GenomeNet

Database: Pfam
Entry: Sporozoite_P67
LinkDB: Sporozoite_P67
Original site: Sporozoite_P67 
#=GF ID   Sporozoite_P67
#=GF AC   PF05642.10
#=GF DE   Sporozoite P67 surface antigen
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_8657 (release 8.0)
#=GF GA   28.00 28.00;
#=GF TC   28.20 28.30;
#=GF NC   27.90 27.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10024569
#=GF RT   Linear peptide specificity of bovine antibody responses to p67
#=GF RT   of Theileria parva and sequence diversity of
#=GF RT   sporozoite-neutralizing epitopes: implications for a vaccine. 
#=GF RA   Nene V, Gobright E, Bishop R, Morzaria S, Musoke A; 
#=GF RL   Infect Immun 1999;67:1261-1266.
#=GF DR   INTERPRO; IPR008845;
#=GF CC   This family consists of several Theileria P67 surface antigens.
#=GF CC   A stage specific surface antigen of Theileria parva, p67, is the
#=GF CC   basis for the development of an anti-sporozoite vaccine for the
#=GF CC   control of East Coast fever (ECF) in cattle. The antigen has
#=GF CC   been shown to contain five distinct linear peptide sequences
#=GF CC   recognised by sporozoite-neutralising murine monoclonal
#=GF CC   antibodies [1].
#=GF SQ   19
#=GS Q4UCF0_THEAN/1-260       AC Q4UCF0.1
#=GS B4Q5H9_DROSI/2-374       AC B4Q5H9.1
#=GS Q27040_THEPA/297-709     AC Q27040.1
#=GS Q27040_THEPA/142-298     AC Q27040.1
#=GS B4JLF1_DROGR/275-521     AC B4JLF1.1
#=GS B4KEJ9_DROMO/12-376      AC B4KEJ9.2
#=GS Q4UCF0_THEAN/318-454     AC Q4UCF0.1
#=GS A0A0Q9YV25_9COXI/86-335  AC A0A0Q9YV25.1
#=GS Q4UCF0_THEAN/449-917     AC Q4UCF0.1
#=GS U6GPL3_9EIME/3-285       AC U6GPL3.1
#=GS Q27040_THEPA/1-145       AC Q27040.1
#=GS U6K223_9EIME/457-736     AC U6K223.1
#=GS U6GL42_9EIME/177-474     AC U6GL42.1
#=GS U6KMX8_EIMTE/132-512     AC U6KMX8.1
#=GS Q9VJT7_DROME/7-369       AC Q9VJT7.2
#=GS U6MB75_EIMMA/1209-1459   AC U6MB75.1
#=GS U6LTR1_9EIME/130-444     AC U6LTR1.1
#=GS U6LPV0_9EIME/671-969     AC U6LPV0.1
#=GS B4HXF2_DROSE/5-361       AC B4HXF2.1
Q4UCF0_THEAN/1-260                  .....................................MNIIHFLLTIPVIFVSGADKMPAGESSRTSKPSPLVTLESAVTQPSKDP.FKTISALSKATKVWKSAVSVSGDSKTVPTPVSEPMITRS.FQEP..................VSQELEFQSDTEINESGS.GSDEDEDD.DDD.........EEEEEDDK..STSSKNGKG.SPKA.QPGVSSSSTSSASPTSPT...........TTLSQTGLG.....PSGSH........AQQDPGVGV.PGVgvpg..........................vgvpgVGVPGVGVPGVGVPGVGgvpGVGV.APGV.G..V..PGV.GVA.PGVGVG...................................AdSSGL................................................PGSGG........................................................................................L----.-------...-------------.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------gagakagkgqg...............................................................
B4Q5H9_DROSI/2-374                  ................................etipa-------------------------------------------------.---------------------------------------.----..................------------------.--------.---.........--------..---------.----.------------------...........---------.....-----........---------.TPV...................................VSTDTASVVGVGVGGVG...GGGA.AAGA.GggA..GGA.GGL.LGDVVS...................................G.LGGGlvneseayaglmkdadklk.........lmllawnyqnstavrngtegP---Dlsvvgglwaqyqnalaqnaaaaaa........................................asgkmdsslspvprqdahspmetqDETNS.SGQKEED...EVSEDDSDDKLDEklatthdperiihlaihlvtsakrvsitsipsfqmfvrlfvdenldriipiskqpkekiqaiidscarqfpefsdrsrkrirtylkscrrnkktrdgwenttrptpahltsvqaeqilaiacenesmnakrmriglepithavpaPGSAVAAAA-.........................AAAAAAAVVAAT.SSSAGGTSTTAAGnATATCGMG-------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------gvgdatgltsaaaaalp.........................................................
Q27040_THEPA/297-709                ...................................pp-------------------------------------------------.---------------------------------------.----..................------------------.--------.---.........--------..---------.----.------------------...........---------.....-----........---------.---...................................-----------------...----.----.-..-..---.---.------...................................-.----................................................-----........................................................................................-----.-------...-------------.................................................................................................................................................----------.........................------------.-------------.----------------------SAPVPSPGAPGIIVRES..........GNRAMDIVQFLGRFKPEPRAYEGERTNVAELKKFLFEELESLVNTLIELKLAIASDFVEITDGLRKNTKDHEARLKLLRGVEFTKRKSVANVVKGFSSLYCVLLMNMNVIKEKTKESEVADGIWKLSTIPDKVANELLLAMEKIVVPPKTPELEEAFEAIEFGFKIAYYATKDILSSIENTVHNLMHAKNYEENFIAQVRNSLRMVPHQMNLTESSFVIKISDMMRRRGTASQDEPAGAGSgvtpgrgssgtgraAGTGGGSLRGLDLSEEEVKKILDEIVKDPSDGELGLGDLSDPSGRSSERQPS-LGPSLVITDGQAGPTIVSPTGPTI------------AAGGEQPPSAPNGTATGPAGTQPEGGEKKEGLIQKLKKKLLGSGFEVASLMIPMATIIISIVH..........................................................................
Q27040_THEPA/142-298                ..................................stl-------------------------------------------------.-------------------STDVSPTIPTPVSEEIITPT.LQAQ..................TKEEVPPA-DLSDQVPSN.GS------.---.........DSEEEDNK..STSSKDEKE.LKKTlQPG-KTSTGETTSGQDLN...........SKQQQTGVSd...lASGSH........---------.---...................................--SSGLKVPGVGVPG--...----.----.-..-..---.AVS.PQGGQS...................................-.----................................................-----........................................................................................LASNT.SREGQAQ...HQQVRDGDGRVIE.................................................................................................................................................PKIGLPG---.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------pp........................................................................
B4JLF1_DROGR/275-521                ..........................irhsdnlrshn-------------------------------------------------.-------------------------------SSSSVTSStYKSH..................SQQQMQQQQQHQQQQQHH.HSSQRRSH.DER.........-VRRRRDS..RTRSRSGSR.SRTR.TPI-DTPPLRRRQGQQST...........RKYRRRESC.....DSSSRs.....rsP-----VER.PPVhvrkpsd.....................vdphtrvYSTAGLLQGKLTLPSTA...AVSA.AAAL.N..A..AAI.SAAgSGVGGG...................................G.VGGG................................................-----........................................................................................-----.-------...-------------.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------ggllptpnyapkipslmslelnappsvlidgppaavqlpkyynpgivnanryaeqqqkrkliwgskknedsank
B4KEJ9_DROMO/12-376                 ........................hketipaapatst-------------------------------------------------.---------------------------------------.----..................------------------.--------.---.........--------..---------.----.------------------...........---------.....-----........-------DT.SSL...................................VGVGGGGGGGVGGGGVG..sGAGG.AGSG.L..V..DIA.NSL.SGGGSG...................................G.GGGG................................................GG--ItneseayaglmkdadklklmllawnyqnstavrngtegpdlsvvgglwaqyqnalaqnaaavaaanskmdsslspvprqdapspmeaqDETNS.SGQKEED...EVSEDDSDDKLDEklatphdperlkafnmfvrlfvdenldriipiskqpkekiqaiidscarqfpefsdrsrkrir...................tylkscrrnkktrdgwenttrptpahltsvqaeqilaiacenesmnakrmriglepithavpaPGSVVAAAAA.........................AAAVAGTSTTSA.SNAATVTCTAADA.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------aglssvaaaalpfvsavgfarstpn.................................................
Q4UCF0_THEAN/318-454                ................................ggkpg-------------------------------------------------.---------------------------------------.--QP..................VSQELELKSDTEINES--.GSSSEGED.DDD.........EEEEEENK..STSSKGAGGkAGKG.QGSVSPGGGSSASQTSPT...........TT-PQSGLA.....SSGSHaq....qsPQQDPAPSK.PSG...................................GGVPGVGVPGVGVPGVGv.pGVGV.APGV.G..V..V--.---.------...................................-.----................................................-----........................................................................................-----.-------...-------------.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------pgvg......................................................................
A0A0Q9YV25_9COXI/86-335             .....ltpndakdfqlvsaslahvnkkykavdltakv-------------------------------------------------.-----------------------A--KPSVSSEEEVSPS.KDAS..................NEDSKDASKDASKDASKD.ASKDASKDaSNE.........DSNEDSKA..SKSASEEKS.SAKE.EPAKKDEDKKTEENKAED...........AKKADEKKDedtqkASSSY........VTAASAVAG.VGI...................................V-ATGFWFSGF-YPSAV...ALLA.KAGL.T..I..PAA.AVA.AQVGVS...................................L.AVGI................................................AVVGVlalg................................................................................yygiSKLFG.SSEVPAT...DEKTKEVENRT--.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------edqkyhddlkakqdltaklaeh....................................................
Q4UCF0_THEAN/449-917                ....................................v-------------------------------------------------.---------------------------------------.----..................------------------.--------.---.........--------..---------.----.------------------...........---------.....-----........---------.---...................................-----------------...----.----.-..-..---.---.------...................................-.----................................................-----........................................................................................-----.-------...-------------.................................................................................................................................................----VPGVG-.........................GATTSSSSTTST.STSTTTTTTTSSGkPSNQGSHGTSPRNAVTRQTDSISGPIPSPGDPRAITGQMgllyssksfvGEGERFAVQFLGDFKPKPRRYEGQGTDAVKLKQFIFEEVKSLVQTLINLKLAIANDFVEISEKLKKKNQNYVPKLKLLKGEQFDTKQKVANVLKGFNSLYFVFFMNLNLAKEVNKPEELAEFLWKLNTIPDKVGREFELAIEKTKGSEKKKELEEAFNSIGLGFKIAQYATNDILSSITNSVYSLIKLKNFGDDFVTEVRKSLQMVPHQKNLNGSAFIVKISEIINKKGTEDQDQTSGSGS..............KGTEGGSLRGQDLTEEEVLKVLDELVKDVSEEHVGIGDLSDPSSRTPNAKPAELGPSLVIQNVPSDPSKVTPTQPSNLPQVPTTGPGNGTDGTTTGP-----GGNGEGGKDLKEGEKKEGLFQKIKNKLLGSGFEVASIIIPMTTIIFSIVH..........................................................................
U6GPL3_9EIME/3-285                  ivktataaaaaaaataaaaagivaaavpqrrkkqqqq-------------------------------------------------.---------------------------------------.QQQD..................QQQQQQQQDQQQQQQQQDqQQQQHQQD.QQQ.........QQQQQDQQ..QQQQQQQQE.QQQQ.QQQQDLLQQQQQQQQQQQ...........QQQQQQQQG.....DSGVHt......lQQRHPATAA.KAA...................................ATATAVAAPALGAAAAA...AAVA.AADA.A..V..LAV.AVV.VTVATP...................................A.AGAVaaavaa....................................aaaaisP---Gpllcvllsklefspphnllpeaaaaaaaaa............................tvaaaaaaaaaaklprnitnynctgsnsnsNSSNSnSSELQQQ...QQQ----------.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------pqqkhhhlqqq...............................................................
Q27040_THEPA/1-145                  .....................................MQITQFLLIIPVLFVSAGDKMPTEEQPFPSRLGPLVTLESAITQPTAVYtMRTVGNVAKAAKAWKSAVSSSDVSTTIPTPVSEENITST.LQTQteevpaasgsdsytvtnlVQTQSQVQDNVKQQQDTK.GNRSDSEE.ENE.........DS------..---------.----.------------------...........---------.....-----........---------.---...................................-----------------...----.----.-..-..---.---.------...................................-.----................................................-----........................................................................................-----.-------...-------------.................................................................................................................................................----------.........................------------.-------------.---------------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------tls.......................................................................
U6K223_9EIME/457-736                .............................assnnppn-------------------------------------------------.---------------------------------------.----..................------------------.--------.---.........--------..-TPSKGNLA.AHAA.TPAAAVPTTASATSTRRSaaaaaaaaaaaAAAAATPHA.....AGGTA........AGQTPAAAQgPAA...................................AGGRGSAADGSPAAGGG...GAAA.AAGA.S..AaaAKA.GET.PAAAAA...................................G.AAAAaaaaaaaddgversaldeidfyqdhccsvcllpkvtasssnpffycarC---Gvtvhrmcygvpl...............................................................eclpaalrpdlqqQQQQQ.QQQQQQQ...QQQQQETSGSSLK.................................................................................................................................................RLKQTPGVQD.........................NASSNSSSSSSN.SSSTSARTAGASA.---DGRDSSSSSSS-------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------sstpvtpaaipr..............................................................
U6GL42_9EIME/177-474                ..................taataaataaneaaaqpls-------------------------------------------------.---------------------------------------.----..................----------------RC.GFDKDNHL.EDE.........DAAAERSS..SSSSSNSSS.SSNS.SSSSSSSKGKGASNVLNAv........eiVKQQETGLS.....PPAAAaataaaaaTAATPAAAA.AAA...................................AGQQGKAATAETTPSTA...---A.TAAA.A..A..TAA.AAA.PRLAARsfli...........................ldepC.KGTA................................................PNCGAallgallealsavkaqgvicthlhhelss..............................lglsfpnnsvkfkqisprrfysnqqqqqqQ---Q.QQQGQKQqqqQQQQQEQQELAAE.................................................................................................................................................GNSCQPPQDV.........................YTSPSSSSPPSS.STSSSTTTTASSS.TSTTTS----SSS--------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------litkdedke.................................................................
U6KMX8_EIMTE/132-512                .......................avacvafkpqqmea-------------------------------------------------.---------------------------------------.LQQQ..................QQQQQEQQQQQQEQQQQQ.QQHEQQQI.PDG........vASGCRDENvcQRSSGNSAS.SSSS.SSSSSSSSSSSGSSSSSL...........CELQDMVLLnvfraASGLIe......wSAPNPAAAA.AAAaga.............................aatTGASGAAAEGAAGAGTG...AAAAgARAA.A..A..ATA.AAA.PEAAAKlgrpsphllqqlqvaalaiwferqnvkikllgaplG.----................................................----Aplgaplgaplgaplgaplglgeapseveas............................rcsssskdpllllllqqvkapnedklrvssSSSSS.SRWGRRS...SSEQQEEAAAAVKalglhaireaav.........................................................................................................................gpfaadlllpsvH--------CvleidgpnhfikppssssssssgkhSRSSSSSGSSSK.SRSSSSSRTSSSS.SSSCGV---------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------wgsaaigek.................................................................
Q9VJT7_DROME/7-369                  ...........................asvllhketi-------------------------------------------------.---------------------------------------.----..................------------------.--------.---.........--------..---------.----.------------------...........---------.....-----........-------PA.TPV...................................VSTDTASVVGVGVGGGG...GAAA.GAGG.G..A..GGA.GGL.LGDVVS...................................G.LGGGlvneseayaglmkdadklk.........lmllawnyqnstavrngtegP---Dlsvvgglwaqyqnalaqnaaaaaa........................................asgkmdsslspvprqdahspmetqDETNS.SGQKEED...EVSEDDSDDKLDEklatthdperlkafnmfvrlfvdenldriipiskqpkekiqaiidscarqfpefsdrsrkrir...................tylkscrrnkktrdgwenttrptpahltsvqaeqilaiacenesmnakrmriglepithavpaPGSAVAAAA-.........................AAAAAAAVVAAT.SSSAGGTSTTAAGnATATCGMGG------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------vgdatgltsaaaaalpfvsa......................................................
U6MB75_EIMMA/1209-1459              ....qhqqqqqqqqqhasgklaaateamevctpppqq-------------------------------------------------.---------------------------------------.----..................------------------.--------.---.........--------..---------.----.---------QQQQQQQQQ...........QQQQQKKQG.....TSASK........DQGGQSTTA.AAT...................................GGGPAAAAAGAEPKG--...TVAA.ATEAtA..A..TAA.AAA.AAAGDT...................................-.EMGV................................................DGDRSspsrdefltprkgkhyrqitlvkyhddpnk...........................nkgygyvdfesheaavaalqrfnlsqqqhnqQQQQQ.QHEQQQQ...HEQQQEQQEESG-.................................................................................................................................................-DAQQTDKAK.........................QDSSSSSTTTTT.TTTTSNSSSSNSS.SSNSSSSSSSS----------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------ssnskl....................................................................
U6LTR1_9EIME/130-444                qqqqqqqqqqeqqlscavggrlghclaalafqrvfel-------------------------------------------------.---------------------------------------.----..................--QQRQQQDEEEQQQQQE.DEQQQQQQ.QQQqqqlwaplaELMFFGSR..SRSVWERQQ.QQQQ.QPCSDSSSSTTTTTTITS...........TSSSSSSSS.....SSGMC........LDWRLWVSV.AAV...................................AAFPA-AARAADVPSRG...GRRQ.LEGH.H..S..KAVaAAR.PAVLLF...................................G.SRVL................................................AAAAA........................................................................................ACSSS.SSSSGSS...SSSSREFAAKCGEgalqllaiwleaaevqdvcvedfaaa.............................................................................................laaavaafyssaaltdcliaalprlpAFVGLCGVQA.........................GAAGAAAADDSS.SSSCSSSCSSSCS.--SSG----------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------rqplaaaagpaet.............................................................
U6LPV0_9EIME/671-969                ............................gvimkrdsi-------------------------------------------------.---------------------------------------.----..................METDLETEKETDMETGKE.TEKETEEE.TDM.........ETEEETEK..ETDLETKKE.TGEL.QPLQQQQQQQQH-PHRRP...........QQQQQQEQQ.....QQQQQ........QQQQQQQGV.SGVsplalllpkkngidffagnridcssgkirlllllqF---GLRKAAAAAAGAK..aGAGT.AAAA.A..A..GKG.AAA.AEEGEN...................................G.AAAA................................................PAAAAaaaarsrrgvvf................................................................tsprngskaaaaA----.-------...------------Erdkvrraqmteeeiqkqk............................................................................................................kwrekiqraerggtaadtpPAAAAAG--A.........................GAAAAAKKKKKKrSSSSSDSSSSSSSsDSDSDS---------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------epstcvgyykd...............................................................
B4HXF2_DROSE/5-361                  .............................rlretipa-------------------------------------------------.---------------------------------------.----..................------------------.--------.---.........--------..---------.----.------------------...........---------.....-----........---------.TPV...................................VSTDTASVVGVGVGGVG...GGGA.AAGA.GggA..GGA.GGL.LGDVVS...................................G.LGGGlvneseayaglmkdadklk.........lmllawnyqnstavrngtegP---Dlsvvgglwaqyqnalaqnaaaaaa........................................asgkmdsslspvprqdahspmetqDETNS.SGQKEED...EVSEDDSDDKLDEklatthdperlkafnmfvrlfvdenldriipiskqpkekiqaiidscarqfpefsdrsrkrir...................tylkscrrnkktrdgwenttrptpahltsvqaeqilaiacenesmnakrmriglepithavpaPGSAVAAAA-.........................AAAAAAAVVAAT.SSSAGGTSTTAAGnATATCGMG-------------------------------..........-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..............--------------------------------------------------------------------------------------------------------------------------------------------------------gvgdatgltsaaaaalp.........................................................
#=GC seq_cons                       .................................t.............................................................................................................................................................................................ttt..................t..t...........t.................sh.sss...................................sussuhussussssusu...usss.usus.s..s..sts.ush.stssss...................................s..hsh................................................s...s........................................................................................t...t.pt...tp...p.p.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ssst.h....................................................................
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