GenomeNet

Database: Pfam
Entry: TipAS
LinkDB: TipAS
Original site: TipAS 
#=GF ID   TipAS
#=GF AC   PF07739.10
#=GF DE   TipAS antibiotic-recognition domain
#=GF AU   Bateman A, Finn RD
#=GF SE   Pfam-B_8785 (release 14.0)
#=GF GA   23.70 23.70;
#=GF TC   23.70 24.00;
#=GF NC   23.30 23.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12682015
#=GF RT   Structural basis for antibiotic recognition by the TipA class of
#=GF RT   multidrug-resistance transcriptional regulators. 
#=GF RA   Kahmann JD, Sass HJ, Allan MG, Seto H, Thompson CJ, Grzesiek S; 
#=GF RL   EMBO J 2003;22:1824-1834.
#=GF DR   INTERPRO; IPR012925;
#=GF DR   SCOP; 1ny9; fa;
#=GF CC   This domain is found at the C-terminus of some MerR family
#=GF CC   transcription factors. The domain has an alpha-helical 
#=GF CC   globin-like fold [1]. The family includes Mta a central
#=GF CC   regulator of multidrug resistance in Bacillus subtilis.
#=GF SQ   504
#=GS R6RAB1_9FIRM/133-276      AC R6RAB1.1
#=GS S0SC88_9ENTE/135-248      AC S0SC88.1
#=GS G9WK54_9FIRM/129-240      AC G9WK54.1
#=GS E3GLN9_EUBLK/136-251      AC E3GLN9.1
#=GS Q186Z8_PEPD6/159-290      AC Q186Z8.1
#=GS I6XXG7_PROPF/129-250      AC I6XXG7.1
#=GS D4J1Z6_BUTFI/124-239      AC D4J1Z6.1
#=GS D4MPU0_9FIRM/127-242      AC D4MPU0.1
#=GS Q65NV1_BACLD/130-244      AC Q65NV1.1
#=GS I4EQR9_MODMB/131-247      AC I4EQR9.1
#=GS C8W600_DESAS/135-249      AC C8W600.1
#=GS A0A0B5DE79_9CORY/128-239  AC A0A0B5DE79.1
#=GS A0A0D4DHA8_9ACTN/136-249  AC A0A0D4DHA8.1
#=GS F4H6H4_CELFA/127-246      AC F4H6H4.1
#=GS Q8ET80_OCEIH/135-250      AC Q8ET80.1
#=GS R4KGI2_CLOPA/159-289      AC R4KGI2.1
#=GS B4EXM3_PROMH/250-336      AC B4EXM3.1
#=GS C2X5M7_BACCE/78-196       AC C2X5M7.1
#=GS B9DIW4_STACT/135-253      AC B9DIW4.1
#=GS A8MEH9_ALKOO/131-249      AC A8MEH9.1
#=GS U5L4H3_9BACI/130-242      AC U5L4H3.1
#=GS H6LGN6_ACEWD/128-242      AC H6LGN6.1
#=GS Q65NY5_BACLD/134-246      AC Q65NY5.1
#=GS D3Q6A7_STANL/145-260      AC D3Q6A7.1
#=GS I4D2L0_DESAJ/108-243      AC I4D2L0.1
#=GS I2EPZ2_EMTOG/133-251      AC I2EPZ2.1
#=GS Q6NKD0_CORDI/138-253      AC Q6NKD0.1
#=GS B2HI54_MYCMM/129-247      AC B2HI54.1
#=GS D7CGC9_STRBB/131-247      AC D7CGC9.1
#=GS E7GQR6_CLOSY/124-241      AC E7GQR6.1
#=GS A0A0D1Y6Z9_ANEMI/125-245  AC A0A0D1Y6Z9.1
#=GS F0SUR9_SYNGF/136-250      AC F0SUR9.1
#=GS A0A0A7FW07_9CLOT/135-249  AC A0A0A7FW07.1
#=GS Q5WJB9_BACSK/135-249      AC Q5WJB9.1
#=GS R6JVQ6_9CLOT/131-250      AC R6JVQ6.1
#=GS K0EKU1_9NOCA/129-246      AC K0EKU1.1
#=GS S6CEE1_9ACTN/159-276      AC S6CEE1.1
#=GS A0A089M6B8_9BACL/135-249  AC A0A089M6B8.1
#=GS A4VTA8_STRSY/124-197      AC A4VTA8.1
#=GS E9T247_RHOHA/131-248      AC E9T247.1
#=GS F8A071_CELGA/127-246      AC F8A071.1
#=GS Q24WX8_DESHY/154-249      AC Q24WX8.1
#=GS A0A059W5G1_STRA9/143-259  AC A0A059W5G1.1
#=GS C6XSR3_PEDHD/138-256      AC C6XSR3.1
#=GS B2TN80_CLOBB/288-381      AC B2TN80.1
#=GS A9WPQ7_RENSM/1-91         AC A9WPQ7.1
#=GS I6SVJ3_ENTHA/135-249      AC I6SVJ3.1
#=GS U5RY41_9CLOT/292-381      AC U5RY41.1
#=GS A0A0A1CZU8_9MICC/132-248  AC A0A0A1CZU8.1
#=GS R6PF37_9FIRM/136-251      AC R6PF37.1
#=GS W5THG7_9NOCA/132-245      AC W5THG7.1
#=GS D2QF51_SPILD/131-250      AC D2QF51.1
#=GS B2TMQ3_CLOBB/135-249      AC B2TMQ3.1
#=GS V4I2K5_9ACTN/131-247      AC V4I2K5.1
#=GS G2IKD4_9SPHN/139-254      AC G2IKD4.1
#=GS A0A0D5VLF7_9BURK/123-230  AC A0A0D5VLF7.1
#=GS F4F6F6_VERMA/131-247      AC F4F6F6.1
#=GS A0A077JAQ1_9BACI/135-249  AC A0A077JAQ1.1
#=GS A8AUT7_STRGC/129-240      AC A8AUT7.1
#=GS J9REP7_9ACTN/135-250      AC J9REP7.1
#=GS S0KJK1_ENTAV/135-248      AC S0KJK1.1
#=GS R6NDJ1_9CLOT/124-239      AC R6NDJ1.1
#=GS A0QUF9_MYCS2/129-247      AC A0QUF9.1
#=GS R6YJH3_9FIRM/131-250      AC R6YJH3.1
#=GS B8I2Y9_CLOCE/135-249      AC B8I2Y9.1
#=GS B1VZX4_STRGG/145-259      AC B1VZX4.1
#=GS G4KX02_OSCVS/126-240      AC G4KX02.1
#=GS F2I803_AERUA/20-131       AC F2I803.1
#=GS B7GJ11_ANOFW/146-260      AC B7GJ11.1
#=GS G7M0Y3_9CLOT/159-291      AC G7M0Y3.1
#=GS U2RGX8_9FIRM/135-250      AC U2RGX8.1
#=GS A0A089W542_9ENTR/234-338  AC A0A089W542.1
#=GS V5X686_MYCNE/133-247      AC V5X686.1
#=GS K0F122_9NOCA/155-270      AC K0F122.1
#=GS C6PMP1_9CLOT/128-242      AC C6PMP1.1
#=GS T0TB53_9STRE/1-76         AC T0TB53.1
#=GS I0DSG4_PROSM/139-240      AC I0DSG4.1
#=GS B9E9R5_MACCJ/133-248      AC B9E9R5.1
#=GS V9W755_9BACL/76-196       AC V9W755.1
#=GS B5HI96_STRPR/131-247      AC B5HI96.1
#=GS G7M5F8_9CLOT/290-384      AC G7M5F8.1
#=GS W5XVP9_9CORY/138-252      AC W5XVP9.1
#=GS R4KGI2_CLOPA/290-380      AC R4KGI2.1
#=GS U5RY41_9CLOT/127-291      AC U5RY41.1
#=GS A7GUG0_BACCN/130-238      AC A7GUG0.1
#=GS A5N5M3_CLOK5/159-305      AC A5N5M3.1
#=GS H6NN00_9BACL/157-277      AC H6NN00.1
#=GS R7BFR9_9FIRM/128-243      AC R7BFR9.1
#=GS F8JQ49_STREN/132-251      AC F8JQ49.1
#=GS F2F7P0_SOLSS/133-248      AC F2F7P0.1
#=GS A8GBH1_SERP5/146-231      AC A8GBH1.1
#=GS D4K8A0_9FIRM/124-239      AC D4K8A0.1
#=GS A3DJE0_CLOTH/50-164       AC A3DJE0.1
#=GS E0S068_BUTPB/127-242      AC E0S068.1
#=GS R6RAS7_9FIRM/121-204      AC R6RAS7.1
#=GS D0LDC3_GORB4/140-255      AC D0LDC3.1
#=GS A0A0A2U9U5_9BACL/130-242  AC A0A0A2U9U5.1
#=GS W5Y3U0_9CORY/137-249      AC W5Y3U0.1
#=GS Q82EF8_STRAW/131-247      AC Q82EF8.1
#=GS D4L163_9FIRM/1-51         AC D4L163.1
#=GS A0A060M0K8_9BACI/135-247  AC A0A060M0K8.1
#=GS Q5ZV30_LEGPH/129-244      AC Q5ZV30.1
#=GS A0A0B5DMX9_9ACTN/131-247  AC A0A0B5DMX9.1
#=GS R4K545_CLOPA/135-249      AC R4K545.1
#=GS C8X7X1_NAKMY/131-246      AC C8X7X1.1
#=GS K8W0A6_PRORE/242-335      AC K8W0A6.1
#=GS A0A059WAJ3_STRA9/181-296  AC A0A059WAJ3.1
#=GS U5RYT3_9CLOT/135-249      AC U5RYT3.1
#=GS D9R5M6_CLOSW/135-249      AC D9R5M6.1
#=GS Q5WAV4_BACSK/131-246      AC Q5WAV4.1
#=GS R7I726_9FIRM/124-239      AC R7I726.1
#=GS T1ZDT3_STRIT/129-240      AC T1ZDT3.1
#=GS R7GCG1_9FIRM/144-252      AC R7GCG1.1
#=GS J7IMN6_DESMD/135-249      AC J7IMN6.1
#=GS D6EAJ4_9ACTN/143-260      AC D6EAJ4.1
#=GS C0ZYF5_RHOE4/142-262      AC C0ZYF5.1
#=GS E8N6W8_MICTS/129-244      AC E8N6W8.1
#=GS B1HY28_LYSSC/135-250      AC B1HY28.1
#=GS B9TKV2_RICCO/85-161       AC B9TKV2.1
#=GS R7MMV2_9FIRM/129-245      AC R7MMV2.1
#=GS D9TC79_MICAI/131-247      AC D9TC79.1
#=GS G2TPU5_BACCO/128-241      AC G2TPU5.1
#=GS Q67PF0_SYMTH/133-247      AC Q67PF0.1
#=GS E3PV68_CLOSD/129-237      AC E3PV68.1
#=GS A0A0D5EPD3_9BURK/129-231  AC A0A0D5EPD3.1
#=GS D4JAA8_9FIRM/124-239      AC D4JAA8.1
#=GS C7NFV2_KYTSD/148-264      AC C7NFV2.1
#=GS B5HBN1_STRPR/138-252      AC B5HBN1.2
#=GS A1UNC4_MYCSK/133-247      AC A1UNC4.1
#=GS A6M0Z2_CLOB8/135-249      AC A6M0Z2.1
#=GS D6XYD1_BACIE/135-248      AC D6XYD1.1
#=GS R5FZI0_9ACTN/139-256      AC R5FZI0.1
#=GS K4QWT6_9ACTN/132-251      AC K4QWT6.1
#=GS V6KDP5_STRRC/134-250      AC V6KDP5.1
#=GS R6UZG8_9FIRM/159-285      AC R6UZG8.1
#=GS A0A098GJH3_TATMI/126-247  AC A0A098GJH3.1
#=GS A1S937_SHEAM/39-90        AC A1S937.1
#=GS R6BID2_9CLOT/128-242      AC R6BID2.1
#=GS R7R3D7_9FIRM/1-83         AC R7R3D7.1
#=GS A0A059MHR5_9NOCA/129-248  AC A0A059MHR5.1
#=GS A0A0A1D2F7_9MICC/152-272  AC A0A0A1D2F7.1
#=GS C8WL72_EGGLE/141-257      AC C8WL72.1
#=GS G8SMB8_ACTS5/10-123       AC G8SMB8.1
#=GS A0A099W3B0_9LIST/135-249  AC A0A099W3B0.1
#=GS D4K3E3_9FIRM/124-239      AC D4K3E3.1
#=GS A5N530_CLOK5/135-249      AC A5N530.1
#=GS B5HYC8_9ACTN/131-247      AC B5HYC8.1
#=GS R7FXK0_9FIRM/166-278      AC R7FXK0.1
#=GS R2SJT2_9ENTE/135-250      AC R2SJT2.1
#=GS X4R9D0_9ACTO/127-243      AC X4R9D0.1
#=GS D9RYL1_THEOJ/130-243      AC D9RYL1.1
#=GS Q1D249_MYXXD/133-249      AC Q1D249.1
#=GS G0FX82_AMYMS/127-237      AC G0FX82.1
#=GS E3GLV2_EUBLK/131-284      AC E3GLV2.1
#=GS Q97DK1_CLOAB/126-240      AC Q97DK1.1
#=GS Q11SP4_CYTH3/132-250      AC Q11SP4.1
#=GS D7BPQ0_ARCHD/133-248      AC D7BPQ0.1
#=GS W9EG37_9LACO/5-117        AC W9EG37.1
#=GS Q8DY38_STRA5/123-235      AC Q8DY38.1
#=GS R7QYL2_9FIRM/124-239      AC R7QYL2.1
#=GS Q182Q2_PEPD6/135-249      AC Q182Q2.1
#=GS B4EAB2_BURCJ/126-229      AC B4EAB2.1
#=GS A0A089XZL1_9LACO/135-253  AC A0A089XZL1.1
#=GS F2R6G9_STRVP/139-253      AC F2R6G9.1
#=GS A8MM58_ALKOO/135-249      AC A8MM58.1
#=GS V4QRZ9_STRIN/123-235      AC V4QRZ9.1
#=GS A0A088T1J9_9MOLU/154-249  AC A0A088T1J9.1
#=GS R6ESL2_9FIRM/137-252      AC R6ESL2.1
#=GS K4J0T8_BIFAP/139-253      AC K4J0T8.1
#=GS I0K261_9BACT/133-251      AC I0K261.1
#=GS A0A0A1G160_9MYCO/116-230  AC A0A0A1G160.2
#=GS A4JEI7_BURVG/247-337      AC A4JEI7.1
#=GS Q5Z3H6_NOCFA/134-251      AC Q5Z3H6.1
#=GS Q7NF69_GLOVI/128-241      AC Q7NF69.1
#=GS D3EDV0_GEOS4/135-249      AC D3EDV0.1
#=GS R5L3H7_9CLOT/144-252      AC R5L3H7.1
#=GS D5DGX6_BACMD/130-243      AC D5DGX6.1
#=GS C6PMI4_9CLOT/159-303      AC C6PMI4.1
#=GS R6DKG0_9CLOT/132-246      AC R6DKG0.1
#=GS A0A060QC44_9PROT/143-255  AC A0A060QC44.1
#=GS R4T6Y3_AMYOR/132-248      AC R4T6Y3.1
#=GS U2JGV7_9STRE/89-201       AC U2JGV7.1
#=GS F9VJX7_ARTSS/1-69         AC F9VJX7.1
#=GS A0A097II53_9CORY/127-238  AC A0A097II53.1
#=GS A0A0B5ALS0_9BACL/127-240  AC A0A0B5ALS0.1
#=GS A0A0D3V6G6_9BACL/135-249  AC A0A0D3V6G6.1
#=GS H6NBG0_9BACL/131-248      AC H6NBG0.1
#=GS A0A089LT27_9BACL/138-252  AC A0A089LT27.1
#=GS C1ACC7_GEMAT/128-245      AC C1ACC7.1
#=GS S0L060_9ENTE/135-251      AC S0L060.1
#=GS B4EXM3_PROMH/147-237      AC B4EXM3.1
#=GS Q8DWA6_STRMU/125-243      AC Q8DWA6.1
#=GS F2JGE0_CELLD/135-251      AC F2JGE0.1
#=GS Q9KFR9_BACHD/130-244      AC Q9KFR9.1
#=GS A8MKF1_ALKOO/132-251      AC A8MKF1.1
#=GS H6RL86_BLASD/129-245      AC H6RL86.1
#=GS A0A0D5EPD3_9BURK/247-337  AC A0A0D5EPD3.1
#=GS A0A089ML91_9BACL/131-245  AC A0A089ML91.1
#=GS R7I438_9CLOT/175-290      AC R7I438.1
#=GS A0A0A7KHY7_9DEIO/143-259  AC A0A0A7KHY7.1
#=GS A0A0A2TU63_9BACL/138-264  AC A0A0A2TU63.1
#=GS E6UB78_RUMA7/124-239      AC E6UB78.1
#=GS Q24YF4_DESHY/128-242      AC Q24YF4.1
#=GS I3DUC5_BACMT/134-243      AC I3DUC5.1
#=GS R5BVY5_9FIRM/135-278      AC R5BVY5.1
#=GS D1C932_SPHTD/123-263      AC D1C932.1
#=GS G0FY56_AMYMS/127-246      AC G0FY56.1
#=GS E4NED4_KITSK/138-254      AC E4NED4.1
#=GS K4QWJ7_9ACTN/131-247      AC K4QWJ7.1
#=GS G8QVD2_SPHPG/128-242      AC G8QVD2.1
#=GS A0A0D5EEW0_9BURK/127-206  AC A0A0D5EEW0.1
#=GS R6Z350_9ACTN/144-261      AC R6Z350.1
#=GS M1N0A5_9CORY/132-242      AC M1N0A5.1
#=GS R7D5J5_9ACTN/155-270      AC R7D5J5.1
#=GS C4IGB1_CLOBU/128-242      AC C4IGB1.1
#=GS F2REM4_STRVP/127-241      AC F2REM4.1
#=GS R4K193_CLOPA/146-249      AC R4K193.1
#=GS Q8Y9K1_LISMO/128-242      AC Q8Y9K1.1
#=GS R6WRY4_9FIRM/14-129       AC R6WRY4.1
#=GS U2SS57_9FIRM/7-93         AC U2SS57.1
#=GS D4LAG1_RUMC1/124-239      AC D4LAG1.1
#=GS R6G124_9CLOT/135-249      AC R6G124.1
#=GS C9Z0V2_STRSW/131-247      AC C9Z0V2.1
#=GS R6QNP8_9FIRM/131-288      AC R6QNP8.1
#=GS A0A089X906_STRGA/131-247  AC A0A089X906.1
#=GS A6WA27_KINRD/119-236      AC A6WA27.1
#=GS TIPA_STRCO/131-247        AC P0A4T8.1
#=GS R3W4H5_9ENTE/135-249      AC R3W4H5.1
#=GS W5W6A5_9PSEU/132-249      AC W5W6A5.1
#=GS G4L442_TETHN/135-250      AC G4L442.1
#=GS A5N002_CLOK5/134-244      AC A5N002.1
#=GS A0A089W542_9ENTR/127-231  AC A0A089W542.1
#=GS A0A059VTE8_STRA9/132-246  AC A0A059VTE8.1
#=GS A0A0A7I8J3_9BIFI/124-238  AC A0A0A7I8J3.1
#=GS F0RJJ1_DEIPM/134-250      AC F0RJJ1.1
#=GS K0J1M5_AMPXN/45-153       AC K0J1M5.1
#=GS A0A0D1W880_ANEMI/135-249  AC A0A0D1W880.1
#=GS D2Q340_KRIFD/129-243      AC D2Q340.1
#=GS A9KS32_CLOPH/131-286      AC A9KS32.1
#=GS V5XTL2_ENTMU/135-249      AC V5XTL2.1
#=GS D2NNX6_ROTMD/143-257      AC D2NNX6.1
#=GS C7MEY5_BRAFD/142-257      AC C7MEY5.1
#=GS A5N5M3_CLOK5/306-396      AC A5N5M3.1
#=GS B1VT66_STRGG/137-249      AC B1VT66.1
#=GS Q0SA90_RHOJR/134-249      AC Q0SA90.1
#=GS A0A0B5AQM1_9BACL/135-249  AC A0A0B5AQM1.1
#=GS A0A023X6D8_9ACTN/131-247  AC A0A023X6D8.1
#=GS E8JYP6_9STRE/129-240      AC E8JYP6.1
#=GS J7ISA5_DESMD/111-244      AC J7ISA5.1
#=GS C7MML7_CRYCD/129-240      AC C7MML7.1
#=GS Q8XNI7_CLOPE/131-245      AC Q8XNI7.1
#=GS K8EE21_CARML/135-250      AC K8EE21.2
#=GS K0F008_9NOCA/135-248      AC K0F008.1
#=GS E2PXW4_STRC2/159-273      AC E2PXW4.1
#=GS R5QBL6_9FIRM/135-250      AC R5QBL6.1
#=GS V5X9U7_MYCNE/129-247      AC V5X9U7.1
#=GS D9QEM6_CORP2/131-245      AC D9QEM6.1
#=GS F4D0U1_PSEUX/127-240      AC F4D0U1.1
#=GS A0A0A8B5B4_9ACTN/129-240  AC A0A0A8B5B4.1
#=GS A0A076NN54_9CORY/129-251  AC A0A076NN54.1
#=GS Q65NF2_BACLD/133-240      AC Q65NF2.1
#=GS A6LZ00_CLOB8/294-382      AC A6LZ00.1
#=GS D4JW41_9FIRM/124-239      AC D4JW41.1
#=GS J7LH61_NOCAA/129-242      AC J7LH61.1
#=GS D2S430_GEOOG/129-245      AC D2S430.1
#=GS A0A0D4DSK4_9ACTN/132-251  AC A0A0D4DSK4.1
#=GS R5X1H1_9FIRM/124-239      AC R5X1H1.1
#=GS S1QXP9_9ENTE/135-251      AC S1QXP9.1
#=GS E8U4S1_DEIML/131-247      AC E8U4S1.1
#=GS A0A075JJN7_9BACI/130-242  AC A0A075JJN7.1
#=GS A9G076_SORC5/127-239      AC A9G076.1
#=GS D3F749_CONWI/135-251      AC D3F749.1
#=GS S5VK45_STRCU/131-247      AC S5VK45.1
#=GS A0A0C2Y9I8_BACBA/130-242  AC A0A0C2Y9I8.1
#=GS C0MG36_STRS7/123-235      AC C0MG36.1
#=GS A1R263_ARTAT/127-247      AC A1R263.1
#=GS Q08UK9_STIAD/1-37         AC Q08UK9.1
#=GS S0JSS9_9ENTE/135-249      AC S0JSS9.1
#=GS K0K4Z3_SACES/131-248      AC K0K4Z3.1
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V9XGI5_9NOCA/142-255                 ........................................dd----MFERYFD...KG............QIADLA....ERR.......AML.GDDVI...T....AAETS....WQELIPRVDAAL..SSG.M..DPACSEA.QEMARQWMDLLE....QFHG..-........GDEGLRDSLYRMHE......DN.AQ.............qIEQEFCGP.....S..RE....HIEFITKANE--a...........................
X4ZED4_9BACL/131-245                 ..........................................YGKEARGKYGD...EA............-VNRSN....KQL.......MNM.TEEQY...S....AVQKI....EEDMFASLAEGM..KTG.D..-SAGEAA.QRAADLHRQWLT....FFWG..S........YSPEAHAGVAQMYV......DD.ER..............FTAYYDKR.....G..AG....LARFLRDAVHAY............................
F9VGM2_LACGL/129-243                 ..........................................YGLEIRQKWGS...AR............-IDKSY....QKY.......AQA.DQAKI...Q....HWQNG....HEKMVQMLEEAY..---.E..TQDNHLA.QQAIALHKEILE....LFWP..Ea......tITPEAHIGLGQMYV......ED.PR..............FRSNYNKK.....H..AQ....LPEYFLEAIQNY............................
T0VNN2_9ENTE/135-251                 ..........................................YGEEIRAAYGE...EV............-VEQSN....QKW.......QNM.SFETY...Q....ELEQT....ENELIQTLKQVV..QEP.F..DVTSSLA.KTAFQLHKKWLQ....LAAP..F........YSADYHRSLGEMYI......HD.AR..............FTDYYDQK.....A.gQG....AASCLQAVIAHY............................
A0A0D5AG62_9NOCA/144-259             ..........................................YAEEAEQRWGE...TD............EWKQSQ....QRT.......ASF.TKDDW...K....AVKEE....TDLLEADLAAAM..QRG.V..SPESTEA.GELAERHRASIE....RYYD..-........CGYEMQVNLAEMYI......AD.ER..............FAKHYNDI.....A..DG....LAQYLRDVIVA-n...........................
D4W6R4_9FIRM/135-250                 ..........................................YGQELREKYGE...DV............-INHSN....KQF.......KNL.SKEQY...E....AMNQL....SYEILALLEEAM..-ET.N..NPESELA.QVLAKKHHEWLG....YTWP..S........YSKEAHAGLAQMYV......AD.PR..............FTAYYDEK.....I.kPG....AAQFLCDAILVY............................
A5I0A4_CLOBH/135-249                 ..........................................YSEEVKNKYGN...TS............AYKESN....EKT.......SKY.TKEDW...N....NIMKD....WDIIYKKLANLM..--D.K..NPDDKEV.QEYIHQFREHIS....KNFY..D........CTPEIFRGLGELYV......ND.ER..............FTANIDKY.....K..TG....LSKFLREAINVY............................
A0A0C5FY78_9ACTN/131-247             ..........................................YEDEVRRRWGD...TE............AYRQSR....ERT.......ASY.TKEDW...K....RVTAE....LDALHRRMAALM..DEG.L..PADSEAA.MDTAEEHRRFIT....GAYY..D........CGYEMHTCLGEMYV......GD.PR..............FTATYDAV.....R..PG....LAAWLRDAIVA-n...........................
G2NJV5_STREK/132-251                 ..........................................YATEAQLRWQH...SP............THGEAM....ARA.......SGH.SKEDW...R....RLMAE....AAAWRGELLAAF..DSA.E..PADGERA.MDIAEAHRAHLT....RWFT..P........CPPDVHRRIADDFA......AD.PRa...........faLVVPASEQ.....R..PG....LAGYLREAVHAN............................
A0A089M4I1_9BACL/125-246             ...............eqewkaalqeqgehlkesydydlmadg-----------...--............------....---.......APV.DVQHM...N....DMAAE....AAAFMTAMADAL..RSG.V..KAGDVST.VEFIRNHLDFLG....QHGH..P........MSAADFAAQNRFFL......RD.DF..............HLRMLEGQ.....Q..TG....LAYYLSAAADAF............................
C6CYX6_PAESJ/135-249                 ..........................................YGMEIREKYGD...DS............-VNASN....AKL.......SNM.TQEQY...D....EVTSL....GEEIKATLAEAF..KTG.D..-PAGELA.RKTAELHKRWLM....FYWK..E........YSKEAHAGLSQMYV......DD.ER..............FTAYYDTD.....Q..PG....VAAFLRDAIHIY............................
C6WPL5_ACTMD/131-248                 ..........................................YEAELVERFGEcvvE-............PIAEGK....ERM.......KGW.SPADA...A....GFKAE....WEEIAAAFGEVA..ASG.A..APDSAEA.LAVTARHHRWLL....RSWT..-........PNRESYTGLGQLYA......DS.PE..............FSAQLDAH.....G..AG....VANYARDAMAAF............................
R5AG95_9CLOT/124-238                 ..........................................YRDEVRERWGR...TE............EYRTAL....AKD.......AAR.SDTEN...E....AVLDG....ANAIFDAFAALV..--P.C..DPASAEA.QRLVRRWQAYIS....EHMY..P........CSKEILRGLGAMYT......AD.ER..............FRANLDAH.....G..AG....TAALMHDAIAVY............................
R5EH15_9FIRM/124-237                 ..........................................YTAEAKQKWGK...TP............AWQEFE....KK-.......-NI.TPRQA...Q....KNADD....LMDIFARFGAIR..--G.T..SPASKGA.QALVAELQGFIT....NHYY..T........CTKEILQSLGQMYI......AG.DS..............MTENIDAA.....G.gAG....TAQFAHAAIEE-f...........................
G8M2D4_CLOCD/151-275                 ......................yeeilqkafanekvasdilr--------WYR...NK............--EDFL....QAC.......KPI.QNEET...E....QLKND....SDEIFAGFAKLM..---.S..SPDTEAE.HVLVEKLADWFK....NFMK.lD........NARAVLLDFVK-EL......EN.EK..............FAEIYDSK.....Y.gKG....VSKYVSEAIMRY............................
V4KI67_9ACTN/143-256                 .........................................v---QARQRYGD...TT............QWRQYA....ERS.......ASR.TPEEW...Q....AVADD....VARLERALGEAM..DSG.V..TPGSPEA.NHLVERHREVFA....SYFP..-........LSRQMQVCLGRMYE......GD.PG..............FAAHYDAV.....R..PG....LATWFRQLVD--aa..........................
F7V2I7_CLOSS/124-239                 ..........................................YAAQAKASWGT...TP............AYKEYE....EKS.......KGR.TKEDN...L....KIHQG....MIDIFGEFGQIR..--N.T..DPASKEA.QAMVKKLQDYIT....EHMY..T........CTKEILGGLGKMYA......GG.GD..............FTTNIDKM.....G.gEG....TSAFASRAIEIY............................
A0A089Y6Y5_9LACO/1-99                ........................................mt-----------...--............------....-KA.......DQF.TDENY...N....QMKQT....EADLIRDLQAVV..KEP.E..-KEAELS.VEIFKKHQKWLQ....IIMP..N........YSPEIHLGIVSAYD......TD.TR..............YQSYYDDK.....A.gKG....ATKILSRIVK--kh..........................
H6N069_GORPV/138-253                 ..........................................YADEAQERWGD...TA............AWQQSQ....QRT.......AGY.SKDDW...R....RIKEE....TDAFEARVADAM..GRG.V..SPGSAEA.DALAEQHRAAIE....KFYD..-........CGYEMQVCLADMYV......AD.PR..............FTEHYDGV.....A..PG....LATYLREIIRAN............................
D7BZB4_STRBB/139-253                 ........................................pa---QARQRYGD...TT............QWRQYA....ERS.......ASR.GPEEW...Q....AIADA....VADLDRALGDAM..DAG.V..TPGSPEA.NQLVERHREVFA....SYFP..-........LTRQMQVCLGRTYE......AD.PG..............FAAHYDGI.....R..PG....LATWFRRIIDA-s...........................
A4FMY0_SACEN/41-132                  .....................................qeptp-----------...--............------....---.......---.-----...E....QIGRD....WNRISARIAELF..STG.V..PDNDPRT.QHAIHDHYRWIC....HFWT..-........PDRDSYLRLATLYV......SH.PK..............FRHRIERK.....K.pRG....MAAYMRDAMTAY............................
R5THD6_9CLOT/160-285                 .........................................i-AEAAVRQYGS..iENftk.....amkeNFQNYL....SEG.......PVI.SETEV...D....GIMEK....TELLTKRLTADL..--T.R..DPSSAEV.QAAVSELIAFCE....ESNR..Gi......dMGENYWLLTAEAYQ......SN.PM..............YLEVNDRK.....Y.gEG....ASKFIGSAIKEY............................
D7B301_NOCDD/143-257                 ........................................wp--RQARVVWGG...SA............QWAQFA....EQA.......AFR.TREQW...Q....SLSAS....MSALQFDLGDAL..DRG.V..VPGSPEA.DALVERHREVFS....HFFP..-........LTRRMQVCLGRMFE......SD.PG..............FSAHYDGI.....R..AG....LASWFRRSID--e...........................
T0VA61_9STRE/129-240                 ..........................................YHQEAVDKYGQ...EV............-----M....NQA.......LER.QKGRE...Y....EATRA....FNQVFQTLSQNL..KDG.L..PVSANEN.QDQAAKLLDAIR....TYGF..D........CSIEVFGHIGKGYV......YN.PE..............FKGNIDKF.....G..AG....TAQYTSDVIASY............................
#=GC seq_cons                        ..........................................atpEhpp+aGp...pt.............hppsp....p+h.......tph.sppch...p....phppp....hpplhpplspth..ttu.t..sPsuppu.pplsccappals....phah..p........sstchatsLuphYl......sD.tR..............Fpthh-ph.....t..sG....hApalpcAlth.............................
//
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