GenomeNet

Database: Pfam
Entry: RepB-RCR_reg
LinkDB: RepB-RCR_reg
Original site: RepB-RCR_reg 
#=GF ID   RepB-RCR_reg
#=GF AC   PF10723.6
#=GF DE   Replication regulatory protein RepB
#=GF AU   Mistry J, Coggill P
#=GF SE   PRODOM_PD763888
#=GF GA   20.90 20.90;
#=GF TC   21.10 21.00;
#=GF NC   20.60 20.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   9409148
#=GF RT   Rolling-circle replication of bacterial plasmids. 
#=GF RA   Khan SA; 
#=GF RL   Microbiol Mol Biol Rev. 1997;61:442-455.
#=GF DR   INTERPRO; IPR019661;
#=GF CC   This is a family of proteins which regulate replication of
#=GF CC   rolling circle replication (RCR) plasmids that have a
#=GF CC   double-strand replication origin (dso). Regulation of
#=GF CC   replication of RCR plasmids occurs mainly at initiation of
#=GF CC   leading strand synthesis at the dso, such that Rep protein
#=GF CC   concentration controls plasmid replication [1].
#=GF SQ   15
#=GS W8VCH7_YEREN/5-74    AC W8VCH7.1
#=GS A6TI22_KLEP7/1-83    AC A6TI22.1
#=GS A8H1Z2_SHEPA/59-137  AC A8H1Z2.1
#=GS Q93GS8_SALTY/8-88    AC Q93GS8.1
#=GS D5X772_THIK1/15-89   AC D5X772.1
#=GS A0KKI4_AERHH/6-74    AC A0KKI4.1
#=GS Q7ARH5_YERPE/1-82    AC Q7ARH5.1
#=GS C4IEW2_CLOBU/1-54    AC C4IEW2.1
#=GS Q326V9_SHIDS/1-83    AC Q326V9.1
#=GS Q326M6_SHIDS/1-81    AC Q326M6.1
#=GS R6T165_9FIRM/3-61    AC R6T165.1
#=GS F7V1X3_CLOSS/1-49    AC F7V1X3.1
#=GS D2TV77_CITRI/1-83    AC D2TV77.1
#=GS W8U9R8_YEREN/1-81    AC W8U9R8.1
#=GS B2VB58_ERWT9/1-77    AC B2VB58.1
W8VCH7_YEREN/5-74               ................vherkrrp------------..-----KGPQKSNASYQRDFWERRKL.THS.....RIVMVVPNEVKEDLELLSSVYGKTKTEVIEQLIKM------akdg.......
A6TI22_KLEP7/1-83               ........................MSRSADKTTSSTnaKRAYRKGKPMSASERQLAAIARKRE.THK.....EVKVFVKNPLKDVMIAVCEEEGLTQAQFIEKLLERELTE--rg.........
A8H1Z2_SHEPA/59-137             qtsnssveatvfiksfagnmykah------------..--------------KA--RLYRKKLgAKK.....MLNVAITPKHMQNLEYICKSQGMQKNKVIEMMIEGSLQH--lin........
Q93GS8_SALTY/8-88               ........................MSQIENAVTSSS..KRIYRKGNPLSSAEKKRLSISRKKT.THK.....ELNVFIQNIHKESLQQLCEETGTTQAQMIELLIEREMAKR-a..........
D5X772_THIK1/15-89              ..............pgrprkgeer------------..-------EPLSDAERARRYAARKRA.KARnaalvAVTVYLSPQATDRLTELGIRRQATRAEVLEKLILQ------adpf.......
A0KKI4_AERHH/6-74               .................kvssaqd------------..-----------NAERQRQHVKRKQE.THS.....RLQCWISNRHAERLAMLGLQLEDSQASLIEQAID-------llyqheleqkq
Q7ARH5_YERPE/1-82               ........................MSQIENAVTSSS..KRAYRKGNPLTGAEKQRMSVSRKKE.THK.....AINVFIQNDLKNELLQLCEDSGLTQTEMIERWIQREKAAR-tn.........
C4IEW2_CLOBU/1-54               .......................m------------..--------------------ARQKK.DGV.....YINYYIRKDIKEKLDEYCEEVGQTNTLALERILGQ------fldkyfeekk.
Q326V9_SHIDS/1-83               ........................MSQTENAVTSSLsqKRFVRRGKPMTDSEKQMAAVARKRL.THK.....EIKVFVKNPLKDLMVEYCEREGITQAQFVEKIIKDELQRL-d..........
Q326M6_SHIDS/1-81               ........................MSQIENAVTSSP..KRIYRKGNPLTGAEKQRISVSRKKG.THK.....AINVFIQSELKDDLTQLCKDSGLTQKEMIEHWILKEKAA--vd.........
R6T165_9FIRM/3-61               ..........ytkasnkavqkysa------------..------------------------K.TYD.....QIKVLVKKGEREEIKNYAESQGMSLNGYINKLIKDDMK---tad........
F7V1X3_CLOSS/1-49               ....................mprp------------..-----------------------KK.DAH.....VLNIKLESSVYEDLDRFCEETGVTKTAAVEKILRS------flddy......
D2TV77_CITRI/1-83               ........................MSQTENAVTSSSgaKRAYRKGNPLSDAEKQRLSVARKRA.SFK.....EVKVFLEPKYKAMLMQMCHEDGLTQAEVLTALIKSEAQKR-c..........
W8U9R8_YEREN/1-81               ........................MSQIENAVTSSS..KRTYRKGNPLSEADRQKIASARKRA.THK.....ELKVFIKPEIKEYLSNLCEEDGVTQAEVLEKLIEREAF---srk........
B2VB58_ERWT9/1-77               ..........mpqtdnptqsevnp------------..---SRK-APLTARERKMRSVARKRE.THS.....PLNVFIHNSTKQKLDEMCKKSGLTQAEAIEHLIK-------gmnsv......
#=GC seq_cons                   ...........................................+.tPhosuE+phhtluRK+t.TH+.....tlsValpsphK-cLpplCccpGhTQsphIE+lIcpph....sh.........
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