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Database: Pfam
Entry: Sigma_1s
LinkDB: Sigma_1s
Original site: Sigma_1s 
#=GF ID   Sigma_1s
#=GF AC   PF02454.11
#=GF DE   Sigma 1s protein
#=GF AU   Mian N, Bateman A
#=GF SE   Pfam-B_2133 (release 5.4)
#=GF GA   20.10 20.10;
#=GF TC   21.00 29.10;
#=GF NC   19.80 19.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   2398530
#=GF RT   Sequence diversity in S1 genes and S1 translation products of 11
#=GF RT   serotype 3 reovirus strains. 
#=GF RA   Dermody TS, Nibert ML, Bassel-Duby R, Fields BN; 
#=GF RL   J Virol 1990;64:4842-4850.
#=GF DR   INTERPRO; IPR003478;
#=GF CC   The reoviral gene S1 encodes for haemagglutinin (sigma 1
#=GF CC   protein), an outer capsid protein and a major factor in
#=GF CC   determining virus-host cell interactions. Sigma 1s is one of two
#=GF CC   translation products of the S1 gene.
#=GF SQ   20
#=GS Q76SC0_9REOV/5-120  AC Q76SC0.1
#=GS Q85687_9REOV/5-120  AC Q85687.1
#=GS Q86334_9REOV/5-120  AC Q86334.1
#=GS Q76T49_9REOV/3-125  AC Q76T49.1
#=GS Q89910_9REOV/5-120  AC Q89910.1
#=GS Q86330_9REOV/5-120  AC Q86330.1
#=GS Q85685_9REOV/5-120  AC Q85685.1
#=GS Q76SC1_9REOV/5-120  AC Q76SC1.1
#=GS Q86336_9REOV/5-120  AC Q86336.1
#=GS D1MLL3_9REOV/2-113  AC D1MLL3.1
#=GS Q86332_9REOV/5-120  AC Q86332.1
#=GS SIG1S_REOVD/5-120   AC P03529.1
#=GS Q85696_9REOV/5-120  AC Q85696.1
#=GS SIG1S_REOVJ/3-125   AC P32868.1
#=GS Q85689_9REOV/5-120  AC Q85689.1
#=GS SIG1S_REOVL/1-115   AC P07938.1
#=GS Q86338_9REOV/5-120  AC Q86338.1
#=GS Q85698_9REOV/5-120  AC Q85698.1
#=GS Q8V5E3_9REOV/6-79   AC Q8V5E3.1
#=GS Q85691_9REOV/5-120  AC Q85691.1
Q76SC0_9REOV/5-120             ...CQKGLNQGSRRSRRRLKYTLILSSGSPRDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALPEPSKQLSMDLIRVLPSWVLEWDNLRQDLQSYALTTTISL...REWILRN....VTLDH......................
Q85687_9REOV/5-120             ...CQKGLNQGSRRSRRRLKYTLILSSGSPRDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALPEPSKQLSMDLIRVLPSWVLEWDNLRQDLQSYALITTISL...REWILRN....VTLDH......................
Q86334_9REOV/5-120             ...CQKGLNQGSRRSRRRLKYTLILSSGSPRDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALSEPSKQLSMDLIRVLPSWVLEWDNLRQDLQSYALTTTISL...REWILQN....VTLDH......................
Q76T49_9REOV/3-125             ...NQPTRNTRSRKLRNKLKTSLLMSTGSVTSLIQSKDNWVDYLYACQPLNRELVRTAIELIDSSEMSPAYRLALAESIRVYPSWVTESMLQNSELASWIQSRIISLsehQDWKLKYqpllMTLDH......................
Q89910_9REOV/5-120             ...CQKGLNQGSRRSRRRLKYTLILSSGSPRDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALPEPSKQLSMDLIRVLPSWVLEWDNLRQDLQSYALTTTISL...REWILRN....VTLDH......................
Q86330_9REOV/5-120             ...CQKGLNQGSRRSRRRLKYTLILSSGSPRDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALSEPSKQLSMDLIRVLPSWVLEWDNLRQDLQSYALITAISL...REWILQN....VTLDH......................
Q85685_9REOV/5-120             ...CQKDLSRGSRRLRKRPKYTLIQSLGSLRDSMMQTNESALLSKVGTIWLHQLVMHNLQSPDWKTLSEPSRQLSMDLIRVLPSWVVEWDNLRQDLQDYAMTTAVSL...REWIVQN....AILDH......................
Q76SC1_9REOV/5-120             ...CQKGLNQGSRRSRRRLKYTLILSSGSPRDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALPEPSKQLSMDLIRVLPSWVLEWDNLRQDLQSYALTTTISL...REWILRN....VTLDH......................
Q86336_9REOV/5-120             ...CQKGLNQGSRRSRRRLKYTLILSSGSPRDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALSEPAKQLSMDLIRVLPSWVLEWDNLRQDLQSYALITTISL...REWILQN....VTLDH......................
D1MLL3_9REOV/2-113             .ec-----RKKPRKSRNRSNNSVMMSLGSATSFRLNADSLMASLRASQPLNQEWVIWATESLLMSGLSSQSLQSWAQSLIVYPPWVSESMLQNKELRDWIQSRVISL...AEHPYWR....QM---sq....................
Q86332_9REOV/5-120             ...CQKGLNQGSRRSRRRLKYTLILSSGSPRDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALSEPSKQLSMDLIRVLPSWVLEWDNLRQDLQSYALSTAISL...REWILQN....VTLDH......................
SIG1S_REOVD/5-120              ...CQKGLNQGSRRSRRRLKYTLILSSGSPRDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALSEPSKQLSMDLIRVLPSWVLEWDNLRQDLQSYALITTISL...REWILQN....VTLDH......................
Q85696_9REOV/5-120             ...CQKGLNRGSRRLRKRPKYTLIQSSGSLRDSMMQINESSLLSKVGTIWLHQLVTRNLQSPDWKALSEPSKQLSMDLIRVLPSWVVEWDSLRQDLQDYAMTTAVSL...REWVHRN....ATLDH......................
SIG1S_REOVJ/3-125              ...NQPTRNTRSRKLRNKLKTSLLMSTGSVTSLIQSKDNWVDYLYACQPLNRELVRTAIELIDSSEMSPAYRLALAESIRVYPSWVTESMLQNSELASWIQSRIISLsehQDWKLKYqpllMTLDH......................
Q85689_9REOV/5-120             ...CQKGLNQGSRRSRRRLKYTLILSSGSPRDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALPEPSKQLSMDLIRVLPNWVLEWDNLRQDLQSYALTTTISL...REWILRN....VTLDH......................
SIG1S_REOVL/1-115              ...MAPS-QKKSRKSRNKSRSTLMISGLPILNSTDLEDRLLTSAIASQPLSQDWVRWIIDLWVSRVRSRNYLTQVARTLRAYPHWVTESMLSNHELTVWIRSRLISL...DEHPLWR....QMLEA......................
Q86338_9REOV/5-120             ...CQKGLNQGSRRSRRRLKYTLILSSGSPTDSMMQTNESSLLSKVGMTWLHQSVMLNLQSPDWKALSEPSKQLSMDLIRVLPSWVLEWDNLRQDLQSYALITTISL...REWILQN....VTLDH......................
Q85698_9REOV/5-120             ...CQKDSSRGSRRLRKRPRYTLIQSLGSLRDSRMQINQSALLRRVGTIWLHQLVMRNLQSPDWKALSEPSKQLSMDLIRVLPSWVVEWDSLRQDLQDYAMTTAVSL...REWVMRN....ETLDH......................
Q8V5E3_9REOV/6-79              lrd----LRRESKRLRKHRKYTQIASFGSIRTSMMPVSASSLLSKVGTPLVTSVSD---------------------------------------------------...-------....-----aqlaisrlessvsslqgsvngl
Q85691_9REOV/5-120             ...CQRALNQGSKRSRKRPKYTLIQSLGLLKDSMTQTNESSLLSKVGTIWLHQSVMRNLQSPDWKALSEPSKQLSMDLIQVLPRLVAEWENLRQDLQDYALTMTVSL...REWILRN....VTLDH......................
#=GC seq_cons                  ...CQKGLNQGSRRSR+RLKYTLIlSSGSsRDSMMQTNESSLLSKVGhsWLHQSVMhNLQSPDWKALSEPSKQLSMDLIRVLPSWVlEWDNLRQDLQSYALoTsISL...REWILpN....VTLDH......................
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