GenomeNet

Database: Pfam
Entry: Stork_head
LinkDB: Stork_head
Original site: Stork_head 
#=GF ID   Stork_head
#=GF AC   PF10264.4
#=GF DE   Winged helix Storkhead-box1 domain
#=GF AU   KOGs, Finn RD, Coggill PC
#=GF SE   KOGs (KOG3897)
#=GF GA   21.20 21.20;
#=GF TC   22.50 21.40;
#=GF NC   21.00 19.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   15806103
#=GF RT   Maternal segregation of the Dutch preeclampsia locus at 10q22
#=GF RT   with a new member of the winged helix gene family. 
#=GF RA   van Dijk M, Mulders J, Poutsma A, Konst AA, Lachmeijer AM,
#=GF RA   Dekker GA, Blankenstein MA, Oudejans CB; 
#=GF RL   Nat Genet. 2005;37:514-519.
#=GF DR   INTERPRO; IPR019391;
#=GF CC   This is the conserved N-terminal winged helix domain of
#=GF CC   Storkhead-box1 protein which is likely to be a DNA binding
#=GF CC   domain. In humans the full-length protein controls
#=GF CC   polyploidization of extravillus trophoblast and is implicated in
#=GF CC   pre-eclampsia.
#=GF SQ   151
#=GS B4PE75_DROYA/118-197  AC B4PE75.1
#=GS F7I1W9_CALJA/111-159  AC F7I1W9.1
#=GS G5EEC5_CAEEL/92-171   AC G5EEC5.1
#=GS E1B8Y9_BOVIN/111-190  AC E1B8Y9.1
#=GS STOX2_MOUSE/63-142    AC Q499E5.2
#=GS E3N5T7_CAERE/92-171   AC E3N5T7.1
#=GS D6WJ40_TRICA/115-173  AC D6WJ40.1
#=GS B4IAJ5_DROSE/118-197  AC B4IAJ5.1
#=GS G3W6K8_SARHA/67-146   AC G3W6K8.1
#=GS E5S453_TRISP/63-142   AC E5S453.1
#=GS H2N281_ORYLA/9-88     AC H2N281.1
#=GS F6XNG8_MONDO/63-142   AC F6XNG8.1
#=GS H9K1E7_APIME/140-219  AC H9K1E7.1
#=GS F1PLZ9_CANFA/94-173   AC F1PLZ9.1
#=GS F1M4Y5_RAT/8-88       AC F1M4Y5.1
#=GS Q4SRX1_TETNG/67-146   AC Q4SRX1.1
#=GS H2NAQ8_PONAB/111-190  AC H2NAQ8.1
#=GS G1N3S3_MELGA/9-88     AC G1N3S3.2
#=GS B3M6U4_DROAN/118-197  AC B3M6U4.1
#=GS Q080Q9_SHEFN/181-245  AC Q080Q9.1
#=GS F6S2T9_HORSE/63-142   AC F6S2T9.1
#=GS F1RSZ9_PIG/7-86       AC F1RSZ9.1
#=GS Q6AWN7_DROME/118-197  AC Q6AWN7.1
#=GS H3CNV2_TETNG/68-147   AC H3CNV2.1
#=GS G7N2B9_MACMU/9-88     AC G7N2B9.1
#=GS H2UUM0_TAKRU/67-146   AC H2UUM0.1
#=GS B8JIT0_DANRE/7-86     AC B8JIT0.1
#=GS G3RDG6_GORGO/11-91    AC G3RDG6.1
#=GS G1LP15_AILME/63-142   AC G1LP15.1
#=GS E0W3J4_PEDHC/21-100   AC E0W3J4.1
#=GS G5CAL1_HETGA/1-80     AC G5CAL1.1
#=GS F6WTW7_XENTR/63-142   AC F6WTW7.1
#=GS F7F7U9_MACMU/9-88     AC F7F7U9.1
#=GS F6SH19_XENTR/117-196  AC F6SH19.1
#=GS G0N6G0_CAEBE/92-171   AC G0N6G0.1
#=GS H2QQH9_PANTR/63-142   AC H2QQH9.1
#=GS G7YCQ9_CLOSI/250-312  AC G7YCQ9.1
#=GS E1BWL1_CHICK/1-80     AC E1BWL1.1
#=GS B1WB79_DANRE/113-192  AC B1WB79.1
#=GS F7CJI1_MACMU/87-166   AC F7CJI1.1
#=GS C3XQE6_BRAFL/147-194  AC C3XQE6.1
#=GS B4N6H8_DROWI/118-197  AC B4N6H8.1
#=GS G1SXS0_RABIT/63-142   AC G1SXS0.1
#=GS E3X0G7_ANODA/211-252  AC E3X0G7.1
#=GS E2CAE4_HARSA/8-87     AC E2CAE4.1
#=GS H2Q1Z9_PANTR/9-88     AC H2Q1Z9.1
#=GS F6Z0Z2_HORSE/14-93    AC F6Z0Z2.1
#=GS E5T4C3_TRISP/18-97    AC E5T4C3.1
#=GS H0Y8U0_HUMAN/8-69     AC H0Y8U0.1
#=GS E9GA00_DAPPU/72-151   AC E9GA00.1
#=GS STOX2_HUMAN/63-142    AC Q9P2F5.2
#=GS Q0IFJ2_AEDAE/74-153   AC Q0IFJ2.1
#=GS E4WZD8_OIKDI/112-191  AC E4WZD8.1
#=GS F6QZ35_MOUSE/19-98    AC F6QZ35.1
#=GS H9GFS6_ANOCA/116-195  AC H9GFS6.1
#=GS G3H6U3_CRIGR/1-80     AC G3H6U3.1
#=GS Q7Q578_ANOGA/118-197  AC Q7Q578.4
#=GS G3UGT8_LOXAF/14-93    AC G3UGT8.1
#=GS G1MI28_AILME/14-93    AC G1MI28.1
#=GS G3R3M3_GORGO/25-104   AC G3R3M3.1
#=GS F1NUU5_CHICK/84-163   AC F1NUU5.1
#=GS B0X275_CULQU/10-89    AC B0X275.1
#=GS F1PZE7_CANFA/88-167   AC F1PZE7.1
#=GS G3RM31_GORGO/111-190  AC G3RM31.1
#=GS H0VTQ3_CAVPO/111-190  AC H0VTQ3.1
#=GS F1SUH0_PIG/111-190    AC F1SUH0.1
#=GS G7PDC3_MACFA/9-88     AC G7PDC3.1
#=GS H0WQP9_OTOGA/63-142   AC H0WQP9.1
#=GS Q9VP79_DROME/118-197  AC Q9VP79.1
#=GS D3ZD45_RAT/11-90      AC D3ZD45.1
#=GS G7P6M3_MACFA/63-142   AC G7P6M3.1
#=GS G9KRQ1_MUSPF/7-86     AC G9KRQ1.1
#=GS G5B801_HETGA/14-93    AC G5B801.1
#=GS H3B916_LATCH/12-91    AC H3B916.1
#=GS F6ZIR6_XENTR/120-199  AC F6ZIR6.1
#=GS H0XWH6_OTOGA/111-190  AC H0XWH6.1
#=GS A8PYW3_BRUMA/99-173   AC A8PYW3.1
#=GS H2UUL9_TAKRU/68-147   AC H2UUL9.1
#=GS G3T8S5_LOXAF/68-147   AC G3T8S5.1
#=GS H0VGZ6_CAVPO/11-90    AC H0VGZ6.1
#=GS D2GXI6_AILME/9-88     AC D2GXI6.1
#=GS Q6AZN5_XENLA/1-80     AC Q6AZN5.1
#=GS H9I7E8_ATTCE/23-102   AC H9I7E8.1
#=GS A3KNW9_DANRE/113-192  AC A3KNW9.1
#=GS H2UA27_TAKRU/8-87     AC H2UA27.1
#=GS F1MYB0_BOVIN/7-85     AC F1MYB0.2
#=GS F1SUG9_PIG/111-190    AC F1SUG9.1
#=GS F7I1W1_CALJA/111-190  AC F7I1W1.1
#=GS F8W5K8_DANRE/67-146   AC F8W5K8.1
#=GS D4A001_RAT/63-142     AC D4A001.1
#=GS B4KWK6_DROMO/118-197  AC B4KWK6.1
#=GS O18363_DROME/118-197  AC O18363.1
#=GS G7YS51_CLOSI/26-107   AC G7YS51.1
#=GS A4IGX1_XENTR/120-199  AC A4IGX1.1
#=GS STOX2_MACFA/63-142    AC Q95K63.1
#=GS G1KBE6_ANOCA/12-91    AC G1KBE6.1
#=GS G3Q7N1_GASAC/9-88     AC G3Q7N1.1
#=GS H3CJY1_TETNG/20-99    AC H3CJY1.1
#=GS H9FXE0_MACMU/63-142   AC H9FXE0.1
#=GS Q4SXR1_TETNG/11-90    AC Q4SXR1.1
#=GS H2RPC0_TAKRU/8-87     AC H2RPC0.1
#=GS STOX1_HUMAN/111-190   AC Q6ZVD7.2
#=GS H9JT30_BOMMO/1-55     AC H9JT30.1
#=GS B4IYW7_DROGR/118-197  AC B4IYW7.1
#=GS Q4SKZ3_TETNG/9-88     AC Q4SKZ3.1
#=GS Q29E39_DROPS/119-198  AC Q29E39.2
#=GS G1RLU2_NOMLE/106-185  AC G1RLU2.1
#=GS G7MSD6_MACMU/39-118   AC G7MSD6.1
#=GS A8XI35_CAEBR/47-126   AC A8XI35.2
#=GS B7PDA2_IXOSC/32-111   AC B7PDA2.1
#=GS G3NYR7_GASAC/115-194  AC G3NYR7.1
#=GS E1FW34_LOALO/99-178   AC E1FW34.1
#=GS H0Z8C8_TAEGU/63-142   AC H0Z8C8.1
#=GS H2RPB9_TAKRU/11-90    AC H2RPB9.1
#=GS H2ZYV2_LATCH/63-142   AC H2ZYV2.1
#=GS F1QH77_DANRE/9-88     AC F1QH77.1
#=GS G1QBA1_MYOLU/11-90    AC G1QBA1.1
#=GS F7HNI1_CALJA/63-142   AC F7HNI1.1
#=GS H2LT58_ORYLA/8-87     AC H2LT58.1
#=GS H1A0Y3_TAEGU/9-88     AC H1A0Y3.1
#=GS H9H6F0_MONDO/10-89    AC H9H6F0.1
#=GS G4VQK5_SCHMA/14-94    AC G4VQK5.1
#=GS G3W6K9_SARHA/73-152   AC G3W6K9.1
#=GS F6W3H4_ORNAN/1-36     AC F6W3H4.1
#=GS G3VVL3_SARHA/35-114   AC G3VVL3.1
#=GS G1Q775_MYOLU/40-119   AC G1Q775.1
#=GS G1SII2_RABIT/113-192  AC G1SII2.1
#=GS B2RQL2_MOUSE/108-187  AC B2RQL2.1
#=GS H0Z029_TAEGU/9-88     AC H0Z029.1
#=GS G6CTC3_DANPL/136-215  AC G6CTC3.1
#=GS G1MYI9_MELGA/10-89    AC G1MYI9.1
#=GS G3PXR5_GASAC/9-88     AC G3PXR5.1
#=GS G1RIS6_NOMLE/63-142   AC G1RIS6.1
#=GS G1PX76_MYOLU/14-93    AC G1PX76.1
#=GS H2PEU4_PONAB/87-166   AC H2PEU4.1
#=GS B4QJM6_DROSI/118-197  AC B4QJM6.1
#=GS Q5R479_PONAB/63-142   AC Q5R479.1
#=GS B3NIV5_DROER/243-322  AC B3NIV5.1
#=GS H2LVD2_ORYLA/92-171   AC H2LVD2.1
#=GS F1QWT9_DANRE/116-195  AC F1QWT9.2
#=GS E9IZ76_SOLIN/161-240  AC E9IZ76.1
#=GS Q675T4_OIKDI/112-191  AC Q675T4.1
#=GS C9JRL1_HUMAN/1-80     AC C9JRL1.1
#=GS F1R106_DANRE/8-87     AC F1R106.1
#=GS B4H3Z5_DROPE/42-119   AC B4H3Z5.1
#=GS D2GY60_AILME/86-165   AC D2GY60.1
#=GS B4F6Q2_DANRE/113-192  AC B4F6Q2.1
#=GS E3X0G6_ANODA/1-35     AC E3X0G6.1
#=GS H2VS24_CAEJA/92-171   AC H2VS24.1
#=GS D6RDA5_HUMAN/1-80     AC D6RDA5.1
#=GS B4LEC3_DROVI/118-197  AC B4LEC3.1
B4PE75_DROYA/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRGKLGARFP.H..MT..TPATEVIYDSLAQLMQEQKIYQTSKGYFIFTPE................
F7I1W9_CALJA/111-159             ........MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLEHLMKHYP.G..--..---------------------------------hrvw............
G5EEC5_CAEEL/92-171              .......i-QQVEQMHFVPLGDVICDAVAQLNRQGLAATEQAIRQYVARHCP.H..VA..PPGIEMVRQTITSLLSTGFVYKMADHYFVSVP-t...............
E1B8Y9_BOVIN/111-190             ........MNPIAQSQFIPLAEVLCCAISDMNADQIVVTQESLLEHLMKRYP.G..IA..IPSRDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
STOX2_MOUSE/63-142               ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
E3N5T7_CAERE/92-171              .......i-QQVEQMHFVPLGDVICDAVAQLNRNGMTASEQAIRQYVARHCP.H..VA..PPGIEMVRQTIASLLATGFVYKMAEHYFVSVP-t...............
D6WJ40_TRICA/115-173             .......g-SPVAQTQWTPLPEAVCAVILRLSRQGRPAGIETIREALIMAFP.H..DK..I--------------------------------ineilinlqcl.....
B4IAJ5_DROSE/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRSKLGSRFP.H..MT..TPATEVIYDSLAQLMQEQKIYQTSKGYFIFTPE................
G3W6K8_SARHA/67-146              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTPEALMEHLTTCFP.G..VP..TPSQEILRHTLSMLVRERKIYPTPDGYFIVTPQ................
E5S453_TRISP/63-142              ........MHEVPQTQFIPLSDVLCTVISALNRIGQPATIQSIMEALRQQYV.G..MT..IPKEDMIYAAIGGLMAQGRLYCMGNHYFISTP-f...............
H2N281_ORYLA/9-88                ........MSPISQPQFIPLGEVLLLAISALNSAHKPVTEEALTEHLQTCFQ.G..VP..TPTEEALHHTLSMLVHERKIYPTPNGYFIVTPQ................
F6XNG8_MONDO/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTPEALMEHLTTCFP.G..VP..TPSQEILRHTLNMLVRERKIYPTPDGYFIVTPQ................
H9K1E7_APIME/140-219             ........VAPVAQGQFTPLPEALCWAILELTSQRQAATLDTLRSALRNAFP.A..MQ..RPSRELVYDALAKLMQERKIYHTSQGYFVVTPE................
F1PLZ9_CANFA/94-173              ........MNPIAQSQFIPLAEVLCCAVSDMNAAQIVVTQESLLEHLMKHYP.G..IA..IPSQDVLYTTLGTLIKERKIYHTGEGYFIVTPQ................
F1M4Y5_RAT/8-88                  ........MSLIAQRRFVPLAEVLCCVIADMNAGQVAVTQEALLEHLMKHYPvG..IA..VPSPDILYSTLGTLIQQRKIYHTGEGYFIVTPN................
Q4SRX1_TETNG/67-146              ........MSPISQSQFIPLGEILCLAISAMNSAHKPVNQEALVEHLTASFP.G..VP..TPSSEVLRHTLNMLVRERKIYPTPEGYFIVTPQ................
H2NAQ8_PONAB/111-190             ........MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYP.G..IA..IPSEDILYTTLGMLIKERKIYHTGEGYFIVTPQ................
G1N3S3_MELGA/9-88                ........MSPISQSQFIPLGEILCLAISAMNSARKQVTQEALMEHLTTCFP.G..VP..TPSPEILRHTLNMLVRERKIYPTPDGYFIVTPQ................
B3M6U4_DROAN/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRGKLGTRFP.H..MT..TPATEVIYDTLAQLMQEQKIYQTSKGYFIFTPE................
Q080Q9_SHEFN/181-245             ...devaf------LQLTPLSAQVLAYIEQMTHSQQGVTVDAIISWLSEHYP.Q..M-..-PNDTLLSGCLP---------------------llqqlaqkg.......
F6S2T9_HORSE/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
F1RSZ9_PIG/7-86                  ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
Q6AWN7_DROME/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRSKLGSRFP.H..MT..TPATEVIYDSLAQLMQEQKIYQTSKGYFIFTPE................
H3CNV2_TETNG/68-147              ........MSPISQSQFIPLGEILCLAISAMNSAHKPVNQEALVEHLTASFP.G..VP..TPSSEVLRHTLNMLVRERKIYPTPEGYFIVTPQ................
G7N2B9_MACMU/9-88                ........MNPITQSQFVPLGEVLCCAISDMNTAQIGVTQESLLEHLMKHYP.G..IA..IPSEDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
H2UUM0_TAKRU/67-146              ........MSPISQSQFIPLGEILCLAISAMNSAHKPVNQEALVEHLTASFP.G..VP..TPSSEVLRHTLNMLVRERKIYPTPEGYFIVTPQ................
B8JIT0_DANRE/7-86                ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQDALMEHLATCFP.G..VP..TPSPEILRHTLNMLVRERKIYPTPEGYFIVTPQ................
G3RDG6_GORGO/11-91               ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPaG..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
G1LP15_AILME/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
E0W3J4_PEDHC/21-100              .......v-SLINQGQFTPLPEALCWVILELTSSGQHAVLESIRNCLHLSFP.D..IE..KPSSQVVYDTLAKLMSDKKIYQTSQGYFIITPE................
G5CAL1_HETGA/1-80                ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
F6WTW7_XENTR/63-142              ........MSPISQSQFIPLGEILCVAISAMNSARKPVTQEALIEHLTTFFP.G..VP..TPSPEVLRHTLNMLVRERKIYPTPDGYYIVTPQ................
F7F7U9_MACMU/9-88                ........MNPITQSQFVPLGEVLCCAISDMNTAQIGVTQESLLEHLMKHYP.G..IA..IPSEDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
F6SH19_XENTR/117-196             ........MNPISQSHFIPLAEVLCCAISDMNTTQILVTQESLLEHLNKHYR.G..IA..TPSQDILYNALGTLIRERKIYHTGEGYFIVTPQ................
G0N6G0_CAEBE/92-171              .......i-QQVEQMHFVPLGDVICDAVSQLNRGGVPASEQAIRQYVARHCP.H..VA..PPGIEMVRQTINSLLATGYVYKMGDHYFVSVP-t...............
H2QQH9_PANTR/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
G7YCQ9_CLOSI/250-312             iapnnlpg-------------------------DGGKVNLEKIYNCLNSWYS.G..LC..LPSRESIQQALDELIASGQVYCTDYGYNVMT--id..............
E1BWL1_CHICK/1-80                ........MNPCSLPQSIPLAEGICRTISDMNADQMMVTQKTLVEQLVKRYP.G..IA..VPSQKILYNILGTLIKERKIYHTGEGYFIVTPN................
B1WB79_DANRE/113-192             ........MSPISQSQFIPLSEILCSVISDLNADHVVVNQEALINYMMKSHP.G..MT..IPTQDILYNALGTLIKERKIYHTGEGYFVVTPQ................
F7CJI1_MACMU/87-166              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
C3XQE6_BRAFL/147-194             .......l-APVSQSHFIPLPDVLCQTIAELNCGKGIATQA-----------.-..--..---------------------------------gkvetdrmqrlgrmt.
B4N6H8_DROWI/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTSEGQSATIEHVRGKLGVRFP.H..MT..TPATEVIYDTLAQLMQEQKIYQTSKGYFIFTPE................
G1SXS0_RABIT/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKVYPTPEGYFIVTPQ................
E3X0G7_ANODA/211-252             ........VTPIVQTQFTPLTEALCDVIMELTSQGQSATIENIRNRLRS---.-..--..---------------------------------r...............
E2CAE4_HARSA/8-87                ........VAPVSQGQFTPLPEALCWAILELTSQRQAATLDTLRSALRNAFP.A..MQ..RPSRELVYDALAKLMQERKIYHTSQGYFVVTPE................
H2Q1Z9_PANTR/9-88                ........MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYP.G..IA..IPSEDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
F6Z0Z2_HORSE/14-93               ........MNPVAQSQFVPLAEVLCCVISDMNAAQIVVTQESLVEHLMKHYP.G..IA..VPSQDILHTTLGILIKERKIYHTGEGYFIVTP-h...............
E5T4C3_TRISP/18-97               ........MHEVPQTQFIPLSDVLCTVISALNRIGQPATIQSIMEALRQQYV.G..MT..IPKEDMIYAAIGGLMAQGRLYCMGNHYFISTP-f...............
H0Y8U0_HUMAN/8-69                ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.V..L-..---------------------------------grawlpthqallkvtv
E9GA00_DAPPU/72-151              ........VQPISQSQFTPLPEALCWVIWELNLAERSTALDDVTAALGNAFP.D..LV..PPSNKVVYDTLGKLIRDRKIFYNGKGYGVVTP-d...............
STOX2_HUMAN/63-142               ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
Q0IFJ2_AEDAE/74-153              ........VTPIVQTQFTPLTEALCDVIMELTTQGQSATIENIRSRLRTRFT.H..MQ..QPSVEVIYDTLVQLMQEIKIYQTSKGYFIVTPE................
E4WZD8_OIKDI/112-191             ........MESIPQKTRIELPDLVLMAVADLNHQTFPAHAATIQQHLTEKCD.E..MI..IPSTASIEYCLTNLLKAKKIYTHSGGFRIVVHK................
F6QZ35_MOUSE/19-98               ........MSPIAQCRFVPLAEVLCCAIADMNAAQVMVTQQSLLEHLIKHYP.G..IA..VPSPDILYSTLGALIQERKIYHTGEGYFIVTP-s...............
H9GFS6_ANOCA/116-195             ........MNPISQSQFVPLEEVLCCAISDMNAAHITVTQDTLLDQLGKHYP.G..IA..APTHDILYSTLGMLIKERKIYHTGEGYFIVTPN................
G3H6U3_CRIGR/1-80                ........MSPIAQCQFVPLAEVLCCTIADMNAGQVAVTQESLLEHLVKLYP.G..IA..VPSPDILYSTLGALIQERKIYHTGEGYFIVTPN................
Q7Q578_ANOGA/118-197             ........VTPIVQTQFTPLTEALCDVIMELTSQGQSATIENIRNRLRSRFT.H..MQ..QPSVEVIYDTLVQLMQEIKIYQTSKGYFIVTPE................
G3UGT8_LOXAF/14-93               ........MNLIAQSQFLPLAEVLCCAVSDLNAAQVVVTQESLREHLLRQYP.G..IA..VPSQDILYATLGTLIKERKIYHTGEGYFIVTPQ................
G1MI28_AILME/14-93               ........MNPIAQSQFIPLAEVLCCAVSDMNAAQTVVTQETLLEHLMKHHP.G..IA..IPSQDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
G3R3M3_GORGO/25-104              ........MNPINQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYP.G..IA..IPSEDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
F1NUU5_CHICK/84-163              ........MSPISQSQFIPLGEILCLAISAMNSARKQVTQEALMEHLTTCFP.G..VP..TPSPEILRHTLNMLVRERKIYPTPDGYFIVTPQ................
B0X275_CULQU/10-89               ........VTPIVQTQFTPLTEALCDVIMELTSQGQSATVEHIRTRLRSRFT.H..MQ..QPSVEVIYDTLVQLMQEIKIYQTSKGYFIVTPE................
F1PZE7_CANFA/88-167              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
G3RM31_GORGO/111-190             ........MNPINQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYP.G..IA..IPSEDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
H0VTQ3_CAVPO/111-190             ........MNPIAQSQFVPLAEVLCCAISDMNTAQIVVTQESLLEHLKEHYP.G..IA..LPSQDILYTTLGTLIKERKIYHTGEGYFIVTSQ................
F1SUH0_PIG/111-190               ........MNPIAQSQFIPLAEVLCCAVSDMNAAQIVATQGSLLEYLMKHYP.G..IA..IPSQDTLYTTLGTLIKERKIYHTGEGYFIVTPQ................
G7PDC3_MACFA/9-88                ........MNPITQSQFVPLGEVLCCAISDMNTAQIGVTQESLLEHLMKHYP.G..IA..IPSEDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
H0WQP9_OTOGA/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
Q9VP79_DROME/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRSKLGSRFP.H..MT..TPATEVIYDSLAQLMQEQKIYQTSKGYFIFTPE................
D3ZD45_RAT/11-90                 ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
G7P6M3_MACFA/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
G9KRQ1_MUSPF/7-86                ........MNPIAQSQFVPLAEVLCCAVSDLNAAQTVVTQESLLEHLKQHYP.G..IA..IPSQDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
G5B801_HETGA/14-93               ........MNPIAQSQFVSLAEVLCCAISDMNTAQIVVTQETLLEHLKRHYP.G..IA..LPPQDTLYTALGTLIKERKIYHTGEGYFIVTPQ................
H3B916_LATCH/12-91               ........MTPITQSQFIPLAEVLCSAISDMNAAHTVVTQETLMDHLVKYYP.G..IA..TPTQEILYNALGALIKERKIYHTGEGYFIVTPQ................
F6ZIR6_XENTR/120-199             ........MSPISQSQFIPLGEILCVAISAMNSARKPVTQEALIEHLTTFFP.G..VP..TPSPEVLRHTLNMLVRERKIYPTPDGYYIVTPQ................
H0XWH6_OTOGA/111-190             ........MNPIAQSQFVPLADILCCAISDMNVAQTVVTQESLLEHLMKHYP.G..IA..IPSQDILYATLGTLIRERKIYHTGEGYFIVTPR................
A8PYW3_BRUMA/99-173              ........MHKIDQMHLVPLLDIICNVVFKMNQSGRPAFLDVLLDEIRKEYP.K..IE..PPSAKTFRQAIHTLLKQ----------------nileydleqly.....
H2UUL9_TAKRU/68-147              ........MSPISQSQFIPLGEILCLAISAMNSAHKPVNQEALVEHLTASFP.G..VP..TPSSEVLRHTLNMLVRERKIYPTPEGYFIVTPQ................
G3T8S5_LOXAF/68-147              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
H0VGZ6_CAVPO/11-90               ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
D2GXI6_AILME/9-88                ........MNPIAQSQFIPLAEVLCCAVSDMNAAQTVVTQETLLEHLMKHHP.G..IA..IPSQDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
Q6AZN5_XENLA/1-80                ........MSPISQSQFIPLGEILCVAIAALNSARKPVNQEALIDHLTTFFP.G..VP..TPSPEVLRHTLNMLVRERKIYPTPDGYYIVTPQ................
H9I7E8_ATTCE/23-102              ........VAPVSQGQFTPLPEALCWAILELTSQRQAATLDTLRSALRNAFP.A..MQ..RPSRELVYDALAKLMQERKIYHTSQGYFVVTPE................
A3KNW9_DANRE/113-192             ........MSPISQSQFIPLSEILCSVISDLNADHVVVNQEALINYMMKSHP.G..MT..IPTQDILYNALGTLIKERKIYHTGEGYFVVIPQ................
H2UA27_TAKRU/8-87                ........MSPVPQSQFIPLAEVLCSVISDMNAADITVSQEALVSYMSKAHP.G..IT..IPSQDILYNALGTLIKERKIYHTGEGYFIVTPQ................
F1MYB0_BOVIN/7-85                ........MSPISQSQFIPLEEI-CLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
F1SUG9_PIG/111-190               ........MNPIAQSQFIPLAEVLCCAVSDMNAAQIVATQGSLLEYLMKHYP.G..IA..IPSQDTLYTTLGTLIKERKIYHTGEGYFIVTPQ................
F7I1W1_CALJA/111-190             ........MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLEHLMKHYP.G..IA..IPSQDTLYTTLGMLIKERKIYHTGEGYFIVTPQ................
F8W5K8_DANRE/67-146              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQDALMEHLATCFP.G..VP..TPSPEILRHTLNMLVRERKIYPTPEGYFIVTPQ................
D4A001_RAT/63-142                ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
B4KWK6_DROMO/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRSKLGVRFP.H..MT..TPATEVIYDSLAQLMQEQKIYQTAKGYFIFTPE................
O18363_DROME/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRSKLGSRFP.H..MT..TPATEVIYDSLAQLMQEQKIYQTSKGYFIFTPE................
G7YS51_CLOSI/26-107              ........MQRVPQYRTMRLEEVICQLIWQHTQTEASCSMEQLMSALTKVYR.DlqMR..RPSYEAVKVALSALLSAGAVYFSGRGYSLLT--ad..............
A4IGX1_XENTR/120-199             ........MSPISQSQFIPLGEILCVAISAMNSARKPVTQEALIEHLTTFFP.G..VP..TPSPEVLRHTLNMLVRERKIYPTPDGYYIVTPQ................
STOX2_MACFA/63-142               ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
G1KBE6_ANOCA/12-91               ........MSPISQSQFIPLGEILCLAISAMNSARKQVTQEALMEHLTTCFP.G..VP..TPSPEILRHTLNMLVRERKIYPTPDGYFIVTPQ................
G3Q7N1_GASAC/9-88                ........MSPISQSQFIPLGEVLLLAISAMNSAHKPVTQEALTEHLQTCFP.G..VP..TPTEEVLHHTLSMLVRERKIYPKPDGYFIVTPQ................
H3CJY1_TETNG/20-99               ........MSPISQSQFIPLGEVLLLAISAMNSAHKSVTQETLTEHLQTCFP.G..VP..TPSEEVLHHTLSMLVHERKICPTPNGYLNITPQ................
H9FXE0_MACMU/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
Q4SXR1_TETNG/11-90               ........MSPISQSQFIPLGEVLLLAISAMNSAHKSVTQETLTEHLQTCFP.G..VP..TPSEEVLHHTLSMLVHERKICPTPNGYLNITPQ................
H2RPC0_TAKRU/8-87                ........MSPISQSQFIPLGEVLLLAISAMNSAHKSVTQETLTEHLQTCFP.G..VP..TPSEEVLHHTLSMLVHERKICPTPNGYFNITPQ................
STOX1_HUMAN/111-190              ........MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYP.G..IA..IPSEDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
H9JT30_BOMMO/1-55                ........-------------------------QGQAATLESIRTSLLSKFP.S..MQ..TPSQEVVYDTLAQLMQERKIYQTSRGFFIVTPE................
B4IYW7_DROGR/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRCKLGIRFP.H..MT..TPATEVIYDTLAQLMQEQKIYQTAKGYFIFTPE................
Q4SKZ3_TETNG/9-88                ........MSPVAQSQFIPLAEVLCSVISDMNAAEITVSQEALVSYMSKAHP.G..IT..IPSQDILYNALGALIKERKVYHTGEGYFIVTPQ................
Q29E39_DROPS/119-198             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATVEHVRGKLGARFP.H..MT..TPATEVIYDTLAQLMQEQKIYQTSKGYFIFTPE................
G1RLU2_NOMLE/106-185             ........MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLEHLMKHYP.G..IA..IPSEDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
G7MSD6_MACMU/39-118              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
A8XI35_CAEBR/47-126              .......i-QQVEQMHFVPLGDVICDAVAQLNRGGLAATEQSIRQHVARHCP.H..VA..PPGIEMVRQTIASLLATGFVYKMADHYFVSVP-t...............
B7PDA2_IXOSC/32-111              ........MVQVLQTQFAPLAEALCKAVFDLTSRGDTATLDTISAQLTAAFP.A..IE..RPGSDVVYRALGALIRERRLYHTGVGYQRII--gq..............
G3NYR7_GASAC/115-194             ........MSPVPQSQFIPLAEVLCSVISDMNSSQITVNQEALINYMSKAHS.G..IT..IPTQDILYNALGNLIKERKIYHTGEGYFIVTPQ................
E1FW34_LOALO/99-178              ........MHKIDQMHLVPLMDIICNVVFKMNQSGRPAVFEALLDEIREGYP.K..IE..PPSTRTLRQAIQTLLKQE---------------ileyhleqlyicfph.
H0Z8C8_TAEGU/63-142              ........MSPITQSQFIPLGEILCLAISAMNSARKQVTQEALMEHLTTCFP.G..VP..TPSPEILRHTLNMLVRERKIYPTPDGYFIVTPQ................
H2RPB9_TAKRU/11-90               ........MSPISQSQFIPLGEVLLLAISAMNSAHKSVTQETLTEHLQTCFP.G..VP..TPSEEVLHHTLSMLVHERKICPTPNGYFNITPQ................
H2ZYV2_LATCH/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLATCFP.G..VP..TPSPEILRHTLNMLVRERKIYPTPDGYFIVTPQ................
F1QH77_DANRE/9-88                ........MSPISQSQFIPLGEILCLAISAMNSARKTVTQETLIEHLATCFP.G..VP..TPSMEILRHTLNMLVRERKIYPTPEGYFIVTQQ................
G1QBA1_MYOLU/11-90               ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPEGYFIVTPQ................
F7HNI1_CALJA/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
H2LT58_ORYLA/8-87                ........MSPVPQSQFIPLAEVLCSVISDMNTAQITVSQEALVNHMSKVHP.G..IT..IPTQDILYNALGTLIKERKIYHTGEGYFIVTPQ................
H1A0Y3_TAEGU/9-88                ........MSPITQSQFIPLGEILCLAISAMNSARKQVTQEALMEHLTTCFP.G..VP..TPSPEILRHTLNMLVRERKIYPTPDGYFIVTPQ................
H9H6F0_MONDO/10-89               ........MNPITQSQFIPLAEVLCCAIADMNAAHVVVTQESLLDQLVKHYP.G..IA..TPSQEVLYSTLGSLIKERKIYHTGEGYFIVTPQ................
G4VQK5_SCHMA/14-94               .....let----SQFNAMRLEEVICQLVWQVTQSEPSCSVERLVKYLEDVYR.S..IQlpIPSLEDVNNSLAVLTRAGAIYFSGHGYNLLTPE................
G3W6K9_SARHA/73-152              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTPEALMEHLTTCFP.G..VP..TPSQEILRHTLSMLVRERKIYPTPDGYFIVTPQ................
F6W3H4_ORNAN/1-36                ........--------------------------------------------.G..LA..TPSPDILYTTLGTLIKERKIYHTGEGYFVVTPQ................
G3VVL3_SARHA/35-114              ........MNPITQSQFIPLAEVLCCAIADMNAAHVVVTQESLMDQLVKHYP.G..IA..TPSQDILYTTLGNLIKERKIYHTGEGYFIVTPQ................
G1Q775_MYOLU/40-119              ........MNPIAQSQFIPLAEALCCAISDMNAAEIVVTQESLLEHLMKHYP.G..IA..IPSRDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
G1SII2_RABIT/113-192             ........MNPIAQSQFVPLAEVVCCAVSDMNAAQTVVTQESLLDHLMKHYP.G..IA..IPSQDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
B2RQL2_MOUSE/108-187             ........MSPIAQCRFVPLAEVLCCAIADMNAAQVMVTQQSLLEHLIKHYP.G..IA..VPSPDILYSTLGALIQERKIYHTGEGYFIVTP-s...............
H0Z029_TAEGU/9-88                ........MNPLLQPCSVPLAEGIYWTISDMNADHVMVTQETLLEQLVKNYP.G..IA..VPSHKVLHNILGTLIMERKIYHTGEGYFTVTP-n...............
G6CTC3_DANPL/136-215             ........VTPTYQGQFTPLPEALCDCIMDLTTQGQSATLESIRTSLSSKFP.S..MQ..TPSQEVVYDTLAQLMQERKIYQTSRGFFIVTPE................
G1MYI9_MELGA/10-89               ........MNPCSLSQSIPLAEGICCAISDMNAHQRMVTQKTLVEQLVKRYP.G..IA..VPSQKILYNILGTLIKERKIYHTGEGYFIVTPN................
G3PXR5_GASAC/9-88                ........MSPISQSQFIPLGEILCLAISAMNSAHKPVNQEALVEHLTATFP.G..VP..TPSSEVLRHTLNMLVRERKIYPTPEGYFIVTPQ................
G1RIS6_NOMLE/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
G1PX76_MYOLU/14-93               ........MNPIAQSQFIPLAEALCCAISDMNAAEIVVTQESLLEHLMKHYP.G..IA..IPSRDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
H2PEU4_PONAB/87-166              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
B4QJM6_DROSI/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRSKLGSRFP.H..MT..TPATEVIYDSLAQLMQEQKIYQTSKGYFIFTPE................
Q5R479_PONAB/63-142              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
B3NIV5_DROER/243-322             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRGKLGARFP.H..MT..TPATEVIYDSLAQLMQEQKIYQTSKGYFIFTPE................
H2LVD2_ORYLA/92-171              ........MSPISQSQFIPLGEILCLAISAMNAAHKPVNQEALVEHLTASFP.G..VP..TPSSEVLRHTLNMLVRERKIYPTPEGYFIVTPQ................
F1QWT9_DANRE/116-195             ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQDALMEHLATCFP.G..VP..TPSPEILRHTLNMLVRERKIYPTPEGYFIVTPQ................
E9IZ76_SOLIN/161-240             ........VAPVSQGQFTPLPEALCWAILELTSQRQAATLDTLRSALRNAFP.A..MQ..RPSRELVYDALAKLMQERKIYHTSQGYFVVTPE................
Q675T4_OIKDI/112-191             ........MESIPQKTRIELPDLVLMAVADLNHQTFPAHAATIQQHLTEKCD.E..MI..IPSTASIEYCLTNLLKAKKIYTHSGGFRIVVHK................
C9JRL1_HUMAN/1-80                ........MNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYP.G..IA..IPSEDILYTTLGTLIKERKIYHTGEGYFIVTPQ................
F1R106_DANRE/8-87                ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQDALMEHLATCFP.G..VP..TPSPEILRHTLNMLVRERKIYPTPEGYFIVTPQ................
B4H3Z5_DROPE/42-119              ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATVEHVRGKLGARFP.H..MT..TPATEVIYDTLAQLMQEQKIYQTSKGI------lhly............
D2GY60_AILME/86-165              ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
B4F6Q2_DANRE/113-192             ........MSPISQSQFIPLSEILCSVISDLNADHVVVNQEALINYMMKSHP.G..MT..IPTQDILYNALGTLIKERKIYHTGEGYFVVTPQ................
E3X0G6_ANODA/1-35                ........--------------------------------------------.-..MQ..QPSVEVIYDTLVQLMQEIKIYQTSKGYFIVTPE................
H2VS24_CAEJA/92-171              .......i-QQVEQMHFVPLGDVICDAVAQLNRNGSPASEQAIRQYVARHCP.H..VA..PPGIEMVRQTITSLLATGFVHKMGEHYFVSVP-t...............
D6RDA5_HUMAN/1-80                ........MSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFP.G..VP..TPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQ................
B4LEC3_DROVI/118-197             ........VTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRSKLGVRFP.H..MT..TPATEVIYDSLAQLMQEQKIYQTAKGYFIFTPE................
#=GC seq_cons                    ........MoPIuQSQFlPLuElLChAISsMNuAppsVTQEuLhE+LsppaP.G..ls..sPSpElLhpTLspLl+ERKIY.Ts-GYFIVTPQ................
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