GenomeNet

Database: Pfam
Entry: SdrG_C_C
LinkDB: SdrG_C_C
Original site: SdrG_C_C 
#=GF ID   SdrG_C_C
#=GF AC   PF10425.8
#=GF DE   C-terminus of bacterial fibrinogen-binding adhesin
#=GF AU   Finn RD, Coggill PC
#=GF SE   Gene3D, pdb_1r17
#=GF GA   21.40 21.40;
#=GF TC   21.40 26.70;
#=GF NC   20.90 19.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   SdrG_C_terminal_protein_domain
#=GF RN   [1]
#=GF RM   14567919
#=GF RT   A "dock, lock, and latch" structural model for a staphylococcal
#=GF RT   adhesin binding to fibrinogen. 
#=GF RA   Ponnuraj K, Bowden MG, Davis S, Gurusiddappa S, Moore D, Choe D,
#=GF RA   Xu Y, Hook M, Narayana SV; 
#=GF RL   Cell. 2003;115:217-228.
#=GF DR   INTERPRO; IPR011266;
#=GF CC   This is the C-terminal half of a bacterial fibrinogen-binding
#=GF CC   adhesin SdrG. SdrG is a Gram-positive cell-wall-anchored adhesin
#=GF CC   that allows attachment of the bacterium to host tissues via
#=GF CC   specific binding to the beta-chain of human fibrinogen (Fg).
#=GF CC   SdrG binds to its ligand with a dynamic "dock, lock, and latch"
#=GF CC   mechanism which represents a general mode of ligand-binding for
#=GF CC   structurally related cell wall-anchored proteins in most
#=GF CC   Gram-positive bacteria. The C-terminal part of SdrG(276-596) is
#=GF CC   integral to the folding of the immunoglobulin-like whole to
#=GF CC   create the docking grooves necessary for Fg binding. The domain
#=GF CC   is associated with families of Cna_B, Pfam:PF05738 [1].
#=GF SQ   55
#=GS C8PC72_9LACO/125-277        AC C8PC72.1
#=GS A0A0X8FKI8_9LACT/443-590    AC A0A0X8FKI8.1
#=GS C2BGP3_9FIRM/4686-4842      AC C2BGP3.1
#=GS SDRC_STAA8/336-485          AC Q2G0L5.1
#=GS A0A0J6WRI6_9FIRM/1-50       AC A0A0J6WRI6.1
#=GS A0A133QA33_STALU/357-509    AC A0A133QA33.1
#=GS A0A0A8HP03_STAHY/363-510    AC A0A0A8HP03.1
#=GS H3NIB7_9LACT/317-484        AC H3NIB7.1
#=GS K1LBH0_9LACT/268-430        AC K1LBH0.1
#=GS C0MFY9_STRS7/943-1091       AC C0MFY9.1
#=GS A5VHN3_LACRD/220-387        AC A5VHN3.1
#=GS B9DJ62_STACT/567-737        AC B9DJ62.1
#=GS G5KI16_9STRE/349-505        AC G5KI16.1
#=GS A0A0A8HPX7_STAHY/420-571    AC A0A0A8HPX7.1
#=GS C7XUD1_9LACO/271-411        AC C7XUD1.1
#=GS H3NL27_9FIRM/739-898        AC H3NL27.1
#=GS A0A0A8HQN5_STAHY/288-443    AC A0A0A8HQN5.1
#=GS V4QRG6_STRIN/350-509        AC V4QRG6.1
#=GS Q2G1T5_STAA8/291-439        AC Q2G1T5.1
#=GS A0A0A8HSB6_STAHY/274-424    AC A0A0A8HSB6.1
#=GS CLFB_STAA8/367-524          AC Q2FUY2.1
#=GS A0A0A8HPX0_STAHY/354-505    AC A0A0A8HPX0.1
#=GS F9MW46_9FIRM/277-448        AC F9MW46.1
#=GS A0A0D6XSV0_9STAP/352-507    AC A0A0D6XSV0.1
#=GS F0H0K9_9FIRM/4138-4300      AC F0H0K9.1
#=GS G4D2J9_9FIRM/1034-1187      AC G4D2J9.1
#=GS B0S003_FINM2/4232-4393      AC B0S003.1
#=GS A0A033U795_STAAU/464-618    AC A0A033U795.1
#=GS H3NE91_9LACT/504-635        AC H3NE91.1
#=GS K0YDY7_9CORY/196-344        AC K0YDY7.1
#=GS C7HVI4_9FIRM/1143-1298      AC C7HVI4.1
#=GS A0A137SVZ1_9FIRM/4169-4324  AC A0A137SVZ1.1
#=GS CLFA_STAA8/373-525          AC Q2G015.1
#=GS CLFA_STAA8/373-525          DR PDB; 2VR3 A; 373-525;
#=GS CLFA_STAA8/373-525          DR PDB; 2VR3 B; 373-525;
#=GS A0A0R2I985_9LACO/246-396    AC A0A0R2I985.1
#=GS E8SES1_STAPH/433-583        AC E8SES1.1
#=GS U7UL82_9FIRM/4124-4279      AC U7UL82.1
#=GS K9EAH6_9LACT/567-731        AC K9EAH6.1
#=GS Q5HRI6_STAEQ/389-540        AC Q5HRI6.1
#=GS G5KHS3_9STRE/235-396        AC G5KHS3.1
#=GS E4L031_9FIRM/4013-4216      AC E4L031.1
#=GS E8SHD7_STAPH/324-467        AC E8SHD7.1
#=GS E8SH04_STAPH/324-481        AC E8SH04.1
#=GS G5K4P3_9STRE/124-268        AC G5K4P3.1
#=GS H3NL27_9FIRM/1569-1729      AC H3NL27.1
#=GS Q8DYL7_STRA5/475-627        AC Q8DYL7.1
#=GS A0A133Q0B2_STALU/426-574    AC A0A133Q0B2.1
#=GS A0A0A8HSF0_STAHY/295-444    AC A0A0A8HSF0.1
#=GS E0NIX5_9FIRM/4508-4663      AC E0NIX5.1
#=GS K1M3I9_9LACT/291-412        AC K1M3I9.1
#=GS SDRD_STAA8/397-559          AC Q2G0L4.1
#=GS H3NQ17_9FIRM/296-457        AC H3NQ17.1
#=GS FNBA_STAA8/341-496          AC P14738.1
#=GS FNBA_STAA8/341-496          DR PDB; 4B60 B; 341-496;
#=GS FNBA_STAA8/341-496          DR PDB; 4B60 A; 341-496;
#=GS FNBA_STAA8/341-496          DR PDB; 4B5Z A; 341-496;
#=GS C7REI7_ANAPD/4217-4382      AC C7REI7.1
#=GS A0A133ZHK0_9BACL/156-310    AC A0A133ZHK0.1
#=GS F2I830_AERUA/337-501        AC F2I830.1
C8PC72_9LACO/125-277                   ........gqd--NLNSNGTA....NLFDIDEST..GTYKETIYVNN...KQR.E.Q....N.N.TRI--LIENG................gNDSFTTFD.G...QvV.KSIE............V.YKVKDPS..........KLSGSMDLD..--MDNLE.KV..S.P..........tQY..DQ.............KLKADRSG-.....IELDL.KNQGT....KDVYVV..RYNGKYDSSKNAN.IKTT--.IVADP.QNNP---.........------yevaehfas.......................................................
A0A0X8FKI8_9LACT/443-590               ........idd----------....---AIDKNT..GTFTQYFIVNP...ESK.R.L....Y.G.ANFVANDVTN.................--QGSVIEiD...E.N.SEIT............V.WKAPKGA..........QMPDSVVAD.yDSMSGFQ.RVnvT.K...........--..-Vnreqd..egkngvTSFFGFNESy...pADVRI.TLPST...iDSPYVI..RVKGKTDKTKSND.PNVN--.-----.-------.........------kfisqgqlw.......................................................
C2BGP3_9FIRM/4686-4842                 .........ty--NYWHNLTG....KITEMDKTT..GEFTQYYYINR...MKD.KgW....K.N.WTFRYNPYSS.................-DKTNTKR.L...S.Y.ANVR............V.MKLKDNSdan....iarSMPESFALD.iNNDSNLT.EI..Y.NqrfdrmgatsfNF..SG.............YKEGNQPNG.....YMPNA.GSDE-....GDSYIV..EVKGKIP------.------.-----.-------.........------lseikefesvasii..................................................
SDRC_STAA8/336-485                     ..........g-NKKAQPLIS....STNYINNED..LSRNMTAYVNQ...PKN.T.Y....T.K.QTFVTNLTGY.................-----KFN.P...N.A.KNFK............I.YEVTDQN..........QFVDSFTPD..--TSKLK.DV..T.D...........QF..D-.............VIYSNDNKT.....ATVDL.MKGQTs..sNKQYII..QQVAYPDNSSTDN.GKIDYT.LDTDK.TKYSWSN.........SYSNVN................................................................
A0A0J6WRI6_9FIRM/1-50                  ..........m----------....---------..-----------...---.-.-....-.-.----------.................--------.-...-.-.----............-.-------..........---------..-------.--..-.-...........--..--.............---------.....--VDF.GNI--....NSPYII..KVESKYTPGAEDS.LAIQQG.VRMTT.TNDGILS.........YAGYTN................................................................
A0A133QA33_STALU/357-509               ........gef---RNLSIKG....TIDQIDKVN..NTYRQTVYVNP...SSD.T.V....V.D.PYLRGGSIPG.................TNSNVIID.E...Q.N.TSIK............V.YKVKEKA..........HLTDSYYVD..--PSNYE.DV..T.S...........--..DV.............KITFPEKGI.....YQINF.NTEDDq..iNSPYVV..VINGHVDPNSNGN.LYLRST.LYGYD.SNFTRVS.........-MAWDN................................................................
A0A0A8HP03_STAHY/363-510               ........nlr----GVNING....SIEYLDKNK..NTFKHIAYVNP...SKN.T.V....Y.N.SRLTGNIMNG.................-----APT.T...N.Q.PTVK............I.YKYLGTE..........SLNQSVYVD.tNNSSMFK.DV..T.S...........DF..KD.............RLSINSGG-.....YYVDM.NDL--....SNTYVV..TYEGQYLNNAN-E.LNFRTE.LAGYP.ATYPYYY........tSVKWDN................................................................
H3NIB7_9LACT/317-484                   ........lkg----FPSVGS....LVVSSDLNK..NTFRQIIYVNPlegNQQ.T.T....T.N.TTL--TFSNR.................GNQNSITN.A...A.G.ANIK............I.YKVPTASr........kYMPYSYAYN..--QKTFD.EG..I.Esg......evlDF..SEkf........didRVQRTTESSl..dkFTINF.GTVDP....RDSYVI..VVDGKFIN-----.------.-----.-------.........------ldetndnpqylsqvfydfddikvnkdqn....................................
K1LBH0_9LACT/268-430                   .......tgnn-----LNGMS....QITEFNPET..GEFTQVFYINP...DSK.T.I....T.T.SNRNWATGKVamfid......gltpdkTPSDVNYT.K...E.N.TKVS............I.QKLPSGT..........KLPNAIIEN.pVKTDEQT.MV..K.T...........TF..RDg..........giEITFAENGD.....KNLRH.DNI--....DSPYIV..TVKSIAAPSKTGNnVYSRAT.-----.-------.........------fygdgtrfhvmd....................................................
C0MFY9_STRS7/943-1091                  ......dsysp-----VNIGS....MLTKLDLKQ..ELFTNYVYINP...RHY.S.L....S.N.GRLVFSGQGA.................-----AII.D...E.N.TQVT............L.YLANDAY..........DMPPSWGID..--DKRLI.EE..K.S...........--..--.............-IKINKSLG....rIDIDF.QNRLY...sGQSFIL..KIVGRYDINSDAP.IKTSAT.LYQNY.YNYYGYY.........------tekgrwipq.......................................................
A5VHN3_LACRD/220-387                   ..........a-NDMFLGISS....RMMHFDKDQ..QLFEDIIYVNP...AQK.D.L....N.H.AYIVFNTSDLv...............eELSNAVVK.P...S.T.MRVE............I.YRNSRGL..........KLPQSYGVN..--LQRLR.DI..T.N...........RF..PVvegdh..lveapyTMSFADNK-.....MRLNF.GADQT....NDSYII..RVVGQYNDELDGT.VRLRAR.LFGMD.QQNVYMS.........N-----staatat.........................................................
B9DJ62_STACT/567-737                   .........ds--QLSSNIDS....FITHTDQAT..GDYQQVIYVNP...QGK.E.A....Y.N.TKV--NLYNYwpn..........qntpGDSSAQLN.P...D.V.TSYK............I.YEVRNGQ..........EMYPSYYLD..ENNPNLV.DV..T.Dwnn.....qdyNF..NP.............TYSTDANGGe...vLTLDF.QNLTS...nGSQYII..VLDSKSENGNRES.IKTRVE.MSSDV.TPDGQGH........nYYTWDN................................................................
G5KI16_9STRE/349-505                   .........vg--NQDLQINS....RIVQQDETT..QTVTYNTLVNP...NGN.N.L....T.T.SYHYY--SEItnvtn......tddgtgHIITSTVN.L...R.D.ATVQ............I.YRGTTT-..........TIGQSINPD..--LSTLT.DV..T.D...........VY..S-.............-HTVDQYGN.....IVIDW.GNNAFsdtnNNVYMI..VVKASYNNTED--.IGLVS-.-----.-------.........------sletivlnrykfaa..................................................
A0A0A8HPX7_STAHY/420-571               .......vyps------SVDT....MITRVDGTEknNTFTEVIYVNP...KNV.D.L....S.A.ARL-IMGKDT.................PNSNALID.Y...N.T.TNFH............I.YQVPDPS..........VLTDSYYFN..--PAGYQ.DL..A.P...........EF..YQn...........gWIYTNLDGN.....LEIDF.GAI--....RTPFVV..VMDAHFDPNHSND.LSTRAT.LIATD.QKNYTSN.........-YNFDN................................................................
C7XUD1_9LACO/271-411                   .......qnda----QYGFSA....RIYDIDFSN..GKYKVNAYFNA...QNK.P.L....D.N.QQI--EIWAR.................GDNNTDLN.P...K.S.CTFR............V.YRVKDGK..........TLNASLIPD..--YSEYD.DI..T.N...........QL..KIstneadaetpgvlYYD-AATNT.....VKINF.GGKQD....SNAYIL..HFEGQS-------.------.-----.-------.........------pvkngkvh........................................................
H3NL27_9FIRM/739-898                   ......npsnp-----INIDT....SFYYTNDQN..GKYTQLVYVNP...LKN.N.I....NiS.TNLEITPYINhqgv.........dksiDNIVANID.P...I.N.TTIK............I.YKLKDVN.........aKFDQAVIFD..--ETKLI.DV..T.T...........QF..NG.............KINIINGK-.....ATISF.SKPIN....SESYLV..KIDSNMKY-----.------.-----.-------.........------ptgviqgtflaqtavlrssnayvski......................................
A0A0A8HQN5_STAHY/288-443               ....kdnygfn-----MEVNG....RLSSINKEN..QSFTHIAYINP...NEK.F.M....N.N.IRITGSFENG.................----APIK.K...Q.K.PILK............I.FKYNGEK..........PLAQSVYIN..FNTDKLV.DV..T.E...........--..EL.............SPILNENGN.....YSFKI.DNLN-....GEIFIV..KYDGFYNGSDT-A.LKFRTE.LDGYHySSNQYHYnk....kfsKLTWDN................................................................
V4QRG6_STRIN/350-509                   ........qhg----NYNVDS....RIIKANFTD..FSFKYVTQINP...LGK.L.I....S.T.SNFSPLVSVIq...............nADQDSHID.L...S.K.VNYK............I.YKLIGSD..........LLSESMNED.yLNTNKFE.DV..T.Q...........NF..RS.............EFNSEANA-.....RVIYW.DKSYI....QEKFII..VVEGSAEKDSK-T.LSVSTT.IEPLN.SY-----.........------yqegvkyaagvrlyg.................................................
Q2G1T5_STAA8/291-439                   ..........r-DNWGVTANG....RIDTLNKVD..GKFSHFAYMKP...NNQ.S.L....S.S.VTVTGQVTKG.................----NKPG.V...N.N.PTVK............V.YKHIGSD..........DLAESVYAK.lDDVSKFE.DV..T.D...........NM..S-.............-LDFDTNGG.....YSLNF.NNLDQ....SKNYVI..KYEGYYDSNAS-N.LEFQTH.LFGYY.NYYYTSN.........-LTWKN................................................................
A0A0A8HSB6_STAHY/274-424               ..........r-DNNGMRING....RIDRLDKNN..GTINHIAYINP...EKK.N.M....V.A.VSVTGRITEG.................----HSKG.D...E.R.PNIK............I.YKYKGQS..........NLAKSVYVD..FNNADFE.DV..T.N...........NM..K-.............-LSILDGS-.....YKLDF.ERLN-....GETYVI..QYYGKYDVNAA-N.LNLQTQ.LSGYY.YYNNHYYyy.....psTLTWDN................................................................
CLFB_STAA8/367-524                     ..........d-KPNGANISS....QIIGVDTASgqNTYKQTVFVNP...KQR.V.L....G.N.TWV--YIKGYqd.............kiEESSGKVS.A...T.D.TKLR............I.FEVNDTS..........KLSDSYYAD..PNDSNLK.EV..T.D...........QF..KN.............RIYYEHPNV.....ASIKF.GDI--....TKTYVV..LVEGHYDNTGK--.-NLKTQ.VIQEN.VDPVTNRd......ysIFGWNN................................................................
A0A0A8HPX0_STAHY/354-505               ........iyp-----ASVDT....MITSVDGTEttNTFKETIYVNP...KDV.D.L....S.G.ARLLLGTDT-.................PNSNAIIN.Y...D.T.TKLH............I.YRVSDPN..........QLTDSYYFD..--PTGYP.DL..A.Q...........SFydSK.............RIYMNSDGN.....LEVNF.GGI--....DTPYVV..IMESQFNPNHSND.LSTRAT.LIATD.LNNYTAK.........-YYFDN................................................................
F9MW46_9FIRM/277-448                   ......elssd-----VNGKS....QFIAYNPKT..GEFTQVFYLNP...ESK.E.I....T.P.STT--DDQNGrqmgkvgfllssphdadKPRSVDYL.A...N.N.TKIE............V.KKLPKGA..........KLPDAIIEN.pEGAQPAT.NV..K.G...........EF..R-.............--NFKGEPM.....FTMNF.GNGNK...iDSPYVV..VVKGHANEIDGKY.TELYSN.G----.-------.........------tlygdgeaslfldnsytvq.............................................
A0A0D6XSV0_9STAP/352-507               ........vyf----GANTTS....TITDIDVDSgkNEYKQTVYVNP...MGH.D.A....R.G.TML--TIQGYke.............dpTKSATVIS.Q...D.K.TNLR............I.YEVKDRT..........KITDSYYID..PNNPNYI.DV..T.D...........DV..LP.............YVTYNNDNS.....LSINF.GDI--....TKTYAI..TVDGHYVKNGE-N.VRTRVI.METVE.RETGDRS.........SFYWDN................................................................
F0H0K9_9FIRM/4138-4300                 ........aei---YGLNMTS....KIVSFDRES..GEFVQYFYINR...NMN.Q.S....SdP.VTFRYKPSED.................---VKNLR.V...D.V.INLKq..........nG.YDNNNRQgetnkefvnrDMPESFGVN..ESSDNLN.WH..S.W...........--..YG.............YYQPKADEN.....VDITL.GPYNQ....YDSLIL..KVTGQVDKKDIAS.YDTYAK.LFNKV.YTYDYYG.........------nvtnv...........................................................
G4D2J9_9FIRM/1034-1187                 .........ss--NDGLNMNA....SFDYTNDQN..GKYSQVIYVNQ...KGS.N.I....T.V.PTH-LEITPYvds..........nyknGYIKANIS.P...I.A.TAIK............V.YKVKSGQ..........SLSNAVIYE..--KDKLE.DV..T.D...........QF..KD.............KIKIDYGK-.....ATVQF.DNIG-....TDKYVV..VVDSNM-------.------.-----.-------.........------iypqgqiqgtylaqvaslvnnnpssrv.....................................
B0S003_FINM2/4232-4393                 ........egg---NTPNMTS....KIVSFDRET..GEFVQYYYINR...DKT.L.T....K.S.AEFEYTPSEA.................--------.-...-.V.TNLKfdyyalrqnsgnI.YDYNKGQyvd...pivkDMPESFGVD..ENSYNLN.WY..Y.T...........--..DG.............YYNLGAGQT.....QKISL.GTLGK....DNSLIL..KVTGKVKAENIAS.YDTYAK.MYGYY.TEKWTDY.........-YGYSH................................................................
A0A033U795_STAAU/464-618               .........ga---NGANISS....NINKIDNKSgeRTYKQVIYVNP...LAK.Q.L....Y.G.SNV--NVKGYyd.............dpTVSSTLVN.S...D.N.TRYK............I.YEVINPN..........LLNESYFVD..PNDGNFK.DV..T.A...........NF..NG.............YITDNNDNS.....TDIKF.GDI--....NKAYVI..LVDGHYDESEN--.-DVLTR.VTETN.RDYYGNP........sSFYWDN................................................................
H3NE91_9LACT/504-635                   qlngsrafvkv----------....------NSD..GNYRHVTYFNP...QKN.S.L....N.N.VQIEGVALGA.................----GTLN.S...E.N.STVK............L.YKVKDNR..........RLADSISANnyNDTTIFE.DV..T.R...........NY..PTlnqfe...dvsfsGGKLTGKST.....GKANL.GNI--....NETYVM..VVDSKAKDD----.------.-----.-------.........------gtl.............................................................
K0YDY7_9CORY/196-344                   .........vd---RSLSLKS....HLYNVDPEA..GTYTVNSVVNP...YGQ.K.I....T.N.AVLFGGPQPD.................-RETSAVF.G...G.D.VDVK............V.YRIDDPK..........DVPDSVVTD..-DVSEFV.DV..T.D...........--..QV.............KKNSSRGEG.....YEIHF.PET-I....DTPYLV..VYNGTFDPSSDVP.LNTRHT.FEGC-.-------.........------hefagfdfmywdn...................................................
C7HVI4_9FIRM/1143-1298                 .........vg--NTHLNMAS....KITSFDVKT..GKFEQYFYINK...LRK.T.S....G.P.LNFYYRPNQL.................------VT.N...L.E.IETQ............A.LNNNSGQni......nlYMPESFGVN..DNSPGTT.KY..H.K...........AY..WE.............SVAQGGSAN.....YRLES.SNVSQ....NDSYIV..KVTGYLKVGEETD.YESTVY.LEDAI.TRY----.........------yvqrvnsiyvfk....................................................
A0A137SVZ1_9FIRM/4169-4324             ........ngd----QVSMSS....KITEFNPDT..GEFTQIFYINP...SRN.N.A....G.F.DYDGNSIPTYfnyyp.......gkgvdDLRISAYW.Y...D.N.SSYN............D.YDYTNTFl.......neKMPASYGLD..-LSKETL.WN..T.K...........-F..YG.............RTVTDYNNG.....-WMKF.SRMNK....TDSYVV..KVTGRIADGQD-K.TSF---.-----.-------.........------tpranlinykggg...................................................
CLFA_STAA8/373-525                     .........gk--FYNLSIKG....TIDQIDKTN..NTYRQTIYVNP...SGD.N.V....I.A.PVLTGNLKPN.................TDSNALID.Q...Q.N.TSIK............V.YKVDNAA..........DLSESYFVN..--PENFE.DV..T.N...........--..SV.............NITFPNPNQ.....YKVEF.NTPDDq..iTTPYIV..VVNGHIDPNSKGD.LALRST.LYGYN.SNIIWRS.........-MSWDN................................................................
#=GR CLFA_STAA8/373-525          SS    .........EE--ETTEEEEE....EEEEEETTT..TEEEEEEEEST...T--.-.E....E.E.EEEEEEE-TT.................S---EE-S.T...T.T.-EEE............E.EE-S-GG..........GS-SS----..--GGGSE.E-..G.G...........--..GS.............EEEEEETTE.....EEEE-.----SE..E-S-EEE..EEEEEE-TT-SS-.-EEEEE.EEEE-.TT--EEE.........-EEEEE................................................................
A0A0R2I985_9LACO/246-396               .....dpsaaa------NGEA....FITALDRTN..KEMTSVIYANP...IGN.V.I....Q.S.PWV--KVENL.................NNSKVNYN.N...R.D.TNVT............V.YQLKPGY..........DPTQSFYID..--PASVN.DV..T.G...........--..QV.............RIVFQDNK-.....MYIQF.PTSSSg.tnWSKYII..KYTTTYDDSSTKQ.INTRTT.NYSGT.YSNNYMY.........---WDNhd..............................................................
E8SES1_STAPH/433-583                   .........vg----DSNLKS....MITMEDSKT..GEYEQYIYVNP...LKR.D.A....Y.G.TVV--RVQGFqn.............dpATSNGQVN.P...D.T.TQIK............I.LKVSDGQ..........TLNSSFGVD..--DSQYE.DV..T.D...........KF..K-.............TVYRDGENL.....ADIFL.GDLN-....GARYII..KVTSKEVSGSSED.LKLRSS.MYTKN.TYGQYDR.........-LTWDN................................................................
U7UL82_9FIRM/4124-4279                 .........gn----NLNMTS....KIVSYDPNT..GDFVHYYYINR...NKT.S.N....T.G.CDF--YYY--.................------PN.Q...D.V.KDLE............IrYIKLKNNad.....vstDMPESFGLD..ETSNNL-.EI..S.R...........VM..RS.............RTLLRVNER.....EDLNFtGGIGK....GDSYII..KVTGRVAGEDKT-.------.-----.-------.........------ayggagelkavysdggtvkvsrwdkvysfkn.................................
K9EAH6_9LACT/567-731                   ......rrngp-----ASTSS....VINWVDDKT..NTFRATAYFNI...DNN.Y.I....G.T.EGRVFYITATeg.............tePGAPNAIN.M...D.S.LDIR............V.YRVSDGR..........VLPESRAFD..PVAVGAE.DI..T.D...........QV..NV.............ESYLTSDNAtedgdYWIDA.PTNN-....SDTYIM..VVHGTFDPDRL--.------.-----.-------.........------gpqgefgmqvqsndvdyetgqqaghts.....................................
Q5HRI6_STAEQ/389-540                   ..........n-ENRTANLQS....MFTNIDTKN..HTVEQTIYINP...LRY.S.A....K.E.TNV--NISGN.................GDEGSTII.D...D.S.TIIK............V.YKVGDNQ..........NLPDSNRIY..-DYSEYE.DV..T.N...........--..DD.............YAQLGNNND.....VNINF.GNI--....DSPYII..KVISKYDPNKDDY.TTIQQT.VTMQT.TINEYTGe......frTASYDN................................................................
G5KHS3_9STRE/235-396                   ........vyg----TSSIQT....VFNEVDTTN..NTVEQIIYINT...NNA.Y.S....G.A.TAYNNILSIYggll........qngtiVENGSETV.N...N.T.STIE............I.YEAGNGS..........TLPKSMKIT..-DYSNFK.KV..D.S...........DT..IA.............SNSTYYSDR.....VDIDF.GDI--....NTAYVI..RVVSSYDANSTDN.LVQSAN.MYSRD.ASGT---.........------vfnyynteas......................................................
E4L031_9FIRM/4013-4216                 ........dkv---SFMNLGS....KITKFNPET..GEFVHYYYINR...DKE.N.I....G.A.SKFIYHSDQN.................-----IKN.F...K.I.TGID............I.TDNKNID.........dVMPESFGLD..EDNSNYK.AK..E.L...........--..VS.............LQYLSKGKE.....AVLNF.KEGFK...eNESYII..KVTGNVSDTNKMA.YVGHGK.LDRTY.QT-----.........------agyflyvtrkdqvygfanstnakadlsiqavnpenkirflkvdqdgkplkgasfslniqdkdgn
E8SHD7_STAPH/324-467                   .....yydnsh------YVDG....RISQVNKKE..AKFQQIAYINP...NGY.L.N....G.R.GTIAVNGEVV.................--SGTTKD.L...M.Q.PTVR............V.YQYKGQG..........VPPESITID..--PNMWE.EI..S.I...........--..--.............TMVRKYDGG.....YSLNL.DTS-K....NQKYAI..YYEGAYDAQAE-T.LLYRTY.I----.-------.........------qslnsyypfsyqkmn.................................................
E8SH04_STAPH/324-481                   .........ks--PSGITLNG....RLDELSKAD..QSFTHYAIFKP...KHN.N.L....T.N.VTLRGTVSNN.................----AQQN.E...K.N.GQVN............V.YEYIGQG..........ELPQSAYAN.vKDTNQFR.DI..T.N...........--..SL.............RPTTVNSTG.....YQITF.DHIN-....KKPYVI..VYKGHYKNEAK-D.LEFTTN.ATDYH.SSNLYSYnywpyygsfNLTWKN................................................................
G5K4P3_9STRE/124-268                   .......dthn----PVNIGS....MITSLDEAT..GDFVNYIYVNP...LGK.R.L....E.Q.TQLTYTG---.................--SGSTII.N...Q.D.TRVQ............V.FEVSYPT.........vQMPPSWGVD..--DKSMR.EV..F.D...........--..-T.............NISKSDGR-.....ILIDF.YDDLL...yGKSYIV..KISGKSDLKNSDP.IHTEAV.LQQRY.FNYYS--.........------ywmesg..........................................................
H3NL27_9FIRM/1569-1729                 .......ydnv-----SGLGS....TITEYDGSK..SYYKHVVYLNP...YGS.R.M....Y.Y.GDR--TVLSYifd...........tngDKNSSAIV.N...N.T.TKMD............L.YLVNNLS..........DFAESYSFD.tNGKYKLR.EG..V.D...........--..--.............YIRQNYNGT.....VEINF.INYKPi..dGYKIAL..VVDGKMDMDSDKP.LNPSVK.LYN--.-------.........------awieydvygnqveynhwh..............................................
Q8DYL7_STRA5/475-627                   ..........h-TNVKTNVRS....RIMKLDDER..QTETYITQINP...EGK.E.M....Y.F.ASGLGNLYTIig.............sdGTSGSPVN.L...L.N.AEVK............I.LKTNSK-..........NLTDSMDQN..YDSPEFE.DV..T.S...........QY..S-.............--YTNDGSK.....ITIDW.KTNSIs..sTTSYVV..LVKIPKQSG----.-VLYST.VSDIN.QTYGSKY.........SYGHTN................................................................
A0A133Q0B2_STALU/426-574               ..........g-DNKNNPLNA....STLYRDPKT..NQQYRIIYINE...PGK.T.Y....K.N.VKYHSTTMNG.................-----KLI.D...G.T.DAIK............V.YKVNDPS..........AMVNSFAPD..LTSSKVT.DV..T.S...........--..SK.............TITYDNNRS....tVNVSL.GNLDG....KTRYIIaeKVEPTTDNGNL-S.STFSIT.NDDKN.N------.........------ptiwaasttq......................................................
A0A0A8HSF0_STAHY/295-444               .......rtgs----GVKVNG....RIHRLDKDN..RIFTHIAYINP...DKK.H.L....N.A.VDVVGYFRKG.................----GTHV.S...R.P.KNVQ............I.YEYVGKH..........PLAQSVYAD..FNVDDYK.EV..T.K...........--..NV.............NLIVQENGQ.....YKATL.GNLN-....GKTYVI..RFDGQYHENAN-D.LSFATE.LTGHH.LVNGYYVp.......tKLTWLN................................................................
E0NIX5_9FIRM/4508-4663                 .........yd--NATVSLAS....KITQYNTKT..GEFVHYFYVNR...DRQyN.N....K.D.QYFTYTPNVA.................--------.V...D.D.LQLT............Y.YKLRYNSeyy....inqSMPESFAVN..ESDSNLV.RS..G.G...........--..TS.............PEDVAANKK.....VTYNI.GNLGP....KGSMII..KVTGRMKATGTEK.QVLSYKgVSGLY.SKYYYYY.........------dywgnyig........................................................
K1M3I9_9LACT/291-412                   ..snvlyevid----------....--------S..RDYTNISYFNP...TFN.Q.L....Q.S.GTY-GLIYPF.................KTSDSAIN.PmefE.K.AKVT............I.YEVSEGN..........KLNESHYFV..PEEVNAV.DV..T.N...........--..DV.............NLTFDQSSN....gWRFDL.INP--....NKSYVA..VTKGKA-------.------.-----.-------.........------rqllpge.........................................................
SDRD_STAA8/397-559                     .........vv--NEKNSIGSafteTVSHVGNKEnpGYYKQTIYVNP...SEN.S.L....T.N.AKL--KVQAYhs.............syPNNIGQIN.K...D.V.TDIK............I.YQVPKGY..........TLNKGYDVN..--TKELT.DV..T.N...........QY..LQ.............KITYGDNNS.....AVIDF.GNA--....DSAYVV..MVNTKFQYTNSES.PTLVQM.ATLSS.TGNKSVSt......gnALGFTN................................................................
H3NQ17_9FIRM/296-457                   ..........t-DNNGTNIGS....AIASVNTND..NTFTQIIYVNR...YIG.S.TppylG.S.LKLNYNIYSD.................-----SAI.T...N.V.TSVE............A.YKIKDAYfsy....istLMPTSFNPD.lSDTRYYEkDY..V.N...........--..--.............--VSGAGIS.....KSITF.GPNTGy..iNNPYII..KIMGTYNEKST--.YPIRST.SNIEN.TRYGYSY.........-LGN--asitttvn........................................................
FNBA_STAA8/341-496                     .........ig--NYYANLNG....SIETFNKAN..NRFSHVAFIKP...NNG.K.T....T.S.VTVTGTLMKG.................----SNQN.G...N.Q.PKVR............I.FEYLGNN.........eDIAKSVYAN.tTDTSKFK.EV..T.S...........NM..SG.............NLNLQNNGS.....YSLNI.ENL--....DKTYVV..HYDGEYLNGTD-E.VDFRTQ.MVGHP.EQLYKYYyd....rgyTLTWDN................................................................
#=GR FNBA_STAA8/341-496          SS    .........EE---SSEEEEE....EEEEEETTT..TEEEEEEEEEE...-SS.-.E....E.E.EEEEEEEEES.................------TT.S...-.-.-EEE............E.EEE-S-G.........GGS-TT----.TT-TTTEE.E-..G.G...........GH..GG.............GEEE-TTS-.....EEEEE.EEE--....SS-EEE..EEEEE--TT-S-C.EEEEEE.EEEEC.----SS---....--EEEEEEE................................................................
C7REI7_ANAPD/4217-4382                 ........aei---YGLNMTS....KIVSFDRES..GEFVQYFYINR...NMN.Q.S....K.DpVTFRYKPSEDv...............kNLRVDVIN.L...K.Q.NGYN............Y.YNYNTRKkgtiqdfvnqDMPESFGVD..ESSDNLN.WH..S.W...........--..YG.............YYQPKADEN.....VDITL.GPYNQ....YDSLIL..KVTGQVDKKDIAS.YDTYAK.LFNKV.YTY----.........------drygnvtnv.......................................................
A0A133ZHK0_9BACL/156-310               .avdidsnsva----------....TLYDINEQA..GTYKETIYVNN...QGK.P.Q....N.G.TKM--IIENG................gQDSFTTFD.G...Q.VlNSVK............V.YKVKDPY..........NLKGSMDYD..--AENLE.EL..KpS...........QF..EK.............KLKDDHSG-.....IEINL.QNKGS....KDVYVI..HYSGKYDASKTAN.VKTTAI.ADPEN.KPTETA-.........------shiasvsl........................................................
F2I830_AERUA/337-501                   ........rkg----RLNINS....QFTEWNKDT..GEFTQVFYVNP...KSE.T.I....R.S.G-LNGSFENSvgmvvhnggreannilgAPSDVYYD.A...D.N.TKVE............I.KKIPRGT..........NLPDAVYED..----PVA.GV..L.D...........K-..DS.............EINYNNGQ-.....LYIDF.KKRQI....DSPYVV..VVKSKAKSHNGVD.YNLYSS.GVLHG.D------.........------dgipgdiyswve....................................................
#=GC SS_cons                           .........EE--ETTEEEEE....EEEEEETTT..TEEEEEEEECC...TSS.-.E....E.E.EEEEEEEECT.................S---EETT.T...T.T.-EEE............E.EEESSGG.........GGS-TT----.TT-CCCCE.E-..G.G...........GH..GC.............CEEEECTTE.....EEEEE.EEE-SE..ESS-EEE..EEEEEE-TT-SSC.EEEEEE.EEEEC.TT--CCE--....--EEEEEEE................................................................
#=GC seq_cons                          ..........s....thslso....pIsphDpps..spapphhYlNP...ppp.s.h....s.s.sph.hphpsh...................t.sths.s...p.s.sslc............l.Yclpssp..........plscShhhD....ssphp.-V..o.s...............p..............phphsssss.....hplsa.ssht.....sssYll..plsGphcsssp.s.hphpsp.h.t.........................................................................................
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