GenomeNet

Database: Pfam
Entry: RepB-RCR_reg
LinkDB: RepB-RCR_reg
Original site: RepB-RCR_reg 
#=GF ID   RepB-RCR_reg
#=GF AC   PF10723.7
#=GF DE   Replication regulatory protein RepB
#=GF AU   Mistry J, Coggill P
#=GF SE   PRODOM_PD763888
#=GF GA   20.90 20.90;
#=GF TC   21.10 21.00;
#=GF NC   20.60 20.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   9409148
#=GF RT   Rolling-circle replication of bacterial plasmids. 
#=GF RA   Khan SA; 
#=GF RL   Microbiol Mol Biol Rev. 1997;61:442-455.
#=GF DR   INTERPRO; IPR019661;
#=GF CC   This is a family of proteins which regulate replication of
#=GF CC   rolling circle replication (RCR) plasmids that have a
#=GF CC   double-strand replication origin (dso). Regulation of
#=GF CC   replication of RCR plasmids occurs mainly at initiation of
#=GF CC   leading strand synthesis at the dso, such that Rep protein
#=GF CC   concentration controls plasmid replication [1].
#=GF SQ   23
#=GS W8VCH7_YEREN/5-74      AC W8VCH7.1
#=GS A6TI22_KLEP7/1-83      AC A6TI22.1
#=GS A8H1Z2_SHEPA/59-137    AC A8H1Z2.1
#=GS Q93GS8_SALTY/8-88      AC Q93GS8.1
#=GS D5X772_THIK1/15-89     AC D5X772.1
#=GS A0A0M2KAP0_9ENTR/1-79  AC A0A0M2KAP0.1
#=GS Q7ARH5_YERPE/1-82      AC Q7ARH5.1
#=GS A0KKI4_AERHH/6-74      AC A0KKI4.1
#=GS G2H038_9ENTR/2-77      AC G2H038.1
#=GS C4IEW2_CLOBU/1-54      AC C4IEW2.1
#=GS F0IHS3_9FLAO/36-96     AC F0IHS3.1
#=GS A0A0G3Q3B1_KLUIN/1-70  AC A0A0G3Q3B1.1
#=GS A0A0M2KAN3_9ENTR/1-84  AC A0A0M2KAN3.1
#=GS A0A0G3Q732_KLUIN/1-60  AC A0A0G3Q732.1
#=GS A0A0M2K4K4_9ENTR/1-78  AC A0A0M2K4K4.1
#=GS Q326V9_SHIDS/1-83      AC Q326V9.1
#=GS Q326M6_SHIDS/1-81      AC Q326M6.1
#=GS R6T165_9FIRM/3-61      AC R6T165.1
#=GS F7V1X3_CLOSS/1-49      AC F7V1X3.1
#=GS G2H1Q1_9ENTR/3-77      AC G2H1Q1.1
#=GS D2TV77_CITRI/1-83      AC D2TV77.1
#=GS W8U9R8_YEREN/1-81      AC W8U9R8.1
#=GS B2VB58_ERWT9/1-77      AC B2VB58.1
W8VCH7_YEREN/5-74                 ................vherkrrp------------..-----KGPQKSNASYQRDFWERRKL.THS.....RIVMVVPNEVKEDLELLSSVYGKTKTEVIEQLIKM------akdg.......
A6TI22_KLEP7/1-83                 ........................MSRSADKTTSSTnaKRAYRKGKPMSASERQLAAIARKRE.THK.....EVKVFVKNPLKDVMIAVCEEEGLTQAQFIEKLLERELTE--rg.........
A8H1Z2_SHEPA/59-137               qtsnssveatvfiksfagnmykah------------..--------------KA--RLYRKKLgAKK.....MLNVAITPKHMQNLEYICKSQGMQKNKVIEMMIEGSLQH--lin........
Q93GS8_SALTY/8-88                 ........................MSQIENAVTSSS..KRIYRKGNPLSSAEKKRLSISRKKT.THK.....ELNVFIQNIHKESLQQLCEETGTTQAQMIELLIEREMAKR-a..........
D5X772_THIK1/15-89                ..............pgrprkgeer------------..-------EPLSDAERARRYAARKRA.KARnaalvAVTVYLSPQATDRLTELGIRRQATRAEVLEKLILQ------adpf.......
A0A0M2KAP0_9ENTR/1-79             ........................MSQAVNAATSSS..KRAYRKGNPLSVSERQQALMERRKE.THK.....EIKVYVPTVLKERLQNLCEAEGVSQAEMISRLIAD------agip.......
Q7ARH5_YERPE/1-82                 ........................MSQIENAVTSSS..KRAYRKGNPLTGAEKQRMSVSRKKE.THK.....AINVFIQNDLKNELLQLCEDSGLTQTEMIERWIQREKAAR-tn.........
A0KKI4_AERHH/6-74                 .................kvssaqd------------..-----------NAERQRQHVKRKQE.THS.....RLQCWISNRHAERLAMLGLQLEDSQASLIEQAID-------llyqheleqkq
G2H038_9ENTR/2-77                 ..................teqnek-----------K..KREYRLGNPLTLTEYTNRYRDRKKE.NNR.....EMRLFIPIDLGNRFTEHCREIGKSRSEIVSNLIEDYIQ---svc........
C4IEW2_CLOBU/1-54                 .......................m------------..--------------------ARQKK.DGV.....YINYYIRKDIKEKLDEYCEEVGQTNTLALERILGQ------fldkyfeekk.
F0IHS3_9FLAO/36-96                ..................ymylck------------..--------------KINRSMARERI.KGK.....ALNIRVSEEFITLLKLLSEKKGMSQANLIEYLVRKEADA--iq.........
A0A0G3Q3B1_KLUIN/1-70             .....................msr------------..--VVERQVHKSNLDKQKDYRNRIRD.THD.....QLNLYLPKDAKRMLIEITKVKKLTQAEVIEFLVKS------yydglk.....
A0A0M2KAN3_9ENTR/1-84             ........................MSQATNAATSSSkeKRAYRKGNPMSATERQLAAIARKRE.THK.....EVNVFIRNPMKAQLLHLCKQEGLTQGEMIEKLIQIETKRR-ge.........
A0A0G3Q732_KLUIN/1-60             ........................------------..---------MSASEKQQAAVARKKL.THK.....ELKIYLRNAIKDRLVVECEKAGLTQAEYIERLLQQA-----fdeld......
A0A0M2K4K4_9ENTR/1-78             .......maedegavrgtkvgrpr------------..-------KYETKSDKQRAYITQKLQ.TKV.....QTKVLLSPDGRDTLNKLCKLRGVTQGELVTELIKKY-----asev.......
Q326V9_SHIDS/1-83                 ........................MSQTENAVTSSLsqKRFVRRGKPMTDSEKQMAAVARKRL.THK.....EIKVFVKNPLKDLMVEYCEREGITQAQFVEKIIKDELQRL-d..........
Q326M6_SHIDS/1-81                 ........................MSQIENAVTSSP..KRIYRKGNPLTGAEKQRISVSRKKG.THK.....AINVFIQSELKDDLTQLCKDSGLTQKEMIEHWILKEKAA--vd.........
R6T165_9FIRM/3-61                 ..........ytkasnkavqkysa------------..------------------------K.TYD.....QIKVLVKKGEREEIKNYAESQGMSLNGYINKLIKDDMK---tad........
F7V1X3_CLOSS/1-49                 ....................mprp------------..-----------------------KK.DAH.....VLNIKLESSVYEDLDRFCEETGVTKTAAVEKILRS------flddy......
G2H1Q1_9ENTR/3-77                 ..................eqnekk-----------P..KREYRKGNPLTLTERTKRYKDKQKK.NNR.....EMRLFIPTDLGNQFTDHCREIKKSRSEVVSKLIEDY-----iksv.......
D2TV77_CITRI/1-83                 ........................MSQTENAVTSSSgaKRAYRKGNPLSDAEKQRLSVARKRA.SFK.....EVKVFLEPKYKAMLMQMCHEDGLTQAEVLTALIKSEAQKR-c..........
W8U9R8_YEREN/1-81                 ........................MSQIENAVTSSS..KRTYRKGNPLSEADRQKIASARKRA.THK.....ELKVFIKPEIKEYLSNLCEEDGVTQAEVLEKLIEREAF---srk........
B2VB58_ERWT9/1-77                 ..........mpqtdnptqsevnp------------..---SRK-APLTARERKMRSVARKRE.THS.....PLNVFIHNSTKQKLDEMCKKSGLTQAEAIEHLIK-------gmnsv......
#=GC seq_cons                     ...........................................h.t.hossE+ppthhsRK+p.T++.....plpValpsshK-pLpplCccpGhTQuEhIE+LIcp......s..........
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