GenomeNet

Database: Pfam
Entry: TEBP_beta
LinkDB: TEBP_beta
Original site: TEBP_beta 
#=GF ID   TEBP_beta
#=GF AC   PF07404.7
#=GF DE   Telomere-binding protein beta subunit (TEBP beta)
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_20928 (release 10.0)
#=GF GA   20.70 20.70;
#=GF TC   20.90 90.10;
#=GF NC   19.00 20.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9875850
#=GF RT   Crystal structure of the Oxytricha nova telomere end binding
#=GF RT   protein complexed with single strand DNA. 
#=GF RA   Horvath MP, Schweiker VL, Bevilacqua JM, Ruggles JA, Schultz SC; 
#=GF RL   Cell 1998;95:963-974.
#=GF DR   INTERPRO; IPR010874;
#=GF DR   SCOP; 1jb7; fa;
#=GF CC   This family consists of several telomere-binding protein beta
#=GF CC   subunits which appear to be specific to the family Oxytrichidae.
#=GF CC   Telomeres are specialised protein-DNA complexes that compose the
#=GF CC   ends of eukaryotic chromosomes. Telomeres protect chromosome
#=GF CC   termini from degradation and recombination and act together with
#=GF CC   telomerase to ensure complete genome replication. TEBP beta
#=GF CC   forms a complex with TEBP alpha and this complex is able to
#=GF CC   recognise and bind ssDNA to form a sequence-specific, telomeric
#=GF CC   nucleoprotein complex that caps the very 3' ends of chromosomes
#=GF CC   [1]. 
#=GF SQ   18
#=GS Q9GNR9_OXYTR/1-229  AC Q9GNR9.1
#=GS TEBB_STYMT/1-381    AC P29548.1
#=GS Q9GNS6_OXYTR/1-374  AC Q9GNS6.1
#=GS Q9NCP6_STYLE/1-382  AC Q9NCP6.1
#=GS J9J2H2_9SPIT/8-302  AC J9J2H2.1
#=GS Q9GNS2_OXYTR/1-194  AC Q9GNS2.1
#=GS TEBB_STENO/1-372    AC P16458.1
#=GS TEBB_STENO/1-372    DR PDB; 1PH1 B; 8-224;
#=GS TEBB_STENO/1-372    DR PDB; 1PH5 B; 9-224;
#=GS TEBB_STENO/1-372    DR PDB; 1PH8 B; 9-224;
#=GS TEBB_STENO/1-372    DR PDB; 1PH4 B; 9-224;
#=GS TEBB_STENO/1-372    DR PDB; 1PH2 B; 9-224;
#=GS TEBB_STENO/1-372    DR PDB; 1OTC B; 10-222;
#=GS TEBB_STENO/1-372    DR PDB; 2I0Q B; 9-224;
#=GS TEBB_STENO/1-372    DR PDB; 1PH3 B; 9-224;
#=GS TEBB_STENO/1-372    DR PDB; 1PH6 B; 8-224;
#=GS TEBB_STENO/1-372    DR PDB; 1PH9 B; 9-224;
#=GS TEBB_STENO/1-372    DR PDB; 1JB7 B; 9-224;
#=GS TEBB_STENO/1-372    DR PDB; 1PH7 B; 9-224;
#=GS TEBB_STENO/1-372    DR PDB; 1PA6 B; 9-224;
#=GS TEBB_STENO/1-372    DR PDB; 1PHJ B; 10-224;
#=GS Q9GNS0_OXYTR/1-194  AC Q9GNS0.1
#=GS Q9GNR7_STYMT/1-196  AC Q9GNR7.1
#=GS Q9GNS1_OXYTR/1-230  AC Q9GNS1.1
#=GS Q9GNS5_OXYTR/1-375  AC Q9GNS5.1
#=GS E2I6F1_STYLE/1-224  AC E2I6F1.1
#=GS Q9GNR8_OXYTR/1-229  AC Q9GNR8.1
#=GS Q9GNR5_STYMT/1-196  AC Q9GNR5.1
#=GS A8HG51_OXYTR/1-374  AC A8HG51.1
#=GS J9IFJ9_9SPIT/1-375  AC J9IFJ9.1
#=GS J9EDK6_9SPIT/5-186  AC J9EDK6.1
#=GS Q9GNR6_STYMT/1-237  AC Q9GNR6.1
Q9GNR9_OXYTR/1-229             .......-------.------------------------------.-----------------------------------------------------------------------------------------------..-------------TIQHFRHQALQQSLAKNLKQENIPDIAKVTGGD---KKAKVDAGIVRA......S......TSKGDEFSDFSF.KEGNTATIRIQDIFVQEKGKDALSKLGGEGDV-......KVKG...GARGKAKAASKSA.KGKKVSAKKADV-AAADVRKSVDKIVKYTPNKPSSRKETPQKSQSVPAAGKSSAKKTATGSKKTLPANPSPSGKKSTKTTDQMTMAQFKRYLEWHEKKKGGKTSSGGKVLGKRSAGKASATSG.............................
TEBB_STYMT/1-381               .......MSKGQ-A.QQQSAFKQLFTEFFNLGGDFSKVSKDLKKP.LKTYVKESYPHFLVTDGYFFVQPHFTKEAVAEFHQKFPNVNIVDLHDKVIVINSWSLELRRVNSAEVFTSYANLEARLVVHSFKPNLQERLNPTR..YPVNLFRDDEFKTIIQHFRHQALQQSIAKNTKQESLPDISKLSGADAAGKKTKVDGGIVKT......G......ASKGDEFADFSF.KEGSTAVLKIQDIFVQEKGKDALKRIQD-QQVEsvqvqpKVRG...GAKGKKKAATKSA.-TKKTVAAKK-TAESADVRKSVDKIVKYTPNKPSSRKETPQKSQSAPAAGKSSAKRTTTGSKTKIPANPSPSGKKSTKTTDQMTMAQFKKYLDWHEKKKGGKTSSGGKVLGKRSAGKASATSG.............................
Q9GNS6_OXYTR/1-374             .......MSKSQQV.QQQSAFKQLYTELFNNGGDFGKVSNNLKKP.LKCYVKESYPHFLVTDGYFFVTPYFTKEAVTEFHSKFPNVNIVDLHDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTR..YPVNLYRDDEFKTTIQHFRHQALQQSLAKNLKQENIPDIAKVTGGD---KKAKVDAGIVRA......S......TSKGDEFSDFSF.KEGNTATIRIQDIFVQEKGKDALSKLGGEGDV-......KVKG...GARGKAKAASKSA.KGKKVSAKKADV-AAADVRKSVDKIVKYTPNKPSSRKETPQKSQSVPAAGKSSAKKTATGSKKTLPANPSPSGKKSTKTTDQMTMAQFKRYLEWHEKKKGGKTSSGGKVLGKRSAGKASATSG.............................
Q9NCP6_STYLE/1-382             .......MSKGQ-V.QQQSAFKQLFTEFFNQGGDFNKVSKALKKP.LKTYVKESYPHFLVTDGYFFVQPHFTKEAVAEFHQKFPNVNIVDLHDKVIVINTWSLELRRVNSAEVFTSYANLEARLVVHSFKPNLQERLNPTR..YPVNLFRDDEFKTIIQHFRHQALQQSIAKNTKQESLPDISKLSGAEAAGKKTKVDGGIVRT......G......ASKGDEFADFSF.KEGNTAVVKIQDIFVQEKGKDALKRIQDAQDQQqvqaqpKVKG...GAKGKKKAASKSA.-QKKTVAKKA-AGESADVRKSVDKIVKYTPNKPSSRKETPQKSQSAPAAGKSSAKKTATGAKTKIPANPSPSGKKSTKTTDQMTMAQFKKYLDWHEKKKGGKTSSGGKVLGKRSAGKASATSG.............................
J9J2H2_9SPIT/8-302             ..nsnpa----KQA.KSSSAFKTLFNELLSNQGDYNKLPDNLKRAkIRCQVRETYPKLLISDGSFFIAGYITKECQNKCEQK--KVKITDLKDGLILITKWNVELTLVNSAEEFTSYSGIEMRVIIHEFRVNQEEDLKMSK..FPTNLYRDDEVKASILHFIQAQRLQQLNNLVAQDKEISLGTILAK--PKTKTELNESLLRSnnvislSgkkvdvSADCDQFTDFGFdKAKRTPVLTMQEIFIAEKGAEALRKLNINLQVQ......RQKDepqHAKGKRQTT----.---------------------------------------------------------------------------------------------------------------------------qdlqndqgqdeisvgkvkksltvskpket
Q9GNS2_OXYTR/1-194             .......MSKSQQV.QQQSAYKQLYTELFNNGGDFGKVSNNLKKP.LKCYVKESYTHFLVTDGYFFVTPYFTKEAVTEFHSKFPNVNIVDLHDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTR..YPVNLYRDDEFKTTIQHFRHQALQQSLAKNIKQENIPDIAKVTGGD---KKAKVDAGIVRA......S......TSK---------.---------------------------------......----...-------------.---------------------------------------------------------------------------------------------------------------------------.............................
TEBB_STENO/1-372               .......MSKGASApQQQSAFKQLYTELFNNEGDFSKVSSNLKKP.LKCYVKESYPHFLVTDGYFFVAPYFTKEAVNEFHAKFPNVNIVDLTDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTR..YPVNLFRDDEFKTTIQHFRHTALQAAINKTVKGDNLVDISKV--ADAAGKKGKVDAGIVKA......S......ASKGDEFSDFSF.KEGNTATLKIADIFVQEKGKDALNKAADHTDGA......KVKG...GAKGKGKAAAKAA.KGKKLSAKKGDS-SAADVRKSVDKIVKYTPSK-GSRKDTPQKSQ-APAAGKSSAKK---GGKKAVPSAPSPSGKKSALTTDKMTMAQFVKYLDWHEKKKGGKVSSGGKVLGKRSAGKASATSG.............................
#=GR TEBB_STENO/1-372    SS    .......XXXXXXXXX---HHHHHHHHHHTTTT-TTCS-GGGTS-.EEEEEEEESSSEEEESSSEEE-EEE-HHHHHHHHHHSTT--GGG-TTSEEEEEEEEEEEEE--TTT-SS-BTTEEEEEEEEEEEEETTS----SS..--EEGGG-HHHHHHHHHHHHHHHHHHHHHHS-ST----HHHH--SSCTT----GGGGEEES......S......S-SSSB----SS.---------TTHHHHHHH-XXXXXXXXXXXXXX......XXXX...XXXXXXXXXXXXX.XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX-XXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.............................
Q9GNS0_OXYTR/1-194             .......MSKSQQV.QQQSAFKQLYAELFNNGGDFGKVSNNLKKP.LKCYVKESYPHFLVTDGYFFVTPYFTKEAVTEFHSKFPNVNIVDLHDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTR..YPVNLYRDDEFKTTIQHFRHQALQQSLAKNLKQENIPDIAKVTGGD---KKAKVDAGIVRA......S......TSK---------.---------------------------------......----...-------------.---------------------------------------------------------------------------------------------------------------------------.............................
Q9GNR7_STYMT/1-196             .......MSKGQ-A.QQQSAFKQLFTEFFNLGGDFSKVSKDLKKP.LKTYVKESYPHFLVTDGYFFVQPHFTKEAVAEFHQKFPNVNIVDLHDKVIVINSWSLELRRVNLAEVFTSYANLEARLVVHSFKPNLQERLNPTR..YPVNLFRDDEFKTIIQHFRHQALQQSIAKNTKQESLPDISKLSGADAAGKKTKVDGGIVKT......G......ASK---------.---------------------------------......----...-------------.---------------------------------------------------------------------------------------------------------------------------.............................
Q9GNS1_OXYTR/1-230             .......-------.------------------------------.-----------------------------------------------------------------------------------------------..-------------TIQHFRHQALQQSLAKNLRQENIPDIAKVTGGD---KKAKVDAGIVRA......S......TSKGDEFSDFSF.KEGNTATIRIQDIIVQEKGKDALSKLGGEGDV-......KVKG...GARGKAKAASKSAaRGKKGSAKKADVGASADVRKSVDKIVKYTPNKPSSRKETPQKSQSVPA-GKSSAKKTITGSKKTLPANPSPSGKKSTKTTDQMTMAQFKRYLEWHEKKNVGKTSSGGKVLGKRSAGKASATSG.............................
Q9GNS5_OXYTR/1-375             .......MSKSQQV.QQQSAFKQLYTELFNNGGDFGKVSNNLKKP.LKCYVKESYPHFLVTDGYFFVTPYFTKEAVTEFHSKFPNVNIVDLHDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTR..YPVNLYRDDEFKTTIQHFRHQALQQSLAKNLKQENIPDIAKVTGGD---KKAKVDAGIVRA......S......TSKGDEFSDFSF.KEGNTATIRIQDIFVQEKGKDALSKLGGEGDV-......KVKG...GARGKAKAASKSAaRGKKGSAKKADVGASADVRKSVDKIVKYTPNKPSSRKETPQKSQSVPA-GKSSAKKTTTGSKKTLPANPSPSGKKSTKTTDQMTMAQFKRYLEWHEKKNVGKTSSGGKVLGKRSAGKASATSG.............................
E2I6F1_STYLE/1-224             .......-------.-----FKQLFTEFFNLGGDFSKVSKDLKKP.LKTYVKESYPHFLVTDGYFFVQPHFTKEAVAEFHQKFPNVNIVDLHDKVIVINTWSLELRRVNSAEVFTSYANLEARLVAHSFKPNLQERLNPTR..YPVNLFRDDEFKTIIQHFRHQALQQSIAKNTKQESLPDISKLSGADAAGKKTKVDGGIVKT......G......ASKGDEFADFSF.KEGSTAVLKIQDIFVQEKGKDALKRIQDA----......----...-------------.---------------------------------------------------------------------------------------------------------------------------q............................
Q9GNR8_OXYTR/1-229             .......-------.------------------------------.-----------------------------------------------------------------------------------------------..-------------TIQHFRHQALQQSLAKNLKQENIPDIAKVTGGD---KKAKVDAGIVRA......S......TSKGDEFSDFSF.KEGNTATIRIQDIFVQEKGKDALSKLGGEGDV-......KVKG...GARGKAKAASKSA.KGKKVSAKKADV-AAADMRKSVDKIVKYTPNKPSSRKETPQKSQSVPAAGKSSAKKTATGSKKTLPANPSPSGKKSTKTTDQMTMAQFKRYLEWHEKKKGGKTSSGGKVLGKRSAGKASATSG.............................
Q9GNR5_STYMT/1-196             .......MSKGQ-A.QQQSAFKQLFTEFFNLGGDFSKVSKDLKKP.LKTYVKQSYPHFLVTDGYFFVQPHFTKEAVAEFHQKFPNVNIVDLHDKVIVINSWSLELRRVNSAEVFTSYANLEARLVVHSFKPNLQERLNPTR..YPVNLFRDDEFKTIIQHFRHQALQQSIAKNTKQESLPDISKLSGADAAGKKTKVDGGIVKT......G......ASK---------.---------------------------------......----...-------------.---------------------------------------------------------------------------------------------------------------------------.............................
A8HG51_OXYTR/1-374             .......-SKSQQV.QQQSAFKQLYTELFNNGGDFGKVSNNLKKP.LKCYVKESYPHFLVTDGYFFVTPYFTKEAVTEFHSKFPNVNIVDLHDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTR..YPVNLYRDDEFKTTIQHFRHQALQQSLAKNLKQENIPDIAKVTGGD---KKAKVDAGIVRA......S......TSKGDEFSDFSF.KEGNTATIRIQDIFVQEKGKDALSKLGGEGDV-......KVKG...GARGKAKAASKSAaRGKKGSAKKADVGASADVRKSVDKIVKYTPNKPSSRKETPQKSQSVPA-GKSSAKKTTTGSKKTLPANPSPSGKKSTKTTDQMTMAQFKRYLEWHEKKNVGKTSSGGKVLGKRSAGKASATSG.............................
J9IFJ9_9SPIT/1-375             .......MSKSQQV.QQQSAFKQLYTELFNNGGDFGKVSNNLKKP.LKCYVKESYPHFLVTDGYFFVTPYFTKEAVTEFHSKFPNVNIVDLHDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTR..YPVNLYRDDEFKTTIQHFRHQALQQSLAKNLKQENIPDIAKVTGGD---KKAKVDAGIVRA......S......TSKGDEFSDFSF.KEGNTATIRIQDIFVQEKGKDALSKLGGEGDV-......KVKG...GARGKAKAASKSAaRGKKGSAKKADVGASADVRKSVDKIVKYTPNKPSSRKETPQKSQSVPA-GKSSAKKTTTGSKKTLPANPSPSGKKSTKTTDQMTMAQFKRYLEWHEKKNVGKTSSGGKVLGKRSAGKASATSG.............................
J9EDK6_9SPIT/5-186             ylfener-------.-----LKPIIASYINSNFDFEAIPLNLRKH.MRLSVQENIATFWVNDGFHFLEAQFTKDAINEFRKSYSHIKFQSLKGGIMFISKWSLKIKECDSRKVYTSYQNMQIQLVIESFKPLLHEKPVRHQlvNAINIFHDEDVQIYIRHKRHEFIKEILNTHI------------------------------......-......------------.---------------------------------......----...-------------.---------------------------------------------------------------------------------------------------------------------------yksqelkgrdfampsikaikgs.......
Q9GNR6_STYMT/1-237             .......-------.------------------------------.-----------------------------------------------------------------------------------------------..-------------IIQHFRHQALQQSIAKNTKQESLPDISKLSGADAAGKKTKVDGGIVKT......G......ASKGDEFADFSF.KEGSTAVLKIQDIFVQEKGKDALKRIQD-QQVEsvqvqpKVRG...GAKGKKKAATKSA.-TKKTVAAKK-TAESADVRKSVDQIVKYTPNKPSSRKETPQKSQSAPAAGKSSAKRTTTGSKTKIPANPSPSGKKSTKTTDQMTMAQFKKYLDWHEKKKGGKTSSGGKVLGKRSAGKASATSG.............................
#=GC SS_cons                   .......XXXXXXXXX---HHHHHHHHHHTTTT-TTCS-GGGTS-.EEEEEEEESSSEEEESSSEEE-EEE-HHHHHHHHHHSTT--GGG-TTSEEEEEEEEEEEEE--TTT-SS-BTTEEEEEEEEEEEEETTS----SS..--EEGGG-HHHHHHHHHHHHHHHHHHHHHHS-ST----HHHH--SSCTT----GGGGEEES......S......S-SSSB----SS.---------TTHHHHHHH-XXXXXXXXXXXXXX......XXXX...XXXXXXXXXXXXX.XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX-XXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.............................
#=GC seq_cons                  ........SKup.s.QQQSAFKQLaTEhFN.GGDFuKVSpsLKKP.LKsYVKESYPHFLVTDGYFFVpPaFTKEAVsEFHpKFPNVNIVDLHDKVIVINsWSLELRRVNSAEVFTSYANLEARLlVHSFKPNLQERLNPTR..YPVNLaRDDEFKToIQHFRHQALQQSLAKNlKQEslPDIuKloGuD...KKsKVDuGIVRu......S......sSKGDEFuDFSF.KEGsTAsl+IQDIFVQEKGKDALp+ltsttps.......KV+G...GA+GKtKAAsKuA..tKKhsAtKt.s.tuADhRKSVDpIVKYTPsK.uSRK-TPQKSQ.sPA.GKSSAK+...GuKptlPusPSPSGKKSshTTDpMTMAQFh+YL-WHEKKpsGKsSSGGKVLGKRSAGKASATSG.............................
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