GenomeNet

Database: Pfam
Entry: SseC
LinkDB: SseC
Original site: SseC 
#=GF ID   SseC
#=GF AC   PF04888.10
#=GF DE   Secretion system effector C (SseC) like family 
#=GF AU   Finn RD
#=GF SE   Pfam-B_5525 (release 7.6)
#=GF GA   30.20 30.20;
#=GF TC   30.40 31.60;
#=GF NC   29.90 30.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   1156700
#=GF RT   Theory of RNA-DNA hybridization--I. Stoichiometry at
#=GF RT   equilibrium. 
#=GF RA   Reiner JM; 
#=GF RL   Bull Math Biol 1975;37:225-268.
#=GF RN   [2]
#=GF RM   11580752
#=GF RT   Characterization of translocation pores inserted into plasma
#=GF RT   membranes by type III-secreted Esp proteins of enteropathogenic
#=GF RT   Escherichia coli. 
#=GF RA   Ide T, Laarmann S, Greune L, Schillers H, Oberleithner H,
#=GF RA   Schmidt MA; 
#=GF RL   Cell Microbiol 2001;3:669-679.
#=GF DR   INTERPRO; IPR006972;
#=GF DR   TC; 1.C.36;
#=GF CC   SseC is a secreted protein that forms a complex together with
#=GF CC   SecB and SecD on the surface of Salmonella.  All these proteins
#=GF CC   are secreted by the type III secretion system [1]. Many mucosal
#=GF CC   pathogens use type III secretion systems for the injection of
#=GF CC   effector proteins into target cells.  SecB, SseC and SecD are
#=GF CC   inserted into the target cell membrane.  where they form a small
#=GF CC   pore or translocon [1,2]. In addition to SseC, this family
#=GF CC   includes the bacterial secreted proteins PopB, PepB, YopB and
#=GF CC   EspD which are thought to be directly involved in pore
#=GF CC   formation, and type III secretion system translocon.
#=GF SQ   70
#=GS Y579_CHLTR/141-258        AC O84583.1
#=GS V5UMD2_9BURK/248-569      AC V5UMD2.1
#=GS E3BLV8_9VIBR/115-387      AC E3BLV8.1
#=GS A0A0E2J294_CHLPS/253-437  AC A0A0E2J294.1
#=GS A0A0F5JW55_9BURK/189-522  AC A0A0F5JW55.1
#=GS F8KWQ0_PARAV/481-849      AC F8KWQ0.1
#=GS Q326S9_SHIDS/252-577      AC Q326S9.1
#=GS Q2SC46_HAHCH/70-261       AC Q2SC46.1
#=GS A9MEL8_SALAR/54-442       AC A9MEL8.1
#=GS V5UNB3_9BURK/86-328       AC V5UNB3.1
#=GS Q7NUX0_CHRVO/100-493      AC Q7NUX0.1
#=GS Q6MBE0_PARUW/331-660      AC Q6MBE0.1
#=GS B2VEG7_ERWT9/314-630      AC B2VEG7.1
#=GS A0A068Z5M4_9ENTR/325-655  AC A0A068Z5M4.1
#=GS E3BEJ7_9VIBR/81-462       AC E3BEJ7.1
#=GS A0A078L7Q8_9CHLA/388-728  AC A0A078L7Q8.1
#=GS F9T791_9VIBR/268-367      AC F9T791.1
#=GS A8T5J9_9VIBR/114-395      AC A8T5J9.1
#=GS I0DTZ4_PROSM/217-539      AC I0DTZ4.1
#=GS F9T791_9VIBR/113-291      AC F9T791.1
#=GS C5B9R1_EDWI9/106-478      AC C5B9R1.1
#=GS Q7VWI4_BORPE/80-395       AC Q7VWI4.1
#=GS A0A0K1QPJ8_PSEFL/260-585  AC A0A0K1QPJ8.1
#=GS C0AR44_9ENTR/1-233        AC C0AR44.1
#=GS E0WV27_9ENTR/309-638      AC E0WV27.1
#=GS W8UB45_YEREN/313-677      AC W8UB45.1
#=GS K8WXI4_9ENTR/251-591      AC K8WXI4.1
#=GS Q7N0X3_PHOLL/112-388      AC Q7N0X3.1
#=GS B4EYC8_PROMH/367-716      AC B4EYC8.1
#=GS A0A097QK38_9VIBR/88-477   AC A0A097QK38.1
#=GS Q2NVH6_SODGM/320-652      AC Q2NVH6.1
#=GS V5UNB3_9BURK/313-473      AC V5UNB3.1
#=GS I9KYA1_9RALS/67-388       AC I9KYA1.1
#=GS W0HSL4_9ENTR/101-257      AC W0HSL4.1
#=GS W8X8L7_CASDE/76-406       AC W8X8L7.1
#=GS Q1MP65_LAWIP/119-314      AC Q1MP65.1
#=GS G2GWP8_9ENTR/97-485       AC G2GWP8.1
#=GS SSEC_SALTY/93-482         AC O84947.1
#=GS D2UDP0_XANAP/197-530      AC D2UDP0.1
#=GS A0A0A7ELQ6_9GAMM/73-404   AC A0A0A7ELQ6.1
#=GS Q2SH38_HAHCH/68-373       AC Q2SH38.1
#=GS A0A0F5K5K9_9BURK/102-421  AC A0A0F5K5K9.1
#=GS I6HI54_SHIFL/311-589      AC I6HI54.1
#=GS D4C1Y8_PRORE/310-670      AC D4C1Y8.1
#=GS Y579_CHLTR/255-436        AC O84583.1
#=GS A0A0E2J294_CHLPS/139-266  AC A0A0E2J294.1
#=GS J7U4Y7_MORMO/317-511      AC J7U4Y7.1
#=GS A0A0N0E431_9PSED/254-590  AC A0A0N0E431.1
#=GS BIPB_BURPS/284-616        AC Q63K34.1
#=GS K8WV50_9ENTR/148-346      AC K8WV50.1
#=GS D4ZKM5_SHEVD/98-492       AC D4ZKM5.1
#=GS W8UKN7_YEREN/95-379       AC W8UKN7.1
#=GS W8UQI1_YEREN/15-164       AC W8UQI1.1
#=GS W0I129_9ENTR/320-652      AC W0I129.1
#=GS Q2NTG2_SODGM/104-262      AC Q2NTG2.1
#=GS A6AM44_VIBCY/114-395      AC A6AM44.1
#=GS K8WJ50_PRORE/310-644      AC K8WJ50.1
#=GS O68698_YERPE/106-397      AC O68698.1
#=GS E5Y9W4_BILWA/68-247       AC E5Y9W4.1
#=GS D0Z4V8_PHODD/260-369      AC D0Z4V8.1
#=GS SIPB_SALTY/259-590        AC Q56019.1
#=GS B2VG10_ERWT9/306-622      AC B2VG10.1
#=GS D0Z4V8_PHODD/114-294      AC D0Z4V8.1
#=GS C4K6E2_HAMD5/179-467      AC C4K6E2.1
#=GS A9MF89_SALAR/260-591      AC A9MF89.1
#=GS Q9I324_PSEAE/110-386      AC Q9I324.1
#=GS Q87P61_VIBPA/114-395      AC Q87P61.1
#=GS Q7NUS8_CHRVO/256-580      AC Q7NUS8.1
#=GS G2GYS7_9ENTR/309-641      AC G2GYS7.1
#=GS G8Q409_PSEFL/262-588      AC G8Q409.1
Y579_CHLTR/141-258                   ...................LMGLIMTLLAQASAKSWSSSFQQQNQAIQNQVAMAPEIGNAIRTQANHQa.......qaTELQA...QQS........LIS...GITNIVGFAVSV...GGGILSASKSLGGlKSAAFTNETASAT.......TSATSSLAKTATS--------.....-------..............-----------.--.------...............--------------.---------...--.---.-----.-.-.------....................................................----------.--.----------------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------ald...............................................................................
V5UMD2_9BURK/248-569                 ...................LMGLFAKLLGDSAVKGIEEDMKFFDALRKTRENDMQRQNEEYRKKVEKA..........GFLGK...LFG........VIG...KVVGAVLAVVGV...LGAVFTGGASMAM.TVVGVA-------.......-LLADSVIGAATGFSVVSEAL.....KPVMTHIv...........qpLASLIGDGISGlLE.KAGVPK...............DTADMIGGVVGAVV.AAVVVVALI...AV.AVV.VGGGT.A.-.------....................................................AARLGRMLGD.LA.GDLLKKIVPDLAREALKSGASM...............VTNQFAALATKIG............................................-------...........LKEGNARVFANMLESILKV..............................GELGLGATQTGGQT.....AIGILDKEAADIRADLSVSQE.......VLENVKESVKQAADRFAGTEGVISRLVSQMSDAAKA..KYEAQRF----aln...............................................................................
E3BLV8_9VIBR/115-387                 .................fe--LELAKITDQLKGAQSSIQKQDLSITKERHKKEMDANAEKLIESEAAA..........-KEAQ...KAG........LAS...KVFGWISVAASV...LAGIAMIATGAGA.-VAGVA-------.......-MIVGGVIDATTR--------.....--ILDHA..............-----------.--.--GVDN...............PIA---QKVLMALS.IAVTVVSVV...VT.FGG.AGAAK.L.-.------....................................................-AEVTAKAPQ.TI.LKTVNSLSTKVGNGLT-KVAEI...............NIKAASTSAKAV-............................................-KISSET...........-------------------..............................TDVLANVGQGVSNL.....VSGIKRANVTGIEADLKNSSA.......AMELINAQMDKIKENISKVFESNQHIMDALMRIIQE..RYDVLNSVAQN..................................................................................
A0A0E2J294_CHLPS/253-437             ........kmatdaastaa-------------------------------------------------..........-----...---........---...------------...-------------.-------------.......---------------------.....-------..............-----------.--.------...............--------------.-KTATSAAS...TA.AGS.AAQGA.A.K.-----A....................................................AAGLADDMAS.AA.AKATAGAAGKSGGLFGKALNTPgwkd.......kiarGMNVVKTQGGRAA............................................AFAGRAL...........STSMQMSQMVHA------L..............................TAGIDGIVGGVMGA.....EIAHHQKQAGMAEAHAEE---.......-LKQLSSIQSQYAGQAQQLQEQSQQSFNSALQTLQN..IADSQTQTTS-a.................................................................................
A0A0F5JW55_9BURK/189-522             ..................l--ARLEEMMSKCNIDTLDEQRTMLNGLAEKRQATLQQKSDDYAAKLAEA..........QRLQD...TVG........EIA...KIGGWALTAIGV...GLAIFTGGASLLI.AAAGLA-------.......LMAADAIFKAVTGTSFIDEAM.....KPVMDHAv...........kpMMTWLSKQVSEaLE.SCGVPK...............EKAEIAGAVVAGIA.VAAVMVTGV...VA.VGS.VGGKI.A.S.VVAEST....................................................AKELGEVMES.AV.MRSVKDVMVKLADDTG------...............-VTSMASRAKEAF............................................AALKEQVgl.......dnLEEGQINAIATRTRVGLTV..............................GETGLSGAQAVIDT.....VAAADTRDASMVKASMTRILA.......DKKVISEMLQELVNALSSSASAMRELNSAMSNTLKN..EVSSETFL---lnn...............................................................................
F8KWQ0_PARAV/481-849                 fmkaisdaltklqeqiyli-------------------QNQDASKAKELGKAELDKQLNKLAEQKKQM..........-EDQR...KSGkpglgifnSIM...KVLGPISTVFSV...VIAVLTLGAGAGL.--IGVAVAAAAIA.......YTVADQALTASGKQGVMGYAM.....QALTAAIkaa........ipgP----------.--.------...............PALQMAMDMIIKTV.AIVALTALV...MT.ANP.MVGMT.V.G.-L----....................................................QAIGQATMQS.NV.IQNLVKLMG--GDEMAQQITAM...............VLVTVATVVASLAfmvvtfflqae......................lipfqiaetvaK------...........--------VAKTLVETLTKmaslaekisdailkiarmqlldiaqianqlLSNGLDAAHSAIEIrsqlqQAAKVLAK-AELEADMQVLNA.......MIKLLRKIIDNLTAGMPAEAEAISEIGTLKTHIWQS..QSQITTNIA--na................................................................................
Q326S9_SHIDS/252-577                 ...................LMATFIQLVGKNNEESLKNDLALFQSLQESRKTEMERKSDEYAAEVRKA..........EELNR...VMG........CVG...KILGALLTIVSV...VAAAFSGGSSLAL.AAVGLA-------.......LMVTDAIVQAATGNSFMEQAL.....NPIMKAVi...........epLIKLLSDAFTKmLE.GLGVDS...............KKAKMIGSILGAIA.GALVLVAAV...VL.VAT.VGKQA.-.-.------....................................................AAKLAENIGK.II.GKTLTDLIPKFLKNFSSQLDDL...............ITNAVARLNKFLG............................................AAGDEVI...........----SKQIISTHLNQAVLL..............................GESVNSATQAGGSV.....ASAVFQNNASTNLADLTLSKY.......QVEQLSKYISEAIEKFGQLQEVIADLLASMSNSQAN..RTDVAKAILQQ..................................................................................
Q2SC46_HAHCH/70-261                  ...................LVALLLTIKSKSSNEQIASSQQDIQLNRTKQNQKHDEMLEQIQKSIEAG..........-DKAK...KGG........LFG...KIFGWIANIATA...IAGAVMIATGVGA.----VAGAAML--.......ALAVDSMVGAATGHSLMGEMT.....-------..............------KGIAKgLQ.AMGMDE...............SVANIVAGVVTAAV.TVAVCVGAS...MAsAAK.AGSGL.I.T.RLASS-....................................................PEQMQKI--Q.VA.GAQVKNIAS-------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------atagts............................................................................
A9MEL8_SALAR/54-442                  ...................LSMMMTILILNVFGSSAQSLCQQLERATEVQNTLRDKQVKEYQEQIQKAi.......eqADKAR...KAG........IFG...AIFDWITGIFET...VIGAFKVVEGFLSdNPVEMASGVAYMA.......AGCAGMVKAGAETAMLFGADPd..tcKAIINVT..............-----------.--.------...............SKIQLGCEIVALAL.DVIQIGRAF...MA.TRA.LSGAA.E.K.VLDSGF....................................................GEELAERMAG.AG.EEEIDALAEEFGRQVSENFSRQfesf......dremvELGEMEEESAEFSrtaeknmtrragksftkegvkamvkeaakealekcaqegekfllKNIRKQI...........-LVNVFKKIMSALLRDCSCkslq.....................aircaTEGGNQTNAGVIKT.....EKAKLEKKIEQLIARQQFQDF.......IMEQMEGQKKMEQKRLQALYKGSGAALKDTLDIIDD..YSSVQAKIA--g.................................................................................
V5UNB3_9BURK/86-328                  ...................LVMVASMIAMQALGDTAKSTQTALALLAERQEKLRQEDIQKFREQMDAMt.......adADKAR...KGG........VFG...AIFDWITAAIDL...VVGVVKVVTGVLTmNPLMIAGGIADVG.......AGIAGIGSAVCKTMALIDPKHae.yyEQEAAKW..............-----------.--.------...............GHAQMAFQALGMVV.GFGTSVRGF...LA.SRS.VTKAA.T.R.AFKGGA....................................................GEALTQAVKA.GD.DAAVSAIRARVVSEVSYQVGME...............VGKRVGRSLAQCG............................................TRTARQLa.........rR------------------..............................--------------.....---------------------.......------------------------------------..-----------gfnrmaeqftq.......................................................................
Q7NUX0_CHRVO/100-493                 ...................MIMASTLMTSQMLGDTAAVKSKALDIMSTKQEALRKKEVENIREQMNKAi.......eqQDKAK...KAG........ILS...VVFDWVVAAVEV...VTGVAKMIGGVMTgNVMQAAGGAMDLV.......AGMAGLVKAMANTMALIDPENae.kyQKVADIA..............-----------.--.------...............GKIQLSFEIAGAVV.DVTSAARNL...LV.TKM.IPKVA.G.K.VLKEGA....................................................EQMVSTAIKK.GT.AGAAKNAANAVGKQVADQVATQ...............VAQALGKAAVDAAkattkktvekfaqkftnqml...erftheaiekmvsksvekvikKAVKEGVeltaq.evtkrVVNQVFADVVKATIKATLKapalvv.................sstvrgvAAGAKEIMVGEIEK.....QRAKLQKEIDLLILDQQWLQS.......FFEFYEQEKKEVIKKTRELLDSKSQVIDDGLQAMSQ..AASTQAQIASS..................................................................................
Q6MBE0_PARUW/331-660                 ...................LKATLREIQVHDAEKSKENAKAKFGELADRRLR-AQEQAEKMEKMLKKQ..........-KQMK...SMG........LAM...KIIGPIIAALST...IIGTLIAIASLGTaTAASVA--IIAAGv.....aVGIAMTAYSIADSVTGVTQKIit.afKDALDKL..............-----------.--.----MP...............DSPDWVKSLVKALIvAAVVAVLAV...II.VLA.MASGS.G.-.------....................................................AGAATNAASQ.AV.QQTIRIAVTEAIKQMALQAMIMaims......snalpELVGGILKASGVD............................................KKTQQIV...........----EMVVMAITLIACVIA..............................MAKVGGAKSGGTEQ.....KAADAAEEATKEAAKTVTQRAs.....dALKDFKSQLDNVKESIKKLPETMQQEFKSMMQGFKNldKWDVLNAVAQS..................................................................................
B2VEG7_ERWT9/314-630                 ...................LIALMSKLINQNAGEDLKATSILKQKLSEAAAKDAEKKAQEYETQIRKA..........EEMQK...TMG........CVG...KTLGWIITVVSI...AAAVFTGGASLAF.ATVGLA-------.......LMLGDEINQAINGHSFIQEAM.....QPIMESIi...........qpLMKLLADAFTEiVS.IFGADK...............AAAEMAGQIMGALA.VAILVIAGV...ML.VGV.GISKV.G.G.VLMEKIts...............................................niaSGSLRKIMDS.AA.GQVFKRITQGLSRSFN------...............-------------............................................-------...........VDEVTAARASTYSQAAVTG..............................AGMINTVIKSAGNI.....EAADMMVIAAKAQAKLMKNSA.......MQDLLDSLMNQATDAFSLRLRMVKKIIENIATVAEN..QVQAGRYIL--dk................................................................................
A0A068Z5M4_9ENTR/325-655             ........tlltaqlkktl---------GEDAIKNMRRQQDVIEALNEASRKDQEKKANEADEAQRKA..........EAASK...AAG........CIS...KTLGIIMLVVSV...VATVVTFGTAGPL.-MMAVA--AIGLA.......MAVADVVLEANGCSTLMEMAA.....NEIAKGV..............---------SSlLI.QCGVAP...............EKAKQIANIVGMVV.AAVAFLALS..lLS.VSS.FVKNA.G.T.AVAKTL....................................................-QTGTKMAAN.VL.KSAAKALSDKFINILMKIFS--...............KTGKLTQQFTKFA............................................KNTKEVI..........kLSDVTARRIEMGTKGANMV..............................MGVTKSAVGGGLNL.....YASAQISDMKALLGALIKDNE.......SIQAWVRALEALIKSWAKDFDQHSTDFDNMLTATNE..SGRTKANLMK-s.................................................................................
E3BEJ7_9VIBR/81-462                  ..................i-VMMATNLGLKALGDTANSAAKSLKIKTDAQEVARNRQVKEFQEQLAKQi.......eqNNKAH...KGG........IFG...AIFDWIVGAVEA...VIGAFKMLEGVAR.VAVGDVSGALDIAsgaayltAGFAGMVKAAAETAILCGADKd..kcQDVINVA..............-----------.--.------...............SKVQLGAEIVGMAC.DIFQAGRAI...SA.TRG.IATGT.E.T.AMKE-A....................................................APKLIESIGK.GS.TKEIATVAENVGKQVSEQVGQQ...............VMQQLMKEGAEQSgqiskalakafsed...............airelvtnavketaeQAIKKGVtltae.eltkqVSKNVSQEVFKAVFKACTYtsle.....................ivratAGSSKAVTSGAIGI.....EKAKLQKQIEELILKQNFMEF.......CYEWYNKAKEQQTKSIKDLFDKQGDAVSGASNVISQ..TGSLQARIAT-s.................................................................................
A0A078L7Q8_9CHLA/388-728             ...........elktilfq---------------SLEADSAAAKRMGDANLSLEKEKAELQLKNLEENk.......veMQKQK...DLQ........LAM...KILGPILIVLSL...IIAALTGGAAGFViAAVMAT--ITLVEqtt.ggiNKMFEAISTAIQNDPNIPPEH.....KEAVKII..............-----------.--.------...............VKVLMVATIVAA--.-AVLTGSGI...SA.AGS.ALAGL.Q.A.T----Itglqlgvssllg...........................sqvivdilkaagvSEDARQIVSM.VI.GMVLMIVISIVGMRAMKAVQD-...............LPEQVSAAAQKFK............................................DIIKNISdkipqirdafkAVFASMAQYQSRLGPMFSL..............................IQTTLQMSTSIVNA.....ISNFSKAEAALSKAEI---EA.......AIEEIEALIKQLKKTINKFMQQATSAAED-------..-----------lekegqfsrsi.......................................................................
F9T791_9VIBR/268-367                 ............aaktlst-------------------------------------------------..........-----...---........---...------------...-------------.-------------.......---------------------.....-------..............-----------.--.------...............--------------.---------...--.---.-----.-.-.------....................................................----------.--.----------------------...............-------------............................................-------...........---------------AVKVtrt.......................vaetVDTAANLGSSAADI.....ANGVNQSKVANIQADLADIRA.......EMTLDQSVIDKLKEEIENILQGFQELMEIIMQMIQA..KGETMQTVLN-r.................................................................................
A8T5J9_9VIBR/114-395                 .................fe--LELAVIMEKLNSTQNQLKIKEVEAVKAKHQQEMDANQEKLKESEAAA..........-KEAQ...KSG........LAS...KIFGWVSAVVSV...VVGAVMVATGVGA.----VAGALMIAGg.....vMGAVNMVLQEPAVQEAMKEAG.....-------..............-----------.--.------...............VNVDVLNKVMMALE.ITVAVIGAV...VT.FGG.LAAGG.V.A.KL----....................................................AAKGASQIAQ.KV.TDISTKVAANMTKVAD------...............----MGSKTAT--............................................-------...........----TMAKSIRYSAETV--..............................-DLTTNIGQGTSQA.....VHSSHNANVTKIRADIEGLRA.......ETTLSEAVIDKLKEEIAKLMSDFQELMSVIMQMIQA..KGETMKVVMS-r.................................................................................
I0DTZ4_PROSM/217-539                 ...........alltmlta---SLKKAMNENSIRNMKEQEEVMAKISEASRKDSEKKAKEAEEAQRKA..........DAANK...AAS........CAS...KIFSYVMLAVSV...IATVATFGAAAPL.---TLAVAAIGIA.......ISVTDIVLEETGNASLMQMLA.....TEISNVV..............---------TDmLI.SFGMSA...............EEAKKIGSIVGMVV.AAVAFLALS...LV.SMSsFVKNI.A.N.TV-KTV....................................................VKIAANTLKT.VV.KSTLKAMANTIVNL--------...............-VKNLLSKIKTLG............................................KAADDMVv.........lTKFTKLADAAEELQSTV--..............................-KTANQVVRKARDI.....KNVAKAVDRTHEQADSIKDTA......kAVDKLHEQADSAKHAVK-TVNQVNEQADGIKDA---..-----------vktvdkvhqqad......................................................................
F9T791_9VIBR/113-291                 .................fe--VELAALTDKLKSAQNKLKIEEVKVAKAKHEQEMAENLEKIKESQEAA..........-QEAK...KSG........LAS...KIFGWISAVASI...IVGAIMIATGVGA.----AAGALMIAGg.....lMGVISQVTQMPEVQKAMEAAG.....-------..............-----------.--.---VD-...............--VKAFGYAMMAIQ.GALAIASAG...VA.IGN.IVNAL.K.G.AVDVAAkt...............................................lstAVKVTRTVAE.T-.----------------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------vdtaan............................................................................
C5B9R1_EDWI9/106-478                 ...................MVLAASLLGVKALGDNANLKALALKIREQGAENLRLRQNEDLRKQVDKAv.......edQAKAQ...KAG........IFS...AIVDWIVSIAEV...VSGIGKLLIG---.---DFAGGAMDVA.......AGCSGLVKAACETLALIDKDHad.kyQAIADVA..............-----------.--.------...............GKVQLAFELAGMVV.DLVSVGRGV...MA.GKS.IAKAA.E.T.AMEGAA....................................................GEALHNAVTE.GS.EEAIKAAAKEIGKEVAGQVSEE...............VIRNLAEQSGRFLgqgpllkalskea.................iekmvtqavetavkNALKSGGdisle.altkqVVKEVQRAVIKAIIGACITsvanna.................ksttratLQGTNGIYQGVITK.....ERAELQKVIQQLMNESSFLQF.......MLDEFEKVKKNAQENISNLMDGAGKALSSAADAQQK..SGAMLSSIAAN..................................................................................
Q7VWI4_BORPE/80-395                  ................lad---LLRVLRSRAVDGQLATARENLQDAQVKAKQNTQAQLDKLDAWFRKA..........-EDAE...SKG........WLS...KVFGWIGKVLAV...VASALAVGFAAVAsVVTGAAATPMLV-.......LSGMALVSAVTSLADQISREA.....------Ggp.........pisLGGFLSGLAGRlLT.ALGVDQ...............SQADQIAKIVAG--.LAVPAVLLIe.pQM.LGE.MAEGV.A.R.------....................................................LAGAGDATAG.YI.AMAMSIVAAIAVAAINAAGTAG..............aGSASAIRGAWDRA............................................AAVATQV...........-------------------..............................LQGGTAVAQGGVGV.....SMAVDRKQADLLVADKADLAA.......SLTKLRAAMEREADDIKKILAQFDAAYHMIAQMISD..MASTHSQVSAN..................................................................................
A0A0K1QPJ8_PSEFL/260-585             .................rl---KIIELLGESAQNKEELNQELFLELQAKLQEKMQLESEKYLEEVRKA..........EALQR...TMG........CIG...KIVGALVAIATI...AAGVLTVNPVLIAvGVIGAA-------.......VMIADEVVKELTGVSFMAEAM.....KPLMTVMq............eAIQFFTDLYTKaLV.AFGVDS...............ETAKEIAQIAGMIA.GIAATIAAI...AL.AAI.VGVQV.V.G.PM----....................................................IGAVASRLAS.VV.AQAAPAAVQ-AMKQVASSVG--...............--NTLTQMLTQIR............................................SLVTKGA...........-DAVSLARYTSNLEIAQAL..............................TEFGGVAAQGVLGV.....RSGVHQAQAAEHLADVKVRMA.......ISEEITSYLTRLVEDYGKAMQDRTRHIEHVFADMQR..SHSV-------slqmvr............................................................................
C0AR44_9ENTR/1-233                   ................mal-------------------------------------------------..........-----...---........---...------------...-------------.--LGVAVVMMVASv.....sLMVADEIYQAITHKSFMEEAM.....APVTKAVselidklvdaitnaLEDCFNASSAYiLS.KMGISKeaiekmiqeskdrikEKIRMAVKIVVSIG.LFVGGVALS...CV.AGP.AGSAV.A.S.VAKKIFteqi............................................kmilKKILNDYLEA.ML.GKMIKEIIMETLKDILKSITKL...............LTKDLA----QF-............................................------G...........---------LNALNRILLI..............................SRLITAAVSNIINI.....YTALITDAIIRAVADSKKTT-.......------------------------------------..-----------syir..............................................................................
E0WV27_9ENTR/309-638                 .............igmfie-------TNNNASVEKLNNNRDRIEKIQLANINELKVKEQEATEAAEKA..........AKLGK...IGT........CIA...KVLTYLIVAVSV...IGAVFTAGASLAI.---GIA-------.......LLVTDSVMEAAGVESLSSRMM.....SPLMTEVi...........qpAIKWLTEAFVKiLK.ETGLGDli...........nkAAGKDITEIIATAL.AAVTVIIGM...VV.LMV.VAKVG.G.S.FI----....................................................AKQLGPMFTK.IM.SKIATSAFATAIKNFGQNISKF...............VIKKIPEKLKEWA............................................TQLNEFI...........---------LKTLINGNTIayt........................kmsLTVANASVKAGFDI.....SKGVSDKYIYDLRASMMMIEK.......ISEILQELSSEPLKKFMESFDVNNVMTKTLYDSINN..THKTAQAIL--a.................................................................................
W8UB45_YEREN/313-677                 ...................LMALMSQLINKSSSDDLLATAELKQKLAEAAAKDAEKKAQEYEQEVRKA..........EEMQK...TMG........CIG...KVLGWIVTAVSF...AAAAFTGGASLAL.AAVGLA-------.......LAIGDEISQAVSGRSFMADAM.....QPLMDAIv...........kpLMEMMGKMFSAiLQ.AYGVDK...............ETADMVGQILGAIA.AAAVLVAGV...MV.AGS.VMSKL.F.G.VLMKKIgadv............................................aqeaGKTMAKNVAV.EVeKEVVKDVTKNVVRTAVKEVAEE...............VAQEVAEKATKSTmqrlmd...............................salgqvlKRLSKGLgr......slgADELQMAKVSNYSQKAVVG..............................LNVVNTSSQAAVGI.....VAANMLLEASKIRAEMMKDAA.......LQDLLNEMMTRAIDSFTHRMETVNEIVRNIAVVAEN..QAQAGKYITKQ..................................................................................
K8WXI4_9ENTR/251-591                 ..................mLTAQLKKMMNEDSLRSLKEQESVMEQISTASRKDSENKAQEAEEAQRKA..........EDASK...SAS........CAS...KTLSYVLLAVSV...VATVASFGSAAPL.---TIAIAALGIA.......MSVTDIVLEETGQGSLMQKMA.....-------..............--GVISHVMTDvLI.CFGVEA...............EQAKQIANILGIVI.----AAAAF...LA.IGF.LSSSSlF.K.N-----....................................................MQSTVTNMAK.TI.SNHTKNIIQGAIKVLPKALIVG...............VVKLLAKKSPDLAk..........................................lSKLLEGA...........NKSQKTTQFIEKSTKALKSqktlashie............vgakatgiaVSVVSSATSGGFRL.....YAGAKNQDLKTALANMTLNSD.......TIKALDELLETLIKTLSDKFEQMNDIFTGMLLSLKQ..TDQ--------qktnsi............................................................................
Q7N0X3_PHOLL/112-388                 .................ie--INLGELTSKLDRIQTSLKIQDIQRARQQSLQKMEENQQKIKEAENSA..........-KEAQ...KSG........LFS...KIFGWISAITSI...VIGAIMVATGVGA.----VAGALLIVGg.....vMGVVSQGLQQAAQDGLISKET.....-------..............-----------.--.------...............--MKWLGPVITAIE.ITMAVAAAA...VS.FGG.SAAGL.I.A.KM----....................................................GAKMGSKVAE.MT.AKMAVKAAEFSAKAAG------...............----TAANTTSRG............................................LRVAMQV...........-------------------..............................GDSGVDVTNGAAQT.....TNAAFQSKAANRQADVQLSRS.......ELTAFQAVMDRLKEELSHLVESFQNVMEMIFQMLNA..RGDMINNLAS-r.................................................................................
B4EYC8_PROMH/367-716                 ...................LLSKTRELTLKVMLHRSESEQKLFNEMQEVTEKSLKDKVEEQKSLIKKQ..........EEIQF...WAG........IGL...KILGGLLTLVAG...VSSIFTAGSSMVL.--IGVATTLFVADa.....gLTIADEVYQSIHNKSFMDEIM.....QPISDAVmeaid....kvsdfLVSLVNSSLDG.LK.ELGLDKkiiee....mknsiqDKLKMATKILVTVV.LFVAATALS...FV.IGP.AMKGI.S.D.AVNKISnqqi............................................rqilKKVLNDGLEA.VL.GKMIKDIIIKALEEALEKIDKQ...............LAKEISKKAS---............................................-------...........----------IMLNRTVVA..............................SKLTNSAATNTVNI.....YGSVIASKIIQSIAGSKKLTA.......VLDIIQKLMDKIMETYHENIDSITDILKNLSDKSSV..SNKLKS-----dmirn.............................................................................
A0A097QK38_9VIBR/88-477              ...................MVLMAANLGLKTFGDTANAAAKASRLMTDTQAVLRDQQVKEFQEQLAKRi.......eqAEKAH...KGG........IFG...AIFDWIVGAVEA...IVGVFKLIEGAARiAVGDVAGGALDMAsgaayltAGIAGMVKAAAETAILCGADKe..kcQKVIDVA..............-----------.--.------...............GKVQLGAEIVGMAL.DIFQAGRAI...SA.TRS.IAKGT.E.T.AMKE-A....................................................APKLVESIGK.GS.TQEVTNIAQQVGKQVSEQVAEQvskqlmsgvskgveqV-----------Aerggqiakslgkafseeaiq....qlvtksvekaataaiekgaqI-----Taqe....itkqVTTMVRNEVIKTVIKACTYtsld.....................lirasAGSGKAITSGIVTE.....EKAKLQKQIEDLILKQNLMEF.......CYDWYDKAKEQQSKTIKDLVDKQGDTLDGASKVINE..TGMLQARIAT-s.................................................................................
Q2NVH6_SODGM/320-652                 ...................LLAVINELIGKSASEKLEASAELNKKLSAASIKEAKERAADFAAKQAKA..........EEMQK...TMG........CIG...KIIGWIITVVSV...AAAAFTGGASLAL.AGVGLS-------.......LAIGDEIGQAITGKSFMQEAMga.ilDPIMKGIi...........qpLMQFYANLFSKvLE.GLGLDK...............GLADTIGQIMGAIQ.AAVMMIAAV...MM.AGS.LVKSI.A.S.KIGSTMiv................................................kaGMAFAKRMLQ.NM.G---KKVAETLGKKLG------...............-LNTLTSFAKKSG............................................TRLAKFS..........pI----NKGNAATVQKVVVV..............................ADVVNTTAQAGGNI.....AVAALQSSAAQDKADLLQAMA.......TQELLKKMMDEAVNVFTHNLATMNEIMNQMSQVGLQ..DQQTKRFITQQ..................................................................................
V5UNB3_9BURK/313-473                 ...........qlarrgfn-------------------------------------------------..........-----...---........---...------------...-------------.-------------.......---------------------.....-------..............-----------.--.------...............--------------.---------...--.---.-----.-.-.------....................................................-RMAEQFTQQ.MV.EQMVSRAFDNVVKSTAKQVAKG...............VAVRAADVTRAFG............................................----S--...........---QAASQGRRAILRGMWSlsav......................lrgaMVAGRDMTAGAIGI.....QRAKLQREARDLQVETTWLQF.......LMEMNGDDKRRLAQRMQALSAQQGDAAQTASEAVAS..TGALRIRIAAS..................................................................................
I9KYA1_9RALS/67-388                  .ayqlqlmfadlkrvqsya-------------------SAQAAHNQSNQIEDATKETFDALKRLMEQM..........-DKLAsrdIWD........LVG...AVIGTVFSAIF-...-AGVAIAASGGALtAPVAVTMTVLVGS......vIQMASAISTQKGGPDFSVNKGltegfQQLAEQW..............-----------.--.---MSK...............EDAAKLGTLLAGIV.GTVTIAPALmdaQI.GGS.LLSGA.A.A.--MGG-....................................................ASDKVVAILK.MV.GTLANGIANAIVSGK-------...............AMNSAVKAAEEA-............................................---GRIV...........TGSNAFQKVFTIQNGQIVSg............................aVQGGLGIQRGKDGV.....EQAQRQHDVDMTQAEETALRG.......FTDYLNATFSMTADHQKSMEEVLQEILEKIKDSKED..MQASQTR----lvrs..............................................................................
W0HSL4_9ENTR/101-257                 ..................l-SLMANGLMQTICNKNADSICQQIQRASEVQDVLRARQLKDYQAQINKTa.......eqAEKVR...KAG........IIS...AVCDWIVSGIQL...VMGTLRVMAG---.---DVVGGMATIM.......NGVAGVIKASAETALLCGADK.....ETCAKVI.............lIATLLQTVFGA.MS.MMG---...............--------------.---------...--.---.-----.-.-.------....................................................----------.--.----------------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------smasagnikdagqavrg.................................................................
W8X8L7_CASDE/76-406                  .................mv--DLLRSLRSKSDDAQLATAQKSLESARIKAEKNTEHQLEKIKEWIEKS..........-KEAE...SKG........ALG...KIFGWIGKIFAF...VAAIAAVVAAAAAtVATGGAAAPLLA-.......LAIVGAISATMTLASAISQEC....gGPEIS--..............INSLIQHTVGKfLTdVCGVDP...............KQAENICKIVGGALaIACPVMLAIe.pSL.LGN.MAQSI.A.L.------....................................................MAGADEKTAG.YI.GMALTIAAAIGIGIAMA-----...............VMTGGASAASTAA............................................-QVSNKV...........-LLSSIKTFNTVLASTNVA..............................VSGSTQIAQGGLNI.....SKAQSEEKAQKAMADKKDLEA.......MMLKLQKQMEEGREEMKKIIQQIEESTQLVSKMIAG..TTDNMNQIAMN..................................................................................
Q1MP65_LAWIP/119-314                 ..................l-STLMGSLQLTEQKKNAEKTVNEIKAQNKEQQVKFQEQIKKIEDNIAES..........-KKSG...ILK........FFQ...KLFAVIGAVLGA...IGGALAIAAGAASgNPLLVAAGIMAIV.......ASIDAAMSSLSDGKVSISAGI.....-------..............---------SKaLE.AMGVPA...............ETAQWIAFGIQLAM.IAVTIAIGF...AS.GGG.GAMAG.V.S.KIADMF...................................................sKSQDVAKLAQ.MI.EKASKI----------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------vqiags............................................................................
G2GWP8_9ENTR/97-485                  .................ni---LVMMLIAKFTKDSNTVLSKVITRSSDLQIFLRDQQVEDFQKQIAKAv.......eqGEKAK...KAG........VCA...AVFDWIIGAAEV...VWGVCKMIEGMVE.----LAGTALTGG.......LSAVAGIAALTAGFAYIGAGC.....AGISKGTa............eMCLALGYGDKEqLK.KFIEKE...............GEIQLGFEITAMLF.DLIKGGALI...GV.ARN.MIKPA.LeE.TLKAGTsemlgnlakeagdtitteeveqiintaarfvaqetaelvivdvtksftqaafKEALASATEK.TM.AEVITETAKKSVKEAAEEIAGQ...............IEKK---------............................................-------...........ILQKVMTKVSCKIMKNIVFtwlt.....................ylrffSGSIVTIHNGLLKS.....DSADITEKIQTLILNREFDQH.......KLDIAEKSKQQDQKMLKKIVESYADLTERTFSNNNQ..YALLQTKIA--nsi...............................................................................
SSEC_SALTY/93-482                    ...................LSMMMTSLILNVFGNNAQSLCQQLERATEVQNALRNKQVKEYQEQIQKAi.......eqEDKAR...KAG........IFG...AIFDWITGIFET...VIGALKVVEGFLSgNPAEMASGVAYMA.......AGCAGMVKAGAETAMMCGADHd..tcQAIIDVT..............-----------.--.------...............SKIQFGCEAVALAL.DVFQIGRAF...MA.TRG.LSGAA.A.K.VLDSGF....................................................GEEVVERMVG.AG.EAEIEELAEKFGEEVSESFSKQfepl......eremaMANEMAEEAAEFSrnvennmtrsagksft...........kegvkamakeaakealeKCVQEGGkfllk.kfrnkVLFNMFKKILYALLRDCSFkglq.....................aircaTEGASQMNTGMVNT.....EKAKIEKKIEQLITQQRFLDF.......IMQQTENQKKIEQKRLEELYKGSGAALRDVLDTIDH..YSSVQARIA--gy................................................................................
D2UDP0_XANAP/197-530                 ...................-MAKLQKLMSKSDIDGLDSQRKTMNELSAARQADLQKSADEYAAKVAQA..........QRLEK...IIG........TIA...KIGGWAMTIIGL...GLALITGGASLLI.AAAGVA-------.......LMAADAIYEKETGKSFIDEAM.....QPLMDHTi...........kpMMEWLSKKVTSlLE.DCGVPK...............DKAEIGGAVIAGLV.VATVMMTGV...VA.VGS.AAGKV.A.S.LVADSV....................................................AKEFAECMES.TV.FRSMKDVMAKLADDNG------...............-LKSVVSKVKTFY............................................TEMREQAgl.......drLEEGQIRAITTRGRLGLAV..............................GETGLSGSQGVVNV.....IAANDIKDASIMQAATTRALA.......DKKVIAQILQELATSFSNNLSAMTSLSNTMSDALKN..ETNADIFVLKN..................................................................................
A0A0A7ELQ6_9GAMM/73-404              .............ikeikd--------------STIAANKAELERVQAEQEDLMNEQIDKLNEQEENRldqiekaekaRKKAK...QAG........IFG...KAFGFVTAIATT...IGGMCSLAAGVLSgQPNLIA-------.......AGVALTAAGMCEVAAQICLALg...eD----KA..............-AEILSYTAIA.LT.VIGVG-...............---------LLTYG.AASGAAAGA...AA.GKE.VAKEA.T.EvAVKEGV....................................................KAAAKEAASE.AA.EEVIEQAAKAVVKEISQNVAEE...............VAEEAIERAAKNL............................................---CETM...........-IKKQSDDMIKAAMGRTTWas..........................saASMGAQTGSGIISA.....EQADIQEALNKINLQVQLLESelveneaLVSKLESILQRFIAFIQSQSGTVVDIASILSDAAKN..EMQASLSVL--nn................................................................................
Q2SH38_HAHCH/68-373                  ...................LLLALQSLQVKLDEEGVKSGKEDAKFLAQENKERHKEVMEALQKSINEM..........-EKAK...KSG........MFA...KVFGWIAAAATL...IAGAAMIATGAGA.----IAGGVMM--.......ALAVDQMVGMATGKSAVSELT.....NAIAKGL..............-----------.--.------...............--ANVMGEPANAIV.-ASVIVAAV...LI.IGT.AGAGM.Y.A.SATT--....................................................SAGKAASVAS.NS.SKTASSAAS-AGKTAGAATQAG...............ATASSSSQAATNS............................................--LSKL-...........AQSLSEWPLLHQARNMSLF..............................VSSGAQVGGGAAGV.....DASVHTKEANDAKAEEALVRK.......VIMQNQAGIEQAIEHIKSLTSNSESTLSQMVNYINQ..EQQTNQTLIR-d.................................................................................
A0A0F5K5K9_9BURK/102-421             .................ma--LAMHLMQASFSNAQAGTALAEIKNNSVKLKASQAEQNAHYKKAVESG.........rEAEAK...SGG........VLGffrKLFKATAALAGI...VLSAIAVAATAGA.AAPLLA-------.......FAVAGAIGATISLASEISQAAg...gPPISLSA..............---MLTKMGTA.LAlACGASE...............EDAEKIGKVAGNSM.GVLLAVIDP...SI.LGE.LAGGI.A.A.-L----....................................................-SGASPTVMG.II.T----VVATLAAVALTMAGTNA...............LLKGVEGGNKLVG............................................V------...........LAKMAGLKYGLMVTKGV--..............................AEGAGGIVGGTQGI.....LVARSQFEVDTARADAKAASV.......QTMKLQKQMDDLLEEVRRLFERVEDSYSGATRMLGR..ASQSYQLLA--rn................................................................................
I6HI54_SHIFL/311-589                 ...................MMAQLVTILGKCNEETLKTNMELAKSQQSAKQAELAKETEKSDKIAEKQ..........KRMHK...IFG........ALG...KVLMAVTMIAGA...ISALFTGGVMAIL.FVASTA-------.......LMISDQITKAATGESFMGKAM.....NAVVSEL..............---------AKmFE.AMGAD-...............---ELVASILASIT.MLLATIAAT...VV.LGK.GAKFL.N.N.KF----....................................................ASKIANSILR.VL.S---NHGTSGAGRIMK--MGSE...............ITFRVSLTASGI-............................................-------...........-------------------..............................NNGAYSITSGVYEQ.....QRANISAKLIEIMKDNDF---.......----VKRFMDMIVENYSNTMKTMNAIIKNETEASGM..SMQVGKQILA-h.................................................................................
D4C1Y8_PRORE/310-670                 ...............ltml-TAQLKKVMNEDSIRNMKEQEAVMMKINEASRKDSDNKAKEAAESERKA..........AEANK...AAS........CAS...KIFSYVLLAVSV...VATVASFGTAAPL.---TLAIAAIGIS.......MAVADIVLEETGHGSLMQMLA.....NEISSVV..............---------TDvLI.KFGVDE...............DKAKQIGSIVGMIV.AAIAFLALS..lIS.MGS.MAKNI.V.N.TVKSAAqlllkna......................................gsllkstIKAMPKNLTN.AL.GNMATKTAK-VSDSVADNTDDM..............vKLTKFTKLADKFDdakdtvkt............................tentiakiKKVDTVK...........NPSVAMAKLEVTARGMNAG..............................LTVANAATTGGLNV.....HAASMGTKMKEMLAGMMLNNS.......AIEAITELLNQLIQAMSKNYEQFDEMFVSMLNGLQK..SGQS-------kvdm..............................................................................
Y579_CHLTR/255-436                   ................sal-------------------------------------------------..........-----...---........---...------------...-------------.-------------.......---------------------.....-------..............-----------.--.------...............--------------.--DDVAGTA...TA.VGA.KATSG.A.A.SAASSA....................................................ATKLTQNMAE.SA.SKTLSQTASKSAGGLFGQALNTpsws......ekvsrGMNVVKTQGTRAA............................................KFAGRAL...........------SSAMNISQMVHGL..............................TAGIDGIVGGVIGA.....QVAQEQRMAGMAEARAEE---.......-LKSLNSVQAQYASQAQQLQEQSQQSFNSALQTLQS..ISDSALQTTA-s.................................................................................
A0A0E2J294_CHLPS/139-266             ...................LLGLIMTLLAQASAKSWSSQFQQQNQAIQNQVAMAPEIGNAIRTQANHQa.......aaTEAQA...KQS........MIS...GIVNIVGFAVAV...GGGILSAAKSLGGlKSAAFAKETAGATgs...aaSSAASQASKMATD--------.....-------..............-----------.--.------...............--------------.---------...--.---.-----.-.-.------....................................................----------.--.----------------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------aastaakta.........................................................................
J7U4Y7_MORMO/317-511                 ...................LMGKIADLRNKLAQRKLENDRLIATIQQKTLQDKTDADGAEMAKKIKKA..........ERLQA...---........-LF...KWLGPLLIALMV...ILTALTGGL--LA.-K-ALA-AV-IVV.......VTIISEIVKAAGGPDIMATIM.....TPVTKLVe............vVQKFIKDMAMKiGQ.KLGLPPa............elKKLEEKMEIIAMVL.AVVVVMAVF...AA.AGA.VAGKV.I.-.------....................................................GQVVSESVKE.IL.RQVMV-----------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------evk...............................................................................
A0A0N0E431_9PSED/254-590             ..................a-MARLIELLGDAADRQLQADQELFLDMQAARQEFMRIKSEEYQEEVRKA..........EAAQK...AMG........CMG...KILGWLVMAISA...VVAVVSTVATLGA.-AAPAAGALVAAAvgivgvlASLSDMIVKEATGNSFMEKAM.....KPVMEVFq............kLVKLMADMYSQaLM.ALGVPE...............DKAKIIGAVLGAIA.AVVMVIAAA...VV.GIQ.AAGPV.L.G.SVMNKV....................................................MEKMGDVFSK.MV.PELLKQSLGSLGKSLA-RLAEQ...............LRGLVASST----............................................-------...........-DEVAVGQLKNRLELLLAT..............................VQTAGTATQSGLQI.....KNGIHQKQGAEHLADIRVSMA.......IVDALGGYLEEALETFARLVENNDEQMKRFMAKAQQ..DHSAALQIARN..................................................................................
BIPB_BURPS/284-616                   .................vl--GKLQELISSGNVKELESKQKLFTEMQAKREAELQKKSDEYQAQVKKA..........EEMQK...TMG........CIG...KIVGWVITAVSF...AAAAFTGGASLAL.AAVGLA-------.......LAVGDEISRATTGVSFMDKLM.....QPVMDAIl...........kpLMEMISSLITKaLV.ACGVDQ...............QKAELAGAILGAVV.TGVALVAAA...FV.GAS.AVKAV.A.S.KVIDAM....................................................AGQLTKLMDS.AI.GKMLVQLIEKFSEKSG------...............-LQALGSRTATAM............................................TRMRRAIg.........vEAKEDGMLLANRFEKAGTV..............................MNVGNQVSQAAGGI.....VVGVERAKAMGLLADVKEAMY.......DIKLLGDLLKQAVDAFAEHNRVLAQLMQQMSDAGEM..QTSTGKLILRN..................................................................................
K8WV50_9ENTR/148-346                 ...............ivvp-------------------------------------------------..........-----...---........---...------------...-------------.-------------.......---------------------.....-------..............------KVMDKiLQ.AFGVDE...............KIRKWVNVALEVTI.GVIGAVLSFnpaNI.MSS.VGKAA.A.-.NVTAKV....................................................GSVLSKAVDAlKT.FKAFSAISQKVQQVIS------...............---KAIKLVEPLV............................................AKIQEFV...........---KGGHQASARIGQVTSV..............................TTDVTSVVSTGYSI.....KSAAITRDLEMAQADQDELET.......RLQQIQIMLDTAMKTMAHAFESLFDTKDAARKNIQK..S----------isih..............................................................................
D4ZKM5_SHEVD/98-492                  ...................MVLMATNLSISTFADTANAALKSQKIMSKTQEFLRNKEVDEFQEQLAKAv.......eqADKAQ...KGG........IFG...AVFDWIVGAAEA...IYGAIKLVEGGLRcAMGDVVGGALDIAdgtaylgAGVAGMVKAAAETAILCGADRd..kwQSVIDVA..............-----------.--.------...............SKVQLGCEVVAMAL.DMFQAGRAI...SA.ARG.IAKGT.E.K.AVQEG-....................................................AGKLLETIAS.KS.SEAMTEVAKDIGKQVSDSVANK...............VLENLGKSFEKVAtevaqktektlrqrilsqlv...dafskesieklvtksvenvgkKAIKEGVkitae.ditkqVVKEVRSEVIKAAIKACTCttle.....................ivrgtAEAGNDITQGSIAI.....EKAKLQKKIEELILKEDFLEF.......CHDWYDKAKAEQMKSIKDLINKEGDSLEGASKAISQ..NGSIQAQIAG-s.................................................................................
W8UKN7_YEREN/95-379                  ..................i-MSMAGNLNIGLFSDLCKSIGKQMERATDVQAFLRDKRVSEYQKQIDKAv.......eqADKAK...KAG........IFN...AVFDWIIGAAEV...VYGALKIAEGVLTgDPVAMTSGVAYLA.......AGTAGLVKAAAETAMLCGASKe..kcQEVIDVA..............-----------.--.------...............GKVQLGFECFAMAI.DLFQAGRAI...NA.ARA.VTQGA.G.D.VLAKGG....................................................GEALTDAIKR.GA.TEEIEQLAGQFGKDVCQQVSYDismkameiemveateM----ASAAA---............................................---KQAV...........--KAEMTLVRNITKSFT--..............................--------------.....---------------------.......------------------------------------..-----------hqgieklvsgvtkklaqdaikkgvillygqggctvqq.............................................
W8UQI1_YEREN/15-164                  ...........ggctvqqq-------------------------------------------------..........-----...---........---...------------...-------------.-------------.......---------------------.....-------..............-----------.--.------...............--------------.---------...--.---.-----.-.-.------....................................................------GIEK.LV.SGVTKKLAQDAIKK--------...............---GVILTTEELS............................................QQCTRAI...........-----MKKSVTTILKDIATspll.....................iiqkcSSAAVQINNGQLSV.....QNAGLQKEIQKLILDQDFTQF.......MDEWVERNKQHQLKQLKETSQNAQDSLTKLNDNIRQ..NGMLQVGIA--ns................................................................................
W0I129_9ENTR/320-652                 ...................LLAVINKLIGKSASEKLEASAELNKKLSAASIKEAQENAKEFAAKQAKA..........EEMQK...TMG........CIG...KIIGWIITVVSV...AAAAFTGGASLAL.AGVGLA-------.......LAIGDEIGQAITGRSFMQEAMga.ilDPLMKAIi...........qpLMQFFTNLFSKiLE.GLGMEK...............GLADTIAQIMGAIQ.AAVLMIAAV...MV.AGS.LVKSV.A.Q.KIGSTLiv................................................ktGMAFAKRMLQ.NM.G---KKAAETLGKKLGLNTVTN...............FAKRAGSSMAKFS............................................-PINEGN...........---------AAMVQKGATI..............................ANAVNTTAQAGGNI.....AVAALQASAAEDKADLLQAMA.......TQELLKKMMDEAVNVFTHNLATMNEILNQMSQVGLQ..DQQTKRFITQQ..................................................................................
Q2NTG2_SODGM/104-262                 ...................LLLMVNGLLQEVYAKNADILCQQIQRASDVQEVLRDKQLKDYQAQINKAa.......eqADKVC...KAG........IFS...AVCDWIISGVQL...AVGALRIMAG---.---DVVGGTATIL.......NGVAGILKASAETALLCGADK.....----EVC..............-----------.--.------...............SKIILAATVLQTLF.GAIAMIGGM...SV.AAN.-AKGV.G.Q.------....................................................----------.--.----------------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------amggsk............................................................................
A6AM44_VIBCY/114-395                 .................fe--VELAAITDKLKSAQNELKIQEVKVAKAKHEQEMAENLEKIKESEAAA..........-KEAQ...KSG........LAS...KIFGWVSAVVSI...VVGAIMVATGVGA.----AAGALMIAGg.....vMGAINMTLQEPAVQEAMKEAG.....-------..............-----------.--.------...............INVDILNKVVMALE.IATAVIGAV...VT.FGG.AAASG.V.A.KL----....................................................AAKSASSIAQ.KV.TDIATKAATNMAKIAD------...............-M--GSKAATTTA............................................KAIRYGA...........-----------------ET..............................VDLTVNVGKGTTDS.....IHAANNAHVTEIQADITDLRA.......KMTLSQAVIDKLKEEIAKLMEDFQELMSVIMQMIQA..KGETMQAVMS-r.................................................................................
K8WJ50_PRORE/310-644                 ...............ltml-TAQLKKVMNEDSIRNMKEQEAVMMEINEASRKNSDKKAKEAAESERKA..........AEANK...AAS........CAS...KVFSYVLLAVSV...IATVASFGTAAPL.---TLAIAAIGIS.......MAVADIVLEETGHGSLMQMLA.....NEISSAV..............---------TDvLI.SFGVDE...............DKAKQIGSIVGMIV.AAIAFLAFS..lLS.MGS.MVKNI.A.N.TVKS--....................................................---AAQLLLK.NA.GSILKNTVKSMPKSLM-----N...............ALGNVATKTTKASdsvad..................................gtkaiKQVGETAkn.......tkNXSVAMAKLEVSARGMNAG..............................LTVASAATTGGLNV.....YAASMGEKMKEMLAGMMLNNA.......AIEAITELLNQLIQAMSKNYEQFDEMFVSMLNGLQK..SGQS-------kvdm..............................................................................
O68698_YERPE/106-397                 .................fe--IELGKLVSNLEEVRKDIKIADIQRLHEQNMKKIEENQEKIKETEENA..........-KQVK...KSG........IAS...KIFGWLSAIASV...IVGAIMVASGVGA.----VAGAMMVASg.....vIGMANMAVKQAAEDGLISQEA.....-------..............-----------.--.------...............--MKILGPILTAIE.VALTVVSTV...MT.FGG.SALKC.L.A.NI----....................................................GAKLGANTAS.LV.A----KGAEFSAKVAQ--ISTG...............ISNTVGSAVTKLG............................................GSFA---...........--GLTMSHAIRTGSQ---A..............................TQVAVGVGSGITQT.....INNKKQADLQHNNADLALNKA.......DMAALQSIIDRLKEELSHLSESHQQVMELIFQMINA..KGDMLHNLAG-r.................................................................................
E5Y9W4_BILWA/68-247                  ...........letlaqmi--------SNETRTQATKDGVASIDAKGKERAEINEKKLEEIMDRLDSM..........-KSKG...ILD........VFK...KIFSWVGVIVGA...IASVATIVAGAATgNPLLIAGGAVMLT.......MSINSAVSMATDGKVSISAGI.....-------..............---------AAgLK.ACGVPEd............iaGYVGMACELAITIVgIGLTMGGSF..gSA.ATT.SAQTL.S.-.------....................................................----------.--.----------------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------kvadialkssn.......................................................................
D0Z4V8_PHODD/260-369                 .......sasiakiaemgs-------------------------------------------------..........-----...---........---...------------...-------------.-------------.......---------------------.....-------..............-----------.--.------...............--------------.---------...--.---.-----.-.-.------....................................................----------.--.----------------------...............-------------............................................-------...........----KTATMTTRVIN---Ltt..........................esIDIAINTGKGITDS.....INSKKSANVATIQAEITNLKS.......SMTLSQAVLDKLKEEIAKLIEDFQELMSVIMQMIQA..KGETLQAVMS-r.................................................................................
SIPB_SALTY/259-590                   ...................LMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQEETRKA..........EETNR...IMG........CIG...KVLGALLTIVSV...VAAVFTGGASLAL.AAVGLA-------.......VMVADEIVKAATGVSFIQQAL.....NPIMEHVl...........kpLMELIGKAITKaLE.GLGVDK...............KTAEMAGSIVGAIV.AAIAMVAVI...VV.VAV.VGKGA.-.-.------....................................................AAKLGNALSK.MM.GETIKKLVPNVLKQLAQNGSKL...............FTQGMQRITSGLG............................................NVGSKMGl.........qTNALSKELVGNTLNKVALG..............................MEVTNTAAQSAGGV.....AEGVFIKNASEALADFMLARF.......AMDQIQQWLKQSVEIFGENQKVTAELQKAMSSAVQQ..NADASRFILRQ..................................................................................
B2VG10_ERWT9/306-622                 ...................LMALISQLINQSSSEDLNATAELKKKLSEAAAKDAEKKAAEYEEQVRKA..........EELQN...TLG........CVG...KIFAYVVTAALT...AAALVTGGATLILvAGIGVA-------.......MLAAEEIQTAMTGSSFMSDGM.....QWVMEKVl...........qpLVDLYSKIFTAvLK.EFGVSD...............EKAEMVGKILGAIQ.AVIVMIGTL...VV.AGS.VAKSL.V.S.HLMKSLgk................................................niSSQLLKNMMT.NV.SHITKSFTQGFGRSLG------...............-------------............................................-------...........MGPVQTAQFATRIQSAVTV..............................GTFLNSIAQAGGGI.....VAAHISVKASEARAQMMNDAA.......MQTMLNEIMSRAVDIFTLRMETVNSIVKNISAVAES..QIQAGKYITRR..................................................................................
D0Z4V8_PHODD/114-294                 .................fe--VELAAITDKLKSAQNELRIQEVKVAKAKHEQEMAENQEKIKESESAA..........-KEAQ...KSG........LAA...KIFGWISAVASI...IIGSIMVATGIGA.----VAGALMIAGg.....iLGVVSATIQEPAVQDAMKEAG.....-INIDAL..............-----------.--.------...............QKAIMAFEIAVAVI.GAVVTVGAF...FS.A-S.IAKIA.E.-.-MGSK-....................................................TATMTTRVIN.LT.TE--------------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------sidiaint..........................................................................
C4K6E2_HAMD5/179-467                 ...................LMAEVINLMSESASIDIQNTKKVMEAEFQNNITQMKEQIKKNKEAMEKA..........KTMKE...KMG........CIA...KVIGHVVTAITVlssIAAVFTGGASLVI.AALA-------LG.......LLAADKSLELSGKKSLTARAM.....EPLMKAI..............-----ADGIASrLE.KDGLDK...............NTANLIAAILTAII.LVVALVLVSa.gLA.LKS.VSQLI.S.K.-----Ivpkfis........................................kfigkmSSKTTQLMLK.YG.NYVMQALR--------------...............-------------............................................-------...........-------------------..............................--------------.....---------------------.......------------------------------------..-----------ailhptghaingtgeiisneykgksvdaqaeikrlqferkrinelrqsiespmesisdavvhlkedlsqailralssmqvfv
A9MF89_SALAR/260-591                 ...................LMAMFIEIVGKNNEEGLQNDLALFNALQEGRQAEMEKKSAEFQEETRKA..........EETNR...IMG........CIG...KVLGALLTIVSV...VAAVFTGGASLAL.AAVGLA-------.......VMVADEIVKAATGVSFIQQAL.....NPIMEHVl...........kpLMELIGKAITKaLE.GLGVDK...............KTAEMAGSIVGAIV.AAIAMVAVI...VV.VAV.VGKGA.-.-.------....................................................AAKLGNALSK.MM.GETIKKLVPNVLKQLAQNGSKL...............FTQGMQRITSGLG............................................NVGSKMGl.........qTNALSKELVGNTLNKVALG..............................MEVTNTAAQSAGGV.....AEGVFIKNASEAIADFTLARF.......AMDQIQQWLKQSVEIFGENQKVTAELQKVMSSAVQQ..NADASRFILRQ..................................................................................
Q9I324_PSEAE/110-386                 .................fe--IELAKITGEVENQQKKLKLTEIEQARKQNLQKMEDNQQKIRESEEAA..........-KEAQ...KSG........LAA...KIFGWISAIASI...IVGAIMVATGVGA.----AAGALMIAGg.....vMGVVSQSVQQAAADGLISKEV.....-------..............-----------.--.------...............--MEKLGPALMGIE.MAVALLAAV...VS.FGG.SAVGG.L.A.RL----....................................................GAKIGGKAAE.MT.ASLASKVAD-LGGKFG------...............---SLAGQSLSHS............................................LKLGVQV...........-------------------..............................SDLTLDVANGAAQA.....THSGFQAKAANRQADVQESRA.......DLTTLQGVIERLKEELSRMLEAFQEIMERIFAMLQA..KGETLHNLSS-r.................................................................................
Q87P61_VIBPA/114-395                 .................fe--VELAAITDKLKSAQNELKIQEVKVAKAKHEQEMAENQEKIKESEAAA..........-KEAQ...KSG........LAA...KIFGWISAVVSI...VVGAIMVATGVGA.----AAGALMIAGg.....vMGAVSMALQEPAVQDALKEAG.....-------..............-----------.--.------...............VNVDVLNKVVMALE.IAVAVIGAI...VT.FGG.AAAGG.I.A.KL----....................................................AAKSASKIAQ.KV.TDIATKAAANMAKVAD------...............-M--GSKAATTTA............................................KAIRYGA...........-----------------ET..............................VDLTVNIGKGATDS.....VHAANNANVTEIQADITDLRA.......KMTLSQAVIDKLKEEIGKLMEDFQELMSIIMQMIQA..KSETMQTVLS-r.................................................................................
Q7NUS8_CHRVO/256-580                 ...................LMAMFVELVGKNSEESLKNDLALFQALQEGRQKEMDKKSAEYQEEVRKA..........EELNR...TMG........CIG...KILGALLTVVSV...VAAAFTGGASLAL.AAVGVA-------.......LMVADEVVKAATGVSFMQEAL.....KPLMDKVl...........kpLMDLIGKAITKaLE.GMGVDK...............KTAELAGSIAGAVL.AAVAMVVVM...VV.VAV.VGKGA.-.-.------....................................................AGKLGGALSK.LL.GDAIKKIVPNVLKELAKGGSKM...............LTQGFQRLANSLG............................................LQTDAAA...........-----KQMMANTLGRVVVG..............................GEVAQATSQAGGNV.....AQGVFMKNASDALADFTLARA.......AMEQIEQWLKQAVEVFASTQKVTQELTTAMSAAVQQ..NAEAGRFVLRQ..................................................................................
G2GYS7_9ENTR/309-641                 .............igmfie-------TNNNASVEKLNNNRDRIEKIQLANINELKVKEQEATEAAEKA..........AKLGK...IGT........CIA...KVLTYLIVAVSV...IGAVFTAGASLAI.AAIGIA-------.......LLVTDSVMEAAGVESLSSRMM.....SPLMTEVi...........qpAIKWLTEAFVKiLK.ETGLGDli...........nkAAGKDITEIIATAL.AAVTAIIGM...VV.LMV.VAKVG.G.S.FI----....................................................AKQLGPMFTK.IM.SKIATSAFATAIKNFGQNISKF...............VIKKIPEKLKEWA............................................TQLNEFI...........L---KTLVNGNTIAYTKMS..............................LTVANASVKAGFDI.....NKGVSDKYIYDLRASMMGIEK.......IAEILQELSSEPLKKFMESFDVNNVMTKTLYDSINN..TNKTAQAIL--a.................................................................................
G8Q409_PSEFL/262-588                 ................rlr----IIELLGESAQNKEELSQELFQELQARLQEHMQRESDKYLEEVRKA..........EALQK...TMG........CIG...KIIGAILTVATI...AAGVLTANPVLIAvGVVGAA-------.......VMIADTVIQEKTGKSFMAEAM.....KPLTVVMq............eAIKRFSELYTQlLI.ELGVDE...............DKAKEIGQIAGMIQ.GIVSTLAAV...AL.VAV.VGAQV.I.G.------....................................................--PMVSAVAS.KL.ASVVAQAAP-AAMQAMKQVATS...............VGNTLTQMLTQLR............................................GFITNGA...........-DPVLLARYAANLEIAQAV..............................TEFGNVAVQGGLQI.....KSGQHQAQAAVHLADVRVRMA.......ISEAISAYLTQVVDDYGQAMRERTRQIEQLFADMQR..SHSVSLQM---arh...............................................................................
#=GC seq_cons                        .....................h.h.tlhspsttpphptptp.hpthpptpppphpcphcchpcphpcA..........tcttc...phG........hhu...Klhualhssssl...lsushphusuhsh....slA..............hshss.lhptssstshhttth.....p.h.phh..................................................tpsphhspllsslh.sslshhsuh...hs.sus.hupss.h.t..h........................................................stthspthtp.hh.sphhpphstthscths......................htthtp.stth................................................t......................h.thh..h..h..............................hpsssshspushsh......tuhhptphtph.Acht..ph........hp.hpthhpphhcthtphhpthpphhpth.phhpt..ptph.t.lh..t.................................................................................
//
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