GenomeNet

Database: Pfam
Entry: SRI
LinkDB: SRI
Original site: SRI 
#=GF ID   SRI
#=GF AC   PF08236.6
#=GF DE   SRI (Set2 Rpb1 interacting) domain
#=GF AU   Mistry J, Wood V, Sammut SJ, Bateman A
#=GF SE   Pfam-B_106465 (release 17.0) & pdb_2a7o
#=GF GA   20.90 20.90;
#=GF TC   20.90 21.90;
#=GF NC   20.70 20.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   15798214
#=GF RT   A Novel Domain in Set2 Mediates RNA Polymerase II Interaction
#=GF RT   and Couples Histone H3 K36 Methylation with Transcript
#=GF RT   Elongation. 
#=GF RA   Kizer KO, Phatnani HP, Shibata Y, Hall H, Greenleaf AL, Strahl
#=GF RA   BD; 
#=GF RL   Mol Cell Biol 2005;25:3305-3316.
#=GF RN   [2]
#=GF RM   16314571
#=GF RT   Solution structure of the Set2-Rpb1 interacting domain of human
#=GF RT   Set2 and its interaction with the hyperphosphorylated C-terminal
#=GF RT   domain of Rpb1. 
#=GF RA   Li M, Phatnani HP, Guan Z, Sage H, Greenleaf AL, Zhou P; 
#=GF RL   Proc Natl Acad Sci U S A. 2005;102:17636-17641.
#=GF DR   INTERPRO; IPR013257;
#=GF CC   The SRI (Set2 Rpb1 interacting) domain mediates RNA polymerase
#=GF CC   II interaction and couples histone H3 K36 methylation with
#=GF CC   transcript elongation [1].  This domain is conserved from yeast
#=GF CC   to humans. Members of this family form a compact, closed
#=GF CC   three-helix bundle, with an up-down-up topology. The first and
#=GF CC   second helices are antiparallel to each other and are of similar
#=GF CC   length; the third helix, which is packed across helices alpha1
#=GF CC   and alpha2 is slightly shorter, consisting of only 15 amino
#=GF CC   acids. Most conserved hydrophobic residues are largely buried in
#=GF CC   the interior of the structure and form an extensive and
#=GF CC   contiguous hydrophobic core that stabilises the packing of the
#=GF CC   three-helix bundle. This domain mediates RNA polymerase II
#=GF CC   interaction and couples histone H3 K36 methylation with
#=GF CC   transcript elongation [2].
#=GF SQ   233
#=GS G5B1V2_HETGA/29-122     AC G5B1V2.1
#=GS Q5C1K8_SCHJA/64-169     AC Q5C1K8.2
#=GS SET2_USTMA/861-953      AC Q4PBL3.1
#=GS F6UMH0_CIOIN/183-277    AC F6UMH0.2
#=GS G3X921_MOUSE/1935-2029  AC G3X921.1
#=GS F2QLG8_PICP7/630-719    AC F2QLG8.1
#=GS Q177T5_AEDAE/2262-2357  AC Q177T5.1
#=GS F4RQ42_MELLP/789-877    AC F4RQ42.1
#=GS SET2_CANGA/623-713      AC Q6FX50.1
#=GS B4NCI2_DROWI/2117-2212  AC B4NCI2.1
#=GS G3HKR8_CRIGR/2313-2407  AC G3HKR8.1
#=GS G4VTQ6_SCHMA/542-647    AC G4VTQ6.1
#=GS G3SAD0_GORGO/2464-2558  AC G3SAD0.1
#=GS G1SIF6_RABIT/639-733    AC G1SIF6.1
#=GS H2UDT4_TAKRU/655-749    AC H2UDT4.1
#=GS F1MDT8_BOVIN/2439-2533  AC F1MDT8.2
#=GS B3RRG4_TRIAD/898-991    AC B3RRG4.1
#=GS A7TGR7_VANPO/598-688    AC A7TGR7.1
#=GS G2RAJ2_THITE/646-733    AC G2RAJ2.1
#=GS G3JMJ7_CORMM/664-752    AC G3JMJ7.1
#=GS B3NWN5_DROER/2284-2379  AC B3NWN5.1
#=GS E2LHR9_MONPE/106-160    AC E2LHR9.1
#=GS G0VKC2_NAUCC/631-721    AC G0VKC2.1
#=GS SET2_CANAL/718-813      AC Q59XV0.1
#=GS E3QCJ3_COLGM/648-736    AC E3QCJ3.1
#=GS F8MMU9_NEUT8/659-746    AC F8MMU9.1
#=GS H2KPL3_CLOSI/604-710    AC H2KPL3.1
#=GS Q0CA53_ASPTN/707-794    AC Q0CA53.1
#=GS SET2_CRYNJ/635-725      AC P0CO28.1
#=GS F0UF04_AJEC8/700-787    AC F0UF04.1
#=GS F6YTP3_HORSE/2440-2534  AC F6YTP3.1
#=GS F2PTV8_TRIEC/692-779    AC F2PTV8.1
#=GS B4Q2B7_DROYA/2297-2392  AC B4Q2B7.1
#=GS F8PMT5_SERL3/570-659    AC F8PMT5.1
#=GS SET2_SCHPO/690-781      AC O14026.1
#=GS D5GEI8_TUBMM/683-774    AC D5GEI8.1
#=GS F6X8U6_CALJA/2369-2463  AC F6X8U6.1
#=GS F4WGJ7_ACREC/1744-1838  AC F4WGJ7.1
#=GS F1NTN0_CHICK/1970-2064  AC F1NTN0.1
#=GS G3Y4Q1_ASPNA/702-789    AC G3Y4Q1.1
#=GS A6QZY7_AJECN/256-345    AC A6QZY7.1
#=GS E7LW72_YEASV/623-713    AC E7LW72.1
#=GS G7E366_MIXOS/767-859    AC G7E366.1
#=GS B4M386_DROVI/2001-2096  AC B4M386.1
#=GS SET2_EMENI/722-809      AC Q5ASA5.1
#=GS B3MWN1_DROAN/2315-2409  AC B3MWN1.1
#=GS E3SA89_PYRTT/697-785    AC E3SA89.1
#=GS A7EP40_SCLS1/679-766    AC A7EP40.1
#=GS A8PW19_BRUMA/1356-1442  AC A8PW19.1
#=GS F1R4G3_DANRE/409-503    AC F1R4G3.1
#=GS H0XG77_OTOGA/2433-2527  AC H0XG77.1
#=GS B8MDN7_TALSN/688-775    AC B8MDN7.1
#=GS G8BN76_TETPH/612-702    AC G8BN76.1
#=GS C4Y9S1_CLAL4/626-714    AC C4Y9S1.1
#=GS E9GMT3_DAPPU/1310-1404  AC E9GMT3.1
#=GS A5DE17_PICGU/598-686    AC A5DE17.2
#=GS G3WAZ3_SARHA/2467-2561  AC G3WAZ3.1
#=GS C6HSS4_AJECH/237-327    AC C6HSS4.1
#=GS H6C6N2_EXODN/705-792    AC H6C6N2.1
#=GS G8ZYV1_TORDC/594-684    AC G8ZYV1.1
#=GS E2RMP9_CANFA/1963-2057  AC E2RMP9.1
#=GS H3AEJ3_LATCH/2444-2536  AC H3AEJ3.1
#=GS SET2_KLULA/610-698      AC Q6CXP5.1
#=GS F1QJI9_DANRE/2638-2732  AC F1QJI9.1
#=GS C4JMW4_UNCRE/697-784    AC C4JMW4.1
#=GS C4YKT8_CANAW/720-815    AC C4YKT8.1
#=GS C7GRZ6_YEAS2/623-713    AC C7GRZ6.1
#=GS B4LGJ8_DROVI/1907-2001  AC B4LGJ8.1
#=GS C1H221_PARBA/685-758    AC C1H221.1
#=GS B4L0B7_DROMO/1873-1968  AC B4L0B7.1
#=GS E9C6H5_CAPO3/799-884    AC E9C6H5.1
#=GS SET2_ASHGO/593-681      AC Q757Y8.1
#=GS H2PAW9_PONAB/1961-2055  AC H2PAW9.1
#=GS D2GV98_AILME/2436-2530  AC D2GV98.1
#=GS G1MDY4_AILME/162-253    AC G1MDY4.1
#=GS SET2_NEUCR/659-746      AC Q7RZU4.1
#=GS A7RXF0_NEMVE/74-166     AC A7RXF0.1
#=GS E9EU13_METAR/651-739    AC E9EU13.1
#=GS H9MB98_PINRA/1-86       AC H9MB98.1
#=GS B2AWM9_PODAN/652-739    AC B2AWM9.1
#=GS C5E179_ZYGRC/587-678    AC C5E179.1
#=GS E9IEB7_SOLIN/1720-1814  AC E9IEB7.1
#=GS Q69ZC0_MOUSE/605-699    AC Q69ZC0.1
#=GS Q9LW25_ARATH/178-265    AC Q9LW25.1
#=GS B9WCT7_CANDC/709-800    AC B9WCT7.1
#=GS H9FTE9_MACMU/2466-2560  AC H9FTE9.1
#=GS D4A5H6_RAT/2195-2289    AC D4A5H6.1
#=GS F8NLQ5_SERL9/574-663    AC F8NLQ5.1
#=GS SET2_ASPFU/695-782      AC Q4WTT2.1
#=GS B0Y3A9_ASPFC/695-782    AC B0Y3A9.1
#=GS H9K0B4_APIME/1258-1352  AC H9K0B4.1
#=GS G8Y7C0_PICSO/631-719    AC G8Y7C0.1
#=GS F7VYB6_SORMK/612-699    AC F7VYB6.1
#=GS H0GII5_9SACH/623-713    AC H0GII5.1
#=GS G7NXW5_MACFA/2244-2338  AC G7NXW5.1
#=GS H0VBU8_CAVPO/1960-2054  AC H0VBU8.1
#=GS Q29G04_DROPS/2818-2913  AC Q29G04.2
#=GS E9E541_METAQ/651-739    AC E9E541.1
#=GS D8QZZ1_SELML/1202-1287  AC D8QZZ1.1
#=GS F7HU66_MACMU/2244-2338  AC F7HU66.1
#=GS F9X4Z5_MYCGM/602-689    AC F9X4Z5.1
#=GS E4UU96_ARTGP/691-778    AC E4UU96.1
#=GS F0XSU3_GROCL/711-798    AC F0XSU3.1
#=GS G0T0K3_RHOG2/693-781    AC G0T0K3.1
#=GS G2YH62_BOTF4/680-767    AC G2YH62.1
#=GS G7XSK3_ASPKW/703-790    AC G7XSK3.1
#=GS C5M534_CANTT/676-764    AC C5M534.1
#=GS D4ARY8_ARTBC/692-779    AC D4ARY8.1
#=GS SETD2_HUMAN/2465-2559   AC Q9BYW2.3
#=GS SETD2_HUMAN/2465-2559   DR PDB; 2A7O A; 13-107;
#=GS D6WL79_TRICA/1470-1564  AC D6WL79.1
#=GS F2Z317_HUMAN/2465-2559  AC F2Z317.2
#=GS A9V3J3_MONBE/630-731    AC A9V3J3.1
#=GS D7LRA3_ARALL/179-266    AC D7LRA3.1
#=GS H3DM25_TETNG/647-741    AC H3DM25.1
#=GS H9J0S0_BOMMO/263-357    AC H9J0S0.1
#=GS C5P7L6_COCP7/698-785    AC C5P7L6.1
#=GS E9CTN6_COCPS/659-746    AC E9CTN6.1
#=GS G9NUF8_HYPAI/662-750    AC G9NUF8.1
#=GS G9N392_HYPVG/659-747    AC G9N392.1
#=GS G2WGK5_YEASK/623-713    AC G2WGK5.1
#=GS C0NDT8_AJECG/700-787    AC C0NDT8.1
#=GS E6R923_CRYGW/634-723    AC E6R923.1
#=GS H8X476_9ASCO/667-755    AC H8X476.1
#=GS D4D4R9_TRIVH/692-779    AC D4D4R9.1
#=GS E7R3E0_PICAD/604-692    AC E7R3E0.1
#=GS E7QGC2_YEASZ/623-682    AC E7QGC2.1
#=GS I1C6I1_RHIO9/580-669    AC I1C6I1.1
#=GS Q0V466_PHANO/696-784    AC Q0V466.1
#=GS G7YHS2_CLOSI/649-736    AC G7YHS2.1
#=GS G5ANQ9_HETGA/421-515    AC G5ANQ9.1
#=GS H0EJU8_GLAL7/591-677    AC H0EJU8.1
#=GS SET2_CHAGB/603-683      AC Q2H988.1
#=GS SET2_YARLI/605-688      AC Q6C5G5.1
#=GS C0RXX6_PARBP/697-784    AC C0RXX6.1
#=GS C1G685_PARBD/697-770    AC C1G685.1
#=GS C8ZAZ6_YEAS8/623-713    AC C8ZAZ6.1
#=GS A3LU80_PICST/619-707    AC A3LU80.2
#=GS A8NJ83_COPC7/650-739    AC A8NJ83.2
#=GS B4IGT0_DROSE/145-240    AC B4IGT0.1
#=GS Q6PCY9_MOUSE/638-732    AC Q6PCY9.1
#=GS Q8K0F3_MOUSE/318-412    AC Q8K0F3.1
#=GS G2X7E5_VERDV/649-737    AC G2X7E5.1
#=GS B3LPV5_YEAS1/623-713    AC B3LPV5.1
#=GS SET2_GIBZE/785-873      AC Q4IB50.1
#=GS F2RN17_TRIT1/692-779    AC F2RN17.1
#=GS Q4RI17_TETNG/1492-1587  AC Q4RI17.1
#=GS D8TC03_SELML/1202-1287  AC D8TC03.1
#=GS F2SMP3_TRIRC/691-778    AC F2SMP3.1
#=GS G7MIS1_MACMU/2244-2338  AC G7MIS1.1
#=GS H2UDT3_TAKRU/2288-2382  AC H2UDT3.1
#=GS G2QBP9_THIHA/650-737    AC G2QBP9.1
#=GS D4AA96_RAT/2436-2530    AC D4AA96.1
#=GS G4MUF3_MAGO7/654-741    AC G4MUF3.1
#=GS H2QMH8_PANTR/2436-2530  AC H2QMH8.1
#=GS G3P1H7_GASAC/637-731    AC G3P1H7.1
#=GS C5K0U3_AJEDS/559-646    AC C5K0U3.1
#=GS G5CAT1_HETGA/325-418    AC G5CAT1.1
#=GS H9G639_ANOCA/2481-2575  AC H9G639.1
#=GS G8BJV0_CANPC/670-758    AC G8BJV0.1
#=GS G1MV76_MELGA/2417-2511  AC G1MV76.2
#=GS G8JX28_ERECY/591-679    AC G8JX28.1
#=GS H0YPH4_TAEGU/2461-2524  AC H0YPH4.1
#=GS B6K1E8_SCHJY/654-745    AC B6K1E8.1
#=GS E0VVJ9_PEDHC/1348-1442  AC E0VVJ9.1
#=GS A1CZG9_NEOFI/695-782    AC A1CZG9.1
#=GS F9G813_FUSOF/644-732    AC F9G813.1
#=GS G3UV50_MELGA/626-720    AC G3UV50.1
#=GS A5DYF1_LODEL/674-762    AC A5DYF1.1
#=GS E1FRX0_LOALO/1329-1415  AC E1FRX0.1
#=GS B4J2R7_DROGR/1960-2054  AC B4J2R7.1
#=GS G1XCW9_ARTOA/707-791    AC G1XCW9.1
#=GS G3UYE0_MOUSE/661-755    AC G3UYE0.1
#=GS B0D7G3_LACBS/676-762    AC B0D7G3.1
#=GS A0NGT7_ANOGA/2299-2394  AC A0NGT7.2
#=GS B8NSI5_ASPFN/689-776    AC B8NSI5.1
#=GS SET2_DEBHA/622-710      AC Q6BM04.2
#=GS C5FVL3_ARTOC/688-775    AC C5FVL3.1
#=GS C5DKG6_LACTC/596-684    AC C5DKG6.1
#=GS H9WGG1_PINTA/1-86       AC H9WGG1.1
#=GS B6QGD6_PENMQ/697-784    AC B6QGD6.1
#=GS G4UQ54_NEUT9/659-746    AC G4UQ54.1
#=GS F2TIW0_AJEDA/700-787    AC F2TIW0.1
#=GS C5GXS6_AJEDR/559-646    AC C5GXS6.1
#=GS C4QY01_PICPG/630-719    AC C4QY01.1
#=GS G1R333_NOMLE/2436-2530  AC G1R333.1
#=GS E2LHR9_MONPE/52-95      AC E2LHR9.1
#=GS E3WZW3_ANODA/2527-2622  AC E3WZW3.1
#=GS A1C9T9_ASPCL/696-783    AC A1C9T9.1
#=GS G1M2A2_AILME/2441-2535  AC G1M2A2.1
#=GS I1RNH8_GIBZE/670-750    AC I1RNH8.1
#=GS F6UQE2_MONDO/1983-2077  AC F6UQE2.1
#=GS A6ZQG4_YEAS7/623-713    AC A6ZQG4.1
#=GS B4H7D3_DROPE/3-65       AC B4H7D3.1
#=GS B7QG36_IXOSC/1492-1586  AC B7QG36.1
#=GS A9NXI7_PICSI/401-488    AC A9NXI7.1
#=GS C7YYN9_NECH7/656-744    AC C7YYN9.1
#=GS F1KR78_ASCSU/855-943    AC F1KR78.1
#=GS G0S676_CHATD/653-741    AC G0S676.1
#=GS SET2_YEAST/623-713      AC P46995.2
#=GS SET2_YEAST/623-713      DR PDB; 2C5Z A; 623-713;
#=GS B4R4C9_DROSI/2148-2243  AC B4R4C9.1
#=GS E5A0B0_LEPMJ/724-812    AC E5A0B0.1
#=GS SET2_COCIM/690-777      AC Q1DU03.1
#=GS G3AM54_SPAPN/605-693    AC G3AM54.1
#=GS SET2_ASPOR/707-794      AC Q2UTN6.1
#=GS Q071D9_DANRE/270-364    AC Q071D9.1
#=GS E6ZVI7_SPORE/848-941    AC E6ZVI7.1
#=GS H9IAB6_ATTCE/1739-1833  AC H9IAB6.1
#=GS C3YEA6_BRAFL/254-347    AC C3YEA6.1
#=GS E9Q5F9_MOUSE/2438-2532  AC E9Q5F9.1
#=GS F4P7F7_BATDJ/1263-1351  AC F4P7F7.1
#=GS E3KF80_PUCGT/725-811    AC E3KF80.2
#=GS F2UKY3_SALS5/828-922    AC F2UKY3.1
#=GS H2YKZ5_CIOSA/84-178     AC H2YKZ5.1
#=GS A6SPE7_BOTFB/680-767    AC A6SPE7.1
#=GS G0RRY8_HYPJQ/667-755    AC G0RRY8.1
#=GS I1CM29_RHIO9/751-835    AC I1CM29.1
#=GS I1CSD0_RHIO9/803-882    AC I1CSD0.1
#=GS G3WAZ4_SARHA/2469-2563  AC G3WAZ4.1
#=GS G4T5A8_PIRID/651-739    AC G4T5A8.1
#=GS G3BBE8_CANTC/616-703    AC G3BBE8.1
#=GS B2W0G7_PYRTR/696-784    AC B2W0G7.1
#=GS C1716_DROME/2215-2310   AC Q9VYD1.2
#=GS B5VL18_YEAS6/623-713    AC B5VL18.1
#=GS C9SV17_VERA1/651-739    AC C9SV17.1
#=GS F1SNU6_PIG/640-734      AC F1SNU6.1
#=GS D8QG04_SCHCM/613-703    AC D8QG04.1
#=GS F7D163_XENTR/2440-2534  AC F7D163.1
#=GS SET2_CRYNB/635-725      AC P0CO29.1
#=GS G0W5J9_NAUDC/684-774    AC G0W5J9.1
#=GS H3HSC8_STRPU/2925-3019  AC H3HSC8.1
#=GS H2AWM4_KAZAF/597-687    AC H2AWM4.1
#=GS E1JJN9_DROME/2215-2310  AC E1JJN9.1
#=GS H1V2C6_COLHI/659-747    AC H1V2C6.1
G5B1V2_HETGA/29-122                ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKSdckvgriTTTED...FKH.L.AQKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVK-QNQGVHKEVHAEVWGCLQT--qr.....
Q5C1K8_SCHJA/64-169                ..............aPQDVAEQGFAI..ELFTLVHNTLRSFRDArcklgriVNDED...LYY.L.TKKLAQAVILK.E.IQkfhqtqaANTs..lfSTVLTPELPS......TVRSRVTAYVRRYMESKGAFYRRR-v......
SET2_USTMA/861-953                 ..............eSVAANERRLRK..LVGELVVRQMSKYKDD.......LERES...FKR.H.AKELTNAIVGK.E.MRnp...ksWPP.....ARGALTELSL......DKRAKIKAFAKEYIDKLLARKGK--gk.....
F6UMH0_CIOIN/183-277               ..............eEAKKAREAFRS..KMSQHIVYCLNSYRKPeckigriTSTED...FKR.L.ARKLTHNVLMK.E.IK.......QVI.....-VWEDLEYNA......NVKHKAKEYVKKYMAKMGPIYKAR-d......
G3X921_MOUSE/1935-2029             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
F2QLG8_PICP7/630-719               ..........kskrp---TREQEWNK..LFATVVPNMIKKHESQ.......IGRDN...LKH.C.AKDIVHQLSSK.E.IK.......KDT.....SKKPPKELSS......EKKAKVKAFVGPYMEKYLDKWKAKH.......
Q177T5_AEDAE/2262-2357             ..............dEARKIKEKFRG..EIAGVIVQHLGAYRKDscqtgriTNTED...FKH.L.ARKLTHFVLVK.E.LK.......HCD.....NTINELEVTD......SVRTKAREFIKKYMAKHGTIYVR--gd.....
F4RQ42_MELLP/789-877               .............ss-SQTKDKKMLR..LFSTVVVRTMSRYKDS.......LEHDQ...FKK.R.AKELTNILCQK.E.AK.......SSN....yMVDDYDKLTP......GKEAKIISFVKDWTAKLLARK----gla....
SET2_CANGA/623-713                 ..............sQISKMEHKWTK..FFASVVPNILKKYESDk.....kIDHDN...MKQ.C.ARDIVKILAAK.E.MK.......KDS.....SKEPEATVSK......EKRHKIKQFVHGYMEKFLEKLDKKK.......
B4NCI2_DROWI/2117-2212             ..............sSGREATEKFRF..AISGHVADFLRPYRKDncqfgriTCDED...YRF.L.IKRLSHHITTK.E.MR.......YCD.....LTGNPLACTE......SVKHKSYDFVNQYMRKKGCVYKKP-a......
G3HKR8_CRIGR/2313-2407             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
G4VTQ6_SCHMA/542-647               ..............aPQDVTEQGFAM..ELFTLVHNTLRGFRDArcklgriVNDED...LYY.L.TKKLAQAVILK.E.IQkfhqtqaANTs..lfSTVLTPELPS......TVRSRVTTYVRRYMESKGAFYRRR-v......
G3SAD0_GORGO/2464-2558             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
G1SIF6_RABIT/639-733               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
H2UDT4_TAKRU/655-749               ..............eLAKKSKETFRK..EMSQFIVQCLNPYRKPdcklgriSNTED...FKH.L.ARKLTHGVMNK.E.LK.......ACT.....-NPEDLECNE......NVKHKAKEYIKKYMQRFGSVYRPKE.......
F1MDT8_BOVIN/2439-2533             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
B3RRG4_TRIAD/898-991               .............id--KKVKEEFRQ..KITPTIIEHLNPYRKPdcktghiTSKED...FKA.L.ARKLSYGVLDK.E.TK.......RLK.....-PSESLRVTD......SVKHRIKNFIRQYMEKCGPVYEP--sk.....
A7TGR7_VANPO/598-688               ..............sRSSHIEHKWNK..FFASVVPNLLKKYENEh.....nISHEH...TKH.C.SREIVKILTSK.E.LK.......KDP.....SRAPDEEPTK......EKRAKIRDFTTIYMDKFIQKYQDKK.......
G2RAJ2_THITE/646-733               ..............lPIEKQMKIYEN..TLFPHVKHVMDKFHGK.......LPKED...LKK.F.AREVNKKLVAS.D.YK.......NNR.....VEDP-TSISS......KLAKKVRNYVQDFFERALVKYTEH-e......
G3JMJ7_CORMM/664-752               ..............lPQDKQMKIYEN..TLFPHIKHVLDKFRHK.......LPKDD...LKR.L.GKDLAKKLVAS.D.YK.......NGR.....VTDPTAKLSD......KQIYKIKTYAKDFLDRAVQKYA---vqk....
B3NWN5_DROER/2284-2379             ..............tSGREAHEKFRF..EISGHVADFLRPYRKEscqlgriTSDED...YKF.L.IKRLSHHITTK.E.VR.......YCD.....ITGNPLSCTE......SVKHKSYDFINQYMRKKGRVYRKP-a......
E2LHR9_MONPE/106-160               ............npl-----------..----------------.......-----...---.-.-RQLTEKIAER.E.KK.......SSA....yKEGKLDTLSD......EKTAKIKKYAKEYITTKILRK----vgks...
G0VKC2_NAUCC/631-721               ..............sQVNVSEHKWNK..FFASFVPNLVRKNVVGv.....kLSHDH...IKE.C.SRDIVKILTSK.E.LK.......KDD.....AKSPPEDLTR......EKKKKTNSFVKVYMEKFIEKYKSKK.......
SET2_CANAL/718-813                 ..............sSGNNVEKIWKR..IFAKYIPNIIKKYESE.......IGRDN...VKG.C.AKELVNILTQS.E.IKhgnslpsSSS.....SNGYSMELSD......KKLKKIKEYSHGYMDKFLIKFNNS-k......
E3QCJ3_COLGM/648-736               ..............lSTDKQMKIYEN..TLFPHVKYVIDKYRHK.......LPKDD...LKR.L.GKDVCKKLVSS.D.YK.......GKR.....VQDPTIPLDQ......KQARKVKTYVKDFLDKAIVKFK---hfe....
F8MMU9_NEUT8/659-746               ..............lPVEKQMKIYEN..TLFPHVKYVMDKFHRR.......LPKED...LKR.F.GREINKKLVAS.D.YK.......NHR.....VDDP-TTISS......NQARKIKKFVKDFFDRAVVKHREN-e......
H2KPL3_CLOSI/604-710               ...........apkg---AVEQGFAI..ELFTLVHDVLRNYRDArckvgriLNDED...LYY.L.TRKLAQAVIVK.E.VQkwrsdqaACAss.lfASAPIPELTA......SVNARVSTYVKRYMESKGAFYRRR-v......
Q0CA53_ASPTN/707-794               ..............ySEEKQKKLYEN..TLFPHVKYVVDKFKHK.......LPKED...LKR.Y.AKDVAKKLVNS.D.FK.......NNR.....VQDP-TRIDE......KQQKKVKKFCKEFFDKAVQKHRAH-e......
SET2_CRYNJ/635-725                 ..............eLAEQKERRLRK..LIGAVVVKSMNKYKDM.......MEHDT...FKK.Y.ARECTDTLVKK.E.KK.......RNPs...yQDVKHPSLSD......DKKAKIKSFTKDYTHKILKHLKEK-g......
F0UF04_AJEC8/700-787               ..............ySEEKQKKLYEN..TIFPHVKYVVDKFKHK.......LPKED...LKR.Y.AKEVGKKLVNS.D.FK.......NNR.....VSDP-TKVSD......KQVKQIKKYCKEYFDKAVVKQRA--ye.....
F6YTP3_HORSE/2440-2534             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
F2PTV8_TRIEC/692-779               ..............lSEEKQKKIYEN..TLFPHVKYVVDKFKNK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VTDP-TKVSE......KQIKQVKKFCKEYFEKAVVKHQA--ye.....
B4Q2B7_DROYA/2297-2392             ..............tSGREAHEKFRF..EISGHVADFLRPYRKEscqlgriTSDED...YKF.L.IKRLSHHITTK.E.VR.......YCD.....LTGNPLSCTE......SVKHKSYDFINQYMRKKGRVYRKP-a......
F8PMT5_SERL3/570-659               ..............eKEANKEKRLVK..LVGAIVVKCMSKHSKK.......MDHEQ...FKK.H.AKELTHIIAEK.E.KK.......SSS....yKDGKLDALSD......EKVTKIKKFSKEYIAKVLRKLEKT-k......
SET2_SCHPO/690-781                 ..............tSHSPESIAFKA..VLAKFFANKTARYQEK.......LGKAE...FKL.R.VKKMTEIILKK.H.IQl....vlSKK.....EKALPDELSD......SQQRKLRVWAFRYLDTVVSRSG---tat....
D5GEI8_TUBMM/683-774               .............yd-NEKTKKILIR..AFSTVVANAVNKYESE......iGGRDL...VKK.H.AKDITELLVKK.E.MK.......DGRq...iANPHLLLESD......SKRLKVKGFVKPYIEKVIRNKQ---smd....
F6X8U6_CALJA/2369-2463             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
F4WGJ7_ACREC/1744-1838             ..............mSERKIKDTFRI..NMANVMVHFLNPYRKNdckqgriTNTED...FKH.L.ARKLTHFVLAK.E.LK.......HCK.....-SVDELQCNE......NVKHKARDFVRKYMSKFGAVYQK--gt.....
F1NTN0_CHICK/1970-2064             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAIYKPK-e......
G3Y4Q1_ASPNA/702-789               ..............ySEEKRKKIYEN..TLYPHVKYVVDKFKHK.......LPKDD...LKR.Y.AKDVAKKLVNS.D.FK.......NNR.....VGDP-TKIDD......KQQKKVKKFCKEFFDKAVAKHRA--ye.....
A6QZY7_AJECN/256-345               ..............ySEEKQKKLYEN..TIFPHVKYVVDKFKHK.......LPKED...LKR.Y.AKEVGKKLVNS.D.FK.......NNR.....VSDP-TKVSD......KQVKQIKKYCKEYFDKAVVKQRA--yekk...
E7LW72_YEASV/623-713               ..............sQSQRLEHNWNK..FFASFVPNLIKKNPQSk.....qFDHEN...IKQ.C.AKDIVKILTTK.E.LK.......KDS.....SRAPPDDLTK......EKRHKVKEFINSYMDKIILKKKQKK.......
G7E366_MIXOS/767-859               .........kivdkd------TRVRK..LLGNYVVELFNKYRKNkt...lkLNDAE...FKK.Y.AKHITDAVFAK.E.KR.......SDK....yATTEYTKLPP......HKEKKVKEYVQSWIKRRHEE-----qkaqk..
B4M386_DROVI/2001-2096             ..............sSGREACEKFRF..EISGHVAEFLRPYRKDtchlgriTNDAD...YKF.L.IKRLSHHITTK.E.MR.......YCD.....LIGNPLACTE......SVKHKSYEFINQYMRKKGRVYRKP-a......
SET2_EMENI/722-809                 ..............ySEEKQKKLYEN..TLYPHIKYVVDKFKHK.......LPKDD...LKR.Y.AKDVAKKLVNS.D.FK.......NNR.....VTDP-TKIDD......KQQKKVKKFCKEFFDKAVAKHQAH-e......
B3MWN1_DROAN/2315-2409             .............gg--REAHDKFRF..EISGHVAEFLRPYRKDscqlgriTSDED...YKF.L.IKRLSHHITTK.E.MR.......YCD.....MTGNPLACTE......SVKHKSYDFINQYMRKKGRVYRKP-a......
E3SA89_PYRTT/697-785               ............lti--EKQEKVYEA..TIAPYIMSTANLYSKK.......LEKEE...FKS.L.CKEVAKKVVRG.D.YK.......NGP.....VKDPTAKIPP......NHQKRIKNCVHEYMNKAVKTAEER-r......
A7EP40_SCLS1/679-766               ............lpl--EKQMKLYEN..TLFPHIKHVMQKYSGK.......LPKDD...LKK.F.AKECGKKLVAS.D.FK.......NNR.....VEDP-TKISE......KHEKKVKKYVRDYFEKAVQKKKEM-e......
A8PW19_BRUMA/1356-1442             ..........tidtr------ATFKA..EIVKYVGGMLEPIRKLk.....fASADD...YKY.V.LRKLTHTILEK.E.LK.......RVG.....--ETELKVTE......SVRDKARKFVAEYLARLG-------dgqysrk
F1R4G3_DANRE/409-503               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdcklgriSNTED...FKH.L.ARKLTHGVMNK.E.LK.......SCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGSVYRPKE.......
H0XG77_OTOGA/2433-2527             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
B8MDN7_TALSN/688-775               ..............yPEEKQKKIYEN..TIHPYVKYVVDKFKKK.......LPKED...LKR.Y.AKEVATKLVDS.D.FK.......HGR.....VEDI-LQISE......KQQQKIKKYCKEYFEKAVAKHKAH-e......
G8BN76_TETPH/612-702               ..............nKQEVLEHKWNK..YFATFVPNILKKYKDQh.....nLSHDH...IKN.C.ARDIVKTLTAK.E.LK.......KNA.....DKTPPEKPSS......EKLAKVKSFVKGYMEKFIIKYNEKK.......
C4Y9S1_CLAL4/626-714               ..............sSKVSIETLWTK..TLAKYIPNMIKKYEAD.......IGHEN...IKG.C.ARELVKILAGK.E.TK.......KAP.....DTKPPRELDN......AKLKKLKEFSKSFMEKFLVKYRAK-r......
E9GMT3_DAPPU/1310-1404             .............nt-VRKIKDAFRM..KISSDIVNILNPYRRPdcklgriTCTDD...FKH.L.ARKMTHFVLAK.E.LK.......HCR.....-NIQDLVVND......SVKHKAKDFIKKYMAKFGPAYKR--gn.....
A5DE17_PICGU/598-686               .............dn-NVSIEQQWAK..LFAKHIPNMIKKHEKT.......IGHDN...VKG.C.AKDLVKILASK.E.IK.......KHP.....DTAPPTELDR......AKLKKIKEFSSMFMDKFLQKYEAK-r......
G3WAZ3_SARHA/2467-2561             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGTVYKPKE.......
C6HSS4_AJECH/237-327               ..............ySEEKQKKLYEN..TIFPHVKYVVDKFKHK.......LPKED...LKR.Y.AKEVGKKLVNS.D.FK.......NNR.....VSDP-TKVSD......KQVKQIKKYCKEYFDKAVVKQRA--yekkk..
H6C6N2_EXODN/705-792               .............yn-EEKQKKLYEN..TLFPLISHVMNKYKNK.......IPRDD...LKR.F.AKEVAKKLVAS.D.YK.......AGR.....VKDP-TKIEE......KQQKKVKEFCKQFFEKAYQKHKKH-e......
G8ZYV1_TORDC/594-684               ..............sQTNHVEHKWNK..FFASLVPNLLRKYEHDk.....qISHDS...AKQ.C.ARDIVKILTSK.E.LK.......KDV.....TRSPPDEPTK......EKRAKVKQFTQSYMEKILQKKKS--rs.....
E2RMP9_CANFA/1963-2057             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
H3AEJ3_LATCH/2444-2536             .............el-AKKSKEVFRK..EVRHWVVFFINSFLFPsc...trIAFSS...FCLlL.HAQLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAIYKPK-e......
SET2_KLULA/610-698                 ..............sHVNAIENKWVK..FFAQHVPNLIKNYQKD.......VGKDV...LKE.S.ARNIVKSLAQK.E.LK.......KDS.....SRSPPEELSK......EKRAKVKTFSMQYMDRLVAKMKEKK.......
F1QJI9_DANRE/2638-2732             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdcklgriSNTED...FKH.L.ARKLTHGVMNK.E.LK.......SCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGSVYRPKE.......
C4JMW4_UNCRE/697-784               ..............ySEEKRKKLYEN..TLFPHVKYIVDKFKHK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VQDP-TKISE......KQIKQVKKYCKEYFDKAVSKHRAH-e......
C4YKT8_CANAW/720-815               ..............sSGNNVEKIWKR..IFAKYIPNIIKKYESE.......IGRDN...VKG.C.AKELVNILTQS.E.IKhgnslpsSSS.....SNGYSMELSD......KKLKKIKEYSHGYMDKFLIKFNNS-k......
C7GRZ6_YEAS2/623-713               ..............sQSQRLEHNWNK..FFASFVPNLIKKNPQSk.....qFDHEN...IKQ.C.AKDIVKILTTK.E.LK.......KDS.....SRAPPDDLTK......EKRHKVKEFINSYMDKIILKKKQKK.......
B4LGJ8_DROVI/1907-2001             .............tg--RDASDKFHF..EISGHVAEFLRPYRQDtcqlgriTSDED...YKF.L.IKRLSHHITTK.E.MR.......YCD.....MTGNPLACTE......SVKHKSYEFIKQYMRKKGPVYKK--pv.....
C1H221_PARBA/685-758               ...........ppei-----------..----------KEHKEKw....rsYSEEK...QKR.LyENTVGKKLVNS.D.FK.......NHR.....VDDP-TKVSD......KQIKQIKRYCKEYFDKAVAKH----laye...
B4L0B7_DROMO/1873-1968             .............tt-GREASDKFHF..EISGHVAEFLRPYRQEncqlgriTSDED...YKF.L.IKRLSHHITTK.E.MR.......YCD.....MTGNPLACTE......SVKHKSYDFIKQYMRKKGPVYKK--pv.....
E9C6H5_CAPO3/799-884               ....hrvsktrefkk-----------..-------KALSPYFKPactqgriTSKED...FKH.L.AGKLVKLIIEK.E.RK.......KLT.....DNEASLVLDE......AVTKRAKLFVTKYMSAFDAEY----tr.....
SET2_ASHGO/593-681                 ..............hSASRIEHKWNK..FFAQIVPNLIKSYATS.......MDRAR...IKE.C.ARDIVKILSSK.E.LK.......KDA.....TKVPPAEVTK......EKRKKVNEFCKSYMDKLLAKMHEK-a......
H2PAW9_PONAB/1961-2055             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
D2GV98_AILME/2436-2530             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
G1MDY4_AILME/162-253               ..............eLAKKSKEVFRE..EVLQFIVQGLNPYWKPdck.merITTEV...FKH.L.AHKRTHGVTEK.-.LK.......YCK.....--PEDLECNE......NVKHETKEYVKKYMHKTGAVYKLK-k......
SET2_NEUCR/659-746                 ..............lPVEKQMKIYEN..TLFPHVKYVMDKFHRR.......LPKED...LKR.F.GREINKKLVAS.D.YK.......NHR.....VDDP-TTISS......NQARKIKKFVKDFFDRAVVKHREN-e......
A7RXF0_NEMVE/74-166                .............ak--QKIKDAFRV..KLSNVVVNCLNPYHKVdckqgriTNVED...FKY.L.ARKLTHGVMMK.E.LQ.......HVK.....-SAESLQCND......SVKVKTKDYIRSYMKKFGPVYQR--t......
E9EU13_METAR/651-739               ..............lPIEKQMKIYEN..TVFPPVKHMLDKFRHR.......LPKEE...LKR.L.GKDIAKKLVAS.D.YK.......NNR.....VEDPTAALSE......KQTLKIKKHVKDFLTRAVEKYE---vhq....
H9MB98_PINRA/1-86                  .............ds---RSMKLFRS..ALAEFVKEALKPSWREg.....hMSKEA...FKT.I.VKKAVDKVAG-.A.MQ.......NHQi..pkSRGRIDQYVA......SSERKLTKLVQGYVDKYVR------v......
B2AWM9_PODAN/652-739               ..............lPIEKQMKIYEN..TLFPHVKYVVEKFHGK.......LPKED...LKK.F.AREVNKKLVSS.D.YK.......NNR.....VEDP-THISS......KQEKKVKKYVRDFFDRAVVKYKEQ-q......
C5E179_ZYGRC/587-678               ............kkk-NHHLEHKWDK..FFASFVPGLLRRYEQNe.....gLSHDH...AKQ.C.ARDIVKILTSK.E.LK.......KDV.....TKPPPEEPSK......DKRAKVKQFTASYMDKFLIKYKKKH.......
E9IEB7_SOLIN/1720-1814             ..............mSERKIKDTFRI..NMANVMVHFLNPYRKIdckqgriTNTED...FKH.L.ARKLTHFVLAK.E.LK.......HCK.....-SVDELQCND......NVKHKARDFVRKYMSKFGAVYQK--gt.....
Q69ZC0_MOUSE/605-699               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
Q9LW25_ARATH/178-265               .............rd-SSRSMKLFKV..VLTKFVKDLLKPSWRQg.....nMSKEA...FKT.I.VKRVVDKVSNSmE.GR......rIPK.....SRAKIDKYID......SSQQKLTKLVMGYVDKYVK------a......
B9WCT7_CANDC/709-800               ...........sgsg---NIEKTWKR..IFAKYIPNIIKKYESE.......IGRDN...VKG.C.ARELVNVLTQS.E.IKh....gkKPP.....SNDSNMELND......KKLKKIKEYSYRYMDKFLIKFNNS-k......
H9FTE9_MACMU/2466-2560             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
D4A5H6_RAT/2195-2289               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
F8NLQ5_SERL9/574-663               ..............eKEANKEKRLVK..LVGAIVVKCMSKHSKK.......MDHEQ...FKK.H.AKELTHIIAEK.E.KK.......SSS....yKDGKLDALSD......EKVTKIKKFSKEYIAKVLRKLEKT-k......
SET2_ASPFU/695-782                 ..............ySEEKQKKLYEN..TLFPHIKYVVDKFKHK.......LPKED...LKR.Y.AKDVAKKLVNS.D.FK.......NNR.....VEDP-TKISE......KQQKKVKAFCKEFFDKAVAKHRA--ye.....
B0Y3A9_ASPFC/695-782               ..............ySEEKQKKLYEN..TLFPHIKYVVDKFKHK.......LPKED...LKR.Y.AKDVAKKLVNS.D.FK.......NNR.....VEDP-TKISE......KQQKKVKAFCKEFFDKAVAKHRA--ye.....
H9K0B4_APIME/1258-1352             ..............mSERKIKDTFRI..NMANVMVHFLNPYRKNdckqgriTNTED...FKH.L.ARKLTHFVLAK.E.LK.......HCK.....-SVDELQCNE......NVKHKAKDFVRKYMSKFGAVYQKS-t......
G8Y7C0_PICSO/631-719               ..............sSEVSLEQQWTK..LFANYVPNLIKKFEAE.......VGRDN...IKG.C.ARELVKTLTEK.E.LK.......KHP.....DTKAPKELDS......AKLKKIKEYCRAFMDKFLIKYKAKH.......
F7VYB6_SORMK/612-699               ..............lPIEKQMKIYEN..TLFPHVKYVMDKFHRR.......LPKED...LKR.F.GREINKKLVAS.D.YK.......NHR.....VDDP-TTISS......HQARKIRKFVKEFFDRAVVKHREN-e......
H0GII5_9SACH/623-713               ..............sQSQRLEHNWNK..FFASFVPNLIKKNPQSk.....qFDNEN...IKQ.C.AKDIVKILTTK.E.LK.......KDS.....SRAPPDDLTK......EKRHKVKEFINSYMDKIILKKKQKK.......
G7NXW5_MACFA/2244-2338             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
H0VBU8_CAVPO/1960-2054             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
Q29G04_DROPS/2818-2913             ..............kSGRDSVVKFRF..EISGHVADFLRPFRKDscqmgriTSDAA...YKF.L.IKRLTEHIITK.E.MR.......YCE.....MSGHPLICND......SVKHKSHEFINQYMLKKGRVYVM--pa.....
E9E541_METAQ/651-739               ..............lPIEKQMKIYEN..TVFPPVKHMLDKFRHK.......LPKEE...LKR.L.GKDIAKKLVAS.D.YK.......NNR.....VEDPTAALSE......KQTLKIKKYVKDFLTRAVEKYE---vhq....
D8QZZ1_SELML/1202-1287             ..........tpdqi---------KK..ALSEYVVHLLTPLYKTr.....kIQKDA...FKA.I.AKKTTMKVMER.D.GI.......RDT.....DVNISDYLNG......KRKNKIRELVDKFVEKHLAETKQ--sa.....
F7HU66_MACMU/2244-2338             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
F9X4Z5_MYCGM/602-689               ..............lPEEKQKKLYEG..TLSPHIMHVVAKYKHK.......LPKDE...LKR.W.AKEFAKQVVDS.D.FR.......KNK.....VADP-NKIDD......KKIKDVRKHAQTFFEKAVKKKQAA-e......
E4UU96_ARTGP/691-778               ..............lSEEKQKKLYEN..TLFPHVKYVVDKFKNK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VTDP-TKVSE......KQIKQVKKFCKEYFEKAVVKHQA--ye.....
F0XSU3_GROCL/711-798               ..............yPIEKQMRIYEN..TLSPHIRSVSDRYRHR.......LPKDE...LKK.L.AKDISKKLVAS.D.YK.......NNR.....VEDP-TAISP......RVEKKVKTYVRDFFDRAVTKYGEH-e......
G0T0K3_RHOG2/693-781               ....tgemqrervmg-----------..LFSNVVVATMSKYKAH.......FDSET...FKK.R.AREVTEILIEK.E.KK.......RPS....yESEAYDSLAP......EKESKVNSFVKEWVKKLLERRK---sss....
G2YH62_BOTF4/680-767               ..............lPIEKQMKLYEN..TLFPHIKHVMQKYSGK.......LPKDD...LKK.F.AKECGKKLVAS.D.FK.......NNR.....IEDP-TKISD......RNQRKVKQYVFEYFKKAVEKKREM-d......
G7XSK3_ASPKW/703-790               ..............ySEEKRKKIYEN..TLYPHVKYVVDKFKHK.......LPKDD...LKR.Y.AKDVAKKLVNS.D.FK.......NNR.....VGDP-TKIDD......KQQKKVKKFCKEFFDKAVVKHRA--ye.....
C5M534_CANTT/676-764               .............ld-VKKVEKQWKY..LLAKHIPNYLKKYESE.......IGKDN...IKG.C.AKELVATVTRG.E.MK.......LNP.....TSPAPVELDS......KRLQKIKQLTHDYMEKFMNKYRSKK.......
D4ARY8_ARTBC/692-779               ..............lSEEKQKKIYEN..TLFPHVKYVVDKFKNK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VTDP-TKVSE......KQIKQVKKFCKEYFEKAVVKHQA--ye.....
SETD2_HUMAN/2465-2559              ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
#=GR SETD2_HUMAN/2465-2559   SS    ..............HHHHHHHHHHHH..HHHHHHHHHHTTTSSTT-SSSB---HHH...HHH.H.HHHHHHHHHHH.H.HH.......HH-.....--GGG-S--H......HHHHHHHHHHHHHHTTT-SB--GGG.......
D6WL79_TRICA/1470-1564             .............et-AKKVKEVFRS..NMATVVVSVLNAYRKPdckegriTNTDD...FKH.L.ARKLTHFVMLK.E.MK.......HIE.....-KIDDLVCTE......NVKAKAKEYIRKYMSKFGENYQKR-n......
F2Z317_HUMAN/2465-2559             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
A9V3J3_MONBE/630-731               .............sk-RKARLNKFKS..EVSERVIKQLNAYREKkvkygyiRTSED...FKY.L.ARKLTHKIVEK.E.LQ.......RRG.....QDVNELVMTDglkgkaSTRMHIKNFITDTMKKCGKVFRQ--pa.....
D7LRA3_ARALL/179-266               .............rd-SSRSMKLFKV..VLTKFVKDLLKPSWRQg.....nMSKEA...FKT.I.VKRVVDKVSNSmEgHR.......IPK.....SRAKIDRYID......SSQQKLTKLVMGYVDKYVK------a......
H3DM25_TETNG/647-741               .......lgvlnldf--------FHSyhRMSQFIVQCLNPYRKPdcksgriSNTED...FKH.L.ARKLTHGVMNK.E.LK.......ACT.....-NPEDLECN-......NVKHKAKEYIKKYMQRFGSVYRPKE.......
H9J0S0_BOMMO/263-357               .............et-SRRIKEQFRS..AMAGVMVQHLNPYRHSdapagriTCTAD...FKH.L.ARKLTHFVMLK.E.LK.......HCR.....-SVEELVVTD......SVRSKAKTFVKKYMAKFGPVYKR--pp.....
C5P7L6_COCP7/698-785               ..............ySEEKQKKLYEN..TLFPHVKYIVDKFKHK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VEDP-TKISE......KQIKQVKKYCKEYFDKAVAKHRA--ye.....
E9CTN6_COCPS/659-746               ..............ySEEKQKKLYEN..TLFPHVKYIVDKFKHK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VEDP-TKISE......KQIKQVKKYCKEYFDKAVAKHRA--ye.....
G9NUF8_HYPAI/662-750               ..............lPVEKQMKLYEH..TVYPPVKHVLDKFRHK.......LPKDE...LKR.L.GKDVAKKLVAS.D.YK.......NNR.....VSDPAAPLTE......KQERNIKKYVKDFLDRAVSKYEAH-h......
G9N392_HYPVG/659-747               ..............lPVEKQMKVYEH..TVYPPVKHVLDKFRHK.......LPKEE...LKR.L.GKDVAKKLVTS.D.YK.......NNR.....VNDPAAPLTE......KQERNIKKYVKDFLDRAVAKYEAH-h......
G2WGK5_YEASK/623-713               ..............sQSQRLEHNWNK..FFASFVPNLIKKNPQSk.....qFDHEN...IKQ.C.AKDIVKILTTK.E.LK.......KDS.....SRAPPDDLTK......EKRHKVKEFINSYMDKIILKKKQKK.......
C0NDT8_AJECG/700-787               ..............ySEEKQKKLYEN..TIFPHVKYVVDKFKHK.......LPKED...LKR.Y.AKEVGKKLVNS.D.FK.......NNR.....VSDP-TKVSD......KQVKQIKKYCKEYFDKAVVKQRA--ye.....
E6R923_CRYGW/634-723               ..............eLAEQKERRLRK..LIGAVVVKSMNKYKDM.......IEHDT...FKK.Y.ARECTDTLVKK.E.KK.......SPS....yQGAKYPSLSD......DKKAKIKSFTKDYTHKILKHLKEK-g......
H8X476_9ASCO/667-755               ...........vket---SLEAQWKH..IMAKHVPNLLKSYVEE.......IGKDN...VKG.C.AKEIVNNLASR.E.AH.......KGV.....PPSSSKELDK......HKLKKLKEYSDTYMDKFLSKYRSKH.......
D4D4R9_TRIVH/692-779               ..............lSEEKQKKIYEN..TLFPHVKYVVDKFKNK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VTDP-TKVSE......KQIKQVKKFCKEYFEKAVVKHQA--ye.....
E7R3E0_PICAD/604-692               ............rhi--SATEKQWTK..LFASAVPNMLKKYENE.......IGRDS...LKA.C.ARDIVHTLAQK.E.LK.......RRS.....DSKPPSELSH......EKKAKIKHFVKEYMAKFLVKLEEKK.......
E7QGC2_YEASZ/623-682               ..............sQSQRLEHNWNK..FFASFVPNLIKKNPQSk.....qFDHEN...IKQ.C.AKDIVKILTTK.E.LK.......K--.....----------......-------------------------xffksa.
I1C6I1_RHIO9/580-669               ...........dgal----NEAQLKK..GIGKIVTKYLSSKQKG.......LWKDDkhlFKE.L.ARKITHHIVDR.E.IQ.......SSR.....---KIQTMNS......YVRTKVEKFIDAHGVDLVNKI----vrkrkh.
Q0V466_PHANO/696-784               ..............lPQEKQEKIYEA..TLSHHVMNVAAHYRKK.......LEKDD...IKR.L.SKEVAKKLVRG.D.YK.......SGR.....VKDPTAKLSS......RHEKTVKNYVKEFMDKAVKKKEER-d......
G7YHS2_CLOSI/649-736               ...........psek----------S..TVGKFILRLLRPYRLPncmtgriESNED...LVH.V.TRKMTHAFVSK.E.LL.......RCR.....YTMP-PTLTE......TLQDRIRTSLTRYMTSRGAVYRRG-k......
G5ANQ9_HETGA/421-515               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
H0EJU8_GLAL7/591-677               ..............yPEEKQMKLYEN..TLLPHIKYVMAKFAKY.......LPKED...LKK.F.GKEVGKLLVKS.D.FK.......HKR.....VEDP-TKITE......KQEKKVKSFVRDYFEKVLKK-----rtai...
SET2_CHAGB/603-683                 ...plekqmkiyent-----------..-------HVVDRFHGK.......LPKEE...LKK.F.AREVNKKLVSS.D.YK.......NNR.....VEDP-TSIPP......KQAKKVRKYAHDFFDRAVAKYTEH-e......
SET2_YARLI/605-688                 ..............kPVNAQAHRLTK..LLAKVVPNQVSKYD--.......VDRER...AKK.C.SKDIVQILVDK.E.LK.......RPE.....---PMTEISD......EKAKKIKEFVKGYMGKVVKRLEEKE.......
C0RXX6_PARBP/697-784               ..............ySEEKQKRLYEN..TIFPHVKYVMDKFKHK.......LPKEE...LKR.Y.AKEVGKKLVNS.D.FK.......NHR.....VDDP-TKVSD......KQIKQIKRYCKEYFDKAVAKH----laye...
C1G685_PARBD/697-770               ..............ySEEKQKRLYEN..TIFPHVKYVMDKFKHK.......LPKEE...LKR.Y.AKEVGKKLVNS.D.FK.......NHR.....VDDP-TKVSD......KQIKQIK------------------rdat...
C8ZAZ6_YEAS8/623-713               ..............sQSQRLEHNWNK..FFASFVPNLIKKNPQSk.....qFDHEN...IKQ.C.AKDIVKILTTK.E.LK.......KDS.....SRAPPDDLTK......EKRHKVKEFINSYMDKIILKKKQKK.......
A3LU80_PICST/619-707               ...........sksi---SVEDKWRH..VLAKHVPNLIKKHEKE.......VGREN...IKG.C.ARDLVKILVAK.E.LK.......KDA.....EISPPKELDS......NKLKKIKEYSKVFMDKFLIKYRAKH.......
A8NJ83_COPC7/650-739               .............ek-EALKEKRLMK..LIGAVVVKSMSKYARG.......LQKDY...FKK.Y.AKELTQVITEK.E.KK.......SSS....yKEGRLESLSE......EKVAKIKKFSKDYIAKVLRKLEK--ag.....
B4IGT0_DROSE/145-240               ..............aSAREAHEKFRF..EISGHVANFLRPYRKEscqlgriTTDED...YKF.L.VNRLSYHITTK.E.MR.......YCE.....VSGNPLSCTE......SVKHKSYDFVNQYMRQKGLVYRRP-a......
Q6PCY9_MOUSE/638-732               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
Q8K0F3_MOUSE/318-412               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
G2X7E5_VERDV/649-737               ..............lPIEKQMKIYEN..TLFPHVKYVLDKYRHK.......LPKEE...LKR.L.GKEVNKTLVSS.D.YR.......KNR.....VEDPTVAINH......KKVKTIKQYVKDFLDRALIKFKER-q......
B3LPV5_YEAS1/623-713               ..............sQSQRLEHNWNK..FFASFVPNLIKKNPQSk.....qFDHEN...IKQ.C.AKDIVKILTTK.E.LK.......KDS.....SRAPPDDLTK......EKRHKVKEFINSYMDKIILKKKQKK.......
SET2_GIBZE/785-873                 ..............lPVDKRMKIYEN..TLFPHIKHVLDKFHHK.......LPKEE...LKR.F.GKDIAKKLVAS.D.FK.......NNR.....VEDPGAPLSD......KQVKKIKQYVKDFLDRAVKKYGEH-k......
F2RN17_TRIT1/692-779               ..............lSEEKQKKIYEN..TLFPHVKYVVDKFKNK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VTDP-TKVSE......KQIKQVKKFCKEYFEKAVVKHQA--ye.....
Q4RI17_TETNG/1492-1587             .......lgvlnldf--------FHSyhRMSQFIVQCLNPYRKPdcksgriSNTED...FKH.L.ARKLTHGVMNK.E.LK.......ACT.....-NPEDLECNE......KCEAQGQGVHQEIHAAVWFCVQAQ-g......
D8TC03_SELML/1202-1287             ..........tpdqi---------KK..ALSEYVVHLLTPLYKTr.....kIQKDA...FKA.I.AKKTTMKVMER.D.GI.......RDT.....DVNISDYLNG......KRKNKIRELVDKFVEKHLAETKQ--sa.....
F2SMP3_TRIRC/691-778               ..............lSEEKQKKIYEN..TLFPHVKYVVDKFKNK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VTDP-TKVSE......KQIKQVKKFCKEYFEKAVAKHQA--ye.....
G7MIS1_MACMU/2244-2338             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
H2UDT3_TAKRU/2288-2382             ..............eLAKKSKETFRK..EMSQFIVQCLNPYRKPdcklgriSNTED...FKH.L.ARKLTHGVMNK.E.LK.......ACT.....-NPEDLECNE......NVKHKAKEYIKKYMQRFGSVYRPKE.......
G2QBP9_THIHA/650-737               ..............lPIEKQMKIYEN..TLFPHVKHVVDKFHGK.......LPKEE...LKK.F.AREVNKKLVAS.D.YK.......NNR.....VEDP-TSVTP......KVAKKVRKYTYDFFERAAVKYAE--ye.....
D4AA96_RAT/2436-2530               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
G4MUF3_MAGO7/654-741               ..............wPADKQRRLYEN..TIFPHIKYVADKYYKR.......LPKED...LKK.F.VKDVNKTLAAS.D.YK.......HGR.....VNDP-SKVEE......KQQSKIRKYTRDFLDKAVKKHE---lrq....
H2QMH8_PANTR/2436-2530             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
G3P1H7_GASAC/637-731               ..............eLAKKSKETFRK..EMSQFIVQCLNPFRKPdcklgriSNTED...FKH.L.ARKLTHGVMNK.E.LK.......ACN.....-NPEDLECNE......NVKHKTKEYIKKYMQRFGTVYRPKE.......
C5K0U3_AJEDS/559-646               ..............ySEEKQKKLYEN..TIFPHVKYVVDKFKHK.......LPKED...LKR.Y.AKEVGKKLVNS.D.FK.......NNR.....VSDP-TKVSD......KQVRQIKKYCKEYFDKAVVKQRA--ye.....
G5CAT1_HETGA/325-418               .............dl-AKKSKEVFRK..EMSQFIVQCLNPYRKPdyk.vgrITTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKVYINKYMQKFGAVCKPK-e......
H9G639_ANOCA/2481-2575             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriNTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-TPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
G8BJV0_CANPC/670-758               ............gke--VSLESQWKH..VMAKHVPNLLKSYVDE.......IGKDN...VKG.C.AKEIVNNLAAR.E.AN.......KGA.....PPSSSKELDK......HKLKKLKEYSDTYMEKFLTKYRSKH.......
G1MV76_MELGA/2417-2511             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAIYKPK-e......
G8JX28_ERECY/591-679               ..............hSVSRSEHKWNK..FFASLVPNLIKSYESG.......LDRGR...IKD.C.ARDIVKILSNK.E.LK.......KDP.....NKVPPSEVTK......EKKKKVKEFCKIYMDKLVLKIHQK-p......
H0YPH4_TAEGU/2461-2524             qksgnegekylgnrs-----------..----------------.......-----...---.-.--TLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGILYKPK-e......
B6K1E8_SCHJY/654-745               ..............sSNDPKALKFKA..VLARFFANKTARYQDS.......LGKPE...FKS.R.VKKMTEIVLTK.H.LKl....vaSRQ.....EPELPQELSQ......SQQAKLKAWSLQYMEKVYLRLKD--hn.....
E0VVJ9_PEDHC/1348-1442             .............at-DKKIKENFKN..NMAGAIVSHLNPYRKQdckigriTCNED...FKH.L.ARKLTHFVMLK.E.LK.......HCK.....-GVDDLECND......SVKAKAKDFIKKYMAKFGAVYQRP-k......
A1CZG9_NEOFI/695-782               ..............ySEEKQKKLYEN..TLFPHIKYVVDKFKHK.......LPKED...LKR.Y.AKDVAKKLVNS.D.FK.......NNR.....VEDP-TKISE......KQQKKVKAFCKEFFDKAVAKHRA--ye.....
F9G813_FUSOF/644-732               ..............lPVEKQMKIYEN..TVFPHIKHVLDKFHHK.......LPKEE...LKR.F.GKEIAKKLVSS.D.YK.......NNR.....VGDPNAPLSE......KQARKMKQYVKDFLDRAVKKFGDQ-q......
G3UV50_MELGA/626-720               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAIYKPK-e......
A5DYF1_LODEL/674-762               ..............sKENSIESQWKR..VLAKHIPNLIKKHQAE.......IGKDN...VKG.C.AKEIVNNLARR.E.AQ.......KEN.....AKLPPEELEK......HKIKKIKAFTDSFMDKFLIKYRRKH.......
E1FRX0_LOALO/1329-1415             ..........ridtr------ATFKV..EIVKYVGGMLEPIRKLk.....fASADD...YKY.V.LRKLTHTILEK.E.LK.......RVG.....--ETELKVTE......SVRDKARKFVAEYLARLG-------dgqysrk
B4J2R7_DROGR/1960-2054             .............tt-VRDSNEKFHF..EISGHVAEFLRPFRQDtchlgriTSDED...YKF.L.IKRLSLHITTK.E.MR.......YCE.....VTGNPLACTE......SVKHKSYEFIKQYMRKKGPVYKK--p......
G1XCW9_ARTOA/707-791               ...lhherrvkfayy-----------..---TIVKETTAIFLPK.......MGKAE...IKK.R.NEEITRLCARK.D.MK.......KTG.....LKTP-IELSS......EKHRQIRKFTQDYMRSLWKKMKA--hy.....
G3UYE0_MOUSE/661-755               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
B0D7G3_LACBS/676-762               ..............eKEANKEKRLLK..LVGAVVVKCMSKYAKS.......LNHDL...FKK.H.AKEV---IAEK.E.KK.......SSS....yREGNLDALTE......EKISKIKKFAKEYIAKILRKLEK--sg.....
A0NGT7_ANOGA/2299-2394             ..............eEAKKIKEKFRV..DIAGVIVQHLSSYRKDscplgriTNTDD...FKH.L.ARKLTHFVMLK.E.LK.......HCD.....NTVHELEVTD......SVKTKAREFIKKYMAKHGPVYVR--ge.....
B8NSI5_ASPFN/689-776               ..............ySEDKQKKVYEN..TLFPHIKYVVDKFKHK.......LPKED...LKR.Y.AKDVAKKLVNS.D.FK.......NNR.....VEDP-TKISE......KQQKKVKKYCKEFFDKAVLKHRA--ye.....
SET2_DEBHA/622-710                 ...........appv---PIDGQWTK..TFAKHVPNFLKKYEAE.......IGRDN...IKG.C.AKELVKTLVAK.E.MK.......KNP.....DTKPPKELDN......AKLKKIKEYSKMFMDKFLIKYRSKH.......
C5FVL3_ARTOC/688-775               ..............fSEEKQKKVYEN..TLFPHVKYVVDKFKNK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VSDP-TKVSD......KQVKQVKKFCKEYFEKAVVKHQ---vye....
C5DKG6_LACTC/596-684               ............skg--DYMLHKWNR..FFAGFVPNLVRHYEKD.......LGKDH...IKE.C.ARDIVKTLSSK.E.LK.......KDP.....KKSPPPEPSK......EKKAKVREFTKVYMEKFSQKYAQR-k......
H9WGG1_PINTA/1-86                  .............ds---RSMKLFRS..ALAEFVKEALKPSWREg.....hMSKEA...FKT.I.VKKAVDKVAG-.A.MQ.......NHQi..pkSRGRIDQYVA......SSERKLTKLVQGYVDKYVR------v......
B6QGD6_PENMQ/697-784               ..............yPEEKQKKIYEN..TIHPYVKYVVDKFRKK.......LPKED...LKR.Y.AKEVATKLVDS.D.FK.......HSR.....VEDI-LQISE......KQQQKIKKYCKEYFEKAVAKHKAH-e......
G4UQ54_NEUT9/659-746               ..............lPVEKQMKIYEN..TLFPHVKYVMDKFHRR.......LPKED...LKR.F.GREINKKLVAS.D.YK.......NHR.....VDDP-TTISS......NQARKIKKFVKDFFDRAVVKHREN-e......
F2TIW0_AJEDA/700-787               ..............ySEEKQKKLYEN..TIFPHVKYVVDKFKHK.......LPKED...LKR.Y.AKEVGKKLVNS.D.FK.......NNR.....VSDP-TKVSD......KQVRQIKKYCKEYFDKAVVKQRA--ye.....
C5GXS6_AJEDR/559-646               ..............ySEEKQKKLYEN..TIFPHVKYVVDKFKHK.......LPKED...LKR.Y.AKEVGKKLVNS.D.FK.......NNR.....VSDP-TKVSD......KQVRQIKKYCKEYFDKAVVKQRA--ye.....
C4QY01_PICPG/630-719               ..........kskrp---TREQEWNK..LFATVVPNMIKKHESQ.......IGRDN...LKH.C.AKDIVHQLSSK.E.IK.......KDT.....SKKPPKELSS......EKKAKVKAFVGPYMEKYLDKWKAKH.......
G1R333_NOMLE/2436-2530             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
E2LHR9_MONPE/52-95                 ............ter-EANKEKKLQK..LVGAIVVKSMSKYAKS.......LEHDM...FKK.Y.AKEV-------.-.--.......---.....----------......-------------------------hf.....
E3WZW3_ANODA/2527-2622             ..............eEARKIKEKFRV..EIAGVIVQHLSGYRKEncpigriTNTED...FKH.L.ARKLTHFVMLK.E.LK.......HCD.....NTVHVLEVTE......SVKTKAREFIKKYMAKYGAVYVR--ge.....
A1C9T9_ASPCL/696-783               ..............ySEEKQKKLYEN..TLFPHIKYVVDKFKHK.......LPKED...LKR.Y.AKDVAKKLVNS.D.FK.......NNR.....VEDP-TKISE......KQQKKVKAFCKEFFDKAVAKHRAH-e......
G1M2A2_AILME/2441-2535             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
I1RNH8_GIBZE/670-750               ...........tnmh-----------..QLFPHIKHVLDKFHHK.......LPKEE...LKR.F.GKDIAKKLVAS.D.FK.......NNR.....VEDPGAPLSD......KQVKKIKQYVKDFLDRAVKKYGEH-k......
F6UQE2_MONDO/1983-2077             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGTVYKPKE.......
A6ZQG4_YEAS7/623-713               ..............sQSQRLEHNWNK..FFASFVPNLIKKNPQSk.....qFDHEN...IKQ.C.AKDIVKILTTK.E.LK.......KDS.....SRAPPDDLTK......EKRHKVKEFINSYMDKIILKKKQKK.......
B4H7D3_DROPE/3-65                  .............ri-----------..----------------.......TSDAA...YKF.L.IKRLTEHIITK.E.MR.......YCE.....MSGHPLICND......SVKHKSHEFINQYMLKKGRVYVM--pa.....
B7QG36_IXOSC/1492-1586             .............ev-AKKIKELFRS..KISSHIVHCLNPFRKPdcklgriQSTED...FKH.L.ARKLTHFVMAK.E.LK.......HCK.....-NVEDLECND......NVKHKAKEFVHKYMAKYGPLF----ykkd...
A9NXI7_PICSI/401-488               .............nk-DSRSMKLFRQ..ALAEFVKEALKPSWREg.....hMSKEA...FKT.I.VKKAVDKVAG-.A.MQ.......NHQi..pkSRGRIDQYVA......SSERKLTKLVQGYVDKYVR------v......
C7YYN9_NECH7/656-744               ..............lPIEKQMKIYEN..TLFPHIKHVLDKFHHK.......LPKEE...LKR.L.GKDIAKKLVAS.D.YK.......NNR.....VGDPSSPLSD......KQAKKMRKFVNDFLDRAVEKYGEH-q......
F1KR78_ASCSU/855-943               .........sdhsdp-----RAVFKA..LIAKHVAGILEPIRKTk.....fSSSDD...YKY.V.LRKLTHTVLEK.E.TK.......RIG.....--GGELKVTE......SVKEKARRYVNDYIARLGE------gqysrk.
G0S676_CHATD/653-741               ..............lPIEKQMKIYEN..TLFPHVKYVMDKFHGK.......LPRED...LKK.F.ARDVNKKLVAS.D.YK.......HNR.....VQDPTVPLSS......KQAKKVRKYVYDFFDRALQKYLE--yq.....
SET2_YEAST/623-713                 ..............sQSQRLEHNWNK..FFASFVPNLIKKNPQSk.....qFDHEN...IKQ.C.AKDIVKILTTK.E.LK.......KDS.....SRAPPDDLTK......GKRHKVKEFINSYMDKIILKKKQKK.......
#=GR SET2_YEAST/623-713      SS    ..............-HHHHHHHHHHH..HHHHHHHHHHHTSTTTT.....T--HHH...HHH.H.HHHHHHHHHHH.H.HH.......H-T.....T----SS--H......HHHHHHHHHHHHHHHHHHHHHHHHT.......
B4R4C9_DROSI/2148-2243             ..............aSAREAHEKFRF..EISGHVANFLRPYRKEscllgriTTDED...YKF.L.VNRLSYHITTK.E.MR.......YCE.....VSGNPLSCTE......SVKHKSYDFVNQYMRQKGLVYRRP-a......
E5A0B0_LEPMJ/724-812               ..............lPQEKQEKIYEA..TLSTHVMSVTSHYRKK.......LEKDE...VKR.L.SKEVAKKLVRG.D.YK.......SGR.....VKDPTQKISS......SHEKTIKKYVKEFMDKAVRKKEER-e......
SET2_COCIM/690-777                 ..............ySEEKQKKLYEN..TLFPHVKYIVDKFKHK.......LPKDD...LKR.Y.AKEVAKKLVNS.D.FK.......NNR.....VEDP-TKISD......KQVKQVKKYCKEYFDKAVAKHRA--ye.....
G3AM54_SPAPN/605-693               ...........hddv---SVEAKWKH..VLAKHVPNLIKKYEKE.......IGRDN...LKG.C.ARDLVNSLASK.E.VK.......IDP.....KSSPPKELDH......HKLKKIKEFSKTFMEKFLVKYRQKH.......
SET2_ASPOR/707-794                 ..............ySEDKQKKVYEN..TLFPHIKYVVDKFKHK.......LPKED...LKR.Y.AKDVAKKLVNS.D.FK.......NNR.....VEDP-TKISE......KQQKKVKKYCKEFFDKAVLKHRA--ye.....
Q071D9_DANRE/270-364               ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdcklgriSNTED...FKH.L.ARKLTHGVMNK.E.LK.......SCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGSVYRPKE.......
E6ZVI7_SPORE/848-941               ............dlv--ASNERRLCK..LVGELVVRQMSKHKDE.......LERES...FKR.H.AKELTNAIVSK.E.MR.......NPKswppaRGAALTELST......DKKAKIKAFAKEYIDKLMARKGK--ak.....
H9IAB6_ATTCE/1739-1833             ..............mSERKIKDTFRI..NMANVMVHFLNPYRKNdckqgriTNTED...FKH.L.ARKLTHFVLAK.E.LK.......HCK.....-SVDELQCNE......NVKHKARDFVRKYMSKFGAVYQK--gt.....
C3YEA6_BRAFL/254-347               .............et-ARKCKDVFRK..KMATFVVSILNPYRKPdckhgriTSTED...FKH.L.ARKLTHGIMNK.E.LK.......HCR.....-HVEDLEVNE......NVKSKAREYVRKYMSKFD-------glyqss.
E9Q5F9_MOUSE/2438-2532             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
F4P7F7_BATDJ/1263-1351             ..........ssess---SKKVLIRK..ELHSIAIDQLSKFKHT.......ISIEK...FKT.M.AKSLVKAVTDE.V.GK.......SLI.....MELTDDKLVD......TSRTAAKKWVRMYLARHGCVH----sda....
E3KF80_PUCGT/725-811               .........nnpakd------KKMLR..LFSNVVVHTMSRYKDS.......LDHEQ...FKR.R.AKELTNILCEK.E.RK.......STH....yQSEMYEEMSA......AKEMKIKAFTKDWMVKLLTR-----kgi....
F2UKY3_SALS5/828-922               ...........dpas----ARAKFKK..DVSATVIKFLKRFRDEkvkfgriTNSDD...FKH.L.ARKLTHTMVEK.I.AQ.......RRG.....GELAGAVVDK......AMRTKIYDFVNASMKKCGPEYQR--sv.....
H2YKZ5_CIOSA/84-178                ..............eEAKKAREIFRS..KMSQHVVHCLNSYRKSdcqvgriTSTDD...FKK.L.ARKLTYNILMK.E.IK.......QVI.....VWDD-LEYNA......NVKHKAKEYVKKYMAKMGPIYKAK-d......
A6SPE7_BOTFB/680-767               ..............lPIEKQMKLYEN..TLFPHIKHVMQKYSGK.......LPKDD...LKK.F.AKECGKKLVAS.D.FK.......NNR.....IEDP-TKISD......RNQRKVKQYVFEYFKKAVEKKREM-d......
G0RRY8_HYPJQ/667-755               ..............lPVEKQMKIYEH..TVYPPVKHVLDKFRHK.......LPKEE...LKR.L.GKDVAKKLVAS.D.YK.......NNR.....VNDPAAPLTE......KQERNIKKYVKDFLDRAVAKYEAH-h......
I1CM29_RHIO9/751-835               ..........lsgte--------LKK..AIGKIVTKYLSSKSKDl....wnNDKYL...FKE.I.ARKITHHIVDR.E.TQ.......SSR.....---KIQSINS......SVRSKIEKFIDSHATELVSKI----ihkr...
I1CSD0_RHIO9/803-882               ..........edegl----NEIELKN..EIGKVVTKYLSLTNQQcl...wkGDKHL...FKD.M.ARKITHYIVDK.E.MK.......SGR.....---KIKALDS......NLRVKIEKFIDTF------------kq.....
G3WAZ4_SARHA/2469-2563             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGTVYKPKE.......
G4T5A8_PIRID/651-739               .............ei--SNKEKQLLK..LVGAAVVGYLSQWKSQ......fASPDD...FKR.H.AKEITEKIAEL.E.KKg.....rTYQ.....SNARLESLSE......EKRAKIKHYVKSYVGKLG-------lqssl..
G3BBE8_CANTC/616-703               .............tt--SSVEKRWSS..LFAKYVPNLIKKHTEE.......IGKDN...VKQ.C.AREMVKVLVMK.E.MN.......KDA.....TREPPADFEK......SKLKQVKEFTGSYMDKFMIKYRQKH.......
B2W0G7_PYRTR/696-784               ............lti--EKQEKVYEA..TIAPYIMSTANLYSKK.......LEKEE...FKS.L.CKEVAKKVVRG.D.YK.......NGP.....VKDPTAKIPL......NHQKRIKNCVHEYMNKAVKTAEER-r......
C1716_DROME/2215-2310              ..............tSAREAHEKFRF..EISGHVANFLRPYRKEsctlgriTSDED...YKF.L.VNRLSYHITTK.E.MR.......YCE.....VSGNPLSCTE......SVKHKSYDFINQYMRQKGPVYKKP-a......
B5VL18_YEAS6/623-713               ..............sQSQRLEHNWNK..FFASFVPNLIKKNPQSk.....qFDHEN...IKQ.C.AKDIVKILTTK.E.LK.......KDS.....SRAPPDDLTK......EKRHKVKEFINSYMDKIILKKKQKK.......
C9SV17_VERA1/651-739               ..............lPIEKQMKIYEN..TLFPHVKYVLDKYRHK.......LPKEE...LKR.L.GKEVNKTLVSS.D.YR.......KNR.....VEDPTVAINH......KKVKTIKQYVKDFLDRALIKFKER-q......
F1SNU6_PIG/640-734                 ..............eLAKKSKEIFRK..EMSQFIVQCLNPYRKPdckvgriTTTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLECNE......NVKHKTKEYIKKYMQKFGAVYKPKE.......
D8QG04_SCHCM/613-703               ...........eeke--AGKEKRLLK..LVGEVVVKSMSKYAKG.......LPRDV...FKK.Q.AKELTHIIAEK.E.KK.......SSS....fKEGKLDALSE......EKVYKMKKFSRDYIAKVMRKYQEKE.......
F7D163_XENTR/2440-2534             ..............eLAKKSKEVFRK..EMSQFIVQCLNPYRKPdckmgriNNTED...FKH.L.ARKLTHGVMNK.E.LK.......YCK.....-NPEDLDCNE......NVKHKTKEYIKKYMQKFGTVYKPKE.......
SET2_CRYNB/635-725                 ..............eLAEQKERRLRK..LIGAVVVKSMNKYKDM.......MEHDT...FKK.Y.ARECTDTLVKK.E.KK.......RNPs...yQDVKHPSLSD......DKKAKIKSFTKDYTHKILKHLKEK-g......
G0W5J9_NAUDC/684-774               .............si-SESNEHKWDN..FFASFVPNLVRKNTGDv.....eLSRDH...IKE.C.SRDIVKTLTSK.E.LK.......RDD.....PKPPPEEATK......EKKYKVNKFVKIYMEKFITKYKEKH.......
H3HSC8_STRPU/2925-3019             .............ea-AKRLKEAFRS..RMSHHVVGYLNAYRKPdcklgriTNTED...FKH.L.ARKLTHGIMAK.E.LK.......HCR.....-NIEDLEVNE......NVKHKAKEYIRKYMGRYGKLYKK--dp.....
H2AWM4_KAZAF/597-687               ...........rhth---RYEHHWNK..FFASFVPNLVRKYESDv.....hLTHDH...MKE.C.SRDIVKILTSK.E.LK.......KDP.....KNMPPEKLNK......DKHAKVKSFVKSYMDKFIAKYKQKK.......
E1JJN9_DROME/2215-2310             ..............tSAREAHEKFRF..EISGHVANFLRPYRKEsctlgriTSDED...YKF.L.VNRLSYHITTK.E.MR.......YCE.....VSGNPLSCTE......SVKHKSYDFINQYMRQKGPVYKKP-a......
H1V2C6_COLHI/659-747               ..............lSTDKQMKIYEN..TLFPHVKYVIDKYRHK.......LPKDD...LKR.L.GKDVCKKLVSS.D.YK.......GKR.....VQDPTTPLDQ......KQARKVKTYVKDFLDKAIVKFKQ--fe.....
#=GC SS_cons                       ..............HHHHHHHHHHHH..HHHHHHHHHHCTTTTTT.SSSBT--HHH...HHH.H.HHHHHHHHHHH.H.HH.......HHT.....T-GGGSS--H......HHHHHHHHHHHHHHCCCHCCHHHHC.......
#=GC seq_cons                      ..............t.tc+pcchacp..phutalsphlsta++p.......hscE-...hK+.h.A+cls+tlssK.E.hK.......psc......ss.shcls-......phc+KlKcalKcYhpKhssha+t.........
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