GenomeNet

Database: Pfam
Entry: TM1506
LinkDB: TM1506
Original site: TM1506 
#=GF ID   TM1506
#=GF AC   PF08973.9
#=GF DE   Domain of unknown function (DUF1893)
#=GF PI   DUF1893;
#=GF AU   Mistry J, Sammut SJ, Iyer, LM
#=GF SE   pdb_1vk9
#=GF GA   20.50 20.50;
#=GF TC   20.70 32.00;
#=GF NC   20.20 19.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   18275082
#=GF RT   Crystal structure of an ADP-ribosylated protein with a cytidine
#=GF RT   deaminase-like fold, but unknown function (TM1506), from
#=GF RT   Thermotoga maritima at 2.70 A resolution.
#=GF RA   Xu Q, Kozbial P, McMullan D, Krishna SS, Brittain SM, Ficarro
#=GF RA   SB, DiDonato M, Miller MD, Abdubek P, Axelrod HL, Chiu HJ,
#=GF RA   Clayton T, Duan L, Elsliger MA, Feuerhelm J, Grzechnik SK, Hale
#=GF RA   J, Han GW, Jaroszewski L, Klock HE, Morse AT, Nigoghossian E,
#=GF RA   Paulsen J, Reyes R, Rife CL, van den Bedem H, White A, Hodgson
#=GF RA   KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA;
#=GF RL   Proteins. 2008;71:1546-1552.
#=GF RN   [2]
#=GF RM   21890906
#=GF RT   Evolution of the deaminase fold and multiple origins of
#=GF RT   eukaryotic editing and mutagenic nucleic acid deaminases from
#=GF RT   bacterial toxin systems.
#=GF RA   Iyer LM, Zhang D, Rogozin IB, Aravind L;
#=GF RL   Nucleic Acids Res. 2011; [Epub ahead of print]
#=GF DR   INTERPRO; IPR015067;
#=GF CC   A member of the deaminase fold that binds an unknown ligand in 
#=GF CC   the crystal structure. The protein is ADP-ribosylated at a
#=GF CC   conserved aspartate [1]. Contextual analysis suggests that the
#=GF CC   domain  is likely to bind NAD or ADP ribose either to sense
#=GF CC   redox states or to function as a regulatory ADP
#=GF CC   ribosyltransferase [2].
#=GF SQ   142
#=GS I0GII0_CALEA/10-143      AC I0GII0.1
#=GS A0A151EUE4_9EURY/13-143  AC A0A151EUE4.1
#=GS A6TMK8_ALKMQ/6-136       AC A6TMK8.1
#=GS F0R096_BACSH/3-132       AC F0R096.1
#=GS A0A086ZT33_9BIFI/18-152  AC A0A086ZT33.1
#=GS E2SLS4_9FIRM/4-131       AC E2SLS4.1
#=GS A0A096BHW2_9CLOT/6-136   AC A0A096BHW2.1
#=GS H1XR58_9BACT/3-119       AC H1XR58.1
#=GS L1N559_9BACT/4-103       AC L1N559.1
#=GS R6S1N3_9BACE/4-133       AC R6S1N3.1
#=GS R5VFC2_9BACT/3-132       AC R5VFC2.1
#=GS H3NJK7_9LACT/6-136       AC H3NJK7.1
#=GS A1QZL5_BORT9/2-125       AC A1QZL5.1
#=GS B7C7E1_9FIRM/2-124       AC B7C7E1.1
#=GS R5CHF3_9BACT/3-133       AC R5CHF3.1
#=GS R1CDB2_9CLOT/6-136       AC R1CDB2.1
#=GS A0A151E9R5_9EURY/14-144  AC A0A151E9R5.1
#=GS D6D6P4_9BACE/3-132       AC D6D6P4.1
#=GS A0A087ANX5_9BIFI/9-138   AC A0A087ANX5.1
#=GS A0A0G1INZ2_9BACT/3-127   AC A0A0G1INZ2.1
#=GS R6ZUM1_9BACE/3-132       AC R6ZUM1.1
#=GS R6S583_9BACE/3-132       AC R6S583.1
#=GS G8QQG3_SPHPG/3-127       AC G8QQG3.1
#=GS R6D481_9BACE/3-132       AC R6D481.1
#=GS S8FHF3_9BACT/4-133       AC S8FHF3.1
#=GS F3AIT5_9FIRM/19-149      AC F3AIT5.1
#=GS R5PNS6_9BACT/3-103       AC R5PNS6.1
#=GS V7IAG6_9CLOT/5-136       AC V7IAG6.1
#=GS F4GIC0_SPHCD/15-145      AC F4GIC0.1
#=GS M1ZDW3_9FIRM/6-136       AC M1ZDW3.1
#=GS R6SW70_9CLOT/48-174      AC R6SW70.1
#=GS A0A151EHZ6_9EURY/8-136   AC A0A151EHZ6.1
#=GS E0NT44_9BACT/57-186      AC E0NT44.1
#=GS R5CQA2_9BACT/1-127       AC R5CQA2.1
#=GS R6VT86_9FIRM/7-135       AC R6VT86.1
#=GS A0A091FC86_9DELT/5-130   AC A0A091FC86.1
#=GS R5U5H2_9BACE/3-132       AC R5U5H2.1
#=GS R6PGE1_9CLOT/7-137       AC R6PGE1.1
#=GS B8CZZ7_HALOH/7-137       AC B8CZZ7.1
#=GS R7CXR8_9BACE/6-135       AC R7CXR8.1
#=GS Q9X1J4_THEMA/8-136       AC Q9X1J4.1
#=GS Q9X1J4_THEMA/8-136       DR PDB; 1VK9 A; 8-136;
#=GS W4UVZ7_9BACE/3-61        AC W4UVZ7.1
#=GS A0A096AV40_9BACT/4-102   AC A0A096AV40.1
#=GS R5KT16_9BACT/4-134       AC R5KT16.1
#=GS W4LKH7_9BACT/1-94        AC W4LKH7.1
#=GS A0A0G1B0L4_9BACT/1-92    AC A0A0G1B0L4.1
#=GS R7FR51_9FIRM/5-132       AC R7FR51.1
#=GS R5CEM3_9BACE/3-132       AC R5CEM3.1
#=GS R5D450_9FIRM/6-132       AC R5D450.1
#=GS A0A133YZ15_9BACT/4-102   AC A0A133YZ15.1
#=GS U1FP66_TRESO/9-135       AC U1FP66.1
#=GS A0A0L0W8R9_CLOPU/6-136   AC A0A0L0W8R9.1
#=GS R5NH96_9BACT/7-135       AC R5NH96.1
#=GS D1NUB9_9BIFI/6-134       AC D1NUB9.1
#=GS R6YC04_9BACT/8-137       AC R6YC04.1
#=GS C5EJR8_9FIRM/11-143      AC C5EJR8.1
#=GS R6YJD5_9BACE/5-134       AC R6YJD5.1
#=GS U2M7R7_9BACT/3-101       AC U2M7R7.1
#=GS A0A136Q8P9_9FIRM/6-134   AC A0A136Q8P9.1
#=GS R6VPU5_9BACT/4-111       AC R6VPU5.1
#=GS R5Y3F7_9BACE/1-70        AC R5Y3F7.1
#=GS R5V9R4_9BACE/3-132       AC R5V9R4.1
#=GS A6KXX0_BACV8/3-131       AC A6KXX0.1
#=GS R6HW58_9FIRM/6-134       AC R6HW58.1
#=GS A0A090HZ85_9FIRM/7-136   AC A0A090HZ85.1
#=GS F2JJW7_CELLD/6-135       AC F2JJW7.1
#=GS R5S4W4_9FIRM/7-136       AC R5S4W4.1
#=GS R5HDX8_9FIRM/7-135       AC R5HDX8.1
#=GS A0A0M0BX52_9ARCH/9-139   AC A0A0M0BX52.1
#=GS A0A087A776_9BIFI/40-154  AC A0A087A776.1
#=GS R5MH21_9FIRM/6-133       AC R5MH21.1
#=GS A0A139D5C5_9FIRM/1-47    AC A0A139D5C5.1
#=GS F9D2Q4_PREDD/4-102       AC F9D2Q4.1
#=GS W4UWB6_9BACE/1-70        AC W4UWB6.1
#=GS H1BLS1_9FIRM/3-130       AC H1BLS1.1
#=GS A0A151F8T4_9EURY/7-137   AC A0A151F8T4.1
#=GS A0A151BHU2_9ARCH/4-134   AC A0A151BHU2.1
#=GS R6ZE39_9FIRM/201-331     AC R6ZE39.1
#=GS R6UQ07_9FIRM/3-130       AC R6UQ07.1
#=GS D4LDL0_RUMC1/6-133       AC D4LDL0.1
#=GS A8MIM0_ALKOO/6-136       AC A8MIM0.1
#=GS A0A0M0BRL3_9ARCH/8-138   AC A0A0M0BRL3.1
#=GS K1LPZ2_9LACT/5-135       AC K1LPZ2.1
#=GS A0A094JY37_9DELT/5-130   AC A0A094JY37.1
#=GS R7H887_9FIRM/10-138      AC R7H887.1
#=GS R5GFI8_9BACT/3-132       AC R5GFI8.1
#=GS E7GFE5_9FIRM/5-133       AC E7GFE5.1
#=GS A0A0G0XNF3_9BACT/1-92    AC A0A0G0XNF3.1
#=GS Q8A956_BACTN/3-132       AC Q8A956.1
#=GS R5V574_9BACT/8-137       AC R5V574.1
#=GS R6JJ06_9CLOT/6-137       AC R6JJ06.1
#=GS A0A087D361_9BIFI/7-135   AC A0A087D361.1
#=GS R6MIG1_9FIRM/7-136       AC R6MIG1.1
#=GS A0A0P9E1T1_9ARCH/1-116   AC A0A0P9E1T1.1
#=GS R6MT59_9BACE/3-132       AC R6MT59.1
#=GS R5FDS8_9BACT/3-103       AC R5FDS8.1
#=GS R5KEE5_9CLOT/11-140      AC R5KEE5.1
#=GS F3PU95_9BACE/5-134       AC F3PU95.1
#=GS R6PNM4_9FIRM/6-136       AC R6PNM4.1
#=GS A0A0G0QW31_9BACT/6-133   AC A0A0G0QW31.1
#=GS R6GLP2_9FIRM/5-131       AC R6GLP2.1
#=GS E6STQ9_BACT6/3-132       AC E6STQ9.1
#=GS A0A0M0BJX5_9ARCH/4-134   AC A0A0M0BJX5.1
#=GS A0A151BKV1_9ARCH/6-121   AC A0A151BKV1.1
#=GS N6VNU5_9EURY/14-144      AC N6VNU5.1
#=GS R5J3J6_9FIRM/5-135       AC R5J3J6.1
#=GS A0A0M2NQC5_9FIRM/8-137   AC A0A0M2NQC5.1
#=GS R7EL05_9BACE/3-132       AC R7EL05.1
#=GS D4IJU0_9BACT/11-140      AC D4IJU0.1
#=GS D1PTU4_9BACT/4-102       AC D1PTU4.1
#=GS R5AN91_9BACT/4-133       AC R5AN91.1
#=GS O51390_BORBU/4-122       AC O51390.1
#=GS F8N6M7_9BACT/4-101       AC F8N6M7.1
#=GS A0A0G1JZL3_9BACT/7-123   AC A0A0G1JZL3.1
#=GS R6DJY0_9FIRM/1-72        AC R6DJY0.1
#=GS A0A0S8J2Q4_9BACT/9-141   AC A0A0S8J2Q4.1
#=GS R5NP55_9BACT/15-144      AC R5NP55.1
#=GS A9KQT7_CLOPH/10-139      AC A9KQT7.1
#=GS A0A139T590_9FIRM/5-134   AC A0A139T590.1
#=GS W6TIT4_9SPIR/3-96        AC W6TIT4.1
#=GS R6E7N8_9BACT/4-133       AC R6E7N8.1
#=GS R6C3E0_9CLOT/7-135       AC R6C3E0.1
#=GS R7DII0_9PORP/4-133       AC R7DII0.1
#=GS A0A0F0CIW8_9CLOT/5-137   AC A0A0F0CIW8.1
#=GS R7ERT9_9FIRM/6-132       AC R7ERT9.1
#=GS E1RBY4_SPISS/2-118       AC E1RBY4.1
#=GS A0A101HCW7_9FIRM/6-136   AC A0A101HCW7.1
#=GS F0RZM0_SPHGB/7-128       AC F0RZM0.1
#=GS R7KYZ6_9FIRM/1-98        AC R7KYZ6.1
#=GS A0A095Y6X0_9BACT/4-103   AC A0A095Y6X0.1
#=GS U2F271_CLOS4/26-156      AC U2F271.1
#=GS C0EAE6_9FIRM/6-134       AC C0EAE6.1
#=GS D1W0I1_9BACT/6-104       AC D1W0I1.1
#=GS R5VWG9_9FIRM/1-98        AC R5VWG9.1
#=GS R6WND3_9BACT/4-133       AC R6WND3.1
#=GS R5FEN9_9BACT/3-132       AC R5FEN9.1
#=GS E7RMG5_9BACT/6-105       AC E7RMG5.1
#=GS A0A0P9E773_9ARCH/6-136   AC A0A0P9E773.1
#=GS B1C003_9FIRM/6-135       AC B1C003.1
#=GS A0A0G1CV95_9BACT/20-134  AC A0A0G1CV95.1
#=GS A0A087DCQ3_9BIFI/9-141   AC A0A087DCQ3.1
#=GS R6N2P7_9CLOT/5-135       AC R6N2P7.1
I0GII0_CALEA/10-143                 .......................lv--KKSIV.EANLNLAIFM....DN..eLIYS.DTM.....TGISPIF...NF...VKE.N.LNnlkNLKNLYIGDRIV..GKAGAMLISLLK...PKYVYAHILSKSGKEILERYK.IDFEFDTLTNYIINRDKTG.LCPFENAVLNVSDPLTAISIIEETL...................
A0A151EUE4_9EURY/13-143             ........................l-ARKILS.SEDFSIVVVR....DE..kILSH.KKG.....DGIKPIL...KI...IDE.L.GE...EIKGTVIGDRIL..GKASAFLCRYSK...VNGVYTPQATKTAIAILIIGG.IPCQADEMIPFIKNRSGDG.LCPFENMLQNVESPEEAYNILKDN-v..................
A6TMK8_ALKMQ/6-136                  ........................l-AQNELA.EGGYSYVLVK....DE..kVIST.SCD.....KGIQPLM...DI...LLD.E.EK...QMQGSTLADKVI..GKAAAFLCILGE...VKQVYAQVIGDCAKDVLEHHG.IEVEYNRIVPYIMNRDGTD.KCPLEKLVDHVEDPREAYEAIRDFM...................
F0R096_BACSH/3-132                  ........................q-LISLLH.EGGFSCVIAN....HG...ETRT.FSQ.....RGVADLY...EL...YNT.D.PA...FMQGATIADKVV..GKGAAALMIMGG...MAEVYANVVSTPARKLFEQYG.VKLSCGKEVPHIINRQQTG.YCPLETACGEETDLQRLYQIISGFV...................
A0A086ZT33_9BIFI/18-152             aktvllgddslgcvacrtdaatgqt-------.----------....--...LTLT.GTG.....RGVRPLL...QW...LAA.G.QR...-LDGYAAADRVV..GKGAALLYALLG...VSAVYAQTMSEAGLAALRANG.IAAEYGTFVPMILNRAGDG.MCPIERSVAGIDDPAAAERAIRAA-v..................
E2SLS4_9FIRM/4-131                  ........................e-LIKLLK.EESLTCIVEQ....QH...QLYR.EHT.....SGILPIL...HM...LDQ.K.--...HLQGAHLADKVI..GKAAALLMVRGG...VTRVHALILSSHALQIFQRYD.VSITYDELVPYIINRTRTG.MCPMEACVMECDDPALAEQLLRSK-v..................
A0A096BHW2_9CLOT/6-136              ........................m-AKNILF.EKDYSLVVVK....NG..eVIFV.SRE.....RGIKPLL...NI...VLE.K.RD...IVKEASLADKVI..GKAAAMLCIRLG...FTSVFANIISESAVEVLKKSD.IKYEYNTKAQYILNRDKSD.MCPVEKIAQRHENTTKLIEEIKKFL...................
H1XR58_9BACT/3-119                  .....................hsle-------.-------VYK....GN..eLIFA.SDR.....HWLHPLF...ELerfLNA.N.SY...QTAELLVKDKII..GRAAALILVYFG...FKKMQGQTMSLLAREVLDYYK.IDYTFERLIERVA------.-CQTEE-------------------llrtewegktayqlikrri
L1N559_9BACT/4-103                  .........................QLKEKLH.CEQCSLVILH....EG...KMIT.FSG.....HGVRTLY...NI...LSK.Q.PE...VLFESKLAVKAV..GRTAAKNLITGK...VDEVYADFISEPAYNALKDAD.IKVMYGKKVSH--------.-------------------------sef................
R6S1N3_9BACE/4-133                  ........................e-LVSLLH.EGGYSLVLQK....DG...KIHT.FSE.....RGVADLY...RL...RSE.N.PE...LLQGAFLADKVV..GKGAAALMILGG...VAELHADVISEPALSLLAESP.VRVSYGEKVPSIRNRARIG.FCPLETLCKDAKTAAQCLPLIDEFI...................
R5VFC2_9BACT/3-132                  ........................k-IIELLH.AEQCSCVISK....GE...ETRV.FNQ.....KGIADLY...NL...VCR.C.PH...FLEGATVADKVV..GKAAAALMIKGG...IKQLHADVISLSALSLLQKHH.LMTAFGTLVPHIKNRSGMD.WCPLEKRCNKEESVEGIFALIQDFV...................
H3NJK7_9LACT/6-136                  ........................l-AKEVLV.QEVAALVVVR....DQ..eVLYV.RHG.....GGLRPLF...DL...VQE.V.GQ...DLAGSVIADKLT..GQAAARLYQEVG...IVEVFAYTMSAKAREILDQAG.IKYQTDRIVDKIMNRTQDD.LCPMEKIAEGSTSNQEMMAKIQAF-f..................
A1QZL5_BORT9/2-125                  ..............lemisglnptl-------.------KLFK....EH..rILYS.NME.....RGLKPLL...EVdnfINK.Y.IQ...NKEGLEIYDKVV..GKAAAVIIYNIG...LQNVQAGVISQPAKDFLESRG.IRVTFKRLVEKINDKTENL.-------I-----------------eslenpeevykylikr...
B7C7E1_9FIRM/2-124                  ....................nlnkf-------.------IARR....DN..kIFYC.SNE.....IGVKPIL...SK...LNE.N.ID...FYKDADIEDTVV..GKAAACLYVLAK...IKYVYAHTLSETAKIYLENNN.VSFKYDELVKEIRNRTNTD.ICPLEKSVIHIDDPVAAKIALENTI...................
R5CHF3_9BACT/3-133                  ........................s-LIQMLA.DDGCRGVARS....GD..gRLAV.FAH.....SGVADLF...AL...VTD.N.PL...FLDGASVADRVI..GRGAALLLVLGR...VAHVYARVISTGALGVLRDAG.VDVSYGTLVPHIINRAGTG.VCPVEQLTAGTDLPEEAYALIKQFI...................
R1CDB2_9CLOT/6-136                  ........................i-AKSLLK.EEDLAIAIVK....DG..kVLFS.SRE.....KGIKPMY...MA...VSE.L.KE...NLEGSSVADKVI..GKAAAKLCIYGK...VKELNTYLISERAIEVLKEED.IIFTFEKSTPYIKNRDKTD.MCPVEKLSQNIDDTDELLKRISLF-l..................
A0A151E9R5_9EURY/14-144             ........................l-AREVLS.TTDCSIVVIS....YG...KIWKkKKG.....DGIKPFL...EV...IEE.M.GE...DIRSSVIGDRIL..GRASALLCRYIK...AKGVYSPQGTKTGIALLIMGG.VPCQVGKLIPIIKNRAGDG.LCPFEKILKDVISPEEAYTILKTK-v..................
D6D6P4_9BACE/3-132                  ........................e-LINLLH.TGGYSCTIAN....GG...KIRT.FTQ.....RGVADLY...DL...LTQ.E.PE...FLKGALIADKVV..GKGAAALMILGG...IKELYTDIISTKALELFRKSD.VKVDFAQEVDFIWNRDRTG.GCPVETMCSEVESAEEILPLIRDFL...................
A0A087ANX5_9BIFI/9-138              ..................raqrels------A.HDELGCVACR....GG...ETLT.GTG.....RGVKPLL...AW...LAA.G.QR...-LDGFSASDRVI..GKAAAMLYIQLG...AVAVRGHVMSEAGLAMLQSHH.VEAAYDELVPMIRNRANTG.MCPIEQSVRDIDDPAQAEAPIRA--av.................
A0A0G1INZ2_9BACT/3-127              ......................lqy-----FV.DKKLTFVLIK....RN..rVIYK.SKK.....QRLAPLL...FC...LGK.Y.KA...QMRGATVFDKVV..GRAAALLLVYGG...VKKVMAPLISRGALAILKRGG.AEVEYGERVENILNRLGDD.LCSMEKLSQ----------------gknafkfakimk.......
R6ZUM1_9BACE/3-132                  ........................e-LIRLLN.EGGYSCVVRH....GD...ETRT.FSR.....RGVADLY...DL...YCT.D.RD...FLKGAWLTDKVI..GKGAAALMVLGG...VARVWTRVISTPALSLLRNGG.VEVDFAEEVPCIINRTRTG.RCPLETLCDVSDNPAALYPVIEGFV...................
R6S583_9BACE/3-132                  ........................g-LINLLH.TGGYSCTIAN....KG...EIRT.FTQ.....RGVTDIY...DL...LTQ.E.PE...FLKGASIADKVV..GKGAAALMILGD...IKELYTDIISTKALELLQKSD.IKVSFTEKVPFIRNRNHTG.GCPVETMCSEVESAEEILPLIGDFL...................
G8QQG3_SPHPG/3-127                  .......................ay--KQSLV.DNRTLCVFDN....ET...LIFS.DKG.....RWLNPLF...ALetfLDT.Y.QG...SKDHLYVHDTAA..GKAAAVLMVRFG...VKKAHINLISDLAVAYYQRAG.VDVTWEKKVEKL-------.ACMTESLLETMEDSDKMYRLLR---mr.................
R6D481_9BACE/3-132                  ........................e-LINLLH.SGEYSCVIAN....EG...KVRT.FTQ.....RGVADLY...DL...LTQ.E.PD...FLKGALIADKVV..GKGAAALMISGG...IKELYTDIISSKAMDLFRTSD.VKVGFGQEVPFIWNRDRTG.WCPVETMCSEEESAEAILPMIRDFL...................
S8FHF3_9BACT/4-133                  ........................e-LIDMLH.ESNYSCVIRK....GK...VTRT.FVR.....RGIKDLY...EL...IAH.E.KS...FLSGARVADKVV..GKAAAGLMIIGG...VKEVYADVISSPALALFQQYG.LPVSYGKEVDHIVDRTGTD.WCPMERATFSARDAAETYRFITDFL...................
F3AIT5_9FIRM/19-149                 ........................n-AVTILK.EEQKSCVILS....ED..gAVRC.SDA.....IGIKPLM...VE...LRA.D.RR...AFQGSVIADKVV..GKAAALLAVLGE...VQAVFGRVMSEGAVSIFEKHQ.IPYQFETLVPYIENRTKDG.MCPMEETVQLVENPEEAFEALEKTI...................
R5PNS6_9BACT/3-103                  ........................h-LIDTLH.SGQDSLVILH....EG...RQRS.FGG.....QGLRKLY...NI...AVQ.E.PE...LLLGAKLADKAV..GRTAARVMAEGG...VAEIYADYISDQAYDLLIDAN.IKVRYGKKVDH--------.-------------------------atfl...............
V7IAG6_9CLOT/5-136                  ........................l-AKELLE.THEAACIILR....DG..eIIFT.HVG.....IGVKPLL...AF...MEK.P.ID..eRSGNLTLVDKVI..GKAALLMAVKLG...IRNIYTPLVSEEALDAAKVHG.VRIDALETVPYIINRTNDG.KCPLEQSVTGVYDPEEAFVKIKQAI...................
F4GIC0_SPHCD/15-145                 ........................e-ALHLIE.TGTISCVVIQ....DD..aIVHK.ADG.....RGVSPLL...KL...YDT.A.PE...KLKDAVVIDKII..GKAAAMILVAGG...VRKAYGQIMSAAAKKYLDAHS.IETEYGRYVDVIENRYKTG.MCPIEQSVIDSEDPLEGLEKIRKTV...................
M1ZDW3_9FIRM/6-136                  ........................i-AKKYLE.EENLAIAVVK....DG..nLIFK.SHD.....KGIKPMY...TL...ATQ.M.VE...MTKGSSIADKVI..GRGAAMLCDSLY...VKEVYGKLISDNAIEVLKKSG.IIFSYGNICDYIKNRDGTD.ICPIEKIALQSENSEVLLSKIKGF-f..................
R6SW70_9CLOT/48-174                 ..................rareclq-------.-AGKTLVLCK....GE...TVYM.SER.....QGIGQML...EY...LEE.K.VD...-LRGFCAADKVI..GRAAAMLFASAG...VREVWGDVISRAALPVLEAYD.ISYRYGRLADRIINRRGDG.LCPMEEAILAANTPREAYNILR---gr.................
A0A151EHZ6_9EURY/8-136              ........................y-AQEEFE.KRESAFVIVR....NK..eVLAE.SKE.....KGVAPFF...DV...VHS.I.N-...-VKGASLADKIV..GKAVAFLCVYAG...ITSVYTPVASEPAVFVLRENR.IYYEADKMVPMILNRDKND.QCPIEQTISACTTPEEAYSLLRKK-f..................
E0NT44_9BACT/57-186                 ........................d-LMETLQ.AGNYSMVVLH....DG...KIRK.YEG.....RGIDELY...RL...LRE.R.PE...RLYEAKLAYKVL..DKASAGLMVIGG...VNDIYAGVMSKQAIPLLDEAG.VRYMFDKLVDHITGADGED.WNDWERICAPHRNAEEVLIAVKQS-m..................
R5CQA2_9BACT/1-127                  ........................m-----LG.HDGCRGVMRS....PG..gKTIV.FRR.....RGVADLF...DA...VTS.H.PD...LTQGASVADKVI..GLGAAFLLVKGG...VAEVYAEVISRPAVSKLQDAG.ISLSYGKTVDHIINREGTG.ICPVEQLTAEAKSPDEAWKLIKEFI...................
R6VT86_9FIRM/7-135                  ........................k-AKNELE.KQRCTCVFAN....GE...NVTI.CSE.....HGLKPLL...TR...LGD.S.KL...-QKGFSAADKVV..GKAPAFLYVLLG...ASEVYAPVMSEGGKRVLEQYG.IGAFCDTLTGEIRNSDNTD.ICPMEKAVSCAGSPDEALECISAKI...................
A0A091FC86_9DELT/5-130              ......................dft-------.--RYSLALVQ....GD..kIIFS.SQR.....RGLRPLW...DC...LQN.Y.RQ...TKERFILHDKVI..GLAAERLVVYSG..iIAEIQTLLISQPAKKFLYENN.IKVEAEKTVANILTQDMRS.ICHGEIIALNIADPDEFSQKI----mmmf...............
R5U5H2_9BACE/3-132                  ........................e-LINLLH.TGGYSCVIAN....EG...KIRT.FTQ.....RGVADLY...DL...LTR.E.PE...FLKGALIADKVV..GKGAAALMILGG...IKELYTDVVSSNAMDLFRTSD.VKVDFVQEVPFIWNRDHTG.WCPVETMCSEEESAEAILQLIRGFL...................
R6PGE1_9CLOT/7-137                  ........................q-AVALLK.EKQVSCVIWI....EG..kEPIL.SDE.....IGIKPLM...KE...LRK.E.RH...AFEHGVIADKVI..GKAAALMAILGG...AKAVYGQVLSESAEKILQIYG.IEYAYEEKVPYIENRTKTG.QCPLEESVVSVDDPEKAFEVLEETI...................
B8CZZ7_HALOH/7-137                  ........................i-ARKILE.REERTLVIVK....EG..kVLFV.SDD.....NGIKPIY...MA...VTD.L.AH...ELEDASLADRVI..GRAAALLCVAYG...IKEIYARLISKEAIRLLEQNG.VSYNYRERTPFIKNREGTG.MCPVERMSLDVDDGKHLVKRIEEFL...................
R7CXR8_9BACE/6-135                  ........................t-LVRRLH.EGGCTLVVAQ....GD...DVRL.FTR.....RGVVDLM...DL...TDN.D.PA...FLHGALVADKVV..GKGAAALLVKGG...VTALHTDLISRPALDLLSRAG.IDVTYDTLTDHIVNRDGTD.WCPVERLCRPLDNIDEMVDAIRAFI...................
Q9X1J4_THEMA/8-136                  ........................s-ALKIFE.KKDLSLLAYS....GR...SIFE.SKD.....SGLKPVV...EL...FKR.F.DN...-LEGSLVIDKMV..GKAAASFLLKMK...PDHIHAKVISKPALKLMNEYG.QSFSYDEKIPFVLGKDGKS.MCPFEKLVLEMDDPEEIIRIVL---skf................
#=GR Q9X1J4_THEMA/8-136       SS    ........................H-HHHHHH.HTT-SEEEES....SS...EEEE.E--.....STTHHHH...HH...HHH.-.S-...--TT-EEEEEEE..-HHHHHHHHHH-...-SEEEEEEEEHHHHHHHHHTT.--EEEEEEESS-B-SSSSS.B-HHHHHHHT---HHHHHHHHH---TT-................
W4UVZ7_9BACE/3-61                   ........................e-IIDILH.EGNYSCVIRN....ND...QIYT.FTQ.....RGVADLY...DL...IKT.Q.PD...LLKGAFLADKVV..GKGAA-------...---------------------.-------------------.-------------------------p..................
A0A096AV40_9BACT/4-102              ........................e-LIDKLH.IEHCSLVLLH....EG...NIRT.FEG.....KGVRMLY...NL...LND.E.PE...SLFKSKVAVKAV..GKTAAKAMVDGG...VTEIYADVISEEAHYRLKDAG.IKVDYEKKVNH--------.-------------------------qr.................
R5KT16_9BACT/4-134                  ........................e-LRNMLV.DDGCRGVARS....VQ..gEIRT.FER.....RGVADLF...SL...VTD.E.PD...FLRGASVADKII..GRGAALLLVKGG...AAEVYAQVISSGALEVLIQAG.IEVEYGQLVANIINRTGTD.ICPVEKLTADTASPDKAYVMIKQFL...................
W4LKH7_9BACT/1-94                   .................mnestltm-------.--------LR....DG..vPIFT.SYG.....NWLHPLF...ELedyLAE.H.PV...QPEHLVLQDKII..GKAAALLINRLE...FRTVKVGILSRPGEVVLKSHG.IDYTYGQIV----------.-------------------------tw.................
A0A0G1B0L4_9BACT/1-92               .....................mifc-------.----------....--...----.---.....-------...--...FKN.Y.RQ...QMRGAMVFDKVV..GRAAALILAAAG...VARVEAPLICAEAIKILRAKK.IEVGYIKKVKNILNRTGND.LCPMEKLSA----------------gktikefkk..........
R7FR51_9FIRM/5-132                  .................elakenls-------.--GHTLALCK....DG...NIIT.SDK.....RGVAPMV...DF...LRE.G.HD...-LSGYSAADKVI..GKSAAMLFIKAG...VKNIFAGVISECAEKLLLAYD.VEVSYGEKTERIMNRDKTG.LCPMESTVFDIDDIDVGVAAIERKL...................
R5CEM3_9BACE/3-132                  ........................e-LIDMLH.AGGYSCVIAN....GD...RIRT.FTR.....RGVADLY...DL...LVQ.E.PE...FLHGAFVADKVI..GKAAASLMVLGG...VRQVYTRTISQPALRLLQEAG.VTVSCDEIVDHIINRDHTG.WCPLEQASRDLQSAKEIFPVIEKFI...................
R5D450_9FIRM/6-132                  ........................r-AKEALT.TIGCTCALCR....DE...EVRT.TQL.....RGVAPLL...SW...LEE.G.--...-LSGWSVADRVV..GAGAAWLYTLLH...PAMVYAPVMSRRATAILTQYG.VPYTCDEVAESILNRTGTG.LCPMEEATANAADPQQALAAIRQKV...................
A0A133YZ15_9BACT/4-102              ........................d-VIDTLH.TEQCSLAILH....EG...NIRT.FDG.....HGVRRLY...NI...IND.E.PE...LFFKAKLAVKAV..GRSAARMMVEGG...VTEVHAEVMSQQAYDVLHDAG.IAISFDKKVDH--------.-------------------------at.................
U1FP66_TRESO/9-135                  ...........lpehttlcvydgdt-------.----------....--...LIFS.NGG.....KWLMPLFaleDF...FKT.Y.DG...SRSDLCAHDTAV..GKAACVLMIRMG...IKKIHANIASALAIDYVAELNrVRGGHDPIELSYDTSVRRL.LCATEDRLETMHDSDEMYTHL----rf.................
A0A0L0W8R9_CLOPU/6-136              ........................l-AKDTLE.KENLSLVIVK....DG..kILFR.SAD.....KGIKPIY...NA...VLQ.S.EK...NFKGSSIADKVT..GKAAALLCKCLD...IKRLFTEIISEGAINVLENSH.IIFTYDKAIPYIKNRDMTD.VCPIEKIAQYIDEPEVLISKISEFL...................
R5NH96_9BACT/7-135                  ........................d-LIDLLH.ERKCSCVLRN....G-...EIYT.FER.....RGVEDLY...DL...LRE.Q.PG...LLLGADVADKVV..GKGAAALMVLGR...VRRVYADVLSEPAYGLLFQTG.ISVSYGRLVSAIRNRAGNG.WCPVETLCRDKETAEECLPLIAGFV...................
D1NUB9_9BIFI/6-134                  .......................ak--QTLLE.NDSLRFAAVK....DC...EIIT.DTD.....YSLRPLL...KL...LDA.H.RT...-LAGFTAADRVI..GKGGALLYVLLG...VRTVYAPIMSRDALETLERHG.INADYEELVPTISNYAETG.ICPIEDAVSNIDDPLDAESAIR---pvv................
R6YC04_9BACT/8-137                  ........................q-AIELLF.AEKCSCVIRN....GD...SMRI.FRE.....RGVADLF...RL...LHE.E.PQ...LLRGAFIADKVV..GKGAAALMVLGG...VEGLFADVVSRPALELLAGAG.IAVEYTVVVPNIVNRAGTG.TCPVEQLCAGAASAAECLPLIEGFM...................
C5EJR8_9FIRM/11-143                 .....................llqk----VST.REALAILTDD....SG..sIIWE.TDK.....SPVAGMY...HA...YYE.G.GL...TGTGNLVL--YA..NQAGIAMGIMAEqipIRECHAARVSEGGLRILNERG.IAVTYEEVIPLVKSSKDDSkVCPVEQFLFEHGDRKDQWEFLEE--ry.................
R6YJD5_9BACE/5-134                  ........................e-MIERLH.TGNYACVIRN....GN...EERV.FYQ.....RGVADLY...DL...LKN.Q.PD...FLNHAQVADKVI..GKGAAALMALGK...VAEVYTDVISRPARALLERES.IPVTYVTEAPYIRNRAQTG.QCPVETLCSETDDLQEMLEKISGFL...................
U2M7R7_9BACT/3-101                  ........................e-LKDKLH.SEQCSLVVLH....EG...NIRT.FDG.....RGVRTLY...DL...MTN.E.PE...VLLDAKLADKAV..GRTAARMMAEGG...VCEVYADIISEQALSALEDAG.IRVTYGNKVSH--------.-------------------------qd.................
A0A136Q8P9_9FIRM/6-134              ........................r-AKALLQ.TEDCSCVLVK....GD...IIYT.SRK.....AGIAPLV...EF...LSS.G.AG...-LNGFSAADKIV..GKAAALLFALAG...AREIYAPVMSGSALPVLRQNG.IAFSCDTLTPSIENRAGTG.PCPMEKAVAEIDDPAQAFTAIKTA-m..................
R6VPU5_9BACT/4-111                  ........................q-LIDRLH.ADHLSLVILH....EG...RVAT.YEG.....HGVRALY...HI...LDN.E.PE...LLLDAKVAIAAA..GHTAAQAMKEGG...VVEVYADYISEQAYDTLHAAG.IKVTAVHKVSH--------.-------------------------hdflkiwermg........
R5Y3F7_9BACE/1-70                   .........................-------.----------....--...----.---.....-------...--...---.-.--...------------..-------MAIGG...VKKVHTGVISESAYDLLVRSG.IEISFDKKVAYIINRTQTD.RCPLEKLCADASTPQECIPLIDAFI...................
R5V9R4_9BACE/3-132                  ........................e-LIRLLN.EGNYSCVVRQ....GE...ETRT.FSR.....RGVADLY...DL...YAT.D.RA...FLKGAWLADKVI..GKGAAALMVLGG...VSRVWTRVVSTPALDLLRKGG.VEVAYAKEVPCIINRTRTG.RCPLETLCDVSDNPVELYPVIEDFV...................
A6KXX0_BACV8/3-131                  ........................e-LIRLLH.EGGYSCVIRK....E-...EIRT.FTQ.....RGVADLY...DL...LNQ.H.PA...FLHGAQVADKVV..GKAAAALMVLGG...VREVYTDIISEPALAVLHKAN.IRVECVQIVSRIWNRNRTG.WCPLETLCYELESPEAMYPVIQNFV...................
R6HW58_9FIRM/6-134                  ........................h-AKQLLT.GEGYTCVICR....GD...DIHT.SEK.....RGVAPLI...EL...LDS.N.ID...-VRGYSAADKTV..GKAAAMLFVLLG...VGEIYAVVMSRSAKKILDGHG.IKYSCGEEVEYIINRKKDD.MCPMEKAVMDIDDPAEASTKIKETI...................
A0A090HZ85_9FIRM/7-136              ........................i-AKNYLI.DKDQTLVIVK....NG..nVLFK.SNE.....TGVKVLV...EI...FKS.Q.PN...ILEKASVADTIT..GRAAAIIYSHGN...IKELYTNLISKNAEEVLDKKS.ISYIYKNKVDNIMNRTKTD.LCPIEKIAKKSSTIDELIYKIEDF-...................
F2JJW7_CELLD/6-135                  ........................r-AKKLLR.ETDSTCIALI....GE...ESYL.SKE.....RGISPIL...NQ...LEK.N.EQ...FFKGAIVADKVV..GKSAAMLYKKAQ...IHSLYASIISEHALRALKDTE.IIVTYEKVVPYIINRQGDG.MCPMEASVLEIEEVNEAYEALRNKM...................
R5S4W4_9FIRM/7-136                  ........................q-AKALLEnNEEYTCAACR....AG...ESFA.SEE.....HGVRPLM...RW...LNE.G.TD...-LSGASAADRIV..GKAAAFLYVLLG...VRTVYAPLMSVPARETLCAHG.IEAIADAVVPAIRNRTDTG.FCPMESAVWDISDPHEAKAALERKI...................
R5HDX8_9FIRM/7-135                  ........................k-AKETFA.QGNYTCVWCR....DN...ELLT.SKE.....AGLRPLL...TR...IRE.G.KD...-LNGFYAADKIV..GRAAAFLYVKLG...AAGVYAPVMSRGAKELLAEYN.IPAEADELTENIRNRQNTG.LCPMECAVSSCGSPEAAYAAILEA-i..................
A0A0M0BX52_9ARCH/9-139              ........................i-AKNRLQ.SKELTLVIVK....NK..eLIFE.TKK.....TGLIGFI...EA...IEM.N.GI...LLKNSSVADKVV..GKAIAFLCVYSK...VVSVYAEVVSVEAKKLLEKNK.IMLKWSMIVKEILDTKKNT.TCPFEMKAKNMDDPILFY-------felknsi............
A0A087A776_9BIFI/40-154             ......................hge-------.----------....SD...EILT.GFG.....RGVRPLL...QW...LAE.G.RS...-LVGYSAADRVV..GKGAALLYARLG...VVAVYAETMSEAGLATLRTQG.IAASYGTLVPVILNRTRTG.ICPIERSVASISDPLAAEPAIRA--av.................
R5MH21_9FIRM/6-133                  .......................ka--KERL-.KNGASLVLYD....GK...EFIE.ENG.....KGLSPLL...KL...LSE.R.ND...-LSRFCAADKII..GKAAAMLFSLLK...IKSVYGEVLSRKAIPILEKYG.INYSFGTVTDSIKNRYGTG.ICPMEQTVEGIDDADTALKAIKEKI...................
A0A139D5C5_9FIRM/1-47               ...............mqvlekakkf-------.----------....--...----.---.....-------...--...---.-.--...-----------IetGKAAAVITTLAG...VEKVYGEVMSEAALDYLKE--.-------------------.-------------------------lkn................
F9D2Q4_PREDD/4-102                  ........................e-LIDTLH.IEQCSLVILH....EG...NIRT.FNG.....HGVRRLY...NL...INE.E.PE...LFLDAKLAVKAV..GRSAARMMVDGG...VAEVYADIISQQAFDVLRDAG.IVVKCEKKVDH--------.-------------------------qt.................
W4UWB6_9BACE/1-70                   .........................-------.----------....--...----.---.....-------...--...---.-.--...------------..-------MILGG...VTEIYTDIISLSALMLLREAG.VQADYGQVVPFIQNRDQTG.WCPVEAMCYNETSAEAIFPLIEGFI...................
H1BLS1_9FIRM/3-130                  ........................s-LMKILK.EEHLSCIVSQ....NN...HIYK.EKA.....DGIRPIL...TL...LDK.G.--...VLKDAQIADKVI..GKAAAMMLVFGG...IKEVHAGVISEPALHFLQAHH.ILVHYELLVPNIINRKKDG.ICPMETCVLHIDDMELAYHKL----vhll...............
A0A151F8T4_9EURY/7-137              ........................s-AKREFK.RTKAAFVIVK....DE..kVVAR.SAE.....KGVAPFF...FA...ANG.L.GE...QVKNASLADKIV..GKAVALLTVNSQ...MISVYTPLISDPAVKVLNDYN.IYWEADQIVAMILNRNKDD.QCPIEKMVTACDTPEEAFSILKRK-f..................
A0A151BHU2_9ARCH/4-134              ......................hlr----ELR.ERGLSLLIYD....GEggrVLYS.SEE.....GGLKPLV...EA...VEAvG.LE...RLRGCIVVDRVV..GRAAALVAVYMG...ASEVHAVLMSWGAEGVLRRFG.VPYSFLVETDYIRGRDG-G.PCPFEREVSGVEDPGEAYRRVK---il.................
R6ZE39_9FIRM/201-331                ........................k-AKAMIA.SEEASFVVIK....NN..qIIYQ.DKG.....NGVKPIM...KV...LDT.D.RE...LLQGAVIVDKII..GKAAAMMLSMGG...AVSVYGSLMSQAAEEYLEKKG.IEHSYGRCIQVISNRTGDG.LCPLERAVADIDDEAQAYEKLKQTI...................
R6UQ07_9FIRM/3-130                  ........................e-LIRILK.AEELTCVVLQ....KQ...RLYK.EHA.....NGILPIL...HL...LDQ.G.--...HLQGAQLVDKVI..GKAAALLMVRGD...VHQVHACVISSHALEIFQLYN.IPVTYDEQVPYIINRTKTG.MCPMEACVMDVNDPAAAQRLLNAK-v..................
D4LDL0_RUMC1/6-133                  ........................r-ARTLLT.EGCYTCVLCR....VD...VCYT.SHS.....KGISPML...DW...IGA.G.VE...-LRGFCAADTIV..GKAVAMLFVHAG...VCAVYGRVMSTAGRDYLTAHG.VACSYDTLTEQIVNRTGDG.VCPMEQTVAQLEDPQVAYAALRR--k..................
A8MIM0_ALKOO/6-136                  .......................la--ANKLM.EGQFSCVLVK....DG..eVLMT.SKD.....RGIRPII...KM...LME.D.QN...SLKDRVLADKII..GKAAALLVVFGQ...VEYLYAHVISDCAKNILEKNN.IVVNYNHIVPYIMNEDGTD.KCMMEKMVEDIEEPAEAFALFKDF-f..................
A0A0M0BRL3_9ARCH/8-138              ......................yle----KLE.KLSLNLQIHR....GG..eAIFS.SAG.....SGIAPLI...EA...IDSiG.RA...GLRGSIVADKIV..GRAAALMAAYME...ASEVHAALISAGAKEVLRGHG.IGFRFSRETRAILSRDGAD.LCPFERLVLDVRDPSEAYKRIKAKL...................
K1LPZ2_9LACT/5-135                  ........................s-VIKLLH.DEDYALVIEH....QE...QVYP.FEG.....RGIRPLY...EV...YRH.Q.KA...LLNQSLVADKVS..GKAHAMLCVAGG...AKAVYADLMSADATEIYQSNG.IHYEYGQSVPHILNRDRSD.LCPIEQLAGDL--------------tpdcveslciriesf....
A0A094JY37_9DELT/5-130              ......................dft-------.--RYSLALVQ....GD..kIIFS.SQR.....RGLRPLW...DC...LQN.Y.RQ...TKERFILHDKVI..GFAAARLVVYSG..iIAEIQTLLISQPAKKFLYENN.IKVEAEKTVANILTQDMRS.ICHGEIIALNIADPDEFSQKI----mmmf...............
R7H887_9FIRM/10-138                 ........................r-AKELLK.EKHYTCVLCK....DA...QCVT.SKE.....HGVKPLL...AF...LNS.G.ES...-YADFSAADQIV..GQAAAHLYLLIG...VSAVYADVISKGTIQLLTEHH.IPVEHGTVVDQIRNRAGND.ICPMEKAVTGIIDSQLAVQKIQETI...................
R5GFI8_9BACT/3-132                  ........................a-LIDRLH.RQKCSCVIAN....GD...DVRM.FHQ.....RGVADLY...DL...LRG.E.PA...FLQGARVADKVV..GKGAAALMVAGG...VAELYADTLSRRAMDLLETHG.VSVDCAQVVSGIRNRAGTG.WCPVETLCASLTDIGEMVEAIGRFL...................
E7GFE5_9FIRM/5-133                  ........................l-LQEKLN.KENYTLIADK....NG...EYYT.SYS.....RGIAPIL...DP...MKD.D.QS...FFKGAIVVDKVI..GKATAMLLILSG...VEFIYAYVLSQKAMEILEQYH.VPFEYRKLVDYIENRDQTG.MCPMEATVYDINDLNEAFEAL----ilk................
A0A0G0XNF3_9BACT/1-92               .....................mifc-------.----------....--...----.---.....-------...--...FKN.Y.RQ...QMRGAMVFDKVV..GRAAALILAAAG...VARVEAPLICAEAIKILRAKK.IEVGYIKKVKNILNRTGND.LCPMEKLSA----------------gktikefkk..........
Q8A956_BACTN/3-132                  ........................e-LINLLH.SGGYSCVIAN....GD...NIRT.FTQ.....RGVADLY...DL...LTQ.E.PD...FLKGASIADKVV..GKGAAALMILGG...IRELHTDIISSKALDLLRSSD.IKVHFVQEVPFIWNRDHTG.WCPVETMCSEEESAEAILPLIRDFL...................
R5V574_9BACT/8-137                  .....................qtvg----LLF.AEKCSCVVRN....GD...EVRI.FRE.....RGVKDLY...RL...LRE.E.PQ...LLDGAFVADKVV..GKGAAALMILGG...VEELFADVVSRAALDLFAAAG.KAVAYTVAVPHIINRADDG.ICPVERLCAEAQTAGECLTL-----negli..............
R6JJ06_9CLOT/6-137                  ........................f--QKVLA.KTALAILTDD....SD..nIIWE.TDK.....SPVSGMY...RA...YFK.N.KF...----SESKDMILyaSQAGIAMGIMAGqipIRECHAVKVSEGGLRLLKEEG.VKSAYEEIIPLIKSSKDDNiICPIEQFLYEHEERQEQWRFLEA--rf.................
A0A087D361_9BIFI/7-135              .....................akaa----LFA.DDAFGCVACR....SD...ETLN.GSG.....HGVRPLL...QW...LSS.G.RS...-LAGFSAADRVV..GKAAALLYARLG...VEAVYARIMSEEGLAMLQLYG.IASSYEQLVPMILNRSGDG.MCPIERSVQAIVDPVAAVPAIRAA-v..................
R6MIG1_9FIRM/7-136                  ........................s-AKEQLH.NNNFSIVIVG....EN...DVYT.STK.....HGVAPLL...EI...LDG.G.DD...IIKNSFAADKVV..GKAAALLMVKGG...VKEVYADIISSHALDVFEKYK.VKAYYDNLVEYIINRDKTG.MCPMEKAVLEVDEPNTAYDVLKKKI...................
A0A0P9E1T1_9ARCH/1-116              .......................mk-------.---------R....GK...VILE.TES.....HGIIGPL...QA...IDR.L.GE...ELMESSVADKIV..GRAVALLCAYSK...AFSVFAVTISKEGMRVLEDNN.IFYEIENCVPNILDYKRAD.VCPFEKLAAGFANPREAYEKLKSFI...................
R6MT59_9BACE/3-132                  ........................e-LIEKLH.TGGYSCVIEK....EG...KIRT.FTR.....RGVADLY...DL...YEN.E.KA...FMQGARIADKVI..GKGAAALIALGK...MKEVYTDVISTSALSVLREAG.IPVRYAEETPFIINRDKTG.RCPLETACKDLNTPEEMYPAIKAFV...................
R5FDS8_9BACT/3-103                  ........................e-LINTLQ.EENCQLVVLH....EG...NITT.FEG.....RGVRHLY...NI...MQE.Q.PE...LLLGAKLAVKAV..GRSAAQMMKKGG...VVEVWAEYMSQQAYDLLTDTG.IKVSYDHKVDH--------.-------------------------nkfl...............
R5KEE5_9CLOT/11-140                 ....................qakdl----LLA.NETYTCVLKK....ED...DCQF.SQE.....HGVLPLM...QW...IDA.G.KH...-FKGYAAADRIV..GSAAAYLYILLD...VREVYAQVMSQGAIEILSQHG.ITAIHDVTTATIRNRANTG.SCPMELAVQNSRTPEEAYDAIRRKL...................
F3PU95_9BACE/5-134                  ........................t-IIDILH.TGQYSCVIKN....RT...EIRT.FTQ.....RGVADLY...DL...YQS.D.PA...FMKGASIADKVI..GKGAAALMVLGG...MRTVYADIISTPALTLLRHEG.IETTFAKEVPHIINRDKTG.WCPLETACDKLESVTEMYPVIQNFI...................
R6PNM4_9FIRM/6-136                  .........................QAKKALE.AEGVTFAAVS....PS..gEQKT.SQK.....KGIAPMM...EI...LAE.C.PE...FLQGAAVADQVI..GKAAAFLLRKGG...AKYLYAKIISEHALETLKDSG.IAVSYGTKVPYIINRKKDG.MCPMEQTVLSVTDVEEAYGKLQEKL...................
A0A0G0QW31_9BACT/6-133              .....................nley-----FF.EKSWSFVLMK....NG..kIVFK.SKA.....QHLKPLI...FC...IKR.H.KK...EMRGAVVFDKII..GQAAAIFLVYAK...VKEVWTPTISRSGKACLEKHN.VKIDYKNLVSCIKNRKGDD.LCPMEKMSRKMTKKEFIEKKL----en.................
R6GLP2_9FIRM/5-131                  ...................kaksll-------.-KDYTSVVFK....DD...TVYY.SEH.....RGVKPLM...IL...FDN.G.VD...-VSCGEAADRVI..GRGAAYLYVALK...IKHVSAYVISKPAIEVLERYG.IEFDSDEVADNIRNHTNTG.ICPMEEVTENATCPQEAIKLMKA--rl.................
E6STQ9_BACT6/3-132                  ........................g-IINMLH.AGGYSCVIKK....RD...ELRT.FTQ.....RGVSDLY...DL...YQT.D.PV...FMKGAAIADKII..GKGAAALMVLGG...IEKVYADIISTPALALLCDAG.IETSFAQEVPHIINRDKTG.WCPLETACSQLKYATEMYLVIQDFI...................
A0A0M0BJX5_9ARCH/4-134              .......................yl---QRLK.LEGLSLLILK....GG..tPLFT.SDE.....EGLRPLF...DA...ITS.SgLS...VLEDTVVVDKIV..GKAAALLISYFR...AKEAHCIVLSMKAKEVLDRHG.IQHYWEELTPTILNRTGTG.ICPFEQAVMDVDDPREGYERVGS--tl.................
A0A151BKV1_9ARCH/6-121              ........................e-AKRILR.DQNLSLVIVK....DG..vLLLS.LDS.....RGIDGLL...QA...IRR.L.GG...RLSGASVADKIV..GKAAALLLAYSK...IARAYASTISRSGLATLSRYG.IPVEYDSLVPKILDKDRRG.VCPFEKLA-----------------sn.................
N6VNU5_9EURY/14-144                 ........................l-AREVLK.KTDCSIVVVK....DG..dVLIK.KKG.....DGIRPIL...EV...IEE.L.KE...EIQGSIVGDRIL..GKASALLCRYSK...IKGVYSPQATKTAIAVLIIAG.IPSQIDEMIPYIKNRGGSD.VCPFEKMLSDIDSPEEAYEILKEKI...................
R5J3J6_9FIRM/5-135                  .......................nl--PALFE.NGAYTLVVQK....DG..vTVHK.DFG.....RGVGPAL...RV...FDA.Q.PE...LLKGALVCDTIV..GKAAAAIYLLGG...ASGVYAETMSAAAADFLIANG.VDCACETKTEKLLNRQGTG.LCPFEQAVLELERPEDCLPVVRAT-l..................
A0A0M2NQC5_9FIRM/8-137              ........................e-AKRIIL.QDKAACVVAY....QK..eILYL.GQG.....KGIFPLM...EY...FER.E.EL...HRSGIAIFDKVI..GKAAATFVVSLK...PKYVFAKMISEAGYDLLRRNG.IRTEFETKVPMIMNRDKSG.MCMLEEKVQHIDAVDECVAVLQD--w..................
R7EL05_9BACE/3-132                  ........................s-IIDILH.KGGYSCVMKN....RE...EVRT.FTQ.....RGVADLY...DL...YQA.D.SA...FMKGAAIADKVI..GKGAAALMVLGG...FKTVYADIISTPALALLCEAG.IETTFAQEVPHIINRDKTG.WCPLETACIELNTVEEMYPVIQNFI...................
D4IJU0_9BACT/11-140                 ........................q-AIDLLF.AERCSCVVRN....GD...TIRI.FRE.....RGVRDLW...RL...LHE.E.PE...LLDGAFVADKVV..GKGAAALMAAGR...VRELFADVVSHAALELLNGAG.IPVSYTVAVPHIINRAGDG.ICPVERLCAGARTAAECLPLIEGFL...................
D1PTU4_9BACT/4-102                  ........................e-LIDTLH.TEQCSLVVLH....EG...NITT.YDG.....HGVRRLY...NI...IND.E.PE...LFLEAKLAVKAV..GRSAARMMAEGG...VAEVYADVISQQAYDVLNDAG.IVVKYEKKVDH--------.-------------------------st.................
R5AN91_9BACT/4-133                  ........................s-LVDLLH.KGNHTLVVAN....GD...DVRT.FGR.....RGVADLF...EL...LTS.N.PE...FLRGASVADKVV..GKGAAAMMILGG...IGRLHTDIISDAAIELFRDSG.VEISYDTRVPFIANRDHSG.RCPVETLCEPCATAAECLPLIESFI...................
O51390_BORBU/4-122                  .................glnptlrl-------.--------FK....DH..kILYS.NME.....RGLKPLL...EVdnfINK.Y.IQ...NKEGLEIYDKVV..GKAAAVIIYNIG...LQNVQAGVVSQPAKDFLESRG.IKVAYKKLVEKINDRAESL.-------------------------ieslenpeevykymikr..
F8N6M7_9BACT/4-101                  ........................e-LIDTLC.DEQHTLVVLH....EG...RIRT.FDG.....QGVRHLY...NM...INE.E.PE...LLYDAKVAVKAV..GRSAAAMMVEGG...VIEVYAEYISQQAYDTLKEAG.IKVSFEKKLN---------.-------------------------hq.................
A0A0G1JZL3_9BACT/7-123              ...................lelwlg-------.----------....NK...TIFR.SKK.....SGVRGLL...DF...INE.R.GG...GQEGIVIFDKIV..GQAVAFLAAYLG...AKEVYGGTGSELAAKALEKYK.IKFHFQKTIPNILNRDKTD.LCPMEKLSIDK-APEEFYKC-----linr...............
R6DJY0_9FIRM/1-72                   .........................-------.----------....--...----.---.....-------...--...---.-.--...------------..-----MLLEKYG...ASEIYAQVTSKYAVAYLENKS.VKLTYEKKTDHIINRLGTD.MCPVEEAVLNVNDADDGENLIKDTI...................
A0A0S8J2Q4_9BACT/9-141              .........lndfargawdlvilld-------.----------....-E..vIIYH.SDKedlsgQGIKPVV...DF...IRK.F.GT...SLKNVVIYDKIV..GQAVALLFVFLK...VKKVYGVLGSEKAEKVLKKYQ.IPYLFLKIVPYISNRDKTG.PCPFEI-KAERKTPEEFWKMVSE--ec.................
R5NP55_9BACT/15-144                 .......................sl--IGYLF.AEKCSCVIRN....GK...DIRV.FRE.....RGVKDLY...RL...LKE.E.PE...FLKGAFVADKVV..GKAAAALMILGG...VKELFAGVASFPALELCRKTG.LRVGCIHEVSYIVNRMQTG.WCPLEIRCKNLETPEECRIKIEEFI...................
A9KQT7_CLOPH/10-139                 ........................k-VTEKLK.EGGYSFVLYK....DG...EWST.SEK.....RGIAPIM...EL...LKE.N.KE...LLRGAYVADKVI..GKAAALLLIEGG...ISYLHAEIISEHAIEVLQNSN.IEYEYQELVPYIVNRSGDG.MCPMEETVLDVTDTKIAFELLQEKI...................
A0A139T590_9FIRM/5-134              ........................s-LQEKLN.NEDLTLVAQI....QD...TIYT.SQL.....KGIAPLI...NP...MKE.N.QL...FFKDAIVVDRVI..GKAAAMLLALSQ...VQYIYAYVLSRKAREILDAYK.IDYDYEKLADYIVNRDHTG.MCPMEKTVYDMTDLNEALSALI---qkq................
W6TIT4_9SPIR/3-96                   .................sglnptlr-------.-------LFK....EH..rILYS.NME.....RGLKPLL...EVdnfINK.Y.IQ...NKEGLEIYDKIV..GKAAAVIIYNIG...LQNVQAGVISQPAKDFLESRG.IRVSFKK------------.-------------------------agr................
R6E7N8_9BACT/4-133                  ........................d-LVRLLR.EGGYSCVLQK....DG...EVRT.FHR.....RGVIDLY...TL...LVE.D.PG...YMRNALLADKVI..GKGAAAVVATAG...VKEVYAEVISLPAVNLLRQAG.VSVSWGERVSAIRNRAGDG.WCPLETACREASTAEEAMPVVDGFV...................
R6C3E0_9CLOT/7-135                  ........................l-AKKLME.EDRYTCVICG....EG...ITYF.SEE.....SGVRPLM...QW...TAE.K.IN...-VKGCCAADKIV..GKAAALLYVGLG...VREVYASVMSRRGEETLKKHG.IEAFYGELCEDIRNRTDTD.ICPMEKAVREAETPAEAVEAIKAAI...................
R7DII0_9PORP/4-133                  ........................s-LVNLLH.KENYSCVIFG....LN...ETRT.FSR.....RGVIDLY...DL...LLN.D.RT...FLKRALVADKVV..GKAAASLMILGE...IRELHADVISTPALSLLRNAS.VKVSFGCQVPYIKNRNQDG.WCPLESACFKSVSAISSFRIVQDFM...................
A0A0F0CIW8_9CLOT/5-137              .......................ll--KKVAE.KEALAILTDS....LG..nVIWE.SDK.....SPVAAMY...GQ...YFE.H.QF...----SGVKAMVLyaNQAGIAMGIMAGripIRECHGVRMSEGGLKMFREMG.VAVTYAELIPLVKSSKDDTkVCPIEQFLYDHRDQGEQWEFLEE--rf.................
R7ERT9_9FIRM/6-132                  ...................larenl-------.-GGHTLVLCR....GG...ELMI.SDA.....RGVSPMM...DY...IAE.G.RD...-LRGFSAADVIV..GKATAMLFVKAG...ITAVYAGVVSAAGKKYLEEHG.VPLTFGSVTERIMNRAGTD.SCPMEKAVGGTDDCEEGYILLKKQ-l..................
E1RBY4_SPISS/2-118                  .......................np-------.----SLVAKR....NG..tLFFT.SNG.....RWLYPLF...EL...EEA.C.LHsniSPSDLCVEDSIG..GIAAAGMMLHLG...VRDVHIHILSRLGLDYFRQHG.ITPGWDQLVDKIS------.-CKTEEMLSGTMTPEEIYIFL----kkr................
A0A101HCW7_9FIRM/6-136              ........................i-AKTTLK.TEKLSLVIVK....NG..qIIYK.SDK.....RGIYPLY...MA...VKE.N.GS...RLEGATAADKVI..GRGAAQLYRFAK...VKSIYAYMISEGTKEVFDESR.ITYETEITVPFIKNREGTG.MCPVETLSYEAKTFEELILSMEGF-l..................
F0RZM0_SPHGB/7-128                  ...................plpegt-------.----TLSIYN....HD..qLIFS.DSG.....RWLSPLFafeRF...LAT.Y.TG...ERDCLSAHDTAA..GKAAAVLMSRMG...IARAHINLVSDLAVAFYEEHG.IRITWEKRIERL-------.ACKTEDLLFDLTSEEEMYRLLR---rra................
R7KYZ6_9FIRM/1-98                   .........................-------.----------....--...----.---.....-----MM...KF...IGM.G.KD...-LKGYSAADMIV..GKAASMLFVKAG...ICAVHGKVMSEAASEYLEAHH.IPHSYDKLTEQIINRTGDN.ICPMEAAVANIPDPEEGYKALFNK-i..................
A0A095Y6X0_9BACT/4-103              ........................e-LIDTLH.TERCSLAILH....EG...NIRA.FDG.....HGVRRLY...NI...IND.E.PE...LFLDAKVAVKAV..GRSAARMMKEGN...VAEVYADVISQQAYDVLHDAG.IAVSFEKRVDH--------.-------------------------atf................
U2F271_CLOS4/26-156                 ........................t-LKQEMI.DRGYKCVAGK....GE..gVLFS.SHK.....NGIAPLL...DL...YEA.K.LG...GEGGLCICDRVF..GKAAVFVAYLCG...ARDCYAFVASRPALDLAAELG.MRLDCETEVPFIENRDKTG.QCPIENSVMDCHTPEEALAAIRR--rl.................
C0EAE6_9FIRM/6-134                  ........................q-AKTLLQ.SGGYSCVLCK....GE...RTHT.STE.....RGVLPLV...RI...LSE.N.TH...-LSGFSAADRIV..GKAAALLFCLIG...VKEVYAPVMSRAAVEVLSAHG.ILSSYDTTVETIVNREGTG.ACPMEQAVRELDQPEAALEAVKRT-l..................
D1W0I1_9BACT/6-104                  ........................e-LIDMLH.TEDCSMVLLH....EG...NIRT.FKG.....RGVRTLY...HL...LND.A.PE...SLLKSKTAVKAV..GKTAARAMTEGG...VVEVYADVMSQEAYAWLEDAG.VKVNCEKKVDH--------.-------------------------qr.................
R5VWG9_9FIRM/1-98                   .........................-------.----------....--...----.---.....-----MM...QL...LEQ.K.VD...-LTGYSVADLIV..GKAVAFLFVKAK...IKAVYAKVISRQGLKILNQYH.IDCEYDNLTEQIINREKTD.ICPMEKATQNATNPEEAYLLIKQA-l..................
R6WND3_9BACT/4-133                  ........................e-LVRTLR.EGGHTLVVAN....GA...QIRT.FDR.....RGVADLH...TL...LTD.G.GE...FLRGATVADKVV..GKAAAALMLLGG...VSEMHTEVISRPALDLLAGSG.MRVGYEVEVPHVINRNRTG.WCPLETRCRDCRTARECLERIEEFL...................
R5FEN9_9BACT/3-132                  ........................e-LIDILH.RENCSLVVRD....VH..gEITI.YRK.....PGVRDLE...DL...LRS.D.TE...RLRGADIADKVI..GKAAAGMAVYGG...VHSVYGEVLSRHALPILNEAG.VDYSYGTLVDVIVREMSDM.RCPLEQIVAKCRTPYEIVETL----yhh................
E7RMG5_9BACT/6-105                  ........................e-LIDTLH.TEQCSLVLLH....EG...NVHK.FNG.....RGARTLY...NL...LTE.A.PE...ALLNSKLAAKAA..GRTAAKMMVNGG...VCEVYADVISEQAFSTLKNAG.IKVAFDRKVDH--------.-------------------------aaf................
A0A0P9E773_9ARCH/6-136              ......................lak---LRLK.ERDLTLVIVK....EG..kVIFE.TKP.....QGISDFL...QA...IEK.F.GK...RLVASSVADKIV..GAAAAMLCAYSE...VASVFAVTISEKGIKVLESND.IFYQFEFCVPKILNYDRTD.ICPFEKLAAGSRDPKEAYVKLKSF-a..................
B1C003_9FIRM/6-135                  ......................kgr---RILV.ENGYTFVALK....KD...EIYS.STL.....HGIKPLM...SK...IFV.S.ND...YFKDYIVIDRVI..GRAAALLLIRSK...VKYIHGFILSEPAKDLLEQYH.IDYSYDYLVPYITNRDKNR.MCSLEASVLDVDDLEQGFKIIC---rem................
A0A0G1CV95_9BACT/20-134             .....................rrrg-------.----------....NK...IIFR.SKK.....SGVRGLL...DF...INE.R.GE...IQEGIVIFDKIV..GQAVALLAAYLK...AREVYGGTGSELAAKALEKYK.IKFYFQKTIPNILNQDKTG.LCPFEKLSIDK-SPKEFYNCL----vkk................
A0A087DCQ3_9BIFI/9-141              .......................ra---ELLA.DDALGCVAVHtdadGH..tETLT.GTG.....RGVRPLL...VW...LAE.G.RG...-LAGFCVADRVV..GKGAALLYARLG...VKAVWARTMSESGFATLHAHG.IDAAYGTLVPVILNRRRDG.MCPIERAVEHIDDPASAEPAIRAA-v..................
R6N2P7_9CLOT/5-135                  ........................q-LHELLK.DNGYTLAVLK....GD..qVVFH.SQE.....RGLKPLY...QL...YRQ.Q.PE...LLRDSVIADKVT..GKAAAVLAVLGG...AKEVYSDLISEHAFQVLESGG.VKTRYGGKAPYIINRTKTG.MCPMETLVMDAASPEEGAARLIEF-f..................
#=GC SS_cons                        ........................H-HHHHHH.HTT-SEEEES....SS...EEEE.E--.....STTHHHH...HH...HHH.-.S-...--TT-EEEEEEE..-HHHHHHHHHH-...-SEEEEEEEEHHHHHHHHHTT.--EEEEEEESS-B-SSSSS.B-HHHHHHHT---HHHHHHHHH---TT-................
#=GC seq_cons                       ........................p.hhphLp.ptthohVlhp....ss....lhs..pp.....+GltsLh...ph...lpp.p..p....lpGutlADKll..GKAAAhLhlhuG...lpcVaAsllScsAhclLcptG.IpssasphVshIhNRstss.hCPhEphs.phpsspphh.hlpt.....................
//
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