GenomeNet

Database: Pfam
Entry: TipAS
LinkDB: TipAS
Original site: TipAS 
#=GF ID   TipAS
#=GF AC   PF07739.12
#=GF DE   TipAS antibiotic-recognition domain
#=GF AU   Bateman A, Finn RD
#=GF SE   Pfam-B_8785 (release 14.0)
#=GF GA   23.70 23.70;
#=GF TC   23.70 23.70;
#=GF NC   23.60 23.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12682015
#=GF RT   Structural basis for antibiotic recognition by the TipA class of
#=GF RT   multidrug-resistance transcriptional regulators. 
#=GF RA   Kahmann JD, Sass HJ, Allan MG, Seto H, Thompson CJ, Grzesiek S; 
#=GF RL   EMBO J 2003;22:1824-1834.
#=GF DR   INTERPRO; IPR012925;
#=GF DR   SCOP; 1ny9; fa;
#=GF CC   This domain is found at the C-terminus of some MerR family
#=GF CC   transcription factors. The domain has an alpha-helical 
#=GF CC   globin-like fold [1]. The family includes Mta a central
#=GF CC   regulator of multidrug resistance in Bacillus subtilis.
#=GF SQ   1407
#=GS A0A091A1Y6_PAEMA/149-239  AC A0A091A1Y6.1
#=GS A0A177L3Q5_9BACL/128-242  AC A0A177L3Q5.1
#=GS C6LFE1_9FIRM/121-233      AC C6LFE1.1
#=GS Q186Z8_PEPD6/159-290      AC Q186Z8.1
#=GS I6XXG7_PROPF/129-250      AC I6XXG7.1
#=GS A0A0Q3WRV4_9BACI/135-249  AC A0A0Q3WRV4.1
#=GS R4KGI2_CLOPA/159-289      AC R4KGI2.1
#=GS E2SKI2_9FIRM/131-285      AC E2SKI2.1
#=GS A0A0N0H719_THEVU/125-245  AC A0A0N0H719.1
#=GS I4D2L0_DESAJ/108-243      AC I4D2L0.1
#=GS A0A0Q5QH09_9ACTN/133-247  AC A0A0Q5QH09.1
#=GS U2RNW1_LEIAQ/127-247      AC U2RNW1.1
#=GS A4VTA8_STRSY/124-197      AC A4VTA8.1
#=GS A0A0A6URV8_ACTUT/19-127   AC A0A0A6URV8.1
#=GS A0A059W5G1_STRA9/143-259  AC A0A059W5G1.1
#=GS C6XSR3_PEDHD/138-256      AC C6XSR3.1
#=GS U2EFS0_9FIRM/131-249      AC U2EFS0.1
#=GS A0A0Q7DIM0_9RHIZ/132-251  AC A0A0Q7DIM0.1
#=GS A9WPQ7_RENSM/1-91         AC A9WPQ7.1
#=GS A0A0M2JGI2_9ACTN/131-247  AC A0A0M2JGI2.1
#=GS A0A0A1CZU8_9MICC/132-248  AC A0A0A1CZU8.1
#=GS A0A0Q9N797_9BACL/135-249  AC A0A0Q9N797.1
#=GS F4F6F6_VERMA/131-247      AC F4F6F6.1
#=GS A0QUF9_MYCS2/129-247      AC A0QUF9.1
#=GS R6NDJ1_9CLOT/124-239      AC R6NDJ1.1
#=GS A0A095WPX6_9ACTO/135-250  AC A0A095WPX6.1
#=GS K6D8K5_BACAZ/135-249      AC K6D8K5.1
#=GS A0A0D6W9D8_9ACTN/131-247  AC A0A0D6W9D8.1
#=GS U2DS84_CLOS4/132-247      AC U2DS84.1
#=GS N1ZBD2_9CLOT/136-278      AC N1ZBD2.1
#=GS K6TWB6_9CLOT/135-249      AC K6TWB6.1
#=GS G7M0Y3_9CLOT/159-291      AC G7M0Y3.1
#=GS A0A0W0YVM6_9GAMM/127-247  AC A0A0W0YVM6.1
#=GS A0A069JUZ1_9ACTN/127-241  AC A0A069JUZ1.1
#=GS W7ZGM7_9BACI/135-249      AC W7ZGM7.1
#=GS V5X686_MYCNE/133-247      AC V5X686.1
#=GS B9E9R5_MACCJ/133-248      AC B9E9R5.1
#=GS A0A0Q7KFM9_9ACTN/135-250  AC A0A0Q7KFM9.1
#=GS A0A0A0JRC1_9MICO/137-253  AC A0A0A0JRC1.1
#=GS W5XVP9_9CORY/138-252      AC W5XVP9.1
#=GS R4KGI2_CLOPA/290-380      AC R4KGI2.1
#=GS A0A0U4GRT3_9MICO/130-254  AC A0A0U4GRT3.1
#=GS F9PGI4_9ACTO/161-276      AC F9PGI4.1
#=GS A0A0D0P4L3_KITGR/137-256  AC A0A0D0P4L3.1
#=GS C8NID0_9LACT/129-240      AC C8NID0.1
#=GS A3DJE0_CLOTH/50-164       AC A3DJE0.1
#=GS G2FP82_9FIRM/141-244      AC G2FP82.1
#=GS D0BKK0_9LACT/129-240      AC D0BKK0.1
#=GS A0A0A2U9U5_9BACL/130-242  AC A0A0A2U9U5.1
#=GS A0A0C9N5Z2_SPHPI/126-249  AC A0A0C9N5Z2.1
#=GS A0A087CHS1_9BIFI/131-246  AC A0A087CHS1.1
#=GS Q5ZV30_LEGPH/129-244      AC Q5ZV30.1
#=GS J9H6Z6_9ACTN/4-105        AC J9H6Z6.1
#=GS A0A0P0E4P5_9MICO/129-249  AC A0A0P0E4P5.1
#=GS A0A0F4KRP4_9ACTN/64-180   AC A0A0F4KRP4.1
#=GS A0A059WAJ3_STRA9/181-296  AC A0A059WAJ3.1
#=GS A0A0C2U2T6_BACBA/133-250  AC A0A0C2U2T6.1
#=GS C8NHQ8_9LACT/127-238      AC C8NHQ8.1
#=GS A0A103DYN4_9BURK/145-231  AC A0A103DYN4.1
#=GS D9R5M6_CLOSW/135-249      AC D9R5M6.1
#=GS A0A0Q6PS83_9MICO/132-249  AC A0A0Q6PS83.1
#=GS T1ZDT3_STRIT/129-240      AC T1ZDT3.1
#=GS R7I726_9FIRM/124-239      AC R7I726.1
#=GS B6GE32_9ACTN/22-137       AC B6GE32.1
#=GS A0A150KJL7_9BACI/135-248  AC A0A150KJL7.1
#=GS A0A0W0WHQ7_9GAMM/127-247  AC A0A0W0WHQ7.1
#=GS A0A0B8N3U4_9NOCA/129-246  AC A0A0B8N3U4.1
#=GS G9RTZ6_9FIRM/135-250      AC G9RTZ6.1
#=GS W9GFL3_9MICO/131-247      AC W9GFL3.1
#=GS A0A177L4B0_9BACL/135-249  AC A0A177L4B0.1
#=GS A0A0F7N7L0_9ACTN/130-247  AC A0A0F7N7L0.1
#=GS R7MMV2_9FIRM/129-245      AC R7MMV2.1
#=GS D9TC79_MICAI/131-247      AC D9TC79.1
#=GS A0A0U4F6S0_9BACI/130-242  AC A0A0U4F6S0.1
#=GS Q67PF0_SYMTH/133-247      AC Q67PF0.1
#=GS E1M938_9STRE/18-129       AC E1M938.1
#=GS V2YCN1_9FIRM/135-250      AC V2YCN1.1
#=GS A0A0F4K6K9_9ACTN/134-247  AC A0A0F4K6K9.1
#=GS A0A0J1IZW6_9FIRM/173-287  AC A0A0J1IZW6.1
#=GS A1UNC4_MYCSK/133-247      AC A1UNC4.1
#=GS A6M0Z2_CLOB8/135-249      AC A6M0Z2.1
#=GS U2XQ50_9MICO/137-251      AC U2XQ50.1
#=GS A0A0N1G5Z4_9ACTN/135-248  AC A0A0N1G5Z4.1
#=GS R6BID2_9CLOT/128-242      AC R6BID2.1
#=GS A0A0A1D2F7_9MICC/152-272  AC A0A0A1D2F7.1
#=GS C8WL72_EGGLE/141-257      AC C8WL72.1
#=GS G9EPC7_9GAMM/117-247      AC G9EPC7.1
#=GS A0A0M9ZYR4_9NOCA/129-247  AC A0A0M9ZYR4.1
#=GS A0A0K2YH64_9NOCA/123-239  AC A0A0K2YH64.1
#=GS D4K3E3_9FIRM/124-239      AC D4K3E3.1
#=GS A0A0D4BYV4_9MICC/136-249  AC A0A0D4BYV4.1
#=GS D9RYL1_THEOJ/130-243      AC D9RYL1.1
#=GS A0A0R2ML32_9LACO/143-258  AC A0A0R2ML32.1
#=GS R9KGR4_9FIRM/157-276      AC R9KGR4.1
#=GS S7TJ67_9DELT/142-234      AC S7TJ67.1
#=GS A0A094JNJ0_9BACL/144-242  AC A0A094JNJ0.1
#=GS A0A161I2D3_9MICO/127-247  AC A0A161I2D3.1
#=GS A0A133Q0Q9_STALU/162-282  AC A0A133Q0Q9.1
#=GS U2NP68_9CLOT/158-289      AC U2NP68.1
#=GS A0A089XZL1_9LACO/135-253  AC A0A089XZL1.1
#=GS F2R6G9_STRVP/139-253      AC F2R6G9.1
#=GS A0A0J1F8V9_9FIRM/135-251  AC A0A0J1F8V9.1
#=GS A0A142X773_9PLAN/131-248  AC A0A142X773.1
#=GS A0A0A1G160_9MYCO/116-230  AC A0A0A1G160.2
#=GS C6PMI4_9CLOT/159-303      AC C6PMI4.1
#=GS A0A0N0I5N4_9BACI/131-245  AC A0A0N0I5N4.1
#=GS R6DKG0_9CLOT/132-246      AC R6DKG0.1
#=GS A0A060QC44_9PROT/143-255  AC A0A060QC44.1
#=GS R4T6Y3_AMYOR/132-248      AC R4T6Y3.1
#=GS S9QUQ7_9DELT/12-123       AC S9QUQ7.1
#=GS A0A090IZ28_9BACI/135-249  AC A0A090IZ28.1
#=GS H6NBG0_9BACL/131-248      AC H6NBG0.1
#=GS V9GD24_9BACL/135-249      AC V9GD24.1
#=GS A0A0M0WD31_9BACI/131-243  AC A0A0M0WD31.1
#=GS B1C6A0_9FIRM/159-277      AC B1C6A0.1
#=GS A0A089LT27_9BACL/138-252  AC A0A089LT27.1
#=GS A0A161WJK8_9CLOT/286-382  AC A0A161WJK8.1
#=GS A0A089W542_9ENTR/128-231  AC A0A089W542.1
#=GS W7ISG9_9PSEU/135-250      AC W7ISG9.1
#=GS A8MKF1_ALKOO/132-251      AC A8MKF1.1
#=GS A0A069DHI1_9BACL/135-249  AC A0A069DHI1.1
#=GS H6RL86_BLASD/129-245      AC H6RL86.1
#=GS A0A0R2NJV7_9LACO/133-248  AC A0A0R2NJV7.1
#=GS K6WSU6_9MICO/157-273      AC K6WSU6.1
#=GS E6UB78_RUMA7/124-239      AC E6UB78.1
#=GS A0A101V655_9FIRM/135-249  AC A0A101V655.1
#=GS A0A0A8X760_9BACI/134-247  AC A0A0A8X760.1
#=GS Q24YF4_DESHY/128-242      AC Q24YF4.1
#=GS A0A0W1KK30_9ACTO/102-218  AC A0A0W1KK30.1
#=GS F5SBV8_9BACL/135-249      AC F5SBV8.1
#=GS A0A0F0LMN2_9MICO/139-273  AC A0A0F0LMN2.1
#=GS A0A136Q5H8_9FIRM/136-250  AC A0A136Q5H8.1
#=GS A0A0M2HFG2_9MICO/130-254  AC A0A0M2HFG2.1
#=GS A0A101WS95_9FIRM/135-249  AC A0A101WS95.1
#=GS R6WRY4_9FIRM/14-129       AC R6WRY4.1
#=GS D4LAG1_RUMC1/124-239      AC D4LAG1.1
#=GS J0KMP3_9BURK/1-64         AC J0KMP3.1
#=GS C9Z0V2_STRSW/131-247      AC C9Z0V2.1
#=GS R6QNP8_9FIRM/131-288      AC R6QNP8.1
#=GS A0A0P4UU11_9CYAN/99-212   AC A0A0P4UU11.1
#=GS R3W4H5_9ENTE/135-249      AC R3W4H5.1
#=GS C5R9M2_WEIPA/135-249      AC C5R9M2.1
#=GS A0A0B0I4M1_9BACL/128-231  AC A0A0B0I4M1.1
#=GS A0A0P7ZD01_9EURY/24-89    AC A0A0P7ZD01.1
#=GS U2EFP2_9FIRM/293-382      AC U2EFP2.1
#=GS A0A0E3W3N6_9FIRM/135-249  AC A0A0E3W3N6.1
#=GS A0A150LYQ2_9BACI/128-241  AC A0A150LYQ2.1
#=GS R9NBM6_9FIRM/131-250      AC R9NBM6.1
#=GS A0A0F4JVK0_9ACTN/131-247  AC A0A0F4JVK0.1
#=GS D2NNX6_ROTMD/143-257      AC D2NNX6.1
#=GS J4UH30_9FIRM/129-240      AC J4UH30.1
#=GS A0A0F0EI63_9MICO/131-247  AC A0A0F0EI63.1
#=GS A0A037Z2U6_CLOTT/159-290  AC A0A037Z2U6.1
#=GS A0A0M2PJW2_9BACI/116-245  AC A0A0M2PJW2.1
#=GS A0A0H5CQV0_9PSEU/134-247  AC A0A0H5CQV0.1
#=GS A5N5M3_CLOK5/306-396      AC A5N5M3.1
#=GS B1VT66_STRGG/137-249      AC B1VT66.1
#=GS W4CXR9_9BACL/135-249      AC W4CXR9.1
#=GS Q0SA90_RHOJR/134-249      AC Q0SA90.1
#=GS A0A0Q9MAS5_9MICO/130-246  AC A0A0Q9MAS5.1
#=GS A0A0B0HHU2_9BACI/1-73     AC A0A0B0HHU2.1
#=GS C0ZE86_BREBN/124-242      AC C0ZE86.1
#=GS A0A0M9VME0_9MICO/128-243  AC A0A0M9VME0.1
#=GS K8EE21_CARML/135-250      AC K8EE21.2
#=GS U2EFP2_9FIRM/131-291      AC U2EFP2.1
#=GS D9QEM6_CORP2/131-245      AC D9QEM6.1
#=GS W2EMN9_9ACTN/137-216      AC W2EMN9.1
#=GS F4D0U1_PSEUX/127-240      AC F4D0U1.1
#=GS A0A0A8B5B4_9ACTN/129-240  AC A0A0A8B5B4.1
#=GS A0A0W7W9J5_9MICO/140-256  AC A0A0W7W9J5.1
#=GS A0A176J700_9BACI/135-249  AC A0A176J700.1
#=GS A6LZ00_CLOB8/294-382      AC A6LZ00.1
#=GS A0A0H4KGI5_9BACI/135-249  AC A0A0H4KGI5.1
#=GS E8U4S1_DEIML/131-247      AC E8U4S1.1
#=GS A0A075JJN7_9BACI/130-242  AC A0A075JJN7.1
#=GS A9G076_SORC5/127-239      AC A9G076.1
#=GS A0A161WJK8_9CLOT/159-291  AC A0A161WJK8.1
#=GS A0A0C1QYA9_9CLOT/289-382  AC A0A0C1QYA9.1
#=GS A0A0M8THI3_9ACTN/131-247  AC A0A0M8THI3.1
#=GS V6K0L9_STRNV/1-66         AC V6K0L9.1
#=GS A6TAP5_KLEP7/127-232      AC A6TAP5.1
#=GS S0JSS9_9ENTE/135-249      AC S0JSS9.1
#=GS A0A0A0DJB1_9STRE/129-240  AC A0A0A0DJB1.1
#=GS A0A0H4LCD0_9LACO/135-250  AC A0A0H4LCD0.1
#=GS A0A0F6A9H7_9GAMM/126-255  AC A0A0F6A9H7.1
#=GS A4FQS4_SACEN/129-245      AC A4FQS4.1
#=GS A0A101XRH8_9BACL/95-206   AC A0A101XRH8.1
#=GS K8W0A6_PRORE/146-238      AC K8W0A6.1
#=GS A8MEK2_ALKOO/101-242      AC A8MEK2.1
#=GS Q24PL3_DESHY/135-249      AC Q24PL3.1
#=GS R7WMU5_9NOCA/130-250      AC R7WMU5.1
#=GS R5ZA10_9ACTN/155-270      AC R5ZA10.1
#=GS R2SWP0_9ENTE/135-250      AC R2SWP0.1
#=GS Q816A4_BACCR/130-238      AC Q816A4.1
#=GS A0A0P6WRW7_9BACI/135-249  AC A0A0P6WRW7.1
#=GS A0A0M4FRI0_9BACI/63-217   AC A0A0M4FRI0.1
#=GS U2TEJ5_9ACTN/129-240      AC U2TEJ5.1
#=GS S4Y8P7_SORCE/124-234      AC S4Y8P7.1
#=GS X5DV95_9CORY/145-260      AC X5DV95.1
#=GS F0Z4T7_9CLOT/166-277      AC F0Z4T7.1
#=GS A0A139PBT9_9STRE/129-240  AC A0A139PBT9.1
#=GS K9UQB9_9CYAN/130-242      AC K9UQB9.1
#=GS B7C972_9FIRM/126-241      AC B7C972.1
#=GS M2P9S4_9FIRM/144-252      AC M2P9S4.1
#=GS A0A0A1MA35_9BACI/135-250  AC A0A0A1MA35.1
#=GS W4QNI3_BACA3/128-237      AC W4QNI3.1
#=GS V6IW51_9BACL/135-250      AC V6IW51.1
#=GS W2C1H5_9FIRM/129-240      AC W2C1H5.1
#=GS K6TSN4_9CLOT/132-244      AC K6TSN4.1
#=GS A0A0V8QAF8_9FIRM/135-250  AC A0A0V8QAF8.1
#=GS A0A087M1N4_9RHIZ/133-251  AC A0A087M1N4.1
#=GS A0A0F0HJD5_9PSEU/134-247  AC A0A0F0HJD5.1
#=GS H0DIH4_9STAP/126-240      AC H0DIH4.1
#=GS R9JLS4_9FIRM/124-239      AC R9JLS4.1
#=GS G2P1E6_STRVO/131-247      AC G2P1E6.1
#=GS A0A0M8Y3H8_9ACTN/127-241  AC A0A0M8Y3H8.1
#=GS A0A0C1NKL8_9PSEU/132-244  AC A0A0C1NKL8.1
#=GS A0A151AKP6_9CLOT/135-249  AC A0A151AKP6.1
#=GS A0A0Q8CTQ0_9MICO/127-247  AC A0A0Q8CTQ0.1
#=GS F6FRP8_ISOV2/127-247      AC F6FRP8.1
#=GS A0A0F0LYZ5_9MICO/126-245  AC A0A0F0LYZ5.1
#=GS A0A172TBH8_9DEIO/144-260  AC A0A172TBH8.1
#=GS W6T5M4_9LACO/135-250      AC W6T5M4.1
#=GS N9Y3S5_9CLOT/135-250      AC N9Y3S5.1
#=GS G9WIL8_9LACT/134-249      AC G9WIL8.1
#=GS A0A176QFP3_9MICO/143-257  AC A0A176QFP3.1
#=GS A0A0X3RSU5_9ACTN/132-251  AC A0A0X3RSU5.1
#=GS L8TTR3_9MICC/117-237      AC L8TTR3.1
#=GS W0EB66_9FIRM/135-249      AC W0EB66.1
#=GS SKGA_CAUCR/132-251        AC P0CAV4.1
#=GS Q81XN3_BACAN/130-238      AC Q81XN3.1
#=GS A0A132PG13_9MYCO/136-251  AC A0A132PG13.1
#=GS B1VR73_STRGG/127-241      AC B1VR73.1
#=GS D9X5A2_STRVT/131-247      AC D9X5A2.1
#=GS A0A061AA43_9MOLU/136-249  AC A0A061AA43.1
#=GS B0C952_ACAM1/133-247      AC B0C952.1
#=GS A0A0Q9CWD4_9CELL/141-260  AC A0A0Q9CWD4.1
#=GS L9PI26_9BURK/130-242      AC L9PI26.1
#=GS S0KM78_9ENTE/134-244      AC S0KM78.1
#=GS G7GM85_9ACTN/136-251      AC G7GM85.1
#=GS V9G8E5_9BACL/131-250      AC V9G8E5.1
#=GS A0A023DF49_9BACI/130-243  AC A0A023DF49.1
#=GS F5LQ49_9BACL/127-240      AC F5LQ49.1
#=GS A0A177YA13_9NOCA/130-245  AC A0A177YA13.1
#=GS A0A084J7A3_9CLOT/159-291  AC A0A084J7A3.1
#=GS F2I806_AERUA/124-239      AC F2I806.1
#=GS N2AIT1_9CLOT/16-167       AC N2AIT1.1
#=GS Q2FVM8_STAA8/125-236      AC Q2FVM8.1
#=GS C6PMI4_9CLOT/304-394      AC C6PMI4.1
#=GS R5BVY5_9FIRM/166-278      AC R5BVY5.1
#=GS MTA_BACSU/135-248         AC P71039.1
#=GS A0A176J5B0_9BACI/131-250  AC A0A176J5B0.1
#=GS D9VDA0_9ACTN/132-248      AC D9VDA0.1
#=GS D9W185_9ACTN/131-247      AC D9W185.1
#=GS W4QLJ3_9BACI/13-124       AC W4QLJ3.1
#=GS K9R6W7_9CYAN/126-232      AC K9R6W7.1
#=GS V1CIS8_9FIRM/129-240      AC V1CIS8.1
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#=GS R6R2Q1_9FIRM/160-278      AC R6R2Q1.1
#=GS A0A0P7C0L5_9BACT/127-244  AC A0A0P7C0L5.1
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#=GS A0A172X516_9MICO/127-247  AC A0A172X516.1
#=GS A0A098GJH3_TATMI/126-247  AC A0A098GJH3.1
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#=GS V4QRZ9_STRIN/123-235      AC V4QRZ9.1
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#=GS A0A0F4JYH7_9ACTN/140-256  AC A0A0F4JYH7.1
#=GS D3EDV0_GEOS4/135-249      AC D3EDV0.1
#=GS A0A022MIT1_9ACTN/132-251  AC A0A022MIT1.1
#=GS U2JGV7_9STRE/89-201       AC U2JGV7.1
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#=GS A0A0D3V6G6_9BACL/135-249  AC A0A0D3V6G6.1
#=GS A0A0N8HXU0_9MICC/137-255  AC A0A0N8HXU0.1
#=GS L8EJ21_STRRM/118-233      AC L8EJ21.1
#=GS A0A0M5M3R6_9MICC/10-122   AC A0A0M5M3R6.1
#=GS C6LK68_9FIRM/125-240      AC C6LK68.1
#=GS M0QGF3_9ACTN/140-255      AC M0QGF3.1
#=GS A0A136NU94_9CHLR/130-244  AC A0A136NU94.1
#=GS A0A0F7HNS3_9STAP/130-242  AC A0A0F7HNS3.1
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#=GS A0A0A2TU63_9BACL/138-264  AC A0A0A2TU63.1
#=GS N1V3M0_9MICC/60-175       AC N1V3M0.1
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#=GS R4K193_CLOPA/146-249      AC R4K193.1
#=GS Q8Y9K1_LISMO/128-242      AC Q8Y9K1.1
#=GS Q8Y9K1_LISMO/128-242      DR PDB; 3QAO A; 128-137;
#=GS A0A0Q8RV23_9BURK/133-227  AC A0A0Q8RV23.1
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#=GS A0A132PF64_9MYCO/126-249  AC A0A132PF64.1
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#=GS A0A0R3JSR3_9CLOT/134-248  AC A0A0R3JSR3.1
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#=GS A0A0N0TMD5_9PSEU/130-247  AC A0A0N0TMD5.1
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#=GS A0A109YT07_9MICO/147-275  AC A0A109YT07.1
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#=GS M8DA69_9BACL/132-245      AC M8DA69.1
#=GS R5X1H1_9FIRM/124-239      AC R5X1H1.1
#=GS S1QXP9_9ENTE/135-251      AC S1QXP9.1
#=GS A0A0K2YTR5_9NOCA/128-258  AC A0A0K2YTR5.1
#=GS A0A0F0LK67_9MICO/152-276  AC A0A0F0LK67.1
#=GS A0A117S9N4_9FIRM/135-249  AC A0A117S9N4.1
#=GS A0A094YXV0_BACAO/136-224  AC A0A094YXV0.1
#=GS A0A0C1VPK0_9ACTN/10-123   AC A0A0C1VPK0.1
#=GS D3F749_CONWI/135-251      AC D3F749.1
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#=GS L9UC67_9GAMM/148-254      AC L9UC67.1
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N2AIT1_9CLOT/16-167                  .................................tddlikhwgsienfdmfiqkikddeseva--KVAIQQFGS..iEKyte...............................tmkyNLEH.FS....EFM........KTQ.LTE.D....V...K....EIG...KQ....SDMLYGRLTADL..--S.E..DVSSPKI.QSIVYELLQFIQ........KNST..Sv.............sLDKP....CINVLIV.T.YS......ND.Y-...............IK..NMTDGK............Y..gKG....ASDYIVKAFRYY...............................
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A0A0A1MBZ4_9BACI/131-249             ..............................................................YQMEAKYVYGD...TD......................................KYQE.YE....KNI........KQI.PEE.EraavF...E....AFD...QN....MQDVFMQFAKL-..-SE.E..SPASEKV.QQIVLEWKSYLE........QFMI..-...............GDTE....ILQCIAY.T.YK......ED.KS...............FK..AYINQF............G..nDT....LNEFIHQAILY-h..............................
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A0A0R1YX80_9LACO/133-249             ..............................................................YGQEIREKYGE...ET......................................-VAA.SN....QKF........QNL.TEE.Q....M...K....RFD...EI....QVEIGQKLQEYI..-TG.G..KDSEDLA.RQIFTLHKEFLQ........MTWP..S...............YSAE....AHRGLGE.M.YV......AD.PR...............FR..KYYQDA............Ag.nLD....AATTLNEIIQKY...............................
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C0W4W0_9ACTO/157-271                 ..............................................................WEEEAERRWGD...TE......................................DWKV.ST....RRM........ASM.SRE.D....L...E....VAK...KR....IERVEEQLAQAL..REG.V..EPGSERA.NALAEEHRACMS........--WF..D...............VTRS....KHVLIAC.N.YV......QD.PR...............FA..AHYDER............E...PG....LARWLKDVIDAN...............................
A0A0W1NID1_9ACTN/141-257             ..............................................................YEDEVRERWGD...TD......................................AYRQ.SR....QRT........ASY.TKE.D....W...K....RVT...EE....LDSLHRRMADLM..SAG.T..PADSGDA.MDAAEEHRLFVT........RAYY..D...............CGHE....MHTCLGE.M.YV......AD.PR...............FT..RTYESI............R...PG....LAVYLRDAIVA-n..............................
R7GCG1_9FIRM/141-252                 .......................................................neyywli------KHFDD...TT......................................-LDH.IR....---........NRF.DKE.S....G...M....DFM...QR....FNEISDKVIKLK..EAH.V..APEDTQA.QALAQEFWAMVM........EFTN..-...............GDMS....MLSTLVK.F.--......--.--...............--..------............-...--....------------ddlsddnnawlekqktvnaylqpalely...
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A0A059W4B2_STRA9/132-251             ..............................................................YATDADRKWHD...SD......................................GYRR.SM....ARA........ATH.TKD.D....W...T....QLM...AE....ATAWRARLTAAF..DTG.E..PADGERA.MDLAEEHRRHLT........RWFT..P...............CPTD....MHGRIAD.D.FA......AD.PRaf...........alLV..PPTE-Q............R...PG....LAPYLRTAVHAN...............................
A0A0R1MZ79_9LACO/133-249             .............................................................f-GSEIREKYGE...EK......................................-VSA.AN....KQY........AGL.SEA.D....Y...N....AMQ...DT....ESKMLTLLKAVI..QSG.Q..-IDSPEA.QQVFSLHKAWLQ........FTWP..T...............YSTE....AHKGLAQ.M.YT......AD.PR...............FG..QYYAAK............Tg.sDK....AASVLAAIIEKY...............................
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A0A024P8G5_9BACI/134-248             ..............................................................YEKEVEERWGD...TE......................................AYKE.SK....RKT........NNY.TDE.D....W...K....RIQ...EE....SNRIDRELVKLM..--G.R..DPSDEEV.QRLIGEKRQHIT........DNFY..E...............CKGE....IFRGLAD.M.YV......ND.PR...............FT..KNIDKW............K...EG....YAEFLKKAIHTY...............................
A0A0X3VNU0_9ACTN/158-272             .............................................................v--AEAEERWGD...SA......................................QWAQ.YA....ERA........AAL.SAE.D....W...K....DVA...AT....THALNADLAAAC..RAG.V..APGSDEA.NALAERHRALMS........TYFD..-...............CTHA....MQACLGR.L.FT......DD.PR...............YA..SYYDAL............A...PG....LTLWLRAVF---fan............................
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A0A136PH30_9BACT/134-245             ............................................................ne---WVKEYYTP...EQ......................................-LDA.IE....---........KRA.TPE.T....I...T....QGQ...QA....WGQLIADIEEAA..ANG.V..DPASAEA.QTLIQRQESLIE........GFTG..-...............GDAG....TRENLNK.L.WS......DK.SN...............WP..ATFKSP............Y..sPA....AEAFLEQARKH-n..............................
A0A073BDV6_9PSEU/134-250             ..............................................................YEAEAEQRWGR...TD......................................AYRQ.SR....QRM........SRY.TKQ.D....W...Q....RFL...AE....QQDIHERFAQAL..RSG.L..PADGEHA.MGLAEQHRQHIT........RWCY..D...............CDYG....IHRGLGE.M.YV......SD.ER...............FT..AVYEDI............E...PG....LAEYVRTAIEAN...............................
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A0A0M4QJG7_9MICC/74-185              ..................................................svpdalrrhvaw-----------...--......................................----.--....---........WGL.DTT.Q....K...Q....AWK...DS....VASLNNDWITAS..TSG.V..TPDSPQA.QELARRYVQWLR........SIPG..Tlat........apggDVRS....YVLGLAE.M.YV......AD.GR...............FG..ANYGRA............-...-G....GAGLVRGAL---vif............................
A0A0L8F2S2_9CLOT/303-393             ...........................................................lgd-----------...--......................................----.--....---........---.---.-....-...-....-YE...PK....IEKLYKKLRADL..--S.K..DPTSNEI.QQIVFEIAKETR........RQN-..Evl..........kvdSGEN....FFGYMAD.F.YL......SK.PT...............FI..KATDKK............Y..gEG....AAKFIGEAFKFY...............................
M3BQA5_STRMB/130-251                 ..............................................................YEDEVVARWGE...RA......................................-FRL.SN....EWW........HGK.DMR.E....Q...L....AWK...RD....TDELVDAWATAW..REG.A..SPRSDRA.QALAARHVAWLG........AIPG..Tpvad.......gdreQAGL....MVRCLGD.M.YV......TD.PD...............FA..TTYGSV............-...-E....GAAFVRDALHEY...............................
A0A0A6X0J2_ACTUT/129-246             ..........................................................teea----LAARYGDg.vRE......................................HFAA.AG....ERT........KGW.TRQ.D....Y...L....DAQ...KE....GERLDARVLQLL..RCG.V..APETPEA.LDVIADHHRAVA........RHWS..-...............PDKV....SYAGLGQ.L.YL......DD.PQ...............YR..ARYDAQ............D...PA....LARYYRDAITAY...............................
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A0A089Y6Y5_9LACO/1-99                ............................................................mt-----------...--......................................----.--....-KA........DQF.TDE.N....Y...N....QMK...QT....EADLIRDLQAVV..KEP.E..-KEAELS.VEIFKKHQKWLQ........IIMP..N...............YSPE....IHLGIVS.A.YD......TD.TR...............YQ..SYYDDK............A..gKG....ATKILSRIVK--kh.............................
A0A076MZH0_AMYME/134-247             .............................................................l-AEEAVERWGE...DA......................................--VQ.SH....ERS........KRW.SDE.K....W...D....AVK...RQ....GAEAAERLAELL..REG.V..PADDERA.LDAVAAHRAWLE........SFWT..-...............PDAE....SYTGLGR.L.YS......DD.ER...............FR..GVYEAI............H...PG....LAEYLRDAMAAY...............................
A0A170XFI4_9ACTN/133-249             ..............................................................YEDEVRERWGD...TD......................................AYRQ.SR....QRT........ASY.TKE.D....W...K....RLV...EE....QDGIHRRMADLL..AAG.I..PADSQEA.MDTAEEHRQFIV........RAYY..D...............CGYE....MHTCLGE.M.YV......SD.ER...............FT..RTYEKI............R...PG....LAVYMRDAIVA-n..............................
A0A0R1MB76_9LACO/135-253             ..............................................................YGKEVRRKYGN...MV......................................-VDN.SN....QKF........NSL.SED.E....M...T....HLQ...DL....TKQILSMLKTFV..-GI.H..DLDQPAA.KHLFELHKEFLC........ITWP..Rg.............qYSSE....AHKGLAA.M.YA......SD.PR...............FI..KYYEEG............Tg.kKG....AAKALRAIIDNY...............................
A0A081EKJ1_STRFR/127-242             .............................................................h-KEEVIERWGR...DA......................................-YES.SD....RWW........RSL.GDE.G....R...Q....SFQ...QR....ELDIALDFGKAA..RAG.A..SPDSEEA.QAITRRHYTWLS........DASP..D...............PSKG....YFIGLAE.M.YV......AD.PR...............FA..AHYDRH............G...EG....VAEFVRDAMKVY...............................
A0A0R2HYX4_CARDV/133-250             ............................................................dqYGTESRALYGT...NQ......................................-VID.SN....QKM........LNM.NQE.K....F...Q....AFE...EL....EEAIFVQLKKAM..-NT.K..NVSSIES.QKLARMHKEWLS........YTWT..T...............YSTK....AHVGLVN.L.YL......AD.PR...............FV..SYYDNR............V..gQG....GTQFLKDAVIH-f..............................
D3ALE1_9CLOT/6-63                    ..............................................aqycfqcseyscekyd-----------...--......................................----.--....---........---.---.-....-...-....---...--....------------..---.-..-------.------------........----..-...............HIDD....MLMYLGE.L.YQ......TD.ER...............FV..EYINRF............A..tWN....VAEFFCEAIKVY...............................
X5KVZ3_9MYCO/137-251                 ..............................................................YAEEAQQRWGD...TE......................................EWRQ.SQ....ERT........AKM.TKR.D....W...I....EFK...AE....NDALLQALAAGK..RSG.V..EAGSAAA.NALAARHRANIS........RFFD..-...............CSDD....MHMCLAR.I.YV......ED.ER...............YG..NYYDDA............E...PG....LAQFVHDIIV--a..............................
A0A0X3VGZ5_9ACTN/131-247             ..............................................................YAEEAEQRWGG...TE......................................AYAE.SQ....RRA........ATY.TKA.D....W...K....RLM...AE....ADDWSERYVALM..AAG.E..TPTGEAA.MDMAEEHRAHIG........TWYY..E...............CPYE....MHQCLGE.M.YV......SD.ER...............FK..AFYDAM............R...PG....LAEHLRDAILA-n..............................
A0A0L8F3A3_9CLOT/135-249             .............................................................f-GKEIREKYGN...EQ......................................-IDK.SN....KVF........KNL.TKE.Q....Y...D....NLE...KL....GHDVIDTLKAAF..LTG.D..-PAGKLA.QKAADLHHQWLS........LSWG..E...............YTKE....AHAGVAQ.M.YV......DD.ER...............FT..AYYDKY............Q...PG....LAKFLRDAVLIY...............................
H6N069_GORPV/138-253                 ..............................................................YADEAQERWGD...TA......................................AWQQ.SQ....QRT........AGY.SKD.D....W...R....RIK...EE....TDAFEARVADAM..GRG.V..SPGSAEA.DALAEQHRAAIE........KFYD..-...............CGYE....MQVCLAD.M.YV......AD.PR...............FT..EHYDGV............A...PG....LATYLREIIRAN...............................
A0A150YKB4_9BACI/133-248             ..............................................................YGKEIRERYGN...ET......................................-IEA.SN....KKW........LNM.TEQ.Q....F...E....EMG...QL....EQSLFERLQEAM..TEG.N..-PASQLG.NEVAELHKRWLM........FSWK..D...............YSKE....AHAGLAA.M.YV......AD.ER...............FT..AYYDER............V..aVG....ASQFLHDCIVAY...............................
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#=GC SS_cons                         ..............................................................T--HHHHH--X...XX......................................-XXX.XX....XXX........XXX.XXX.X....X...X....XXX...XX....XXXXXXXXXXXX..--X.X..XXXXXXX.XXXXXXXXXXXX........XXXX..X..............XXXXX....XXXXXXX.X.XX......XX.XX...............XX..XXXXXX............X...XX....XXXXXXXXXXXX...............................
#=GC seq_cons                        ..............................................................atpEspp+aGp...pt.......................................hpp.up....pch........tsh.opp.c....h...p....php...pp....hpplhpplspsh..ttG.t..sssuppu.pplscc+ppals........phat..p...............sstc....hatuLuc.h.Yl......sD.tR...............Fp..tha-ph............t...sG....hApalpcAlth................................
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