GenomeNet

Database: Pfam
Entry: TolA
LinkDB: TolA
Original site: TolA 
#=GF ID   TolA
#=GF AC   PF06519.10
#=GF DE   TolA C-terminal
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_16081 (release 10.0)
#=GF GA   20.80 20.80;
#=GF TC   20.80 20.80;
#=GF NC   20.70 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12423782
#=GF RT   The Tol proteins of Escherichia coli and their involvement in
#=GF RT   the translocation of group A colicins. 
#=GF RA   Lazzaroni JC, Dubuisson JF, Vianney A; 
#=GF RL   Biochimie 2002;84:391-397.
#=GF DR   INTERPRO; IPR014161;
#=GF DR   SCOP; 1lr0; fa;
#=GF CC   This family consists of several bacterial TolA proteins as well
#=GF CC   as two eukaryotic proteins of unknown function.  Tol proteins
#=GF CC   are involved in the translocation of group A colicins. Colicins
#=GF CC   are bacterial protein toxins, which are active against
#=GF CC   Escherichia coli and other related species (See Pfam:PF01024). 
#=GF CC   TolA is anchored to the cytoplasmic membrane by a single
#=GF CC   membrane spanning segment near the N-terminus, leaving most of
#=GF CC   the protein exposed to the periplasm [1].
#=GF SQ   251
#=GS A0A068QPS4_9GAMM/247-342  AC A0A068QPS4.1
#=GS K8WJM2_PRORE/263-360      AC K8WJM2.1
#=GS S6EBX9_AVIPA/258-353      AC S6EBX9.1
#=GS A0A071M617_9ENTR/35-128   AC A0A071M617.1
#=GS I3DNM8_HAEPH/313-409      AC I3DNM8.1
#=GS J2LS40_KLEPN/1-77         AC J2LS40.1
#=GS B1KIF7_SHEWM/209-304      AC B1KIF7.1
#=GS A0A0L0UL91_9BASI/11-105   AC A0A0L0UL91.1
#=GS E6WC32_PANSA/322-416      AC E6WC32.1
#=GS A0A0F4PJ01_9GAMM/211-306  AC A0A0F4PJ01.1
#=GS A0A068R4N5_9GAMM/252-346  AC A0A068R4N5.1
#=GS A6D8I1_9VIBR/239-337      AC A6D8I1.1
#=GS D3VAP6_XENNA/216-311      AC D3VAP6.1
#=GS I9P3P5_9ALTE/219-315      AC I9P3P5.1
#=GS Q484P7_COLP3/204-300      AC Q484P7.1
#=GS I0QT37_9GAMM/352-446      AC I0QT37.1
#=GS U3AGH0_9VIBR/243-341      AC U3AGH0.1
#=GS F4HEH4_GALAU/324-419      AC F4HEH4.1
#=GS Z5XQN4_9GAMM/213-308      AC Z5XQN4.1
#=GS H2IWI9_RAHAC/310-404      AC H2IWI9.1
#=GS G7LNP9_9GAMM/280-374      AC G7LNP9.1
#=GS H5V301_ESCHE/341-435      AC H5V301.1
#=GS A6T6G5_KLEP7/340-434      AC A6T6G5.1
#=GS Q5QYU9_IDILO/168-263      AC Q5QYU9.1
#=GS A0A0J1HI92_9GAMM/256-351  AC A0A0J1HI92.1
#=GS A3QD45_SHELP/211-306      AC A3QD45.1
#=GS E1SH23_PANVC/344-438      AC E1SH23.1
#=GS A0A089UJK1_9ENTR/19-107   AC A0A089UJK1.1
#=GS A0A0C5WLG8_9GAMM/218-313  AC A0A0C5WLG8.1
#=GS A0A0X3YD05_9GAMM/206-301  AC A0A0X3YD05.1
#=GS A8T5R3_9VIBR/240-338      AC A8T5R3.1
#=GS Q15RP0_PSEA6/199-294      AC Q15RP0.1
#=GS D4E9I2_SEROD/298-392      AC D4E9I2.1
#=GS Q7MJ86_VIBVY/254-352      AC Q7MJ86.1
#=GS U3B7A9_VIBPR/240-338      AC U3B7A9.1
#=GS Q32II2_SHIDS/325-419      AC Q32II2.1
#=GS A0A0F6TR96_9GAMM/220-313  AC A0A0F6TR96.1
#=GS A0A0H4UYF6_9COXI/161-260  AC A0A0H4UYF6.1
#=GS Q8ZQT6_SALTY/311-405      AC Q8ZQT6.1
#=GS A0A084CPB8_9GAMM/174-272  AC A0A084CPB8.1
#=GS A0A097R096_HAFAL/315-409  AC A0A097R096.1
#=GS U1JKZ1_9GAMM/214-309      AC U1JKZ1.1
#=GS E9CKW5_9GAMM/258-352      AC E9CKW5.1
#=GS F9R7W8_VIBSN/261-359      AC F9R7W8.1
#=GS L8JGN7_9GAMM/256-351      AC L8JGN7.1
#=GS A0A090RG91_9VIBR/96-195   AC A0A090RG91.1
#=GS A0A0A5HZA4_9VIBR/255-353  AC A0A0A5HZA4.1
#=GS C4LBM3_TOLAT/261-350      AC C4LBM3.1
#=GS A0KP94_AERHH/288-383      AC A0KP94.1
#=GS A0A0H2M2A4_PRORE/263-360  AC A0A0H2M2A4.1
#=GS W6IZC4_9ENTR/43-137       AC W6IZC4.1
#=GS A0A0J8YIE1_9BACT/143-237  AC A0A0J8YIE1.1
#=GS J2X088_KLEPN/30-121       AC J2X088.1
#=GS C9P3W4_VIBME/256-356      AC C9P3W4.1
#=GS A0A0W8JHZ3_9VIBR/233-332  AC A0A0W8JHZ3.1
#=GS A0A0F5AP25_9GAMM/235-330  AC A0A0F5AP25.1
#=GS R9PPN1_AGAAL/233-328      AC R9PPN1.1
#=GS A0A0D8CUV9_9GAMM/210-306  AC A0A0D8CUV9.1
#=GS F9QA34_9PAST/295-390      AC F9QA34.1
#=GS D4HXX0_ERWAC/25-114       AC D4HXX0.1
#=GS A0A0F4QFU1_9GAMM/212-309  AC A0A0F4QFU1.1
#=GS W1FRK3_ECOLX/322-416      AC W1FRK3.1
#=GS A8AJ55_CITK8/28-122       AC A8AJ55.1
#=GS A0A090V642_ESCVU/23-114   AC A0A090V642.1
#=GS I1DZ02_9GAMM/206-301      AC I1DZ02.1
#=GS Q9CM70_PASMU/291-386      AC Q9CM70.1
#=GS A0A0L7TC26_9GAMM/323-417  AC A0A0L7TC26.1
#=GS A0A014N280_9GAMM/323-417  AC A0A014N280.1
#=GS A1SSW3_PSYIN/205-300      AC A1SSW3.1
#=GS A4W888_ENT38/310-404      AC A4W888.1
#=GS K6YVP7_9ALTE/191-286      AC K6YVP7.1
#=GS A0A0F7HC92_SERFO/304-398  AC A0A0F7HC92.1
#=GS A0A0G3QE67_KLUIN/342-437  AC A0A0G3QE67.1
#=GS H2FXB8_OCESG/297-392      AC H2FXB8.1
#=GS A0A0J5S3J2_9PAST/312-407  AC A0A0J5S3J2.1
#=GS Q2NUL5_SODGM/198-292      AC Q2NUL5.1
#=GS E3BI67_9VIBR/247-346      AC E3BI67.1
#=GS A0A0T9KGF3_9GAMM/300-394  AC A0A0T9KGF3.1
#=GS D4GML8_PANAM/334-428      AC D4GML8.1
#=GS Q8EBA2_SHEON/18-117       AC Q8EBA2.1
#=GS R4I1C1_9GAMM/190-284      AC R4I1C1.1
#=GS Q9KR10_VIBCH/254-353      AC Q9KR10.1
#=GS E1SF49_PANVC/5-87         AC E1SF49.1
#=GS U3TUI0_9ENTR/281-375      AC U3TUI0.1
#=GS F7YPX0_VIBA7/254-353      AC F7YPX0.1
#=GS Q87QU0_VIBPA/254-352      AC Q87QU0.1
#=GS D2TPE1_CITRI/318-412      AC D2TPE1.1
#=GS A0A0M2VBW9_9GAMM/216-311  AC A0A0M2VBW9.1
#=GS A0A0U3B8F0_9ALTE/185-282  AC A0A0U3B8F0.1
#=GS A0A0M0IQX0_9VIBR/254-352  AC A0A0M0IQX0.1
#=GS A0A0Q0P958_9GAMM/211-306  AC A0A0Q0P958.1
#=GS A0A071LTL7_9ENTR/343-437  AC A0A071LTL7.1
#=GS W0LCR3_9GAMM/295-389      AC W0LCR3.1
#=GS Q8EDJ7_SHEON/245-340      AC Q8EDJ7.1
#=GS A0A0A7S3A1_9GAMM/228-321  AC A0A0A7S3A1.1
#=GS A0A0J8YH36_9BACT/18-100   AC A0A0J8YH36.1
#=GS L0MC65_SERMA/279-373      AC L0MC65.1
#=GS J4SM32_PASMD/1-53         AC J4SM32.1
#=GS Q7VR85_BLOFL/337-432      AC Q7VR85.1
#=GS A0A0G3CS02_9GAMM/258-352  AC A0A0G3CS02.1
#=GS A0A0F4NYI0_PSEO7/186-309  AC A0A0F4NYI0.1
#=GS M9X2T7_MANHA/308-402      AC M9X2T7.1
#=GS A0A094JBP3_9GAMM/222-317  AC A0A094JBP3.1
#=GS A0A0H2LKE8_PRORE/263-360  AC A0A0H2LKE8.1
#=GS A0A0A7EFE7_9GAMM/196-291  AC A0A0A7EFE7.1
#=GS C5BEL9_EDWI9/292-386      AC C5BEL9.1
#=GS TOLA_HAEIN/274-369        AC P44678.1
#=GS A0A0F0YGX9_9ENTR/326-420  AC A0A0F0YGX9.1
#=GS Q7N6T7_PHOLL/259-353      AC Q7N6T7.1
#=GS M4R7L5_BIBTR/301-396      AC M4R7L5.1
#=GS I2BB32_SHIBC/372-465      AC I2BB32.1
#=GS W1IW62_9GAMM/253-347      AC W1IW62.1
#=GS K8WFZ8_9GAMM/273-369      AC K8WFZ8.1
#=GS D4GL71_PANAM/47-133       AC D4GL71.1
#=GS A0A0A3APG6_9PAST/285-380  AC A0A0A3APG6.1
#=GS A0A0E3U405_9ENTR/234-327  AC A0A0E3U405.1
#=GS M1STN5_MORMO/264-358      AC M1STN5.1
#=GS E6W7V6_PANSA/19-103       AC E6W7V6.1
#=GS A0A0B8P0Y0_9VIBR/211-309  AC A0A0B8P0Y0.1
#=GS H5TBL3_9ALTE/187-282      AC H5TBL3.1
#=GS A0A0G3QDB1_KLUIN/34-127   AC A0A0G3QDB1.1
#=GS A0A0F5EWR9_AVIPA/233-328  AC A0A0F5EWR9.1
#=GS A0A090IIN8_9GAMM/266-361  AC A0A090IIN8.1
#=GS Q1ZNW6_PHOAS/289-384      AC Q1ZNW6.1
#=GS A0A0A2VY63_BEABA/460-554  AC A0A0A2VY63.1
#=GS K6YNV8_9ALTE/198-293      AC K6YNV8.1
#=GS A0A089UES4_9ENTR/343-437  AC A0A089UES4.1
#=GS D3UZV3_XENBS/231-325      AC D3UZV3.1
#=GS J5KQA3_PASMD/121-168      AC J5KQA3.1
#=GS A0A135I853_9GAMM/266-361  AC A0A135I853.1
#=GS W1E2V1_KLEPN/46-140       AC W1E2V1.1
#=GS A0A0F6AD62_9GAMM/213-308  AC A0A0F6AD62.1
#=GS C0B249_9GAMM/16-109       AC C0B249.1
#=GS C4SDY0_YERMO/285-379      AC C4SDY0.1
#=GS E0SFP4_DICD3/301-395      AC E0SFP4.1
#=GS A0A085JBT9_9GAMM/127-221  AC A0A085JBT9.1
#=GS A0A097R335_HAFAL/37-130   AC A0A097R335.1
#=GS G2H009_9ENTR/249-342      AC G2H009.1
#=GS B4ESS3_PROMH/260-353      AC B4ESS3.1
#=GS W6J2Z4_9ENTR/324-418      AC W6J2Z4.1
#=GS A0A148KNI7_9ALTE/197-292  AC A0A148KNI7.1
#=GS A0A0S2K2Y2_9GAMM/186-308  AC A0A0S2K2Y2.1
#=GS N9VKG9_9GAMM/254-349      AC N9VKG9.1
#=GS A0A0U5GJM9_9GAMM/340-434  AC A0A0U5GJM9.1
#=GS A0A014Q1J9_9GAMM/46-129   AC A0A014Q1J9.1
#=GS A0A0J8YV77_9BACT/347-441  AC A0A0J8YV77.1
#=GS X2H6N0_9GAMM/287-381      AC X2H6N0.1
#=GS D4ZJB1_SHEVD/219-314      AC D4ZJB1.1
#=GS M4U863_9GAMM/224-319      AC M4U863.1
#=GS G4QKX6_GLANF/188-282      AC G4QKX6.1
#=GS A0A085IF05_9ENTR/330-424  AC A0A085IF05.1
#=GS A0A080KFN4_9GAMM/276-370  AC A0A080KFN4.1
#=GS F7S008_9GAMM/219-314      AC F7S008.1
#=GS A0A090QR00_9GAMM/253-348  AC A0A090QR00.1
#=GS E8LJM8_9GAMM/230-317      AC E8LJM8.1
#=GS D8MPT3_ERWBE/327-421      AC D8MPT3.1
#=GS A0A0F7HDV8_SERFO/38-124   AC A0A0F7HDV8.1
#=GS A0A090P638_9VIBR/254-352  AC A0A090P638.1
#=GS A8H5P8_SHEPA/211-306      AC A8H5P8.1
#=GS A0A0J5NIV9_PLUGE/361-455  AC A0A0J5NIV9.1
#=GS B7VMJ1_VIBTL/218-316      AC B7VMJ1.1
#=GS Q6D7F3_PECAS/298-392      AC Q6D7F3.1
#=GS K2JBY5_9GAMM/211-305      AC K2JBY5.1
#=GS J4KE31_9PAST/351-447      AC J4KE31.1
#=GS A0A080KF55_9GAMM/91-185   AC A0A080KF55.1
#=GS A0A0F5V8V7_9GAMM/249-344  AC A0A0F5V8V7.1
#=GS Q65UN1_MANSM/294-389      AC Q65UN1.1
#=GS A0A1B1KPZ3_SERPL/51-144   AC A0A1B1KPZ3.1
#=GS K6YSL9_9ALTE/198-293      AC K6YSL9.1
#=GS A0A1B1KMT5_SERPL/341-435  AC A0A1B1KMT5.1
#=GS A0A0U4VYF5_9GAMM/217-312  AC A0A0U4VYF5.1
#=GS A0A099KEG3_9GAMM/230-325  AC A0A099KEG3.1
#=GS U3U369_9ENTR/20-104       AC U3U369.1
#=GS V3VA61_SERS3/287-381      AC V3VA61.1
#=GS A0A090V3Z4_ESCVU/332-426  AC A0A090V3Z4.1
#=GS A0A0N0LW43_9GAMM/209-304  AC A0A0N0LW43.1
#=GS W6J9X5_9ENTR/34-127       AC W6J9X5.1
#=GS TOLA_ECOLI/325-419        AC P19934.1
#=GS TOLA_ECOLI/325-419        DR PDB; 3QDP A; 334-419;
#=GS TOLA_ECOLI/325-419        DR PDB; 3QDR A; 329-419;
#=GS TOLA_ECOLI/325-419        DR PDB; 1TOL A; 125-211;
#=GS TOLA_ECOLI/325-419        DR PDB; 1S62 A; 4-98;
#=GS U3CDI8_9VIBR/240-338      AC U3CDI8.1
#=GS A0A0B8Q875_9VIBR/1-57     AC A0A0B8Q875.1
#=GS D4HZD2_ERWAC/296-390      AC D4HZD2.1
#=GS K0CZI4_ALTMS/191-286      AC K0CZI4.1
#=GS Q8D2E1_WIGBR/154-248      AC Q8D2E1.1
#=GS Q1Z465_9GAMM/249-344      AC Q1Z465.1
#=GS E1SLC7_FERBD/209-304      AC E1SLC7.1
#=GS A0A0M2KLM1_9GAMM/286-380  AC A0A0M2KLM1.1
#=GS K8WZN6_9GAMM/287-383      AC K8WZN6.1
#=GS A0A0E3U4P1_9ENTR/159-253  AC A0A0E3U4P1.1
#=GS E1SI03_PANVC/34-129       AC E1SI03.1
#=GS A0A085HKP0_9GAMM/236-330  AC A0A085HKP0.1
#=GS G5LL20_SALET/1-88         AC G5LL20.1
#=GS A0A0N0ZA29_9GAMM/294-389  AC A0A0N0ZA29.1
#=GS J2E7G7_KLEPN/365-459      AC J2E7G7.1
#=GS A9MJJ8_SALAR/290-384      AC A9MJJ8.1
#=GS W1J0G8_9GAMM/240-334      AC W1J0G8.1
#=GS R8AUW7_PLESH/291-386      AC R8AUW7.1
#=GS W1DE72_KLEPN/46-140       AC W1DE72.1
#=GS I3DHI6_9PAST/226-321      AC I3DHI6.1
#=GS A0A0D8QWV5_RAOPL/38-130   AC A0A0D8QWV5.1
#=GS A0A0A1B6I0_9GAMM/338-432  AC A0A0A1B6I0.1
#=GS A0A0U5L1V3_9GAMM/25-115   AC A0A0U5L1V3.1
#=GS A0A0L0H1N2_9ENTR/304-398  AC A0A0L0H1N2.1
#=GS A0A0P7WQN2_9GAMM/185-280  AC A0A0P7WQN2.1
#=GS A0A0Q4MFQ7_9GAMM/361-455  AC A0A0Q4MFQ7.1
#=GS D0YYS2_PHODD/232-327      AC D0YYS2.1
#=GS A1S7D6_SHEAM/228-323      AC A1S7D6.1
#=GS W7R089_9ALTE/200-295      AC W7R089.1
#=GS A0A0D8PLC2_9GAMM/79-174   AC A0A0D8PLC2.1
#=GS B0UVJ5_HISS2/253-348      AC B0UVJ5.1
#=GS Q0WHS2_YERPE/291-385      AC Q0WHS2.1
#=GS F5ZDH7_ALTNA/161-257      AC F5ZDH7.1
#=GS R5ELA1_9GAMM/258-347      AC R5ELA1.1
#=GS W8TZ96_YEREN/284-378      AC W8TZ96.1
#=GS Q084K2_SHEFN/220-315      AC Q084K2.1
#=GS A4CFI0_9GAMM/212-308      AC A4CFI0.1
#=GS W0HV97_9GAMM/309-403      AC W0HV97.1
#=GS A0A181D0U6_9ENTR/41-133   AC A0A181D0U6.1
#=GS A0A0S2JGT0_9GAMM/214-310  AC A0A0S2JGT0.1
#=GS A0A090SWV8_9VIBR/1-84     AC A0A090SWV8.1
#=GS A8GB92_SERP5/315-409      AC A8GB92.1
#=GS A3MZ20_ACTP2/330-426      AC A3MZ20.1
#=GS Q3IIJ5_PSEHT/202-297      AC Q3IIJ5.1
#=GS L8D845_9GAMM/209-304      AC L8D845.1
#=GS A0A097QIS4_9VIBR/255-353  AC A0A097QIS4.1
#=GS A0A0J8GRL8_9GAMM/219-314  AC A0A0J8GRL8.1
#=GS C4K8V1_HAMD5/219-313      AC C4K8V1.1
#=GS Q6LP46_PHOPR/249-344      AC Q6LP46.1
#=GS A0A0F5ZU44_9GAMM/266-361  AC A0A0F5ZU44.1
#=GS A0A080KB93_9GAMM/1-70     AC A0A080KB93.1
#=GS A0A0K2BK37_9GAMM/1-39     AC A0A0K2BK37.1
#=GS A8GDG2_SERP5/50-144       AC A8GDG2.1
#=GS A7MIW8_CROS8/315-409      AC A7MIW8.1
#=GS Q12PE7_SHEDO/228-323      AC Q12PE7.1
#=GS U4K6U7_9VIBR/250-348      AC U4K6U7.1
#=GS A0A094IWF0_9GAMM/195-290  AC A0A094IWF0.1
#=GS K2JF55_9GAMM/217-312      AC K2JF55.1
#=GS F9T1P4_9VIBR/254-352      AC F9T1P4.1
#=GS A0A0C3EAN6_9VIBR/240-338  AC A0A0C3EAN6.1
#=GS F0LQD8_VIBFN/254-354      AC F0LQD8.1
#=GS A0A136HW05_9ALTE/180-275  AC A0A136HW05.1
#=GS A0A0J8VBQ7_9GAMM/242-337  AC A0A0J8VBQ7.1
#=GS A0A094IR34_9GAMM/196-291  AC A0A094IR34.1
#=GS A0A0W1SDW0_9GAMM/161-256  AC A0A0W1SDW0.1
#=GS J3TXQ2_9ENTR/171-265      AC J3TXQ2.1
#=GS A8TC03_9VIBR/2-82         AC A8TC03.1
#=GS B8F375_HAEPS/333-428      AC B8F375.1
#=GS C9R5W0_AGGAD/301-396      AC C9R5W0.1
#=GS F7NX55_9GAMM/201-296      AC F7NX55.1
#=GS A0A090TAM6_9VIBR/239-337  AC A0A090TAM6.1
#=GS Q5E691_VIBF1/248-343      AC Q5E691.2
#=GS A0A0D8TX57_RAOPL/15-109   AC A0A0D8TX57.1
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