GenomeNet

Database: Pfam
Entry: SelP_N
LinkDB: SelP_N
Original site: SelP_N 
#=GF ID   SelP_N
#=GF AC   PF04592.10
#=GF DE   Selenoprotein P, N terminal region
#=GF AU   Kerrison ND
#=GF SE   DOMO:DM04433;
#=GF GA   23.20 23.20;
#=GF TC   23.80 23.50;
#=GF NC   22.70 23.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Selenoprotein_P
#=GF RN   [1]
#=GF RM   10775431
#=GF RT   Selenoprotein P: properties, functions, and regulation. 
#=GF RA   Mostert V; 
#=GF RL   Arch Biochem Biophys 2000;376:433-438.
#=GF RN   [2]
#=GF RM   11168591
#=GF RT   Selenium metabolism in zebrafish: multiplicity of selenoprotein
#=GF RT   genes and expression of a protein containing 17 selenocysteine
#=GF RT   residues. 
#=GF RA   Kryukov GV, Gladyshev VN; 
#=GF RL   Genes Cells 2000;5:1049-1060.
#=GF RN   [3]
#=GF RM   9358058
#=GF RT   Analysis of bovine selenoprotein P-like protein gene and
#=GF RT   availability of metal responsive element (MRE) located in its
#=GF RT   promoter. 
#=GF RA   Fujii M, Saijoh K, Kobayashi T, Fujii S, Lee MJ, Sumino K; 
#=GF RL   Gene 1997;199:211-217.
#=GF DR   INTERPRO; IPR007671;
#=GF CC   SelP is the only known eukaryotic selenoprotein that contains
#=GF CC   multiple selenocysteine (Sec) residues, and accounts for more
#=GF CC   than 50% of the selenium content of rat and human plasma [1]. 
#=GF CC   It is thought to be glycosylated [2].  SelP may have antioxidant
#=GF CC   properties.  It can attach to epithelial cells, and may protect
#=GF CC   vascular endothelial cells against peroxynitrite toxicity [1].
#=GF CC   The high selenium content of SelP suggests that it may be
#=GF CC   involved in selenium intercellular transport or storage [2]. The
#=GF CC   promoter structure of bovine SelP suggest that it may be
#=GF CC   involved in countering heavy metal intoxication, and may also
#=GF CC   have a developmental function [3]. The N-terminal region of SelP
#=GF CC   can exist independently of the C terminal region.  Zebrafish
#=GF CC   selenoprotein Pb (Swiss:Q98SV0) lacks the C terminal Sec-rich
#=GF CC   region, and a protein encoded by the rat SelP gene and lacking
#=GF CC   this region has also been reported [2]. N-terminal region
#=GF CC   contains a conserved SecxxCys motif, which is similar to the
#=GF CC   CysxxCys found in thioredoxins.  It is speculated that the N
#=GF CC   terminal region may adopt a thioredoxin fold and catalyse redox
#=GF CC   reactions [2]. The N-terminal region also contains a His-rich
#=GF CC   region, which is thought to mediate heparin binding.  Binding to
#=GF CC   heparan proteoglycans could account for the membrane binding
#=GF CC   properties of SelP [1].  The function of the bacterial members
#=GF CC   of this family is uncharacterised.
#=GF SQ   128
#=GS A1E951_PIG/23-266        AC A1E951.3
#=GS H0ZC10_TAEGU/1-47        AC H0ZC10.1
#=GS H2SF16_TAKRU/1-110       AC H2SF16.1
#=GS U6PFR9_HAECO/21-220      AC U6PFR9.1
#=GS G3W9K6_SARHA/23-176      AC G3W9K6.1
#=GS G3ID68_CRIGR/21-166      AC G3ID68.1
#=GS G1KY65_ANOCA/23-58       AC G1KY65.1
#=GS SEPP1_PONAB/23-249       AC Q5R8W9.2
#=GS H1A5G2_TAEGU/1-124       AC H1A5G2.1
#=GS S4RZM2_PETMA/24-181      AC S4RZM2.1
#=GS G3PMU8_GASAC/1-188       AC G3PMU8.1
#=GS W5MN82_LEPOC/23-267      AC W5MN82.1
#=GS T1RTU8_CARAU/1-97        AC T1RTU8.1
#=GS A8Q426_BRUMA/7-208       AC A8Q426.2
#=GS W4Z1T3_STRPU/83-177      AC W4Z1T3.1
#=GS R0LFN8_ANAPL/101-212     AC R0LFN8.1
#=GS Q6DJ72_XENTR/13-254      AC Q6DJ72.1
#=GS U3IXD6_ANAPL/13-195      AC U3IXD6.1
#=GS W0T6H2_KLUMA/126-283     AC W0T6H2.1
#=GS W4X313_ATTCE/135-288     AC W4X313.1
#=GS M9P1D6_MELGA/1-107       AC M9P1D6.1
#=GS E2AE76_CAMFO/129-280     AC E2AE76.1
#=GS E0CX80_MOUSE/23-139      AC E0CX80.1
#=GS B0W3C3_CULQU/144-295     AC B0W3C3.1
#=GS M4A9J5_XIPMA/5-210       AC M4A9J5.1
#=GS F4X476_ACREC/178-323     AC F4X476.1
#=GS A6GDZ9_9DELT/130-246     AC A6GDZ9.1
#=GS V9L2I8_CALMI/43-221      AC V9L2I8.1
#=GS M3YSM4_MUSPF/1-167       AC M3YSM4.1
#=GS F7EK34_ORNAN/12-166      AC F7EK34.1
#=GS A2I5C2_MYTGA/1-97        AC A2I5C2.1
#=GS A7RTX8_NEMVE/23-190      AC A7RTX8.1
#=GS SEPP1_BOVIN/23-290       AC P49907.2
#=GS V5GWR4_IXORI/1-204       AC V5GWR4.1
#=GS A9JRW5_DANRE/23-254      AC A9JRW5.2
#=GS F6PUF8_HORSE/23-250      AC F6PUF8.1
#=GS J9FD25_WUCBA/10-174      AC J9FD25.1
#=GS H3DJR4_TETNG/1-201       AC H3DJR4.1
#=GS Q9BDE2_BOVIN/1-126       AC Q9BDE2.1
#=GS Q9BDE3_BOVIN/1-126       AC Q9BDE3.1
#=GS Q6P3K0_DANRE/23-255      AC Q6P3K0.2
#=GS H2PXQ5_PONAB/1-188       AC H2PXQ5.2
#=GS F6Q9N1_XENTR/23-205      AC F6Q9N1.1
#=GS Q9BDE5_BOVIN/1-140       AC Q9BDE5.1
#=GS C3YH40_BRAFL/68-195      AC C3YH40.1
#=GS H0UZB3_CAVPO/1-141       AC H0UZB3.1
#=GS E5SI43_TRISP/46-261      AC E5SI43.1
#=GS B7Q2F3_IXOSC/1-206       AC B7Q2F3.1
#=GS A8Q424_BRUMA/15-222      AC A8Q424.1
#=GS SELPA_DANRE/23-255       AC Q98SV1.3
#=GS W5M4W3_LEPOC/1-173       AC W5M4W3.1
#=GS W5MN70_LEPOC/1-198       AC W5MN70.1
#=GS G3WG53_SARHA/1-198       AC G3WG53.1
#=GS U3KMC5_RABIT/1-197       AC U3KMC5.1
#=GS G1KQP6_ANOCA/26-179      AC G1KQP6.1
#=GS V5IEV8_IXORI/1-203       AC V5IEV8.1
#=GS W2T5A9_NECAM/19-178      AC W2T5A9.1
#=GS U6P7T9_HAECO/21-226      AC U6P7T9.1
#=GS A0A023G782_9ACAR/1-127   AC A0A023G782.1
#=GS F1C7F1_PERFV/1-101       AC F1C7F1.1
#=GS R7VML4_COLLI/1-120       AC R7VML4.1
#=GS E0CZ76_MOUSE/23-124      AC E0CZ76.1
#=GS Q7Q0I7_ANOGA/166-293     AC Q7Q0I7.4
#=GS F6V1E8_ORNAN/23-255      AC F6V1E8.2
#=GS W5JI27_ANODA/146-291     AC W5JI27.1
#=GS V4A4R8_LOTGI/1-157       AC V4A4R8.1
#=GS W5L435_ASTMX/10-143      AC W5L435.1
#=GS G1LAZ4_AILME/4-242       AC G1LAZ4.1
#=GS A0A023G9S4_9ACAR/1-127   AC A0A023G9S4.1
#=GS SEPP1_RAT/23-248         AC P25236.2
#=GS E9QB63_DANRE/23-254      AC E9QB63.1
#=GS X1YM66_ANODA/533-676     AC X1YM66.1
#=GS G3NUN5_GASAC/1-216       AC G3NUN5.1
#=GS D6REX5_HUMAN/23-249      AC D6REX5.1
#=GS B5DDI2_DANRE/1-173       AC B5DDI2.1
#=GS F6VJE4_XENTR/25-266      AC F6VJE4.1
#=GS U3K9A0_FICAL/19-264      AC U3K9A0.1
#=GS F1RD74_DANRE/28-263      AC F1RD74.1
#=GS U3JR44_FICAL/27-249      AC U3JR44.1
#=GS V8NYH9_OPHHA/29-180      AC V8NYH9.1
#=GS H9KP47_APIME/87-182      AC H9KP47.1
#=GS G3UU18_MELGA/1-166       AC G3UU18.1
#=GS R4GMT5_HUMAN/23-77       AC R4GMT5.1
#=GS W5PG55_SHEEP/23-207      AC W5PG55.1
#=GS V8PHU7_OPHHA/20-55       AC V8PHU7.1
#=GS A0A044QQ64_ONCVO/31-263  AC A0A044QQ64.1
#=GS E0CY03_MOUSE/33-110      AC E0CY03.1
#=GS Q16FG7_AEDAE/94-251      AC Q16FG7.1
#=GS SEPP1_MOUSE/23-268       AC P70274.3
#=GS A0A024R054_HUMAN/72-107  AC A0A024R054.1
#=GS M3XHZ2_LATCH/1-183       AC M3XHZ2.1
#=GS H6WVW6_CAPHI/23-243      AC H6WVW6.1
#=GS J0XLE8_LOALO/31-255      AC J0XLE8.1
#=GS Q4RPX4_TETNG/1-182       AC Q4RPX4.1
#=GS Q9N0N7_CAPHI/23-205      AC Q9N0N7.1
#=GS R4GJB1_CHICK/1-203       AC R4GJB1.1
#=GS J9NST4_CANFA/1-138       AC J9NST4.1
#=GS G3TLW1_LOXAF/23-207      AC G3TLW1.1
#=GS F4X476_ACREC/858-966     AC F4X476.1
#=GS A6FZW7_9DELT/137-264     AC A6FZW7.1
#=GS V5H5E6_IXORI/1-200       AC V5H5E6.1
#=GS H2UNP3_TAKRU/23-253      AC H2UNP3.1
#=GS K7FTE4_PELSI/15-167      AC K7FTE4.1
#=GS H3DGX7_TETNG/23-251      AC H3DGX7.1
#=GS G5APA7_HETGA/37-233      AC G5APA7.1
#=GS Q9BDE4_BOVIN/1-126       AC Q9BDE4.1
#=GS M4ANC2_XIPMA/23-205      AC M4ANC2.1
#=GS F1N9T1_CHICK/1-159       AC F1N9T1.2
#=GS E0CZC5_MOUSE/23-177      AC E0CZC5.1
#=GS I6SJ59_BUBBU/23-264      AC I6SJ59.2
#=GS H3CE96_TETNG/6-134       AC H3CE96.1
#=GS D2XNK7_SACKO/23-265      AC D2XNK7.1
#=GS G1Q9G6_MYOLU/23-202      AC G1Q9G6.1
#=GS I3JR88_ORENI/1-180       AC I3JR88.1
#=GS D6RIS9_HUMAN/23-209      AC D6RIS9.1
#=GS W5KEM0_ASTMX/23-259      AC W5KEM0.1
#=GS G9KN32_MUSPF/1-156       AC G9KN32.1
#=GS SEPP1_HUMAN/23-249       AC P49908.3
#=GS M1EV50_MELGA/1-100       AC M1EV50.1
#=GS Q5PR33_DANRE/28-263      AC Q5PR33.2
#=GS I3LJP2_PIG/5-135         AC I3LJP2.1
#=GS H2MB78_ORYLA/1-159       AC H2MB78.1
#=GS K7E6A4_MONDO/1-186       AC K7E6A4.1
#=GS K7JYM3_NASVI/162-308     AC K7JYM3.1
#=GS SELPB_DANRE/28-263       AC Q98SV0.3
#=GS I3KDC0_ORENI/1-102       AC I3KDC0.1
#=GS H2ZVW4_LATCH/23-227      AC H2ZVW4.1
#=GS K7F0S1_PELSI/23-58       AC K7F0S1.1
A1E951_PIG/23-266                   ................................................g-KSSFCEQPPGWSIK..DQDPMLNSYG..SVTVVALLQAS...U..YL.CILQ.ASRLEDL....RVKLEKEGYSNISYIVVN....HQGIASQLKYVY.LKSKV.SE....HIPVYQ...QEENQTDVWT.LLNGN...KDDFLIY..D..RCGLLVYHLGL..PYS.FL...T.FPY...VEEAIKTVYCE.NKCGN.CSLKT.L..........KD...ED.FCKN.V.YL...............ATEEKTT..EAPQP....HH..H.HDH...HHH....-......--.RH..HH...HH.HGHQHLG.....NGHLSEHPKPE....aPDAPEQ..PPPSGLHHHHghkghqrqghsen.............................................................................
H0ZC10_TAEGU/1-47                   .................................................---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...KDDFLVY..D..RCGRLAFHIQL..PFS.FL...H.FPY...VEAAIRSSHIK.DFCGN.CSL--.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
H2SF16_TAKRU/1-110                  .................................................---------------..----------..-----------...-..--.----.--RIGGL....RKKLIQSNMTEVSYMIVN....EQDPHSRALFWE.LERRA.PP....DVPVYQ...QSAFQSDVWE.TLDGD...KDDFLIY..D..RCGQLTFHVGL..PYS.FL...N.YVY...VEAAIRATYQG.NIC-N.CSV--.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------s.........................................................................................
U6PFR9_HAECO/21-220                 .............................................rhsl-----CS-TPTLTVR..GVDIVAASKN..TVLVVAFMPLQ...C..AS.CHRQ.LKRLSYL....ATN-----QNDVRVVVL-....APSYEA----PV.TIARV.QT....EFPRLV...IDRDTHNVWR.LYEAA...NHDQMFF..D..KCGRVTQVIQH..PRS.DM...TnYRD...TLYAVDSARTQ.RTCGP.CSNGG.S..........RE...PL.QQHA.S.SG...............RYEEHQ-..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------rarpsftiranyntrappitnngrstytqspqvnnq......................................................
G3W9K6_SARHA/23-176                 ................................................n-GTRICQPAPDWQVD.gGVSPMEEALG..NVTEVALLKAP...L..TR.P-FL.APRIGSL....QERLARAGTAGVRFLIVN....HKSAAAQALQGE.LELRA.PR....GVPVYS...QRGPRPDIWG.LLGGA...KDDFLVY..D..RCGRLTFHIQL..PFS.AL...S.FPF...VEAAVRFSHQQ.DHCGN.CS---.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
G3ID68_CRIGR/21-166                 ..........................................cdrpdgp---------------..----------..-----------...-..--.----.-NRLEDL....RLKLENQGYSNISYIIVN....HQGSPSQLKHTH.LKNHV.SD....QIAVYR...QEEHQTDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FPY...VEEAIKIAYCE.KKCRN.CSFTL.L..........RV...KR.R---.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------sprrhitttstitntgtgfl......................................................................
G1KY65_ANOCA/23-58                  ...............................................gp--STRCKEPPDWRIG..EQNPMLDSRG..FVTVVALLQAS...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-----------..---.--...-.---...-----------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
SEPP1_PONAB/23-249                  ................................................d-QSSLCKQPPAWSIR..DQGPMLNSNG..SVTVVALLQAS...U..YL.CILQ.ASKLEDL....RVKLKKEGYSNISHIVVN....HQGISSRLKYTH.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGS...KDDFLIY..D..RCGRLVYHLGL..PFS.FL...T.FPY...VEEAVKIAYCE.KKCGY.CSLTT.L..........KD...ED.FCKS.V.SL...............ATVDKTV..EA---....--..-.PSP...HYH....-......--.HE..HH...HN.HRHQHLG.....SSELSENQQPG....aPDAPTH..PAPPGLHHHHkh........................................................................................
H1A5G2_TAEGU/1-124                  .................................................---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...KDDFLIY..D..RCGRLVYHLGM..PYS.FL...H.FQY...VEESIKIAYCE.NKCGN.CSYME.P..........DA...DG.VCEN.I.TK...............KAVEELS..EIEPK....PT..G.QHS...HPNl..hR......HG.HH..QR...HH.HHHHHHKg...sRDPKHENHQAA.....AEAERH..HPHS------g.........................................................................................
S4RZM2_PETMA/24-181                 ..............................................ape---AKCKRPPVWSLGggGAMPMRERLG..SVVVLALLKRI...C..YM.FVMRvFAILKEL....RAHLWKEGLRGIHYLIVN....DNSSASLARYEH.LKAQV.PP....AIPVLQ...HAPNDTDVWS.TLGGT...KDDFFIY..D..RCGRLVAKVGL..PLS.IL...A.FPY...VDEAVRRAYFTlDVCGP.CN---.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
G3PMU8_GASAC/1-188                  .................................................---------------..----------..-----------...-..--.----.-------....--------------MIVN....EREPHSRAMYWE.LKRRA.PP....GVPVYQ...QAALQSDVWE.ALDGD...KDDFLVY..D..RCGLLTFHIVL..PYS.FL...H.NVY...VEAAIRATYLK.NIC-N.CTVDS.VvsslnnsvmnN-...--.----.E.TDfnvsqtnatpriqpdTNDPEGA..GTPPP....PT..H.HHS...HHH....H......HH.HQ..HH...HP.HHPHHAH....lNQPLHDTSQNI.....TRHPLS..VHHHHH----phhhh.....................................................................................
W5MN82_LEPOC/23-267                 ...............................................gg--GGRCKTPPEWAVG..NEQPMTDSAG..RVTVVALLQLN...Y..LVqNLIF.LNRLDVL....RLRLEQQGLVNISYVVVN....HQGEQSHRLYPV.LKKKM.SQ....KIRVYD...QDPLQEDVWK.ILSGE...KDDFLIY..D..RCGSLTHHLGL..PYS.ML...T.MSY...VEDAIRDTYCK.DICGN.CSLES.S..........SL...PV.TCNS.T.VKp............egKPEDKPE..ESPES....HG..H.PHA...HGHg..hHhseegrQS.HR..RH...SS.HGHHHGH.....GRHHHGSQQEF.....NNGQTQ..RHSQTHQQQ-q.........................................................................................
T1RTU8_CARAU/1-97                   ................................................r---------------..----------..-----------...-..--.----.-------....------------------....-----SQEMHHL.LKERL.M-....NITLYA...QDLSQPDIWQ.AVNAE...KDDILVY..D..RCGRLTYHLSL..PYT.IL...S.HPH...VEEAIRLTYCD.GICGE.CSIES.S..........LQ...LE.QCKK.S.T-...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------de........................................................................................
A8Q426_BRUMA/7-208                  .............................................stpi----LCSQTKSWKLG..GRDIIADSKG..FVLLVALMPME...C..EH.CHEQ.LMKFQTV....MET-----LPEIRIVVIT....PYDENPRLIERY.RKEFS.RV....AIGI--...-ESLDERIWD.TLSGS...GHDHFIY..D..RCGRLASVIRH..PKSdTS...K.FEH...TLRALKSAISY.AQCGW.CQYDP.P..........DL...PQ.EPVI.T.T-...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------yasftrkgktrrprikavvypqngradtlssdhrstldqer.................................................
W4Z1T3_STRPU/83-177                 ...............................................ls---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-CGQLTYHIPM..PYS.AL...R.YPF...IQIAIESTYTG.RHPCN.CSADE.P..........TT...TA.MPST.-.-E...............KPHKTPS..DRKRS....LR..H.AVS...DNN....N......NN.--..--...--.-------.....-----------.....------..----------yyrksgemqsalidrtdad.......................................................................
R0LFN8_ANAPL/101-212                ..............................................xxx---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-----------..---.--...H.FPY...VESAIRFTHSK.DFCGN.CSLYP.N..........ST...HE.ANST.-.--...............--MEVPV..TPSPL....PD..Q.EEK...ESE....A......PIhHQ..HK...PL.HPHHHAG.....S----NERAPE.....PSGDHR..AAAHAHHHH-gdhsqphpkgqkqegrd.........................................................................
Q6DJ72_XENTR/13-254                 ................................................t-NSSICKPPPKWSIE..GEVPMAEALG..KVTVVALLQAS...C..GF.CLVQ.AARMGPL....RYKLSLQGMTDIKYMIVN....DQSLHSANMFPE.LKRWA.PE....GIPVYQ...QTPGQDDVWE.LLDGN...KDDFLIY..D..RCGRLTFHVRL..PLS.FL...H.FPY...VEAAILSTYNE.SFCGN.CSFTS.N..........ST...LIpMNGT.T.VSpsgdd.....sssplQNKDEPV..NKEPS....PT..L.EKH...NDQ....R......KL.DSelRL...HD.HSQHHPI.....-NSHKR-QENQ.....NNHPR-..----------nlikngkqn.................................................................................
U3IXD6_ANAPL/13-195                 ................................................t-ETQNCQEPPEWRVG..EENPMLNSRG..SVTVVALLQTS...H..NL.SVLD.HEELEDL....RVKLENEGLVNISYVVVN....HQGAYSQKKFHL.LKESV.SE....YITVYQ...QDEHQADVWT.TLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...S.FNY...VEEAIKIAYCE.NKCGN.CSYTE.P..........DI...DA.TCEN.I.TK...............KADEKLA..EVEPK....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------ps........................................................................................
W0T6H2_KLUMA/126-283                elkhdgkelkvsskkdeidqifeldeevddvevtkicltedmndavlgl---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-----------..--R.LI...K.KVT...VEEPIRSVDCH.SDEDQ.PTSYD.I..........LM...TE.DCDS.R.EEp............eeESKEEPK..EEPKE....EQ..V.EEPkkeHKK....R......HR.HR..HH...RH.HHHHHRS.....-ESLSNDESLK....qDQAV--..----------sspnkesllas...............................................................................
W4X313_ATTCE/135-288                ....................................vnsdflknngtei---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....---IFL...QDDPQSRIWE.RFRAS...REHAVII..D..RCGKLTYHVIV..PWS.IL...F.FPY...VKAAILSTYMD.DPCGG.CNPAV.Y..........QA...SN.HENH.V.VEl............tkSTKKDLS..TKKDS....SY..R.EID...TKFe.iiW......TT.ES..LP...EN.LTHLHHE.....SSSEEERE---.....------..----------tstassillen...............................................................................
M9P1D6_MELGA/1-107                  ................................................l---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-----------..---.--...-.-PY...VESAIRFTHRK.DFCGN.CSLYT.N..........SS...QE.ANST.M.E-...............----VPT..TLTPL....PK..Q.EEK...ESE....T......PA.HH..QP...NHlHPHHHAV.....----GSRTAPE.....PSGDHR..PA-HTHHHH-gahgqlhpkgqtpeghd.........................................................................
E2AE76_CAMFO/129-280                ......................................tnlffedsese---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....--IIFL...QDDPQFRIWE.RFRAS...KDQVVVI..D..RCGQLTYQIMV..PWS.IL...Y.FPY...VKAAILSTHQE.DPCGG.CDPTM.Y..........QD...PD.YEDY.F.PN...............-SRSTTK..GTDQ-....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------yetdkinaeliwtteqwssgngsvhleeslkeehetnivppvisdkithds.......................................
E0CX80_MOUSE/23-139                 ................................................g-QSSACYKAPEWYIG..DQNPMLNSEG..KVTVVALLQAS...C..YL.CLLQ.ASRLEDL....RIKLESQGYFNISYIVVN....HQGSPSQLKHSH.LKKQV.SE....HIAVYR...QEEDGIDVWT.LLNGN...KDDFLIY..D..R----------..---.--...-.---...-----------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
B0W3C3_CULQU/144-295                ............................................aagyn---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....-ISVYP...NPLNENGTYA.MYGLK...EFQVYVL..D..RCSRIAYIIEP..PWS.LI...Q.YSY...VKAAVLSTLYD.RPCGE.CDVDN.F..........LN...SS.LPVQ.K.MA...............ELQQMPT..AKSTS....TT..T.TTT...TTT...eP......SS.SS..TS...--.-------.....-----------.....------..----------astprsdvrpyddstesdepmateeyseppeptttee.....................................................
M4A9J5_XIPMA/5-210                  .........................................vqasrltq---------------..----------..---ITALIQTD...D.kRI.SKNY.WNNIGRL....RTKLRRSNVTDVSFLIVN....EQNAVSRALYWE.LKKRA.PT....GVPVYQ...QDANQTDVWE.VLDGD...KDDFLIY..D..RCGLLTFHVVL..PYS.FM...H.NPY...VEAAIRATYVG.DIC-N.CSAIS.T..........RT...PD.TVQP.P.D-...............EGVDPTE..KTQPI....PH..H.YHH...LSS....-......--.FF..HH...QP.APRNKTQ.....-DQDRPVIFPA.....PYHPHH..AHQH------phhk......................................................................................
F4X476_ACREC/178-323                .....................................vnsdflknnete---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....--IIFL...QDDPQSRIWE.RFRAS...REHAVII..D..RCGMLTYHVIV..PWS.IL...F.FPY...VKAAILSTYMD.DPCGE.CNPAV.Y..........RA...SN.HEDH.V.VE...............LTKSTKK..ELNPS....YR..E.VDT...KFEi..iW......TT.ES..LP...EN.LTHLHYE.....-----------.....------..----------ssseeeretsiassi...........................................................................
A6GDZ9_9DELT/130-246                ............................................fqpqs-----------CNFG..ETTSLEAYKG..RVTLVTLMRTT...C..EI.CQGT.IEKLEEM....RLELELDGY-DVYFLAIN....QMGYESTQQ--E.FIDRV.AF....--PL-L...QDTAEVDAWE.LLNDTglgTDDIYIY..G..ADGSL------..---.--...-.---...-----------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------rsyfn.....................................................................................
V9L2I8_CALMI/43-221                 ................................................q-ESRICQAAPLWEIA..NQNPMEQQLG..SVVVVALLKAS...U..QF.CLTQ.AAKLGSL....QDKLARQGLKDVHYMIVN....EKAPESRAMLWE.LKRHV.PN....NVSVYQ...QSPIQPDVWH.SLQGG...KDDFLIY..D..RCGRLTFHVVL..PYS.SL...Q.YPY...IEAAIRATHKR.DICGE.CTITK.S..........SL...EM.DRNV.T.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------ttpsrhlspnts..............................................................................
M3YSM4_MUSPF/1-167                  ................................................m---------------..----------..-----------...-..--.----.-------....------------------....-----------N.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGK...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FPY...VEEAIKIAYCE.EKCGN.CSLTT.L..........EA...KD.FCEM.V.SS...............PTVGNTT..EAPQP....HH..H.HHH...HHH....H......LH.HH..HH...HK.HGHQHHG.....NKELSESQRPE....aPDAAEY..PAPEGLHQHHkhkthqrqghp...............................................................................
F7EK34_ORNAN/12-166                 ................................................n-GTRICQPAPRWTVN..GVAPMEGTEG..QVIVVALLKAR...S..FF.CALP.SAYLAGL....RERLAGHGAGNVSFLIVN....QRDPTAQLLHTE.LERHA.PP....GVPVYA...QDGPDPDVWS.VLGGD...KDDFFVY..D..RCGRLTFHIQL..PFS.FL...H.FPY...VEAAVRFTHRR.DFCGN.CSY--.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
A2I5C2_MYTGA/1-97                   ............................................rqeyi---------------..----------..-----------...-..--.----.-------....-----AHGRTEISFMIVN....SKEAPEQI--GQ.LSSRT.--....NFPVYQ...-DTNAINIWN.KLNGG...KDDVLIY..D..RCGKLVYFIPF..PSS.LL...R.YHL...TDWAIRTAYDT.DACG-.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------c.........................................................................................
A7RTX8_NEMVE/23-190                 ...............................................es--AGVCQRPRPWTVN..GMDPMAQARAdkQIVVLALMEAR..aC..GI.CVRQ.AKAMESLltmlRQRERSYQLGNLSFMIVN....HHMAAGSIRF--.IEGRV.S-....-FPVYQ...-ENANKQIWP.AVDGA...KDDIIVY..D..RCGGLVSHLKW..PKS.DL...T.KPH...LWQAIQRAKWS.KAC--.CKQQT.T..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------epptisdggk................................................................................
SEPP1_BOVIN/23-290                  ................................................g-QSSYCKQPPPWSIK..DQDPMLNSYG..SVTVVALLQAS...U..YL.CILQ.ASRLEDL....RVKLEKEGYSNISYVVVN....HQGISSRLKYVH.LKNKV.SE....HIPVYQ...QEENQPDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FTY...VEDSIKTVYCE.DKCGN.CSLKA.L..........ED...ED.VCKN.V.FL...............ATKEKTA..EASQR....HH..H.PHP...HSHp..hP......HP.HP..HP...HP.HPHPHHGhqlheNAHLSESPKPD....tPDTPEN..PPPSGLHHHHhrhkgpqrqghsdncdtpvgseslqps...............................................................
V5GWR4_IXORI/1-204                  .................................................---------------..----------..-----------...-..--.---Q.ASSLEAL....LLKLRARNLSDVQFLVVN....SLD--SAAEVRE.LERRV.S-....-FPVYQ...-ETANEPVWS.VLEGD...KDDVFIY..D..RCGRLSYFIPF..PLS.VTlpgR.HPV...VEEALNTTYYA.SPCGDfCPQDP.S..........AI...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------phgssphehqqqripgqietqdegetgiavsppttpseglgwrvihmvfgdghqgqvdshtpsqaqeggvttgaphdhqerhptpte...
A9JRW5_DANRE/23-254                 ................................................t-EGARCKLPPEWKVG..DVEPMKNALG..QVTVVAYLQAS...U..LF.CLEQ.ASKLNDL....LLKLENQGYPNIAYMVVN....NREERSQRLHHL.LQERL.L-....NITLYA...QDLSQPDAWQ.AVNAE...KDDILVY..D..RCGRLTYHLSL..PYT.IL...S.HPH...VEEAIKHTYCD.RICGE.CSLES.S..........AQ...LE.ECKK.A.T-...............EEVNKPV..EEEPR....QD..H.GHH..eHGHh..eH......QG.EA..ER...HR.HGHHHPHh...hHHHHRGQQQVD.....------..----------vdqqvlsqvdfg..............................................................................
F6PUF8_HORSE/23-250                 ................................................g-QSSFCKQPPAWSIR..DQDPMLNSYG..SVTVVALLQAS...C..YL.CLLQ.ASRLEDL....RVKLEKEGYSNISYVVVN....HQEISARLKYIH.LKNKV.SE....YIAVYQ...QEENQTDIWT.LLNGS...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FPY...VEEAIKIAYCE.KKCGN.CSLMT.L..........ED...ED.FCKT.L.SL...............ATVEKTT..ED---....-S..Q.PHH...HHH....-......--.HQ..HH...HK.HGHQHVG.....NSQLSENQQPE....aTGAPEH..PPPPGLHHHHk.........................................................................................
J9FD25_WUCBA/10-174                 ......eqlmkfqtvmetlseirivviapydenprlieryrkefsrvti---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....-----G...MESLDERIWD.TLSGS...GHDHFIY..D..RCGRLASVIRH..PKS.DT...SkSEH...TLRALKSAISY.AQCGW.CQYDP.P..........DL...PQ.EPVI.T.TY...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------asltrkgktrrpmavvekeadtleqfssnwflegaqfenrrnqs..............................................
H3DJR4_TETNG/1-201                  .................................................---------------..----MEALVG..RVVVVALLKAS...T..PP.CDAP.FPRIGPL....REKLSRRNVTEVSFVIVN....EQEPVSRALYWQ.LRRRA.PP....GVPVYQ...QAPLQDDVWE.ALDGD...KDDFLIY..D..RCGQLTFHIGL..PYS.SL...R.YTY...VEAAVIATYQG.NIC-N.CSANC.H..........IS...EH.QQQQ.R.K-...............-WRDAQS..DQPDG....HC..G.DRW...STH...yP......PP.PS..PS...PP.ATHTHTD.....-----------.....------..----------arpshthtsldlpppp..........................................................................
Q9BDE2_BOVIN/1-126                  .................................................---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FTY...VEDSIKTVYCE.DKCGN.CSLSR.P..........QD...ED.VCKN.V.FL...............ATKEKTA..EASQR....HH..H.P--...---....-......--.--..-H...PH.HGHQLHE.....NAHLSESPKPD....tPDTPEN..PPTSGLHHHHhrhkgpqrqgh...............................................................................
Q9BDE3_BOVIN/1-126                  .................................................---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FTY...VEDSIKTVYCE.DKCGN.CSLSR.P..........QD...ED.VCKN.V.FL...............ATKEKTA..EASQR....HH..H.PHP...HPH....-......--.--..--...--.HGHQLHE.....NAHLSESPKPD....tPDTPEN..PPTSGLHHHHhrhkgpqrq.................................................................................
Q6P3K0_DANRE/23-255                 ................................................t-EGARCKLPPEWKVG..DVEPMKNALG..QVTVVAYLQAS...U..LF.CLEQ.ASKLNDL....LLKLENQGYPNIAYMVVN....NREERSQRLHHL.LQERL.L-....NITLYA...QDLSQPDAWQ.AVNAE...KDDILVY..D..RCGRLTYHLSL..PYT.IL...S.HPH...VEEAIKHTYCD.RICGE.CSLES.S..........AQ...LE.ECKK.A.T-...............EEVNKPV..EEEPR....QD..H.GHH..eHGHh..eH......QG.EA..ER...HR.HGHHHPHh...hHHHHRGQQQVD.....------..----------vdqqvlsqvdfgq.............................................................................
H2PXQ5_PONAB/1-188                  .................................................---------------..----------..-----------...-..YL.CILQ.ASKLEDL....RVKLKKEGYSNISYIVVN....HQGISSRLKYTH.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGS...KDDFLIY..D..RCGRLVYHLGL..PFS.FL...T.FPY...VEEAIKIAYCE.KKCGN.CSLTT.L..........KD...ED.FCKS.V.SL...............ATVDKTV..EA---....--..-.PSP...HYH....-......--.HE..HH...HN.HGHQHLG.....SSELSENQQPG....aPDAPTH..PAPPGLHHHH..........................................................................................
F6Q9N1_XENTR/23-205                 ..............................................ghr---KRCKEPPEWSIG..DQNPMMQSAG..KVTVVALLQAS...R..HQ.CLG-.-FRLEDL....RLKLEKEKLVGISYVVVN....HQGRQSRAKYDL.LKSKV.SE....HIPVYQ...QEEYQPDVWS.LLKGD...KDDFFVY..D..RCGRLVQHLEL..PYS.LL...H.FPY...VEEAIRIAYCE.DKCGE.CEHKK.P..........EE...QQ.EQDK.P.VE...............EKVERPR..HHRNH....H-..-.---...RH-....-......--.--..--...--.-------.....-----------.....------..----------h.........................................................................................
Q9BDE5_BOVIN/1-140                  .................................................---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FTY...VEDSIKTVYCE.DKCGN.CSLSR.P..........QD...ED.VCKN.V.FL...............ATKEKTA..EASQR....HH..H.PHP...HPHs..hS......HP.HP..HP...HP.HPHPHHGhqlheNAHLSESPKPD....tPDTPEN..PPTSGLHHHHhrhkgpq...................................................................................
C3YH40_BRAFL/68-195                 ..............................................ggl---------------..----------..-----------...-..--.----.-------....-QKLYSEGKSDIFFGAVN....HWGWASWWYRGE.LERRA.--....NFPVYQ...-DSWSQDIWG.KLHAA...KDDILVY..D..RCGRLAYHLRL..PRA.YL...G.NTH...TEEAIRAAYRQ.SPCGP.CGTLA.G..........ET...AT.PCF-.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------trlsvirlkisqlh............................................................................
H0UZB3_CAVPO/1-141                  .................................................---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.SD....HISVYQ...QEQHQPDIWS.RLKGN...KDDILIY..D..RCGRLAYHLRM..PYS.FL...S.FPY...VEQAIKIVYCV.EKCGN.CSLKN.L..........ED...DD.FCKN.V.SL...............AA--VTT..EAPQK....HH..H.RQI...HPP....K......RG.HP..--...--.-------.....-----------.....------..----------ylgsrepeapdnpvqslplglhnlhrgqprqvh.........................................................
E5SI43_TRISP/46-261                 ..............................................dep---DICHPVPMFTNG..GQLVMTNYHG..HVTLIALMELQ...C..TL.CRTQ.ISSIVKL....SELFRENYDEPTKFLVVA....PHNESDRFV-EY.YKQYLkPY....DIGVI-...QETTAEPIWH.TLRGS...RFDFFVY..D..RCGRLNYYIPY..PQS.FM...Y.YHY...TISSLHSTHRY.IKCGP.CPSNR.Q..........DI...ST.AAVS.V.GKt.............lTDDGQWN..SNDQR....ST..F.PSE...---....-......--.--..--...--.-------.....-----------.....------..----------tssvykhhlpkyqpkyirglsgdptgen..............................................................
B7Q2F3_IXOSC/1-206                  ................................................m---------------..----------..-----------...-..--.--FQ.IISLEAL....LLKLRARNLSDVQFLVVN....SLD--SAAEVRQ.LERRV.S-....-FPVYQ...-ETADEPVWS.VLEGD...KDDVFIY..D..RCGRLSYFIPF..PLS.VMlpgR.HPV...VEEALNTTYYA.SPCGDfCPQDP.S..........AT...PH.RSS-.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------phehqqripgeiavqdggepgttvsppttpseglgwrvihmvfgdghqgqvdshtpshareggvttgaphdhqerqptpmec........
A8Q424_BRUMA/15-222                 .............................................stpi----LCSQTKSWKLG..GRDIIADSKG..FVLLVALMPME...C..EH.CHEQ.LMKFQTV....MET-----LPEIRIVVIT....PYDENPRLIERY.RKEFS.RV....AIGI--...-ESLDERIWD.TLSGS...GHDHFIY..D..RCGRLASVIRH..PKSdTS...K.FEH...TLRALKSAISY.AQCGW.CQYDP.P..........DL...PQ.EPVI.T.TY...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------asftrkgktrrpvrqdqfvryteeiakeilyrkskrenisegitle............................................
SELPA_DANRE/23-255                  ................................................t-EGARCKLPPEWKVG..DVEPMKNALG..QVTVVAYLQAS...U..LF.CLEQ.ASKLNDL....LLKLENQGYPNIAYMVVN....NREERSQRLHHL.LQERL.L-....NITLYA...QDLSQPDAWQ.AVNAE...KDDILVY..D..RCGRLTYHLSL..PYT.IL...S.HPH...VEEAIKHTYCD.RICGE.CSLES.S..........AQ...LE.ECKK.A.T-...............EEVNKPV..EEEPR....QD..H.GHH..eHGHh..eH......QG.EA..ER...HR.HGHHHPHh...hHHHHRGQQQVD.....------..----------vdqqvlsqvdfgq.............................................................................
W5M4W3_LEPOC/1-173                  ................................................m---------------..----------..-----------...-..--.----.-------....---------TDVGFLIVN....EREPVSRAMFWE.LKRRA.PE....GIPVYQ...QGLFQSDVWE.ILEGE...KDDFLIY..D..RCGLLTFHIVL..PYS.FL...H.YPY...VEAAIRATYLR.DICGN.CTLDS.S..........DN...QG.LNAS.Q.IP...............ERKENVT..DAECL....DD..H.EQH...QGE....Q......SN.GP..QP...SR.HSQAHHS.....GHRLVHGPCRD.....KGRKRP..P---------spqnstl...................................................................................
W5MN70_LEPOC/1-198                  .................................................---------------..----------..-----------...-..--.----.---LDVL....RLRLEQQGLVNISYVVVN....HQGEQSHRLYPV.LKKKM.SQ....KIRVYD...QDPLQEDVWK.ILSGE...KDDFLIY..D..RCGSLTHHLGL..PYS.ML...T.MSY...VEDAIRDTYCK.DICGN.CSLES.S..........SL...PV.TCNS.T.VKp............egKPEDKPE..ESPES....HG..H.PHA...HGHg..hHhseegrQS.HR..RH...SS.HGHHHGH.....GRHHHGSQQEF.....NNGQTQ..RHSQTHQQQ-q.........................................................................................
G3WG53_SARHA/1-198                  .................................................---------------..----------..-----------...-..YL.CILQ.ASRLEDL....RVKLEREGFSNISYIVVN....HQGNPSQLNFKE.LKDKV.SE....NITVYQ...QEVNQQDVWT.VLNGS...KDDFLIY..D..RCGRLVYHLGL..PYT.FL...T.FSY...VEEAIKVAYCE.KSCGN.CSYTT.I..........DD...ES.FCKN.A.SS...............VAEEEPT..RTPTS....HP..P.HHH...LRH....H......HD.HH..HH...HH.HHQHHRH.....GHQPTENKKPE.....DSETAAdvHSAQGLHHHH..........................................................................................
U3KMC5_RABIT/1-197                  .................................................---------------..----------..-----------...-..YL.CILQ.ASRLEEL....RVKLEKEGYSNISYVVIN....HQGIDSQLKYIH.LKNKV.SH....HILVYQ...QEENQTDVWT.LLKGS...KDDFLIY..D..RCGRLVYHLAL..PYS.FL...T.FPY...VEEAIKIAYCE.ETCGN.CSLMT.P..........ED...ES.FCKN.V.SL...............ATVEKVS..EA---....--..-.LRP...HHH....-......--.HT..HH...HK.HGHQHLD.....SSELSEKQHPG....tPDAPLH..LPPSGLHHHHkhrdqhrqg.................................................................................
G1KQP6_ANOCA/26-179                 ................................................n-KTRICQPAPLWKIN..GTAPMAGMEG..QVTVVALLKAS...M..LV.ISLP.AISIGGL....QKKLSNEGVANVSFLIVN....EKTPLSRAMYWE.LKRNA.PQ....GIPVYQ...QQILEPDVWQ.ILDGD...KDDFLIY..D..RCSRLTFHIQL..PYS.FL...H.LPY...VEAAVHYTHRK.DYCGN.CS---.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
V5IEV8_IXORI/1-203                  .................................................---------------..----------..-----------...-..--.---Q.ASSLEAL....LLKLRARNLSDVQFLVVN....SLD--SAAEVRE.LERRV.S-....-FPVYQ...-ETANEPVWS.VLEGD...KDDVFIY..D..RCGRLSYFIPF..PLS.VTlpgR.HPV...VEEALNTTYYA.SPCGDfCPQD-.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------psaiphgssphehqqqripgqidtqgegetgiavsppttpseglgwrvihmvfgdghqgqinshtpsqaqeggvttgaphdhqerhptpm
W2T5A9_NECAM/19-178                 ........................................khslcttsv-----------LHVR..GRDIVQASRG..SVLLVVFMPLQ...C..AS.CHRQ.LKRLSYM....ASTL-----GDIRVVVL-....APSYEAPVTISR.IQNEF.PR....----LI...IDRDIDKVWR.AYEAS...NHDQIVF..D..RCNRVAHVLSH..PRSdMT...S.YRD...TLDAIDSARDH.APCGP.CQHDV.N..........RN...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------dlntgsrktak...............................................................................
U6P7T9_HAECO/21-226                 .............................................rhsl-----CS-TPTLTVR..GVDIVAASKN..TVLVVAFMPLQ...C..AS.CHRQ.LKRLSYL....ATN-----QNDVRVVVLA....----PSYEA-PV.TIARV.QA....EFPRLV...IDRDTHNVWR.LYEAA...NHDQMFF..D..KCGRVTQVIQH..PRS.DM...TnYRD...TLYAVDSARTQ.RTCGP.CGNGG.S..........RE...PL.QQHA.S.S-...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------gryeehqrarpsftiranyntrappianngrstytqppqvnnqnygsaq.........................................
A0A023G782_9ACAR/1-127              ................................................m---------------..----------..-----------...-..--.----.-------....---------SDLQFLVVN....DR--HSAHLRGH.LEQRV.SF....SV---H...QETEQEPAWS.ILDGS...KDDVFIF..D..RCGRLSYYVPF..PIS.LV...L.PGYlpvVEDALRRTYEG.TPCGL.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------lcpepadrttratqrhslgwrllhmfsstgepdke.......................................................
F1C7F1_PERFV/1-101                  ................................................l---------------..----------..-----------...-..-F.CLVQ.ASRMDDL....RQKLEDQGLKDVVYMVVN....QQAEQARRLHTM.LAQRM.SE....NITLYK...QDEQQPDVWK.TLSGQ...KDDFLIY..D..RCGRLTYHISL..PYS.II...G.HGH...VE---------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
R7VML4_COLLI/1-120                  .................................................---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...S.FQY...VEEAIKIAYCE.NKCGN.CSYTE.P..........DI...DG.ICEN.I.TK...............TAEEELA..EIAPE....PA..G.QHS...HHH....-......NL.HR..HR...HH.HHHHHRE.....GGRHSKNENHQ.....ASESHR..HHSH------sg........................................................................................
E0CZ76_MOUSE/23-124                 ................................................g-QSSACYKAPEWYIG..DQNPMLNSEG..KVTVVALLQAS...C..YL.CLLQ.ASRLEDL....RIKLESQGYFNISYIVVN....HQGSPSQLKHSH.LKKQV.SE....HIAVYR...QEEDGIDVW-.-----...-------..-..-----------..---.--...-.---...-----------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
Q7Q0I7_ANOGA/166-293                ...........................................lfglre---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...---FQVYviD..RCSRVSYIIQP..PWS.LI...Q.YAY...VKAAVLSTFYD.RPCGK.CELEN.F..........LN...ST.LTDG.EkLS...............DVKADPT..KDATP....Y-..D.DAS...DEF....S......NP.AE..EE...ED.----HDG....gVRAYSEEEDDD.....DE----..----------sdtdgngrtvdeyka...........................................................................
F6V1E8_ORNAN/23-255                 ................................................s-ASSHCKEAPRWQIR..DQDPMLNSLG..TVTVVALLQASsiiC..IF.FLLK.PFRLEDL....RVKLENEGYSNISYIIVN....HQGMPSQLNHKT.LKEKV.SE....HIPVYQ...QDEKQTDVWS.TLKGN...KDDFLIY..DrsRCGRLVYHLSL..PYT.FL...S.FSY...VEDSIKTTYCE.QNCGN.CSYTM.P..........EA...EE.FCTN.T.SS...............AAKEKAT..EA-PL....PH..N.DRP...HHH....-......--.H-..-H...HH.HHHGHKP.....HPSGTEQAPAD.....PDGPLR.sPAPQGLHK--rl........................................................................................
W5JI27_ANODA/146-291                ............................adernltvypnpltengtfal---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-LGLR...EFQVYVI..D..RCSRVSYIIEP..PWS.LI...Q.FSY...VKAAVLSTFYD.RPCGK.CEFEN.Y..........IN...ST.ISDE.D.RN...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------pspgakdatagcinghgpsctemfeesienaeedeggmqdseeddedsysytrtkdesdp..............................
V4A4R8_LOTGI/1-157                  ...............................................ma---------------..----------..-----------...-..--.---K.NRKLQTL....KNDLALENKPDVNFFIIN....G--EHSQEL---.IGRFP.SI....EIPIYQ...-DTEQLGLWRtVFAGN...KDDFIIF..D..RCGRRVYHIPL..PYS.DL...R.LNY...TRYAIDVVYNR.RVCGE.CDSSS.N..........YM...DR.MMGD.Q.P-...............-ASTDVD..EHVDI....VG..Q.SDT...---....-......YR.HR..RR...QR.HGRHQ--.....-----------.....------..----------drdm......................................................................................
W5L435_ASTMX/10-143                 .............................................ilsl---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...---FLFC..A..SCGQLTFHIVL..PYS.YL...H.HPY...VEAAIRATYHR.DIC-N.CTVDS.Ns.......tlSD...EQ.QNST.T.V-...............TTGTSPS..QISEEppadPA..R.PVN...GHH....H......HS.QT..HG...HY.HPTHSHP.....VITKAEDRNIG.....VSHHHT..-HDEGQES--haihkh....................................................................................
G1LAZ4_AILME/4-242                  ................................................g-QSSFCKQPPAWSIR..DQSPMLNSGG..SVTVVALLQAS...S..KY.LLGR.IYRLEDL....RVKLEKEGYLNISYVVVN....HQGLPSQLKYMH.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGK...KDDFLVY..D..RCGRLVHHLGL..PYS.FL...T.FPY...VEEAIKIAYCE.EKCGN.CSLMQ.Ninin..sltqEA...ED.FCKM.V.SS...............ATVGTTT..EAPPP....HH..H.HHH...HHH....-......--.HR..HH...HK.HGHPHHG.....NDELSEDQQPE....aEQAREH..PAPRGLHRHH..........................................................................................
A0A023G9S4_9ACAR/1-127              ................................................m---------------..----------..-----------...-..--.----.-------....---------SDLQFLVVN....DR--HSAHLRGH.LEQRV.SF....AV---H...QESEQEPAWS.ILDGS...KDDVFIF..D..RCGRLSYYVPF..PIS.LV...L.PGYlpvVEDALRRTYEG.TPCGL.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------lcpepadrttratqrhslgwrllhmfsstgepdke.......................................................
SEPP1_RAT/23-248                    ................................................g-QSPACKQAPPWNIG..DQNPMLNSEG..TVTVVALLQAS...U..YL.CLLQ.ASRLEDL....RIKLENQGYFNISYIVVN....HQGSPSQLKHAH.LKKQV.SD....HIAVYR...QDEHQTDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FPY...VEEAIKIAYCE.KRCGN.CSFTS.L..........ED...EA.FCKN.V.SS...............ATASKTT..EP---....--..-.SEE...HNH....-......--.HK..HH...DK.HGHEHLG.....SSKPSENQQPG....aLDVETS..LPPSGLHHHHh.........................................................................................
E9QB63_DANRE/23-254                 ................................................t-EGARCKLPPEWKVG..DVEPMKNALG..QVTVVAYLQAS...C..LF.CLEQ.ASKLNDL....LLKLEKQGYPNIAYMVVN....NREERSQRLHHL.LQERL.L-....NITLYA...QDLSQPDAWQ.AVNAE...KDDILVY..D..RCGRLTYHLSL..PYT.IL...I.HPH...VEEAIKHTYCD.RICGE.CSLES.S..........AQ...LE.ECKK.A.T-...............EEVNKPV..EEEPR....QD..H.GHHeqgHHE....H......QG.EA..ER...HR.HGHHHPHh...hHHHHRGQQQVD.....------..----------vdqqvlsqvdfg..............................................................................
X1YM66_ANODA/533-676                ..........................dernltvypnpltengtfallgl---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.----R...EFQVYVI..D..RCSRVSYIIEP..PWS.LI...Q.FSY...VKAAVLSTFYD.RPCGK.CEFEN.Y..........IN...SS.ISDE.D.R-...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------npspgakdamagcinghapsctemfeesidnaeedeggmqdseeddedsysytrtkdesd..............................
G3NUN5_GASAC/1-216                  .................................................---------------..----------..-----------...-..--.----.---MDGL....RQKLESQGLKDVAYMVVN....QQGEQARRLHPM.LAQRL.SV....NIDLYK...QDEQQPDVWK.TLGGD...KDDFLVY..D..RCGRLTHHIAL..PYS.II...G.QGH...VESAIKDAYCK.RTCGD.CVHES.A..........TT...PE.ECVE.K.AVa............qpDADAPPV..VEDNG....GGggH.HGH...HHH....G......HG.HH..RG...HH.HGHHHGH.....HHGGDHGAGQQavvhqEHERDG..GASHGQH---nsaldqmqqqahipqmphgaqa....................................................................
D6REX5_HUMAN/23-249                 ................................................d-QSSLCKQPPAWSIR..DQDPMLNSNG..SVTVVALLQAS...C..YL.CILQ.ASKLEDL....RVKLKKEGYSNISYIVVN....HQGISSRLKYTH.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGS...KDDFLIY..D..RCGRLVYHLGL..PFS.FL...T.FPY...VEEAIKIAYCE.KKCGN.CSLTT.L..........KD...ED.FCKR.V.SL...............ATVDKTV..ET---....--..-.PSP...HYH....-......--.HE..HH...HN.HGHQHLG.....SSELSENQQPG....aPNAPTH..PAPPGLHHHHkh........................................................................................
B5DDI2_DANRE/1-173                  .................................................---------------..----------..-----------...-..--.----.-------....--------------MVVN....EQDSQSRAMYWE.LKRRT.AQ....DIPVYQ...QSPLQNDVWE.ILEGD...KDDFLVY..D..RCGYLTFHIVL..PFS.FL...H.YPY...IEAAIRATYHK.NMC-N.CSLNA.N..........FS...IS.ESPD.S.TK...............NEPAGEN..NQRPN....ST..E.PVT...AAH....H......HH.HQ..QH...EP.HHHHHNP....yPNSHKKSGDSD....vTGKPKE..PTHHSHQEH-vhnh......................................................................................
F6VJE4_XENTR/25-266                 ................................................t-NSSICKPPPKWSIE..GEVPMAEALG..KVTVVALLQAS...C..GF.CLVQ.AARMGPL....RYKLSLQGMTDIKYMIVN....DQSLHSANMFPE.LKRWA.PE....GIPVYQ...QTPGQDDVWE.LLDGN...KDDFLIY..D..RCGRLTFHVRL..PLS.FL...H.FPY...VEAAILSTYNE.SFCGN.CSFTS.N..........ST...LIpMNGT.T.VSpsgdd.....sssplQNKDEPV..NKEPS....PT..L.EKH...NDQ....R......KL.DSelRL...HD.HSQHHPI.....-NSHKR-QENQ.....NNHPR-..----------nlikngkqn.................................................................................
U3K9A0_FICAL/19-264                 ................................................t-ESQNCQEPPAWRIG..EEDPMWNSRG..SVTVVALLQCS...E..IL.HIFKkSGSLEDL....RVKLENEGLVNISYVVVN....HQGAQSQREFHL.LKERV.SD....YITVYQ...QDEQQEDVWT.TLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...H.FQY...VEESIKIAYCE.NKCGN.CSYTEpD..........ID...IDvVCEN.I.TK...............KAGDELS..EVEPK....LT..G.QHS...HPNp..hR......HG.HH..HR...RH.HHHHHHKg...gRGPRRENLQAA.....PEPERR..HPHSGRRH--glfghhrh..................................................................................
F1RD74_DANRE/28-263                 ................................................s-GSRICKPAPQWEID..GKTPMKELLG..NVVVVALLKAS...C..HF.CLTQ.AARLGDL....RDKLANGGLTNISFMVVN....EQDSQSRAMYWE.LKRRT.AQ....DIPVYQ...QSPLQNDVWE.ILEGD...KDDFLVY..D..RCGYLTFHIVL..PFS.FL...H.YPY...IEAAIRATYHK.NMC-N.CSLNA.N..........FS...IS.ESSD.S.TKne..........pagENNQRPN..STEP-....--..-.-VT...AAH....H......HH.HQ..QH...EP.HHHHNPY.....PNNHKKSGDSD....vTGKPKE..PTHHSHQEH-vhnh......................................................................................
U3JR44_FICAL/27-249                 .................................................NSSRICHEAPAWTIN..GSSPMEGAAG..QVTVVALLK--...-..-F.CLRQ.AHSLGGL....RERLARQGTARVRYMIVN....EKAPLSRAMLPE.LQRHA.PP....GVPVLQ...PEQGDPDVWQ.VLGGD...KDDFLVY..D..RCGRLAFHIQL..PFS.FL...H.FPY...VEAAIRYSHIK.DFCGN.CSFYP.I..........TT...QE.SNST.-.--...............--VEVPA..TPSSF....PE..H.EGM...ESE....T......PI.HQ..HK...PL.HPHHHHE.....---VSSERNTN.....PSENHK..PATHAHHHH-gdh.......................................................................................
V8NYH9_OPHHA/29-180                 .................................................NQTRICQPAPLWKIN..GTEPMAGMEG..Q----------...-..-F.CLKQ.AASLGSL....QEKLSGDGMANVSFMIVN....EKTPSSRAMYWE.LKRHA.PK....GVPVFQ...QQILEPEVWQ.ILQGN...KDDFLIY..D..RCRKLTFHIQL..PYS.FL...H.LPY...VEAAVRYTSRK.DYCGN.CSWYY.L..........NS...S-.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------qev.......................................................................................
H9KP47_APIME/87-182                 ....................................peddtensmeika---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..CCGKITYQIIV..PWS.IL...Y.FPY...VKAAILSTYKD.DPCGP.CYKKI.N..........KN...LD.IRPE.I.FT...............D-ATMPV..EESTR....I-..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------endkytstvipfdsnnyk........................................................................
G3UU18_MELGA/1-166                  .................................................---------------..----------..-----------...-..--.----.-------....--------------MIIN....EQAPLSRAMFGE.LQRHA.PP....GVPVLQ...QQPHEPDVWQ.LLGGD...KDDFLVY..D..RCGRLAFHIQL..PYS.FL...H.LPY...VESAIRFTHRK.DFCGN.CSLYT.N..........ST...QE.ANST.M.--...............---EVPT..TLTPL....PK..Q.EEK...ESE....T......PA.HH..QP...NHlHPHHHAV.....----GSRTAPE.....PSGDHR..PA-HTHHHH-gahgqlh...................................................................................
R4GMT5_HUMAN/23-77                  ................................................d-QSSLCKQPPAWSIR..DQDPMLNSNG..SVTVVALLQAS...C..YL.CILQ.ASKLSKM....K-----------------....------------.-----.--....------...----------.-----...-------..-..-----------..---.--...-.---...-----------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------tfvn......................................................................................
W5PG55_SHEEP/23-207                 ................................................g-QSSYCKQPPAWSIK..DQDPMLNSYG..SVTVVALLQAS...SkhYT.CHQR.YFRLEDL....RVKLEKEGYSNISYVVVN....HQEISSRLKYAH.LKNKV.SE....HIPVYQ...QEEDQPDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FTY...VEDSIKTVYCE.DKCGN.CSLKT.Q..........ED...ED.FCKN.V.SL...............ATKEKTA..EASQR....H-..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------h.........................................................................................
V8PHU7_OPHHA/20-55                  ..............................................ehq---GRCKEPPEWSIE..EENPMMKSRG..TVTVVALLQAS...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-----------..---.--...-.---...-----------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
A0A044QQ64_ONCVO/31-263             .............................................stpi----LCNQTKSWTLD..GQNIVADSKG..FVLLVVLMPMQ...C..EH.CHKQ.LMKFQTI....MET-----LPEIKIVVVA....PYGANSRLIERY.-R-KE.FS....RITI-G...MESLNERIWN.ILSGS...AHDHFIY..D..RCGRLANLIRH..PKS.DA...TkSEH...TLRALKLAVNY.AQCGW.CQYNP.An.......llIS...QK.SIDT.T.YAds...........tlNDKTKKT..FIKAV....IY..R.QND...KRH....K......VN.SD..RQ...HD.IAPDHER.....-----------.....------..----------fslrtntispmrkeyertsddhsnqkm...............................................................
E0CY03_MOUSE/33-110                 ................................................g-QSSACYKAPEWYIG..DQNPMLNSEG..KVTVVALLQAS...C..YL.CLLQ.ASRLEDL....RIKLESQGYFNISYIVVN....HQGSPSQLKH--.-----.--....------...----------.-----...-------..-..-----------..---.--...-.---...-----------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
Q16FG7_AEDAE/94-251                 .........................................ynkinyde---------------..----------..-----------...-..--.---Q.IQLFHNL....FNRFEHNGYRNVQFILGAapsrHPDETEFTEFEDfLDNVT.SVaagyNISVYP...NPLNENGTFA.MFGLK...EFQVYVV..D..RCSRISYIIEP..PWS.LI...Q.YSY...VKAAVLSTMYD.RPCGE.CDVDN.F..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------lnaslpekkldqfimlpalnvteta.................................................................
SEPP1_MOUSE/23-268                  ................................................g-QSSACYKAPEWYIG..DQNPMLNSEG..KVTVVALLQAS...U..YL.CLLQ.ASRLEDL....RIKLESQGYFNISYIVVN....HQGSPSQLKHSH.LKKQV.SE....HIAVYR...QEEDGIDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FPY...VEEAIKIAYCE.ERCGN.CNLTS.L..........ED...ED.FCKT.V.TS...............ATANKTA..EP---....--..-.SEA...HSH....-......--.HK..HH...NK.HGQEHLG.....SSKPSENQQPG.....PSETTL..PP-SGLHHHHrhrgqhrqghlesudttaseglh...................................................................
A0A024R054_HUMAN/72-107             ................................................d-QSSLCKQPPAWSIR..DQDPMLNSNG..SVTVVALLQAS...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-----------..---.--...-.---...-----------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
M3XHZ2_LATCH/1-183                  ................................................m---------------..----------..-----------...-..--.---Q.AARLGSL....HEKFARKGMEDIRYLIVN....NKSPSSRAMFWE.LKRHA.PA....NITVYQ...QAPLQKNVWQ.ILEGK...KDDFFIY..D..RCGKLTFQISL..PFS.FL...N.NSY...VEAAIMSTYHS.DKCGN.CSAANfN..........QT...VQ.VGSN.T.SV..............sAWEESGK..EGLGQ....N-..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------kqsvedyiqhplarldplpslpppphrhlhkrhqrfpeae..................................................
H6WVW6_CAPHI/23-243                 ................................................g-QSSYCKQPPAWSIK..DQDPMLNSYG..SVTVVALLQAS...U..YL.CILQ.ASRLEDL....RVKLEKEGYSNISYVVVN....HQEISSRLKYVH.PKNKV.SE....HIPVYQ...QEDDQPDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FTY...VEDSIKTVYCE.DKCGN.CSLKT.Q..........ED...ED.FCKN.V.SL...............ATKEKTA..EASRR....H-..-.HHH...HRH....-......KG.HQ..RQ...GH.SD-----.....-----------.....------..----------ncdtpvgsenlqlslpqkklurk...................................................................
J0XLE8_LOALO/31-255                 .............................................stpi----LCSQTKPWKLS..GRDIVSDSKG..LVLLVVLMPME...C..EH.CHKQ.LMKFQTV....MET-----LPEIRIVVVA....PHDENPRLIERY.-REEF.P-....RVAI-G...MESLDERIWN.TLSGS...AHDHFIY..D..RCGRLASIIRH..PESdTS...K.FEH...TLWALKLAISY.AQCGW.CQYDP.P..........DL...PS.PHKP.L.VT...............THASSTH..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------kgktkrprikavmypqngrtrmvssdrqadfapdherfssrtntvsparkgharis..................................
Q4RPX4_TETNG/1-182                  .................................................---------------..----------..-----------...-..--.----.---MDSL....RQKLENQGLRDVVYMVVN....HQGAQARGLHAM.LAQRL.SE....HISLHR...QDEALADVWQ.TLGGN...KDDFFIY..D..RCGRLTHRISL..PYA.VI...G.HGH...VEKAVKDTYCS.SLCGE.CTHET.A..........ET...QQ.ECTP.K.T-...............--DTQPQ..ED---....TR..H.ECH...HRH....H......QG.HQ..HHgdgHD.HGHGHHG.....GQGHHQGHDQA.....GGVAQR..P---------adadtda...................................................................................
Q9N0N7_CAPHI/23-205                 ................................................g-QSSYCKQPPAWSIK..DQDPMLNSYG..SVTVVALLQAS...X..YL.CILQ.ASRLEDL....RVKLEKEGYSNISYVVVN....HQEISSRLKYVH.LKNKV.SE....HIPVYQ...QEDDQPDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FTY...VEDSIKTVYCE.DKCGN.CSLKT.Q..........ED...ED.FCKN.V.SL...............ATKEKTA..EASQR....H-..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------h.........................................................................................
R4GJB1_CHICK/1-203                  .................................................---------------..----------..-----------...-..HF.CLLQ.ARSLGAL....RERLGQQGVSDVRYVIVN....EQAPLSRAMFGE.LQRHA.PP....GVPVLQ...QQPHEPDVWQ.LLGGD...KDDFLVY..D..RCGRLAFHIQL..PYS.FL...H.LPY...VESAIRFTHRK.DFCGN.CSLYP.N..........ST...QE.ANST.M.E-...............----VPA..TLTPL....PK..Q.EEK...ESE....T......PA.HH..-Q...PN.HLHPHHR.....--AVGNGTAPE.....PSGDHR..PA-HAHHHH-gahgklhpkgqtpegrd.........................................................................
J9NST4_CANFA/1-138                  ................................................m---------------..----------..-----------...-..--.----.-------....------------------....-----------Y.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGK...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FPY...VEEAIKRAYCE.EKCGN.CSLTV.L..........ED...EE.VCKM.V.SS...............GTVESTT..EAPQP....HP..H.DHH...LH-....-......--.-H..HH...HH.HHHKHHD.....-----------.....------..----------kftstyqafkalkch...........................................................................
G3TLW1_LOXAF/23-207                 ................................................v-QSSFCKQPPAWKIR..EEDPMLNSIG..SVTVVALLQAS...RknYT.CLQR.TCQLEDL....RVKLEKEGYSNVSYVIVN....HQDLNSRLKYIH.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FPY...VEAAIKIVYCE.EKCGN.CSLMT.P..........ED...ED.FCKK.V.SS...............VNVEDTA..EASKP....H-..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------h.........................................................................................
F4X476_ACREC/858-966                ..............................................itl---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-CGMLTYHVIV..PWS.IL...F.FPY...VKAAILSTYMD.DPCGE.CNPAV.Y..........RA...SN.HEDH.V.VE...............LTKSTKK..ELNPS....YR..E.VDT...KFEi..iW......TT.ES..LP...EN.LTHLHYE.....-----------.....------..----------ssseeeretsiassi...........................................................................
A6FZW7_9DELT/137-264                .......................cpecapiwdlydfqpqscgytetygl---------------..-----DSFEG..HVTLIAMLAGW...C..SY.CQSQ.AGKMEEM....RLELALEGY-DVQMIAIN....ATSADNDDDRQN.LVDRC.A-....-FPLF-...QDIDEVDAWD.LHGGT...KDDLVIY..H..ADGTMA-----..---.--...-.---...-----------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------vfld......................................................................................
V5H5E6_IXORI/1-200                  .................................................---------------..----------..-----------...-..--.----.---LEAL....LLKLRARNLSDVQFLVVN....SLD--SAAEVRE.LERRV.S-....-FPVYQ...-ETANELVWS.VLEGD...KDDVFIY..D..RCGRLSYFIPF..PLS.VTlpgR.HPV...VEEALNTTYYA.SPCGD.FCPQD.S..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------saiplgssphehqqqripgqidaegegetgiavsppatpseglgwrvihmvfgdghqgqvdshtpsraqeggvtrgaphdhqerhptpte
H2UNP3_TAKRU/23-253                 ................................................g-DGPRCQLPPVWKIG..DLEPMKEAMG..RVTVVALLESS...W..LS.DFLH.LGRMDSL....RQRLENQGLRDVVYMVVS....HQGAHAPGLHAM.LAQKL.TE....HISLYK...QDEALPDVWQ.TLGGN...NNDFFIY..D..RCGRLTHRISL..PYS.II...G.HGH...VERAVKDTYCN.SLCGE.CTHET.T..........ET...LQ.ECTP.K.TS...............ALPDNGV..APGAE....E-..-.TGH...ECH....H......HG.RQ..HH...GD.GHRDHGD.....-SQCTHTRGSG.....RGHGHH..HGHGGQGQH-eg........................................................................................
K7FTE4_PELSI/15-167                 ................................................n-KTRICQPAPQWAIN..GTAPMKRELG..RVTVVALLKAS...-..QF.CLKQ.AHSLGGL....RAKLSRDGLTDISYMIVN....EKAALSRAMYWQ.LKRQA.PK....GVPVYQ...QELLEPDVWQ.ILDGD...KDDFLIY..D..RCGRLAFHIPL..PYS.FL...H.LRY...VESAVRVTHAK.DFCGN.CS---.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
H3DGX7_TETNG/23-251                 ................................................g-DGPRCQLPPTWKIG..DLEPMTGAMG..RVTVVALLDAR...S..TI.DFLN.LGRMDSL....RQKLENQGLRDVVYMVVN....HQGAQARGLHAM.LAQRL.SE....HISLHR...QDEALADVWQ.TLGGN...KDDFFIY..D..RCGRLTHRISL..PYA.VI...G.HGH...VEKAVKDTYCS.SLCGE.CTHET.A..........ET...QQ.ECTP.K.T-...............--DTQPQ..ED---....TR..H.ECH...HRH....H......QG.HQ..HH...GD.GHRDHGD.....-NQCTHTQGSG.....PGHDHG..HGHHGGQGHHqgh.......................................................................................
G5APA7_HETGA/37-233                 ...................................plvklneiihlmhf---------------..----------..-----------...-..--.-FPK.YLRFEDL....RVKLEKEGYSNISFVIVN....HQGSNSRLKYIQ.LKNQV.SD....HIPVYQ...QEEHQTDVWS.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...S.FPY...VEEAIKIAYCE.EKCGN.CSLRT.L..........ED...ED.FCKN.V.SL...............ATVEKTA..EA---....--..-.--P...HPH....-......--.NK..QH...HK.HGHQHLG.....GSELSDNKQPE....aPDNPVL..S-PLGHHHHHe.........................................................................................
Q9BDE4_BOVIN/1-126                  .................................................---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FTY...VEDSIKTVYCE.DKCGN.CSLSR.P..........QD...ED.VCKN.V.FL...............ATKEKTA..EASQR....HH..H.PHP...HPH....P......HP.HP..HP...HH.GH-QLHE.....NAHLSESPKPD....tPDTPEN..PPTSGLHHHHh.........................................................................................
M4ANC2_XIPMA/23-205                 ................................................g-GGPRCQPPPTWMIG..EVEPMKGTAG..QVTVVALLQAT...L..RL.QILS.NQRIDGL....RQKLETQGLNDVVYMVIN....HQGEQAQRLHPL.LAQRL.SD....KISLYK...QGEQQPDVWQ.TLNGK...KDDFIIY..DslRCGRLTDHISL..PYS.VI...G.HGH...IESAIKEAYCN.RKCGA.CSHET.A..........ET...PE.ECRA.T.PN...............AQ-----..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------pdadtpaavg................................................................................
F1N9T1_CHICK/1-159                  .................................................---------------..----------..-----------...-..-L.CLLQ.ASRLEDL....RVKLENEGLVNISYVVVN....HQSPHSQKKFHL.LQESV.SD....HITVYQ...QDDHQADVWT.TLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...S.FQY...VEEAIKIAYCE.NNCGN.CSYTE.P..........DI...DN.ICEN.I.TK...............K---EGI..EPEPE....PS..G.QHS...HHH....H......QL.HR..HR...HH.H------.....-----------.....------..----------..........................................................................................
E0CZC5_MOUSE/23-177                 ................................................g-QSSACYKAPEWYIG..DQNPMLNSEG..KVTVVALLQAS...C..YL.CLLQ.ASRLEDL....RIKLESQGYFNISYIVVN....HQGSPSQLKHSH.LKKQV.SE....HIAVYR...QEEDGIDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FPY...VEEAIKIAYCE.ERCGN.CNL--.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
I6SJ59_BUBBU/23-264                 ................................................g-QSSYCKQPPPWSIK..DQEPMLNSYG..SVTVVALLQAS...U..YL.CILQ.ASRLEDL....RVKLEKEGYSNVSYVVVN....HQGIVSRLKYVH.LKNKV.SE....HIPVYQ...QEENQPDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FTY...VEDSIKTVYCE.DKCGN.CSLKA.L..........ED...ED.VCKN.V.FL...............ATKEKTA..EASQR....HH..H.PHP...HSHp..hP......HP.HP..HP...HP.HPHSHHGhqlheNAHLSESPKPD....tPDTPEN..PPPSGLHHHHh.........................................................................................
H3CE96_TETNG/6-134                  .......lfmvylrsgmwslliyciywhlklglsdevdnceslhlgqyl---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-----------..---.--...-.---...-----------.--CNE.PRIDEaT..........QE...PE.NCKD.M.IA...............WGETRSR..SKNQK....TH..EdTHT...HTH....T......HT.HT..HT...HT.HTHTHTH....tHQPVNLQLHTSt...nSQAKQH..----------palgyrcr..................................................................................
D2XNK7_SACKO/23-265                 ................................................i--SPECPDGVLWSVN..EETPMLANRG..KVVVVALLQAS...U..HF.CLSQ.AEALEVL....REKFLSQGMDEISFLVVN....SKKLHSQFLIGH.LHQRV.S-....-FPVYQ...A-RYENDIWS.QLDGA...KDDIIVY..D..RCGKLVDHIRM..PYS.FL...E.NDN...VERAIVSAYYE.NPCGR.CEVVEpQ..........VS...ED.LVTY.E.VNt............syEGSGDII..DGDPL....VY..L.IEL...EHEv.edL......EK.QA..LE...RQ.RVRNHSQ.....TNSSDESQMVG.....QDEKNS..ESMESR----edksgsassee...............................................................................
G1Q9G6_MYOLU/23-202                 ................................................g-QSPFCKPPPAWITL..VYVFIRYPH-..--STASLLKKT...Y..YF.CLRQ.ASSLEDL....RVKLEKEGFSNISYVVVN....HQGHPSRLRYNL.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PFS.IL...E.FPY...VEQAIKIAYCE.EKCGN.CSLTT.L..........ED...ED.FCKN.M.SL...............ATVRKTT..EASEP....H-..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------h.........................................................................................
I3JR88_ORENI/1-180                  .................................................---------------..----------..-----------...-..--.----.-------....--------------IIVN....ERDAHSRAMYWE.LKRSA.PT....GVPVFQ...QQPFQNDVWE.ALDGD...KDDFLVY..D..RCGLLTFHIVM..PYS.FL...H.HPF...VEAAIRATYQK.NIC-N.CTQNF.T..........SSvggNN.ITNN.G.TA...............QLVDEGS..EVPDT....AS..G.RTH...HHH....H......HH.HH..HD...DP.PSHHHHH.....-DQHSSHQNQS.....LHQQDQ..GDSTSHHHHHsphqqhqhdh................................................................................
D6RIS9_HUMAN/23-209                 ................................................d-QSSLCKQPPAWSIR..DQDPMLNSNG..SVTVVALLQAS...C..YL.CILQ.ASKLEDL....RVKLKKEGYSNISYIVVN....HQGISSRLKYTH.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGS...KDDFLIY..D..RCGRLVYHLGL..PFS.FL...T.FPY...VEEAIKIAYCE.KKCGN.CSLTT.L..........KD...ED.FCKR.V.SL...............ATVDKTV..ETPSP....HY..H.HE-...---....-......--.--..--...--.-------.....-----------.....------..----------h.........................................................................................
W5KEM0_ASTMX/23-259                 ................................................g-DGARCKPPAVWKIG..DVEPLKDSLG..QVTVVAFLQKT...K.wVL.DDLT.LDRLDSL....RLKLEKAGYANITYLVVN....SQDENSRRLHSL.LEQRL.SA....NITLYG...QEPDAQDIWQ.IANVM...KDDFQIY..D..RCGRLTHHLSL..PYT.IL...S.GPH...VEEAIRNTYCD.RTCGE.CSMES.S..........IQ...PQ.ECNG.T.V-...............--EEKPV..VEEEE....VG..R.GHHg.gGHHs..gH......HG.GH..HG...GH.HGGHHGG.....HHGGHHSGHHG.....HHGDHG..GQQRGHHDQHtd........................................................................................
G9KN32_MUSPF/1-156                  .................................................---------------..----------..-----------...-..-L.CILQ.ASRLEDL....RVKLEKEGYLNISYVVVN....HQGLSSQLQYMN.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGK...KDDFLIY..D..RCGRLVYHLGL..PYS.FL...T.FPY...VEEAIKIAYCE.EKCGN.CSLTT.L..........EA...KD.FCEM.V.SS...............PTVGNTT..EAPQP....HH..H.HHH...HHH....-......-L.HH..H-...--.-------.....-----------.....------..----------..........................................................................................
SEPP1_HUMAN/23-249                  ................................................d-QSSLCKQPPAWSIR..DQDPMLNSNG..SVTVVALLQAS...U..YL.CILQ.ASKLEDL....RVKLKKEGYSNISYIVVN....HQGISSRLKYTH.LKNKV.SE....HIPVYQ...QEENQTDVWT.LLNGS...KDDFLIY..D..RCGRLVYHLGL..PFS.FL...T.FPY...VEEAIKIAYCE.KKCGN.CSLTT.L..........KD...ED.FCKR.V.SL...............ATVDKTV..ET---....--..-.PSP...HYH....-......--.HE..HH...HN.HGHQHLG.....SSELSENQQPG....aPNAPTH..PAPPGLHHHHkh........................................................................................
M1EV50_MELGA/1-100                  .................................................---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-----------..---.--...-.---...-----------.-----.CSYTE.P..........DV...DY.ICEN.I.TK...............KEDENLAgiEPESE....PS..G.QHS...HHH....H......QV.PR..HR...HH.HHHHHHR....eGGRHSKNQNHQ....aPSESQR.rHPHNGRRQ--rvfnhnrhdqigshdq..........................................................................
Q5PR33_DANRE/28-263                 ................................................n-GSRICKPAPQWEID..GKTPMKELLG..NVVVVALLKAS...U..HF.CLTQ.AARLGDL....RDKLANGGLTNISFMVVN....EQDSQSRAMYWE.LKRRT.AQ....DIPVYQ...QSPLQNDVWE.ILEGD...KDDFLVY..D..RCGYLTFHIVL..PFS.FL...H.YPY...IEAAIRATYHK.NMC-N.CSLNA.N..........FS...IS.ESPD.S.TK...............NEPAGEN..NQRPN....ST..E.PVT...AAH....H......HH.HQ..QH...EP.HHHHHNP....yPNSHKKSGDSD....vTGKPKE..PTHHSHQEH-vhn.......................................................................................
I3LJP2_PIG/5-135                    ..............................................yyy---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-----YY..F..RCGLLVYHLGL..PYS.FL...T.FPY...VEEAIKTVYCE.NKCGN.CSLKT.L..........KD...ED.FCKN.V.YL...............ATEEKTT..EAPQP....HH..H.HDH...HHH....-......--.RH..HH...HH.HGHQHLG.....NGHLSEHPKPE....aPDTPEQ..PPPSGLHHHHghkghqrqgh................................................................................
H2MB78_ORYLA/1-159                  .................................................---------------..----------..-----------...-..--.----.-------....--------------MIVN....ELEALSQTMHWK.LKKKA.PT....GVPVYQ...QSSLQKDVWE.ILDGD...KDDFLIY..D..RCGLLTFHIVL..PNS.FL...Q.NAD...VENAITATYTQ.DIC-N.CSGNS.TlsgggnnftrN-...SS.----.-.-Qshsgvq...rpadepENVTTTL..EASPN....DS..R.HEH...AHH....H......HP.HH..QH...LH.HHHPHHQ.....-----------.....------..----------hlh.......................................................................................
K7E6A4_MONDO/1-186                  .................................................---------------..----------..-----------...-..--.----.---MGSL....QERLARMGAPDVRFIIVN....EKSPQSRALHGE.LELHA.PP....GVPVYG...QPELGPDIWS.ILGGA...KDDFLIY..D..RCGRLTFHIRL..PFS.FL...H.FPY...VESAIRFTHRQ.DSCGN.CSFYP.A..........QV...NS.TDER.K.GEskhs.......pgleG------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------egqeplgekpdsrgltlgssaptahahdpvhggmekpspslpspalepslhege....................................
K7JYM3_NASVI/162-308                ...........................................lgpdvy---------------..----------..-----------...-..--.----.-------....------------------....------------.-----.--....----FI...QDNDELQIWS.KLRAF...RDQILVI..D..RCGRLTYQVIV..PWS.IL...H.FPY...VKAAILSTYKD.EPCGY.CQFKE.T..........VF...DT.TSTDnK.DA...............QSSSKLV..EQTED....ND..N.P--...---....-......--.--..--...--.-------.....-----------.....------..----------stlsqetttviyeaesydttltvdessspivqtehevtslstsdrn............................................
SELPB_DANRE/28-263                  ................................................n-GSRICKPAPQWEID..GKTPMKELLG..NVVVVALLKAS...U..HF.CLTQ.AARLGDL....RDKLANGGLTNISFMVVN....EQDSQSRAMYWE.LKRRT.AQ....DIPVYQ...QSPLQNDVWE.ILEGD...KDDFLVY..D..RCGYLTFHIVL..PFS.FL...H.YPY...IEAAIRATYHK.NMC-N.CSLNA.N..........FS...IS.ESSD.S.TK...............NDPAGEN..NQRPN....ST..E.PVT...AAH....H......HH.HQ..QH...EP.HHHHHNP....yPNSHKKSGDSD....vTGKPKE..PPHHSHQEH-vhn.......................................................................................
I3KDC0_ORENI/1-102                  ................................................l---------------..----------..-----------...-..-F.CLVQaSSRLDGL....QQKLERQGLKNVVYMVVN....HQGEQSRHLHPL.LEAKL.SK....NIILYK...QDGHQPDVWQ.TLAGE...KDDFFIY..D..RCGRLTYRISL..PYS.II...G.EGH...IE---------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
H2ZVW4_LATCH/23-227                 ................................................g-KSTRCKEPPTWYIG..EENPMLESRG..KVTVVALLQAS...S..FY.IILY.VSRMDDL....HLKLENEGLVNISYMIVN....HQGEYSQHKHNL.LKQRV.SE....FIPVYK...QDMEKPNVWN.LLNGN...KDDFLIY..D..RCGRLVYHLGL..PYS.VL...H.FPY...MEEAIRIAFCE.TRCGN.CSFTV.K..........DI...NE.ICNR.T.E-...............-NTDEPV..EEPPP....TS..V.PDP...PQQnpqhH......GA.HR..HH...RQ.HGH----.....-----------.....------..----------q.........................................................................................
K7F0S1_PELSI/23-58                  ................................................g-SSARCKEPPEWKIG..EHSPMLNSRG..SVTVVALLQAS...-..--.----.-------....------------------....------------.-----.--....------...----------.-----...-------..-..-----------..---.--...-.---...-----------.-----.-----.-..........--...--.----.-.--...............-------..-----....--..-.---...---....-......--.--..--...--.-------.....-----------.....------..----------..........................................................................................
#=GC seq_cons                       ..........................................................................................................ht.l....h.ph...th.sltahlVN....ppt..uphhh...Lppph.s.....tlslYp...Q-..p.clWp.hLsGs...KDDFlIY..D..RCGRLsaHlsL..PaS.hL...p.asY...VEtAI+hsYpc.phCGs.Cohps............pt....p..spt.......................t.....t...............................................................................................t.........................................................................................
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