GenomeNet

Database: Pfam
Entry: Sialidase_penC
LinkDB: Sialidase_penC
Original site: Sialidase_penC 
#=GF ID   Sialidase_penC
#=GF AC   PF12135.3
#=GF DE   Sialidase enzyme penultimate C terminal domain
#=GF AU   Mistry J, Gavin OL
#=GF SE   pdb_2vo8
#=GF GA   20.40 20.40;
#=GF TC   21.20 21.80;
#=GF NC   20.00 18.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   18716000
#=GF RT   Structural basis of Clostridium perfringens toxin complex
#=GF RT   formation.
#=GF RA   Adams JJ, Gregg K, Bayer EA, Boraston AB, Smith SP;
#=GF RL   Proc Natl Acad Sci U S A. 2008;105:12194-12199.
#=GF DR   INTERPRO; IPR021984;
#=GF CC   This domain is found in bacteria and eukaryotes, and is about 30
#=GF CC   amino acids in length. The protein from which this domain is
#=GF CC   found is a sialidase enzyme which is used by virulent bacteria
#=GF CC   as a toxin. It is the penultimate C terminal domain.
#=GF SQ   64
#=GS Q25661_PLACH/713-736    AC Q25661.1
#=GS Q25661_PLACH/1084-1108  AC Q25661.1
#=GS Q25661_PLACH/936-960    AC Q25661.1
#=GS Q4YTY6_PLABA/1951-1974  AC Q4YTY6.1
#=GS Q25661_PLACH/1109-1133  AC Q25661.1
#=GS B1V256_CLOPF/974-998    AC B1V256.1
#=GS Q8XMY5_CLOPE/974-998    AC Q8XMY5.1
#=GS Q25661_PLACH/639-663    AC Q25661.1
#=GS Q4XD88_PLACH/73-97      AC Q4XD88.1
#=GS Q0TTQ4_CLOP1/974-998    AC Q0TTQ4.1
#=GS Q0TTQ4_CLOP1/974-998    DR PDB; 2VO8 A; 968-992;
#=GS H7CW97_CLOPF/1277-1301  AC H7CW97.1
#=GS Q25661_PLACH/1011-1035  AC Q25661.1
#=GS Q25661_PLACH/1184-1208  AC Q25661.1
#=GS Q4XD88_PLACH/123-147    AC Q4XD88.1
#=GS Q25661_PLACH/1209-1232  AC Q25661.1
#=GS Q25661_PLACH/824-848    AC Q25661.1
#=GS Q25661_PLACH/986-1009   AC Q25661.1
#=GS Q25661_PLACH/874-898    AC Q25661.1
#=GS Q25661_PLACH/689-712    AC Q25661.1
#=GS B1RSD2_CLOPF/1278-1302  AC B1RSD2.1
#=GS Q25661_PLACH/762-786    AC Q25661.1
#=GS B1BH07_CLOPF/974-998    AC B1BH07.1
#=GS Q25661_PLACH/514-538    AC Q25661.1
#=GS H7CSY9_CLOPF/974-998    AC H7CSY9.1
#=GS Q8XKN0_CLOPE/1271-1295  AC Q8XKN0.1
#=GS Q25661_PLACH/1060-1083  AC Q25661.1
#=GS Q25661_PLACH/1159-1182  AC Q25661.1
#=GS Q25661_PLACH/664-688    AC Q25661.1
#=GS Q25661_PLACH/737-761    AC Q25661.1
#=GS B1R3P4_CLOPF/974-998    AC B1R3P4.1
#=GS Q7RTC2_PLAYO/1028-1052  AC Q7RTC2.1
#=GS Q25661_PLACH/899-922    AC Q25661.1
#=GS Q25661_PLACH/961-985    AC Q25661.1
#=GS H1CRQ3_CLOPF/1278-1302  AC H1CRQ3.1
#=GS Q4XD88_PLACH/23-47      AC Q4XD88.1
#=GS Q4YTY6_PLABA/2051-2075  AC Q4YTY6.1
#=GS Q25661_PLACH/1036-1059  AC Q25661.1
#=GS B1BND4_CLOPF/974-998    AC B1BND4.1
#=GS Q25661_PLACH/614-638    AC Q25661.1
#=GS Q4YTY6_PLABA/2001-2025  AC Q4YTY6.1
#=GS B1BFF7_CLOPF/1278-1302  AC B1BFF7.1
#=GS Q4XD88_PLACH/148-172    AC Q4XD88.1
#=GS B1V5X9_CLOPF/1278-1302  AC B1V5X9.1
#=GS Q0TQN3_CLOP1/1271-1295  AC Q0TQN3.1
#=GS Q4XD88_PLACH/48-72      AC Q4XD88.1
#=GS B1RD96_CLOPF/974-998    AC B1RD96.1
#=GS Q25661_PLACH/1233-1257  AC Q25661.1
#=GS Q25661_PLACH/787-810    AC Q25661.1
#=GS B1BX42_CLOPF/1278-1302  AC B1BX42.1
#=GS B1RJL5_CLOPF/1278-1302  AC B1RJL5.1
#=GS B1RAZ0_CLOPF/1278-1302  AC B1RAZ0.1
#=GS Q25661_PLACH/1258-1282  AC Q25661.1
#=GS Q7RTC2_PLAYO/979-1002   AC Q7RTC2.1
#=GS Q25661_PLACH/849-873    AC Q25661.1
#=GS Q4YTY6_PLABA/1926-1950  AC Q4YTY6.1
#=GS Q4YTY6_PLABA/2026-2050  AC Q4YTY6.1
#=GS Q7RTC2_PLAYO/1053-1077  AC Q7RTC2.1
#=GS Q25661_PLACH/539-563    AC Q25661.1
#=GS Q4YTY6_PLABA/1976-2000  AC Q4YTY6.1
#=GS Q25661_PLACH/564-588    AC Q25661.1
#=GS Q4XD88_PLACH/173-197    AC Q4XD88.1
#=GS Q0STI7_CLOPS/7-30       AC Q0STI7.1
#=GS Q7RTC2_PLAYO/954-978    AC Q7RTC2.1
#=GS H1CTR6_CLOPF/974-998    AC H1CTR6.1
Q25661_PLACH/713-736               ...LPNNEV-ITEQDGSLDEEIYPLTGV.
Q25661_PLACH/1084-1108             ...FSDNKISTPRQIGSRNAEICPLNEV.
Q25661_PLACH/936-960               ...SQEEEISTPKQKGSQEEEINILNEI.
Q4YTY6_PLABA/1951-1974             ...FSNGEIFTPKQGYFKNNEIYPLNE-.
Q25661_PLACH/1109-1133             ...LSDNEIYITEQIGSLDEEIYPITGI.
B1V256_CLOPF/974-998               .nr--DTEAYSAEYLFEYNAEAFKLNEI.
Q8XMY5_CLOPE/974-998               ..n-GDTEVYSAEYLFEYNVEAFILNEI.
Q25661_PLACH/639-663               ...FSDNEIYITEQKGSLDKEIYPLTGV.
Q4XD88_PLACH/73-97                 ...FPGSEVYSPKQEYSYNNDIYQLYGM.
Q0TTQ4_CLOP1/974-998               ..n-GDTEVYSAEYLFEYNAEAFILNEI.
#=GR Q0TTQ4_CLOP1/974-998    SS    ..--TT--EEEEEEEEE--TTTEEEEEE.
H7CW97_CLOPF/1277-1301             ..k-EDLSAYAAEFTLKYNQEVFDLVEV.
Q25661_PLACH/1011-1035             ...FSDNETYITEHIGSRNAQICPLNEV.
Q25661_PLACH/1184-1208             ...FSDNETYITEHIGSLNEEICPLNEV.
Q4XD88_PLACH/123-147               ...LSDCEVCTPKYEIEQNEEIYPLNGI.
Q25661_PLACH/1209-1232             ...VPDNEV-ITEQIGSLDEAICPLNEV.
Q25661_PLACH/824-848               ...SQDNEICTPKQEVSQNEEINTLNEI.
Q25661_PLACH/986-1009              ...FSDNETYITEQIGSLDEEIYPLTG-.
Q25661_PLACH/874-898               ...SSDNETYITEHIGSLNEEICPLNEV.
Q25661_PLACH/689-712               ..l-LDNEI-ITEQIGSHDEEIYPLNEI.
B1RSD2_CLOPF/1278-1302             ..k-EDLSAYAAEFTLKYNQEVFDLVEV.
Q25661_PLACH/762-786               ...FSDNETYITEHIGSLNEEICPLNEV.
B1BH07_CLOPF/974-998               ..n-GDTEVYSAEYLFEYNAEAFKLNEI.
Q25661_PLACH/514-538               ...SPNTQLYESNNEMYQNRGIYNCDQI.
H7CSY9_CLOPF/974-998               .nr--NTEAYSAEYLFEYNAEAFKLNEI.
Q8XKN0_CLOPE/1271-1295             ..k-EDLSAYAAEFTLKYNPEVFDLVEV.
Q25661_PLACH/1060-1083             ...LSENEV-ITEQIGSNDGEMYSLNEV.
Q25661_PLACH/1159-1182             ...FSDNETYITEQIGSLDEEIYPLTG-.
Q25661_PLACH/664-688               ...FSDNETYITEHIGSLNEEICPLNEV.
Q25661_PLACH/737-761               ...FSDNETYITEQKGSLDKEIYPLTGV.
B1R3P4_CLOPF/974-998               ..n-GDTEAYSAEYLFEYNAEAFKLNEI.
Q7RTC2_PLAYO/1028-1052             ...SSNSEVYSSEHEIEQNDEVYSLSGI.
Q25661_PLACH/899-922               ..l-LDNEI-ITEQIGSNNGEMYSLNEV.
Q25661_PLACH/961-985               ...LSDNEIHITEQIGSPNEEIYPLTGV.
H1CRQ3_CLOPF/1278-1302             ..k-EDLSAYAAEFTLKYNQEVFDLVEV.
Q4XD88_PLACH/23-47                 ...SPNTQLYESNNEMYQNRGIYNCDQI.
Q4YTY6_PLABA/2051-2075             ...FSDNEVYNPKHEVEKNDEIYALNEV.
Q25661_PLACH/1036-1059             ...FQDNEV-TTEQIGSLDEAICPLNEV.
B1BND4_CLOPF/974-998               .nr--DTEAYSAEYLFEYNAEAFKLNEI.
Q25661_PLACH/614-638               ...LSDCEVCTPKYEIEQNEEIYPLNGI.
Q4YTY6_PLABA/2001-2025             ...FSDNEVYNPKREVEQNDEIYSLNGI.
B1BFF7_CLOPF/1278-1302             keg---LSAYAAEFTLKYNQEVFDLVEV.
Q4XD88_PLACH/148-172               ...FSDNEIYITEQKGSLDKEIYPLTGV.
B1V5X9_CLOPF/1278-1302             ..k-EDLSAYAAEFTLKYNPEVFDLVEV.
Q0TQN3_CLOP1/1271-1295             ..k-EDLSAYAAEFTLKYNQEVFDLVEV.
Q4XD88_PLACH/48-72                 ...FPDSEVCIPKQEYFHNNEIYQLNGI.
B1RD96_CLOPF/974-998               ..n-GDTEVYSAEYLFEYNAEAFKLNEI.
Q25661_PLACH/1233-1257             ...SPDNEVYITEQIGSLDEEICPLNEV.
Q25661_PLACH/787-810               ..l-LDNEI-ITEQIGSLDEAICPLNEI.
B1BX42_CLOPF/1278-1302             keg---LSAYAAEFTLKYNQEVFDLVEV.
B1RJL5_CLOPF/1278-1302             ..k-EDLSAYAAEFTLKYNPEVFDLVEV.
B1RAZ0_CLOPF/1278-1302             ..k-EDLSAYAAEFTLKYNQEVFDLVEV.
Q25661_PLACH/1258-1282             ...SPDIEVYITEQIGSFDEEIYSLTGI.
Q7RTC2_PLAYO/979-1002              ...YQDREIYNYDQIY-QNREIYNYDQI.
Q25661_PLACH/849-873               ...LSDNEIHITEQIGSPNEEIYPLTGV.
Q4YTY6_PLABA/1926-1950             ...FPNPQLYASNNEIDQNREIYNYNQI.
Q4YTY6_PLABA/2026-2050             ...FSDNEVYNPKREVEQNDETYSLTGI.
Q7RTC2_PLAYO/1053-1077             ...FSDNEIRSSEHEIEQSDEVYSLNGI.
Q25661_PLACH/539-563               ...FPDSEVCIPKQEYFHNNEIYQLNGI.
Q4YTY6_PLABA/1976-2000             ...SSNSEVYSSEHEIEQNDETYSLTGI.
Q25661_PLACH/564-588               ...FPGSEVYSPKQEYSYNNDIYQLYGM.
Q4XD88_PLACH/173-197               ...FSDNETYITEHIGSLNEEICPLNEV.
Q0STI7_CLOPS/7-30                  ..v--NVEAFAYDFTLNYDENAFEYVE-a
Q7RTC2_PLAYO/954-978               ...FPNPQLYAFDNEIYQNREIYNYDQM.
H1CTR6_CLOPF/974-998               .nr--DTEAYSAEYLFEYNAEAFKLNEI.
#=GC SS_cons                       ..--TT--EEEEEEEEE--TTTEEEEEE.
#=GC seq_cons                      ....sDsElYtsEphhphNpElasLspl.
//
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