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Database: Pfam
Entry: Toxin_10
LinkDB: Toxin_10
Original site: Toxin_10 
#=GF ID   Toxin_10
#=GF AC   PF05431.10
#=GF DE   Insecticidal Crystal Toxin, P42 
#=GF PI   Toxin_P42; Toxin_10; Toxin_10_; Toxin_10; Toxin_P42;
#=GF AU   Finn RD
#=GF SE   Pfam-B_19338 (release 8.0)
#=GF GA   28.60 28.60;
#=GF TC   29.20 28.80;
#=GF NC   28.40 28.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   9500937
#=GF RT   Variants of the Bacillus sphaericus binary toxins: implications
#=GF RT   for differential toxicity of strains. 
#=GF RA   Humphreys MJ, Berry C; 
#=GF RL   J Invertebr Pathol 1998;71:184-185.
#=GF DR   INTERPRO; IPR008872;
#=GF CC   Family of Bacillus insecticidal crystal toxins.  Strains of
#=GF CC   Bacillus that have this insecticidal activity use a binary toxin
#=GF CC   comprised of two proteins, P51 and P42 (this family).  Members
#=GF CC   of this family are highly conserved  between strains of
#=GF CC   different serotypes and phage groups [1].
#=GF SQ   26
#=GS A0A124HDY9_9ACTN/206-373  AC A0A124HDY9.1
#=GS M7TX19_BOTF1/243-393      AC M7TX19.1
#=GS B8HJ33_PSECP/267-422      AC B8HJ33.1
#=GS A0A164I1L2_9NOCA/243-392  AC A0A164I1L2.1
#=GS V6JGH6_STRRC/193-359      AC V6JGH6.1
#=GS A0A0F4JLZ2_9ACTN/1-161    AC A0A0F4JLZ2.1
#=GS A0A0S8H436_9BACT/447-617  AC A0A0S8H436.1
#=GS A0A0A0KQZ6_CUCSA/209-375  AC A0A0A0KQZ6.1
#=GS D9VKZ2_9ACTN/251-416      AC D9VKZ2.1
#=GS A0A0B4GZD8_9HYPO/242-393  AC A0A0B4GZD8.1
#=GS K9PFX5_9CYAN/196-378      AC K9PFX5.1
#=GS A0A0D6YNA6_MASLA/234-399  AC A0A0D6YNA6.1
#=GS A0A101NTF4_9ACTN/124-286  AC A0A101NTF4.1
#=GS E2Q428_STRC2/249-399      AC E2Q428.1
#=GS E2PY35_STRC2/276-423      AC E2PY35.1
#=GS A0A0L1HIN4_9PLEO/229-380  AC A0A0L1HIN4.1
#=GS E4ZP30_LEPMJ/237-392      AC E4ZP30.1
#=GS U9W0P1_9CYAN/171-342      AC U9W0P1.1
#=GS A0A0M9ZJZ9_9ACTN/192-359  AC A0A0M9ZJZ9.1
#=GS A0A194WTD1_9HELO/231-376  AC A0A194WTD1.1
#=GS A0A177D8V2_ALTAL/240-391  AC A0A177D8V2.1
#=GS E3RCD1_PYRTT/33-171       AC E3RCD1.1
#=GS A0A0D4DF32_9ACTN/216-375  AC A0A0D4DF32.1
#=GS Q0RIN8_FRAAA/263-410      AC Q0RIN8.1
#=GS A1BGH9_CHLPD/208-393      AC A1BGH9.1
#=GS A0A0A0KR20_CUCSA/94-269   AC A0A0A0KR20.1
A0A124HDY9_9ACTN/206-373             ..................ve--VGAMAYPFPLV.RDPAYD.....RRRQAQDNPYYILRR.YGFWERV....Y.SYEH..GGASDYTHTEETTVGLTTTNARTVEETTSISVTAEA..........SFGFKGVGA................S.L..STTISHELKVTT..THEEVKSHSK.KVTIER.NYQA-GKRVTEAIWYRSDKYVLERLNGTVVLD.WTTRDPNTSVADAYP-l.......................................
M7TX19_BOTF1/243-393                 vtlplrcffwsedarcltqi-------------.------.....------AKPFITISK.GIAWYVE....G.VWEN..GGEGTFTREKRIKCGISQTQTESMEHTVGISITASH..........GFKFAEMSV................T.L..NYQF------TH..TRSTSFTEFT.ETEVVE.SFEV--P-------------------------.----------------aktctvlfskhiylkgsmnnggtvmnqieavanddv....
B8HJ33_PSECP/267-422                 paavlpctvvtdpnensspl-------------.------.....------TDPFYYLAS.EPYW--D....C.FQRL..PSEKATHWSRQVSVGTTTTDSNTFQRTSSLTVGAET..........GVEAEGLSA................K.V..SVSFTDEMQVSV..YHADEKSSLQ.VTTADI.DLPT---AKMVFVWLERTNIVLYRTEGSPDTG.AEVAN-----------avlfekas................................
A0A164I1L2_9NOCA/243-392             ..................rv-----VTVPCTVV.TDPGKT.....IAWQVANSPFYTLQR.RVNYSLQ....I.FRNN.qNGSTPAESSVSVTTGVTETASEEFSKRTSVTVTAKA..........GIEVKGLSA................G.V..ETSVTTELGYSS..----RYEVAQ.LRS---.--------------------------------.----------------vtkthglttppqasgalwsatheiiairrdgeaigggs..
V6JGH6_STRRC/193-359                 ....................VLIGQLAVPFFTI.GDSS--.....PQWQVDNSPYYILKR.YGYWQKV....F.FYEH..PGTSKVTKTKKVTVGLTTSTGKTVEETTGISVTAEA..........SFAYKGFSA................S.L..STTYSRELKVTT..YTGEVHEHST.EETIER.EYQADGVRVAECLWYRGDRYTVERMDGTKVLE.WNTLNPAVEVLDGYR-g.......................................
A0A0F4JLZ2_9ACTN/1-161               ....................MLVGSVLFPFPFI.NDPVLS.....RARQGQENPYYVLKR.YGSWRNV....Y.YYEH..SGASAYTKEEEVTVGVTTSNTKEVEHTAGVKLTATS..........EFSFIGAST................T.L..SV-------VST..TTTSTSENTR.KTTVRR.EYPA-GPRRAEAIWYREDRFVLERLNGEHVLE.WAVRNPDRVITDAYPA........................................
A0A0S8H436_9BACT/447-617             ...............vgtkt-----MLVPFTALlGGTDFGg..adVHWMVHNSPTVQVER.VIYNHLM....Y.HGIN..NTSVVQENLLEFVSGVSTTDSETFSHTAGISITVES..........GVEFFGSGG................S.V..SVTASYEFGYES..MHSVTA--LR.EKHIVV.TIYT-VPGKAAAAWQQRNAYRVKRHRGTE---.----------------ldvvgelefgmdsyvvdeyp....................
A0A0A0KQZ6_CUCSA/209-375             ....................IVVGKWYCPFIFV.REGD--.....VDSQIKNSPYYEMTL.QQNWVEV....F.GCGN.nSGGRGVELDVLVEKEVVSVAGRVV---AGVNIGDGAa.......wfGSSRVGLSM................A.IveRIKWEEEKGGFE..WVREGGEKEV.KVKRRE.EFEGVGMWRRFGCYVLVERFELRRMDGTLVLS.WEFRH-----------tnqirtkw................................
D9VKZ2_9ACTN/251-416                 ..................tt--VNAVWVPFMAV.KDDDKS.....ASWKLTNSPFYRIER.RASWFMH....R.FINN..TTSTAQSVSETVTVGVERERSDTFSAEVGISVSSQV..........GVSSGIASA................S.V..TTTYSLALGYSS..STATKNLE--.HKAVTH.TLTA-PPNKAAAMWVGDHTIQVTRQDGTHVGT.----------------pltfhgdsahfdefpd........................
A0A0B4GZD8_9HYPO/242-393             ................ckat-------LPFHFF.FPPNHQ.....DSLDNIHNPFLTVSR.TIAWYVE....G.VWVN..DGEGDYSRQQRILYGVSKEQREEMTHTVGVEISATY..........GIKLSSVSV................T.L..NYQFTH--TSST..SLTEYSEREV.TETINV.PKHSASVLFTKHVWIKV---------------.----------------yrldspvvlqqmemtandd.....................
K9PFX5_9CYAN/196-378                 ................vgkp-----FLLPYFMV.NDNN--.....PAWQVQNSPYYLLSR.EVCYTLN....D.QYFTynNTASEQEYEVTIRAGFTTEESENFSKTTGLEVANTLeqtigakvgaE-------TkipgfgkvsgevssetS.F..SLTASASLSLGY..STSTSLSRHN.EQEIRR.LVKC-QPYTSLAGWTQTSRFTLLRLDGSRLKT.WEVLEG----------gvfiddi.................................
A0A0D6YNA6_MASLA/234-399             ................lany-----VWIPCFSV.KDDQYD.....LSWKVNNSPFYRLDR.EEFYTLQ....W.HFFN..NTEATDSKQKSVKVGITQTDSQSFSTQTGISITAEA..........SAGIEGIAS...............tK.I..SATYS--VQLGF..ESSSSFTQMK.EDTITD.TYNI-PPYKAVALWTKTNRFTLKRADGLAVGNsWEIQT-NSTVKDQYP-d.......................................
A0A101NTF4_9ACTN/124-286             ..................ri-----VRVPFTGV.NDEGRD.....LQWKVLNSPFYRLHRrVGYNRAI....F.TNNQ..HGTQPARASEQVVTGVVQSESEAWTTLTRIVVSASA..........GIAFKGLSV................G.A..DVNITRETGYEK..RTS--LTEFT.ESTRTQ.EMVT-PPQASGVLWVKSHELQLYRVDGSAVAE.----------------alsfqfpsyaianyp.........................
E2Q428_STRC2/249-399                 .................dht-----VIVPCSVV.KDVGLT.....AGQQVDQTPFYTLER.RVSYYCQ....M.HYDN.tTGPVQQTNEQTVTTGVSKTKSEEFSTRTSIGISRTA..........GISMQGMEA................S.Q..TLNFSIEFGYSVryDNTQFEENSN.KWSL--.--------------------------------.----------------svppktaaslwsprheiialrddgtavggqg.........
E2PY35_STRC2/276-423                 ..................dy----SVVVPFTGI.TDTELS.....LTQKTDGSAFYTVER.QNRYHLV....D.FGTN.tSNTDNPGNTRQVSVGISDSQSSTFTQTYGLEVGYER..........GIGLKPELS................T.I..HFNLSTQLGYAT..TTQVSVMVTE.T-----.--------------------------------.----------------ltqgmplpaqssaalwagshricprradgtyid.......
A0A0L1HIN4_9PLEO/229-380             ..................qc----EVVLPFTVF.FPSTDR.....ACLQQISRPFCRLAR.TTAWYVH....A.THSN..NSGGEISDKTTVTRGVSKTESTEMAHSAGVKISASY..........GISGFGMGV................S.L..NYQFT--STTTS..SYNEYTESSR.EQGFTV.--------------------------------.----------------ppyhatvflvrhvwlkatrsdgtavlretgfnand.....
E4ZP30_LEPMJ/237-392                 ..................re-----VKLPFICL.FPPTDR.....PSIDRIDNPFCSIQR.WGSWSLS....M.WDDN..TTSRDQDSSTSTTVGVSDSQSEEFSHSAGIKITSGA..........GISVGVFNA................S.G..SY--ELNYQFTY..TSSTSRELLS.SKTVTR.NLKT-PPGKACALWVRHFVFRSVRADGSNI--.----------------gydlpfdvnvf.............................
U9W0P1_9CYAN/171-342                 ...................k-LIGEALIPAVFV.NDTAYS....dHRYQILQNPYYVLRR.EQYWDRSqgrgI.YYQH..DGQREVEKTFSIEFGISEKTSQKIEDTFGWKLSASG..........KFGFDKSSI................A.L..AGSLSRSIKTTT..TNETEIKASK.KETYKE.KISE--KKFAYAQYALVDHYRLFDKHKNVVRE.WEIVLYKTTMSDGFD-a.......................................
A0A0M9ZJZ9_9ACTN/192-359             ....................VLIGQTAVPFA-V.QDGGGS.....AGDQSQNNPYLVIKR.YGYWEQV....F.FYEH..AGNSEHEEVKETTVGLTKTSATEVERFTGISVTAEA..........SFAYKGFSA................G.L..SSTVTSSLKTTY..SSSETHEHWV.KDTIRR.TYANNGRRVSEALWYRGDKYVAQRMDGSPVVE.WETRTKEFSVLDGWP-q.......................................
A0A194WTD1_9HELO/231-376             ..................dr----SVVIPFTCV.FPANDQ.....TSVDLIFNPFISIEQ.WGNWTLA....L.FDNN..TVSVKQSSSQEITTGITNSQTETFEHSTGVKISAEV..........GVELVGKVT................TeL..YY--Q----FTY..TTSASTETLR.SQTITH.TLTT-PPQHAAALWVKHLAYRAVRL-------.----------------adgsiigq................................
A0A177D8V2_ALTAL/240-391             avtlpftaffpptdksclnl-------------.------.....-----ISHPFITLQR.RTAWYVE....D.VARN..AADQSGTHSTKITKGVSASQSQEMTHSAGVSITSSF..........GIKAIGGGV................D.V..TLNYQFTASQSY..SSSEYQETEK.THTFNI.GPQTVLVLLTDRVWIQA---------------.----------------trsdgsatlhrigynatd......................
E3RCD1_PYRTT/33-171                  ..................qa----QLTLPFTAI.FSPTDR.....SCLDNISDPFVTLSK.RSAWIVA....S.AHVN..DSRGQITVKTTVTRGISKSQAEEITNSAGVEVSASY..........GI--GGFSM................G.V..SLNYQFTSTKSS..SYTEYQESTR.EQTYTIpEYHA-TVFFIRHMWLKA---------------.----------------hrsng...................................
A0A0D4DF32_9ACTN/216-375             ..................ri-----VTVPCTAI.IDKGQS.....PEWIVKNSPVYTVQR.ERLYDLV....VsLYNQ..TDVEDEI-GNDVTEGVTTTDSKAFHETVGMKVGFEV..........GIQAEGIGA................K.V..SGEISKEMGYSQ..EHSVSV--MQ.ENSVHA.TAKA-APKKTTALYSETHTLRAYRMDGTQASQ.QNGL------------tfhagkqya...............................
Q0RIN8_FRAAA/263-410                 ..................ra-----VIVPCTLV.KDPNKT.....IAWQVANSPFYTLER.RVNYTLQ....I.FRNN.eAGTVPQPSNRRVTTGVSKERSEEYSRKTSVTVSASA..........GISIKAFSA................S.I..DTSVTTELGYSS..RYGVT-----.------.--------------------------------.----------------qftedskdhglitpprssgalwsatheviairkdgdavgg
A1BGH9_CHLPD/208-393                 ....................VFVGETLIPFYMV.GSDSACvgnnlRSWQINNRPYYCLKR.EQQWRLD....P.KGIInqPDIAHRTEKIKVSSGIEQQSGTVMQKKTGFSVGMDFgnk....semGVTFDGITAkte..........ttrA.F..KIQWQNEVTITT..TESTKIWETT.ERELII.DYETVSGGFTYIYWVLTDIWTL--LSGEDTSDsWEVMT-VLSQPTTFPK........................................
A0A0A0KR20_CUCSA/94-269              ....................VVVGKWYCPFIFI.REGE--.....VGAQMRDSAYYEMTL.QQNWEEI....H.GCYN..DDDNNYDNNGHVAVDVSVRRETVLV--GGVSMATKRva.....vsdGVMWFGATLelgl........smaiV.E..RMKWEEE-RVGF..VWGKSNEDGEiERVVRReEFKGKGMWKRFRCYVLVERFVLERMNGTLVLT.WEFRQT----------hrirtkw.................................
#=GC seq_cons                        ..................ph.....hhlPFhhl.t-ss.p.....hshphtssPaYplpR.pstWpht....h.hhpN..sussshspsppVosGlopopocphpcosGlsloups..........GlphtGhus................u.l..shshohphthop..spupptpphp.cpolph.phps.s.hhs.thWhtt..h.h.chpt......................s...t...................................
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