GenomeNet

Database: Pfam
Entry: Sialidase_penC
LinkDB: Sialidase_penC
Original site: Sialidase_penC 
#=GF ID   Sialidase_penC
#=GF AC   PF12135.4
#=GF DE   Sialidase enzyme penultimate C terminal domain
#=GF AU   Mistry J, Gavin OL
#=GF SE   pdb_2vo8
#=GF GA   20.40 20.40;
#=GF TC   20.50 20.70;
#=GF NC   20.20 20.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   18716000
#=GF RT   Structural basis of Clostridium perfringens toxin complex
#=GF RT   formation.
#=GF RA   Adams JJ, Gregg K, Bayer EA, Boraston AB, Smith SP;
#=GF RL   Proc Natl Acad Sci U S A. 2008;105:12194-12199.
#=GF DR   INTERPRO; IPR021984;
#=GF CC   This domain is found in bacteria and eukaryotes, and is about 30
#=GF CC   amino acids in length. The protein from which this domain is
#=GF CC   found is a sialidase enzyme which is used by virulent bacteria
#=GF CC   as a toxin. It is the penultimate C terminal domain.
#=GF SQ   62
#=GS W7B0S0_PLAVN/1607-1631  AC W7B0S0.1
#=GS W7B0S0_PLAVN/1719-1743  AC W7B0S0.1
#=GS Q8XMY5_CLOPE/975-998    AC Q8XMY5.1
#=GS W7B0S0_PLAVN/1557-1581  AC W7B0S0.1
#=GS Q0TQN3_CLOP1/1272-1295  AC Q0TQN3.1
#=GS Q4XD88_PLACH/23-47      AC Q4XD88.1
#=GS Q25661_PLACH/1159-1183  AC Q25661.1
#=GS Q4YTY6_PLABA/1951-1974  AC Q4YTY6.1
#=GS H1CTR6_CLOPF/976-998    AC H1CTR6.1
#=GS V7PUF8_9APIC/472-496    AC V7PUF8.1
#=GS Q4YTY6_PLABA/2051-2075  AC Q4YTY6.1
#=GS B1V5X9_CLOPF/1279-1302  AC B1V5X9.1
#=GS W7B0S0_PLAVN/1644-1667  AC W7B0S0.1
#=GS Q25661_PLACH/1109-1133  AC Q25661.1
#=GS Q25661_PLACH/639-663    AC Q25661.1
#=GS Q4XD88_PLACH/73-97      AC Q4XD88.1
#=GS V7PUF8_9APIC/423-446    AC V7PUF8.1
#=GS Q25661_PLACH/614-638    AC Q25661.1
#=GS W7B0S0_PLAVN/1582-1605  AC W7B0S0.1
#=GS V7PUF8_9APIC/398-422    AC V7PUF8.1
#=GS Q25661_PLACH/1011-1035  AC Q25661.1
#=GS B1RSD2_CLOPF/1279-1302  AC B1RSD2.1
#=GS Q4YTY6_PLABA/2001-2025  AC Q4YTY6.1
#=GS H7CSY9_CLOPF/976-998    AC H7CSY9.1
#=GS Q25661_PLACH/1184-1208  AC Q25661.1
#=GS Q4XD88_PLACH/123-147    AC Q4XD88.1
#=GS Q0TTQ4_CLOP1/975-998    AC Q0TTQ4.1
#=GS Q0TTQ4_CLOP1/975-998    DR PDB; 2VO8 A; 969-992;
#=GS Q4XD88_PLACH/148-172    AC Q4XD88.1
#=GS B1RJL5_CLOPF/1279-1302  AC B1RJL5.1
#=GS Q25661_PLACH/824-848    AC Q25661.1
#=GS B1RD96_CLOPF/975-998    AC B1RD96.1
#=GS Q4XD88_PLACH/48-72      AC Q4XD88.1
#=GS Q25661_PLACH/874-898    AC Q25661.1
#=GS Q25661_PLACH/1233-1257  AC Q25661.1
#=GS Q25661_PLACH/762-786    AC Q25661.1
#=GS Q25661_PLACH/514-538    AC Q25661.1
#=GS B1BND4_CLOPF/976-998    AC B1BND4.1
#=GS Q25661_PLACH/1258-1282  AC Q25661.1
#=GS V7PUF8_9APIC/497-521    AC V7PUF8.1
#=GS Q25661_PLACH/849-873    AC Q25661.1
#=GS Q7RTC2_PLAYO/979-1002   AC Q7RTC2.1
#=GS Q4YTY6_PLABA/1926-1950  AC Q4YTY6.1
#=GS Q4YTY6_PLABA/2026-2050  AC Q4YTY6.1
#=GS B1V256_CLOPF/976-998    AC B1V256.1
#=GS W7B0S0_PLAVN/1694-1718  AC W7B0S0.1
#=GS B1RAZ0_CLOPF/1279-1302  AC B1RAZ0.1
#=GS Q8XKN0_CLOPE/1272-1295  AC Q8XKN0.1
#=GS Q7RTC2_PLAYO/1053-1077  AC Q7RTC2.1
#=GS B1BH07_CLOPF/975-998    AC B1BH07.1
#=GS Q25661_PLACH/539-563    AC Q25661.1
#=GS Q25661_PLACH/664-688    AC Q25661.1
#=GS Q4YTY6_PLABA/1976-2000  AC Q4YTY6.1
#=GS Q25661_PLACH/564-588    AC Q25661.1
#=GS Q25661_PLACH/737-761    AC Q25661.1
#=GS B1R3P4_CLOPF/975-998    AC B1R3P4.1
#=GS H1CRQ3_CLOPF/1279-1302  AC H1CRQ3.1
#=GS Q4XD88_PLACH/173-197    AC Q4XD88.1
#=GS H7CW97_CLOPF/1278-1301  AC H7CW97.1
#=GS Q7RTC2_PLAYO/1028-1052  AC Q7RTC2.1
#=GS Q7RTC2_PLAYO/954-978    AC Q7RTC2.1
#=GS Q25661_PLACH/961-985    AC Q25661.1
#=GS Q25661_PLACH/986-1010   AC Q25661.1
W7B0S0_PLAVN/1607-1631             .FPDSEVYTPKQEYFHNNEIYQLNGI.
W7B0S0_PLAVN/1719-1743             .FPGNEIYTTEQEGSLDEEIYSLNGI.
Q8XMY5_CLOPE/975-998               .-GDTEVYSAEYLFEYNVEAFILNEI.
W7B0S0_PLAVN/1557-1581             .FPNTQLYESNNEMYQNREIYSGNQI.
Q0TQN3_CLOP1/1272-1295             .-EDLSAYAAEFTLKYNQEVFDLVEV.
Q4XD88_PLACH/23-47                 .SPNTQLYESNNEMYQNRGIYNCDQI.
Q25661_PLACH/1159-1183             .FSDNETYITEQIGSLDEEIYPLTG-l
Q4YTY6_PLABA/1951-1974             .FSNGEIFTPKQGYFKNNEIYPLNE-.
H1CTR6_CLOPF/976-998               .--DTEAYSAEYLFEYNAEAFKLNEI.
V7PUF8_9APIC/472-496               .SSNSEVYSSEHEIEQNDEVYSLSGI.
Q4YTY6_PLABA/2051-2075             .FSDNEVYNPKHEVEKNDEIYALNEV.
B1V5X9_CLOPF/1279-1302             .-EDLSAYAAEFTLKYNPEVFDLVEV.
W7B0S0_PLAVN/1644-1667             l-SNNEVCTPKHEIEQYEEIYPLTG-.
Q25661_PLACH/1109-1133             l-SDNEIYITEQIGSLDEEIYPITGI.
Q25661_PLACH/639-663               .FSDNEIYITEQKGSLDKEIYPLTGV.
Q4XD88_PLACH/73-97                 .FPGSEVYSPKQEYSYNNDIYQLYGM.
V7PUF8_9APIC/423-446               .YQDREIYNYD-QIYQNREIYNYDQI.
Q25661_PLACH/614-638               l-SDCEVCTPKYEIEQNEEIYPLNGI.
W7B0S0_PLAVN/1582-1605             .FPDSEVYTPKQEYSHNNEIYQLNG-.
V7PUF8_9APIC/398-422               .FPNPQLYAFDNEIYQNREIYNYDQM.
Q25661_PLACH/1011-1035             .FSDNETYITEHIGSRNAQICPLNEV.
B1RSD2_CLOPF/1279-1302             .-EDLSAYAAEFTLKYNQEVFDLVEV.
Q4YTY6_PLABA/2001-2025             .FSDNEVYNPKREVEQNDEIYSLNGI.
H7CSY9_CLOPF/976-998               .--NTEAYSAEYLFEYNAEAFKLNEI.
Q25661_PLACH/1184-1208             .FSDNETYITEHIGSLNEEICPLNEV.
Q4XD88_PLACH/123-147               l-SDCEVCTPKYEIEQNEEIYPLNGI.
Q0TTQ4_CLOP1/975-998               .-GDTEVYSAEYLFEYNAEAFILNEI.
#=GR Q0TTQ4_CLOP1/975-998    SS    .-TT--EEEEEEEEE--TTTEEEEEE.
Q4XD88_PLACH/148-172               .FSDNEIYITEQKGSLDKEIYPLTGV.
B1RJL5_CLOPF/1279-1302             .-EDLSAYAAEFTLKYNPEVFDLVEV.
Q25661_PLACH/824-848               .SQDNEICTPKQEVSQNEEINTLNEI.
B1RD96_CLOPF/975-998               .-GDTEVYSAEYLFEYNAEAFKLNEI.
Q4XD88_PLACH/48-72                 .FPDSEVCIPKQEYFHNNEIYQLNGI.
Q25661_PLACH/874-898               .SSDNETYITEHIGSLNEEICPLNEV.
Q25661_PLACH/1233-1257             .SPDNEVYITEQIGSLDEEICPLNEV.
Q25661_PLACH/762-786               .FSDNETYITEHIGSLNEEICPLNEV.
Q25661_PLACH/514-538               .SPNTQLYESNNEMYQNRGIYNCDQI.
B1BND4_CLOPF/976-998               .--DTEAYSAEYLFEYNAEAFKLNEI.
Q25661_PLACH/1258-1282             .SPDIEVYITEQIGSFDEEIYSLTGI.
V7PUF8_9APIC/497-521               .FSDNEIRSSEHEIEQSDEVYSLNGI.
Q25661_PLACH/849-873               l-SDNEIHITEQIGSPNEEIYPLTGV.
Q7RTC2_PLAYO/979-1002              .YQDREIYNYD-QIYQNREIYNYDQI.
Q4YTY6_PLABA/1926-1950             .FPNPQLYASNNEIDQNREIYNYNQI.
Q4YTY6_PLABA/2026-2050             .FSDNEVYNPKREVEQNDETYSLTGI.
B1V256_CLOPF/976-998               .--DTEAYSAEYLFEYNAEAFKLNEI.
W7B0S0_PLAVN/1694-1718             .FPDNEVYTTEKIGSPDEKIYPLNEI.
B1RAZ0_CLOPF/1279-1302             .-EDLSAYAAEFTLKYNQEVFDLVEV.
Q8XKN0_CLOPE/1272-1295             .-EDLSAYAAEFTLKYNPEVFDLVEV.
Q7RTC2_PLAYO/1053-1077             .FSDNEIRSSEHEIEQSDEVYSLNGI.
B1BH07_CLOPF/975-998               .-GDTEVYSAEYLFEYNAEAFKLNEI.
Q25661_PLACH/539-563               .FPDSEVCIPKQEYFHNNEIYQLNGI.
Q25661_PLACH/664-688               .FSDNETYITEHIGSLNEEICPLNEV.
Q4YTY6_PLABA/1976-2000             .SSNSEVYSSEHEIEQNDETYSLTGI.
Q25661_PLACH/564-588               .FPGSEVYSPKQEYSYNNDIYQLYGM.
Q25661_PLACH/737-761               .FSDNETYITEQKGSLDKEIYPLTGV.
B1R3P4_CLOPF/975-998               .-GDTEAYSAEYLFEYNAEAFKLNEI.
H1CRQ3_CLOPF/1279-1302             .-EDLSAYAAEFTLKYNQEVFDLVEV.
Q4XD88_PLACH/173-197               .FSDNETYITEHIGSLNEEICPLNEV.
H7CW97_CLOPF/1278-1301             .-EDLSAYAAEFTLKYNQEVFDLVEV.
Q7RTC2_PLAYO/1028-1052             .SSNSEVYSSEHEIEQNDEVYSLSGI.
Q7RTC2_PLAYO/954-978               .FPNPQLYAFDNEIYQNREIYNYDQM.
Q25661_PLACH/961-985               l-SDNEIHITEQIGSPNEEIYPLTGV.
Q25661_PLACH/986-1010              .FSDNETYITEQIGSLDEEIYPLTG-l
#=GC SS_cons                       .-TT--EEEEEEEEE--TTTEEEEEE.
#=GC seq_cons                      ..sDsElYssEpphphNpEIasLstl.
//
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