GenomeNet

Database: Pfam
Entry: TBD
LinkDB: TBD
Original site: TBD 
#=GF ID   TBD
#=GF AC   PF12845.2
#=GF DE   TBD domain
#=GF AU   Bateman A, Masci AM
#=GF SE   [1]
#=GF GA   21.40 21.40;
#=GF TC   21.70 22.40;
#=GF NC   20.70 21.20;
#=GF BM   hmmbuild --amino HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   17568778
#=GF RT   SINTBAD, a novel component of innate antiviral immunity, shares
#=GF RT   a TBK1-binding domain with NAP1 and TANK.
#=GF RA   Ryzhakov G, Randow F;
#=GF RL   EMBO J. 2007;26:3180-3190.
#=GF DR   INTERPRO; IPR024581;
#=GF CC   The Tbk1/Ikki binding domain (TBD) is a 40 amino acid domain
#=GF CC   able to bind kinases, has been found to be essential for
#=GF CC   poly(I:C)-induced IRF activation [1]. The domain is found in
#=GF CC   SINTBAD, TANK and NAP1 protein. This domain is predicted to form
#=GF CC   an a-helix with residues essential for kinase binding clustering
#=GF CC   on one side [1].
#=GF SQ   157
#=GS TANK_HUMAN/130-186      AC Q92844.2
#=GS TANK_HUMAN/130-186      DR PDB; 1KZZ B; 1-10;
#=GS TANK_HUMAN/130-186      DR PDB; 1L0A B; 1-9;
#=GS H2TA08_TAKRU/260-310    AC H2TA08.1
#=GS F7E486_HORSE/212-266    AC F7E486.1
#=GS H7C3L4_HUMAN/21-77      AC H7C3L4.1
#=GS F6SY96_MOUSE/1-53       AC F6SY96.1
#=GS A1L1J0_RAT/128-184      AC A1L1J0.1
#=GS G7PU58_MACFA/284-337    AC G7PU58.1
#=GS B2R7S3_HUMAN/130-186    AC B2R7S3.1
#=GS F6ZGJ1_ORNAN/227-278    AC F6ZGJ1.1
#=GS G1QMY3_NOMLE/130-186    AC G1QMY3.1
#=GS D3DTT5_HUMAN/286-341    AC D3DTT5.1
#=GS G3NQ65_GASAC/108-163    AC G3NQ65.1
#=GS D3Z7S3_MOUSE/77-131     AC D3Z7S3.1
#=GS F7FH52_MONDO/227-286    AC F7FH52.1
#=GS H2M9R1_ORYLA/265-323    AC H2M9R1.1
#=GS F7DUU2_XENTR/275-330    AC F7DUU2.1
#=GS H3BCD3_LATCH/213-269    AC H3BCD3.1
#=GS F7AZG4_ORNAN/148-205    AC F7AZG4.1
#=GS F7BNJ6_HORSE/130-155    AC F7BNJ6.1
#=GS B7ZS21_XENLA/190-249    AC B7ZS21.1
#=GS G1T830_RABIT/286-332    AC G1T830.1
#=GS F7DLM0_MONDO/149-205    AC F7DLM0.1
#=GS Q3UGW0_MOUSE/129-185    AC Q3UGW0.1
#=GS G1KPN5_ANOCA/230-286    AC G1KPN5.1
#=GS G3QIP7_GORGO/145-201    AC G3QIP7.1
#=GS G1T8F3_RABIT/212-266    AC G1T8F3.1
#=GS AZI2_RAT/224-277        AC Q4KMA0.1
#=GS H2PBA7_PONAB/211-265    AC H2PBA7.1
#=GS G1TLW9_RABIT/210-264    AC G1TLW9.1
#=GS Q4RNN8_TETNG/361-416    AC Q4RNN8.1
#=GS TBKB1_RAT/287-342       AC Q6DG50.1
#=GS Q8VDA2_RAT/129-185      AC Q8VDA2.1
#=GS H0Z8D8_TAEGU/64-121     AC H0Z8D8.1
#=GS G1QVJ4_NOMLE/211-265    AC G1QVJ4.1
#=GS F7GD78_MACMU/211-265    AC F7GD78.1
#=GS E7ENY2_HUMAN/131-187    AC E7ENY2.1
#=GS B7ZS25_XENLA/190-249    AC B7ZS25.1
#=GS G5B981_HETGA/212-266    AC G5B981.1
#=GS E6ZI15_DICLA/299-377    AC E6ZI15.1
#=GS G3RRH2_GORGO/211-265    AC G3RRH2.1
#=GS G3H5V0_CRIGR/1791-1843  AC G3H5V0.1
#=GS H2NVF5_PONAB/310-365    AC H2NVF5.1
#=GS Q3TNB4_MOUSE/128-184    AC Q3TNB4.1
#=GS G1U0B2_RABIT/207-260    AC G1U0B2.1
#=GS D2H3M5_AILME/212-266    AC D2H3M5.1
#=GS E7EW82_HUMAN/189-239    AC E7EW82.1
#=GS H7BX65_MOUSE/287-342    AC H7BX65.1
#=GS Q0VD25_BOVIN/162-218    AC Q0VD25.1
#=GS F7A092_MOUSE/151-198    AC F7A092.1
#=GS G3X0K7_SARHA/225-279    AC G3X0K7.1
#=GS H0WQY5_OTOGA/131-187    AC H0WQY5.1
#=GS G1PQ89_MYOLU/294-349    AC G1PQ89.1
#=GS H0XIS9_OTOGA/203-254    AC H0XIS9.1
#=GS F1RPR5_PIG/130-186      AC F1RPR5.1
#=GS G3NPU7_GASAC/257-306    AC G3NPU7.1
#=GS Q4R5I0_MACFA/130-186    AC Q4R5I0.1
#=GS E2RLT7_CANFA/226-278    AC E2RLT7.1
#=GS F1LQL4_RAT/224-277      AC F1LQL4.1
#=GS TANK_MOUSE/163-219      AC P70347.1
#=GS G7PKN6_MACFA/130-186    AC G7PKN6.1
#=GS E1BM04_BOVIN/286-341    AC E1BM04.1
#=GS H7C1Z1_HUMAN/9-67       AC H7C1Z1.1
#=GS G3WTC1_SARHA/148-204    AC G3WTC1.1
#=GS G3NI57_GASAC/261-317    AC G3NI57.1
#=GS G1QLY4_NOMLE/14-63      AC G1QLY4.1
#=GS F6ZSV9_XENTR/192-251    AC F6ZSV9.1
#=GS H2U837_TAKRU/251-306    AC H2U837.1
#=GS Q08CI3_DANRE/125-180    AC Q08CI3.1
#=GS E1C5I0_CHICK/130-185    AC E1C5I0.1
#=GS AZI2_BOVIN/212-266      AC Q3SYW5.1
#=GS G5BT21_HETGA/66-122     AC G5BT21.1
#=GS G3T829_LOXAF/100-156    AC G3T829.1
#=GS E7FGU2_DANRE/283-338    AC E7FGU2.1
#=GS D2HPY4_AILME/130-186    AC D2HPY4.1
#=GS G1NF49_MELGA/231-279    AC G1NF49.1
#=GS F7G3B1_MACMU/130-186    AC F7G3B1.1
#=GS F1RWJ4_PIG/286-341      AC F1RWJ4.1
#=GS F7GD69_MACMU/211-267    AC F7GD69.1
#=GS H9EZA5_MACMU/286-340    AC H9EZA5.1
#=GS F1PEY1_CANFA/166-222    AC F1PEY1.1
#=GS G1NEX6_MELGA/130-185    AC G1NEX6.1
#=GS G7MJZ3_MACMU/211-267    AC G7MJZ3.1
#=GS H3BD49_LATCH/289-346    AC H3BD49.1
#=GS G1TJ13_RABIT/204-261    AC G1TJ13.1
#=GS G1TNR4_RABIT/130-186    AC G1TNR4.1
#=GS H2QM81_PANTR/211-265    AC H2QM81.1
#=GS G3QIG2_GORGO/286-341    AC G3QIG2.1
#=GS E7EQA9_HUMAN/130-186    AC E7EQA9.1
#=GS Q4ZG76_HUMAN/97-153     AC Q4ZG76.1
#=GS F7DM24_MONDO/149-203    AC F7DM24.1
#=GS F7AZB3_ORNAN/134-188    AC F7AZB3.1
#=GS G3SNE1_LOXAF/286-341    AC G3SNE1.1
#=GS G1LDC5_AILME/305-361    AC G1LDC5.1
#=GS H0WT23_OTOGA/212-266    AC H0WT23.1
#=GS D3ZUI2_RAT/130-186      AC D3ZUI2.1
#=GS AZI2_PONAB/211-265      AC Q5RD40.1
#=GS G5BT31_HETGA/130-186    AC G5BT31.1
#=GS F1RRG1_PIG/15-69        AC F1RRG1.1
#=GS F6RX86_XENTR/230-277    AC F6RX86.1
#=GS F7IND3_CALJA/286-341    AC F7IND3.1
#=GS E1BU10_CHICK/218-275    AC E1BU10.1
#=GS F1P609_CANFA/306-361    AC F1P609.1
#=GS TBKB1_MOUSE/287-342     AC A2A9T0.1
#=GS F6YBK2_CALJA/130-186    AC F6YBK2.1
#=GS Q4JQQ1_XENLA/190-249    AC Q4JQQ1.1
#=GS H3DHU3_TETNG/245-294    AC H3DHU3.1
#=GS A2AR78_MOUSE/128-184    AC A2AR78.1
#=GS TBKB1_HUMAN/286-341     AC A7MCY6.1
#=GS G1NUH1_MYOLU/166-222    AC G1NUH1.1
#=GS H0VQS5_CAVPO/212-266    AC H0VQS5.1
#=GS Q8R383_MOUSE/128-184    AC Q8R383.1
#=GS H0Z8E4_TAEGU/127-183    AC H0Z8E4.1
#=GS AZI2_HUMAN/211-265      AC Q9H6S1.1
#=GS F6WYF7_CALJA/211-265    AC F6WYF7.1
#=GS Q6NW12_HUMAN/130-186    AC Q6NW12.1
#=GS Q8C2D3_MOUSE/128-184    AC Q8C2D3.1
#=GS H0XPA9_OTOGA/225-279    AC H0XPA9.1
#=GS H3CZR8_TETNG/254-312    AC H3CZR8.1
#=GS Q4SCJ8_TETNG/48-107     AC Q4SCJ8.1
#=GS G1TLY1_RABIT/286-332    AC G1TLY1.1
#=GS H2U838_TAKRU/247-302    AC H2U838.1
#=GS F1M101_RAT/148-204      AC F1M101.1
#=GS D3ZMC6_RAT/286-341      AC D3ZMC6.1
#=GS G7NYA6_MACFA/211-267    AC G7NYA6.1
#=GS H0Y0C3_OTOGA/286-341    AC H0Y0C3.1
#=GS G1KG46_ANOCA/279-355    AC G1KG46.1
#=GS G1NSE3_MYOLU/224-277    AC G1NSE3.1
#=GS F6ZGI5_ORNAN/212-266    AC F6ZGI5.1
#=GS A2AR76_MOUSE/162-218    AC A2AR76.1
#=GS G1M155_AILME/166-222    AC G1M155.1
#=GS H3BCD2_LATCH/213-270    AC H3BCD2.1
#=GS G7NH58_MACMU/284-330    AC G7NH58.1
#=GS G3X1J5_SARHA/285-340    AC G3X1J5.1
#=GS E6ZI16_DICLA/291-340    AC E6ZI16.1
#=GS H2PBA6_PONAB/211-267    AC H2PBA6.1
#=GS F1M696_RAT/146-202      AC F1M696.1
#=GS H0VSY8_CAVPO/151-206    AC H0VSY8.1
#=GS G9KSM5_MUSPF/10-65      AC G9KSM5.1
#=GS F8WHS7_MOUSE/145-201    AC F8WHS7.1
#=GS G1SKA1_RABIT/131-187    AC G1SKA1.1
#=GS H0YZD3_TAEGU/222-276    AC H0YZD3.1
#=GS E2RLY7_CANFA/131-187    AC E2RLY7.1
#=GS H2P7M8_PONAB/129-185    AC H2P7M8.1
#=GS H3C5J3_TETNG/121-175    AC H3C5J3.1
#=GS F6R2Z7_BOVIN/130-186    AC F6R2Z7.1
#=GS AZI2_MOUSE/224-278      AC Q9QYP6.1
#=GS AZI2_MACFA/211-265      AC Q4R3X1.1
#=GS H2QDA4_PANTR/286-341    AC H2QDA4.1
#=GS H2U839_TAKRU/249-304    AC H2U839.1
#=GS H2SKW7_TAKRU/123-177    AC H2SKW7.1
#=GS H2QIV9_PANTR/130-186    AC H2QIV9.1
#=GS G1M217_AILME/226-278    AC G1M217.1
#=GS G9KSD5_MUSPF/61-117     AC G9KSD5.1
#=GS E7EVA2_HUMAN/188-238    AC E7EVA2.1
#=GS F7AQP5_MACMU/286-341    AC F7AQP5.1
#=GS F1MAH0_RAT/129-185      AC F1MAH0.1
#=GS G1QF19_MYOLU/199-248    AC G1QF19.1
TANK_HUMAN/130-186                 .........PLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
#=GR TANK_HUMAN/130-186      SS    .........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX......................X.X.---B--TTS.....................
H2TA08_TAKRU/260-310               ........k-AGDEQVNLALAYTELTEELGRVRGLAITQSDLLRQVSQEPGRS--......................-.-.---------chfvfvq..............
F7E486_HORSE/212-266               ........r-LTISSDNMQNAYWELRREMSNLHLVTQVQAELLRKLKTPTAIK--......................K.A.YIPVGCMED.....................
H7C3L4_HUMAN/21-77                 .........PLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
F6SY96_MOUSE/1-53                  ........x------DNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSAAVKKD......................-.-.---------sssagrhrqers.........
A1L1J0_RAT/128-184                 .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
G7PU58_MACFA/284-337               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGKILRTLLQEQARSGE......................-.-.---------vgtircas.............
B2R7S3_HUMAN/130-186               .........PLLHERGNIEKAFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
F6ZGJ1_ORNAN/227-278               .......yf-----SDDMQYAYWELKKEMSNLHLVTQVQAELLRKLKTPTAIK--......................K.A.YAPVQCVED.....................
G1QMY3_NOMLE/130-186               .........PLLHERGNIEKTFWDLKEEFHRICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
D3DTT5_HUMAN/286-341               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGG......................Q.R.HSPLS-QRH.....................
G3NQ65_GASAC/108-163               ....sfdyq-------DMLNAFEAIQGKFRQIRSLTRRQKDHLKRFHGGSDASSD......................QwF.SMPIQCTD-r....................
D3Z7S3_MOUSE/77-131                ........q-GLHHSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSAAVK--......................K.A.CTPVGCVED.....................
F7FH52_MONDO/227-286               ......lyf-----SDNIHHAYRELKREMSNLHLVTQVQSELLRKFRTPSTIKKGks.................spaS.A.CAPVQCVED.....................
H2M9R1_ORYLA/265-323               .........KVGDEQVNLALAYTELTEELGRLRALSAKQTEILRKATQEQASPGG......................-.-.---------ehkhplrfntptq........
F7DUU2_XENTR/275-330               ........e-VGDDQVNLALAYTELTEEFYRLRDLTALQSRILRTLLEEQAAFLG......................Q.R.HSPPHH---hs...................
H3BCD3_LATCH/213-269               .....ltir-----SKFLQRAYWELKKEMSNLHLVTKVQSEVLRKLRATLTAANK.....................dS.L.SFPAQCVED.....................
F7AZG4_ORNAN/148-205               .......lt--SHERADLEKTFLEMKEELHRICMLTRMQTDHLSKFNLKNETARE.....................iQ.F.SMPIQCTDK.....................
F7BNJ6_HORSE/130-155               .........PLFHERGYIEKTFCDLKEEFHRICML--------------------......................-.-.---------.....................
B7ZS21_XENLA/190-249               ........a-LDCSRQGIEQIFSEMKEEFSHICRLTRKQSLHLNTFLLKKENSSEi...................plQ.C.SMPIQCTDE.....................
G1T830_RABIT/286-332               ........r-IGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARS--......................-.-.---------cge..................
F7DLM0_MONDO/149-205               ........s-LFNKREEIEKTFYEMKEEFHRICMLARAQREHLNRLNIQEPIPEI......................Q.F.SMPIQCTDE.....................
Q3UGW0_MOUSE/129-185               .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
G1KPN5_ANOCA/230-286               .......ee---HQSVNVQHAYWELKKEMSNLHLVTEVQAEMLKKLKLIPLGTRK.....................vP.S.CTPLQCVED.....................
G3QIP7_GORGO/145-201               .........PLLHERGNIEKTFWDLKEEFHRICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
G1T8F3_RABIT/212-266               ........r-VSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTPTTIK--......................K.A.YTPAACTED.....................
AZI2_RAT/224-277                   .......qg--PHHSDHMQHAYWELRREMANLHLVTRVQAELLRQLKTAAAGK--......................-.A.CTQVGCVED.....................
H2PBA7_PONAB/211-265               .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK--......................K.A.CAPVGCSED.....................
G1TLW9_RABIT/210-264               ....ktlyf-----SDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTPTTIK--......................K.A.YTPAACTED.....................
Q4RNN8_TETNG/361-416               ........l-FSSKRVNLALAYTELTEELGRLQALSTKQTEILRKASQDQASPV-......................Q.R.HSPIHHQRH.....................
TBKB1_RAT/287-342                  .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARNAG......................Q.R.HSPLS-QRH.....................
Q8VDA2_RAT/129-185                 .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
H0Z8D8_TAEGU/64-121                ........a-LNANRENLETIFQDMKEECHRICMLAREQTDQLSIFKIKPEPETE.....................iQ.F.SMPIQCTDK.....................
G1QVJ4_NOMLE/211-265               .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK--......................K.A.CAPVGCSED.....................
F7GD78_MACMU/211-265               .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK--......................K.A.CAPVGCSED.....................
E7ENY2_HUMAN/131-187               .........PLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
B7ZS25_XENLA/190-249               ........a-LDCSRQGIEQIFSEMKEEFSHICRLTRKQSLHLNTFLLKKENSSEi...................plQ.C.SMPIQCTDE.....................
G5B981_HETGA/212-266               .........RLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK--......................K.A.CTPVGCTED.....................
E6ZI15_DICLA/299-377               .........KVGDEQVNLALAYTELTEELGRLQALSSKQTEILRKASQEQASPAEwkpskvivvvssklqvsqikyfQ.R.HSPIHHQRH.....................
G3RRH2_GORGO/211-265               .........RLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK--......................K.A.CAPVGCSED.....................
G3H5V0_CRIGR/1791-1843             .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARNA-......................-.-.---------anayahae.............
H2NVF5_PONAB/310-365               .........RVGDDQVNLALAYTELMEELGRLRELSSLQGRILRTLLQEQARSGG......................Q.R.HSPLS-QRH.....................
Q3TNB4_MOUSE/128-184               .........PLHHERNNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
G1U0B2_RABIT/207-260               ........r-ASISRDNMQ-VYWELKREMSDLHLMTQVQAERLRKLKMPTAFK--......................K.A.CAPLTCAED.....................
D2H3M5_AILME/212-266               .........RLSISSDNMQSAYWELKREMSNLHLVTQVQAELLRKLKTPTTVK--......................K.A.CAPVGCMED.....................
E7EW82_HUMAN/189-239               .........PLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATAH......................-.-.---------leals................
H7BX65_MOUSE/287-342               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARNAG......................Q.R.HSPLS-QRH.....................
Q0VD25_BOVIN/162-218               .........PLFHERSYIEKTFRDLKEEFHRICLLAKAQKDHLSKLNVPSAAPET......................Q.C.SMPIQCTDK.....................
F7A092_MOUSE/151-198               ........q-GLHHSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSAAVKK-......................-.-.---------ghl..................
G3X0K7_SARHA/225-279               ....kilyf-----SDNMQHAYWELKREMSNLHLVTQVQAELLRKFKTSSIIK--......................K.A.CAPVQCVDD.....................
H0WQY5_OTOGA/131-187               .........PLFHERGNIEKTFWDLKEEFHRICMLAKAQKDHLSRLHIPDAATET......................Q.C.SLPIQCTDK.....................
G1PQ89_MYOLU/294-349               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQTRSGG......................Q.R.HSPLS-QRH.....................
H0XIS9_OTOGA/203-254               .........RLSISSDNMQHVYWELKREMSNLHLVTQVQ---LRRLKTPTSIK--......................K.P.CAPGGCIED.....................
F1RPR5_PIG/130-186                 .........PLFHERGYVEKTFWDLKEEFHRIRMLAKAQKDHLSKLNVADTAAET......................Q.C.SVPVQCTDK.....................
G3NPU7_GASAC/257-306               ........k-AGDEQVNLALAYTELTEELGRVRNLAVKQSDLLRHVSQEPGRTS-......................-.C.---------hryv.................
Q4R5I0_MACFA/130-186               .........PLLHERGSIEKTFWDLKEEFHRICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
E2RLT7_CANFA/226-278               ......lyf-----SDNMQNAYWELKREMSNLHLVTQVQAELLRKLKIPTTIK--......................K.A.CSPVGCMED.....................
F1LQL4_RAT/224-277                 .......qg--PHHSDHMQHAYWELRREMANLHLVTRVQAELLRQLKTAAAGK--......................-.A.CTQVGCVED.....................
TANK_MOUSE/163-219                 .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
G7PKN6_MACFA/130-186               .........PLLHERGSIEKTFWDLKEEFHRICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
E1BM04_BOVIN/286-341               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGG......................Q.R.HSPLS-QRH.....................
H7C1Z1_HUMAN/9-67                  .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKK-......................-.A.---------lsqnramrstapv........
G3WTC1_SARHA/148-204               ........s-LFSKREEIEKIFYEMKEEFRRICMLARAQRDYLNRLNIQEPIPEI......................Q.F.SMPIQCTDK.....................
G3NI57_GASAC/261-317               .........KVGDEQVNLALAYTELTEELGRLQALSSKQTEILRKASQEQASPVI......................Q.R.HSPIHHQRH.....................
G1QLY4_NOMLE/14-63                 .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARS--......................-.-.---------ggemgq...............
F6ZSV9_XENTR/192-251               ........r-LLCVWQGMEHVFSEMKEEFSQICRLTRKQSLQLNTLLSKKENSPDi...................plQ.C.SMPIQCTDE.....................
H2U837_TAKRU/251-306               .........KVGDEQVNLALAYTELTEELGRLQALSTKQTEILRKASQEQASPV-......................Q.R.HSPIQHQRH.....................
Q08CI3_DANRE/125-180               cemksedvl----------DTWQELQGTFQRIQSLTRRQKDHLKRIHKGNDTANE......................Q.F.SMPIQCTD-g....................
E1C5I0_CHICK/130-185               .......lp----ERENLETIFQEMKEECHRICMLAREQTDQLSKFKIKPEPETE.....................iQ.F.SMPIQCTDK.....................
AZI2_BOVIN/212-266                 .........RLSVSSDNMQSAYWELKREMSNLHLVTQVQAELLRKLKTPAAIK--......................K.A.CAPAGCMED.....................
G5BT21_HETGA/66-122                .........PLIHERDNLEKTFWGLKEEFHRVCMLAKAQKDHLSKLNIRDTATET......................Q.C.SMLVQCTDK.....................
G3T829_LOXAF/100-156               .........PLFHERDYIEKTFWDLKEEFHRICMLAKAQKEHLSKLNVPDTATET......................Q.C.SVPVQCTDK.....................
E7FGU2_DANRE/283-338               .........KVGDEQVNLALAYTELTEELGKLQALTSKQTEILRKASQEPASPV-......................Q.R.HSPVPHQRH.....................
D2HPY4_AILME/130-186               .........PLFHERAYIEKTFQDLKEEFHRICMLAKAQKDHLSKLNVPATATET......................Q.C.SLPIQCTDK.....................
G1NF49_MELGA/231-279               ...lhsffe-------SVQQAYWELKREMSNLQLVTEVQTEVLRKLKTNITATK-......................-.-.---------kgksv................
F7G3B1_MACMU/130-186               .........PLLHERGSIEKTFWDLKEEFHRICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
F1RWJ4_PIG/286-341                 .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGG......................Q.R.HSPLS-QRH.....................
F7GD69_MACMU/211-267               .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKG......................K.S.CAPVGCSED.....................
H9EZA5_MACMU/286-340               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGKILRTLLQEQARSGG......................Q.R.HSPLS----qr...................
F1PEY1_CANFA/166-222               .........PLFHERAYIEKTFQDLKEEFHRICMLAKAQKDHLSKLNVPATATET......................Q.C.SLPIQCTDK.....................
G1NEX6_MELGA/130-185               .......lp----ERENLETIFQEMKEECHRICMLAREQTDQLSKFKIKPEPETE.....................iQ.F.SMPIQCTDK.....................
G7MJZ3_MACMU/211-267               .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKG......................K.S.CAPVGCSED.....................
H3BD49_LATCH/289-346               .........KVGDEQVNLALAYTELTEELCRLRSVSTTQSEILRKLLQGQTHA--......................-.-.---------hahaeiterspmqr.......
G1TJ13_RABIT/204-261               qvsilsdhr---------QHAHWEL-REMSNLHLVTHVQAELPRKRKTPQVISE-......................-.-.---------algkdstklhltdf.......
G1TNR4_RABIT/130-186               .........PLFHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDTVIET......................Q.C.SVPIQCTDK.....................
H2QM81_PANTR/211-265               .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK--......................K.A.CAPVGCSED.....................
G3QIG2_GORGO/286-341               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGG......................Q.R.HSPLS-QRH.....................
E7EQA9_HUMAN/130-186               .........PLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
Q4ZG76_HUMAN/97-153                .........PLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
F7DM24_MONDO/149-203               ......ctf-----REEIEKTFYEMKEEFHRICMLARAQREHLNRLNIQEPIPEI......................Q.F.SMPIQCTDE.....................
F7AZB3_ORNAN/134-188               .......tf-----RADLEKTFLEMKEELHRICMLTRMQTDHLSKFNLKNETARE.....................iQ.F.SMPIQCTDK.....................
G3SNE1_LOXAF/286-341               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQTRSGG......................Q.R.HSPLS----qrp..................
G1LDC5_AILME/305-361               .........RVGDDQVNLALAYTELTEELGRLRETPLLPTTVLPSTRLASLPG--......................Q.R.HSPLS-QRHspa..................
H0WT23_OTOGA/212-266               .........RLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTPTSIK--......................K.A.CAPGGCFED.....................
D3ZUI2_RAT/130-186                 ......lqh---QRRDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
AZI2_PONAB/211-265                 .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK--......................K.A.CAPVGCSED.....................
G5BT31_HETGA/130-186               .........PLIHERDNLEKTFWDLKEEFHRVCMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPVQCTDK.....................
F1RRG1_PIG/15-69                   .........RLSTSSDNMQNAYWELKREMSNLHLVTQVQAELLRKLKTPTAIK--......................K.A.GTPAGYTED.....................
F6RX86_XENTR/230-277               .....lgfe------SSMRQAFWELKKEMSNLHLMTEVQGKVLRKLKAAVTASQ-......................-.-.---------kathv................
F7IND3_CALJA/286-341               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGG......................Q.R.HSPLS-QRH.....................
E1BU10_CHICK/218-275               ...qavqsf------ESVQQAYWELKREMSNLQLVTEVQTEVLRKLKTNITATKK.....................aA.S.SAPVQCVE-l....................
F1P609_CANFA/306-361               .........RVGDDQVNLALAYTELTEELRRVRLTKACPTLGQRAGSEEPASLPG......................Q.R.HSPLS-QRH.....................
TBKB1_MOUSE/287-342                .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARNAG......................Q.R.HSPLS-QRH.....................
F6YBK2_CALJA/130-186               .........PLLHERDNIEKTFWDLKEEFHRICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
Q4JQQ1_XENLA/190-249               ........a-LDCSRQGIEQIFSEMKEEFSHICRLTRKQSLHLNTFLLKKENSSEi...................plQ.C.SMPIQCTDE.....................
H3DHU3_TETNG/245-294               .........KVGDEQVNLALAYTELTEELGRLQALSTKQTEILRKASQDQASPA-......................-.-.---------slaga................
A2AR78_MOUSE/128-184               .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
TBKB1_HUMAN/286-341                .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGG......................Q.R.HSPLS-QRH.....................
G1NUH1_MYOLU/166-222               .........PLFHERSYIEKTFWDLKEEFHRICMLAKAQKDHLSKLNVSATAAET......................Q.C.SVPIQCTDK.....................
H0VQS5_CAVPO/212-266               ........g-LSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKASASIK--......................K.V.CTPVGCTED.....................
Q8R383_MOUSE/128-184               .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
H0Z8E4_TAEGU/127-183               .......is---PERENLETIFQDMKEECHRICMLAREQTDQLSIFKIKPEPETE.....................iQ.F.SMPIQCTDK.....................
AZI2_HUMAN/211-265                 .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK--......................K.A.CAPVGCSED.....................
F6WYF7_CALJA/211-265               .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTPTAIK--......................K.A.CAPVGCSED.....................
Q6NW12_HUMAN/130-186               .........PLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
Q8C2D3_MOUSE/128-184               .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
H0XPA9_OTOGA/225-279               .....mlhf----SIDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTPTSIK--......................K.A.CAPGGCFED.....................
H3CZR8_TETNG/254-312               ........k-AGDEQVNLALAYTELTEELGRVRDLAIKQSDLLRQGSQEPGRAK-......................-.-.---------msdldgrhspqpsv.......
Q4SCJ8_TETNG/48-107                ........k-AGDEQVNLALAYTELTEELGRVRDLAIKQSDLLRQGSQEPVPRSHp...................apQ.R.LSPTSSQRT.....................
G1TLY1_RABIT/286-332               ........r-IGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARS--......................-.-.---------cge..................
H2U838_TAKRU/247-302               .........KVGDEQVNLALAYTELTEELGRLQALSTKQTEILRKASQEQASPV-......................Q.R.HSPIQHQRH.....................
F1M101_RAT/148-204                 .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
D3ZMC6_RAT/286-341                 .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARNAG......................Q.R.HSPLS-QRH.....................
G7NYA6_MACFA/211-267               .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKG......................K.S.CAPVGCSED.....................
H0Y0C3_OTOGA/286-341               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARNGG......................Q.R.HSPLS-QRH.....................
G1KG46_ANOCA/279-355               .........KVGDDQVNLALAYTELTEELCRLRNLSSLQSQILRTLMQEQTISGG......................Q.R.HSPHS-QRHspaqqrrspapqctspaqqgr
G1NSE3_MYOLU/224-277               ......kiq----QSDDVQNVYWELKREMSNLHLVTQVQVELLRKLKTPTAIK--......................K.A.CAPVGFMED.....................
F6ZGI5_ORNAN/212-266               .....rpsi----QSDDMQYAYWELKKEMSNLHLVTQVQAELLRKLKTPTAIK--......................K.A.YAPVQCVED.....................
A2AR76_MOUSE/162-218               .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
G1M155_AILME/166-222               .........PLFHERAYIEKTFQDLKEEFHRICMLAKAQKDHLSKLNVPATATET......................Q.C.SLPIQCTDK.....................
H3BCD2_LATCH/213-270               .....eiqk----SEEFLQRAYWELKKEMSNLHLVTKVQSEVLRKLRATLTAANK.....................dS.L.SFPAQCVED.....................
G7NH58_MACMU/284-330               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGKILRTLLQEQARS--......................-.-.---------gir..................
G3X1J5_SARHA/285-340               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQAQRSG......................Q.R.HSPLS-QRH.....................
E6ZI16_DICLA/291-340               .........KVGDEQVNLALAYTELTEELGRLQALSSKQTEILRKASQEQASP--......................-.-.---------gkhlqy...............
H2PBA6_PONAB/211-267               .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKG......................K.S.CAPVGCSED.....................
F1M696_RAT/146-202                 .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
H0VSY8_CAVPO/151-206               .....lkff-----RDNLEKTFWDLKEEFHRICVLAKAQKDHLSKLNIPDVATET......................Q.C.SVPIQCTDK.....................
G9KSM5_MUSPF/10-65                 .........RVGDDQVNLALAYTELTEELGRLRELSALQGRILRTLLQEQARSGG......................Q.R.HSPLS-QRH.....................
F8WHS7_MOUSE/145-201               .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
G1SKA1_RABIT/131-187               .........PLFHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDTVIET......................Q.C.SVPIQCTDK.....................
H0YZD3_TAEGU/222-276               .......fh--------LQQTYWDLKREMSNLRVVTDKQAEILQKLKRNPLGTKKgc..................qsA.C.TAPVQCVD-l....................
E2RLY7_CANFA/131-187               .........PLFHERAYIEKTFQDLKEEFHRICMLAKAQKDHLSKLNVPATATET......................Q.C.SLPIQCTDK.....................
H2P7M8_PONAB/129-185               .........PLLHERGNIEKTFWDLKEEFHRICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
H3C5J3_TETNG/121-175               ......fvs------QDMLDAFEAIQGKFRQLQSLTRRQKDQLKRFRGGNETSSD.....................qQ.F.SMPIQCTD-r....................
F6R2Z7_BOVIN/130-186               .........PLFHERSYIEKTFRDLKEEFHRICLLAKAQKDHLSKLNVPSAAPET......................Q.C.SMPIQCTDK.....................
AZI2_MOUSE/224-278                 ........q-GLHHSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSAAVK--......................K.A.CTPVGCVED.....................
AZI2_MACFA/211-265                 .........KLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIK--......................K.A.CAPVGCSED.....................
H2QDA4_PANTR/286-341               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGG......................Q.R.HSPLS-QRH.....................
H2U839_TAKRU/249-304               .........KVGDEQVNLALAYTELTEELGRLQALSTKQTEILRKASQEQASPV-......................Q.R.HSPIQHQRH.....................
H2SKW7_TAKRU/123-177               ......vvs------QDMLDAFEAIQGKFRQIQSLTRRQKDQLKRFRGGNETSND......................Q.RfSMPIQCTD-r....................
H2QIV9_PANTR/130-186               .........PLLHERGNIEKTFWDLKEEFHRICMLAKAQKDHLSKLNIPDTATET......................Q.C.SVPIQCTDK.....................
G1M217_AILME/226-278               .....khfc------DNMQSAYWELKREMSNLHLVTQVQAELLRKLKTPTTVK--......................K.A.CAPVGCMED.....................
G9KSD5_MUSPF/61-117                .........PLFHERANIEKTFQDLKEEFHRLCMLAKAQKDHLSKLNVPATATDA......................Q.C.SLPIQCTDK.....................
E7EVA2_HUMAN/188-238               .........PLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATAH......................-.-.---------leals................
F7AQP5_MACMU/286-341               .........RVGDDQVNLALAYTELTEELGRLRELSSLQGKILRTLLQEQARSGG......................Q.R.HSPLS-QRH.....................
F1MAH0_RAT/129-185                 .........PLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDT......................Q.C.SVPIQCTDK.....................
G1QF19_MYOLU/199-248               .........RLSISSDEMQNAYWELKGEMSNLHLVTQVQIE----LKTPTAIK--......................K.A.CAP------ylgkd................
#=GC SS_cons                       .........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX......................X.X.---B--TTS.....................
#=GC seq_cons                      ..........lhccpsNlppsahELKEEhp+lphLopsQs-hLpKLphssststt......................p.t.ssPlpCp-c.....................
//
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