GenomeNet

Database: Pfam
Entry: Serglycin
LinkDB: Serglycin
Original site: Serglycin 
#=GF ID   Serglycin
#=GF AC   PF04360.10
#=GF DE   Serglycin 
#=GF AU   Finn RD
#=GF SE   DOMO:DM07201;
#=GF GA   30.00 30.00;
#=GF TC   30.10 30.10;
#=GF NC   28.90 29.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   2261494
#=GF RT   Proteoglycans in haemopoietic cells. 
#=GF RA   Kolset SO, Gallagher JT; 
#=GF RL   Biochim Biophys Acta 1990;1032:191-211.
#=GF DR   INTERPRO; IPR007455;
#=GF CC   Serglycin is the most prevalent proteoglycan produced in
#=GF CC   haemopoietic cells. Serglycin is a proteinase resistant
#=GF CC   secretory granule  proteoglycan [1].
#=GF SQ   45
#=GS F6TAL8_ORNAN/3-134      AC F6TAL8.1
#=GS B8A5H9_DANRE/1-98       AC B8A5H9.1
#=GS U3KF30_FICAL/1-84       AC U3KF30.1
#=GS W5KQN2_ASTMX/1-107      AC W5KQN2.1
#=GS G1PL01_MYOLU/2-144      AC G1PL01.1
#=GS E0CYA5_MOUSE/1-27       AC E0CYA5.1
#=GS SRGN_RAT/119-177        AC P04917.1
#=GS R0KFX7_ANAPL/1-77       AC R0KFX7.1
#=GS G3VMB2_SARHA/4-142      AC G3VMB2.1
#=GS F6WU42_HORSE/2-148      AC F6WU42.1
#=GS G5B180_HETGA/2-154      AC G5B180.1
#=GS F6V440_CANLF/3-154      AC F6V440.1
#=GS G1MHZ0_AILME/3-149      AC G1MHZ0.1
#=GS G1TRF0_RABIT/3-153      AC G1TRF0.1
#=GS A0A091EMS8_FUKDA/2-158  AC A0A091EMS8.1
#=GS H0V4Q4_CAVPO/3-149      AC H0V4Q4.1
#=GS F6Z655_MACMU/3-149      AC F6Z655.1
#=GS G1RLG0_NOMLE/3-149      AC G1RLG0.1
#=GS M3XAA0_FELCA/2-156      AC M3XAA0.1
#=GS G3VMB1_SARHA/9-148      AC G3VMB1.1
#=GS K7ETL7_PONAB/3-110      AC K7ETL7.1
#=GS G3QLB2_GORGO/3-153      AC G3QLB2.1
#=GS G7PF56_MACFA/2-145      AC G7PF56.1
#=GS H2NAQ2_PONAB/3-151      AC H2NAQ2.1
#=GS A0A096P500_PAPAN/3-146  AC A0A096P500.1
#=GS G5E5K5_BOVIN/2-143      AC G5E5K5.1
#=GS B8A5I0_DANRE/1-72       AC B8A5I0.1
#=GS K7ETL7_PONAB/104-161    AC K7ETL7.1
#=GS SRGN_RAT/2-107          AC P04917.1
#=GS SRGN_MOUSE/1-149        AC P13609.1
#=GS L5KGF5_PTEAL/2-140      AC L5KGF5.1
#=GS W5P5K9_SHEEP/3-144      AC W5P5K9.1
#=GS G1MPG2_AILME/5-147      AC G1MPG2.1
#=GS L5M275_MYODS/2-148      AC L5M275.1
#=GS SRGN_HUMAN/3-151        AC P10124.3
#=GS H0WT33_OTOGA/3-149      AC H0WT33.1
#=GS F1P2B0_CHICK/25-122     AC F1P2B0.1
#=GS H2Q202_PANTR/3-155      AC H2Q202.1
#=GS H0Z0A1_TAEGU/1-83       AC H0Z0A1.1
#=GS I3LKI1_PIG/4-147        AC I3LKI1.1
#=GS S9X855_9CETA/2-146      AC S9X855.1
#=GS A0A0D9R614_CHLSB/3-146  AC A0A0D9R614.1
#=GS L9KSG6_TUPCH/3-151      AC L9KSG6.1
#=GS G3STW9_LOXAF/1-151      AC G3STW9.1
#=GS F7HD78_CALJA/3-151      AC F7HD78.1
F6TAL8_ORNAN/3-134                 ..kiypaaeki----------FAPVLLC.ALLSSVsAGVPV..QKARYKWVRCNPDGNSANCIEEKGPLFEIRDGDAN....KILPPRT.D.PYLTKKLQDLNEIFPLSEDE.......eSGSGNDF....SSGMEPEPG-------------..-----------------------------sgveyfeplalklpsdkqdfgqel
B8A5H9_DANRE/1-98                  ......mrfyh-------MITLALAIIC.LSGHSG.LGAPAasTKGNYMWVECKPDGKNANCLTKKGPLIPLD-GQRT....RLPPSAA.K.DIVAVSAE---EATPDTEDL........SGDGSG-....----------------------..-----------------------------dsdnf...................
U3KF30_FICAL/1-84                  ...........-----------------.------.-GAPM..QRARYKRVRCRPDAWSANCIEEKGPWFYMPAGGAN....RILPPMA.D.PSLMKRYQELGDIFPLSDED........SGSGSS-....----------------------..-----------------------------tvveaepasgs.............
W5KQN2_ASTMX/1-107                 ........mrf-----YQRIAFVLLLVY.LFEDNV.LGAPA..Q-GRYNWVTCKPDSKNANCIQKQGPLIDIS-GASQ....RLPPSATkD.IVPVERDEDTPE--TETEEQ........SGESSG-....----------------------..-----------------------------dldlaekkqdwmddg.........
G1PL01_MYOLU/2-144                 ...........QVLLPRSRLVLALALIL.TLDSSV.QGLPV..RRARYQRVRCNPDSTSANCIEEKGPLFDLLPGESN....RILPPRT.D.PFLMMRFQNLNDVFPLSEDD........----SGS....GSGSGSGSGNGFLTGTESEYQPsfVDTNDAFYYNFKP----VPTDDQDLGQDG........................
E0CYA5_MOUSE/1-27                  .........mq--VPVGSRLVLALAFVL.VWGSSV.QGYP-..-----------------------------------....-------.-.--------------------........-------....----------------------..-----------------------------........................
SRGN_RAT/119-177                   ..........g-----------------.------.-----..-----------------------------------....-------.-.--------------------........SGSGSGS....GSGSGSGSGSGSLADMEWEYQP..TDENNIVYFNYGPFDRMLTEQNQEQPGD-f.......................
R0KFX7_ANAPL/1-77                  ...........-----------------.------.-GAPV..QKARYKRVRCRPDAWSPNCIEEKAPWL-LPHGGANxxxxRILPPVA.D.PSPMKSDQ-MSDIFPLSEEE........SGSGL--....----------------------..-----------------------------dtt.....................
G3VMB2_SARHA/4-142                 .tllkldwqih-----------SMSLIM.CGHFIC.SGFPA..RRARYHWVRCRPDSLSANCIEEKGPWFNMPEGEDN....GIVSPPM.D.PYLIKRPRDMVEKFPFSEED........PWSISGS....GSGSGSGSGSS--AEVE--TEP..IDEED--FYNFRSSDD-------------envgqeltee..............
F6WU42_HORSE/2-148                 ...........QVLLQGSRLVLALTLIL.VLSSSV.QGFPV..QRARYQWVRCSPDSNSANCIDERGPVFDLLPDEPN....RILPPRT.D.PFSMTRSQNLNDVFPLSEDY........--SGSGF....GSGSGSGSESSFLTDIEQEYQP..ADENNAFLYNFRSLKGNLPSDNQDLGQDG........................
G5B180_HETGA/2-154                 ...........QAVLTCGRLVLALTLIL.VLGSAV.EGYPM..RKARYQWVRCNPHSNSANCIEEKGPLFDLPTDESN....RILPPKA.D.PYLMPKFPNLNDVFPLSEDYsg....sgSGSGSGS....GSGSGSGSGKEYSTEMERDYQP..IDENDVFYYNFRSLKKNLPSDNQALGQDG........................
F6V440_CANLF/3-154                 ...........QLLLQGSRLVLALALLL.VLDFSV.QGSPV..KRATYQWVHCSPDSNSANCIDEKEPMFDLLPGESN....RIFPPTD.RsSFRMSRSQNLNDIFPISEDYf......gSGSGSGS....GSGSGSGSGSGFLPELEQEYQP..VDENNDFYDNFRPLKRNLPSDNQDLGQDG........................
G1MHZ0_AILME/3-149                 ........qlp---QQGSRLVLALALLL.VLDSPV.QGSPV..RKAKFQWVRCSPDSNSANCIDEKGPMFNLLPGESN....RILPPRT.D.PSSMTRSQNWNDVFPLSEDY........SGSGF--....GSGSESGSGSGFLTEIEQEYQP..VDENSAFYYNFRPLKRNLPSDNQDLVQDG........................
G1TRF0_RABIT/3-153                 ...........QKLLTCSGLVLALGLIL.TLDSSV.QGYPM..RRARYQWVRCRPDSNSANCIDEKGPVFNLLPGDSN....RILPLRT.D.PFFRTGPQRLNDAFPLSEDV........SGSGSGSd..lGSGSGSGSGSSLPTEVEWEYQP..VQEDGVFYHNSEPLERNLPSASQDLGHGG........................
A0A091EMS8_FUKDA/2-158             ...........QAVLTCGRLALALALVL.VLGSTV.QGYPM..RKARYQWVRCNPDSNSANCIEEKGPLFDLSTDESN....RILPPKV.D.PFLMPKFPNLNDVFPLSEDYfgsgsgsgSGSGSGS....GSGSGSGSGKEYPTEMEWDYQP..IDENDVFYYNFRSLKKDLPSDNQALGQDG........................
H0V4Q4_CAVPO/3-149                 ...........QALPTCGRLGLALVLIL.ALGSSV.QGYPM..RKARYQWVHCSPDSNSANCIEEKGPVFDLPTDDYN....EILPSKT.D.PFLIRKRQNLNDIFPLSEDY........--SESGS....GSGFGSSSEKDYPAERQWDYQP..LDEKDAFYYNLRPLRKNLPLDNQALGQD-d.......................
F6Z655_MACMU/3-149                 ...........QKLLKCSRLVLALALIL.VLESSV.QGKTQ..ESSRYQWVRCNPDSNSANCIEEKGPMFDLLPSESN....KIPRLRT.D.LFPKTRIQDLNRIFPLSEDY........--SGSGS....GSGSGSGSGSGFVTEMEQDYQP..VDESDAFHDNLRSLDRNLPSDSQDLGQHG........................
G1RLG0_NOMLE/3-149                 ...........QKLLKCSWLVLALALIL.VLESSV.QGYPM..QRARYQWVRCNPDSNSANCLEEKGPMFELLPGESN....KISRLRT.D.LFPKTRIQDLNRIFPLSEDY........--SGSGS....GSGSGSGSGNGFLTEMEQDYQL..VDESDAFHDNLRSLDRNLPSDSQDLGQHG........................
M3XAA0_FELCA/2-156                 ...........QRLLQGTTFVLALALLL.VFDSSV.QGSPV..RRARYQWVRCNPESNSANCIDEKGPMFNLLPDETN....RILPPRT.D.PLLMTGSQNLNDVFPLSEDYfgs..gsgSGSGSGS....GSGSGSGSGSGLLTEIDQEYQP..VDENDAFYYNFRPLKRNLPSDNQDLGQDG........................
G3VMB1_SARHA/9-148                 .......hlwm----HPRRILLALSLLL.FMESLV.QGFPA..RRARYHWVRCRPDSLSANCIEEKGPWFNMPEGEDN....GIVSPPM.D.PYLIKRPRDMVEKFPFSEED........PWSISGS....GSGSGSGSGSS--AEVE--TEP..IDEED--FYNFRSSDD-------------envgqeltee..............
K7ETL7_PONAB/3-110                 ...........QKLLKCSRLVLALALIL.VLESSV.QGYPT..QRARYQWVRCNPDSNSANCLEEKGPMFELLPGESN....KIPRLRT.D.LFPKTRIQDLNRIFPLSEDY........SGSGSGS....GSGSGSGSGS------------..-----------------------------........................
G3QLB2_GORGO/3-153                 ...........QKLLKCSRLVLALALIL.VLESSV.QGYPT..QRARYQWVRCNPDSNSANCLEEKGPMFELLPGESN....KIPRLRT.D.LFPKTRIQDLNRIFPLSEDYs......gSGSGSGS....GSGSGSGSGSGFLTEMEQDYQL..VDESDAFHDNLRSLDRNLPSDSQDLGQHG........................
G7PF56_MACFA/2-145                 ...........QKLLKCSRLVLALALIL.VLESSV.QGYP-..--ARYQWVRCNPDSNSANCIEEKGPMFDLLPSESN....KIPRLRT.D.LFPKTRIQDLNRIFPLSEDY........--SGSGS....GSGSGSGSGSGFVTEMEQDYQP..VDESDAFHDNLRSLDRNLPSDSQDLGQHG........................
H2NAQ2_PONAB/3-151                 ...........QKLLKCSRLVLALALIL.VLESSV.QGYPT..QRARYQWVRCNPDSNSANCLEEKGPMFELLPGESN....KIPRLRT.D.LFPKTRIQDLNRIFPLSEDY........SGSGSGS....GSGSGSGSGSGFLREMEQDYQL..VDESDAFHENLRSLDRNLPSDSQDLGQHG........................
A0A096P500_PAPAN/3-146             ...........QKLLKCSRLVLALALIL.VLESSV.QGYP-..--ARYQWVRCNPDSNSANCVEEKGPMFDLLPSESN....KIPRLRT.D.LFPKTRIQDLNRIFPLSEDY........--SGSGS....GSGSGSGSGSGFLTEMEQDYQP..VDESDAFHDNLRSLDRNLSSDSQDLGQHG........................
G5E5K5_BOVIN/2-143                 ...........QVLLQCARLVLALAFIL.-FSSSV.QGSPV..QRAGYQCNPDSPDSNSANCIEEKGTAFDILRGESS....RIPPPRT.D.ISPLMNSKNLNEVFPLSEDI........------S....GSGSGAESGSGFLNEIEQEYQP..VEENDAFYYTFRSRKRNVPSYNQDLGQDG........................
B8A5I0_DANRE/1-72                  ......mrfyh-------MITLALAIIC.LSGHSG.LGAPAasTKGNYMWVECKPDGKNANCLTKKGPLIPLD-GQRT....RLPPS--.-.--------------------........-------....----------------------..-----------------------------aakdm...................
K7ETL7_PONAB/104-161               ...........-----------------.------.-----..-----------------------------------....-------.-.--------------------........SGSGSGS....GSGSGSGSGSGFLREMEQDYQL..VDESDAFHENLRSLDRNLPSDSQDLGQHG........................
SRGN_RAT/2-107                     .........rq--VPVGTRLVLALAFVL.VWGSSV.QGYPA..RRARYQWVRCKPDGIFANCIEEKGPRFDLIAEESN....-VGPPMT.D.PVLMRGFPN--DFFPISDDY........SGSGSGS....GSGSGSGSGSG-----------..-----------------------------........................
SRGN_MOUSE/1-149                   .........mq--VPVGSRLVLALAFVL.VWGSSV.QGYPA..RRARYQWVRCKPNGFFANCIEEKGPQFDLI-DESN....NIGPPMN.N.PVLMEGPSK--DFISNYDDYg.....sgSGSGSGS....GSGSGSGSGSGFLGDMEWEYQP..TDESNIVYFNYKPFDRILTEQNQDQPED-d.......................
L5KGF5_PTEAL/2-140                 ...........QVLLQCRRLVLALILIL.VLDSSV.QGSPV..RRARYQWVRCNPDSNSINCVDEKGPEFDLPPGESN....RILSPRT.D.PFSMTIPQNLNDVFPLSEDY........------S....GSGSGSDSGSGFSTETEQEYQP..ADKDDAFYYNFRP----LPSDDQDLGRDG........................
W5P5K9_SHEEP/3-144                 ...........QVLLQCTRLALALAFIL.-ISSSV.QGSPV..QRARYQWVRCNPDSNSANCVQEKGRVLDILPDESS....RIPPLRS.D.IFLLENSRDLNEVFPLSEDV........------S....GSGSGAGSENGFLNEIEQEYQP..VEENDAFYYNFRSKEGNAPSYNQDLGQDG........................
G1MPG2_AILME/5-147                 ........qav-----TMRLLLALALLL.GLDSSV.QGCPV..RRAGYQWLGRSPDGNFASCIDEKGLTFSLLPGESN....RILPPRT.D.PASMTRSQNLNGVFPLSESY........----FGS....GSGSGSGSRSGFFTEIEQEYQA..VDENNAFYYNFRPLKRNRPSDSRDLGQDG........................
L5M275_MYODS/2-148                 ...........QVLLPYSRLGLALALIL.TLDSSV.QGLPV..RRARYQRVRCNPDSTSANCIDEKGPLFDLLPGESN....RILPPRT.D.PFLMMPFQNLNDVFPLSEDY........SGSGSGS....GSGSGSGSGDDFLTGMESEYQPsfVDTNDAFYYNFKP----VPTDDQDLGQDG........................
SRGN_HUMAN/3-151                   ...........QKLLKCSRLVLALALIL.VLESSV.QGYPT..RRARYQWVRCNPDSNSANCLEEKGPMFELLPGESN....KIPRLRT.D.LFPKTRIQDLNRIFPLSEDY........SGSGFGS....GSGSGSGSGSGFLTEMEQDYQL..VDESDAFHDNLRSLDRNLPSDSQDLGQHG........................
H0WT33_OTOGA/3-149                 ...........QWLLKCRGLVLAFALIL.VLGSSV.QGYPM..RRARYQWVRCNPNSNSANCIDEKGPMFDLVPDESN....RILPPRT.D.PFSMTRLQNWNDIFPLSEDD........--SGSGS....GSGSGSGSGSGFLTEMEQEYQP..VDESDAFYYNSRSLDRNLPSDNQDLGEDG........................
F1P2B0_CHICK/25-122                .....lqledc-----------------.------.YGAPA..QRARYKRVRCRPDAWSPNCVEETGPWFQLPDGAAN....RILPPLA.N.PALMKTYQELGDAFPLSEEQ........SGSGWDAalemASGSGAE---------------..-----------------------------afpvvg..................
H2Q202_PANTR/3-155                 ...........QKLLKCSRLVLALALIL.VLESSV.QGYPT..QRARYQWVRCNPDSNSANCLEEKGPMFELLPGESN....KIPRLRT.D.LFPKTRIQDLNHIFPLSEDYsg....sgSGSGSGS....GSGSGSGSGSGFLTEMEQDYQL..VDESDAFHVNLRSLDRNLPSDSQDLGQHG........................
H0Z0A1_TAEGU/1-83                  ..........a-----------------.------.---PM..QRARYKRVRCRPEAWSANCVEEKGPWFYMPSGGAN....RILPPMA.D.PSLMKRYQDLGDIFPLSDED........SGSGSN-....----------------------..-----------------------------tvveaepasgs.............
I3LKI1_PIG/4-147                   kqlrsstlhlq-----------GLSLLLdEMEITV.QSSPV..RKARYQWVRCSPDSDSPNCIDEKGPVFDLLPGESN....RILPPRT.D.PFSMTRSKNLNDVFPLSEDF........SGSGSGA....GSGSGS------LNEIEQEYQP..VEENNAFYDNFRSLERNLPSDNQDLGLDG........................
S9X855_9CETA/2-146                 ...........QVILQGSRLFLALAFIL.ILDSSA.QGSPV..RRARYQWVRCNPDSNSANCIEEKGPVFNLLPGESN....RILPPRT.D.PFSMTRSKNLNDIFPLSEDF........----SGS....GSGSEAGSGSGFLSEIEQEYQP..VEENNDFYHNFRSLERNLPSDNEDLGQDG........................
A0A0D9R614_CHLSB/3-146             ...........QKLLKCSRLVLALALIL.VLESSV.QGYP-..--ARYQWVRCNPDSNSANCIEEKGPMFDLLPSESN....KIPRLRT.D.LFPKTRIQDLNRIFPLSEDY........--SGSGS....GSGSGSGSGSGFVTEMEQDYQP..VDESDAFHDNLRSLDRNLPSDSQDLGQHG........................
L9KSG6_TUPCH/3-151                 ...........QKLLKCTRMVLALFLIL.ALESSV.QGYPM..RRARYQWVRCSPDSNSANCIDEKGPLFDLLPEESN....RILPPRS.D.PFSMTKFRNLNDVYPLSEEY........SGSGSGS....GSGSGSGSGSGFLTEMEEEYQP..VDVNGPLDYFSRPLKTNLPSDFQDLGQD-v.......................
G3STW9_LOXAF/1-151                 .........it--VSHSQRLLVTRSFLL.GWDNST.KSHPM..RKARHQWVRCNPDSNSANCINERGPVFDLSPGESN....RILPPRN.D.PFSSEFCSS-TDYLPFVSNFt.....dfSGSGSGS....GSGSGLSSESIFPNEINQEYQP..VDGNNAFYHNFRPRGRDLPSDKQDSAQDG........................
F7HD78_CALJA/3-151                 ...........QKLFKCSRLVLALALIL.VLESSV.QGYPV..QRARYQWVRCSPDSNSANCIEEKGPMFDLLPSESN....KIPHLRT.D.PFPKTRFQDLNRIFPLSEDY........SGSGSGS....GSGSGSGSGNDFLTEMEQEYQL..ADERDAFHNNLMSLDRNLPSDGQDLGQPG........................
#=GC seq_cons                      .............l.pssRLlLALALlL.slpSSV.QGhPs..pRARYQWVRCsPDSNSANCI-EKGPhF-LlsGESN....+I.PsRT.D.sa.hp+.QsLN-lFPLSEDa........SGSGSGS....GSGSGSGSGSua.sEhEp-YQs..lDEsssFa.NhRshccsLPSDsQDLGpcG........................
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