GenomeNet

Database: Pfam
Entry: SdrG_C_C
LinkDB: SdrG_C_C
Original site: SdrG_C_C 
#=GF ID   SdrG_C_C
#=GF AC   PF10425.7
#=GF DE   C-terminus of bacterial fibrinogen-binding adhesin
#=GF AU   Finn RD, Coggill PC
#=GF SE   Gene3D, pdb_1r17
#=GF GA   21.40 21.40;
#=GF TC   26.50 29.40;
#=GF NC   20.90 19.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   SdrG_C_terminal_protein_domain
#=GF RN   [1]
#=GF RM   14567919
#=GF RT   A "dock, lock, and latch" structural model for a staphylococcal
#=GF RT   adhesin binding to fibrinogen. 
#=GF RA   Ponnuraj K, Bowden MG, Davis S, Gurusiddappa S, Moore D, Choe D,
#=GF RA   Xu Y, Hook M, Narayana SV; 
#=GF RL   Cell. 2003;115:217-228.
#=GF DR   INTERPRO; IPR011266;
#=GF CC   This is the C-terminal half of a bacterial fibrinogen-binding
#=GF CC   adhesin SdrG. SdrG is a Gram-positive cell-wall-anchored adhesin
#=GF CC   that allows attachment of the bacterium to host tissues via
#=GF CC   specific binding to the beta-chain of human fibrinogen (Fg).
#=GF CC   SdrG binds to its ligand with a dynamic "dock, lock, and latch"
#=GF CC   mechanism which represents a general mode of ligand-binding for
#=GF CC   structurally related cell wall-anchored proteins in most
#=GF CC   Gram-positive bacteria. The C-terminal part of SdrG(276-596) is
#=GF CC   integral to the folding of the immunoglobulin-like whole to
#=GF CC   create the docking grooves necessary for Fg binding. The domain
#=GF CC   is associated with families of Cna_B, Pfam:PF05738 [1].
#=GF SQ   41
#=GS C8PC72_9LACO/125-277    AC C8PC72.1
#=GS C2BGP3_9FIRM/4686-4842  AC C2BGP3.1
#=GS SDRC_STAA8/336-485      AC Q2G0L5.1
#=GS H3NIB7_9LACT/317-484    AC H3NIB7.1
#=GS K1LBH0_9LACT/268-430    AC K1LBH0.1
#=GS C0MFY9_STRS7/943-1091   AC C0MFY9.1
#=GS E6MB43_STALU/437-585    AC E6MB43.1
#=GS A5VHN3_LACRD/220-387    AC A5VHN3.1
#=GS B9DJ62_STACT/567-737    AC B9DJ62.1
#=GS G5KI16_9STRE/349-505    AC G5KI16.1
#=GS C7XUD1_9LACO/271-411    AC C7XUD1.1
#=GS H3NL27_9FIRM/739-898    AC H3NL27.1
#=GS V4QRG6_STRIN/350-509    AC V4QRG6.1
#=GS Q2G1T5_STAA8/291-439    AC Q2G1T5.1
#=GS CLFB_STAA8/367-524      AC Q2FUY2.1
#=GS F9MW46_9FIRM/277-448    AC F9MW46.1
#=GS F0H0K9_9FIRM/4138-4300  AC F0H0K9.1
#=GS G4D2J9_9FIRM/1034-1187  AC G4D2J9.1
#=GS B0S003_FINM2/4232-4393  AC B0S003.1
#=GS H3NE91_9LACT/504-635    AC H3NE91.1
#=GS K0YDY7_9CORY/196-344    AC K0YDY7.1
#=GS E6M808_STALU/357-509    AC E6M808.1
#=GS CLFA_STAA8/373-525      AC Q2G015.1
#=GS CLFA_STAA8/373-525      DR PDB; 2VR3 A; 373-525;
#=GS CLFA_STAA8/373-525      DR PDB; 2VR3 B; 373-525;
#=GS C7HVI4_9FIRM/1143-1298  AC C7HVI4.1
#=GS E8SES1_STAPH/433-583    AC E8SES1.1
#=GS Q5HRI6_STAEQ/389-540    AC Q5HRI6.1
#=GS G5KHS3_9STRE/235-396    AC G5KHS3.1
#=GS E4L031_9FIRM/4013-4216  AC E4L031.1
#=GS E8SHD7_STAPH/324-467    AC E8SHD7.1
#=GS E8SH04_STAPH/324-481    AC E8SH04.1
#=GS G5K4P3_9STRE/124-268    AC G5K4P3.1
#=GS H3NL27_9FIRM/1569-1729  AC H3NL27.1
#=GS Q8DYL7_STRA5/475-627    AC Q8DYL7.1
#=GS E0NIX5_9FIRM/4508-4663  AC E0NIX5.1
#=GS K1M3I9_9LACT/291-412    AC K1M3I9.1
#=GS G5K926_9STRE/396-549    AC G5K926.1
#=GS SDRD_STAA8/397-559      AC Q2G0L4.1
#=GS H3NQ17_9FIRM/296-457    AC H3NQ17.1
#=GS FNBA_STAA8/341-496      AC P14738.1
#=GS FNBA_STAA8/341-496      DR PDB; 4B60 B; 341-496;
#=GS FNBA_STAA8/341-496      DR PDB; 4B60 A; 341-496;
#=GS FNBA_STAA8/341-496      DR PDB; 4B5Z A; 341-496;
#=GS C7REI7_ANAPD/4217-4382  AC C7REI7.1
#=GS F2I830_AERUA/337-501    AC F2I830.1
C8PC72_9LACO/125-277               ........gqd--NLNSNGTA....NLFDIDEST..GTYKETIYVNN...KQR.E.Q....N.N.TRI--LIENG................gNDSFTTFDG...QvVKSIE............VYKVKDPS..........KLSGSMDLD..--MDNLE.KVSP..........tQYDQ.............KLKADRSG-...IELDLKNQGT....KDVYVV..RYNGKYDSSKNAN.IKTT--.IVADPQNNP---.........------yevaehfas.......................................................
C2BGP3_9FIRM/4686-4842             .........ty--NYWHNLTG....KITEMDKTT..GEFTQYYYINR...MKD.KgW....K.N.WTFRYNPYSS.................-DKTNTKRL...S.YANVR............VMKLKDNSdan....iarSMPESFALD.iNNDSNLT.EIYNqrfdrmgatsfNFSG.............YKEGNQPNG...YMPNAGSDE-....GDSYIV..EVKGKIP------.------.------------.........------lseikefesvasii..................................................
SDRC_STAA8/336-485                 ..........g-NKKAQPLIS....STNYINNED..LSRNMTAYVNQ...PKN.T.Y....T.K.QTFVTNLTGY.................-----KFNP...N.AKNFK............IYEVTDQN..........QFVDSFTPD..--TSKLK.DVTD...........QFD-.............VIYSNDNKT...ATVDLMKGQTs..sNKQYII..QQVAYPDNSSTDN.GKIDYT.LDTDKTKYSWSN.........SYSNVN................................................................
H3NIB7_9LACT/317-484               ........lkg----FPSVGS....LVVSSDLNK..NTFRQIIYVNPlegNQQ.T.T....T.N.TTL--TFSNR.................GNQNSITNA...A.GANIK............IYKVPTASr........kYMPYSYAYN..--QKTFD.EGIEsg......evlDFSEkf........didRVQRTTESSldkFTINFGTVDP....RDSYVI..VVDGKFIN-----.------.------------.........------ldetndnpqylsqvfydfddikvnkdqn....................................
K1LBH0_9LACT/268-430               .......tgnn-----LNGMS....QITEFNPET..GEFTQVFYINP...DSK.T.I....T.T.SNRNWATGKVamfid......gltpdkTPSDVNYTK...E.NTKVS............IQKLPSGT..........KLPNAIIEN.pVKTDEQT.MVKT...........TFRDg..........giEITFAENGD...KNLRHDNI--....DSPYIV..TVKSIAAPSKTGNnVYSRAT.------------.........------fygdgtrfhvmd....................................................
C0MFY9_STRS7/943-1091              ......dsysp-----VNIGS....MLTKLDLKQ..ELFTNYVYINP...RHY.S.L....S.N.GRLVFSGQGA.................-----AIID...E.NTQVT............LYLANDAY..........DMPPSWGID..--DKRLI.EEKS...........----.............-IKINKSLG..rIDIDFQNRLY...sGQSFIL..KIVGRYDINSDAP.IKTSAT.LYQNYYNYYGYY.........------tekgrwipq.......................................................
E6MB43_STALU/437-585               ..........g-DNKNNPLNA....STLYRDPKT..NQQYRIIYINE...PGK.T.Y....K.N.VKYHSTTMNG.................-----KLID...G.TDAIK............VYKVNDPS..........AMVNSFAPD..LTSSKVT.DVTS...........--SK.............TITYDNNRS..tVNVSLGNLDG....KTRYIIaeKVEPTTDNGNL-S.STFSIT.NDDKNN------.........------ptiwaasttq......................................................
A5VHN3_LACRD/220-387               ..........a-NDMFLGISS....RMMHFDKDQ..QLFEDIIYVNP...AQK.D.L....N.H.AYIVFNTSDLv...............eELSNAVVKP...S.TMRVE............IYRNSRGL..........KLPQSYGVN..--LQRLR.DITN...........RFPVvegdh..lveapyTMSFADNK-...MRLNFGADQT....NDSYII..RVVGQYNDELDGT.VRLRAR.LFGMDQQNVYMS.........N-----staatat.........................................................
B9DJ62_STACT/567-737               .........ds--QLSSNIDS....FITHTDQAT..GDYQQVIYVNP...QGK.E.A....Y.N.TKV--NLYNYwpn..........qntpGDSSAQLNP...D.VTSYK............IYEVRNGQ..........EMYPSYYLD..ENNPNLV.DVTDwnn.....qdyNFNP.............TYSTDANGGe.vLTLDFQNLTS...nGSQYII..VLDSKSENGNRES.IKTRVE.MSSDVTPDGQGH........nYYTWDN................................................................
G5KI16_9STRE/349-505               .........vg--NQDLQINS....RIVQQDETT..QTVTYNTLVNP...NGN.N.L....T.T.SYHYY--SEItnvtn......tddgtgHIITSTVNL...R.DATVQ............IYRGTTT-..........TIGQSINPD..--LSTLT.DVTD...........VYS-.............-HTVDQYGN...IVIDWGNNAFsdtnNNVYMI..VVKASYNNTED--.IGLVS-.------------.........------sletivlnrykfaa..................................................
C7XUD1_9LACO/271-411               .......qnda----QYGFSA....RIYDIDFSN..GKYKVNAYFNA...QNK.P.L....D.N.QQI--EIWAR.................GDNNTDLNP...K.SCTFR............VYRVKDGK..........TLNASLIPD..--YSEYD.DITN...........QLKIstneadaetpgvlYYD-AATNT...VKINFGGKQD....SNAYIL..HFEGQS-------.------.------------.........------pvkngkvh........................................................
H3NL27_9FIRM/739-898               ......npsnp-----INIDT....SFYYTNDQN..GKYTQLVYVNP...LKN.N.I....NiS.TNLEITPYINhqgv.........dksiDNIVANIDP...I.NTTIK............IYKLKDVN.........aKFDQAVIFD..--ETKLI.DVTT...........QFNG.............KINIINGK-...ATISFSKPIN....SESYLV..KIDSNMKY-----.------.------------.........------ptgviqgtflaqtavlrssnayvski......................................
V4QRG6_STRIN/350-509               ........qhg----NYNVDS....RIIKANFTD..FSFKYVTQINP...LGK.L.I....S.T.SNFSPLVSVIq...............nADQDSHIDL...S.KVNYK............IYKLIGSD..........LLSESMNED.yLNTNKFE.DVTQ...........NFRS.............EFNSEANA-...RVIYWDKSYI....QEKFII..VVEGSAEKDSK-T.LSVSTT.IEPLNSY-----.........------yqegvkyaagvrlyg.................................................
Q2G1T5_STAA8/291-439               ..........r-DNWGVTANG....RIDTLNKVD..GKFSHFAYMKP...NNQ.S.L....S.S.VTVTGQVTKG.................----NKPGV...N.NPTVK............VYKHIGSD..........DLAESVYAK.lDDVSKFE.DVTD...........NMS-.............-LDFDTNGG...YSLNFNNLDQ....SKNYVI..KYEGYYDSNAS-N.LEFQTH.LFGYYNYYYTSN.........-LTWKN................................................................
CLFB_STAA8/367-524                 ..........d-KPNGANISS....QIIGVDTASgqNTYKQTVFVNP...KQR.V.L....G.N.TWV--YIKGYqd.............kiEESSGKVSA...T.DTKLR............IFEVNDTS..........KLSDSYYAD..PNDSNLK.EVTD...........QFKN.............RIYYEHPNV...ASIKFGDI--....TKTYVV..LVEGHYDNTGK--.-NLKTQ.VIQENVDPVTNRd......ysIFGWNN................................................................
F9MW46_9FIRM/277-448               ......elssd-----VNGKS....QFIAYNPKT..GEFTQVFYLNP...ESK.E.I....T.P.STT--DDQNGrqmgkvgfllssphdadKPRSVDYLA...N.NTKIE............VKKLPKGA..........KLPDAIIEN.pEGAQPAT.NVKG...........EFR-.............--NFKGEPM...FTMNFGNGNK...iDSPYVV..VVKGHANEIDGKY.TELYSN.G-----------.........------tlygdgeaslfldnsytvq.............................................
F0H0K9_9FIRM/4138-4300             ........aei---YGLNMTS....KIVSFDRES..GEFVQYFYINR...NMN.Q.S....SdP.VTFRYKPSED.................---VKNLRV...D.VINLKq..........nGYDNNNRQgetnkefvnrDMPESFGVN..ESSDNLN.WHSW...........--YG.............YYQPKADEN...VDITLGPYNQ....YDSLIL..KVTGQVDKKDIAS.YDTYAK.LFNKVYTYDYYG.........------nvtnv...........................................................
G4D2J9_9FIRM/1034-1187             .........ss--NDGLNMNA....SFDYTNDQN..GKYSQVIYVNQ...KGS.N.I....T.V.PTH-LEITPYvds..........nyknGYIKANISP...I.ATAIK............VYKVKSGQ..........SLSNAVIYE..--KDKLE.DVTD...........QFKD.............KIKIDYGK-...ATVQFDNIG-....TDKYVV..VVDSNM-------.------.------------.........------iypqgqiqgtylaqvaslvnnnpssrv.....................................
B0S003_FINM2/4232-4393             ........egg---NTPNMTS....KIVSFDRET..GEFVQYYYINR...DKT.L.T....K.S.AEFEYTPSEA.................---------...-.VTNLKfdyyalrqnsgnIYDYNKGQyvd...pivkDMPESFGVD..ENSYNLN.WYYT...........--DG.............YYNLGAGQT...QKISLGTLGK....DNSLIL..KVTGKVKAENIAS.YDTYAK.MYGYYTEKWTDY.........-YGYSH................................................................
H3NE91_9LACT/504-635               qlngsrafvkv----------....------NSD..GNYRHVTYFNP...QKN.S.L....N.N.VQIEGVALGA.................----GTLNS...E.NSTVK............LYKVKDNR..........RLADSISANnyNDTTIFE.DVTR...........NYPTlnqfe...dvsfsGGKLTGKST...GKANLGNI--....NETYVM..VVDSKAKDD----.------.------------.........------gtl.............................................................
K0YDY7_9CORY/196-344               .........vd---RSLSLKS....HLYNVDPEA..GTYTVNSVVNP...YGQ.K.I....T.N.AVLFGGPQPD.................-RETSAVFG...G.DVDVK............VYRIDDPK..........DVPDSVVTD..-DVSEFV.DVTD...........--QV.............KKNSSRGEG...YEIHFPET-I....DTPYLV..VYNGTFDPSSDVP.LNTRHT.FEGC--------.........------hefagfdfmywdn...................................................
E6M808_STALU/357-509               ........gef---RNLSIKG....TIDQIDKVN..NTYRQTVYVNP...SSD.T.V....V.D.PYLRGGSIPG.................TNSNVIIDE...Q.NTSIK............VYKVKEKA..........HLTDSYYVD..--PSNYE.DVTS...........--DV.............KITFPEKGI...YQINFNTEDDq..iNSPYVV..VINGHVDPNSNGN.LYLRST.LYGYDSNFTRVS.........-MAWDN................................................................
CLFA_STAA8/373-525                 .........gk--FYNLSIKG....TIDQIDKTN..NTYRQTIYVNP...SGD.N.V....I.A.PVLTGNLKPN.................TDSNALIDQ...Q.NTSIK............VYKVDNAA..........DLSESYFVN..--PENFE.DVTN...........--SV.............NITFPNPNQ...YKVEFNTPDDq..iTTPYIV..VVNGHIDPNSKGD.LALRST.LYGYNSNIIWRS.........-MSWDN................................................................
#=GR CLFA_STAA8/373-525      SS    .........EE--ETTEEEEE....EEEEEETTT..TEEEEEEEEST...T--.-.E....E.E.EEEEEEE-TT.................S---EE-ST...T.T-EEE............EEE-S-GG..........GS-SS----..--GGGSE.E-GG...........--GS.............EEEEEETTE...EEEE-----SE..E-S-EEE..EEEEEE-TT-SS-.-EEEEE.EEEE-TT--EEE.........-EEEEE................................................................
C7HVI4_9FIRM/1143-1298             .........vg--NTHLNMAS....KITSFDVKT..GKFEQYFYINK...LRK.T.S....G.P.LNFYYRPNQL.................------VTN...L.EIETQ............ALNNNSGQni......nlYMPESFGVN..DNSPGTT.KYHK...........AYWE.............SVAQGGSAN...YRLESSNVSQ....NDSYIV..KVTGYLKVGEETD.YESTVY.LEDAITRY----.........------yvqrvnsiyvfk....................................................
E8SES1_STAPH/433-583               .........vg----DSNLKS....MITMEDSKT..GEYEQYIYVNP...LKR.D.A....Y.G.TVV--RVQGFqn.............dpATSNGQVNP...D.TTQIK............ILKVSDGQ..........TLNSSFGVD..--DSQYE.DVTD...........KFK-.............TVYRDGENL...ADIFLGDLN-....GARYII..KVTSKEVSGSSED.LKLRSS.MYTKNTYGQYDR.........-LTWDN................................................................
Q5HRI6_STAEQ/389-540               ..........n-ENRTANLQS....MFTNIDTKN..HTVEQTIYINP...LRY.S.A....K.E.TNV--NISGN.................GDEGSTIID...D.STIIK............VYKVGDNQ..........NLPDSNRIY..-DYSEYE.DVTN...........--DD.............YAQLGNNND...VNINFGNI--....DSPYII..KVISKYDPNKDDY.TTIQQT.VTMQTTINEYTGe......frTASYDN................................................................
G5KHS3_9STRE/235-396               ........vyg----TSSIQT....VFNEVDTTN..NTVEQIIYINT...NNA.Y.S....G.A.TAYNNILSIYggll........qngtiVENGSETVN...N.TSTIE............IYEAGNGS..........TLPKSMKIT..-DYSNFK.KVDS...........DTIA.............SNSTYYSDR...VDIDFGDI--....NTAYVI..RVVSSYDANSTDN.LVQSAN.MYSRDASGT---.........------vfnyynteas......................................................
E4L031_9FIRM/4013-4216             ........dkv---SFMNLGS....KITKFNPET..GEFVHYYYINR...DKE.N.I....G.A.SKFIYHSDQN.................-----IKNF...K.ITGID............ITDNKNID.........dVMPESFGLD..EDNSNYK.AKEL...........--VS.............LQYLSKGKE...AVLNFKEGFK...eNESYII..KVTGNVSDTNKMA.YVGHGK.LDRTYQT-----.........------agyflyvtrkdqvygfanstnakadlsiqavnpenkirflkvdqdgkplkgasfslniqdkdgn
E8SHD7_STAPH/324-467               .....yydnsh------YVDG....RISQVNKKE..AKFQQIAYINP...NGY.L.N....G.R.GTIAVNGEVV.................--SGTTKDL...M.QPTVR............VYQYKGQG..........VPPESITID..--PNMWE.EISI...........----.............TMVRKYDGG...YSLNLDTS-K....NQKYAI..YYEGAYDAQAE-T.LLYRTY.I-----------.........------qslnsyypfsyqkmn.................................................
E8SH04_STAPH/324-481               .........ks--PSGITLNG....RLDELSKAD..QSFTHYAIFKP...KHN.N.L....T.N.VTLRGTVSNN.................----AQQNE...K.NGQVN............VYEYIGQG..........ELPQSAYAN.vKDTNQFR.DITN...........--SL.............RPTTVNSTG...YQITFDHIN-....KKPYVI..VYKGHYKNEAK-D.LEFTTN.ATDYHSSNLYSYnywpyygsfNLTWKN................................................................
G5K4P3_9STRE/124-268               .......dthn----PVNIGS....MITSLDEAT..GDFVNYIYVNP...LGK.R.L....E.Q.TQLTYTG---.................--SGSTIIN...Q.DTRVQ............VFEVSYPT.........vQMPPSWGVD..--DKSMR.EVFD...........---T.............NISKSDGR-...ILIDFYDDLL...yGKSYIV..KISGKSDLKNSDP.IHTEAV.LQQRYFNYYS--.........------ywmesg..........................................................
H3NL27_9FIRM/1569-1729             .......ydnv-----SGLGS....TITEYDGSK..SYYKHVVYLNP...YGS.R.M....Y.Y.GDR--TVLSYifd...........tngDKNSSAIVN...N.TTKMD............LYLVNNLS..........DFAESYSFD.tNGKYKLR.EGVD...........----.............YIRQNYNGT...VEINFINYKPi..dGYKIAL..VVDGKMDMDSDKP.LNPSVK.LYN---------.........------awieydvygnqveynhwh..............................................
Q8DYL7_STRA5/475-627               ..........h-TNVKTNVRS....RIMKLDDER..QTETYITQINP...EGK.E.M....Y.F.ASGLGNLYTIig.............sdGTSGSPVNL...L.NAEVK............ILKTNSK-..........NLTDSMDQN..YDSPEFE.DVTS...........QYS-.............--YTNDGSK...ITIDWKTNSIs..sTTSYVV..LVKIPKQSG----.-VLYST.VSDINQTYGSKY.........SYGHTN................................................................
E0NIX5_9FIRM/4508-4663             .........yd--NATVSLAS....KITQYNTKT..GEFVHYFYVNR...DRQyN.N....K.D.QYFTYTPNVA.................--------V...D.DLQLT............YYKLRYNSeyy....inqSMPESFAVN..ESDSNLV.RSGG...........--TS.............PEDVAANKK...VTYNIGNLGP....KGSMII..KVTGRMKATGTEK.QVLSYKgVSGLYSKYYYYY.........------dywgnyig........................................................
K1M3I9_9LACT/291-412               ..snvlyevid----------....--------S..RDYTNISYFNP...TFN.Q.L....Q.S.GTY-GLIYPF.................KTSDSAINPmefE.KAKVT............IYEVSEGN..........KLNESHYFV..PEEVNAV.DVTN...........--DV.............NLTFDQSSN..gWRFDLINP--....NKSYVA..VTKGKA-------.------.------------.........------rqllpge.........................................................
G5K926_9STRE/396-549               .........vq---GTSSIES....VINELDTTK..HTVEQIFYVNP...KQY.N.A....Y.S.TIF--SVFGYivdp........ntgaiRQQGSNIID...K.STVID............VYKAGTRS..........MLPDSMNIT..-DFSGLT.KVTP...........----.............TITYGSDT-...ANIYLNNI--....SDVYVI..KVVSSYDPNSKDD.IVQSGT.MSSYDSSLRYYS.........IVESD-n...............................................................
SDRD_STAA8/397-559                 .........vv--NEKNSIGSafteTVSHVGNKEnpGYYKQTIYVNP...SEN.S.L....T.N.AKL--KVQAYhs.............syPNNIGQINK...D.VTDIK............IYQVPKGY..........TLNKGYDVN..--TKELT.DVTN...........QYLQ.............KITYGDNNS...AVIDFGNA--....DSAYVV..MVNTKFQYTNSES.PTLVQM.ATLSSTGNKSVSt......gnALGFTN................................................................
H3NQ17_9FIRM/296-457               ..........t-DNNGTNIGS....AIASVNTND..NTFTQIIYVNR...YIG.S.TppylG.S.LKLNYNIYSD.................-----SAIT...N.VTSVE............AYKIKDAYfsy....istLMPTSFNPD.lSDTRYYEkDYVN...........----.............--VSGAGIS...KSITFGPNTGy..iNNPYII..KIMGTYNEKST--.YPIRST.SNIENTRYGYSY.........-LGN--asitttvn........................................................
FNBA_STAA8/341-496                 .........ig--NYYANLNG....SIETFNKAN..NRFSHVAFIKP...NNG.K.T....T.S.VTVTGTLMKG.................----SNQNG...N.QPKVR............IFEYLGNN.........eDIAKSVYAN.tTDTSKFK.EVTS...........NMSG.............NLNLQNNGS...YSLNIENL--....DKTYVV..HYDGEYLNGTD-E.VDFRTQ.MVGHPEQLYKYYyd....rgyTLTWDN................................................................
#=GR FNBA_STAA8/341-496      SS    .........EE---SSEEEEE....EEEEEETTT..TEEEEEEEEEE...-SS.-.E....E.E.EEEEEEEEES.................------TTS...-.--EEE............EEEE-S-G.........GGS-TT----.TT-TTTEE.E-GG...........GHGG.............GEEE-TTS-...EEEEEEEE--....SS-EEE..EEEEE--TT-S-C.EEEEEE.EEEEC----SS---....--EEEEEEE................................................................
C7REI7_ANAPD/4217-4382             ........aei---YGLNMTS....KIVSFDRES..GEFVQYFYINR...NMN.Q.S....K.DpVTFRYKPSEDv...............kNLRVDVINL...K.QNGYN............YYNYNTRKkgtiqdfvnqDMPESFGVD..ESSDNLN.WHSW...........--YG.............YYQPKADEN...VDITLGPYNQ....YDSLIL..KVTGQVDKKDIAS.YDTYAK.LFNKVYTY----.........------drygnvtnv.......................................................
F2I830_AERUA/337-501               ........rkg----RLNINS....QFTEWNKDT..GEFTQVFYVNP...KSE.T.I....R.S.G-LNGSFENSvgmvvhnggreannilgAPSDVYYDA...D.NTKVE............IKKIPRGT..........NLPDAVYED..----PVA.GVLD...........K-DS.............EINYNNGQ-...LYIDFKKRQI....DSPYVV..VVKSKAKSHNGVD.YNLYSS.GVLHGD------.........------dgipgdiyswve....................................................
#=GC SS_cons                       .........EE--ETTEEEEE....EEEEEETTT..TEEEEEEEECC...TSS.-.E....E.E.EEEEEEEECT.................S---EETTT...T.T-EEE............EEEESSGG.........GGS-TT----.TT-CCCCE.E-GG...........GHGC.............CEEEECTTE...EEEEEEEE-SE..ESS-EEE..EEEEEE-TT-SSC.EEEEEE.EEEECTT--CCE--....--EEEEEEE................................................................
#=GC seq_cons                      ..........s....thslsS....plsphspps..spapphhYlNP...ppp.s.h....s.s.sph.hsspsh...................pssplss...p.ssslc............lYclsssp..........phscShshs...tssphp.-Vos.............p..............thshsssss...hslsassht.....sssYll..hVsGphcsssp.s.hthpsp.h.t........................................................................................
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