#=GF ID Rhomboid
#=GF AC PF01694.17
#=GF DE Rhomboid family
#=GF AU Sohrmann M, Bateman A
#=GF SE Pfam-B_1399 (release 4.1)
#=GF GA 21.90 21.90;
#=GF TC 21.90 21.90;
#=GF NC 21.80 21.80;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF WK Rhomboid_protease
#=GF RN [1]
#=GF RM 2110920
#=GF RT rhomboid, a gene required for dorsoventral axis establishment
#=GF RT and peripheral nervous system development in Drosophila
#=GF RT melanogaster.
#=GF RA Bier E, Jan LY, Jan YN;
#=GF RL Genes Dev 1990;4:190-203.
#=GF RN [2]
#=GF RM 11672525
#=GF RT Drosophila rhomboid-1 defines a family of putative intramembrane
#=GF RT serine proteases.
#=GF RA Urban S, Lee JR, Freeman M;
#=GF RL Cell 2001;107:173-182.
#=GF RN [3]
#=GF RM 12620104
#=GF RT The rhomboids: a nearly ubiquitous family of intramembrane
#=GF RT serine proteases that probably evolved by multiple ancient
#=GF RT horizontal gene transfers.
#=GF RA Koonin EV, Makarova KS, Rogozin IB, Davidovic L, Letellier MC,
#=GF RA Pellegrini L;
#=GF RL Genome Biol 2003;4:R19.
#=GF RN [4]
#=GF RM 15684070
#=GF RT Reconstitution of intramembrane proteolysis in vitro reveals
#=GF RT that pure rhomboid is sufficient for catalysis and specificity.
#=GF RA Urban S, Wolfe MS;
#=GF RL Proc Natl Acad Sci U S A. 2005;102:1883-1888.
#=GF RN [5]
#=GF RM 15753289
#=GF RT A spatially localized rhomboid protease cleaves cell surface
#=GF RT adhesins essential for invasion by Toxoplasma.
#=GF RA Brossier F, Jewett TJ, Sibley LD, Urban S;
#=GF RL Proc Natl Acad Sci U S A. 2005;102:4146-4151.
#=GF DR INTERPRO; IPR022764;
#=GF DR MEROPS; S54;
#=GF DR MEROPS; S54;
#=GF CC This family contains integral membrane proteins that are related
#=GF CC to Drosophila rhomboid protein Swiss:P20350. Members of this
#=GF CC family are found in bacteria and eukaryotes.
#=GF CC Rhomboid promotes the cleavage of the membrane-anchored
#=GF CC TGF-alpha-like growth factor Spitz, allowing it to activate the
#=GF CC Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is
#=GF CC an intramembrane serine protease [2][3][4] (EC:3.4.21.105).
#=GF CC Parasite-encoded rhomboid enzymes are also important for
#=GF CC invasion of host cells by Toxoplasma and the malaria parasite
#=GF CC [5].
#=GF SQ 7854
#=GS E2IBT5_MYCSM/78-230 AC E2IBT5.1
#=GS D4UX74_ENTFL/56-201 AC D4UX74.1
#=GS F1UCS0_PROAA/31-173 AC F1UCS0.1
#=GS Q02C85_SOLUE/102-245 AC Q02C85.1
#=GS D9X065_STRVR/126-266 AC D9X065.1
#=GS F9P1T8_STRMT/52-195 AC F9P1T8.1
#=GS E0TFK9_PARBH/66-236 AC E0TFK9.1
#=GS H0K284_9PSEU/45-185 AC H0K284.1
#=GS C7NYQ6_HALMD/88-257 AC C7NYQ6.1
#=GS F1L8L5_ASCSU/162-314 AC F1L8L5.1
#=GS B5RW26_RALSL/24-184 AC B5RW26.1
#=GS D6X9J9_STRPR/129-268 AC D6X9J9.1
#=GS Q2SGR5_HAHCH/57-205 AC Q2SGR5.1
#=GS H8I6E2_METCZ/106-253 AC H8I6E2.1
#=GS G8V633_STAAU/196-338 AC G8V633.1
#=GS F2LQC5_BURGS/56-202 AC F2LQC5.1
#=GS F0PDH7_ENTF6/56-201 AC F0PDH7.1
#=GS RHDF1_BOVIN/648-792 AC A7YWH9.1
#=GS C9K011_HUMAN/59-151 AC C9K011.1
#=GS F8EXY3_SPICH/48-186 AC F8EXY3.1
#=GS F4PH58_DICFS/163-311 AC F4PH58.1
#=GS G2YWQ3_BOTF4/188-346 AC G2YWQ3.1
#=GS E9QI41_DANRE/55-205 AC E9QI41.1
#=GS H1BLK0_9FIRM/205-347 AC H1BLK0.1
#=GS A6X099_OCHA4/52-218 AC A6X099.1
#=GS C5EMC1_9FIRM/50-197 AC C5EMC1.1
#=GS G2CRG4_ECOLX/129-273 AC G2CRG4.1
#=GS A2TVT1_9FLAO/72-214 AC A2TVT1.2
#=GS E8LK54_9GAMM/139-282 AC E8LK54.1
#=GS Q3IHW2_PSEHT/126-269 AC Q3IHW2.1
#=GS G7IAP6_MEDTR/104-248 AC G7IAP6.1
#=GS F5YX71_MYCSD/28-180 AC F5YX71.1
#=GS H4E863_STAAU/196-338 AC H4E863.1
#=GS F1XGR6_MORCA/34-187 AC F1XGR6.1
#=GS D1WN82_STAEP/196-339 AC D1WN82.1
#=GS F2U1B8_SALS5/1292-1436 AC F2U1B8.1
#=GS D4BLK3_BIFBR/58-206 AC D4BLK3.1
#=GS G1SU02_RABIT/199-351 AC G1SU02.1
#=GS D6SX27_GARVA/58-202 AC D6SX27.1
#=GS A7ZJ48_ECO24/55-203 AC A7ZJ48.1
#=GS F7EP89_MACMU/209-366 AC F7EP89.1
#=GS F9BMU4_VIBCL/32-179 AC F9BMU4.1
#=GS E4NRZ8_HALBP/119-282 AC E4NRZ8.1
#=GS E4ATN6_PROAA/28-165 AC E4ATN6.1
#=GS A3VHY2_9RHOB/71-219 AC A3VHY2.1
#=GS B8ANI8_ORYSI/58-215 AC B8ANI8.1
#=GS E4RRA7_LEAB4/50-218 AC E4RRA7.1
#=GS B5JEP0_9BACT/121-270 AC B5JEP0.1
#=GS D2TLL5_CITRI/129-272 AC D2TLL5.1
#=GS G7GQ63_9ACTO/114-253 AC G7GQ63.1
#=GS H2BSB9_9FLAO/49-200 AC H2BSB9.1
#=GS A5K2J0_PLAVS/158-333 AC A5K2J0.1
#=GS A4YCC7_SHEPC/134-278 AC A4YCC7.1
#=GS A3RNM9_RALSL/247-395 AC A3RNM9.1
#=GS E4GH99_PROAA/28-165 AC E4GH99.1
#=GS A6BVZ7_YERPE/130-274 AC A6BVZ7.1
#=GS C0G6Y8_9RHIZ/78-245 AC C0G6Y8.1
#=GS G5VF86_ECOLX/129-273 AC G5VF86.1
#=GS A0JU40_ARTS2/45-189 AC A0JU40.1
#=GS H8J003_MYCIT/54-206 AC H8J003.1
#=GS D8RJR1_SELML/58-215 AC D8RJR1.1
#=GS H5LY49_ECOLX/55-205 AC H5LY49.1
#=GS C7NNV9_HALUD/45-196 AC C7NNV9.1
#=GS PARL_RAT/199-351 AC Q3B8P0.1
#=GS C5Q9H2_STAEP/196-339 AC C5Q9H2.1
#=GS Q2Y670_NITMU/57-205 AC Q2Y670.1
#=GS F1TXQ3_PROAA/31-173 AC F1TXQ3.1
#=GS H8W8N5_MARHY/191-345 AC H8W8N5.1
#=GS C8V7J1_EMENI/60-209 AC C8V7J1.1
#=GS H2R3M9_PANTR/59-213 AC H2R3M9.1
#=GS B4P5R1_DROYA/179-332 AC B4P5R1.1
#=GS I0CRC2_LISMN/221-363 AC I0CRC2.1
#=GS C4JUM5_UNCRE/226-371 AC C4JUM5.1
#=GS E8RQV7_ASTEC/50-206 AC E8RQV7.1
#=GS E7ZWN9_SALMO/127-271 AC E7ZWN9.1
#=GS F2U9E3_SALS5/174-356 AC F2U9E3.1
#=GS F0RZL7_SPHGB/52-204 AC F0RZL7.1
#=GS G5XNI9_ECOLX/55-205 AC G5XNI9.1
#=GS D2T9D2_ERWP6/127-270 AC D2T9D2.1
#=GS GLPG_ECO27/129-273 AC B7UKC8.1
#=GS E4FQX1_PROAA/31-173 AC E4FQX1.1
#=GS D7CJX5_SYNLT/49-212 AC D7CJX5.1
#=GS B0G939_9FIRM/48-195 AC B0G939.1
#=GS Q7CSV4_AGRT5/69-221 AC Q7CSV4.2
#=GS B5JER5_9BACT/11-213 AC B5JER5.1
#=GS C1DXA1_SULAA/53-213 AC C1DXA1.1
#=GS Q5MZS1_SYNP6/54-198 AC Q5MZS1.1
#=GS I1HAI3_BRADI/113-257 AC I1HAI3.1
#=GS F2N0Q3_PSEU6/132-282 AC F2N0Q3.1
#=GS F6VHH2_CALJA/44-187 AC F6VHH2.1
#=GS Q3ANU3_CHLCH/39-193 AC Q3ANU3.1
#=GS B4SPU6_STRM5/36-190 AC B4SPU6.1
#=GS B3T2K6_9ZZZZ/63-215 AC B3T2K6.1
#=GS C4WXA5_ACYPI/150-222 AC C4WXA5.1
#=GS H5MLM2_ECOLX/129-273 AC H5MLM2.1
#=GS E9EW46_METAR/376-532 AC E9EW46.1
#=GS H3LUU9_KLEOX/127-271 AC H3LUU9.1
#=GS B6W485_9BACE/43-188 AC B6W485.1
#=GS D8NDM1_RALSL/39-194 AC D8NDM1.1
#=GS E7MUL7_STAAU/196-338 AC E7MUL7.1
#=GS Q4RFU7_TETNG/60-237 AC Q4RFU7.1
#=GS E8R2F7_ISOPI/138-287 AC E8R2F7.1
#=GS F2CP30_STRSA/52-194 AC F2CP30.1
#=GS G4AH59_AGGAC/1-105 AC G4AH59.1
#=GS E4GBP8_PROAA/31-173 AC E4GBP8.1
#=GS G8UDI5_BACCE/41-185 AC G8UDI5.1
#=GS H9HAD0_ATTCE/64-218 AC H9HAD0.1
#=GS E6EAV4_PROAA/31-173 AC E6EAV4.1
#=GS G7THZ0_9XANT/62-220 AC G7THZ0.1
#=GS F2KMK1_ARCVS/109-258 AC F2KMK1.1
#=GS H7Y0F5_CAMJU/30-170 AC H7Y0F5.1
#=GS B4M210_DROVI/229-290 AC B4M210.1
#=GS G8BWE8_TETPH/47-198 AC G8BWE8.1
#=GS H7LHW5_STRPN/52-195 AC H7LHW5.1
#=GS Q29FG6_DROPS/263-433 AC Q29FG6.1
#=GS B6KVS8_TOXGO/103-251 AC B6KVS8.1
#=GS B8FAS8_DESAA/57-204 AC B8FAS8.1
#=GS B5RYC9_RALSL/136-284 AC B5RYC9.1
#=GS G7TD14_9XANT/54-198 AC G7TD14.1
#=GS F7YYK2_9THEM/47-193 AC F7YYK2.1
#=GS E2QFS2_ECOLX/129-273 AC E2QFS2.1
#=GS H1GYG6_9FLAO/37-189 AC H1GYG6.1
#=GS A0PZ45_CLONN/63-202 AC A0PZ45.1
#=GS F1U5B6_PROAA/31-173 AC F1U5B6.1
#=GS B9LKJ4_CHLSY/86-232 AC B9LKJ4.1
#=GS G0JV27_STEMA/36-190 AC G0JV27.1
#=GS C5GAE7_AJEDR/386-550 AC C5GAE7.1
#=GS Q2S4Q9_SALRD/85-233 AC Q2S4Q9.1
#=GS F2ID87_FLUTR/54-146 AC F2ID87.1
#=GS B3MRK0_DROAN/227-378 AC B3MRK0.1
#=GS D2MTB5_CAMJU/30-166 AC D2MTB5.1
#=GS G5JWC6_9STRE/50-193 AC G5JWC6.1
#=GS A3HXT0_9BACT/65-221 AC A3HXT0.1
#=GS A3W1X5_9RHOB/70-219 AC A3W1X5.1
#=GS B9GJM5_POPTR/108-252 AC B9GJM5.1
#=GS C2JI37_VIBCL/132-275 AC C2JI37.1
#=GS G5EP24_9MICC/113-256 AC G5EP24.1
#=GS E4M309_9FIRM/65-226 AC E4M309.1
#=GS D2RCL9_GARV4/58-202 AC D2RCL9.1
#=GS C4FT22_9FIRM/56-201 AC C4FT22.1
#=GS B1VGX2_CORU7/35-179 AC B1VGX2.1
#=GS E7KJ66_YEASA/1-112 AC E7KJ66.1
#=GS G4CEF3_9CLOT/186-329 AC G4CEF3.1
#=GS D3SLU3_THEAH/54-216 AC D3SLU3.1
#=GS B5JNE9_9BACT/70-214 AC B5JNE9.1
#=GS I1NGR1_SOYBN/110-254 AC I1NGR1.1
#=GS A5E1V0_LODEL/404-555 AC A5E1V0.1
#=GS D4VAP0_BACVU/61-217 AC D4VAP0.1
#=GS E5CMB7_STAHO/195-340 AC E5CMB7.1
#=GS I0N5W2_STRPN/52-195 AC I0N5W2.1
#=GS GLPG_ECOHS/129-273 AC A8A5N2.1
#=GS B7H4N9_BACC4/41-185 AC B7H4N9.1
#=GS H4PQC3_ECOLX/129-273 AC H4PQC3.1
#=GS H3HNG2_STRPU/406-559 AC H3HNG2.1
#=GS E7NQ34_TREPH/47-200 AC E7NQ34.1
#=GS E3PLM9_ECOH1/129-273 AC E3PLM9.1
#=GS H7ZF09_CAMJU/33-173 AC H7ZF09.1
#=GS A8J9Z0_CHLRE/46-178 AC A8J9Z0.1
#=GS C8MZZ6_STAAU/196-338 AC C8MZZ6.1
#=GS A3U475_9RHOB/46-189 AC A3U475.1
#=GS D4G5D9_BACNA/52-196 AC D4G5D9.1
#=GS H2QA79_PANTR/239-396 AC H2QA79.1
#=GS H2H388_CORDP/40-181 AC H2H388.1
#=GS F9IH72_ACIBA/39-192 AC F9IH72.1
#=GS D2QZE4_PIRSD/87-240 AC D2QZE4.1
#=GS H1Y0L7_9SPHI/64-220 AC H1Y0L7.1
#=GS E8QWK9_ISOPI/335-480 AC E8QWK9.1
#=GS H5Q574_ECOLX/129-273 AC H5Q574.1
#=GS H0FQ56_BACAM/52-196 AC H0FQ56.1
#=GS C6TJI4_SOYBN/69-223 AC C6TJI4.1
#=GS B9XMW1_9BACT/61-207 AC B9XMW1.1
#=GS H0Y3I5_HUMAN/594-682 AC H0Y3I5.1
#=GS H3S7M0_STAAU/196-338 AC H3S7M0.1
#=GS A9CIP3_AGRT5/75-245 AC A9CIP3.1
#=GS A3H592_VIBCL/132-233 AC A3H592.1
#=GS B1RPS6_CLOPF/197-338 AC B1RPS6.1
#=GS E0VDE0_PEDHC/64-218 AC E0VDE0.1
#=GS H7IGP6_STRPN/52-195 AC H7IGP6.1
#=GS E6AWH7_ECOLX/129-273 AC E6AWH7.1
#=GS H1I7R2_9BACI/221-363 AC H1I7R2.1
#=GS F6BRU2_SINMB/70-221 AC F6BRU2.1
#=GS E8PNB4_THESS/52-208 AC E8PNB4.1
#=GS G6RIL2_STRPN/52-101 AC G6RIL2.1
#=GS I1PTF0_ORYGL/109-258 AC I1PTF0.1
#=GS A5UHM0_HAEIG/44-188 AC A5UHM0.1
#=GS G5EWC8_9ACTO/123-270 AC G5EWC8.1
#=GS H9J020_BOMMO/132-294 AC H9J020.1
#=GS Q4RLF4_TETNG/689-842 AC Q4RLF4.1
#=GS E0J1U0_ECOLW/55-205 AC E0J1U0.1
#=GS G3IUH4_9GAMM/62-222 AC G3IUH4.1
#=GS C0WU26_LACBU/61-204 AC C0WU26.1
#=GS F3LA61_STRPO/51-194 AC F3LA61.1
#=GS Q0AVB1_SYNWW/58-217 AC Q0AVB1.1
#=GS H1X8M7_LACCO/54-199 AC H1X8M7.1
#=GS B8L6V0_9GAMM/50-204 AC B8L6V0.1
#=GS B4H2T4_DROPE/226-377 AC B4H2T4.1
#=GS Q24X28_DESHY/187-327 AC Q24X28.1
#=GS Q8YQA2_NOSS1/55-222 AC Q8YQA2.1
#=GS F0VU14_STRG2/51-193 AC F0VU14.1
#=GS E2TXF7_MYCTU/71-223 AC E2TXF7.1
#=GS F4SVH6_ECOLX/55-205 AC F4SVH6.1
#=GS B9S031_RICCO/68-221 AC B9S031.1
#=GS E5WAP0_9BACI/52-196 AC E5WAP0.1
#=GS I1MS13_SOYBN/80-234 AC I1MS13.1
#=GS H3PJU4_BRUAO/67-234 AC H3PJU4.1
#=GS C7TG75_LACRL/54-215 AC C7TG75.1
#=GS A1VEX0_DESVV/66-224 AC A1VEX0.1
#=GS E6TV38_BACCJ/53-197 AC E6TV38.1
#=GS E1J1Y0_ECOLX/129-273 AC E1J1Y0.1
#=GS D4HD68_PROAS/32-174 AC D4HD68.1
#=GS H2CII1_9LEPT/46-195 AC H2CII1.1
#=GS G6CV65_DANPL/567-711 AC G6CV65.1
#=GS B4HVT4_DROSE/153-309 AC B4HVT4.1
#=GS E8WGE7_STRFA/82-239 AC E8WGE7.1
#=GS G1WDT3_9BACT/48-229 AC G1WDT3.1
#=GS H7V6C8_CAMCO/30-172 AC H7V6C8.1
#=GS G2SFN6_RHOMR/60-211 AC G2SFN6.1
#=GS D1BI17_SANKS/113-257 AC D1BI17.1
#=GS H2W847_CAEJA/848-992 AC H2W847.1
#=GS G6ZAA2_VIBCL/132-275 AC G6ZAA2.1
#=GS H8AJ47_CAMJU/30-170 AC H8AJ47.1
#=GS I0DXI0_PROST/62-229 AC I0DXI0.1
#=GS Q8PMH7_XANAC/56-211 AC Q8PMH7.1
#=GS E4TA76_RIEAD/40-241 AC E4TA76.1
#=GS B0DIF5_LACBS/217-262 AC B0DIF5.1
#=GS B9I4A7_POPTR/82-226 AC B9I4A7.1
#=GS G7YES2_CLOSI/13-168 AC G7YES2.1
#=GS Q166M6_ROSDO/55-215 AC Q166M6.1
#=GS D6H0B8_STAAU/196-338 AC D6H0B8.1
#=GS B9ID63_POPTR/113-257 AC B9ID63.1
#=GS B0SQV8_LEPBP/41-193 AC B0SQV8.1
#=GS A4A7W5_9GAMM/130-279 AC A4A7W5.1
#=GS F1U270_PROAA/43-190 AC F1U270.1
#=GS C6YDF7_VIBCL/71-218 AC C6YDF7.1
#=GS Q7RP93_PLAYO/162-332 AC Q7RP93.1
#=GS F7ZP42_CLOAT/183-326 AC F7ZP42.1
#=GS E4EP47_PROAA/28-165 AC E4EP47.1
#=GS E6JYP9_PARDN/85-232 AC E6JYP9.1
#=GS G2G2V5_9CLOT/50-195 AC G2G2V5.1
#=GS E3RSA5_PYRTT/262-407 AC E3RSA5.1
#=GS B7FVB4_PHATC/1-141 AC B7FVB4.1
#=GS E6X2F3_NITSE/50-196 AC E6X2F3.1
#=GS A1S0S3_THEPD/59-221 AC A1S0S3.1
#=GS B0W246_CULQU/180-332 AC B0W246.1
#=GS B3WJA5_ECOLX/127-271 AC B3WJA5.1
#=GS B7GSM4_BIFLS/92-240 AC B7GSM4.1
#=GS C6Y012_PEDHD/67-223 AC C6Y012.1
#=GS F1VEH1_PROAA/28-165 AC F1VEH1.1
#=GS G6T6M7_STRPN/52-195 AC G6T6M7.1
#=GS E4YHI3_OIKDI/134-287 AC E4YHI3.1
#=GS F2BP95_STRSA/52-193 AC F2BP95.1
#=GS E4DCD0_PROAA/28-165 AC E4DCD0.1
#=GS A5CYS6_PELTS/24-185 AC A5CYS6.1
#=GS B0XQ37_ASPFC/393-553 AC B0XQ37.1
#=GS A3J8F5_9ALTE/150-307 AC A3J8F5.1
#=GS F3K576_PSESZ/38-179 AC F3K576.1
#=GS A7AWM4_BABBO/304-423 AC A7AWM4.1
#=GS G2ALP4_ECOLX/129-273 AC G2ALP4.1
#=GS H7LVR8_STRPN/52-195 AC H7LVR8.1
#=GS C6RF18_9PROT/36-176 AC C6RF18.1
#=GS F9J9V9_ACIBA/35-186 AC F9J9V9.1
#=GS A8HNC7_CHLRE/56-211 AC A8HNC7.1
#=GS A5FMX7_FLAJ1/45-187 AC A5FMX7.1
#=GS C5R8K7_WEIPA/53-197 AC C5R8K7.1
#=GS H4LI97_ECOLX/127-271 AC H4LI97.1
#=GS F7A3I8_ORNAN/647-716 AC F7A3I8.1
#=GS C0GDH9_9FIRM/60-220 AC C0GDH9.1
#=GS B1QFY6_CLOBO/196-338 AC B1QFY6.1
#=GS F0BQH1_9XANT/44-202 AC F0BQH1.1
#=GS B2KHV7_RHIFE/648-792 AC B2KHV7.1
#=GS F6D156_MARPP/136-284 AC F6D156.1
#=GS H2QDY1_PANTR/648-792 AC H2QDY1.1
#=GS C3QNZ5_9BACE/195-339 AC C3QNZ5.1
#=GS B4DFK3_HUMAN/174-269 AC B4DFK3.1
#=GS A8YNC2_MICAE/43-189 AC A8YNC2.1
#=GS F7ZL19_ROSLO/55-215 AC F7ZL19.1
#=GS B8BCK3_ORYSI/177-321 AC B8BCK3.1
#=GS F7Y364_MESOW/70-220 AC F7Y364.1
#=GS Y3761_ARATH/70-223 AC Q8RXW0.1
#=GS E4E7K4_PROAA/31-173 AC E4E7K4.1
#=GS F4BZG1_METCG/68-228 AC F4BZG1.1
#=GS B4F9Z2_MAIZE/2-142 AC B4F9Z2.1
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#=GS D5YAV2_MYCTU/70-209 AC D5YAV2.1
#=GS I0HUQ4_RUBGE/42-192 AC I0HUQ4.1
#=GS D2A9M6_SHIF2/129-273 AC D2A9M6.1
#=GS Q8F7J3_LEPIN/80-224 AC Q8F7J3.2
#=GS G8UMT9_TANFA/61-217 AC G8UMT9.1
#=GS H0Q7G4_ECOLI/129-273 AC H0Q7G4.1
#=GS F4A030_MAHA5/57-219 AC F4A030.1
#=GS H3ZCX1_9ALTE/123-267 AC H3ZCX1.1
#=GS E5X110_9BACE/42-220 AC E5X110.1
#=GS Q4UB35_THEAN/184-267 AC Q4UB35.1
#=GS E3VYU1_MIMIV/23-161 AC E3VYU1.1
#=GS D7HSN1_VIBCL/132-275 AC D7HSN1.1
#=GS C9AAS0_ENTCA/46-191 AC C9AAS0.1
#=GS A9DVE2_9RHOB/71-218 AC A9DVE2.1
#=GS E9UPF5_9ACTO/100-239 AC E9UPF5.1
#=GS E1DMS7_VIBPA/32-178 AC E1DMS7.1
#=GS H3GEB4_PHYRM/115-267 AC H3GEB4.1
#=GS E2RQQ1_CANFA/201-353 AC E2RQQ1.1
#=GS GLPG_ECOLI/129-273 AC P09391.5
#=GS GLPG_ECOLI/129-273 DR PDB; 3UBB A; 129-270;
#=GS GLPG_ECOLI/129-273 DR PDB; 3B45 A; 129-270;
#=GS GLPG_ECOLI/129-273 DR PDB; 3B44 A; 129-270;
#=GS GLPG_ECOLI/129-273 DR PDB; 2NRF A; 129-272;
#=GS GLPG_ECOLI/129-273 DR PDB; 3TXT A; 129-270;
#=GS GLPG_ECOLI/129-273 DR PDB; 2O7L A; 129-272;
#=GS GLPG_ECOLI/129-273 DR PDB; 2XTU A; 129-271;
#=GS GLPG_ECOLI/129-273 DR PDB; 2IRV A; 129-273;
#=GS GLPG_ECOLI/129-273 DR PDB; 2XOW A; 129-270;
#=GS GLPG_ECOLI/129-273 DR PDB; 2IRV B; 129-271;
#=GS GLPG_ECOLI/129-273 DR PDB; 2XTV A; 129-272;
#=GS GLPG_ECOLI/129-273 DR PDB; 2IC8 A; 129-272;
#=GS GLPG_ECOLI/129-273 DR PDB; 2NRF B; 129-272;
#=GS GLPG_ECOLI/129-273 DR PDB; 2XOV A; 129-271;
#=GS F3I8T1_PSESF/38-180 AC F3I8T1.1
#=GS E4EWJ6_PROAA/31-173 AC E4EWJ6.1
#=GS B9KTH9_RHOSK/36-184 AC B9KTH9.1
#=GS H5HLG6_ECOLX/55-205 AC H5HLG6.1
#=GS B0DIK5_LACBS/62-269 AC B0DIK5.1
#=GS B5SCZ5_RALSL/42-195 AC B5SCZ5.1
#=GS A6F3S1_9ALTE/150-307 AC A6F3S1.1
#=GS B6B7C0_9RHOB/55-215 AC B6B7C0.1
#=GS F8VKX2_SALBC/129-273 AC F8VKX2.1
#=GS Q3JMH1_BURP1/69-224 AC Q3JMH1.1
#=GS E4HVX4_PROAA/43-190 AC E4HVX4.1
#=GS D0B905_BRUME/67-234 AC D0B905.1
#=GS H3D5V4_TETNG/648-792 AC H3D5V4.1
#=GS F1WR83_MORCA/39-192 AC F1WR83.1
#=GS A9U4D9_PHYPA/101-245 AC A9U4D9.1
#=GS G9R5F5_9FIRM/42-189 AC G9R5F5.1
#=GS E7VRG4_SALMO/127-271 AC E7VRG4.1
#=GS B3HZN9_ECOLX/127-271 AC B3HZN9.1
#=GS Q3MC93_ANAVT/55-222 AC Q3MC93.1
#=GS H8IMS2_MYCIA/35-187 AC H8IMS2.1
#=GS A6FT71_9RHOB/71-218 AC A6FT71.1
#=GS B3TBN5_9ARCH/83-240 AC B3TBN5.1
#=GS F9SFW1_VIBSP/30-177 AC F9SFW1.1
#=GS F2ZLL8_9PSED/38-180 AC F2ZLL8.1
#=GS H3CC40_TETNG/212-268 AC H3CC40.1
#=GS E8VD25_BACST/216-358 AC E8VD25.1
#=GS G9MQA1_HYPVG/58-204 AC G9MQA1.1
#=GS A7GKE3_BACCN/43-186 AC A7GKE3.1
#=GS G6GZN2_9CHRO/65-229 AC G6GZN2.1
#=GS G9R5M3_9FIRM/49-197 AC G9R5M3.1
#=GS G2IAI3_9CLOT/186-329 AC G2IAI3.1
#=GS F4FYA9_METCR/39-177 AC F4FYA9.1
#=GS B5EBM2_GEOBB/97-239 AC B5EBM2.2
#=GS B4FMX3_MAIZE/126-270 AC B4FMX3.1
#=GS Q4UES4_THEAN/208-369 AC Q4UES4.1
#=GS F1R9M8_DANRE/157-310 AC F1R9M8.1
#=GS Q491A8_STRP1/51-194 AC Q491A8.1
#=GS H7MKB2_STRPN/52-195 AC H7MKB2.1
#=GS E4HAR3_PROAA/31-173 AC E4HAR3.1
#=GS C6ACT2_BARGA/71-240 AC C6ACT2.1
#=GS F3T558_STAAU/196-338 AC F3T558.1
#=GS F9DTR5_9BACL/51-194 AC F9DTR5.1
#=GS E4G6Q2_PROAA/43-190 AC E4G6Q2.1
#=GS H1N7P5_9PLAN/154-299 AC H1N7P5.1
#=GS F2KI72_PSEBN/136-285 AC F2KI72.1
#=GS Q7DAG7_MYCTU/105-244 AC Q7DAG7.1
#=GS D4DB47_TRIVH/364-513 AC D4DB47.1
#=GS C6EFF0_ECOBD/129-273 AC C6EFF0.1
#=GS H6KWD8_TREPG/47-199 AC H6KWD8.1
#=GS G6C6X4_9STRE/52-195 AC G6C6X4.1
#=GS E5V7B6_9BACE/42-220 AC E5V7B6.1
#=GS G1R1V7_NOMLE/169-326 AC G1R1V7.1
#=GS D4I3I5_ERWAC/127-270 AC D4I3I5.1
#=GS A4CL17_ROBBH/37-188 AC A4CL17.1
#=GS F7CUM8_CALJA/201-353 AC F7CUM8.1
#=GS G2LYB0_9XANT/34-189 AC G2LYB0.1
#=GS I1HEN4_BRADI/82-235 AC I1HEN4.1
#=GS F7DMC9_HORSE/191-348 AC F7DMC9.1
#=GS C9S8I5_VERA1/265-410 AC C9S8I5.1
#=GS E2MDA9_PSEUB/38-180 AC E2MDA9.1
#=GS B2S4L9_TREPS/47-199 AC B2S4L9.1
#=GS G7PU11_MACFA/210-367 AC G7PU11.1
#=GS C7YTV8_NECH7/327-472 AC C7YTV8.1
#=GS A9USK3_MONBE/2-157 AC A9USK3.1
#=GS E4BVD0_PROAA/43-190 AC E4BVD0.1
#=GS B6ADY7_CRYMR/93-250 AC B6ADY7.1
#=GS I0XK24_STAAU/196-338 AC I0XK24.1
#=GS B2RJ56_PORG3/45-201 AC B2RJ56.1
#=GS C6RP75_ACIRA/38-188 AC C6RP75.1
#=GS C5ZL88_BURPE/100-255 AC C5ZL88.1
#=GS A8TAH7_9VIBR/132-275 AC A8TAH7.1
#=GS I1LDT9_SOYBN/111-255 AC I1LDT9.1
#=GS I1HEN2_BRADI/68-212 AC I1HEN2.1
#=GS B4MYM0_DROWI/191-344 AC B4MYM0.1
#=GS Q87YK4_PSESM/132-280 AC Q87YK4.1
#=GS E3LSB6_CAERE/192-343 AC E3LSB6.1
#=GS D0NRZ6_PHYIT/230-340 AC D0NRZ6.1
#=GS E4I513_ENTFC/51-193 AC E4I513.1
#=GS C9B0V2_ENTCA/46-191 AC C9B0V2.1
#=GS H0GGM2_9SACH/174-332 AC H0GGM2.1
#=GS E4PG84_MARAH/132-277 AC E4PG84.1
#=GS D6T101_GARVA/58-202 AC D6T101.1
#=GS I0AN32_9BACT/56-219 AC I0AN32.1
#=GS D0L9N4_GORB4/54-196 AC D0L9N4.1
#=GS C9Q1V8_9VIBR/1-85 AC C9Q1V8.1
#=GS A7TD71_NEMVE/3-98 AC A7TD71.1
#=GS C9M497_LACHE/50-195 AC C9M497.1
#=GS A7BB19_9ACTO/45-189 AC A7BB19.1
#=GS E6M784_STALU/199-341 AC E6M784.1
#=GS A4CQ06_ROBBH/139-243 AC A4CQ06.1
#=GS H8KLE3_SOLCM/43-201 AC H8KLE3.1
#=GS D3ILF0_9BACT/98-240 AC D3ILF0.1
#=GS I0WW90_9NOCA/70-213 AC I0WW90.1
#=GS D6CWP0_9BACE/195-339 AC D6CWP0.1
#=GS Q2P0S6_XANOM/47-205 AC Q2P0S6.1
#=GS G7TLR7_9XANT/56-210 AC G7TLR7.1
#=GS I1NSJ4_ORYGL/45-194 AC I1NSJ4.1
#=GS H7VLK5_CAMCO/30-172 AC H7VLK5.1
#=GS D4GD36_PANAM/127-271 AC D4GD36.1
#=GS H3DZQ8_PRIPA/99-251 AC H3DZQ8.1
#=GS B2P0C7_ECO57/129-273 AC B2P0C7.1
#=GS B8CDU6_THAPS/271-458 AC B8CDU6.1
#=GS E0S2W4_BUTPB/46-187 AC E0S2W4.1
#=GS B9NRR0_9RHOB/55-202 AC B9NRR0.1
#=GS A0LGP8_SYNFM/103-245 AC A0LGP8.1
#=GS G6MU43_STRPN/52-195 AC G6MU43.1
#=GS F6ABE7_PSEF1/40-182 AC F6ABE7.1
#=GS G0SIX6_VIBMI/32-180 AC G0SIX6.1
#=GS E6R7U8_CRYGW/308-453 AC E6R7U8.1
#=GS F9GXR9_HAEHA/44-78 AC F9GXR9.1
#=GS B3M8G7_DROAN/154-310 AC B3M8G7.1
#=GS F4N4X8_YEREN/130-274 AC F4N4X8.1
#=GS E6XPA4_SHEP2/134-278 AC E6XPA4.1
#=GS F0KGT6_ACICP/39-192 AC F0KGT6.1
#=GS Q03YD8_LEUMM/53-197 AC Q03YD8.1
#=GS A7NI96_ROSCS/97-241 AC A7NI96.1
#=GS A1VZZ1_CAMJJ/30-170 AC A1VZZ1.1
#=GS A3KWB8_PSEAI/134-283 AC A3KWB8.1
#=GS C2LER4_PROMI/131-274 AC C2LER4.1
#=GS A1EQ19_VIBCL/71-218 AC A1EQ19.1
#=GS F6GV04_VITVI/125-269 AC F6GV04.1
#=GS F8D830_HALXS/132-257 AC F8D830.1
#=GS F4HTU9_ARATH/132-300 AC F4HTU9.1
#=GS A9G238_SORC5/102-253 AC A9G238.1
#=GS G3WKZ1_SARHA/1-147 AC G3WKZ1.1
#=GS H1C0Q0_ECOLX/129-273 AC H1C0Q0.1
#=GS Q6A9U0_PROAC/50-187 AC Q6A9U0.1
#=GS G8XA38_FLACA/35-187 AC G8XA38.1
#=GS B9WK77_CANDC/54-205 AC B9WK77.1
#=GS D7WXS7_9BACI/51-194 AC D7WXS7.1
#=GS E4XEZ2_OIKDI/126-276 AC E4XEZ2.1
#=GS G3YKB6_9RALS/40-198 AC G3YKB6.1
#=GS A2ERY3_TRIVA/274-415 AC A2ERY3.1
#=GS H2T3M6_TAKRU/167-320 AC H2T3M6.1
#=GS E0PGK7_STREI/51-193 AC E0PGK7.1
#=GS H1HBS1_9FLAO/46-189 AC H1HBS1.1
#=GS F4R5J0_MELLP/256-447 AC F4R5J0.1
#=GS H8GB38_9PSEU/135-274 AC H8GB38.1
#=GS H5P108_ECOLX/55-205 AC H5P108.1
#=GS G6B1C2_9BACT/42-223 AC G6B1C2.1
#=GS F2E2I8_HORVD/82-235 AC F2E2I8.1
#=GS Q2P0R5_XANOM/78-232 AC Q2P0R5.1
#=GS H4BHL7_STAAU/196-338 AC H4BHL7.1
#=GS B5CNI0_9FIRM/47-194 AC B5CNI0.1
#=GS E0PY04_STRPY/51-194 AC E0PY04.1
#=GS B8NQ23_ASPFN/241-386 AC B8NQ23.1
#=GS H5GI38_ECOLX/127-271 AC H5GI38.1
#=GS Y1171_MYCLE/83-234 AC P53426.1
#=GS G7PHH6_MACFA/44-187 AC G7PHH6.1
#=GS H4QNS7_ECOLX/129-273 AC H4QNS7.1
#=GS G0WIJ1_NAUDC/184-340 AC G0WIJ1.1
#=GS G6X8P4_MYCAB/63-211 AC G6X8P4.1
#=GS Q16V56_AEDAE/185-336 AC Q16V56.1
#=GS G0DK39_9GAMM/39-190 AC G0DK39.1
#=GS F8EFM4_RUNSL/37-194 AC F8EFM4.1
#=GS F8L598_SIMNZ/42-189 AC F8L598.1
#=GS C0Q0J8_SALPC/126-270 AC C0Q0J8.1
#=GS Q4Z6I9_PLABA/15-162 AC Q4Z6I9.1
#=GS D6HHB1_STAAU/196-338 AC D6HHB1.1
#=GS Q2P391_XANOM/34-189 AC Q2P391.1
#=GS I1BV42_RHIO9/39-154 AC I1BV42.1
#=GS Q9C6A2_ARATH/147-302 AC Q9C6A2.1
#=GS D3ENM9_UCYNA/47-192 AC D3ENM9.1
#=GS D2GGQ4_STAAU/196-338 AC D2GGQ4.1
#=GS F9NTV8_PROAA/72-214 AC F9NTV8.1
#=GS B3WS88_ECOLX/55-205 AC B3WS88.1
#=GS E7QRK4_9EURY/118-275 AC E7QRK4.1
#=GS B4PD83_DROYA/131-287 AC B4PD83.1
#=GS F8KVW2_PARAV/234-391 AC F8KVW2.1
#=GS E8GDR0_SALMO/127-271 AC E8GDR0.1
#=GS B3LIC5_YEAS1/174-332 AC B3LIC5.1
#=GS H8M1T9_SALTM/129-273 AC H8M1T9.1
#=GS G3ANJ5_SPAPN/202-352 AC G3ANJ5.1
#=GS D1R5U6_9CHLA/234-391 AC D1R5U6.1
#=GS A4BB55_9GAMM/30-176 AC A4BB55.1
#=GS E6L8V9_CAMUP/37-178 AC E6L8V9.1
#=GS A8MDB3_CALMQ/50-191 AC A8MDB3.1
#=GS A7RJJ9_NEMVE/287-431 AC A7RJJ9.1
#=GS H6RFS1_9BACT/38-189 AC H6RFS1.1
#=GS G0KVQ4_DANRE/197-354 AC G0KVQ4.1
#=GS Q0FQV8_9RHOB/55-215 AC Q0FQV8.1
#=GS H3UI84_STAEP/196-339 AC H3UI84.1
#=GS C3QSL0_9BACE/59-204 AC C3QSL0.1
#=GS B7AKY8_9BACE/42-220 AC B7AKY8.1
#=GS F7DQ26_MONDO/659-803 AC F7DQ26.1
#=GS E4BZ76_PROAA/31-173 AC E4BZ76.1
#=GS H3NVJ5_9GAMM/58-207 AC H3NVJ5.1
#=GS F3EVE9_9PSED/38-179 AC F3EVE9.1
#=GS F9BV16_VIBCL/132-275 AC F9BV16.1
#=GS O07502_BACFI/109-161 AC O07502.1
#=GS F0YGF4_AURAN/17-77 AC F0YGF4.1
#=GS F0CCI4_9XANT/55-199 AC F0CCI4.1
#=GS C5BUR2_BEUC1/143-286 AC C5BUR2.1
#=GS B4EZN0_PROMH/131-274 AC B4EZN0.1
#=GS H3AAW3_LATCH/158-310 AC H3AAW3.1
#=GS Q0HII4_SHESM/45-196 AC Q0HII4.1
#=GS F2EAI4_HORVD/74-225 AC F2EAI4.1
#=GS E3CBX3_STRPA/52-194 AC E3CBX3.1
#=GS E6D625_PROAA/31-173 AC E6D625.1
#=GS F6UQN5_HORSE/44-187 AC F6UQN5.1
#=GS Q00YL9_OSTTA/110-150 AC Q00YL9.1
#=GS I1M4X3_SOYBN/76-220 AC I1M4X3.1
#=GS B1V7S6_CLOPF/197-338 AC B1V7S6.1
#=GS Q4FR55_PSYA2/53-205 AC Q4FR55.1
#=GS A8Q010_MALGO/197-320 AC A8Q010.1
#=GS Q53KX4_ORYSJ/58-216 AC Q53KX4.1
#=GS I0PTH8_MYCAB/68-206 AC I0PTH8.1
#=GS F2CGS1_STRSA/52-194 AC F2CGS1.1
#=GS B4HWM4_DROSE/1086-1232 AC B4HWM4.1
#=GS A8UKJ0_9FLAO/64-218 AC A8UKJ0.1
#=GS F5H8L2_HUMAN/99-250 AC F5H8L2.1
#=GS A3V592_9RHOB/72-217 AC A3V592.1
#=GS F6GC23_LACS5/46-189 AC F6GC23.1
#=GS A3V5L6_9RHOB/56-216 AC A3V5L6.1
#=GS C4R609_PICPG/261-417 AC C4R609.1
#=GS C0PEN2_MAIZE/19-152 AC C0PEN2.1
#=GS F0YMN8_AURAN/1-141 AC F0YMN8.1
#=GS A6CC82_9PLAN/63-212 AC A6CC82.1
#=GS F7DJZ3_ORNAN/1-145 AC F7DJZ3.1
#=GS F3SNT4_STAWA/196-338 AC F3SNT4.1
#=GS D4YSE3_9LACO/50-194 AC D4YSE3.1
#=GS F5SSB5_9GAMM/53-210 AC F5SSB5.1
#=GS G3STC7_LOXAF/649-792 AC G3STC7.1
#=GS C1CH22_STRZJ/52-195 AC C1CH22.1
#=GS F5WIR5_STAAU/1-55 AC F5WIR5.1
#=GS Q72N96_LEPIC/35-186 AC Q72N96.1
#=GS C6XN07_HIRBI/77-229 AC C6XN07.1
#=GS F9VIG1_ARTSS/186-329 AC F9VIG1.1
#=GS D5U0R9_THEAM/58-218 AC D5U0R9.1
#=GS B8K9L0_VIBPA/26-171 AC B8K9L0.1
#=GS B0C845_ACAM1/62-225 AC B0C845.1
#=GS E7IPT6_ECOLX/129-273 AC E7IPT6.1
#=GS A6AVU8_VIBHA/132-275 AC A6AVU8.1
#=GS E1XAR8_HAEI1/44-188 AC E1XAR8.1
#=GS Q8PIZ7_XANAC/78-232 AC Q8PIZ7.1
#=GS H0RAC4_9ACTO/78-217 AC H0RAC4.1
#=GS F2L8H3_BURGS/33-187 AC F2L8H3.1
#=GS D8QTV1_SELML/46-197 AC D8QTV1.1
#=GS H6C1X5_EXODN/70-218 AC H6C1X5.1
#=GS C6WCG7_ACTMD/128-266 AC C6WCG7.1
#=GS F9C2Z9_VIBCL/132-275 AC F9C2Z9.1
#=GS RHBL1_MOUSE/174-331 AC Q8VC82.1
#=GS F9V1Y2_MYCBO/71-223 AC F9V1Y2.1
#=GS Q1VW99_9FLAO/50-192 AC Q1VW99.1
#=GS Q7UL82_RHOBA/62-218 AC Q7UL82.1
#=GS D8JDW0_ACISD/39-192 AC D8JDW0.1
#=GS G2QRK1_THITE/269-414 AC G2QRK1.1
#=GS D3LLP0_MICLU/65-207 AC D3LLP0.1
#=GS H0AVG6_STAAU/196-338 AC H0AVG6.1
#=GS B9KG76_CAMLR/37-176 AC B9KG76.1
#=GS Q4MYT8_THEPA/304-422 AC Q4MYT8.1
#=GS G3W6E5_SARHA/42-186 AC G3W6E5.1
#=GS Q3J4G6_RHOS4/54-214 AC Q3J4G6.1
#=GS D3QCK4_STALH/195-337 AC D3QCK4.1
#=GS I0VHU8_SHIFL/110-254 AC I0VHU8.1
#=GS C3NGL5_SULIN/64-204 AC C3NGL5.1
#=GS H0X714_OTOGA/44-187 AC H0X714.1
#=GS G9RFK2_9ENTR/127-271 AC G9RFK2.1
#=GS H8KST2_SOLCM/59-205 AC H8KST2.1
#=GS RHDF1_CALMO/647-791 AC B1MT31.1
#=GS H0IMD6_MYCAB/29-177 AC H0IMD6.1
#=GS I0U4L9_BACTR/52-196 AC I0U4L9.1
#=GS D0DJ41_9LACO/52-197 AC D0DJ41.1
#=GS E4TL12_MARTH/163-260 AC E4TL12.1
#=GS H1L7N9_GEOME/70-234 AC H1L7N9.1
#=GS Q3AIE2_SYNSC/35-177 AC Q3AIE2.1
#=GS A3J4Y8_9FLAO/56-207 AC A3J4Y8.1
#=GS E8UWS6_THEBF/62-227 AC E8UWS6.1
#=GS B7FPD5_PHATC/383-538 AC B7FPD5.1
#=GS RHBL2_TOXGO/104-249 AC Q695T9.1
#=GS G3RDB0_GORGO/239-396 AC G3RDB0.1
#=GS F8ZX39_VIBCL/32-179 AC F8ZX39.1
#=GS D7KV51_ARALL/116-260 AC D7KV51.1
#=GS A8GYP6_SHEPA/134-278 AC A8GYP6.1
#=GS C3LPU1_VIBCM/132-275 AC C3LPU1.1
#=GS Q0I922_SYNS3/32-174 AC Q0I922.1
#=GS A0LQS9_ACIC1/117-256 AC A0LQS9.1
#=GS F1TUN5_PROAA/43-190 AC F1TUN5.1
#=GS E6LGY2_9ENTE/49-195 AC E6LGY2.1
#=GS H1VBL0_COLHI/328-473 AC H1VBL0.1
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