GenomeNet

Database: Pfam
Entry: Sporozoite_P67
LinkDB: Sporozoite_P67
Original site: Sporozoite_P67 
#=GF ID   Sporozoite_P67
#=GF AC   PF05642.9
#=GF DE   Sporozoite P67 surface antigen
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_8657 (release 8.0)
#=GF GA   28.00 28.00;
#=GF TC   28.20 28.30;
#=GF NC   27.90 27.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10024569
#=GF RT   Linear peptide specificity of bovine antibody responses to p67
#=GF RT   of Theileria parva and sequence diversity of
#=GF RT   sporozoite-neutralizing epitopes: implications for a vaccine. 
#=GF RA   Nene V, Gobright E, Bishop R, Morzaria S, Musoke A; 
#=GF RL   Infect Immun 1999;67:1261-1266.
#=GF DR   INTERPRO; IPR008845;
#=GF CC   This family consists of several Theileria P67 surface antigens.
#=GF CC   A stage specific surface antigen of Theileria parva, p67, is the
#=GF CC   basis for the development of an anti-sporozoite vaccine for the
#=GF CC   control of East Coast fever (ECF) in cattle. The antigen has
#=GF CC   been shown to contain five distinct linear peptide sequences
#=GF CC   recognised by sporozoite-neutralising murine monoclonal
#=GF CC   antibodies [1].
#=GF SQ   18
#=GS Q4UCF0_THEAN/1-260      AC Q4UCF0.1
#=GS B4Q5H9_DROSI/2-374      AC B4Q5H9.1
#=GS Q27040_THEPA/297-709    AC Q27040.1
#=GS Q27040_THEPA/142-298    AC Q27040.1
#=GS B4JLF1_DROGR/275-521    AC B4JLF1.1
#=GS B4KEJ9_DROMO/12-376     AC B4KEJ9.2
#=GS Q4UCF0_THEAN/318-454    AC Q4UCF0.1
#=GS Q4UCF0_THEAN/449-917    AC Q4UCF0.1
#=GS U6GPL3_9EIME/3-285      AC U6GPL3.1
#=GS Q27040_THEPA/1-145      AC Q27040.1
#=GS U6K223_9EIME/457-736    AC U6K223.1
#=GS U6GL42_9EIME/177-474    AC U6GL42.1
#=GS Q9VJT7_DROME/7-369      AC Q9VJT7.2
#=GS U6KMX8_EIMTE/132-512    AC U6KMX8.1
#=GS U6MB75_EIMMA/1209-1459  AC U6MB75.1
#=GS U6LTR1_9EIME/130-444    AC U6LTR1.1
#=GS U6LPV0_9EIME/671-969    AC U6LPV0.1
#=GS B4HXF2_DROSE/5-361      AC B4HXF2.1
Q4UCF0_THEAN/1-260                 .....................................MNIIHFLLTIPVIFVSGADKMPAGESSRTSKPSPLVTLESAVTQPSKDP.FKTISALSKATKVWKSAVSVSGDSKTVPTPVSEPMITRS.FQEP..................VSQELEFQSDTEINESGS.GSDEDEDDDDD.........EEEEEDDK..STSSKNGKG.SPKA.QPGVSSSSTSSASPTSPT...........TTLSQTGLG.....PSGSH........AQQDPGVGV.PGVgvpg..........................vgvpgVGVPGVGVPGVGVPGVGgvpGVGV.APGV.G..V..PGV.GVA.PGVGVG...................................AdSSGL................................................PGSGG........................................................................................L----.-------...-------------.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------gagakagkgqg...............................................................
B4Q5H9_DROSI/2-374                 ................................etipa-------------------------------------------------.---------------------------------------.----..................------------------.-----------.........--------..---------.----.------------------...........---------.....-----........---------.TPV...................................VSTDTASVVGVGVGGVG...GGGA.AAGA.GggA..GGA.GGL.LGDVVS...................................G.LGGGlvneseayaglmkdadklk.........lmllawnyqnstavrngtegP---Dlsvvgglwaqyqnalaqnaaaaaa........................................asgkmdsslspvprqdahspmetqDETNS.SGQKEED...EVSEDDSDDKLDEklatthdperiihlaihlvtsakrvsitsipsfqmfvrlfvdenldriipiskqpkekiqaiidscarqfpefsdrsrkrirtylkscrrnkktrdgwenttrptpahltsvqaeqilaiacenesmnakrmriglepithavpaPGSAVAAAA-.........................AAAAAAAVVAAT.SSSAGGTSTTAAGnATATCGMG-------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------gvgdatgltsaaaaalp.........................................................
Q27040_THEPA/297-709               ...................................pp-------------------------------------------------.---------------------------------------.----..................------------------.-----------.........--------..---------.----.------------------...........---------.....-----........---------.---...................................-----------------...----.----.-..-..---.---.------...................................-.----................................................-----........................................................................................-----.-------...-------------.................................................................................................................................................----------.........................------------.-------------.----------------------SAPVPSPGAPGIIVRES..........GNRAMDIVQFLGRFKPEPRAYEGERTNVAELKKFLFEELESLVNTLIELKLAIASDFVEITDGLRKNTKDHEARLKLLRGVEFTKRKSVANVVKGFSSLYCVLLMNMNVIKEKTKESEVADGIWKLSTIPDKVANELLLAMEKIVVPPKTPELEEAFEAIEFGFKIAYYATKDILSSIENTVHNLMHAKNYEENFIAQVRNSLRMVPHQMNLTESSFVIKISDMMRRRGTASQDEPAGAGSgvtpgrgssgtgraAGTGGGSLRGLDLSEEEVKKILDEIVKDPSDGELGLGDLSDPSGRSSERQPS-LGPSLVITDGQAGPTIVSPTGPTI------------AAGGEQPPSAPNGTATGPAGTQPEGGEKKEGLIQKLKKKLLGSGFEVASLMIPMATIIISIVH..........................................................................
Q27040_THEPA/142-298               ..................................stl-------------------------------------------------.-------------------STDVSPTIPTPVSEEIITPT.LQAQ..................TKEEVPPA-DLSDQVPSN.GS---------.........DSEEEDNK..STSSKDEKE.LKKTlQPG-KTSTGETTSGQDLN...........SKQQQTGVSd...lASGSH........---------.---...................................--SSGLKVPGVGVPG--...----.----.-..-..---.AVS.PQGGQS...................................-.----................................................-----........................................................................................LASNT.SREGQAQ...HQQVRDGDGRVIE.................................................................................................................................................PKIGLPG---.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------pp........................................................................
B4JLF1_DROGR/275-521               ..........................irhsdnlrshn-------------------------------------------------.-------------------------------SSSSVTSStYKSH..................SQQQMQQQQQHQQQQQHH.HSSQRRSHDER.........-VRRRRDS..RTRSRSGSR.SRTR.TPI-DTPPLRRRQGQQST...........RKYRRRESC.....DSSSRs.....rsP-----VER.PPVhvrkpsd.....................vdphtrvYSTAGLLQGKLTLPSTA...AVSA.AAAL.N..A..AAI.SAAgSGVGGG...................................G.VGGG................................................-----........................................................................................-----.-------...-------------.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------ggllptpnyapkipslmslelnappsvlidgppaavqlpkyynpgivnanryaeqqqkrkliwgskknedsank
B4KEJ9_DROMO/12-376                ........................hketipaapatst-------------------------------------------------.---------------------------------------.----..................------------------.-----------.........--------..---------.----.------------------...........---------.....-----........-------DT.SSL...................................VGVGGGGGGGVGGGGVG..sGAGG.AGSG.L..V..DIA.NSL.SGGGSG...................................G.GGGG................................................GG--ItneseayaglmkdadklklmllawnyqnstavrngtegpdlsvvgglwaqyqnalaqnaaavaaanskmdsslspvprqdapspmeaqDETNS.SGQKEED...EVSEDDSDDKLDEklatphdperlkafnmfvrlfvdenldriipiskqpkekiqaiidscarqfpefsdrsrkrir...................tylkscrrnkktrdgwenttrptpahltsvqaeqilaiacenesmnakrmriglepithavpaPGSVVAAAAA.........................AAAVAGTSTTSA.SNAATVTCTAADA.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------aglssvaaaalpfvsavgfarstpn.................................................
Q4UCF0_THEAN/318-454               ................................ggkpg-------------------------------------------------.---------------------------------------.--QP..................VSQELELKSDTEINES--.GSSSEGEDDDD.........EEEEEENK..STSSKGAGGkAGKG.QGSVSPGGGSSASQTSPT...........TT-PQSGLA.....SSGSHaq....qsPQQDPAPSK.PSG...................................GGVPGVGVPGVGVPGVGv.pGVGV.APGV.G..V..V--.---.------...................................-.----................................................-----........................................................................................-----.-------...-------------.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------pgvg......................................................................
Q4UCF0_THEAN/449-917               ....................................v-------------------------------------------------.---------------------------------------.----..................------------------.-----------.........--------..---------.----.------------------...........---------.....-----........---------.---...................................-----------------...----.----.-..-..---.---.------...................................-.----................................................-----........................................................................................-----.-------...-------------.................................................................................................................................................----VPGVG-.........................GATTSSSSTTST.STSTTTTTTTSSGkPSNQGSHGTSPRNAVTRQTDSISGPIPSPGDPRAITGQMgllyssksfvGEGERFAVQFLGDFKPKPRRYEGQGTDAVKLKQFIFEEVKSLVQTLINLKLAIANDFVEISEKLKKKNQNYVPKLKLLKGEQFDTKQKVANVLKGFNSLYFVFFMNLNLAKEVNKPEELAEFLWKLNTIPDKVGREFELAIEKTKGSEKKKELEEAFNSIGLGFKIAQYATNDILSSITNSVYSLIKLKNFGDDFVTEVRKSLQMVPHQKNLNGSAFIVKISEIINKKGTEDQDQTSGSGS..............KGTEGGSLRGQDLTEEEVLKVLDELVKDVSEEHVGIGDLSDPSSRTPNAKPAELGPSLVIQNVPSDPSKVTPTQPSNLPQVPTTGPGNGTDGTTTGP-----GGNGEGGKDLKEGEKKEGLFQKIKNKLLGSGFEVASIIIPMTTIIFSIVH..........................................................................
U6GPL3_9EIME/3-285                 ivktataaaaaaaataaaaagivaaavpqrrkkqqqq-------------------------------------------------.---------------------------------------.QQQD..................QQQQQQQQDQQQQQQQQDqQQQQHQQDQQQ.........QQQQQDQQ..QQQQQQQQE.QQQQ.QQQQDLLQQQQQQQQQQQ...........QQQQQQQQG.....DSGVHt......lQQRHPATAA.KAA...................................ATATAVAAPALGAAAAA...AAVA.AADA.A..V..LAV.AVV.VTVATP...................................A.AGAVaaavaa....................................aaaaisP---Gpllcvllsklefspphnllpeaaaaaaaaa............................tvaaaaaaaaaaklprnitnynctgsnsnsNSSNSnSSELQQQ...QQQ----------.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------pqqkhhhlqqq...............................................................
Q27040_THEPA/1-145                 .....................................MQITQFLLIIPVLFVSAGDKMPTEEQPFPSRLGPLVTLESAITQPTAVYtMRTVGNVAKAAKAWKSAVSSSDVSTTIPTPVSEENITST.LQTQteevpaasgsdsytvtnlVQTQSQVQDNVKQQQDTK.GNRSDSEEENE.........DS------..---------.----.------------------...........---------.....-----........---------.---...................................-----------------...----.----.-..-..---.---.------...................................-.----................................................-----........................................................................................-----.-------...-------------.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------tls.......................................................................
U6K223_9EIME/457-736               .............................assnnppn-------------------------------------------------.---------------------------------------.----..................------------------.-----------.........--------..-TPSKGNLA.AHAA.TPAAAVPTTASATSTRRSaaaaaaaaaaaAAAAATPHA.....AGGTA........AGQTPAAAQgPAA...................................AGGRGSAADGSPAAGGG...GAAA.AAGA.S..AaaAKA.GET.PAAAAA...................................G.AAAAaaaaaaaddgversaldeidfyqdhccsvcllpkvtasssnpffycarC---Gvtvhrmcygvpl...............................................................eclpaalrpdlqqQQQQQ.QQQQQQQ...QQQQQETSGSSLK.................................................................................................................................................RLKQTPGVQD.........................NASSNSSSSSSN.SSSTSARTAGASA.---DGRDSSSSSSS-------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------sstpvtpaaipr..............................................................
U6GL42_9EIME/177-474               ..................taataaataaneaaaqpls-------------------------------------------------.---------------------------------------.----..................----------------RC.GFDKDNHLEDE.........DAAAERSS..SSSSSNSSS.SSNS.SSSSSSSKGKGASNVLNAv........eiVKQQETGLS.....PPAAAaataaaaaTAATPAAAA.AAA...................................AGQQGKAATAETTPSTA...---A.TAAA.A..A..TAA.AAA.PRLAARsfli...........................ldepC.KGTA................................................PNCGAallgallealsavkaqgvicthlhhelss..............................lglsfpnnsvkfkqisprrfysnqqqqqqQ---Q.QQQGQKQqqqQQQQQEQQELAAE.................................................................................................................................................GNSCQPPQDV.........................YTSPSSSSPPSS.STSSSTTTTASSS.TSTTTS----SSS--------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------litkdedke.................................................................
Q9VJT7_DROME/7-369                 ...........................asvllhketi-------------------------------------------------.---------------------------------------.----..................------------------.-----------.........--------..---------.----.------------------...........---------.....-----........-------PA.TPV...................................VSTDTASVVGVGVGGGG...GAAA.GAGG.G..A..GGA.GGL.LGDVVS...................................G.LGGGlvneseayaglmkdadklk.........lmllawnyqnstavrngtegP---Dlsvvgglwaqyqnalaqnaaaaaa........................................asgkmdsslspvprqdahspmetqDETNS.SGQKEED...EVSEDDSDDKLDEklatthdperlkafnmfvrlfvdenldriipiskqpkekiqaiidscarqfpefsdrsrkrir...................tylkscrrnkktrdgwenttrptpahltsvqaeqilaiacenesmnakrmriglepithavpaPGSAVAAAA-.........................AAAAAAAVVAAT.SSSAGGTSTTAAGnATATCGMGG------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------vgdatgltsaaaaalpfvsa......................................................
U6KMX8_EIMTE/132-512               .......................avacvafkpqqmea-------------------------------------------------.---------------------------------------.LQQQ..................QQQQQEQQQQQQEQQQQQ.QQHEQQQIPDG........vASGCRDENvcQRSSGNSAS.SSSS.SSSSSSSSSSSGSSSSSL...........CELQDMVLLnvfraASGLIe......wSAPNPAAAA.AAAaga.............................aatTGASGAAAEGAAGAGTG...AAAAgARAA.A..A..ATA.AAA.PEAAAKlgrpsphllqqlqvaalaiwferqnvkikllgaplG.----................................................----Aplgaplgaplgaplgaplglgeapseveas............................rcsssskdpllllllqqvkapnedklrvssSSSSS.SRWGRRS...SSEQQEEAAAAVKalglhaireaav.........................................................................................................................gpfaadlllpsvH--------CvleidgpnhfikppssssssssgkhSRSSSSSGSSSK.SRSSSSSRTSSSS.SSSCGV---------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------wgsaaigek.................................................................
U6MB75_EIMMA/1209-1459             ....qhqqqqqqqqqhasgklaaateamevctpppqq-------------------------------------------------.---------------------------------------.----..................------------------.-----------.........--------..---------.----.---------QQQQQQQQQ...........QQQQQKKQG.....TSASK........DQGGQSTTA.AAT...................................GGGPAAAAAGAEPKG--...TVAA.ATEAtA..A..TAA.AAA.AAAGDT...................................-.EMGV................................................DGDRSspsrdefltprkgkhyrqitlvkyhddpnk...........................nkgygyvdfesheaavaalqrfnlsqqqhnqQQQQQ.QHEQQQQ...HEQQQEQQEESG-.................................................................................................................................................-DAQQTDKAK.........................QDSSSSSTTTTT.TTTTSNSSSSNSS.SSNSSSSSSSS----------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------ssnskl....................................................................
U6LTR1_9EIME/130-444               qqqqqqqqqqeqqlscavggrlghclaalafqrvfel-------------------------------------------------.---------------------------------------.----..................--QQRQQQDEEEQQQQQE.DEQQQQQQQQQqqqlwaplaELMFFGSR..SRSVWERQQ.QQQQ.QPCSDSSSSTTTTTTITS...........TSSSSSSSS.....SSGMC........LDWRLWVSV.AAV...................................AAFPA-AARAADVPSRG...GRRQ.LEGH.H..S..KAVaAAR.PAVLLF...................................G.SRVL................................................AAAAA........................................................................................ACSSS.SSSSGSS...SSSSREFAAKCGEgalqllaiwleaaevqdvcvedfaaa.............................................................................................laaavaafyssaaltdcliaalprlpAFVGLCGVQA.........................GAAGAAAADDSS.SSSCSSSCSSSCS.--SSG----------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------rqplaaaagpaet.............................................................
U6LPV0_9EIME/671-969               ............................gvimkrdsi-------------------------------------------------.---------------------------------------.----..................METDLETEKETDMETGKE.TEKETEEETDM.........ETEEETEK..ETDLETKKE.TGEL.QPLQQQQQQQQH-PHRRP...........QQQQQQEQQ.....QQQQQ........QQQQQQQGV.SGVsplalllpkkngidffagnridcssgkirlllllqF---GLRKAAAAAAGAK..aGAGT.AAAA.A..A..GKG.AAA.AEEGEN...................................G.AAAA................................................PAAAAaaaarsrrgvvf................................................................tsprngskaaaaA----.-------...------------Erdkvrraqmteeeiqkqk............................................................................................................kwrekiqraerggtaadtpPAAAAAG--A.........................GAAAAAKKKKKKrSSSSSDSSSSSSSsDSDSDS---------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------epstcvgyykd...............................................................
B4HXF2_DROSE/5-361                 .............................rlretipa-------------------------------------------------.---------------------------------------.----..................------------------.-----------.........--------..---------.----.------------------...........---------.....-----........---------.TPV...................................VSTDTASVVGVGVGGVG...GGGA.AAGA.GggA..GGA.GGL.LGDVVS...................................G.LGGGlvneseayaglmkdadklk.........lmllawnyqnstavrngtegP---Dlsvvgglwaqyqnalaqnaaaaaa........................................asgkmdsslspvprqdahspmetqDETNS.SGQKEED...EVSEDDSDDKLDEklatthdperlkafnmfvrlfvdenldriipiskqpkekiqaiidscarqfpefsdrsrkrir...................tylkscrrnkktrdgwenttrptpahltsvqaeqilaiacenesmnakrmriglepithavpaPGSAVAAAA-.........................AAAAAAAVVAAT.SSSAGGTSTTAAGnATATCGMG-------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------gvgdatgltsaaaaalp.........................................................
#=GC seq_cons                      .................................t............................................................................................................................................................................................ttt..................t..t...........t.................sh.sss...................................sussuhussussssGsu...usus.Asus.u..s..sts.ush.stssss...................................u..tsh................................................s...s........................................................................................t...p.pt..ttp...p.p................................................................................................................................................................ss.............................tsssut...tt.opssssppssssu.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................ssstth....................................................................
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