GenomeNet

Database: Pfam
Entry: SMRP1
LinkDB: SMRP1
Original site: SMRP1 
#=GF ID   SMRP1
#=GF AC   PF15181.1
#=GF DE   Spermatid-specific manchette-related protein 1
#=GF AU   Eberhardt RY, Coggill P, Hetherington K
#=GF SE   Jackhmmer:Q8NCR6
#=GF GA   27.00 27.00;
#=GF TC   85.50 85.50;
#=GF NC   25.50 25.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   15242845
#=GF RT   Characterization of ciliated bronchial epithelium 1, a ciliated
#=GF RT   cell-associated gene induced during mucociliary differentiation.
#=GF RA   Yoshisue H, Puddicombe SM, Wilson SJ, Haitchi HM, Powell RM,
#=GF RA   Wilson DI, Pandit A, Berger AE, Davies DE, Holgate ST, Holloway
#=GF RA   JW;
#=GF RL   Am J Respir Cell Mol Biol. 2004;31:491-500.
#=GF CC   This family of proteins, SMRP1, is thought to have a role in
#=GF CC   spermatogenesis and may be involved in differentiation or
#=GF CC   function of ciliated cells [1]. This family of proteins is found
#=GF CC   in eukaryotes. Proteins in this family are typically
#=GF CC   approximately 260 amino acids in length.
#=GF SQ   38
#=GS F7FHH7_ORNAN/1-233  AC F7FHH7.1
#=GS H2QX61_PANTR/1-262  AC H2QX61.1
#=GS F7HCD4_MACMU/1-262  AC F7HCD4.1
#=GS F7HCD7_MACMU/1-59   AC F7HCD7.1
#=GS H2PRW5_PONAB/1-83   AC H2PRW5.1
#=GS G1M7Y3_AILME/1-278  AC G1M7Y3.1
#=GS F7DSY3_CALJA/1-263  AC F7DSY3.1
#=GS F6YKD2_MONDO/1-142  AC F6YKD2.1
#=GS G9L5D0_MUSPF/1-216  AC G9L5D0.1
#=GS G5B056_HETGA/1-266  AC G5B056.1
#=GS H0VNI3_CAVPO/1-248  AC H0VNI3.1
#=GS F6ZLJ8_HORSE/1-264  AC F6ZLJ8.1
#=GS H9GAR2_ANOCA/1-269  AC H9GAR2.1
#=GS F7CUE2_MOUSE/1-188  AC F7CUE2.1
#=GS G1P805_MYOLU/1-272  AC G1P805.1
#=GS Q5T597_HUMAN/1-121  AC Q5T597.1
#=GS A2ANN9_MOUSE/1-202  AC A2ANN9.1
#=GS G1QYF5_NOMLE/1-262  AC G1QYF5.1
#=GS G3X195_SARHA/1-131  AC G3X195.1
#=GS H0XS03_OTOGA/1-260  AC H0XS03.1
#=GS SMRP1_HUMAN/1-262   AC Q8NCR6.2
#=GS E2RC75_CANFA/1-278  AC E2RC75.1
#=GS SMRP1_MACFA/1-262   AC Q95LU0.2
#=GS G3U5X0_LOXAF/1-262  AC G3U5X0.1
#=GS F6Z9H3_MONDO/1-221  AC F6Z9H3.1
#=GS D3ZGG6_RAT/1-230    AC D3ZGG6.1
#=GS G3X193_SARHA/1-221  AC G3X193.1
#=GS G3I849_CRIGR/1-119  AC G3I849.1
#=GS F1SEB3_PIG/1-272    AC F1SEB3.1
#=GS E1C3B8_CHICK/1-257  AC E1C3B8.1
#=GS SMRP1_BOVIN/1-276   AC Q32KP0.1
#=GS SMRP1_MOUSE/1-260   AC Q2MH31.1
#=GS D4A9U1_RAT/1-261    AC D4A9U1.1
#=GS G3X194_SARHA/1-250  AC G3X194.1
#=GS G3QQH0_GORGO/1-272  AC G3QQH0.1
#=GS D2I3F2_AILME/1-233  AC D2I3F2.1
#=GS G1SMH3_RABIT/1-262  AC G1SMH3.1
#=GS H0Y454_HUMAN/1-122  AC H0Y454.1
F7FHH7_ORNAN/1-233             ..MFLFAHKTKTPTSTYTDSYRVPSSIKQ.SYEEPPLKAWEENKFVTqpvaQGLTQIAtKKP.VEQRLL.EGMTQRAPNQFASQPPIPSSAYLPHKYWISEAEapwarA......ER.......FNPVLENG.......DRYAMWRTGPDNSAgWNRYSSHLPPLPKEAGR.ETVFRPTAPDYPPKSERQNDYa....pgEREAVVNMIDTLSRSQL-PSIQV----PQHVPGRLPFQGYGSRCTGRHYCLR..GMDYFVDGPPPSRR.P--------------...-----------.........-------------l.............................................
H2QX61_PANTR/1-262             ..MFLFSRKTRTPISTYSDSYRAPTSIKE.VYKDPPLCAWEANKFLT....PGLTHTM.ERH.VDPEAL.QKMAKCAVQDYTYRGSISGHPYLPEKYWLSQEE.....A......DK.......CSPNYLGS.......DRYNTWRMEPYNSScCNKYTTYLPRLPKEARM.ETEVRGMPLECPPRPERLNAY.......EREVMVNMLNSLSRNQQLPRITPRCGCVDPLPGRLPFHGYESACSGRHYCLR..GMDYYASGSPCTDR.RLRPWCREQPTMCTS...LRAPARNAVCC.........YNSPAVILPISEP..............................................
F7HCD4_MACMU/1-262             ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLCAWEANKFLT....PGLTHTM.EQH.VDPEAL.QKMAKCAVQDYTYRGPISGHPYLPEKYWLSQEE.....A......DK.......CSPNYLGS.......NRYNTWRMEPYNSScCNKYTTYLPRLPKEAGM.ETAVRGMPLECPPKPERLNAY.......EREVMVNMLNSLSRNQQLPRITPRCGCVDPLPGRLPFHGYESACSGRHYCLR..GMDYYASGAPCTDR.RLRPWCRELPTLCTS...LRAPARNAVCC.........YNSPAVILPISEP..............................................
F7HCD7_MACMU/1-59              ..---------------------------.-----------------....-------.---.------.---------------------------------.....-......--.......--------.......--------------.----------------M.ETAVRGMPLECPPKPERLNAY.......EREVMVNMLNSLSRNQQLPRITPRCGCCP-----------------------..--------------.---------------...-----------.........-------------acvppyeh......................................
H2PRW5_PONAB/1-83              ..---------------------------.-----------------....-------.---.------.---------------------------------.....-......--.......--------.......--------------.----------------M.ETAVRGMPLECPPKPERLNAY.......EREVMVNMLNSLSRNQQLPRITPRCGCVPPYEHRP-----------------..--------------.---------------...-----------.........-------------gmqcavttpppsyypypnlrwdtshf....................
G1M7Y3_AILME/1-278             ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.QRH.VDPEAL.QKMVKCAVQDYSYKGSIPGHPYFPEKYWLCQEE.....AslcpttQK.......WNPYYLCD.......DRYNIWRMGPYNCTgWNKYTTCLPRLPKEAGM.ETAVRGMPLQCPPKPERLNAY.......EREVVVNMLNSLSRNQPLPQITPGCGCVDTLPGRLSFQGYESPCSGRHYCLR..GMDYYTTGAPCKER.RFRPLCTEQRTARSV...SPYEHRSGMQCtvithppsyYPCPNLS------kwdtshf.......................................
F7DSY3_CALJA/1-263             ..MYLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFLT....PGLTHTM.ERH.VDPEAL.QKMAKCALQDYTYRGSISGHPYLPEKYWLSQEE.....A......DK.......CTTNYLSS.......DRYNTWRTEPYNSScCNKYTTYLPRLPKEAGM.ETAVRGMPLECPPKPERLNAY......aEREVVVNMLNSLSQNQQLPRIVPRCGCVDPLPGRLPFHGYESACSGRHYCLR..GMDYYASGTPCTDR.RLRPWCREQPTMCTS...LRAPARNAVCC.........YNSPAVILPISEP..............................................
F6YKD2_MONDO/1-142             ..---------------------------.-----------------....-------.---.------.---------------------------------.....-......--.......--------.......-------TGPYNSSgWNKYTTYLPRLPKEAGM.ETMMRGMPLDYPPKPDRFNNY.......EREVVVNMLNSLSRNQL-PSIQP----RYTVPGRLPFQGYDSPCTGRHYCLR..GMDYYATGAPSNER.HL-----TQPTECPP...LQPQTRNELCC........lIPPPAITLSL---ykp...........................................
G9L5D0_MUSPF/1-216             ..---------------------------.-----------------....-GLTQTM.QRH.VDPEAL.QKMVKCAVQNYSYKGSISGHPYFPEKYWLCQEE.....-......DK.......WTPYYLCG.......DRYNTWRMGPYNCTgWNKYTTCLPRLPKEAGM.ETAVRGMPLPCPPKPERLNAY.......EREVVVNMLNSLSRNQPLPQITRRCGCVDPLPGRLPFQGYESPCSGRHYCLR..GMDYYVTGAPCAER.RFRPLCTEEPTECIA...LRAPARNAMCC.........YNSPAVILPLSQP..............................................
G5B056_HETGA/1-266             ..MFLFSNKTKTPISTYTDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.KRH.TDPEAL.QKMAKCATQDYSCKSSMSGHPYLPEKYWLSQEE.....E......NK.......CCPSYLGS.......DPYCTWRTRPYSSSyWNKYTTCLPRLPKEAGM.ETAVRGMPLECPPKPERLNAY.......ERDVVVNMLNSLSRNRTLPQITSRCGCVEPLPGRLPFQGYKSACSGRHYCLR..GMDYCTPGPPCTERrHLRALCPEQPTVRVSqcsSGAPARNALCC.........YNCPAVILPISEP..............................................
H0VNI3_CAVPO/1-248             ..MYLFSRKTKTPISTYTDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.KRH.TDPEAL.QKMARCATQDYNYKSSVSGHPYLPEKYWLSQEE.....E......NK.......CCPSYLES.......DPYCTWRTGPYNSTsWNKYSTCLPRLPKDAGM.DTAVRGMTLECPPKPERLNAY......aERDVVANMLNSLPRNRTLPQITPRCGCVDPLPGRLPFRGYESPCSLRR----..--------APPT--.-CGALCPDQPTECIT...LRPPARNALCC.........YNSPAVILPISEP..............................................
F6ZLJ8_HORSE/1-264             ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTT.QRH.VDPEAL.RKMVKCAVQDYTYKGSVPGHPYLPEKYWLSQEE.....A......DK.......CTPNYLCS.......NRYNTRRMGPYNYTgWNKYATCLPRLPKEAGM.ETAVRGMPLEYPPKPERLNAY.......ARPPRLRAANPANKSHPLPL-QP-----RPLPGRLAPETQVLACSSSSVCVR..-LESCEGGPEPSPL.RVLPCLPTASSCRTV...SPYDHRPGMQCavitpplsyYPCPNLRWDTSH-f.............................................
H9GAR2_ANOCA/1-269             ..MFLFARKTRTPISTYTDSYRPPNTLKK.TFEDPPLALWSENKFLT....QGLTVPR.VDHpIDQNHL.DKLVKRAVQEYAYMNPTEASVYRPYKYWVTREE.....A......DKdlfshqkFNPVFTGD.......DRYATWRTGPYNSAgWNRYTTYLPRIPKESGM.ESILR------PPKPERLNNY.......EREVVVNMLNSLSRKQL-PSLQH----HYTVPGRMPYQGYYSPCTGRHYCLR..GMDYYVDGAPNNER.QISQLEYSLQNIYKV...NICDHHQEMTLc......arM------------papqpsfpymnlrwdtshf...........................
F7CUE2_MOUSE/1-188             .x---------------------------.-----------------....-------.---.------.----------------------LPEKYWLSPDE.....E......DK.......CCPSYLDN.......DRYNTWKTSPCSNY.WNKYTGCLPRLSKDTGM.ES-VRGMPLEYPPKQERLNAY.......EREVVVNMLNSLSRNRTLPQIVPRCGCVDPLPGRLPYQGYESPCSGRHYCLR..GMDYCTTREPSTER.RLRPLCSQQPTVRSV...SPFGHRPGMQCavttpppsfYPYPNLRWDTSH-f.............................................
G1P805_MYOLU/1-272             ..MFLFSRKTRTPISTYTDSYRAPNSIKK.VYNDPPLWAWEPNKFVS....RGPPKTF.QRP.VDQEAL.EKMVKCAVRDYTYKSSIPGHPYLPEKYWLSQKE.....A......DK.......CNPNYLCS.......DWGNAWRMGPYCCTdWNKCTTCLPRLPKEAGM.ETAVRGMPLQYPPKPERLNAY......aEREVVVNMLNSLSRYQTLPQITPRCGCVDPLPGRLPFQGYESPCSGRHYCLR..GIDYCVAGAPCTER.RLQPLCPSQPTVRSV...SPSEHRPGMHCavitplrpyYPYPNLRWDTSH-f.............................................
Q5T597_HUMAN/1-121             ..---------------------------.--------AWEANKFLT....PGLTHTM.ERH.VDPEAL.QKMAKCAVQDYTYRGSISGHPYLPEKYWLSQEE.....A......DK.......CSPNYLGS.......DWYNTWRMEPYNSScCNKYTTYLPRLPKVSVApSTDVWGLGHAYPT--------.......----------------------------------------------------..--------------.---------------...-----------.........-------------tsqttv........................................
A2ANN9_MOUSE/1-202             ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.HRH.VDPEAL.QKMTKCAAQDYTYKSSISGHPYLPEKYWLSPDE.....E......DK.......CCPSYLDN.......DRYNTWKTSPCSNY.WNKYTGCLPRLSKDTGM.ES-VRGMPLEYPPKQERLNAY.......G---------------------------------------------------..--------------.---------------...-----------.........-------------vcrpsvtgqecnvllqlprhhftriptldgtqvtsrrlvvprettm
G1QYF5_NOMLE/1-262             ..MFLFSRKTRTPISTYSDSYRAPTSIKE.VYKDPPLCAWEANKFLT....PGLTHTM.ERH.VDPEAL.QKMAKCAVQDYTYRGSISGHPYLPEKYWLSQEE.....A......DK.......CSPNYLGS.......DRYNTWRMEPYNSScCNKYTTYLPRLPKEAGM.ETAVRGMPLECPPKPERLNAY.......EREVMVNMLNSLSRNQQLPRITPRCGCVDSLPGRLPFHGYESACSGRHYCLR..GMDYYASGAPCTDR.RLRPCARSNRLMCTS...LRAPARNAVCC.........YNSPAVILPISEP..............................................
G3X195_SARHA/1-131             ..---------------------------.-----------------....-------.---.------.---------------------------------.....-......--.......--------.......--------------.----------------M.EPATPGTPVDGPPKSERFNNY.......EREVMVNMLNSLTRKQL-PSIQP----RYTVPGRLPFQGYDSPCTGRHYCLR..GMELYVTEAPIKEC.HLTQLTKNQKSIRSI...PPLNHRPGMKCmisnlpprlYDFENVKWN----tshf..........................................
H0XS03_OTOGA/1-260             ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKYVT....RGLTQTM.ERH.VDPEAL.QKMVKCATQDYTYKGSIPGHPYFPEKYWLSQEE.....A......DK.......CSSNYLGN.......DQY-TWKTGPYNTC.FNKYTTCLPRLPKEAGM.ETAVRGMPLECPPKPERLNAY.......EREVVANVLNSLSRNQPLPQITPRCGCMDPLPGRLPFHGYESSCSGRHYCLR..GMDYCVSGAPCTDR.RLRPLCREQPTGCIA...LRAPTRNTMCC.........YNSPAIILPISEP..............................................
SMRP1_HUMAN/1-262              ..MFLFSRKTRTPISTYSDSYRAPTSIKE.VYKDPPLCAWEANKFLT....PGLTHTM.ERH.VDPEAL.QKMAKCAVQDYTYRGSISGHPYLPEKYWLSQEE.....A......DK.......CSPNYLGS.......DWYNTWRMEPYNSScCNKYTTYLPRLPKEARM.ETAVRGMPLECPPRPERLNAY.......EREVMVNMLNSLSRNQQLPRITPRCGCVDPLPGRLPFHGYESACSGRHYCLR..GMDYYASGAPCTDR.RLRPWCREQPTMCTS...LRAPARNAVCC.........YNSPAVILPISEP..............................................
E2RC75_CANFA/1-278             ..MFLFSHKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....RGLTQTM.QRH.VDPEAL.QKMVKCAVQDYSYKGFIPGHPYFPEKYWLCQEE.....V......DK.......CNPYHLCG.......DRYNLWRMGPYNCTgWNKYTTCLPRLPKEAGM.ETACRGMPLRCPPKPERLNAYglgaagaEREVVVNMLNSLSRNQPLPQITSRCGCGDPLPGRLPFQGYESACSGRHYCLR..GMDYCATRAPCTER.RLRSLCTQQPTVSSV...SPCEHRPGMQCavitpppsyYPCPNLRWDTSH-f.............................................
SMRP1_MACFA/1-262              ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLCAWEANKFLT....PGLTHTM.EQH.VDPEAL.QKMAKCAVQDYTYRGPISGHPYLPEKYWLSQEE.....A......DK.......CSPNYLGS.......NRYNTWRMEPYNSScCNKYTTYLPRLPKEAGM.ETAVRGMPLECPPKPERLNAY.......EREVMVNMLNSLSRNQQLPRITPRCGCVDPLPGRLPFHGYESACSGRHYCLR..GMDYYASGAPCTDR.RLRPWCRELPTLCTS...LRAPARNAVCC.........YNSPAVILPISEP..............................................
G3U5X0_LOXAF/1-262             ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.ERH.VDPEAL.QKMVRCAVQNYSYKNCIPGHPYFPEKYWLSQEE.....A......DK.......CNPNYLYG.......DRYATWRIGPYNSTgWNKYTTCLPRLPKEAGM.ETVVRGMPLECPPKPERLNAY.......EREVVVNMLNSLSRNQPLPQITPRCGCVDPLPGRLPFQGYESRCSGRHYCLR..GMDYYATGAPCLQR.RLRPGCCAQPTGCIS...LPTPTRNTMCC.........YNSPAVVLPLSEP..............................................
F6Z9H3_MONDO/1-221             ..MFLFAHKTKTPISTYTDSYRAPASIKQ.DYKDPPLWAWEENKFVS....PGLKKPMlEQH.VDQQSL.EKMVKRAVEEYSYKGSVPGNPYLPQKYWISEAE.....A......ER.......YNPAFISG.......DRYGAWRTGPYNSSgWNKYTTYLPRLPKEAGM.ETMMRGMPLDYPPKPDRFNNY.......EREVVVNMLNSLSRNQL-PSIQP----RYTVPGRLPFQGYDSPCTGRHYCLR..GMDYYATGAPSNER.HL-------------...-----------.........-------------..............................................
D3ZGG6_RAT/1-230               ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.HRH.VDPEAL.QKMAKCAAQDYTYKSSISGHPYLPEKYWLSPDE.....E......DK.......CCTSYLDN.......DRYNTWKTSPCSNY.WNKYTTCLPRLYKDTGM.ESEVRGMPLEYPPKPERLNAY.......----------GVSRYATTGQ---ECSVLL----QLP----------RHHTTHfpTLD----GTQVTSR.R--PVVPRETTMLSI...LNLCLRLFLST.........LPSKTLTRPREE-v.............................................
G3X193_SARHA/1-221             mv---------------------------.-----------------....-------.ESH.VDQQSL.EKVVKNAVEDYIHKPPVTGKPYIPQKYWIPEAE.....EgdqcepKK.......YKPTFISG.......DRYATGKTGPYNNTgWNKYPTCLPRLPKENGM.EPATPGTPVDGPPKSERFNNY.......EREVMVNMLNSLTRKQL-PSIQP----RYTVPGRLPFQGYDSPCTGRHYCLR..GMELYVTEAPIKEC.HLTQL--TVRSIRSI...PPLNHRPGMKCmisnlpprlYDFENVKW-----ntshf.........................................
G3I849_CRIGR/1-119             ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.HRH.VDPEAL.QKMVKCAAQDYTYKNSIAGHPYLPEKYWLSQDE.....A......EV.......--------.......--------------.-----------------.---------------------.......----------------------------------------------------..--------------.---------------...-----------.........-------------rvgyqsqniscffrlvdrdsvwg.......................
F1SEB3_PIG/1-272               ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTHTA.QRH.VDPEAL.QKMVKCAVQDYSYKGSIPGHPYLPEKYWLCQEE.....A......DK.......CNPNYLCG.......NRYNTWRMGPYSCTgWNRCNVYLPQLPKEAGM.ETVVRGMPLVYPPKPERLNAY......aEREVVVNMLNSLSRNQPLPQITPRCGCADPLPGRLPFQGYESACSGRHYCLR..GMDYYVAGPPCTER.RLRPLCAEQPTVRSV...SPCEHRPGMHCavltppqsyYPCPNLRWDTSH-f.............................................
E1C3B8_CHICK/1-257             ..MFLFAQKHKTPVSTYTDSYRPPCTMKKaIYEKAPLQLWRDNKFVT....QGLTMPQ.EQN.MSHQGQpEKLIKAVMQEYLYRNAIDPTAYWPEKYWLTKPE.....-......EK.......YSPVFVNE.......DKYITWRTGPYSSAaWNKYSTYLPLPPKEKRM.ETFLQSIPVPYPPKPACLNQY.......EREVVGDMLRRLSRLSP-PSLQP----VYTMSGRTPFQGYYSPCSGRHYCLR..GMDYYVDGDPTIRR.HLNAL--AERTEYPV...LQLQPYSDVLC........kYTSPPAIIPMYEP..............................................
SMRP1_BOVIN/1-276              ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTHTA.QRH.VDPDAL.QKMLKCAVQDYSYKGSIPSHPYFPEKYWLCPEE.....A......DR.......CNPNYLCGnpnylcsNQYNTWRMGPYNC-.WNKCTTYLPRLPKEAGM.ETVVRGMPLVYPPKPERLNAY.......EREVVVNMLNSLSRNQPLPQITPRCGCVDPLPGRLPFQGYESACSGRHYCLR..GMDYCVSGPPCTER.RLRPLCTELPTVRSV...SPCEHRSGMQCavitpqpsyYPCPNLRWDTSH-f.............................................
SMRP1_MOUSE/1-260              ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.HRH.VDPEAL.QKMTKCAAQDYTYKSSISGHPYLPEKYWLSPDE.....E......DK.......CCPSYLDN.......DRYNTWKTSPCSNY.WNKYTGCLPRLSKDTGM.ES-VRGMPLEYPPKQERLNAY.......EREVVVNMLNSLSRNRTLPQIVPRCGCVDPLPGRLPYQGYESPCSGRHYCLR..GMDYCTTREPSTER.RLRPLCSQQPTECVA...LRSPARNAMCC.........YNSPAIILPVSQP..............................................
D4A9U1_RAT/1-261               ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.HRH.VDPEAL.QKMAKCAAQDYTYKSSISGHPYLPEKYWLSPDE.....E......DK.......CCTSYLDN.......DRYNTWKTSPCSNY.WNKYTTCLPRLYKDTGM.ESEVRGMPLEYPPKPERLNAY.......EREVVVNMLNSLSRNRTLPQIVPRCGCVDPLPGRLPYRGYESPCSGRHYCLR..GMDYCTTGEPSTER.RLRPLCSQQPTEYVA...LRPPARNAVCC.........YNSPAIILPISQP..............................................
G3X194_SARHA/1-250             ..MFLFAHKTKTPLSTYADSYRHPATIKQ.DYKDPPLWAWEENKFIT....KGLRKPMvESH.VDQQSL.EKVVKNAVEDYIHKPPVTGKPYIPQKYWIPEAE.....-......EK.......YKPTFISG.......DRYATGKTGPYNNTgWNKYPTCLPRLPKENGM.EPATPGTPVDGPPKSERFNNY.......EREVMVNMLNSLTRKQL-PSIQP----RYTVPGRLPFQGYDSPCTGRHYCLR..GMELYVTEAPIKEC.HLTQL--TEYQEYTT...PQPQARNEMHD.........-------------lkppsptv......................................
G3QQH0_GORGO/1-272             ..MFLFSRKTRTPISTYSDSYRAPTSIKE.VYKDPPLCAWEANKFLT....PGLTHTM.ERH.VDPEAL.QKMAKCAVQDYTYRGSISGHPYLPEKYWLSQEE.....A......DK.......CSPNYLGS.......DRYNTWRMEPYNSScCNKYTTYLPRLPKEARI.ETAVRGMPLECPPRPERLNAY......aEREVMVNMLNSLSRNQQLPRITPRCGCVDPLPGRLPFHGYESACSGRHYCLR..GMDYYASGAPCTDR.RLRPWCREQPTVRCV...PPYEHRPGMQCavttpppsyYPYPNLRWDTSH-f.............................................
D2I3F2_AILME/1-233             ..MFLFSRKTKTPISTYSDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.QRH.VDPEAL.QKMVKCAVQDYSYKGSIPGHPYFPEKYWLCQEE.....-......EK.......WNPYYLCD.......DRYNIWRMGPYNCTgWNKYTTCLPRLPKEAGM.ETAVRGMPLQCPPKPERLNAY.......EREVVVNMLNSLSRNQPLPQITPGCGCVDTLPGRLSFQGYESPCSGRHYCLR..GMDYYTTGAPCKER.RFRPLCTEQRT----...-----------.........-------------..............................................
G1SMH3_RABIT/1-262             ..MFLFSRKTKTPISTYNDSYRAPTSIKE.VYKDPPLWAWEANKFVT....PGLTQTM.ERH.VDPEAL.RKMVKCNNQDYTYKSSISGHPYLPEKYWLSQYE.....A......DK.......CSPCYLSS.......DRYNTWRTAPYNSPyWNKYTTCLPRLPKDAGM.ETVARGMPLEYPPKPERLNAY.......EREVVVNMLNSLSRNQQLPRVMPRCGCLDPLPGRLPYLGYESACSGRHYCLR..GMDYCTGEAPYTER.RLRPLCAEQPTGCVT...LRPPARNGMCC.........YNSPAVILPMSEP..............................................
H0Y454_HUMAN/1-122             .x---------------------------.--------AWEANKFLT....PGLTHTM.ERH.VDPEAL.QKMAKCAVQDYTYRGSISGHPYLPEKYWLSQEE.....A......DK.......CSPNYLGS.......DWYNTWRMEPYNSScCNKYTTYLPRLPKVSVApSTDVWGLGHAYPT--------.......----------------------------------------------------..--------------.---------------...-----------.........-------------tsqttv........................................
#=GC seq_cons                  ..MFLFSRKTKTPISTYoDSYRAPTSIKE.VYKDPPLhAWEANKFlT....PGLTpTM.cRH.VDPEAL.QKMsKCAsQDYoY+uSIsGHPYLPEKYWLSp-E.....t......DK.......CsPsYLsu.......DRYNTWRhuPYNsosWNKYTThLPRLPKEAGM.ETsVRGMPL-hPPKPERLNAY.......EREVhVNMLNSLSRNQ.LPpIsPcCGCscsLPGRLPFpGY-SsCSGRHYCLR..GMDYhssGsPss-R.+Lpshs.pp.T.pss.......tRsshpC.........Ys.Pslhhsh.p...............................................
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