GenomeNet

Database: Pfam
Entry: Tox-PL-2
LinkDB: Tox-PL-2
Original site: Tox-PL-2 
#=GF ID   Tox-PL-2
#=GF AC   PF15643.2
#=GF DE   Papain fold toxin 2
#=GF AU   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L, Finn RD
#=GF SE   [1]
#=GF GA   25.00 25.00;
#=GF TC   25.80 28.10;
#=GF NC   24.60 22.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR028910;
#=GF CC   A papain fold toxin domain found in bacterial polymorphic toxin
#=GF CC   systems [1]. 
#=GF SQ   34
#=GS K9U2H9_9CYAN/5-104      AC K9U2H9.1
#=GS K9ZCE8_ANACC/7-107      AC K9ZCE8.1
#=GS K9WUF0_9NOST/7-107      AC K9WUF0.1
#=GS K9X6J1_9NOST/264-363    AC K9X6J1.1
#=GS S4Y6K4_SORCE/873-968    AC S4Y6K4.1
#=GS A9FBB8_SORC5/3042-3137  AC A9FBB8.1
#=GS L8P074_MICAE/1-41       AC L8P074.1
#=GS K9VV33_9CYAN/8-106      AC K9VV33.1
#=GS S2WPV3_9FLAO/16-111     AC S2WPV3.1
#=GS A4LGD9_BURPE/1413-1511  AC A4LGD9.1
#=GS L1P6E4_9FLAO/16-111     AC L1P6E4.1
#=GS I4FIC8_MICAE/1-41       AC I4FIC8.1
#=GS K9EMB7_9CYAN/5-100      AC K9EMB7.1
#=GS L8NYS6_MICAE/8-103      AC L8NYS6.1
#=GS A8YFQ2_MICAE/8-103      AC A8YFQ2.1
#=GS I4I061_MICAE/8-103      AC I4I061.1
#=GS K9Q7U3_9NOSO/64-169     AC K9Q7U3.1
#=GS B4W1G0_9CYAN/5-104      AC B4W1G0.1
#=GS G5IIP1_9CLOT/207-294    AC G5IIP1.1
#=GS S5NEF2_BURPE/1404-1502  AC S5NEF2.1
#=GS I4H4A3_MICAE/3-53       AC I4H4A3.1
#=GS I4HKA5_MICAE/1-59       AC I4HKA5.1
#=GS W8K3H7_BURPE/1404-1502  AC W8K3H7.1
#=GS K9QK56_NOSS7/8-103      AC K9QK56.1
#=GS B4VZQ1_9CYAN/15-113     AC B4VZQ1.1
#=GS L1NPE0_9FLAO/108-198    AC L1NPE0.1
#=GS B0JXN4_MICAN/1-71       AC B0JXN4.1
#=GS K9PTT2_9CYAN/18-116     AC K9PTT2.1
#=GS Q3ME81_ANAVT/9-109      AC Q3ME81.1
#=GS K2FYT0_9BACT/1062-1153  AC K2FYT0.1
#=GS B8HQL1_CYAP4/36-130     AC B8HQL1.1
#=GS L3QCQ3_ECOLX/39-135     AC L3QCQ3.1
#=GS B8HUB9_CYAP4/8-107      AC B8HUB9.1
#=GS A0ZN56_NODSP/16-114     AC A0ZN56.1
K9U2H9_9CYAN/5-104                 ................n-LHCQLSAIAKQ.FQ.IFECVPCAIALRQFLIEQRVFGKQISLFTGSIEDPFCNIYHERLQQN--....ISVNGRHEAISVEIDGQELIFDNIHPEGISKVDWIDNL-y..
K9ZCE8_ANACC/7-107                 ................e-QIYKLKEIIAK.YK.NLECVECAQAIQDYLVSQRISGKRLKLYTGSGIGRDSYIYDESVSGD-A....ISINGRHQGIMIIIDGVEMIFDNHHPDGVTRNQWLANL-l..
K9WUF0_9NOST/7-107                 .................EQIYQLKEIVRN.YK.NLECVECAQNIQDYLISQGVQGKRIKLYTGSAIGRNSYIYDESVSGD-A....ISVNGRHQAIAIIIDELEMIFDNHHPDGITREQWLANL-l..
K9X6J1_9NOST/264-363               ................n-NIHKITQKWNR.RT.GTNCDKCAAELEGYLREQGIPGKHIRVETTSNRGVAGIIYDDLAGKQ--....IANNGYHEGISIEINGVEIVFDDVHSEGLPRDQWLQNL-v..
S4Y6K4_SORCE/873-968               ...............aa--RAAIGTVSGSlFK.PLQCVQCASAMANALKARGIPGQVLQIRAKAGE----FIASDLVKSGTT...sITRNGYHEAVRV----GDTVFDNFFPGGVPYQTYVDSLH...
A9FBB8_SORC5/3042-3137             ................a-ARQAIGTVSGSlFK.PLQCVQCASAMANALKARGIPGQVLQIRAKAGE----FIASDLVKSGTT...sITRNGYHEAVRV----GDIVFDNFFPGGVPYQTYVDSLH...
L8P074_MICAE/1-41                  ..............mgn------------.--.----------------------------------------------DRS....ITINGKHYGVEV----RGRVFDHLSPQEMKREDWLKDFH...
K9VV33_9CYAN/8-106                 .................EIFQEIGKIIQR.FD.LYQCDACARAILQWLQANNIQGKILKLKTATRRD--GYILSWRLERQDIt.nsITQTGVHYGVEV----LGRVFDNLSVEGMTREDWLNDF-d..
S2WPV3_9FLAO/16-111                ntiekvrelvdkipded------------.KA.IFKCKDFAEKLKSLMKEAGITGKHIQIQNVIAP----NIIS---KKNGI....IGKNKFHEAIEI----DSIVFDNLETKGVKLDDWLDDI-d..
A4LGD9_BURPE/1413-1511             ...lvrqlsrdidpkfk------------.-E.IFQCKKFADELKKKMMAAGIRGDYVTVKSIEGP----LAHRDYLGGTTR....IEENGEHVLIGIKAGNETIVFDNLHPEGMEVNDWLRG--lf.
L1P6E4_9FLAO/16-111                ntiekvrelvdkipded------------.KA.IFKCKDFAEKLKSLMKEAGITGKHIQIQNVIAP----NIIS---KKNGI....IGKNKFHEAIEI----DSIVFDNLETKGVKLDDWLDDI-d..
I4FIC8_MICAE/1-41                  ................m------------.--.--------------------------------------------ENDRS....ITINEKHYGVEV----RGRVFEHLSPQEMKREDWLKDFH...
K9EMB7_9CYAN/5-100                 ................e-LFEAISTISAN.YT.VFQCVECAAAIKQWLKANNVSGIHLQIVAVGRIK---FIVSQRWHDGID...sIAQTGIHQGIET----YGKVFDNLGAEGLDRDQWVADF-d..
L8NYS6_MICAE/8-103                 ................q-IYQEIGKIVSK.FE.LYQCYECARAVMQWLTDNEIEGKVIELKTRYHDE--DYIISDRLGNDES....ITINGKHYGVEV----RGRVFDNLSPKGMIREDWLKDFH...
A8YFQ2_MICAE/8-103                 ................q-IYQEIGKIVSK.FE.LYQCYECARAVMQWLTDNEIEGKVIELKTRYHDE--DYIISDRLGNDES....ITINGKHYGVEV----RGRVFDNLSPKGMIREDWLKDFH...
I4I061_MICAE/8-103                 ...............qi--DQEIGNIVSQ.FQ.LYQCYECARAVMQWLTDNEIEGKVIELKTRYHDE--DYIISDRIGNDQS....ITINGKHYGVEV----RGRVFDNLSPQGMTRDDWLKDFH...
K9Q7U3_9NOSO/64-169                .................EVLQDITDIVNK.YP.NEYCVRCAAEIETYLKEQGIHGERIKLDTVKLRAADDFIYDNSHPPKAApeyvISTNGHHEGIAIKINGEEKVFDNHHPDGVPREQWMNNL-t..
B4W1G0_9CYAN/5-104                 .................ELRQQITKIANR.FM.IFQCQQCAEAIKQFLTELRIPAKQIKLYTGSAEDPYGNIYHEILQQT--....IATNGQHQGIAVKIGEEKLIFDNIHHQGISRKAWLNNL-y..
G5IIP1_9CLOT/207-294               ......giiakisdnlk------------.DK.VGTCDEFAKALVEKLNQAGIKFEIIRIDSRV--G----IYSDKYGSS--....IGD-KFHYGIRI----GNMVYDNLTLAGMKCEDWLADL-g..
S5NEF2_BURPE/1404-1502             ...lvrqlsrdidpkfk------------.-E.IFQCKKFADELKKKMMAAGIRGDYVTVKSIEGP----LAHRDYLGGTTR....IEENGEHVLIGIKAGNETIVFDNLHPEGMEVNDWLRG--lf.
I4H4A3_MICAE/3-53                  ....kiilsaiawgmid------------.--.----------------------------------------------QLP....ITINGKHYGVEV----RGRVFDRLSPQGIKREDWLK---ifi
I4HKA5_MICAE/1-59                  ................m------------.--.------------------------IELKTRYHDQ--DYLISDRVGNDRS....ITINGKHYGVEV----RGRVFDHLSPQGMKREDWLKDFH...
W8K3H7_BURPE/1404-1502             ...lvrqlsrdidpkfk------------.-E.IFQCKKFADELKKKMMAAGIRGDYVTVKSIEGP----LAHRDYLGGTTR....IEENGEHVLIGIKAGNETIVFDNLHPEGMEVNDWLRG--lf.
K9QK56_NOSS7/8-103                 ................e-IYQALGNISIQ.FG.NLECDKCAIALKSWSDGNGIEAKILKLRTKKRND--FFIISDRYGDSES....ITDNGIHYGVEV----LGLVFDNLSPQGLPRDEWINDF-s..
B4VZQ1_9CYAN/15-113                ................e-LYQAIGNIVVR.FP.LLHCQDCASTLKRWLKQRQIPGKLWRLSTRYDNE--DFILSQRQEQQGCf.etITENGIHYGIEV----YGKIFDNLSREGLTPDEWVKDF-t..
L1NPE0_9FLAO/108-198               .....ktrklaqtakga------------.NK.LFECKTFANDLKTKMKKEGIVGEHIEIRNTNAP----FVKS---KKNDT....IGTNYYHQGIKV----EDTIFDNLNPNGIKYDDWLDDL-e..
B0JXN4_MICAN/1-71                  ................m------------.--.------------QWLTDNEIEGKVIELKTRYHDE--DYIISDRIGNDQS....ITINGKHYGVEV----RGRVFDNLSPQGMTRDDWLKDFH...
K9PTT2_9CYAN/18-116                ................d-LEEAIGNLVVR.FP.LLHCEECARTLKRWLKQRGIPGKLWRLSTQYDNE--DFILSDRLEQQGCs.etITENGVHYGVEV----YGKIFDNLSRQGLSLEDWVQDF-t..
Q3ME81_ANAVT/9-109                 ...............dq--LRQIYTIASS.YD.NFQCVECSQAIKDYLISERISGKLIKLYTGASTGANSFIYDEAFPEE-A....ISTNGRHQGIAVIINGIETVFDNHHPAGISRDEWMANF-l..
K2FYT0_9BACT/1062-1153             ..........keiaeia------SKVTKK.YW.IFKCKECAKELSNVMTKEGIEFEKLILKWWN-----DIIYSVKKASK--....ISENWYHEATKI----WDNVFDNIHKTWIEYEEWLDDL-w..
B8HQL1_CYAP4/36-130                .................EVWQAIGELTVN.YP.VLQCYECAMAVMTYLRKKGIEGKILRLRTKHREL---FITSNRYSPSES....ITDNGIHYGVEV----FGKVFDNLSAKGLSREDWIRDF-e..
L3QCQ3_ECOLX/39-135                ...........ktrdla------TTISDK.FKqLFQCDKFAAALKSKMQQAGVNGEHLILETKNKQGAFGNIWSDRIGKN--....IATNGHHEAIKV----GDTVFDNMNPSGIKYEDWLNDI-y..
B8HUB9_CYAP4/8-107                 .................ELRQQITSIASR.FG.DFECEPCADAIEKFLRQQGISGKRIKLYTGSALGLYGNIFHDGLERN--....ISTNGRHQGVIVELDGQEIVFDNIHHEGVERTKWLLNFH...
A0ZN56_NODSP/16-114                ................k-VHSQLSAIA-E.IQ.IFECVSCAIALRQFLINQKVSGKQISLSTGTTEDPFCNIYHERLQQN--....ISINGRHEAIAVEIDGQELIFDNIHPEGISRVESINK--rs.
#=GC seq_cons                      ................t......ttl..p.ht.hhpC.cCApslpphLppptIpGchlplpottt.t...hIhs-thtpstt....IopNGhH.GlcV....tshVFDNLpPpGlp+--WLpsh....
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