .........iqy----MYREFIKKLTNETD..KSE.aACPICMRCFEETSE.vDELVEDLQTKLNMAPEKL-a...............
G5ASP8_HETGA/687-742 ............MLAGATAVYSQFITQLTD..ENE.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
C6A1X5_THESM/362-414 ...........e-VSGRINDLRKALDMLGE..SE-..ACPVCKTKLTPEHR..DRVKHEMEEEIKSLEE---ivk.............
A9A9X2_METM6/475-527 ...........k-KESKILEIKNSKTELEK..TKD..SCHVCQSKISEEKK..QELLEKYTSEIQNE-----elsa............
G0EHQ4_PYRF1/436-489 ...........n-IESKIHDIEENIVKLAS..AHG..RCPLCSRPLRDEER..RDLIRKLRFEKEALREKLE................
I1MYA5_SOYBN/678-724 ..mrqmfdpfer---------------VAR..ANH..VCPCCERPFSPEEE..DSFVKKQRVKAT-------ssagh...........
E0W0B2_PEDHC/660-713 .....lsssefm--------YQRYIRALEK..TEP..CCPLCHRDFTRESD.aRSLVEELNSKIRQVPR---rlq.............
F6RT86_MONDO/658-713 ............MLAGATAVYSQFITQLTD..EKQ.sCCPVCQRVFQTEAE.lQDVISDLQSKLRLAPDKLK................
D2A5X5_TRICA/668-718 .........kii--------YNQYIKKFEE..ERP..CCPVCETNFSGKTTvvGKIITTLKSKLDKVPQQL-a...............
G3X6W2_BOVIN/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRGFQTEAE.lQEVISDLQSKLRLAPDKLK................
F8AI78_PYRYC/419-472 ............ELESRMLDREKAIEELKR..ARG..KCPVCGTELTEEHR..QELIEKYTLEVSGMEE---rlr.............
Q4RIQ9_TETNG/658-713 ............MLAGATAVYTQFISQLTE..ERE.pCCPVCQRTFPMESE.lQEVISGMQSKLRLVPDKL-r...............
RAD50_ARATH/677-726 ...........g-MRQMFEPFEKRARQEH-..---..SCPCCERSFTADEE..ASFIKKQRVKASSTGEHLK................
Q752D9_ASHGO/650-704 ............KMHRTTLEFNQKALEIAE..TTN..CCYLCRRNFDKDSE.rSKLIEELKSRTNTAFEKT-l...............
E2B8W9_HARSA/666-713 .........qat-------AYKEYIKKLSM..KDP..CCPLCHRDFQEQKK.vTELIKEMESDI--------irnqp...........
A8YKL8_MICAE/481-531 .........eeq-----LLELTDKLEKLNI..PDS..VCPLCEQNLDSHHR..HQVIRKTHQHQEQIQEQ--i...............
A8ACA9_IGNH4/415-467 ..........lv--EVMLDERRRAIEMLRG..RD-..SCPVCGSPLPPERR..ESLIRRYAEEVAKFEEKL-t...............
H1KYJ1_9EURY/472-525 ............EVKSKINALKKALSEIEK..VRG..RCPVCSSEIDEKKK..KELKEEYSKNLKEEEERLK................
E3LQ28_CAERE/659-712 ...........p-ISAKSDIYDSYIEETKT..SV-..CCPLCERDFSTKKE.iTAFSKRLQNMTLNLPAEQE................
E3X070_ANODA/249-301 ...........e-ARSAVVLFQKYISNINS..AH-..CCPVCDKEMTSDDA..LDVSGKLSDEIRRLPQKIE................
I0I7E2_9CHLR/439-491 gaeitnlrqqst--------------ALEN..TDT.aLCPVCEQPLTPEHR..RELLARNAAQMEALAQE--ra..............
H3JGN1_STRPU/743-797 .......altgs-----KHLFDRYIQSLQR..TDA..LCPLCHRGFDSGAE.vQELVQELQDKLRLAPSKL-a...............
H8EBX3_CLOTM/439-481 ....nkkeiqen--------LNIYIDILRK..SG-..VCPLCKSSIGDEKL..ENIIRHYEE----------................
F6W0H6_XENTR/657-712 ............MLAGATAVYTQFITTLTE..ENQ.pCCPVCQRIFPSEAE.lQDVINDMQSKLRLVPDKLK................
G0V5A1_NAUCC/657-711 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFETADF.kSKLLQELKAKTDANFETT-l...............
F7AR56_HORSE/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
A0ZDB3_NODSP/476-527 .......eyerl-----LAELEQKLEMLRT..PDA..MCPLCERPLDEHHW..NRVVDKTKDEYQD------tegq............
Q7Y239_ORYSJ/677-725 ...........g-MRQMYEPFENLARELH-..---..MCPCCQRAFTPDEE..DEFVKKQRT----------tcestadrm.......
G8ZSI8_TORDC/658-712 ............KMHQTTVEFNKKALEVAE..RED..SCYLCSRKFETEQF.rSSLLAKLRVKVDSRFEQT-l...............
C4N9Q9_XENLA/658-713 ............MLAGATAVYTQFITTLTE..ENQ.pCCPVCQRIFPSEAE.lQDVINDMQSKLRLVPDKLK................
B9AD32_METSM/447-512 ..........kf--KQAIETAQKPLDELGD..VEN..KCPVCQSDINPQKK..NELIDSYNNEIKINEKS--ieenkenirllnkn..
Q9C499_NEUCS/669-723 ............ELNMYLKEYFLKAKVKAE..EKH..KCYLCEQSLGDEKT.mKRLMKRIQDKIDDKDR---del.............
F1NEG1_CHICK/659-713 ............-LAGATAVYSQFITQLTE..ENQ.sCCPVCQRVFQTEAE.lQDVISDLQSKLRLAPDKLK................
C0QRS0_PERMH/437-488 ............EIEAEGKELKKKREKIDS..LEG..SCPTCERPLDQHTK..DELVKEIDQKLEYLR----kr..............
G8BQ10_TETPH/656-708 ............KMHQTTLAFNRKALEVAE..NSN..CCYLCSREFDSTGL.kSKLLNELKAKTNQQFE---l...............
RAD50_PYRHO/419-472 ............ELNQRSKDRRLAIIELKK..ARG..KCPVCGRELTEEHK..ADLLRKYSLELSSIEKEI-q...............
B5IAI0_ACIB4/391-444 ...........a-INTKIEELRKELEDYKS..LGA..VCPKCKRPLTEEHK..KKLISETIAKIEDKKEEL-r...............
B9F043_ORYSJ/968-1015 ...........g-MRQMYEPFENLARELH-..---..MCPCCQRAFTPDEE..DEFVKKQRT----------tcestadr........
H3GXW6_PHYRM/387-436 ....rknmvmfl-----------NIYKKKG..IKD.hCCPLCERDMTPEEE..QAFDSILSDKTDD------rkva............
E7QJM6_YEASZ/665-719 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
B7NZL1_RABIT/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
F7EPF8_ORNAN/658-713 ............MLAGATAVYSQFITQLKD..EKQ.sCCPVCQRVFQTEAE.lRDVISDLESKLRLAPDKLK................
E9QPC6_MOUSE/597-652 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
D0Z764_DROME/672-724 ............ALKSSEALYKKYIQKMDE..EP-..SCPLCHHNMTSDEA..CDLTSELTDEIQKLPDNI-t...............
F0TBV3_METSL/437-490 ...........n-LKTQSNDLKKPINELEA..VKE..KCPICESEIDETKR..NELINRYQSQIDTNTNKI-s...............
D5U1T6_THEAM/462-516 ........srqa----LKQQVEKSIELLET..SPQ.pECPVCKRPLEGSRK..EEILADYRKHLAELEKEL-r...............
RAD50_THEAC/434-486 ............ALRQKEEEIRRNMNMLEG..HN-..KCPVCGTDLGDEGS..RRIREHYSEDLNRLNEEI-d...............
G2WLL6_YEASK/665-719 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
C7DHY0_9EURY/369-419 ...........s---SRAEELKELIAELDR..HKG..VCPVCEREFEEGLR..ERLLKKNKEELESLKG---kl..............
F6BLP7_THEXL/399-460 ..aeykvqldnf--NKKTEELKENYKAILQ..TGA..KCPLCNSPLDENKK..SGLLNDIKKEINDISNKI-y...............
G7JAR6_MEDTR/886-934 ..mrqmfdpfer---------------VAR..AHH..FCPCCERSFSAEEE..DSFVKKQRGKAASSAEHLK................
A6UUX2_META3/475-529 ...........q-NNAEINQTKDAIEKLKG..TTE.dKCPVCQSNIDGLKK..QELLKQYNQLIEERKQKS-n...............
G0MP92_CAEBE/671-724 ..........pi--SAQSDLYETYIEETKT..SG-..CCPLCDRDFSTKKE.iNEFTKRLKNMTLSFPAKNK................
A8Y3Y7_CAEBR/702-755 ...........p-ISAKSDIYDSYIEESKT..NG-..CCPLCERDFSSKKA.iSEFTKKLQHMTLNLPAEQE................
B8AIA2_ORYSI/677-726 ...........g-MRQMYEPFENLARELH-..---..MCPCCQRAFTPDEE..DEFVKKQRTTCES------taermn..........
F8AKK1_METOI/479-532 .........ekd---TKIKQIKDAIKKLEE..TDN..KCPVCQSDIDENKK..AELLNTYHSNIEKE-----lkqlk...........
C8ZFY7_YEAS8/665-719 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
B9GFJ5_POPTR/677-726 ..gmrqmfdpfe----------R----VAR..AHH..VCPCCERPFSAEEE..DEFVKKQRVKAASSAEHMK................
A6VGS8_METM7/475-526 ...........k-KESKISEYKNSKAELEK..TND..SCHVCQSKISEEKK..QELLRKYNNEIQN------eqls............
RAD50_SULSO/403-457 ...........k-VESLISEKNEIINNISQ..VEG.eTCPVCGRPLDEEHK..QKIIKEAKSYILQLELN--kn..............
A3IMA1_9CHRO/122-172 ..........te----KIEELQKKINLLNN..PES..TCPLCEQNLDESRR..HHVIEKTNKQQEQLQ----qqi.............
D7E132_NOSA0/478-525 ........ekll------GELEQKLQVLQS..PNA..LCPLCERHLDEHHW..SRVIQKTQLEY--------edtq............
H2WAC9_CAEJA/447-500 ..........pi--SAKVDLYDTWIESTNS..SG-..CCPLCDRDFSSKKE.iSEFSKRLQNLTLNFPAEQE................
D2ZRK4_METSM/447-500 ..........kf--KQAIETAQKPLDELGD..VEN..KCPVCQSDINPQKK..NELIDYYNNEIKINEKS--ie..............
A3DDZ9_CLOTH/439-481 ....nkkeiqen--------LNIYIDILRK..SG-..VCPLCKSSIGDEKL..ENIIRHYEE----------................
G4XIR2_9BRYO/675-725 ...........g-MKKMFDPFEKQARNTH-..---..ACPCCERGFTPEEE..DEFVRKQR-----------inassytdklre....
C4KJH9_SULIK/403-457 ...........k-VESLISEKNEIINNLSQ..VKG.eTCPVCGRPLDEEHK..QKIVEEAKSYISRLEL---dkn.............
A8MDQ4_CALMQ/387-441 ............SLKSELSHIEEELNVLKS..SKE.pVCPVCKRPLKPEDR..ERLIKENNEKLRLIREEI-r...............
RAD50_PYRAB/420-473 ............QMEQEKNERMKAIEELRK..AKG..KCPVCGRELTEEHK..KELMERYTLEIKKIEEELK................
B1X172_CYAA5/478-528 ..........te----KIEELQQKINLLNN..PES..TCPLCEQDLDENRR..HHVIDKTNKQQEKLQQ---qi..............
F6BAS4_METIK/472-525 ............EVRSKINALKKALNEIEK..VEG..RCPVCNSEISEEKK..KELKEEYSKNLKEEEERLK................
B3MEF0_DROAN/667-718 ............ALKSAEALYKKYIQKIEE..EP-..CCPLCHHNMSGDEA..CDLTTELTDEIQKLPENI-................
B3LP94_YEAS1/665-719 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
F7VKE1_SORMK/670-724 .........eld---EYLTEYFTSAKEAAE..EKK..TCYLCDQSLANEKV.mQKLMKKIRKKLDDKHK---deq.............
B4P7X9_DROYA/668-720 ............ALKSSEALYKKYIQKMDE..EP-..CCPLCHHNMTSDEA..CDLTSELTDEIQKLPDNI-t...............
H2S8G2_TAKRU/658-713 ............MLAGATAVYTQFISQLTE..ERE.pCCPVCQRTFPSESE.lQEVISDMQSKLRLVPDKL-r...............
E8MYK6_ANATU/403-454 .........rlq----QMNEIKERMERLSQ..ASG.aLCPLCGQPLGEEER..QNLIASLEQQ---------gkqlgdt.........
B7R252_9EURY/416-468 ............SLKGKKAELMANMERLEG..AK-..ICPLCRRPIDEHEE..GEILAEYRAEISRIEGE--vk..............
B4J9P7_DROGR/662-714 ............ALKSAENMYKKYIQKINE..EP-..SCPLCHHNMSGDEA..LDLTTDLTDEIQKLPDNI-a...............
B3QT75_CHLT3/414-467 .......radee-----TEDITNKGKTLKD..INT.aECPLCRSPLDEQHR..QHILDEYRNAFREL-----qnlq............
B1MTQ1_CALMO/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTETE.lQEVISDLQSKLRLAPDKLK................
B2J0P5_NOSP7/478-525 ........ekll------GELEQKLQMLQN..PEA..LCPLCERPLDEHHW..SRVVEKTQAELED------tq..............
F0LKK5_THEBM/428-480 ............KLEGRINDLQQALSMLGE..SD-..TCPVCKTKLTPEHR..DKVKSEMQEEIRGLKEEI-r...............
F4HJV8_PYRSN/419-472 ...........e-VSQGIRERKKAIDELRR..AKG..KCPVCGRELTEEHK..AKLITKYSKEIKRLEEELE................
H3IRN8_STRPU/545-598 .......altgs-----KHLFDRYIQSLQR..TDA..LCPLCHRGFDSGVE.vQELVQELQDELRLAPSKL-................
C5DYV4_ZYGRC/657-711 ............KIHQTTLEFNKKALEVAK..TES..CCYLCTRKFDDEGF.kSSILLRLQEKTDGKFNTI-l...............
E7KTA1_YEASL/631-685 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTXANFEKT-l...............
C3MTS1_SULIM/403-457 ...........k-VESLISEKNEIINNLSQ..VKG.eTCPVCGRPLDEEHK..QKIVEEAKSYISRLEL---dkn.............
G4YI53_PHYSP/713-758 .....knmvmfl-----------NIYKKKG..IKD.hCCPLCERDMTPEEE..QAFEAILSDKTD-------dg..............
A5UJE7_METS3/447-512 ..........kf--KQAIETAQKPLDELGD..VEN..KCPVCQSDINPQKK..NELIDSYNNEIKINEKS--ieenkenirllnkn..
A7RWC7_NEMVE/211-266 .........asi-----EKIYQKYIKKLTDpsVKN.dGCPLCHRRFEANAQ.iKTLVDELKTKMRDLPAKT-a...............
G1KMS1_ANOCA/659-714 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFGTESE.lQEVIDDLQKKLRLAPDKLK................
D7FB72_9HYME/91-142 .......fqgta--------YSEYVKKLSE..PDP..CCPLCDRDFPKSSD.aLKVADKLKEEIRNHPDRLK................
D2GVH6_AILME/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
H2QRG6_PANTR/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
G0WD57_NAUDC/658-712 ............KMHQTTLDFNRKALEIAD..RDN..CCYLCARKFETDDF.rGKILQQLRAKTDANFENT-l...............
H3DLI5_TETNG/658-713 ............MLAGATAVYTQFISQLTE..ERE.pCCPVCQRTFPMESE.lQEVISGMQSKLRLVPDKL-r...............
C3PT86_DASNO/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQDIISDLQSKLRLAPDKLK................
H9KYC4_CALJA/311-366 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
A4FWH8_METM5/475-527 ...........k-KESKILETKNYKLELEK..TKD..SCHVCQSKITEEKK..QELLKKYTSLIQN------eglsi...........
A8UZN2_9AQUI/437-490 ............SLKSKTEELNEQIKNISK..LEG..NCPTCARPLKQHSK..EEIIKDLKQKITKLQNQLK................
Q7NCW4_GLOVI/469-529 ..klraqqqqyr---KELDQLAEKAALLAQ..GET..DCPLCGGPLDAEHR..ELLGEQHQRQHAELEDHL-t...............
RAD50_YEAST/665-719 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
G1PUW7_MYOLU/662-717 ............MLAGATAVYSQFITQLTD..ESQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
G0H206_METMI/475-528 ..........kk--ESKISETKNSKAELEK..TKD..SCHVCRSKISEEKK..QELLEKYNSEIEN------eklste..........
E2QT24_CANFA/660-715 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
D2RFR1_ARCPA/414-466 ...........r-LESEIERLKEALNALKS..AKG..VCPTCGRLLSEDDR..LNLIKSYTKKLENVRKD--l...............
B6YXU9_THEON/418-471 ............ELKNRVSERNKAIIELKK..AKG..KCPVCNRELTEEHR..KGLMERYLAEVKDVSKEIK................
G8LZ19_CLOCD/436-482 ........lnnn--KQEIEKYLNMYTELLK..ESG..KCPLCNSKISDDKL..GEIIKHYKE----------a...............
C1DVT9_SULAA/430-497 ...........d-IEAEGKQLKEKLSNLSS..IHG..DCPTCGRPLEEHQK..EELINEINKVLEEKRNK--hkqltqkqkeieeelk
I1CMI7_RHIO9/533-593 ...........n-IHGAELIYGKFFEKAKA..SK-..CCPLCTRGFGEDAQ.nDAFQGKLQTIMKRIPDQ--reklneklk.......
G3QFG8_GORGO/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
B0KWP2_CALJA/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
H8EJU5_CLOTM/439-481 ....nkkeiqen--------LNIYIDILRK..SG-..VCPLCKSSIGDEKL..ENIIRHYEE----------................
G1MH82_AILME/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
Q32P42_HUMAN/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
G3WB07_SARHA/660-715 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQDVISDLQSKLRLAPDKLK................
F0S398_DESTD/426-480 ...........t-IEAKLEEVEKRIKILES..SES.lSCPVCGSPMDKVEK..EKFLLDSKKEIDN------sikvlk..........
B2G497_ZYGRO/657-711 ............KIHQTTLEFNKKALEVAK..TES..CCYLCTRKFDDEGF.kSSILLRLQEKTDGKFNTI-l...............
G6GWV6_9CHRO/478-528 ..........te----KIEELQQKINLLNN..PES..TCPLCEQDLDENRR..HHVIDKTNKQQEKLQQ---qi..............
C5DKA6_LACTC/651-705 ............KMHKTTLEFNLKALEVAK..ENN..CCYLCQREFHDGKE.qSTLLKELQSRTDTKFEET-l...............
Q8DGY7_THEEB/476-526 .......eyerq-----IHQLEQRLELLNQ..PGA..ICPLCQRPLDREHY..QAVRQRHIAEKEE------lln.............
F1Q537_DANRE/658-713 ............MLAGATAVYSQFISQLTE..EGD.pCCPVCQRVFPSEAE.lQDVINDMQSKLRLVPDKLK................
G6FW84_9CYAN/479-529 ........erll------GELEQKIQMLQT..PNA..LCPLCERPLDEHHW..NRVVDKTKSEYKDA-----egql............
B4QH58_DROSI/668-720 ............ALKSSEALYKKYIQKMDE..EP-..SCPLCHHNMTSDEA..CDLTSELTDEIQKLPDNI-t...............
Q5W4T6_CHICK/659-713 ............-LAGATAVYSQFITQLTE..ENQ.sCCPVCQRVFQTEAE.lQDVISDLQSKLRLAPDKLK................
B5VQF9_YEAS6/665-719 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
D9Q224_ACIS3/450-504 ...........s-VRQRALQLNDIVKVLGT..SGE.aRCPVCGSPLSPERK..EELLKHFDNERKGLAT---eer.............
H0YT14_TAEGU/659-713 ............-LAGATAVYSQFITQLTE..ENQ.sCCPVCQRVFQTEAE.lQDVISDLQSKLRLAPDKLK................
D2PDY1_SULID/403-457 ...........k-VESLISEKNEIINNLSQ..VKG.eTCPVCGRPLDEEHK..QKIVEEAKSYISRLEL---dkn.............
RAD50_SULTO/417-471 ............EIKGRIEELNKLLGNLNQ..VKG.nVCPVCGRELSDDHK..RKIQNEIIEKLKELDEL--nk..............
A2BM16_HYPBU/437-490 .........akl---NEKEYIEGILLKLTS..ASG..RCPLCGRPLTEEHR..MTLISKFRSEKRGVETEIK................
D0MSB2_PHYIT/682-730 ...rrknmvlfl-----------NIYKKKG..LKD.hCCPLCERDMSPEEE..QAFESVLSDKTD-------dgk.............
F6VU98_XENTR/658-713 ............MLAGATAVYTQFITTLTE..ENQ.pCCPVCQRIFPSEAE.lQDVINDMQSKLRLVPDKLK................
C3MJD9_SULIL/403-457 ...........k-VESLISEKNEIINNLSQ..VKG.eTCPVCGRPLDEEHK..QKIVEEAKSYISRLEL---dkn.............
G6DRY5_DANPL/622-668 .........iit----------KYKGQIKD..NN-..CCPLCSRGFDNEDE.vNDLISQLTTQVMNVPAKLE................
D3ZBK7_RAT/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
F4G3H5_METCR/399-448 ....lelelvqi---------RKGREALIS..ANE.gKCPVCGGPLDEAHR..KELIDKYDRR---------ereiv...........
G0HJU4_THES4/418-469 .......lnglk------ESLIENLSKLEG..AR-..VCPLCKRPIGEHDE..EEIRAEYDAEITSIEKKLN................
RAD50_METJA/480-533 ............EINSEIKRLKKILDELKE..VEG..KCPLCKTPIDENKK..MELINQHKTQLNNKYTELE................
A0SQ62_SACPS/665-719 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENESF.kSKLLQELKTKTDANFEKT-l...............
Q7QAJ3_ANOGA/669-721 ...........e-ARSAVVLYQKFIANIDN..DR-..CCPVCEKGLESEDA..HEVSGKLGDEIRRLPEKIE................
G7P885_MACFA/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
D3S7S2_METSF/481-534 ............EINNEINRIKKVLNELKD..VEG..RCPLCKTPIDDIKK..QELINSHKSQLNSKYKELE................
A9CB11_PAPAN/658-713 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
A8Y5I3_MOUSE/597-652 ............MLAGATAVYSQFITQLTD..ENQ.sCCPVCQRVFQTEAE.lQEVISDLQSKLRLAPDKLK................
H9HGI0_ATTCE/666-712 .........qat-------AYKEYVKKLS-..VKN.pCCPLCHRNFEKQNN.vADLIKEIESDI--------irnq............
H2AUH4_KAZAF/656-710 ............KMHQTTLDFNRKALEVAE..YDN..SCYLCLRSFDTVEF.kNEILQNLKAKTEAKFET--al..............
C7HHM4_CLOTM/439-481 ....nkkeiqen--------LNIYIDILRK..SG-..VCPLCKSSIGDEKL..ENIIRHYEE----------................
H3A560_LATCH/537-592 ............MLAGATAVYTQFISQLTE..DNQ.pCCPVCQRVFPSEAE.lQDIINDLQSKLRLVPDKLK................
B0W2Q1_CULQU/75-116 .........ssr-----------------N..ATQ..RCPCCQRALGSEQFiyCRVYQEVNEMIDRLPSKL-d...............
Q5XH50_XENLA/658-713 ............MLAGATAVYTQFITTLTE..ENQ.pCCPVCQRIFPSEAE.lQDVINDMQSKLRLVPDKLK................
H0H044_9SACH/635-689 ............KMHQTTLEFNRKALEIAE..RDS..CCYLCSRKFENDSF.kSKLLQELKIKTDANFEKS-l...............
F6D565_METSW/436-488 ..........nl--KTHNKNLEKPVKELEN..VKD..KCPVCKSTISPDKR..DELIEGYDCEIKSNKD---ri..............
D5VSC5_METIM/411-464 ...........n-IEKEIKEKKKAINELKE..AKG..KCPVCGAELTEEHK..ERLINEYKEEIKDL-----lkrkk...........
Q17AN3_AEDAE/392-444 ............ELRSAEVLYKKYISRIED..DK-..CCPVCHKGMDGADV..QDISSELSDEIRRLPEKIE................
A5AV28_VITVI/23-72 ...gmkqmfdpf---------ER----VAR..AHH..VCPCCERPFSAEEE..DEFVKKQRVKAASSAEHMK................
A7TF44_VANPO/658-712 ............KMHQTTLAFNKKALEIAE..NNN..CCYLCSRAFDDESF.kSSLLNQLKERTNDEFEV--tl..............
H2L8A9_ORYLA/658-713 ............MLAGATAVYTQFISQLTE..ERE.pCCPVCQRTFPSESD.lQDVINDMQSKLRLVPDKLK................
F1NX91_CHICK/659-713 ............-LAGATAVYSQFITQLTE..ENQ.sCCPVCQRVFQTEAE.lQDVISDLQSKLRLAPDKLK................
C9R960_AMMDK/396-435 ...........a-LNLEAERYRRALSSLQ-..---..RCPLCGTDLTPEHV..EKV----------------wrqele..........
F9N0B3_PEPMA/352-395 .....eenskef------------------..-NEslNCPVCGKEFDEDKK..NEIIANFN-----------knkaeklaeie.....
D9TLN7_THETC/408-460 ..........cn---DRINELKENYNTILK..TDA..KCPLCNSPLDQDKK..SSLLGDFKEKINGYKKEI-s...............
#=GC SS_cons ............HHHHHHHHHHHHHHHHTT..-SE..E-TTT--EE-HHHH..HHHHHHHHHHHHHHHH---HHH.............
#=GC seq_cons .............htttht.hpphlppLsc..ppt..sCPlCpRshss-pc..pcllpchpsclcth.cp..................
//
