GenomeNet

Database: Pfam
Entry: TEBP_beta
LinkDB: TEBP_beta
Original site: TEBP_beta 
#=GF ID   TEBP_beta
#=GF AC   PF07404.9
#=GF DE   Telomere-binding protein beta subunit (TEBP beta)
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_20928 (release 10.0)
#=GF GA   20.70 20.70;
#=GF TC   61.40 61.40;
#=GF NC   18.50 17.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9875850
#=GF RT   Crystal structure of the Oxytricha nova telomere end binding
#=GF RT   protein complexed with single strand DNA. 
#=GF RA   Horvath MP, Schweiker VL, Bevilacqua JM, Ruggles JA, Schultz SC; 
#=GF RL   Cell 1998;95:963-974.
#=GF DR   INTERPRO; IPR010874;
#=GF DR   SCOP; 1jb7; fa;
#=GF CC   This family consists of several telomere-binding protein beta
#=GF CC   subunits which appear to be specific to the family Oxytrichidae.
#=GF CC   Telomeres are specialised protein-DNA complexes that compose the
#=GF CC   ends of eukaryotic chromosomes. Telomeres protect chromosome
#=GF CC   termini from degradation and recombination and act together with
#=GF CC   telomerase to ensure complete genome replication. TEBP beta
#=GF CC   forms a complex with TEBP alpha and this complex is able to
#=GF CC   recognise and bind ssDNA to form a sequence-specific, telomeric
#=GF CC   nucleoprotein complex that caps the very 3' ends of chromosomes
#=GF CC   [1]. 
#=GF SQ   7
#=GS J9IFJ9_9SPIT/1-375        AC J9IFJ9.1
#=GS A0A078AVL9_STYLE/1-381    AC A0A078AVL9.1
#=GS J9EDK6_9SPIT/5-186        AC J9EDK6.1
#=GS A0A078AC33_STYLE/116-420  AC A0A078AC33.1
#=GS A0A077ZYS3_STYLE/1-334    AC A0A077ZYS3.1
#=GS J9J2H2_9SPIT/8-302        AC J9J2H2.1
#=GS A0A078AEB0_STYLE/1-211    AC A0A078AEB0.1
J9IFJ9_9SPIT/1-375                   ..........................................MSKSQQVQQQSAFKQLYTELFNNGGDFGKVSNNLKKP.LKCYVKESYPHFLVTDGYFFVTPYFTKEAVTEFHSKF...PNVNIVDLHDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTR..Y..PVNLYRDDEFKTTIQHFRHQALQQSLAKNLKQENIPDIAKVTGGD---KKAK.VDA.GIV....R..A......S......TSKGDE..FS.D...FSF.K.....E.GN.TATIRIQDIFVQEKGKDALSKLGGEGDV-......KVKG...GARGKAKAASKSAaRGKKGSAKKADVGASADVRKSVDKIVKYTPNK.......PSSRKETPQKSQSVPA-GKSSAKKTTTGSKKTLPANPSPS.GKKSTKTTDQMTMAQFKRYLEWHEKKNVGKTSSGGKVLGKRSAGKASATSG.................................................
A0A078AVL9_STYLE/1-381               ..........................................MSKGQ-AQQQSAFKQLFTEFFNLGGDFSKVSKDLKKP.LKTYVKESYPHFLVTDGYFFVQPHFTKEAVAEFHQKF...PNVNIVDLHDKVIVINTWSLELRRVNSAEVFTSYANLEARLVVHSFKPNLQERLNPTR..Y..PVNLFRDDEFKTIIQHFRHQALQQSIAKNTKQESLPDISKLSGADAAGKKTK.VDG.GIV....K..T......G......ASKGDE..FA.D...FSF.K.....E.GS.TAVLKIQDIFVQEKGKDALKRIQDA-QVDsvqaqpKVKG...GAKGKKKAATKSA.-TKKTVAAKK-TAESADVRKSVDKIVKYTPNK.......PSSRKETPQKSQSAPAAGKSSAKRTTTGSKTKIPANPSPS.GKKSTKTTDQMTMAQFKKYLDWHEKKKGGKTSSGGKVLGKRSAGKASATSG.................................................
J9EDK6_9SPIT/5-186                   ...................................ylfener------------LKPIIASYINSNFDFEAIPLNLRKH.MRLSVQENIATFWVNDGFHFLEAQFTKDAINEFRKSY...SHIKFQSLKGGIMFISKWSLKIKECDSRKVYTSYQNMQIQLVIESFKPLLHEKPVRHQlvN..AINIFHDEDVQIYIRHKRHEFIKEILNTHI----------------------.---.---....-..-......-......------..--.-...---.-.....-.--.-----------------------------......----...-------------.--------------------------------.......----------------------------------------.---------------------------------------------------yksqelkgrdfampsikaikgs...........................
A0A078AC33_STYLE/116-420             hsqqysqqnqyqfkdekypiklmlndflrqkqgifkseiiet-----------------------------------DC.LQLAIQETFPLFILTDNYHFINACLSTELWEKLKVKQlskTKLKLCDMLNMKLKITKLQLQLRQVNSKEIFTSFASLEVRLIIHDTEILFNEQFAKRK..F..TNSVFKDEEIRTLIHMKFHHLMKQHL-QATKTALLVNIPKKIFDIKKQKKVSiIDV.SV-....Y..V......Q......PDKPEEkiIAnDgtvIPF.KwinqqE.NLvDNVIEISAIMIQERGQDYYNSLVERRKKQ......----...-------------.--------------------------------.......----------------------------------------.---------------------------------------------------eemkkqrdqreqrsstppryhqftrqkeyadkikikhqvkkdknn....
A0A077ZYS3_STYLE/1-334               ........................................ml---------------------SKNGEFSKIGDFKKAK.IRCYVKETYPKFLISDGSYFISGYFTKDWLKNSE--K...NKIRITDLNEGLILINKWSIELAKVNSAEDFTSYSGIEMRLIIHDFKVNKDEDLKMSK..F..PTNLYRDDEVKSRVLEFIADQRSEKLAEKVQKDTIIDSSLLNQSKNTRRNVD.LRKlNILsledKqlT......L......NAEDDT..FN.G...FFF.D.....SlPK.TQILTQQELFILEKGQEALRKANINLQNQ......RARE...EPMQQKKSADKTKlKIEPSSPQKGDN-SNVKLKKSLA-VSKPTQGGvsklkitTTYLKDDPTEVRKTR--SKSKSTKTTTTTKSKIVQSTSKSpGKQSVVSTSK-----------------------------------------spkk.............................................
J9J2H2_9SPIT/8-302                   .....................................nsnpa----KQAKSSSAFKTLFNELLSNQGDYNKLPDNLKRAkIRCQVRETYPKLLISDGSFFIAGYITKECQNKCEQK-...-KVKITDLKDGLILITKWNVELTLVNSAEEFTSYSGIEMRVIIHEFRVNQEEDLKMSK..F..PTNLYRDDEVKASILHFIQAQRLQQLNNLVAQDKEISLGTILAK--PKTKTE.LNE.SLL....R..SnnvislSgkkvdvSADCDQ..FT.D...FGFdK.....A.KR.TPVLTMQEIFIAEKGAEALRKLNINLQVQ......RQKDepqHAKGKRQTT----.--------------------------------.......----------------------------------------.---------------------------------------------------qdlqndqgqdeisvgkvkksltvskpket....................
A0A078AEB0_STYLE/1-211               .................................mssthyydn----------ERIKPLVTSFINANFDFEAIPLQLKKS.MRVGVQEHIAFFWVNDGYHFLEAVFTKEAVNEFRKNW...PHLKFIGLKEKILLITKWSLRIREADSRKLFTSYQNLQIQIVIEGFKPILHEKPNPKQ..HfqATNIYHDEEIQTYLRHKRHEMIRGFLSN------------------------.---.---....-..-......-......------..--.-...---.-.....-.--.-----------------------------......----...-------------.--------------------------------.......----------------------------------------.---------------------------------------------------hiffrtkgenklelpsiklikkqqsqyellkvqndsssdnemldladeq
#=GC seq_cons                        ......................................................hK.lhsphhstshDFptls.pLK+s.l+shVpEoaPpFlloDGaaFlpuhFTKEslsch+pph...s+l+lsDL+-tlllIsKWSLcL+cVNStElFTSYuslEhRLlIHsFKs.hpEchs.p+..a..ssNla+D-El+ohIpHhhHphhpppLspthtpt...s.shh..t....ppsp.lp..sl.....h..s.............sscs-p..hs.s...h.F.c.....t....s.hlp.ptlhl.E+Gt-hhpph..t.p.................................................................................................................................................................................................................
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