GenomeNet

Database: Pfam
Entry: SelP_N
LinkDB: SelP_N
Original site: SelP_N 
#=GF ID   SelP_N
#=GF AC   PF04592.12
#=GF DE   Selenoprotein P, N terminal region
#=GF AU   Kerrison ND
#=GF SE   DOMO:DM04433;
#=GF GA   23.20 23.20;
#=GF TC   23.80 24.40;
#=GF NC   23.10 23.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Selenoprotein_P
#=GF RN   [1]
#=GF RM   10775431
#=GF RT   Selenoprotein P: properties, functions, and regulation. 
#=GF RA   Mostert V; 
#=GF RL   Arch Biochem Biophys 2000;376:433-438.
#=GF RN   [2]
#=GF RM   11168591
#=GF RT   Selenium metabolism in zebrafish: multiplicity of selenoprotein
#=GF RT   genes and expression of a protein containing 17 selenocysteine
#=GF RT   residues. 
#=GF RA   Kryukov GV, Gladyshev VN; 
#=GF RL   Genes Cells 2000;5:1049-1060.
#=GF RN   [3]
#=GF RM   9358058
#=GF RT   Analysis of bovine selenoprotein P-like protein gene and
#=GF RT   availability of metal responsive element (MRE) located in its
#=GF RT   promoter. 
#=GF RA   Fujii M, Saijoh K, Kobayashi T, Fujii S, Lee MJ, Sumino K; 
#=GF RL   Gene 1997;199:211-217.
#=GF DR   INTERPRO; IPR007671;
#=GF CC   SelP is the only known eukaryotic selenoprotein that contains
#=GF CC   multiple selenocysteine (Sec) residues, and accounts for more
#=GF CC   than 50% of the selenium content of rat and human plasma [1]. 
#=GF CC   It is thought to be glycosylated [2].  SelP may have antioxidant
#=GF CC   properties.  It can attach to epithelial cells, and may protect
#=GF CC   vascular endothelial cells against peroxynitrite toxicity [1].
#=GF CC   The high selenium content of SelP suggests that it may be
#=GF CC   involved in selenium intercellular transport or storage [2]. The
#=GF CC   promoter structure of bovine SelP suggest that it may be
#=GF CC   involved in countering heavy metal intoxication, and may also
#=GF CC   have a developmental function [3]. The N-terminal region of SelP
#=GF CC   can exist independently of the C terminal region.  Zebrafish
#=GF CC   selenoprotein Pb (Swiss:Q98SV0) lacks the C terminal Sec-rich
#=GF CC   region, and a protein encoded by the rat SelP gene and lacking
#=GF CC   this region has also been reported [2]. N-terminal region
#=GF CC   contains a conserved SecxxCys motif, which is similar to the
#=GF CC   CysxxCys found in thioredoxins.  It is speculated that the N
#=GF CC   terminal region may adopt a thioredoxin fold and catalyse redox
#=GF CC   reactions [2]. The N-terminal region also contains a His-rich
#=GF CC   region, which is thought to mediate heparin binding.  Binding to
#=GF CC   heparan proteoglycans could account for the membrane binding
#=GF CC   properties of SelP [1].  The function of the bacterial members
#=GF CC   of this family is uncharacterised.
#=GF SQ   116
#=GS G1KQP6_ANOCA/26-179       AC G1KQP6.1
#=GS A0A0B2VN39_TOXCA/20-211   AC A0A0B2VN39.1
#=GS U6P7T9_HAECO/21-226       AC U6P7T9.1
#=GS H0ZC10_TAEGU/1-47         AC H0ZC10.1
#=GS A0A0N5CWJ2_THECL/12-184   AC A0A0N5CWJ2.1
#=GS H2SF16_TAKRU/1-110        AC H2SF16.1
#=GS E0CZ76_MOUSE/23-124       AC E0CZ76.1
#=GS A0A067R8W1_ZOONE/3-168    AC A0A067R8W1.1
#=GS Q7Q0I7_ANOGA/166-293      AC Q7Q0I7.4
#=GS F6V1E8_ORNAN/23-255       AC F6V1E8.2
#=GS U6PFR9_HAECO/21-220       AC U6PFR9.1
#=GS G3W9K6_SARHA/23-176       AC G3W9K6.1
#=GS V4A4R8_LOTGI/1-157        AC V4A4R8.1
#=GS W5JI27_ANODA/146-291      AC W5JI27.1
#=GS G3ID68_CRIGR/21-166       AC G3ID68.1
#=GS G1KY65_ANOCA/23-58        AC G1KY65.1
#=GS G1LAZ4_AILME/4-242        AC G1LAZ4.1
#=GS W5L435_ASTMX/10-143       AC W5L435.1
#=GS SEPP1_PONAB/23-249        AC Q5R8W9.2
#=GS H1A5G2_TAEGU/1-124        AC H1A5G2.1
#=GS E9QB63_DANRE/23-254       AC E9QB63.1
#=GS SEPP1_RAT/23-248          AC P25236.2
#=GS A0A0M3JSD2_ANISI/1-103    AC A0A0M3JSD2.1
#=GS G3PMU8_GASAC/1-188        AC G3PMU8.1
#=GS G3NUN5_GASAC/1-216        AC G3NUN5.1
#=GS D6REX5_HUMAN/23-249       AC D6REX5.1
#=GS A0A0N4U327_DRAME/1-155    AC A0A0N4U327.1
#=GS A0A0G2JU99_RAT/23-203     AC A0A0G2JU99.1
#=GS W5MN82_LEPOC/23-267       AC W5MN82.1
#=GS A0A090LRH7_STRRB/44-214   AC A0A090LRH7.1
#=GS F6VJE4_XENTR/25-266       AC F6VJE4.1
#=GS W4Z1T3_STRPU/83-177       AC W4Z1T3.1
#=GS U3K9A0_FICAL/19-264       AC U3K9A0.1
#=GS A0A0K0EXH8_9BILA/65-243   AC A0A0K0EXH8.1
#=GS F1RD74_DANRE/28-263       AC F1RD74.1
#=GS U3JR44_FICAL/27-249       AC U3JR44.1
#=GS V8NYH9_OPHHA/29-180       AC V8NYH9.1
#=GS G3UU18_MELGA/1-166        AC G3UU18.1
#=GS U3IXD6_ANAPL/13-195       AC U3IXD6.1
#=GS A0A0D9RW51_CHLSB/1-190    AC A0A0D9RW51.1
#=GS W4X313_ATTCE/135-288      AC W4X313.1
#=GS R4GMT5_HUMAN/23-77        AC R4GMT5.1
#=GS W5PG55_SHEEP/23-207       AC W5PG55.1
#=GS V8PHU7_OPHHA/20-55        AC V8PHU7.1
#=GS E2AE76_CAMFO/129-280      AC E2AE76.1
#=GS A0A044QQ64_ONCVO/31-263   AC A0A044QQ64.1
#=GS E0CX80_MOUSE/23-139       AC E0CX80.1
#=GS B0W3C3_CULQU/144-295      AC B0W3C3.1
#=GS E0CY03_MOUSE/33-110       AC E0CY03.1
#=GS A0A085N189_9BILA/40-225   AC A0A085N189.1
#=GS M4A9J5_XIPMA/5-210        AC M4A9J5.1
#=GS Q16FG7_AEDAE/94-251       AC Q16FG7.1
#=GS M3XHZ2_LATCH/1-183        AC M3XHZ2.1
#=GS SEPP1_MOUSE/23-268        AC P70274.3
#=GS F4X476_ACREC/178-323      AC F4X476.1
#=GS A6GDZ9_9DELT/130-246      AC A6GDZ9.1
#=GS A0A087XRM9_POEFO/1-178    AC A0A087XRM9.2
#=GS J0XLE8_LOALO/31-255       AC J0XLE8.1
#=GS M3YSM4_MUSPF/1-167        AC M3YSM4.1
#=GS A0A084VVU1_ANOSI/272-443  AC A0A084VVU1.1
#=GS F7EK34_ORNAN/12-166       AC F7EK34.1
#=GS A0A085N189_9BILA/333-475  AC A0A085N189.1
#=GS J9NST4_CANLF/1-138        AC J9NST4.1
#=GS R4GJB1_CHICK/1-203        AC R4GJB1.1
#=GS G3TLW1_LOXAF/23-207       AC G3TLW1.1
#=GS SEPP1_BOVIN/23-290        AC P49907.2
#=GS A7RTX8_NEMVE/23-190       AC A7RTX8.1
#=GS F4X476_ACREC/858-966      AC F4X476.1
#=GS A6FZW7_9DELT/137-264      AC A6FZW7.1
#=GS H2UNP3_TAKRU/23-253       AC H2UNP3.1
#=GS A0A077ZBY8_TRITR/1-193    AC A0A077ZBY8.1
#=GS H3DGX7_TETNG/23-251       AC H3DGX7.1
#=GS F6PUF8_HORSE/23-250       AC F6PUF8.1
#=GS G5APA7_HETGA/37-233       AC G5APA7.1
#=GS J9FD25_WUCBA/10-174       AC J9FD25.1
#=GS M4ANC2_XIPMA/23-205       AC M4ANC2.1
#=GS F1N9T1_CHICK/1-159        AC F1N9T1.2
#=GS A0A0R4IUA1_DANRE/28-262   AC A0A0R4IUA1.1
#=GS H3DJR4_TETNG/1-201        AC H3DJR4.1
#=GS E0CZC5_MOUSE/23-177       AC E0CZC5.1
#=GS H3CE96_TETNG/6-134        AC H3CE96.1
#=GS H2PXQ5_PONAB/1-188        AC H2PXQ5.2
#=GS A0A0N4WS67_HAEPC/21-240   AC A0A0N4WS67.1
#=GS G1Q9G6_MYOLU/23-202       AC G1Q9G6.1
#=GS F6Q9N1_XENTR/23-205       AC F6Q9N1.1
#=GS A0A0K0JE39_BRUMA/7-208    AC A0A0K0JE39.1
#=GS I3JR88_ORENI/1-180        AC I3JR88.1
#=GS D6RIS9_HUMAN/23-209       AC D6RIS9.1
#=GS W5KEM0_ASTMX/23-259       AC W5KEM0.1
#=GS A0A088AAX3_APIME/26-230   AC A0A088AAX3.1
#=GS A0A0P7ZE00_9TELE/1-115    AC A0A0P7ZE00.1
#=GS A0A096MFI7_POEFO/5-209    AC A0A096MFI7.1
#=GS C3YH40_BRAFL/68-195       AC C3YH40.1
#=GS A0A0P7UJP5_9TELE/61-206   AC A0A0P7UJP5.1
#=GS A0A093BFN6_CHAPE/1-116    AC A0A093BFN6.1
#=GS SEPP1_HUMAN/23-249        AC P49908.3
#=GS H0UZB3_CAVPO/1-141        AC H0UZB3.1
#=GS E5SI43_TRISP/46-261       AC E5SI43.1
#=GS I3LJP2_PIG/5-135          AC I3LJP2.1
#=GS A0A096M0U7_POEFO/1-106    AC A0A096M0U7.1
#=GS B7Q2F3_IXOSC/1-206        AC B7Q2F3.1
#=GS A0A0J7NEP2_LASNI/96-254   AC A0A0J7NEP2.1
#=GS H2MB78_ORYLA/1-159        AC H2MB78.1
#=GS SELPA_DANRE/23-255        AC Q98SV1.3
#=GS K7E6A4_MONDO/1-186        AC K7E6A4.1
#=GS K7JYM3_NASVI/162-308      AC K7JYM3.1
#=GS W5M4W3_LEPOC/1-173        AC W5M4W3.1
#=GS A0A0N5DGW6_TRIMR/275-459  AC A0A0N5DGW6.1
#=GS W5MN70_LEPOC/1-198        AC W5MN70.1
#=GS A0A096M1E4_POEFO/1-185    AC A0A096M1E4.1
#=GS SELPB_DANRE/28-263        AC Q98SV0.3
#=GS I3KDC0_ORENI/1-102        AC I3KDC0.1
#=GS U3KMC5_RABIT/1-197        AC U3KMC5.1
#=GS H2ZVW4_LATCH/23-227       AC H2ZVW4.1
#=GS G3WG53_SARHA/1-198        AC G3WG53.1
#=GS A0A0N5B269_STREA/64-247   AC A0A0N5B269.1
G1KQP6_ANOCA/26-179                  ..............................................n-KTRICQPAPLWKIN.GTAPMAGMEG..QVTVVALLKAS...M..LV.IS.LP.AISIGGL....QKKLSNEGVANVSFLIV............N..........EK.TPLSRAMYWE.LKRNA.PQ....GIP......VYQ...QQIL.EPDVWQ.ILDGD...KDDFLIY..D.....RCSRLTF.HIQL..PY...S.FL...H.LPYVEA..AVHYTHRKDYCGN.CS---.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
A0A0B2VN39_TOXCA/20-211              ............................................lpp----ICDHSTRWTVG.ERDIVHESRG..FILLAVFMPLQ...G..SS.NIhTQ.LMKLQAI....-----GETIREVRVVVI............A..........PQ.NEDSRLLD-R.YRAQF.PQ....--V......TFE...MESA.NEPAWA.ALGAS...AYDHFIY..D.....RCGRIAN.VIRH..PR...SdIA...R.FEDTVN..SLKGAINYAHCGW.CNYNL.R..........TA...PT..PALI.A.PE...............MHKRRARETESS....--..-.---...---....-......----..----.-------.....-----------.....------..----------ekcesishllvnelqita................................................................
U6P7T9_HAECO/21-226                  ...........................................rhsl-----CS-TPTLTVR.GVDIVAASKN..TVLVVAFMPLQ...C..AS.CH.RQ.LKRLSYL....ATN-----QNDVRVVVL............A..........--.--PSYEA-PV.TIARV.QA....EFP......RLV...IDRD.THNVWR.LYEAA...NHDQMFF..D.....KCGRVTQ.VIQH..PR...S.DM...TnYRDTLY..AVDSARTQRTCGP.CGNGG.S..........RE...PL..QQHA.S.S-...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------gryeehqrarpsftiranyntrappianngrstytqppqvnnqnygsaq.................................
H0ZC10_TAEGU/1-47                    ...............................................---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...KDDFLVY..D.....RCGRLAF.HIQL..PF...S.FL...H.FPYVEA..AIRSSHIKDFCGN.CSL--.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
A0A0N5CWJ2_THECL/12-184              ..............................................n-TSILCNETKPWKLG.SRDIVADSKG..FVLLVAFMPVE...C..EH.CR.KQ.LMKFQAI....M-----ETVTEVRVIVV............A..........PY.DANPRLI-ER.YREEF.PR....--V......VIG...MESV.NEKIWN.SVSAL...AHDHFIY..D.....RCGRLAN.VIRH..PK...SdTS...K.FEDTMR..ALKSAVNYAQCGW.CQYDP.P..........QL...PT..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------sqrsiipnigtnkmktvv................................................................
H2SF16_TAKRU/1-110                   ...............................................---------------.----------..-----------...-..--.--.--.--RIGGL....RKKLIQSNMTEVSYMIV............N..........EQ.DPHSRALFWE.LERRA.PP....DVP......VYQ...QSAF.QSDVWE.TLDGD...KDDFLIY..D.....RCGQLTF.HVGL..PY...S.FL...N.YVYVEA..AIRATYQGNIC-N.CSV--.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------s.................................................................................
E0CZ76_MOUSE/23-124                  ..............................................g-QSSACYKAPEWYIG.DQNPMLNSEG..KVTVVALLQAS...C..YL.CL.LQ.ASRLEDL....RIKLESQGYFNISYIVV............N..........HQ.GSPSQLKHSH.LKKQV.SE....HIA......VYR...QEED.GIDVW-.-----...-------..-.....-------.----..--...-.--...-.------..-------------.-----.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
A0A067R8W1_ZOONE/3-168               .......................................fvryhmkt---------------.----------..-----------...-..--.--.-Y.IFRMQDL....QVRLISAGFTNIAFRII............N..........SKlAVDGTDGFAT.LKHK-.SG....DIP......VLQ...EPKDiTSSIWQsILDGG...IDHILVL..D.....RCGRLVY.QVIS..PW...S.LL...S.YPYVKA..AILSTYNDDPCGP.CNLLV.T..........EQ...TR..NNTD.T.SM...............EDKTIPRA----....--..-.---...---....-......----..----.-------.....-----------.....------..----------elsssitltkergttianntk.............................................................
Q7Q0I7_ANOGA/166-293                 .........................................lfglre---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...---FQVYviD.....RCSRVSY.IIQP..PW...S.LI...Q.YAYVKA..AVLSTFYDRPCGK.CELEN.F..........LN...ST..LTDG.EkLS...............DVKADPTKDATP....Y-..D.DAS...DEF....S......NPAE..EEED.----HDG....gVRAYSEEEDDD.....DE----..----------sdtdgngrtvdeyka...................................................................
F6V1E8_ORNAN/23-255                  ..............................................s-ASSHCKEAPRWQIR.DQDPMLNSLG..TVTVVALLQASsiiC..IF.FL.LK.PFRLEDL....RVKLENEGYSNISYIIV............N..........HQ.GMPSQLNHKT.LKEKV.SE....HIP......VYQ...QDEK.QTDVWS.TLKGN...KDDFLIY..Dr...sRCGRLVY.HLSL..PY...T.FL...S.FSYVED..SIKTTYCEQNCGN.CSYTM.P..........EA...EE..FCTN.T.SS...............AAKEKATEA-PL....PH..N.DRP...HHH....-......--H-..-HHH.HHHGHKP.....HPSGTEQAPAD.....PDGPLR.sPAPQGLHK--rl................................................................................
U6PFR9_HAECO/21-220                  ...........................................rhsl-----CS-TPTLTVR.GVDIVAASKN..TVLVVAFMPLQ...C..AS.CH.RQ.LKRLSYL....ATN-----QNDVRVVVL............-..........AP.SYEA----PV.TIARV.QT....EFP......RLV...IDRD.THNVWR.LYEAA...NHDQMFF..D.....KCGRVTQ.VIQH..PR...S.DM...TnYRDTLY..AVDSARTQRTCGP.CSNGG.S..........RE...PL..QQHA.S.SG...............RYEEHQ------....--..-.---...---....-......----..----.-------.....-----------.....------..----------rarpsftiranyntrappitnngrstytqspqvnnq..............................................
G3W9K6_SARHA/23-176                  ..............................................n-GTRICQPAPDWQVDgGVSPMEEALG..NVTEVALLKAP...L..TR.P-.FL.APRIGSL....QERLARAGTAGVRFLIV............N..........HK.SAAAQALQGE.LELRA.PR....GVP......VYS...QRGP.RPDIWG.LLGGA...KDDFLVY..D.....RCGRLTF.HIQL..PF...S.AL...S.FPFVEA..AVRFSHQQDHCGN.CS---.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
V4A4R8_LOTGI/1-157                   .............................................ma---------------.----------..-----------...-..--.--.-K.NRKLQTL....KNDLALENKPDVNFFII............N..........G-.-EHSQEL---.IGRFP.SI....EIP......IYQ...-DTE.QLGLWRtVFAGN...KDDFIIF..D.....RCGRRVY.HIPL..PY...S.DL...R.LNYTRY..AIDVVYNRRVCGE.CDSSS.N..........YM...DR..MMGD.Q.P-...............-ASTDVDEHVDI....VG..Q.SDT...---....-......YRHR..RRQR.HGRHQ--.....-----------.....------..----------drdm..............................................................................
W5JI27_ANODA/146-291                 ..........................adernltvypnpltengtfal---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-LGLR...EFQVYVI..D.....RCSRVSY.IIEP..PW...S.LI...Q.FSYVKA..AVLSTFYDRPCGK.CEFEN.Y..........IN...ST..ISDE.D.RN...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------pspgakdatagcinghgpsctemfeesienaeedeggmqdseeddedsysytrtkdesdp......................
G3ID68_CRIGR/21-166                  ........................................cdrpdgp---------------.----------..-----------...-..--.--.--.-NRLEDL....RLKLENQGYSNISYIIV............N..........HQ.GSPSQLKHTH.LKNHV.SD....QIA......VYR...QEEH.QTDVWT.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FPYVEE..AIKIAYCEKKCRN.CSFTL.L..........RV...KR..R---.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------sprrhitttstitntgtgfl..............................................................
G1KY65_ANOCA/23-58                   .............................................gp--STRCKEPPDWRIG.EQNPMLDSRG..FVTVVALLQAS...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...-------..-.....-------.----..--...-.--...-.------..-------------.-----.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
G1LAZ4_AILME/4-242                   ..............................................g-QSSFCKQPPAWSIR.DQSPMLNSGG..SVTVVALLQAS...S..KY.LL.GR.IYRLEDL....RVKLEKEGYLNISYVVV............N..........HQ.GLPSQLKYMH.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGK...KDDFLVY..D.....RCGRLVH.HLGL..PY...S.FL...T.FPYVEE..AIKIAYCEEKCGN.CSLMQ.Ninin..sltqEA...ED..FCKM.V.SS...............ATVGTTTEAPPP....HH..H.HHH...HHH....-......--HR..HHHK.HGHPHHG.....NDELSEDQQPE....aEQAREH..PAPRGLHRHH..................................................................................
W5L435_ASTMX/10-143                  ...........................................ilsl---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...---FLFC..A.....SCGQLTF.HIVL..PY...S.YL...H.HPYVEA..AIRATYHRDIC-N.CTVDS.Ns.......tlSD...EQ..QNST.T.V-...............TTGTSPSQISEEppadPA..R.PVN...GHH....H......HSQT..HGHY.HPTHSHP.....VITKAEDRNIG.....VSHHHT..-HDEGQES--haihkh............................................................................
SEPP1_PONAB/23-249                   ..............................................d-QSSLCKQPPAWSIR.DQGPMLNSNG..SVTVVALLQAS...U..YL.CI.LQ.ASKLEDL....RVKLKKEGYSNISHIVV............N..........HQ.GISSRLKYTH.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGS...KDDFLIY..D.....RCGRLVY.HLGL..PF...S.FL...T.FPYVEE..AVKIAYCEKKCGY.CSLTT.L..........KD...ED..FCKS.V.SL...............ATVDKTVEA---....--..-.PSP...HYH....-......--HE..HHHN.HRHQHLG.....SSELSENQQPG....aPDAPTH..PAPPGLHHHHkh................................................................................
H1A5G2_TAEGU/1-124                   ...............................................---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...KDDFLIY..D.....RCGRLVY.HLGM..PY...S.FL...H.FQYVEE..SIKIAYCENKCGN.CSYME.P..........DA...DG..VCEN.I.TK...............KAVEELSEIEPK....PT..G.QHS...HPNl..hR......HGHH..QRHH.HHHHHHKg...sRDPKHENHQAA.....AEAERH..HPHS------g.................................................................................
E9QB63_DANRE/23-254                  ..............................................t-EGARCKLPPEWKVG.DVEPMKNALG..QVTVVAYLQAS...C..LF.CL.EQ.ASKLNDL....LLKLEKQGYPNIAYMVV............N..........NR.EERSQRLHHL.LQERL.L-....NIT......LYA...QDLS.QPDAWQ.AVNAE...KDDILVY..D.....RCGRLTY.HLSL..PY...T.IL...I.HPHVEE..AIKHTYCDRICGE.CSLES.S..........AQ...LE..ECKK.A.T-...............EEVNKPVEEEPR....QD..H.GHHeqgHHE....H......QGEA..ERHR.HGHHHPHh...hHHHHRGQQQVD.....------..----------vdqqvlsqvdfg......................................................................
SEPP1_RAT/23-248                     ..............................................g-QSPACKQAPPWNIG.DQNPMLNSEG..TVTVVALLQAS...U..YL.CL.LQ.ASRLEDL....RIKLENQGYFNISYIVV............N..........HQ.GSPSQLKHAH.LKKQV.SD....HIA......VYR...QDEH.QTDVWT.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FPYVEE..AIKIAYCEKRCGN.CSFTS.L..........ED...EA..FCKN.V.SS...............ATASKTTEP---....--..-.SEE...HNH....-......--HK..HHDK.HGHEHLG.....SSKPSENQQPG....aLDVETS..LPPSGLHHHHh.................................................................................
A0A0M3JSD2_ANISI/1-103               ...................mvviapynenhrslmrfrnqfpkmhfhi---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...-ESY.NESVSN.KLGAT...ANDHFIY..D....rRCGRLSN.VIRY..PR...SdVT...R.YDDILN..ALKTTINYSHCGW.CIYDT.L..........ST...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------tttpila...........................................................................
G3PMU8_GASAC/1-188                   ...............................................---------------.----------..-----------...-..--.--.--.-------....--------------MIV............N..........ER.EPHSRAMYWE.LKRRA.PP....GVP......VYQ...QAAL.QSDVWE.ALDGD...KDDFLVY..D.....RCGLLTF.HIVL..PY...S.FL...H.NVYVEA..AIRATYLKNIC-N.CTVDS.VvsslnnsvmnN-...--..----.E.TDfnvsqtnatpriqpdTNDPEGAGTPPP....PT..H.HHS...HHH....H......HHHQ..HHHP.HHPHHAH....lNQPLHDTSQNI.....TRHPLS..VHHHHH----phhhh.............................................................................
G3NUN5_GASAC/1-216                   ...............................................---------------.----------..-----------...-..--.--.--.---MDGL....RQKLESQGLKDVAYMVV............N..........QQ.GEQARRLHPM.LAQRL.SV....NID......LYK...QDEQ.QPDVWK.TLGGD...KDDFLVY..D.....RCGRLTH.HIAL..PY...S.II...G.QGHVES..AIKDAYCKRTCGD.CVHES.A..........TT...PE..ECVE.K.AVa............qpDADAPPVVEDNG....GGggH.HGH...HHH....G......HGHH..RGHH.HGHHHGH.....HHGGDHGAGQQavvhqEHERDG..GASHGQH---nsaldqmqqqahipqmphgaqa............................................................
D6REX5_HUMAN/23-249                  ..............................................d-QSSLCKQPPAWSIR.DQDPMLNSNG..SVTVVALLQAS...C..YL.CI.LQ.ASKLEDL....RVKLKKEGYSNISYIVV............N..........HQ.GISSRLKYTH.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGS...KDDFLIY..D.....RCGRLVY.HLGL..PF...S.FL...T.FPYVEE..AIKIAYCEKKCGN.CSLTT.L..........KD...ED..FCKR.V.SL...............ATVDKTVET---....--..-.PSP...HYH....-......--HE..HHHN.HGHQHLG.....SSELSENQQPG....aPNAPTH..PAPPGLHHHHkh................................................................................
A0A0N4U327_DRAME/1-155               ..............................................l-----CTHSTDWSLD.NRNIMHESRG..YILLIAFMPVH...C..NF.CQ.NQ.LKKLQ--....---VTTQIFREIRVVII............V..........AM.DENPRTI-NY.YQQEF.PE....-LT......IIK...-DST.ADRVWE.KHGAT...PHDHFIY..D.....RCGRLSI.IIRH..PR...S.DM...SnYEDTIK..SLKSALNYARCGW.CQYDP.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------qpsfrslpv.........................................................................
A0A0G2JU99_RAT/23-203                ..............................................g-QSPACKQAPPWNIG.DQNPMLNSEG..TVTVVALLQAR...H..FM.CF.L-.-PRLEDL....RIKLENQGYFNISYIVV............N..........HQ.GSPSQLKHAH.LKKQV.SD....HIA......VYR...QDEH.QTDVWT.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FPYVEE..AIKIAYCEKRCGN.CSFTS.L..........ED...EA..FCKN.V.SS...............ATASKTTEPSEE....H-..-.---...---....-......----..----.-------.....-----------.....------..----------n.................................................................................
W5MN82_LEPOC/23-267                  .............................................gg--GGRCKTPPEWAVG.NEQPMTDSAG..RVTVVALLQLN...Y..LVqNL.IF.LNRLDVL....RLRLEQQGLVNISYVVV............N..........HQ.GEQSHRLYPV.LKKKM.SQ....KIR......VYD...QDPL.QEDVWK.ILSGE...KDDFLIY..D.....RCGSLTH.HLGL..PY...S.ML...T.MSYVED..AIRDTYCKDICGN.CSLES.S..........SL...PV..TCNS.T.VKp............egKPEDKPEESPES....HG..H.PHA...HGHg..hHhseegrQSHR..RHSS.HGHHHGH.....GRHHHGSQQEF.....NNGQTQ..RHSQTHQQQ-q.................................................................................
A0A090LRH7_STRRB/44-214              ......................................fqfnrlgam---------------.----------..-----------...-..--.--.--.-------....--------LRDIKFLIL............I..........DK.EFD-QNYLTT.LKNRY.T-....YVS......IIQ...DDGG.QFDPYY.YLNAS...DDEKLLF..D.....RCGRLAMvRKKQ..PIndqS.FM...EeYNILNR..AVNYA----YCGW.CKYDT.S..........KN...QK..NNIN.N.YN...............TYQ---------....--..-.---...---....-......----..----.-------.....-----------.....------..----------qqgrnfikdgsytnvepkntnidsqyaktntkydnfpndvndkkitlnp.................................
F6VJE4_XENTR/25-266                  ..............................................t-NSSICKPPPKWSIE.GEVPMAEALG..KVTVVALLQAS...C..GF.CL.VQ.AARMGPL....RYKLSLQGMTDIKYMIV............N..........DQ.SLHSANMFPE.LKRWA.PE....GIP......VYQ...QTPG.QDDVWE.LLDGN...KDDFLIY..D.....RCGRLTF.HVRL..PL...S.FL...H.FPYVEA..AILSTYNESFCGN.CSFTS.N..........ST...LI.pMNGT.T.VSpsgdd.....sssplQNKDEPVNKEPS....PT..L.EKH...NDQ....R......KLDSelRLHD.HSQHHPI.....-NSHKR-QENQ.....NNHPR-..----------nlikngkqn.........................................................................
W4Z1T3_STRPU/83-177                  .............................................ls---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...-------..-.....-CGQLTY.HIPM..PY...S.AL...R.YPFIQI..AIESTYTGRHPCN.CSADE.P..........TT...TA..MPST.-.-E...............KPHKTPSDRKRS....LR..H.AVS...DNN....N......NN--..----.-------.....-----------.....------..----------yyrksgemqsalidrtdad...............................................................
U3K9A0_FICAL/19-264                  ..............................................t-ESQNCQEPPAWRIG.EEDPMWNSRG..SVTVVALLQCS...E..IL.HI.FKkSGSLEDL....RVKLENEGLVNISYVVV............N..........HQ.GAQSQREFHL.LKERV.SD....YIT......VYQ...QDEQ.QEDVWT.TLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...H.FQYVEE..SIKIAYCENKCGN.CSYTEpD..........ID...ID.vVCEN.I.TK...............KAGDELSEVEPK....LT..G.QHS...HPNp..hR......HGHH..HRRH.HHHHHHKg...gRGPRRENLQAA.....PEPERR..HPHSGRRH--glfghhrh..........................................................................
A0A0K0EXH8_9BILA/65-243              .....................................eifqlnriae---------------.----------..-----------...-..--.--.--.-------....-------TLHDIKFLVL............I..........SK.EFDNRYLNA-.-WSNK.YK....YIS......ILQ...HDGS.QFDPYY.YLNAN...DDDRLLF..D.....RCGRLAM.-VRK..KQ...K.MD...E.TSFLEEfnMLSQSKYHALCGW.CKYDI.S..........KR...LP..ESGE.D.FN...............KYVQKGTNVNTI....RD..G.NFR...ERN....N......NI--..----.-------.....-----------.....------..----------dtnnklnndqiysknykynnsqkvlfdrrisvtq................................................
F1RD74_DANRE/28-263                  ..............................................s-GSRICKPAPQWEID.GKTPMKELLG..NVVVVALLKAS...C..HF.CL.TQ.AARLGDL....RDKLANGGLTNISFMVV............N..........EQ.DSQSRAMYWE.LKRRT.AQ....DIP......VYQ...QSPL.QNDVWE.ILEGD...KDDFLVY..D.....RCGYLTF.HIVL..PF...S.FL...H.YPYIEA..AIRATYHKNMC-N.CSLNA.N..........FS...IS..ESSD.S.TKne..........pagENNQRPNSTEP-....--..-.-VT...AAH....H......HHHQ..QHEP.HHHHNPY.....PNNHKKSGDSD....vTGKPKE..PTHHSHQEH-vhnh..............................................................................
U3JR44_FICAL/27-249                  ...............................................NSSRICHEAPAWTIN.GSSPMEGAAG..QVTVVALLK--...-..-F.CL.RQ.AHSLGGL....RERLARQGTARVRYMIV............N..........EK.APLSRAMLPE.LQRHA.PP....GVP......VLQ...PEQG.DPDVWQ.VLGGD...KDDFLVY..D.....RCGRLAF.HIQL..PF...S.FL...H.FPYVEA..AIRYSHIKDFCGN.CSFYP.I..........TT...QE..SNST.-.--...............--VEVPATPSSF....PE..H.EGM...ESE....T......PIHQ..HKPL.HPHHHHE.....---VSSERNTN.....PSENHK..PATHAHHHH-gdh...............................................................................
V8NYH9_OPHHA/29-180                  ...............................................NQTRICQPAPLWKIN.GTEPMAGMEG..Q----------...-..-F.CL.KQ.AASLGSL....QEKLSGDGMANVSFMIV............N..........EK.TPSSRAMYWE.LKRHA.PK....GVP......VFQ...QQIL.EPEVWQ.ILQGN...KDDFLIY..D.....RCRKLTF.HIQL..PY...S.FL...H.LPYVEA..AVRYTSRKDYCGN.CSWYY.L..........NS...S-..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------qev...............................................................................
G3UU18_MELGA/1-166                   ...............................................---------------.----------..-----------...-..--.--.--.-------....--------------MII............N..........EQ.APLSRAMFGE.LQRHA.PP....GVP......VLQ...QQPH.EPDVWQ.LLGGD...KDDFLVY..D.....RCGRLAF.HIQL..PY...S.FL...H.LPYVES..AIRFTHRKDFCGN.CSLYT.N..........ST...QE..ANST.M.--...............---EVPTTLTPL....PK..Q.EEK...ESE....T......PAHH..QPNHlHPHHHAV.....----GSRTAPE.....PSGDHR..PA-HTHHHH-gahgqlh...........................................................................
U3IXD6_ANAPL/13-195                  ..............................................t-ETQNCQEPPEWRVG.EENPMLNSRG..SVTVVALLQTS...H..NL.SV.LD.HEELEDL....RVKLENEGLVNISYVVV............N..........HQ.GAYSQKKFHL.LKESV.SE....YIT......VYQ...QDEH.QADVWT.TLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...S.FNYVEE..AIKIAYCENKCGN.CSYTE.P..........DI...DA..TCEN.I.TK...............KADEKLAEVEPK....--..-.---...---....-......----..----.-------.....-----------.....------..----------ps................................................................................
A0A0D9RW51_CHLSB/1-190               ...............................................---------------.----------..-----------...-..YL.CI.LQ.ASKLEDL....RVKLEKEGYSNISYIVV............N..........HQ.GISSRLKYTH.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGS...KDDFLIY..D.....RCGRLVY.HLGL..PF...S.FL...T.FSYVEE..AIKIVYCEKKCGN.CSLTT.L..........KD...ED..FCKS.V.SL...............ATVDEAVEA---....--..-.PQP...HYH....-......--HE..HHHN.QGHQHLG.....SSKLSENQQPG....aPDAPTH..PAPPDLHHHHkh................................................................................
W4X313_ATTCE/135-288                 ..................................vnsdflknngtei---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......IFL...QDDP.QSRIWE.RFRAS...REHAVII..D.....RCGKLTY.HVIV..PW...S.IL...F.FPYVKA..AILSTYMDDPCGG.CNPAV.Y..........QA...SN..HENH.V.VEl............tkSTKKDLSTKKDS....SY..R.EID...TKFe.iiW......TTES..LPEN.LTHLHHE.....SSSEEERE---.....------..----------tstassillen.......................................................................
R4GMT5_HUMAN/23-77                   ..............................................d-QSSLCKQPPAWSIR.DQDPMLNSNG..SVTVVALLQAS...C..YL.CI.LQ.ASKLSKM....K----------------............-..........--.----------.-----.--....---......---...----.------.-----...-------..-.....-------.----..--...-.--...-.------..-------------.-----.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------tfvn..............................................................................
W5PG55_SHEEP/23-207                  ..............................................g-QSSYCKQPPAWSIK.DQDPMLNSYG..SVTVVALLQAS...SkhYT.CH.QR.YFRLEDL....RVKLEKEGYSNISYVVV............N..........HQ.EISSRLKYAH.LKNKV.SE....HIP......VYQ...QEED.QPDVWT.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FTYVED..SIKTVYCEDKCGN.CSLKT.Q..........ED...ED..FCKN.V.SL...............ATKEKTAEASQR....H-..-.---...---....-......----..----.-------.....-----------.....------..----------h.................................................................................
V8PHU7_OPHHA/20-55                   ............................................ehq---GRCKEPPEWSIE.EENPMMKSRG..TVTVVALLQAS...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...-------..-.....-------.----..--...-.--...-.------..-------------.-----.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
E2AE76_CAMFO/129-280                 ....................................tnlffedsese---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....--I......IFL...QDDP.QFRIWE.RFRAS...KDQVVVI..D.....RCGQLTY.QIMV..PW...S.IL...Y.FPYVKA..AILSTHQEDPCGG.CDPTM.Y..........QD...PD..YEDY.F.PN...............-SRSTTKGTDQ-....--..-.---...---....-......----..----.-------.....-----------.....------..----------yetdkinaeliwtteqwssgngsvhleeslkeehetnivppvisdkithds...............................
A0A044QQ64_ONCVO/31-263              ...........................................stpi----LCNQTKSWTLD.GQNIVADSKG..FVLLVVLMPMQ...C..EH.CH.KQ.LMKFQTI....MET-----LPEIKIVVV............A..........PY.GANSRLIERY.-R-KE.FS....RIT......I-G...MESL.NERIWN.ILSGS...AHDHFIY..D.....RCGRLAN.LIRH..PK...S.DA...TkSEHTLR..ALKLAVNYAQCGW.CQYNP.An.......llIS...QK..SIDT.T.YAds...........tlNDKTKKTFIKAV....IY..R.QND...KRH....K......VNSD..RQHD.IAPDHER.....-----------.....------..----------fslrtntispmrkeyertsddhsnqkm.......................................................
E0CX80_MOUSE/23-139                  ..............................................g-QSSACYKAPEWYIG.DQNPMLNSEG..KVTVVALLQAS...C..YL.CL.LQ.ASRLEDL....RIKLESQGYFNISYIVV............N..........HQ.GSPSQLKHSH.LKKQV.SE....HIA......VYR...QEED.GIDVWT.LLNGN...KDDFLIY..D.....R------.----..--...-.--...-.------..-------------.-----.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
B0W3C3_CULQU/144-295                 ..........................................aagyn---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....-IS......VYP...NPLN.ENGTYA.MYGLK...EFQVYVL..D.....RCSRIAY.IIEP..PW...S.LI...Q.YSYVKA..AVLSTLYDRPCGE.CDVDN.F..........LN...SS..LPVQ.K.MA...............ELQQMPTAKSTS....TT..T.TTT...TTT...eP......SSSS..TS--.-------.....-----------.....------..----------astprsdvrpyddstesdepmateeyseppeptttee.............................................
E0CY03_MOUSE/33-110                  ..............................................g-QSSACYKAPEWYIG.DQNPMLNSEG..KVTVVALLQAS...C..YL.CL.LQ.ASRLEDL....RIKLESQGYFNISYIVV............N..........HQ.GSPSQLKH--.-----.--....---......---...----.------.-----...-------..-.....-------.----..--...-.--...-.------..-------------.-----.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
A0A085N189_9BILA/40-225              .............................................ep---TTCQPAPPITHN.KNLIMANYAG..YVTLLALIELQ...C..NF.CR.SQ.INSLLKL....SQLFKENYDEPTKFVIV............A..........PL.NESSMFVHYY.REYLL.PY....RFD......VI-...QETA.AELIWS.PLGGG...KFDFFVY..D.....RCGRLNY.YIPY..PQ...S.FM...Y.YHYTIS..SLHSTHRHQRCGP.CPIHL.I..........SE...KA..ELDQ.T.EL...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------nlaesdhykpknvkawley...............................................................
M4A9J5_XIPMA/5-210                   .......................................vqasrltq---------------.----------..---ITALIQTD...D.kRI.SK.NY.WNNIGRL....RTKLRRSNVTDVSFLIV............N..........EQ.NAVSRALYWE.LKKRA.PT....GVP......VYQ...QDAN.QTDVWE.VLDGD...KDDFLIY..D.....RCGLLTF.HVVL..PY...S.FM...H.NPYVEA..AIRATYVGDIC-N.CSAIS.T..........RT...PD..TVQP.P.D-...............EGVDPTEKTQPI....PH..H.YHH...LSS....-......--FF..HHQP.APRNKTQ.....-DQDRPVIFPA.....PYHPHH..AHQH------phhk..............................................................................
Q16FG7_AEDAE/94-251                  .......................................ynkinyde---------------.----------..-----------...-..--.--.-Q.IQLFHNL....FNRFEHNGYRNVQFILG............Aap......srHP.DETEFTEFEDfLDNVT.SVaagyNIS......VYP...NPLN.ENGTFA.MFGLK...EFQVYVV..D.....RCSRISY.IIEP..PW...S.LI...Q.YSYVKA..AVLSTMYDRPCGE.CDVDN.F..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------lnaslpekkldqfimlpalnvteta.........................................................
M3XHZ2_LATCH/1-183                   ..............................................m---------------.----------..-----------...-..--.--.-Q.AARLGSL....HEKFARKGMEDIRYLIV............N..........NK.SPSSRAMFWE.LKRHA.PA....NIT......VYQ...QAPL.QKNVWQ.ILEGK...KDDFFIY..D.....RCGKLTF.QISL..PF...S.FL...N.NSYVEA..AIMSTYHSDKCGN.CSAANfN..........QT...VQ..VGSN.T.SV..............sAWEESGKEGLGQ....N-..-.---...---....-......----..----.-------.....-----------.....------..----------kqsvedyiqhplarldplpslpppphrhlhkrhqrfpeae..........................................
SEPP1_MOUSE/23-268                   ..............................................g-QSSACYKAPEWYIG.DQNPMLNSEG..KVTVVALLQAS...U..YL.CL.LQ.ASRLEDL....RIKLESQGYFNISYIVV............N..........HQ.GSPSQLKHSH.LKKQV.SE....HIA......VYR...QEED.GIDVWT.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FPYVEE..AIKIAYCEERCGN.CNLTS.L..........ED...ED..FCKT.V.TS...............ATANKTAEP---....--..-.SEA...HSH....-......--HK..HHNK.HGQEHLG.....SSKPSENQQPG.....PSETTL..PP-SGLHHHHrhrgqhrqghlesudttaseglh...........................................................
F4X476_ACREC/178-323                 ...................................vnsdflknnete---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....--I......IFL...QDDP.QSRIWE.RFRAS...REHAVII..D.....RCGMLTY.HVIV..PW...S.IL...F.FPYVKA..AILSTYMDDPCGE.CNPAV.Y..........RA...SN..HEDH.V.VE...............LTKSTKKELNPS....YR..E.VDT...KFEi..iW......TTES..LPEN.LTHLHYE.....-----------.....------..----------ssseeeretsiassi...................................................................
A6GDZ9_9DELT/130-246                 ..........................................fqpqs-----------CNFG.ETTSLEAYKG..RVTLVTLMRTT...C..EI.CQ.GT.IEKLEEM....RLELELDGY-DVYFLAI............N..........QM.GYESTQQ--E.FIDRV.AF....--P......L-L...QDTA.EVDAWE.LLNDTglgTDDIYIY..G.....ADGSL--.----..--...-.--...-.------..-------------.-----.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------rsyfn.............................................................................
A0A087XRM9_POEFO/1-178               ...............................................-----CQPPSTWMIG.EVEPMKGTAG..QVTVVALLKEI...L.gEH.PL.TQ.AARIDGL....RQKLETQGLNDVVYMVI............N..........HQ.GEQAQRLHPM.LAERL.SD....KIS......LYK...QGEQ.QPDVWQ.ALNGK...KDDFIIY..DslcnlRCGRLTH.HISL..PY...S.VI...G.HGHIES..AIKEAYCNRMCGA.CSHES.Q..........TA...ETseGCRA.T.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------pnaqpead..........................................................................
J0XLE8_LOALO/31-255                  ...........................................stpi----LCSQTKPWKLS.GRDIVSDSKG..LVLLVVLMPME...C..EH.CH.KQ.LMKFQTV....MET-----LPEIRIVVV............A..........PH.DENPRLIERY.-REEF.P-....RVA......I-G...MESL.DERIWN.TLSGS...AHDHFIY..D.....RCGRLAS.IIRH..PE...SdTS...K.FEHTLW..ALKLAISYAQCGW.CQYDP.P..........DL...PS..PHKP.L.VT...............THASSTH-----....--..-.---...---....-......----..----.-------.....-----------.....------..----------kgktkrprikavmypqngrtrmvssdrqadfapdherfssrtntvsparkgharis..........................
M3YSM4_MUSPF/1-167                   ..............................................m---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.---------N.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGK...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FPYVEE..AIKIAYCEEKCGN.CSLTT.L..........EA...KD..FCEM.V.SS...............PTVGNTTEAPQP....HH..H.HHH...HHH....H......LHHH..HHHK.HGHQHHG.....NKELSESQRPE....aPDAAEY..PAPEGLHQHHkhkthqrqghp.......................................................................
A0A084VVU1_ANOSI/272-443             rvpyevveynftdffrsvqtlasehnftvypnhltenrtfalfglre---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...---FQVYviD.....RCLRVSY.IIQP..PW...S.LL...Q.YAYVKA..AVLSTFYDRPCGK.CELEN.F..........LN...ST..VLDD.E.KD...............HGKLASITSWAK....PY..E.ETS...EEY....T......TTGE..DENE.AEGSFSD.....EEDNEN-----.....------..----------dsnrerttgttkddsdpfanlt............................................................
F7EK34_ORNAN/12-166                  ..............................................n-GTRICQPAPRWTVN.GVAPMEGTEG..QVIVVALLKAR...S..FF.CA.LP.SAYLAGL....RERLAGHGAGNVSFLIV............N..........QR.DPTAQLLHTE.LERHA.PP....GVP......VYA...QDGP.DPDVWS.VLGGD...KDDFFVY..D.....RCGRLTF.HIQL..PF...S.FL...H.FPYVEA..AVRFTHRRDFCGN.CSY--.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
A0A085N189_9BILA/333-475             ............................lsllklsqlfkenydeptk---------------.----------..-----------...-..--.--.--.-------....-------------FVIV............A..........PL.NESSMFVHYY.REYLL.PY....RFD......VI-...QETA.AELIWS.PLGGG...KFDFFVY..D.....RCGRLNY.YIPY..PQ...S.FM...Y.YHYTIS..SLHSTHRHQRCGP.CPIHL.I..........SE...KA..ELDQ.T.EL...............N-----------....--..-.---...---....-......----..----.-------.....-----------.....------..----------laesdhykpknvkawley................................................................
J9NST4_CANLF/1-138                   ..............................................m---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.---------Y.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGK...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FPYVEE..AIKRAYCEEKCGN.CSLTV.L..........ED...EE..VCKM.V.SS...............GTVESTTEAPQP....HP..H.DHH...LH-....-......---H..HHHH.HHHKHHD.....-----------.....------..----------kftstyqafkalkch...................................................................
R4GJB1_CHICK/1-203                   ...............................................---------------.----------..-----------...-..HF.CL.LQ.ARSLGAL....RERLGQQGVSDVRYVIV............N..........EQ.APLSRAMFGE.LQRHA.PP....GVP......VLQ...QQPH.EPDVWQ.LLGGD...KDDFLVY..D.....RCGRLAF.HIQL..PY...S.FL...H.LPYVES..AIRFTHRKDFCGN.CSLYP.N..........ST...QE..ANST.M.E-...............----VPATLTPL....PK..Q.EEK...ESE....T......PAHH..-QPN.HLHPHHR.....--AVGNGTAPE.....PSGDHR..PA-HAHHHH-gahgklhpkgqtpegrd.................................................................
G3TLW1_LOXAF/23-207                  ..............................................v-QSSFCKQPPAWKIR.EEDPMLNSIG..SVTVVALLQAS...RknYT.CL.QR.TCQLEDL....RVKLEKEGYSNVSYVIV............N..........HQ.DLNSRLKYIH.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FPYVEA..AIKIVYCEEKCGN.CSLMT.P..........ED...ED..FCKK.V.SS...............VNVEDTAEASKP....H-..-.---...---....-......----..----.-------.....-----------.....------..----------h.................................................................................
SEPP1_BOVIN/23-290                   ..............................................g-QSSYCKQPPPWSIK.DQDPMLNSYG..SVTVVALLQAS...U..YL.CI.LQ.ASRLEDL....RVKLEKEGYSNISYVVV............N..........HQ.GISSRLKYVH.LKNKV.SE....HIP......VYQ...QEEN.QPDVWT.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FTYVED..SIKTVYCEDKCGN.CSLKA.L..........ED...ED..VCKN.V.FL...............ATKEKTAEASQR....HH..H.PHP...HSHp..hP......HPHP..HPHP.HPHPHHGhqlheNAHLSESPKPD....tPDTPEN..PPPSGLHHHHhrhkgpqrqghsdncdtpvgseslqps.......................................................
A7RTX8_NEMVE/23-190                  .............................................es--AGVCQRPRPWTVN.GMDPMAQARAdkQIVVLALMEAR..aC..GI.CV.RQ.AKAMESLltmlRQRERSYQLGNLSFMIV............N..........HH.MAAGSIRF--.IEGRV.S-....-FP......VYQ...-ENA.NKQIWP.AVDGA...KDDIIVY..D.....RCGGLVS.HLKW..PK...S.DL...T.KPHLWQ..AIQRAKWSKAC--.CKQQT.T..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------epptisdggk........................................................................
F4X476_ACREC/858-966                 ............................................itl---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...-------..-.....-CGMLTY.HVIV..PW...S.IL...F.FPYVKA..AILSTYMDDPCGE.CNPAV.Y..........RA...SN..HEDH.V.VE...............LTKSTKKELNPS....YR..E.VDT...KFEi..iW......TTES..LPEN.LTHLHYE.....-----------.....------..----------ssseeeretsiassi...................................................................
A6FZW7_9DELT/137-264                 .....................cpecapiwdlydfqpqscgytetygl---------------.-----DSFEG..HVTLIAMLAGW...C..SY.CQ.SQ.AGKMEEM....RLELALEGY-DVQMIAI............N..........AT.SADNDDDRQN.LVDRC.A-....-FP......LF-...QDID.EVDAWD.LHGGT...KDDLVIY..H.....ADGTMA-.----..--...-.--...-.------..-------------.-----.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------vfld..............................................................................
H2UNP3_TAKRU/23-253                  ..............................................g-DGPRCQLPPVWKIG.DLEPMKEAMG..RVTVVALLESS...W..LS.DF.LH.LGRMDSL....RQRLENQGLRDVVYMVV............S..........HQ.GAHAPGLHAM.LAQKL.TE....HIS......LYK...QDEA.LPDVWQ.TLGGN...NNDFFIY..D.....RCGRLTH.RISL..PY...S.II...G.HGHVER..AVKDTYCNSLCGE.CTHET.T..........ET...LQ..ECTP.K.TS...............ALPDNGVAPGAE....E-..-.TGH...ECH....H......HGRQ..HHGD.GHRDHGD.....-SQCTHTRGSG.....RGHGHH..HGHGGQGQH-eg................................................................................
A0A077ZBY8_TRITR/1-193               ............................................mep---TTCQPAPPITHN.SNLIMANYAG..YVTLIALIELQ...C..NF.CR.SQ.INSLLKL....SQLFKENYDEPTKFVIV............A..........PL.NESSMFVHYY.REYLL.PY....KFD......VI-...QETA.AELIWN.PLGGG...KFDFFVY..D.....RCGRLNY.YIPY..PQ...S.FM...Y.YHYTIS..SLHSTHRHQRCGP.CPIHL.I..........SE...KG..NNK-.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------vaeqtfansvifkvelgqadlnlagsdhy.....................................................
H3DGX7_TETNG/23-251                  ..............................................g-DGPRCQLPPTWKIG.DLEPMTGAMG..RVTVVALLDAR...S..TI.DF.LN.LGRMDSL....RQKLENQGLRDVVYMVV............N..........HQ.GAQARGLHAM.LAQRL.SE....HIS......LHR...QDEA.LADVWQ.TLGGN...KDDFFIY..D.....RCGRLTH.RISL..PY...A.VI...G.HGHVEK..AVKDTYCSSLCGE.CTHET.A..........ET...QQ..ECTP.K.T-...............--DTQPQED---....TR..H.ECH...HRH....H......QGHQ..HHGD.GHRDHGD.....-NQCTHTQGSG.....PGHDHG..HGHHGGQGHHqgh...............................................................................
F6PUF8_HORSE/23-250                  ..............................................g-QSSFCKQPPAWSIR.DQDPMLNSYG..SVTVVALLQAS...C..YL.CL.LQ.ASRLEDL....RVKLEKEGYSNISYVVV............N..........HQ.EISARLKYIH.LKNKV.SE....YIA......VYQ...QEEN.QTDIWT.LLNGS...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FPYVEE..AIKIAYCEKKCGN.CSLMT.L..........ED...ED..FCKT.L.SL...............ATVEKTTED---....-S..Q.PHH...HHH....-......--HQ..HHHK.HGHQHVG.....NSQLSENQQPE....aTGAPEH..PPPPGLHHHHk.................................................................................
G5APA7_HETGA/37-233                  .................................plvklneiihlmhf---------------.----------..-----------...-..--.-F.PK.YLRFEDL....RVKLEKEGYSNISFVIV............N..........HQ.GSNSRLKYIQ.LKNQV.SD....HIP......VYQ...QEEH.QTDVWS.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...S.FPYVEE..AIKIAYCEEKCGN.CSLRT.L..........ED...ED..FCKN.V.SL...............ATVEKTAEA---....--..-.--P...HPH....-......--NK..QHHK.HGHQHLG.....GSELSDNKQPE....aPDNPVL..S-PLGHHHHHe.................................................................................
J9FD25_WUCBA/10-174                  ....eqlmkfqtvmetlseirivviapydenprlieryrkefsrvti---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......--G...MESL.DERIWD.TLSGS...GHDHFIY..D.....RCGRLAS.VIRH..PK...S.DT...SkSEHTLR..ALKSAISYAQCGW.CQYDP.P..........DL...PQ..EPVI.T.TY...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------asltrkgktrrpmavvekeadtleqfssnwflegaqfenrrnqs......................................
M4ANC2_XIPMA/23-205                  ..............................................g-GGPRCQPPPTWMIG.EVEPMKGTAG..QVTVVALLQAT...L..RL.QI.LS.NQRIDGL....RQKLETQGLNDVVYMVI............N..........HQ.GEQAQRLHPL.LAQRL.SD....KIS......LYK...QGEQ.QPDVWQ.TLNGK...KDDFIIY..Ds...lRCGRLTD.HISL..PY...S.VI...G.HGHIES..AIKEAYCNRKCGA.CSHET.A..........ET...PE..ECRA.T.PN...............AQ----------....--..-.---...---....-......----..----.-------.....-----------.....------..----------pdadtpaavg........................................................................
F1N9T1_CHICK/1-159                   ...............................................---------------.----------..-----------...-..-L.CL.LQ.ASRLEDL....RVKLENEGLVNISYVVV............N..........HQ.SPHSQKKFHL.LQESV.SD....HIT......VYQ...QDDH.QADVWT.TLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...S.FQYVEE..AIKIAYCENNCGN.CSYTE.P..........DI...DN..ICEN.I.TK...............K---EGIEPEPE....PS..G.QHS...HHH....H......QLHR..HRHH.H------.....-----------.....------..----------..................................................................................
A0A0R4IUA1_DANRE/28-262              ..............................................s-GSRICKPAPQWEID.GKTPMKELLG..NVVVVALLKA-...S..HF.CL.TQ.AARLGDL....RDKLANGGLTNISFMVV............N..........EQ.DSQSRAMYWE.LKRRT.AQ....DIP......VYQ...QSPL.QNDVWE.ILEGD...KDDFLVY..D.....RCGYLTF.HIVL..PF...S.FL...H.YPYIEA..AIRATYHKNMC-N.CSLNA.N..........FS...IS..ESSD.S.TKne..........pagENNQRPNSTEP-....--..-.-VT...AAH....H......HHHQ..QHEP.HHHHNPY.....PNNHKKSGDSD....vTGKPKE..PTHHSHQEH-vhnh..............................................................................
H3DJR4_TETNG/1-201                   ...............................................---------------.----MEALVG..RVVVVALLKAS...T..PP.CD.AP.FPRIGPL....REKLSRRNVTEVSFVIV............N..........EQ.EPVSRALYWQ.LRRRA.PP....GVP......VYQ...QAPL.QDDVWE.ALDGD...KDDFLIY..D.....RCGQLTF.HIGL..PY...S.SL...R.YTYVEA..AVIATYQGNIC-N.CSANC.H..........IS...EH..QQQQ.R.K-...............-WRDAQSDQPDG....HC..G.DRW...STH...yP......PPPS..PSPP.ATHTHTD.....-----------.....------..----------arpshthtsldlpppp..................................................................
E0CZC5_MOUSE/23-177                  ..............................................g-QSSACYKAPEWYIG.DQNPMLNSEG..KVTVVALLQAS...C..YL.CL.LQ.ASRLEDL....RIKLESQGYFNISYIVV............N..........HQ.GSPSQLKHSH.LKKQV.SE....HIA......VYR...QEED.GIDVWT.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FPYVEE..AIKIAYCEERCGN.CNL--.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
H3CE96_TETNG/6-134                   .....lfmvylrsgmwslliyciywhlklglsdevdnceslhlgqyl---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...-------..-.....-------.----..--...-.--...-.------..----------CNE.PRIDEaT..........QE...PE..NCKD.M.IA...............WGETRSRSKNQK....TH..EdTHT...HTH....T......HTHT..HTHT.HTHTHTH....tHQPVNLQLHTSt...nSQAKQH..----------palgyrcr..........................................................................
H2PXQ5_PONAB/1-188                   ...............................................---------------.----------..-----------...-..YL.CI.LQ.ASKLEDL....RVKLKKEGYSNISYIVV............N..........HQ.GISSRLKYTH.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGS...KDDFLIY..D.....RCGRLVY.HLGL..PF...S.FL...T.FPYVEE..AIKIAYCEKKCGN.CSLTT.L..........KD...ED..FCKS.V.SL...............ATVDKTVEA---....--..-.PSP...HYH....-......--HE..HHHN.HGHQHLG.....SSELSENQQPG....aPDAPTH..PAPPGLHHHH..................................................................................
A0A0N4WS67_HAEPC/21-240              ........................................rhslcst---------PTLTVR.GVDIVAASKN..TVLVVGFMPLQ...C..AS.CH.RQ.LKRLSYM....ATN-----QNDVRVVVL............A..........--.--PSYE-APV.TISRV.QA....EFP......RLV...IDRD.THNVWR.LYEAA...NHDQMFF..D.....KCGRVTQ.VIQH..PR...S.DM...TnYRDTLY..AVDSARTQRTCGP.CSNGG.S..........RE...PL..TSHK.T.IT...............VKSANVQQQHAS....SG..R.YEE...HQ-....-......----..----.-------.....-----------.....------..----------rarpsftiranyntrappitnngrstytqppqvnnqnyggaq........................................
G1Q9G6_MYOLU/23-202                  ..............................................g-QSPFCKPPPAWITL.VYVFIRYPH-..--STASLLKKT...Y..YF.CL.RQ.ASSLEDL....RVKLEKEGFSNISYVVV............N..........HQ.GHPSRLRYNL.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PF...S.IL...E.FPYVEQ..AIKIAYCEEKCGN.CSLTT.L..........ED...ED..FCKN.M.SL...............ATVRKTTEASEP....H-..-.---...---....-......----..----.-------.....-----------.....------..----------h.................................................................................
F6Q9N1_XENTR/23-205                  ............................................ghr---KRCKEPPEWSIG.DQNPMMQSAG..KVTVVALLQAS...R..HQ.CL.G-.-FRLEDL....RLKLEKEKLVGISYVVV............N..........HQ.GRQSRAKYDL.LKSKV.SE....HIP......VYQ...QEEY.QPDVWS.LLKGD...KDDFFVY..D.....RCGRLVQ.HLEL..PY...S.LL...H.FPYVEE..AIRIAYCEDKCGE.CEHKK.P..........EE...QQ..EQDK.P.VE...............EKVERPRHHRNH....H-..-.---...RH-....-......----..----.-------.....-----------.....------..----------h.................................................................................
A0A0K0JE39_BRUMA/7-208               ...........................................stpi----LCSQTKSWKLG.GRDIIADSKG..FVLLVALMPME...C..EH.CH.EQ.LMKFQTV....MET-----LPEIRIVVI............T..........PY.DENPRLIERY.RKEFS.RV....AIG......I--...-ESL.DERIWD.TLSGS...GHDHFIY..D.....RCGRLAS.VIRH..PK...SdTS...K.FEHTLR..ALKSAISYAQCGW.CQYDP.P..........DL...PQ..EPVI.T.T-...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------yasftrkgktrrprikavvypqngradtlssdhrstldqer.........................................
I3JR88_ORENI/1-180                   ...............................................---------------.----------..-----------...-..--.--.--.-------....--------------IIV............N..........ER.DAHSRAMYWE.LKRSA.PT....GVP......VFQ...QQPF.QNDVWE.ALDGD...KDDFLVY..D.....RCGLLTF.HIVM..PY...S.FL...H.HPFVEA..AIRATYQKNIC-N.CTQNF.T..........SSvggNN..ITNN.G.TA...............QLVDEGSEVPDT....AS..G.RTH...HHH....H......HHHH..HDDP.PSHHHHH.....-DQHSSHQNQS.....LHQQDQ..GDSTSHHHHHsphqqhqhdh........................................................................
D6RIS9_HUMAN/23-209                  ..............................................d-QSSLCKQPPAWSIR.DQDPMLNSNG..SVTVVALLQAS...C..YL.CI.LQ.ASKLEDL....RVKLKKEGYSNISYIVV............N..........HQ.GISSRLKYTH.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGS...KDDFLIY..D.....RCGRLVY.HLGL..PF...S.FL...T.FPYVEE..AIKIAYCEKKCGN.CSLTT.L..........KD...ED..FCKR.V.SL...............ATVDKTVETPSP....HY..H.HE-...---....-......----..----.-------.....-----------.....------..----------h.................................................................................
W5KEM0_ASTMX/23-259                  ..............................................g-DGARCKPPAVWKIG.DVEPLKDSLG..QVTVVAFLQKT...K.wVL.DD.LT.LDRLDSL....RLKLEKAGYANITYLVV............N..........SQ.DENSRRLHSL.LEQRL.SA....NIT......LYG...QEPD.AQDIWQ.IANVM...KDDFQIY..D.....RCGRLTH.HLSL..PY...T.IL...S.GPHVEE..AIRNTYCDRTCGE.CSMES.S..........IQ...PQ..ECNG.T.V-...............--EEKPVVEEEE....VG..R.GHHg.gGHHs..gH......HGGH..HGGH.HGGHHGG.....HHGGHHSGHHG.....HHGDHG..GQQRGHHDQHtd................................................................................
A0A088AAX3_APIME/26-230              .......................................qcratnlr---------------.-----KDQLG..HVNVFAFLDPS...W..NY.SY.RQ.AVMLELL....KKQLEKSGFSNILLFMVarpsdlpeddteNsmeikawleiSK.NIQESEHFLS.LDKMI.FS....DIAkekkgiIFL...QDTF.ELGIWK.SFRAS...KDEVIII..D.....RCGKITY.QIIV..PW...S.IL...Y.FPYVKA..AILSTYKDDPCGP.CYEQS.S..........II...RE..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------sidyrdyllktinsekkkinknldirp.......................................................
A0A0P7ZE00_9TELE/1-115               ...............................................---------------.----------..-----------...-..--.--.--.---MDDL....RQKLEQQGFDNITYMVV............N..........SQ.ELVARLFHHH.LRQKM.SE....NIT......LYV...QDPK.QDDIWQ.ILSGD...KDDFLVY..D.....RCGLLTY.QISM..PF...S.KL...S.MPYVEN..AIRKTYCKNICAN.CLLE-.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------viais.............................................................................
A0A096MFI7_POEFO/5-209               ....................vqasrltqitsliktdgerifhngsfl---------------.----------..-----------...-..--.--.--.-LNIGRL....RTKLRRSNITDVSFVIV............N..........EQ.DAASRALYWE.LKKRA.PT....GVP......VYQ...QAAN.QTDVWE.VLDGD...KDDFLIY..D.....RCGLLTF.HVVL..PY...S.SL...Q.NPYVEA..AIRATYLGDIC-N.CSAIS.T..........RT...PS..IQGT.I.Q-...............TPDEGADPTEET....QT..I.PHH...YHH....H......FSFS..HHQP.APRDKSQ.....D-QHRS-----.....------..----------aifpapyhphhah.....................................................................
C3YH40_BRAFL/68-195                  ............................................ggl---------------.----------..-----------...-..--.--.--.-------....-QKLYSEGKSDIFFGAV............N..........HW.GWASWWYRGE.LERRA.--....NFP......VYQ...-DSW.SQDIWG.KLHAA...KDDILVY..D.....RCGRLAY.HLRL..PR...A.YL...G.NTHTEE..AIRAAYRQSPCGP.CGTLA.G..........ET...AT..PCF-.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------trlsvirlkisqlh....................................................................
A0A0P7UJP5_9TELE/61-206              .............................................dp--SKICEPPPQWEID.GRAPMQEHLG..NVVVAA-----...-..--.--.--.--NMGVL....RNKLLRYGLRNVSYLIV............N..........QQ.DISSRRQYQE.LKRRA.PK....EIP......VYQ...QAPR.QQNVWK.LLNGA...KDDFLIY..D.....RCGRLTF.HIVL..PY...T.FL...Q.YPYVEA..AIWVSYRKDICGN.CSVSD.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------aah...............................................................................
A0A093BFN6_CHAPE/1-116               ...............................................---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.FL...T.FQYVED..SIKVAYCENKCGN.CSYME.P..........DI...DD..ICEN.I.TK...............KADEKLAELEPS....PT..G.QHS...HQQ...nW......NRHR..HHHG.KGSHHSK.....T------ENHQ....aPSGAHR..HP--------hsg...............................................................................
SEPP1_HUMAN/23-249                   ..............................................d-QSSLCKQPPAWSIR.DQDPMLNSNG..SVTVVALLQAS...U..YL.CI.LQ.ASKLEDL....RVKLKKEGYSNISYIVV............N..........HQ.GISSRLKYTH.LKNKV.SE....HIP......VYQ...QEEN.QTDVWT.LLNGS...KDDFLIY..D.....RCGRLVY.HLGL..PF...S.FL...T.FPYVEE..AIKIAYCEKKCGN.CSLTT.L..........KD...ED..FCKR.V.SL...............ATVDKTVET---....--..-.PSP...HYH....-......--HE..HHHN.HGHQHLG.....SSELSENQQPG....aPNAPTH..PAPPGLHHHHkh................................................................................
H0UZB3_CAVPO/1-141                   ...............................................---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.SD....HIS......VYQ...QEQH.QPDIWS.RLKGN...KDDILIY..D.....RCGRLAY.HLRM..PY...S.FL...S.FPYVEQ..AIKIVYCVEKCGN.CSLKN.L..........ED...DD..FCKN.V.SL...............AA--VTTEAPQK....HH..H.RQI...HPP....K......RGHP..----.-------.....-----------.....------..----------ylgsrepeapdnpvqslplglhnlhrgqprqvh.................................................
E5SI43_TRISP/46-261                  ............................................dep---DICHPVPMFTNG.GQLVMTNYHG..HVTLIALMELQ...C..TL.CR.TQ.ISSIVKL....SELFRENYDEPTKFLVV............A..........PH.NESDRFV-EY.YKQYLkPY....DIG......VI-...QETT.AEPIWH.TLRGS...RFDFFVY..D.....RCGRLNY.YIPY..PQ...S.FM...Y.YHYTIS..SLHSTHRYIKCGP.CPSNR.Q..........DI...ST..AAVS.V.GKt.............lTDDGQWNSNDQR....ST..F.PSE...---....-......----..----.-------.....-----------.....------..----------tssvykhhlpkyqpkyirglsgdptgen......................................................
I3LJP2_PIG/5-135                     ............................................yyy---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......---...----.------.-----...-----YY..F.....RCGLLVY.HLGL..PY...S.FL...T.FPYVEE..AIKTVYCENKCGN.CSLKT.L..........KD...ED..FCKN.V.YL...............ATEEKTTEAPQP....HH..H.HDH...HHH....-......--RH..HHHH.HGHQHLG.....NGHLSEHPKPE....aPDTPEQ..PPPSGLHHHHghkghqrqgh........................................................................
A0A096M0U7_POEFO/1-106               ..............................................l---------------.----------..-----------...-..-F.CL.VQ.ASRIDGL....RQKLETQGLNDVVYMVI............N..........HQ.GEQAQRLHPM.LAERL.SD....KIS......LYK...QGEQ.QPDVWQ.ALNGK...KDDFIIY..DslcnlRCGRLTH.HISL..PY...S.VI...G.HGHIE-..-------------.-----.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
B7Q2F3_IXOSC/1-206                   ..............................................m---------------.----------..-----------...-..--.--.FQ.IISLEAL....LLKLRARNLSDVQFLVV............N..........SL.D--SAAEVRQ.LERRV.S-....-FP......VYQ...-ETA.DEPVWS.VLEGD...KDDVFIY..D.....RCGRLSY.FIPF..PL...S.VMlpgR.HPVVEE..ALNTTYYASPCGDfCPQDP.S..........AT...PH..RSS-.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------phehqqripgeiavqdggepgttvsppttpseglgwrvihmvfgdghqgqvdshtpshareggvttgaphdhqerqptpmec
A0A0J7NEP2_LASNI/96-254              .....................................dlvnadellf---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.---KD.SE....QEM......IFL...QDDP.QLRMWE.KFRAS...KDQVVVI..D.....RCGKLTY.QVMV..PW...S.IL...Y.FPYVKA..AILSTYQEDPCGG.CDPIM.Y..........QA...LD..YEEY.F.PSsrs.........ttaKETDPPRETD--....--..-.---...---....-......----..----.-------.....-----------.....------..----------dnvdagpmwtterwssrnvsahleespstvspvisdkmtydsdddpp...................................
H2MB78_ORYLA/1-159                   ...............................................---------------.----------..-----------...-..--.--.--.-------....--------------MIV............N..........EL.EALSQTMHWK.LKKKA.PT....GVP......VYQ...QSSL.QKDVWE.ILDGD...KDDFLIY..D.....RCGLLTF.HIVL..PN...S.FL...Q.NADVEN..AITATYTQDIC-N.CSGNS.TlsgggnnftrN-...SS..----.-.-Qshsgvq...rpadepENVTTTLEASPN....DS..R.HEH...AHH....H......HPHH..QHLH.HHHPHHQ.....-----------.....------..----------hlh...............................................................................
SELPA_DANRE/23-255                   ..............................................t-EGARCKLPPEWKVG.DVEPMKNALG..QVTVVAYLQAS...U..LF.CL.EQ.ASKLNDL....LLKLENQGYPNIAYMVV............N..........NR.EERSQRLHHL.LQERL.L-....NIT......LYA...QDLS.QPDAWQ.AVNAE...KDDILVY..D.....RCGRLTY.HLSL..PY...T.IL...S.HPHVEE..AIKHTYCDRICGE.CSLES.S..........AQ...LE..ECKK.A.T-...............EEVNKPVEEEPR....QD..H.GHH..eHGHh..eH......QGEA..ERHR.HGHHHPHh...hHHHHRGQQQVD.....------..----------vdqqvlsqvdfgq.....................................................................
K7E6A4_MONDO/1-186                   ...............................................---------------.----------..-----------...-..--.--.--.---MGSL....QERLARMGAPDVRFIIV............N..........EK.SPQSRALHGE.LELHA.PP....GVP......VYG...QPEL.GPDIWS.ILGGA...KDDFLIY..D.....RCGRLTF.HIRL..PF...S.FL...H.FPYVES..AIRFTHRQDSCGN.CSFYP.A..........QV...NS..TDER.K.GEskhs.......pgleG-----------....--..-.---...---....-......----..----.-------.....-----------.....------..----------egqeplgekpdsrgltlgssaptahahdpvhggmekpspslpspalepslhege............................
K7JYM3_NASVI/162-308                 .........................................lgpdvy---------------.----------..-----------...-..--.--.--.-------....-----------------............-..........--.----------.-----.--....---......-FI...QDND.ELQIWS.KLRAF...RDQILVI..D.....RCGRLTY.QVIV..PW...S.IL...H.FPYVKA..AILSTYKDEPCGY.CQFKE.T..........VF...DT..TSTDnK.DA...............QSSSKLVEQTED....ND..N.P--...---....-......----..----.-------.....-----------.....------..----------stlsqetttviyeaesydttltvdessspivqtehevtslstsdrn....................................
W5M4W3_LEPOC/1-173                   ..............................................m---------------.----------..-----------...-..--.--.--.-------....---------TDVGFLIV............N..........ER.EPVSRAMFWE.LKRRA.PE....GIP......VYQ...QGLF.QSDVWE.ILEGE...KDDFLIY..D.....RCGLLTF.HIVL..PY...S.FL...H.YPYVEA..AIRATYLRDICGN.CTLDS.S..........DN...QG..LNAS.Q.IP...............ERKENVTDAECL....DD..H.EQH...QGE....Q......SNGP..QPSR.HSQAHHS.....GHRLVHGPCRD.....KGRKRP..P---------spqnstl...........................................................................
A0A0N5DGW6_TRIMR/275-459             ............................................mep---TTCQPAPPITHN.GNLIMANYAG..YVTLLALIELQ...C..NF.CK.SQ.ISSLLKL....SQLFKENYDGPTKFVIV............A..........PL.NESAMFVHYY.REYLL.PY....GFD......VI-...QETA.TEPIWG.PLSGG...KFDFFVY..D.....RCGRLSY.YIPY..PQ...S.FM...Y.YHYTIS..SLHSTHRHQRCGP.CPIHL.V..........SE...KE..L---.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------dqaelslarpdhykpknvkawve...........................................................
W5MN70_LEPOC/1-198                   ...............................................---------------.----------..-----------...-..--.--.--.---LDVL....RLRLEQQGLVNISYVVV............N..........HQ.GEQSHRLYPV.LKKKM.SQ....KIR......VYD...QDPL.QEDVWK.ILSGE...KDDFLIY..D.....RCGSLTH.HLGL..PY...S.ML...T.MSYVED..AIRDTYCKDICGN.CSLES.S..........SL...PV..TCNS.T.VKp............egKPEDKPEESPES....HG..H.PHA...HGHg..hHhseegrQSHR..RHSS.HGHHHGH.....GRHHHGSQQEF.....NNGQTQ..RHSQTHQQQ-q.................................................................................
A0A096M1E4_POEFO/1-185               ...............................................---------------.----------..-----------...-..HF.CL.VQ.ASRIGRL....RTKLRRSNITDVSFVIV............N..........EQ.DAASRALYWE.LKKRA.PT....GVP......VYQ...QAAN.QTDVWE.VLDGD...KDDFLIY..D.....RCGLLTF.HVVL..PY...S.SL...Q.NPYVEA..AIRATYLGDIC-N.CSAIS.T..........RT...PS..IQGT.I.Q-...............TPDEGADPTEET....QT..I.PHH...YHH....H......FSFS..HHQP.APRDKSQ.....D-QHRS-----.....------..----------aifpapyhphhah.....................................................................
SELPB_DANRE/28-263                   ..............................................n-GSRICKPAPQWEID.GKTPMKELLG..NVVVVALLKAS...U..HF.CL.TQ.AARLGDL....RDKLANGGLTNISFMVV............N..........EQ.DSQSRAMYWE.LKRRT.AQ....DIP......VYQ...QSPL.QNDVWE.ILEGD...KDDFLVY..D.....RCGYLTF.HIVL..PF...S.FL...H.YPYIEA..AIRATYHKNMC-N.CSLNA.N..........FS...IS..ESSD.S.TK...............NDPAGENNQRPN....ST..E.PVT...AAH....H......HHHQ..QHEP.HHHHHNP....yPNSHKKSGDSD....vTGKPKE..PPHHSHQEH-vhn...............................................................................
I3KDC0_ORENI/1-102                   ..............................................l---------------.----------..-----------...-..-F.CL.VQaSSRLDGL....QQKLERQGLKNVVYMVV............N..........HQ.GEQSRHLHPL.LEAKL.SK....NII......LYK...QDGH.QPDVWQ.TLAGE...KDDFFIY..D.....RCGRLTY.RISL..PY...S.II...G.EGHIE-..-------------.-----.-..........--...--..----.-.--...............------------....--..-.---...---....-......----..----.-------.....-----------.....------..----------..................................................................................
U3KMC5_RABIT/1-197                   ...............................................---------------.----------..-----------...-..YL.CI.LQ.ASRLEEL....RVKLEKEGYSNISYVVI............N..........HQ.GIDSQLKYIH.LKNKV.SH....HIL......VYQ...QEEN.QTDVWT.LLKGS...KDDFLIY..D.....RCGRLVY.HLAL..PY...S.FL...T.FPYVEE..AIKIAYCEETCGN.CSLMT.P..........ED...ES..FCKN.V.SL...............ATVEKVSEA---....--..-.LRP...HHH....-......--HT..HHHK.HGHQHLD.....SSELSEKQHPG....tPDAPLH..LPPSGLHHHHkhrdqhrqg.........................................................................
H2ZVW4_LATCH/23-227                  ..............................................g-KSTRCKEPPTWYIG.EENPMLESRG..KVTVVALLQAS...S..FY.II.LY.VSRMDDL....HLKLENEGLVNISYMIV............N..........HQ.GEYSQHKHNL.LKQRV.SE....FIP......VYK...QDME.KPNVWN.LLNGN...KDDFLIY..D.....RCGRLVY.HLGL..PY...S.VL...H.FPYMEE..AIRIAFCETRCGN.CSFTV.K..........DI...NE..ICNR.T.E-...............-NTDEPVEEPPP....TS..V.PDP...PQQnpqhH......GAHR..HHRQ.HGH----.....-----------.....------..----------q.................................................................................
G3WG53_SARHA/1-198                   ...............................................---------------.----------..-----------...-..YL.CI.LQ.ASRLEDL....RVKLEREGFSNISYIVV............N..........HQ.GNPSQLNFKE.LKDKV.SE....NIT......VYQ...QEVN.QQDVWT.VLNGS...KDDFLIY..D.....RCGRLVY.HLGL..PY...T.FL...T.FSYVEE..AIKVAYCEKSCGN.CSYTT.I..........DD...ES..FCKN.A.SS...............VAEEEPTRTPTS....HP..P.HHH...LRH....H......HDHH..HHHH.HHQHHRH.....GHQPTENKKPE.....DSETAAdvHSAQGLHHHH..................................................................................
A0A0N5B269_STREA/64-247              ....................................neifqlnrmae---------------.----------..-----------...-..--.--.--.-------....-------TLHDIKFLIL............I..........SK.EFDNRYLNA-.-WSNK.YK....YIS......ILQ...QDGG.QFDPYY.YLNAN...DDDRLLF..D.....RCGRLAV.-VRK..KQ...K.ID...E.TSFLEEfnMLSQSKYHALCGW.CKYDI.S..........KR...LP..ESAE.D.FN...............KYVQQETNVNTL....RD..G.NYR...QRN....N......NIN-..----.-------.....-----------.....------..----------tynnndqiysknykynssqkelfdrkisvtqnptikv.............................................
#=GC seq_cons                        .......................................................................................................phttL....t.phtttsh.slpahlV............N..........pp.s..uphha...Lcpph.s.....tls......lap...Q-tt.p.-lWp.hLsGs...KDDFllY..D.....RCGRLsa.Hltl..Pa...S.hL...p.asYVEt..AI+.sapcphCGs.Cshps............pt....p...spt.......................t...............................................................................................t.................................................................................
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