GenomeNet

Database: Pfam
Entry: Tox-PL-2
LinkDB: Tox-PL-2
Original site: Tox-PL-2 
#=GF ID   Tox-PL-2
#=GF AC   PF15643.5
#=GF DE   Papain fold toxin 2
#=GF AU   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L, Finn RD
#=GF SE   [1]
#=GF GA   25.00 25.00;
#=GF TC   25.30 29.00;
#=GF NC   24.90 23.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR028910;
#=GF CC   A papain fold toxin domain found in bacterial polymorphic toxin
#=GF CC   systems [1]. 
#=GF SQ   33
#=GS A0A0D6KUN7_9CYAN/77-177   AC A0A0D6KUN7.1
#=GS K9U2H9_9CYAN/5-104        AC K9U2H9.1
#=GS A0A0K2M381_9NOST/5-104    AC A0A0K2M381.1
#=GS K9ZCE8_ANACC/7-107        AC K9ZCE8.1
#=GS K9WUF0_9NOST/7-107        AC K9WUF0.1
#=GS K9X6J1_9NOST/264-363      AC K9X6J1.1
#=GS A0A0C1Y8Y1_9CYAN/1-101    AC A0A0C1Y8Y1.1
#=GS S4Y6K4_SORCE/873-968      AC S4Y6K4.1
#=GS A9FBB8_SORC5/3042-3137    AC A9FBB8.1
#=GS A0A0A6P1H5_9GAMM/9-99     AC A0A0A6P1H5.1
#=GS K9VV33_9CYAN/8-106        AC K9VV33.1
#=GS A0A139WSE3_9CYAN/1-101    AC A0A139WSE3.1
#=GS A0A139WUX7_9CYAN/369-473  AC A0A139WUX7.1
#=GS A0A0D6L1F3_9CYAN/8-105    AC A0A0D6L1F3.1
#=GS A0A0J1GE73_9FIRM/793-880  AC A0A0J1GE73.1
#=GS A0A139X7D9_9CYAN/8-103    AC A0A139X7D9.1
#=GS A0A162RAI5_9BACT/10-76    AC A0A162RAI5.1
#=GS K9Q7U3_9NOSO/64-169       AC K9Q7U3.1
#=GS B4W1G0_9CYAN/5-104        AC B4W1G0.1
#=GS A0A0S3P6U1_9NOSO/5-104    AC A0A0S3P6U1.1
#=GS G5IIP1_9CLOT/207-294      AC G5IIP1.1
#=GS A0A0P4UU16_9CYAN/1-91     AC A0A0P4UU16.1
#=GS K9QK56_NOSS7/8-103        AC K9QK56.1
#=GS B4VZQ1_9CYAN/15-113       AC B4VZQ1.1
#=GS L1NPE0_9FLAO/108-198      AC L1NPE0.1
#=GS A0A0K2M1E5_9NOST/15-113   AC A0A0K2M1E5.1
#=GS B0JXN4_MICAN/1-71         AC B0JXN4.1
#=GS K9PTT2_9CYAN/18-116       AC K9PTT2.1
#=GS A0A0K2M5X1_9NOST/6-105    AC A0A0K2M5X1.1
#=GS A0A0C1NG96_9CYAN/216-316  AC A0A0C1NG96.1
#=GS B8HQL1_CYAP4/36-130       AC B8HQL1.1
#=GS B8HUB9_CYAP4/8-107        AC B8HUB9.1
#=GS A0ZN56_NODSP/16-114       AC A0ZN56.1
A0A0D6KUN7_9CYAN/77-177              .........................e-KIHQIKEIIRK.Y.KNLECVECAQAMQDYLISQGI..SGKRIKLYTGSAIGRNSYIYDDSLSGD-A....ISLNGRHQCIAIIINEVEIIFDNHHPDGLTREQWLGNL-q.
K9U2H9_9CYAN/5-104                   .........................n-LHCQLSAIAKQ.F.QIFECVPCAIALRQFLIEQRV..FGKQISLFTGSIEDPFCNIYHERLQQN--....ISVNGRHEAISVEIDGQELIFDNIHPEGISKVDWIDNL-y.
A0A0K2M381_9NOST/5-104               .........................d-IVRQLNDIAEQ.F.HIFECVPCAIALRQFLINQKI..PGREINLFTGSTEDPFCNIYHEVLQQN--....ISINGRHYAIAIEINGQELIFDNIHPEGISRVNWINNL-y.
K9ZCE8_ANACC/7-107                   .........................e-QIYKLKEIIAK.Y.KNLECVECAQAIQDYLVSQRI..SGKRLKLYTGSGIGRDSYIYDESVSGD-A....ISINGRHQGIMIIIDGVEMIFDNHHPDGVTRNQWLANL-l.
K9WUF0_9NOST/7-107                   ..........................EQIYQLKEIVRN.Y.KNLECVECAQNIQDYLISQGV..QGKRIKLYTGSAIGRNSYIYDESVSGD-A....ISVNGRHQAIAIIIDELEMIFDNHHPDGITREQWLANL-l.
K9X6J1_9NOST/264-363                 .........................n-NIHKITQKWNR.R.TGTNCDKCAAELEGYLREQGI..PGKHIRVETTSNRGVAGIIYDDLAGKQ--....IANNGYHEGISIEINGVEIVFDDVHSEGLPRDQWLQNL-v.
A0A0C1Y8Y1_9CYAN/1-101               ........................mr-------DIVSP.H.ENFQCVPCAGEIEAYLKEQGI..HGERIKLDTVKQVDQDSLIYDDSNPPKAApdyiISTNGHHEGIAIRINGEEKVFDNLHPDGVPREQWMNNL-t.
S4Y6K4_SORCE/873-968                 ........................aa--RAAIGTVSGSlF.KPLQCVQCASAMANALKARGI..PGQVLQIRAKAGE----FIASDLVKSGTT...sITRNGYHEAVRV----GDTVFDNFFPGGVPYQTYVDSLH..
A9FBB8_SORC5/3042-3137               .........................a-ARQAIGTVSGSlF.KPLQCVQCASAMANALKARGI..PGQVLQIRAKAGE----FIASDLVKSGTT...sITRNGYHEAVRV----GDIVFDNFFPGGVPYQTYVDSLH..
A0A0A6P1H5_9GAMM/9-99                ...................aiilvdk--------VPKK.YhELYQCEQFANTLIELLKEKGI..HGEYLNVTSST-----PFLYSDSLGKP--....ITTNGKHYAVNV----GHKVFDNLNPKGISYQEWENDL-g.
K9VV33_9CYAN/8-106                   ..........................EIFQEIGKIIQR.F.DLYQCDACARAILQWLQANNI..QGKILKLKTATRRD--GYILSWRLERQDIt.nsITQTGVHYGVEV----LGRVFDNLSVEGMTREDWLNDF-d.
A0A139WSE3_9CYAN/1-101               .......................msd-----IVNSFKP.N.NNLKCVECAQKIEDYLKEKNI..RGERVELNTPRLTPYDDNIYDDSLPQGSD...aISENGHHRGIEITVNGERKVFDNHHPDGVPTEQWKNNL-v.
A0A139WUX7_9CYAN/369-473             .........................q-VLQDVYNIANK.Y.PNTKCVDCANEIEKYLKTKNI..RGRRVVLDTPKSEPRNFNVYDDSLPPKSDg.gvIADNGHHEGIAIRINGEEKVFDNHHPDGVPTEQWKNNL-t.
A0A0D6L1F3_9CYAN/8-105               ..........................EIYQAIGRIVAN.F.GLYQCNECANAVMHWLQKNNI..KGRIIKIQTAFGED---YIISTRLENQGIt.dsITLNGIHYGVEV----KDRIFDNLSTQGLTVNDWRNDF-e.
A0A0J1GE73_9FIRM/793-880             ................yndidedgyg------------.-.---KCKVAADEMVEYLKKNKQ..NGAVINLMWSPRDS--GYIWSDYAGKV--....AGDNGLHVGVLY----EGRVYCNVHPYGLPKQQWIDDF-n.
A0A139X7D9_9CYAN/8-103               .........................e-IYQALGNISSQ.F.KNLECDKCAIALKSWSDSNGI..EGKIIKLRTKKRND--FFIISNRYSDSES....ITDNGIHYGVEV----FGLVFDNLSRQGLPRDEWINDF-s.
A0A162RAI5_9BACT/10-76               ivkgaggevrifeinigkngligtpt------------.-.---------------------..---------------------------KQ....LADNGMHRYVEVSIGNEVRIYDNFHPDGILKNDYIKE--ig
K9Q7U3_9NOSO/64-169                  ..........................EVLQDITDIVNK.Y.PNEYCVRCAAEIETYLKEQGI..HGERIKLDTVKLRAADDFIYDNSHPPKAApeyvISTNGHHEGIAIKINGEEKVFDNHHPDGVPREQWMNNL-t.
B4W1G0_9CYAN/5-104                   ..........................ELRQQITKIANR.F.MIFQCQQCAEAIKQFLTELRI..PAKQIKLYTGSAEDPYGNIYHEILQQT--....IATNGQHQGIAVKIGEEKLIFDNIHHQGISRKAWLNNL-y.
A0A0S3P6U1_9NOSO/5-104               ..........................ELRQQITEIASS.F.HLFEWVECANAIRQFLTTQNV..PGKIIRLSTDSTKEPFCNIYHELLQEN--....ISANGRHEAIAVKIAGQELIFANIHPVGISKVNWMNNL-y.
G5IIP1_9CLOT/207-294                 ...............giiakisdnlk------------.D.KVGTCDEFAKALVEKLNQAGI..KFEIIRIDSRV--G----IYSDKYGSS--....IGD-KFHYGIRI----GNMVYDNLTLAGMKCEDWLADL-g.
A0A0P4UU16_9CYAN/1-91                ........................ml-------QIASE.F.PLLSCEQCARAMMQWLTANQI..QGKISKLKTKRRGE--AFISSDRFDPNQS....ITENGTHYGVEV----LGQVFDNLSTVGLTRQDWLQDFH..
K9QK56_NOSS7/8-103                   .........................e-IYQALGNISIQ.F.GNLECDKCAIALKSWSDGNGI..EAKILKLRTKKRND--FFIISDRYGDSES....ITDNGIHYGVEV----LGLVFDNLSPQGLPRDEWINDF-s.
B4VZQ1_9CYAN/15-113                  .........................e-LYQAIGNIVVR.F.PLLHCQDCASTLKRWLKQRQI..PGKLWRLSTRYDNE--DFILSQRQEQQGCf.etITENGIHYGIEV----YGKIFDNLSREGLTPDEWVKDF-t.
L1NPE0_9FLAO/108-198                 ..............ktrklaqtakga------------.N.KLFECKTFANDLKTKMKKEGI..VGEHIEIRNTNAP----FVKS---KKNDT....IGTNYYHQGIKV----EDTIFDNLNPNGIKYDDWLDDL-e.
A0A0K2M1E5_9NOST/15-113              ..........................EIHQAIGNLVIR.F.PLLHCQECAKTLKQWLKQRKI..PGKVWRLSTIYDNE--DFILSNRLEKQGCf.etITENGVHYGVEV----FGKIFDNLSRQGLYPDDWIQDF-t.
B0JXN4_MICAN/1-71                    .........................m------------.-.-------------QWLTDNEI..EGKVIELKTRYHDE--DYIISDRIGNDQS....ITINGKHYGVEV----RGRVFDNLSPQGMTRDDWLKDFH..
K9PTT2_9CYAN/18-116                  .........................d-LEEAIGNLVVR.F.PLLHCEECARTLKRWLKQRGI..PGKLWRLSTQYDNE--DFILSDRLEQQGCs.etITENGVHYGVEV----YGKIFDNLSRQGLSLEDWVQDF-t.
A0A0K2M5X1_9NOST/6-105               ........................ii--YQQIIAIASS.Y.GIFDCIPCARAIKEFLIRQSI..HGKHIKINTNSQDPIYGRIYDDSIGEL--....IATTGHHEGVIIEINDGELVFDNIHHQGITRLNWIQNL-y.
A0A0C1NG96_9CYAN/216-316             ........................lp----EIKKITGRaN.RIGGCDVLAGQIENYFIKEGIpqSGRHIRLETGFNTGEGAYIVDRTTGDV--....IGTAGYHEGIIVNIDGQEVVFDNLNPNGQLKEAWLQRF-y.
B8HQL1_CYAP4/36-130                  ..........................EVWQAIGELTVN.Y.PVLQCYECAMAVMTYLRKKGI..EGKILRLRTKHREL---FITSNRYSPSES....ITDNGIHYGVEV----FGKVFDNLSAKGLSREDWIRDF-e.
B8HUB9_CYAP4/8-107                   ..........................ELRQQITSIASR.F.GDFECEPCADAIEKFLRQQGI..SGKRIKLYTGSALGLYGNIFHDGLERN--....ISTNGRHQGVIVELDGQEIVFDNIHHEGVERTKWLLNFH..
A0ZN56_NODSP/16-114                  .........................k-VHSQLSAIA-E.I.QIFECVSCAIALRQFLINQKV..SGKQISLSTGTTEDPFCNIYHERLQQN--....ISINGRHEAIAVEIDGQELIFDNIHPEGISRVESINK--rs
#=GC seq_cons                        .........................t..hptltpIstp.a.t.hpCspCApslppaLpppsI..pG+hl+LpTsptps..saIhs-plpps......IopNGhH.GltV....tchlFDNlpPpGls+ppWlssh.h.
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