GenomeNet

Database: Pfam
Entry: Toxin_4
LinkDB: Toxin_4
Original site: Toxin_4 
#=GF ID   Toxin_4
#=GF AC   PF00706.12
#=GF DE   Anenome neurotoxin
#=GF PI   toxin_4; 
#=GF AU   Bateman A
#=GF SE   Pfam-B_589 (release 2.1)
#=GF GA   20.90 20.90;
#=GF TC   21.80 21.60;
#=GF NC   18.00 20.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Sea_anemone_neurotoxin
#=GF DR   INTERPRO; IPR000693;
#=GF DR   SCOP; 1atx; fa;
#=GF DR   HOMSTRAD; seatoxin;
#=GF SQ   75
#=GS TX281_NEMVE/41-83   AC B1NWR6.2
#=GS TX2_BUNGR/3-46      AC P0C1F4.1
#=GS TXAE1_ACTEQ/31-80   AC Q9NJQ2.1
#=GS TXH16_ANTS7/3-45    AC P0C5F7.1
#=GS TXH8_ANTS7/3-45     AC P0C5F6.1
#=GS TXA12_ANTEL/3-45    AC P0C1F1.1
#=GS TXC3_BUNCI/3-46     AC Q7M425.1
#=GS TX451_NEMVE/41-83   AC B1NWR7.1
#=GS TXCAN_BUNCN/3-46    AC P82803.1
#=GS TX1_ANTXA/3-45      AC P0C5F8.1
#=GS TXA1_ANTFU/3-45     AC P10453.1
#=GS TX371_NEMVE/41-83   AC P0CH90.1
#=GS B1NWU2_ACTEQ/31-80  AC B1NWU2.1
#=GS TXA4_HETCR/2-44     AC P30784.1
#=GS TX171_NEMVE/41-83   AC P0CH45.1
#=GS TX271_NEMVE/41-83   AC B1NWS1.2
#=GS TXCL1_CALPA/35-76   AC P14531.2
#=GS TXA22_ANTEL/3-45    AC P0C1F3.1
#=GS TXD1A_BUNCN/3-45    AC P86459.1
#=GS B1NWT7_9CNID/35-77  AC B1NWT7.1
#=GS TXH7_ANTS7/3-45     AC P0C5F5.1
#=GS TXRC1_HETCR/3-45    AC P0C5G5.1
#=GS TXA2_HETCR/2-44     AC P30783.1
#=GS B1NWR3_9CNID/36-78  AC B1NWR3.1
#=GS B1NWU4_ACTEQ/31-80  AC B1NWU4.1
#=GS TXCN2_BUNCN/3-46    AC P0C7P9.1
#=GS B1NWU6_ACTEQ/30-79  AC B1NWU6.1
#=GS DETXX_HETHE/37-79   AC D2KX91.1
#=GS TXA3_HETCR/2-44     AC P30832.1
#=GS TXAC_ANTEL/3-45     AC P01532.1
#=GS TX391_NEMVE/41-83   AC P0CH46.1
#=GS TX3_BUNGR/3-46      AC P0C1F5.1
#=GS B1NWU1_ACTEQ/31-80  AC B1NWU1.1
#=GS DETX1_CRYAD/37-79   AC D2KX90.1
#=GS TXNA_CONGI/3-45     AC P0C280.1
#=GS TXNA_CONGI/3-45     DR PDB; 2H9X A; 3-45;
#=GS TXD1B_BUNCN/3-45    AC P86460.1
#=GS B1NWU5_ACTEQ/31-80  AC B1NWU5.1
#=GS TXAA_ANTXA/3-47     AC P01530.1
#=GS TXAA_ANTXA/3-47     DR PDB; 1AHL A; 3-47;
#=GS SHTX4_STIHA/37-79   AC B1B5I9.1
#=GS B1NWT5_9CNID/39-80  AC B1NWT5.1
#=GS TX5_ANTXA/3-45      AC P0C5G2.1
#=GS TXA1_HETCR/2-44     AC P30831.1
#=GS TXA2_RADPA/2-44     AC P01534.1
#=GS B1NWT3_9CNID/37-70  AC B1NWT3.1
#=GS TXA5_HETCR/2-44     AC P30785.1
#=GS D0VLT9_URTCR/36-77  AC D0VLT9.1
#=GS TXAB_ANTXA/3-47     AC P01531.1
#=GS TXAB_ANTXA/3-47     DR PDB; 1APF A; 3-47;
#=GS DETX1_THAAS/37-79   AC D2KX92.1
#=GS TX251_NEMVE/41-83   AC B1NWS4.2
#=GS TXAM3_ANTMC/29-71   AC P69928.1
#=GS TX7_ANTXA/3-47      AC P0C5G4.1
#=GS TXH2_ANTS7/3-45     AC P0C5F4.1
#=GS TX3_ANTXA/3-45      AC P0C5G0.1
#=GS TXA1_STOHE/2-44     AC P19651.1
#=GS TXA1_STOHE/2-44     DR PDB; 1SHI A; 2-44;
#=GS TXA1_STOHE/2-44     DR PDB; 1SH1 A; 2-44;
#=GS TXA1_STOHE/2-44     DR PDB; 2SH1 A; 2-44;
#=GS GIG3_STIGI/37-79    AC Q76CA0.1
#=GS B1NWU3_ACTEQ/31-80  AC B1NWU3.1
#=GS TXCP1_CONPS/3-45    AC P0CH42.1
#=GS TXA2_ANTFU/4-46     AC P10454.1
#=GS TXA5_ANESU/3-45     AC P01529.1
#=GS AETX1_ANEER/3-44    AC P69943.1
#=GS TX2_ANTXA/3-45      AC P0C5F9.1
#=GS TXCL2_CALPA/35-76   AC P49127.1
#=GS TXA3_RADPA/2-44     AC P08380.1
#=GS B1NWR0_9CNID/36-78  AC B1NWR0.1
#=GS TXA21_ANTEL/3-45    AC P0C1F2.1
#=GS HAL_HALCG/2-44      AC P0C5G6.1
#=GS TX4_ANTXA/3-45      AC P0C5G1.1
#=GS TX401_NEMVE/41-83   AC B1NWS8.1
#=GS GIG2_STIGI/33-72    AC Q76CA3.1
#=GS TXA1_ANESU/3-44     AC P01533.1
#=GS TXA1_ANESU/3-44     DR PDB; 1ATX A; 3-44;
#=GS TXA2_ANESU/3-45     AC P01528.1
#=GS TXCN3_BUNCN/3-46    AC P0C7Q0.1
#=GS TX6_ANTXA/3-47      AC P0C5G3.1
#=GS TXA11_ANTEL/3-45    AC P0C1F0.1
#=GS TX411_NEMVE/41-83   AC A7SCE5.2
TX281_NEMVE/41-83              .PCACDSDGPDIRSASLSGIV..WM.......GSC...PSGWKKCKSYYSIVADCC
TX2_BUNGR/3-46                 .SCRCDSDGPTSRGNTLTGTL..WL......iGRC...PSGWHNCRGSGPFIGYCC
TXAE1_ACTEQ/31-80              .PCLCVSDGPSTRGNKLSGTI..WMktggyggNGC...PKGWHFCGKSRGLLSDCC
TXH16_ANTS7/3-45               .PCLCDSDGPSVRGNTLSGTL..WL.......FGC...PSGWHNCKAHGPTIGWCC
TXH8_ANTS7/3-45                .PCLCDSDGPSVRGNTLSGTL..WL.......FGC...PSGWHNCKARGPTIGWCC
TXA12_ANTEL/3-45               .PCLCDSDGPNVRGNTLSGTY..WL.......AGC...PSGWHNCKSSGPLIGACC
TXC3_BUNCI/3-46                .ACRCDSDGPTSRGNTLTGTL..WL......tGGC...PSGWHNCRGSGPFIGYCC
TX451_NEMVE/41-83              .PCACDSDGPDIRSASLSGIV..WM.......GSC...PSGWKKCKSYYSIVADCC
TXCAN_BUNCN/3-46               .ACRCDSDGPTVRGNSLSGTL..WL......tGGC...PSGWHNCRGSGPFIGYCC
TX1_ANTXA/3-45                 .PCLCDSDGPNVRGNTLSGTY..WL.......AGC...PSGWHNCKSSGPNIGWCC
TXA1_ANTFU/3-45                .ACLCDSDGPNVRGNTLSGTI..WL.......AGC...PSGWHNCKAHGPTIGWCC
TX371_NEMVE/41-83              .PCACDSDGPDIRSASLSGIV..WM.......GSC...PSGWKKCKSYYSIVADCC
B1NWU2_ACTEQ/31-80             .PCLCVSDGPRPRGNNLSGIM..WMktggyggNGC...PKGWHFCGKSRGFFSDCC
TXA4_HETCR/2-44                .NCKCDDEGPNVRTAPLTGYV..DL.......GYC...NEGWDKCASYYSPIAECC
TX171_NEMVE/41-83              .PCACDSDGPDIRSASLSGIV..WM.......GSC...PSGWKKCKSYYSIVADCC
TX271_NEMVE/41-83              .PCACDSDGPDIRSASLSGIV..WM.......GSC...PSGWKKCKSYYSIVADCC
TXCL1_CALPA/35-76              .ECKCEGDAPDL--SHMTGTV..-Y.......FSCkggDGSWSKCNT-YTAVADCC
TXA22_ANTEL/3-45               .PCLCDSDGPNVRGNTLSGIL..WL.......AGC...PSGWHNCKAHGPTIGWCC
TXD1A_BUNCN/3-45               .PCLCDSDGPSVRGNTLSGTV..WV.......FGC...PSGWHICTSDGPTIGSCC
B1NWT7_9CNID/35-77             .PCLCDSDGPSVRGNTLSGII..WL.......AGC...PSGWHNCKKHGPTIGWCC
TXH7_ANTS7/3-45                .PCLCDSDGPSVHGNTLSGTI..WL.......AGC...PSGWHNCKAHGPTIGWCC
TXRC1_HETCR/3-45               .PCRCDSDGPSVHGNTLSGTI..WV.......GSC...ETGWHKCNTEHNLFHECC
TXA2_HETCR/2-44                t-CKCDDDGPDVRTATFTGST..EF.......ANC...NESWEKCLAVYTPVASCC
B1NWR3_9CNID/36-78             .PCLCDSDGPSVRGNTLSGII..WL.......AGC...PSGWHNCKKHGPTIGWCC
B1NWU4_ACTEQ/31-80             .PCLCVSDGPRPRGNNLSGIM..WMktggyggNGC...PKGWHFCGKSRGFFSDCC
TXCN2_BUNCN/3-46               .ACRCDSDGPTVRGDSLSGTL..WL......tGGC...PSGWHNCRGSGPFIGYCC
B1NWU6_ACTEQ/30-79             .PCLCVSDGPRPRGNNLSGTI..WMktggyggNGC...PKGWHFCGKSRGLLSDCC
DETXX_HETHE/37-79              .ACKCDDDGPDIRSATLTGTV..DL.......GSC...NEGWEKCASYYTVVADCC
TXA3_HETCR/2-44                .NCKCDDEGPYVRTAPLTGYV..DL.......GYC...NEGWEKCASYYSPIAECC
TXAC_ANTEL/3-45                .PCLCDSDGPSVRGNTLSGIL..WL.......AGC...PSGWHNCKAHGPTIGWCC
TX391_NEMVE/41-83              .PCACDSDGPDIRSASLSGIV..WM.......GSC...PSGWKKCKSYYSIVADCC
TX3_BUNGR/3-46                 .SCRCDSDGPTSRGDTLTGTL..WL......iGRC...PSGWHNCRGSGPFIGYCC
B1NWU1_ACTEQ/31-80             .PCLCVSDGPSTRGNKLSGTI..WMktggyggNGC...PKGWHFCGKSRGLLSDCC
DETX1_CRYAD/37-79              .ACKCDDDGPDVRSATFTGTV..DL.......GSC...NSGWEKCASYYTVIADCC
TXNA_CONGI/3-45                .PCRCDSDGPSVHGNTLSGTV..WV.......GSC...ASGWHKCNDEYNIAYECC
#=GR TXNA_CONGI/3-45     SS    .E---TT--TTSTT-SS-SEE..ES.......SS-...-TT-B-SSS---SSSEEE
TXD1B_BUNCN/3-45               .PCLCDSDGPSVRGDTLSGTV..WV.......FGC...PSGWHICTSDGPTIGSCC
B1NWU5_ACTEQ/31-80             .PCLCVSDGPSTRGNNLSGIM..WMktggyggNGC...PKGWHFCGKSRGFFSDCC
TXAA_ANTXA/3-47                .SCLCDSDGPSVRGNTLSGTLwlYP.......SGC...PSGWHNCKAHGPTIGWCC
#=GR TXAA_ANTXA/3-47     SS    .----TT-SSS-TT-SS-SEEE-ST.......TSS...-TT-----SS--SSSEEE
SHTX4_STIHA/37-79              .ACKCDDDGPDIRSATLTGTV..DF.......WNC...NEGWEKCTAVYTAVASCC
B1NWT5_9CNID/39-80             .SCLCASDGPTTRGNSLSGTI..WL.......FGC...PSGWGDCKG-RAIAGTCC
TX5_ANTXA/3-45                 .SCLCDSDGPSVSGNTLSGII..WL.......AGC...PSGWHNCKAHGPNIGWCC
TXA1_HETCR/2-44                .SCKCDDDGPDVRSATFTGTV..DF.......AYC...NAGWEKCLAVYTPVASCC
TXA2_RADPA/2-44                .SCKCDDDGPDVRSATFTGTV..DF.......WNC...NEGWEKCTAVYTPVASCC
B1NWT3_9CNID/37-70             .PCKCDGD------KHMSGTF..WM.......FGC...PPGWHSCVV---ANAFCC
TXA5_HETCR/2-44                .NCKCDDEGPNVRTAPLTGYV..DL.......GYC...NEGWEKCASYYSPIAECC
D0VLT9_URTCR/36-77             .PCRCDIDGPSVRG-TLSGSV..DP.......WNC...NTGWKKCTSFYTAVASCC
TXAB_ANTXA/3-47                .PCLCDSDGPRPRGNTLSGILwfYP.......SGC...PSGWHNCKAHGPNIGWCC
#=GR TXAB_ANTXA/3-47     SS    .B---SS-SS-STTTTS-SEEE--T.......TSS...-TT---S-TT--SSSEEE
DETX1_THAAS/37-79              .ACKCDDDGPDIRSATLTGTV..DL.......GSC...DEGWEKCASYYTVIADCC
TX251_NEMVE/41-83              .PCACDSDGPDIRSASLSGIV..WM.......GSC...PSGWKKCKSYYSIVADCC
TXAM3_ANTMC/29-71              .PCRCDSDGPSVHGNPLSGTI..WV.......TSC...ATGWHKCNSENELFHECC
TX7_ANTXA/3-47                 .SCLCDSDGPSVRGNTLSGTLwlYP.......SGC...PSGWHNCKAHGPTIGWCC
TXH2_ANTS7/3-45                .PCLCDSDGPSVRGNTLSGTL..WL.......AGC...PSGWHNCKAHGPTIGWCC
TX3_ANTXA/3-45                 .ACFCDSDGPSVSGNTLSGIL..WL.......AGC...PSGWHNCKAHGPNIGWCC
TXA1_STOHE/2-44                .ACKCDDEGPDIRTAPLTGTV..DL.......GSC...NAGWEKCASYYTIIADCC
#=GR TXA1_STOHE/2-44     SS    .EEE-STSSSSSSSSSEEEEE..EE.......SS-...-TTEEEEEEEEETTEEEE
GIG3_STIGI/37-79               .ACKCDDDGPDIRSATLTGTV..DL.......GSC...NEGWEKCASFYTILADCC
B1NWU3_ACTEQ/31-80             .PCLCVSDGPRPRGNNLSGIM..WMktggyggNGC...PKGWHFCGKSRGFFSDCC
TXCP1_CONPS/3-45               .PCRCDSDGPSVHGNTLSGTV..WV.......GSC...ASGWHKCNTEHNIFHECC
TXA2_ANTFU/4-46                .PCLCDSDGPSVRGNTLSGII..WL.......AGC...PSGWHNCKAHGPTIGWCC
TXA5_ANESU/3-45                .PCLCDSDGPSVRGNTLSGIL..WL.......AGC...PSGWHNCKKHKPTIGWCC
AETX1_ANEER/3-44               .PCLCANSGPNTRGNDLNGIV..WV.......FGC...PSGWHDCHG-RAMVGYCC
TX2_ANTXA/3-45                 .ACLCDADGPSVSGNTLSGIL..WL.......AGC...PSGWHNCKAHGPTIGWCC
TXCL2_CALPA/35-76              .ECKCKGDAPDL--SHMTGTV..-Y.......FSCkggDGSWSKCNT-YTAVADCC
TXA3_RADPA/2-44                .NCKCDDEGPNVRTAPLTGYV..DL.......GYC...NEGWEKCASYYSPIAECC
B1NWR0_9CNID/36-78             .PCLCDSDGPSVRGNTLSGII..WL.......AGC...PSGWHNCKKHGPTIGWCC
TXA21_ANTEL/3-45               .PCLCDSDGPSVRGNTLSGIL..WL.......AGC...PSGWHNCKAHGPTIGWCC
HAL_HALCG/2-44                 .ACRCESDGPDVRSATFTGTV..DL.......WNC...NTGWHKCIATYTAVASCC
TX4_ANTXA/3-45                 .PCLCDSDGPSVRGNSLSGII..WL.......FGC...PSGWHNCRDHGPTIGWCC
TX401_NEMVE/41-83              .PCACDSDGPDIRSASLSGIV..WM.......GSC...PSGWKKCKSYYSIVADCC
GIG2_STIGI/33-72               .PCRCDSDGPHVRGNTLTGTV..WV.......FGC...PSGWHKCQK-GS--STCC
TXA1_ANESU/3-44                .ACLCKSDGPNTRGNSMSGTI..WV.......FGC...PSGWNNCEG-RAIIGYCC
#=GR TXA1_ANESU/3-44     SS    .EEE-TTS-S--TTSSEEEEE..ES.......S--...-TT-EEE---SSSSSEEE
TXA2_ANESU/3-45                .PCLCDSDGPSVRGNTLSGII..WL.......AGC...PSGWHNCKKHGPTIGWCC
TXCN3_BUNCN/3-46               .ACRCDSDGPTVHGDSLSGTL..WL......tGGC...PSGWHNCRGSGPFIGYCC
TX6_ANTXA/3-47                 .SCLCDSDGPSVRGNTLSGILwfYP.......SGC...PSGWHNCKAHGPTIGWCC
TXA11_ANTEL/3-45               .ACLCDSDGPSVRGNTLSGTY..WL.......AGC...PSGWHNCKSSGQLIGACC
TX411_NEMVE/41-83              .PCACDSDGPDIRSASLSGIV..WM.......GSC...PSGWKKCKSYYSIVADCC
#=GC SS_cons                   .EEE-TTSSSSSTTSSSESEEE.ET.......SSS...-TTEEECCSCCCSSSEEE
#=GC seq_cons                  .sChCDSDGPslRGsoLSGhl..Wl.......uuC...PSGWHpCpuptshlu.CC
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