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Database: Pfam
Entry: Trypan_PARP
LinkDB: Trypan_PARP
Original site: Trypan_PARP 
#=GF ID   Trypan_PARP
#=GF AC   PF05887.9
#=GF DE   Procyclic acidic repetitive protein (PARP)
#=GF PI   Trypano_PARP; 
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_9554 (release 8.0)
#=GF GA   40.00 40.00;
#=GF TC   40.00 40.30;
#=GF NC   39.90 39.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   2342468
#=GF RT   Transcription of the procyclic acidic repetitive protein genes
#=GF RT   of Trypanosoma brucei. 
#=GF RA   Clayton CE, Fueri JP, Itzhaki JE, Bellofatto V, Sherman DR,
#=GF RA   Wisdom GS, Vijayasarathy S, Mowatt MR; 
#=GF RL   Mol Cell Biol 1990;10:3036-3047.
#=GF DR   INTERPRO; IPR008882;
#=GF CC   This family consists of several Trypanosoma brucei procyclic
#=GF CC   acidic repetitive protein (PARP) like sequences. The procyclic
#=GF CC   acidic repetitive protein (parp) genes of Trypanosoma brucei
#=GF CC   encode a small family of abundant surface proteins whose
#=GF CC   expression is restricted to the procyclic form of the parasite.
#=GF CC   They are found at two unlinked loci, parpA and parpB;
#=GF CC   transcription of both loci is developmentally regulated [1].  
#=GF SQ   25
#=GS D3SGT3_THISK/18-125       AC D3SGT3.1
#=GS B8GPQ1_THISH/57-202       AC B8GPQ1.1
#=GS A0A024W164_PLAFA/81-186   AC A0A024W164.1
#=GS M5A3Q6_9ACTN/14-112       AC M5A3Q6.1
#=GS Q389V1_TRYB2/1-141        AC Q389V1.1
#=GS Q581F3_TRYB2/1-127        AC Q581F3.1
#=GS A0A024WK53_PLAFA/81-183   AC A0A024WK53.1
#=GS S1NDH9_9ENTE/3654-3756    AC S1NDH9.1
#=GS A0A0G3HEB2_9CORY/476-570  AC A0A0G3HEB2.1
#=GS C7NK75_KYTSD/80-204       AC C7NK75.1
#=GS A6W0U4_MARMS/92-172       AC A6W0U4.1
#=GS Q581G0_TRYB2/1-129        AC Q581G0.1
#=GS C5YCQ9_SORBI/4-123        AC C5YCQ9.1
#=GS F9WBZ0_TRYCI/1-149        AC F9WBZ0.1
#=GS Q389V2_TRYB2/1-129        AC Q389V2.1
#=GS B0PHZ3_9FIRM/208-291      AC B0PHZ3.1
#=GS Q581F6_TRYB2/1-123        AC Q581F6.1
#=GS Q21LI5_SACD2/135-214      AC Q21LI5.1
#=GS Q21LI5_SACD2/135-214      DR PDB; 2X32 B; 1-16;
#=GS Q21LI5_SACD2/135-214      DR PDB; 2X34 B; 1-16;
#=GS Q21LI5_SACD2/135-214      DR PDB; 2X34 A; 1-16;
#=GS Q21LI5_SACD2/135-214      DR PDB; 2X32 A; 1-16;
#=GS Q581F9_TRYB2/1-114        AC Q581F9.1
#=GS A0RXY2_CENSY/77-190       AC A0RXY2.1
#=GS E1SSB7_FERBD/1549-1644    AC E1SSB7.1
#=GS F7XNB6_METZD/612-690      AC F7XNB6.1
#=GS Q8IM51_PLAF7/81-183       AC Q8IM51.1
#=GS C9P5X1_VIBME/1092-1185    AC C9P5X1.1
#=GS Q21GJ5_SACD2/1103-1197    AC Q21GJ5.1
D3SGT3_THISK/18-125                  aigaavlggltlamaptvavadegahrvvitssg----------------------------.-------------------------...DHV.G.....SV.TVPPP.EP.EPEPEPEP..EPEPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...EPEPEPEPEPEP-------------------------inagggmqv........
B8GPQ1_THISH/57-202                  .........................plavalhas--------LALLLTVTLAMPGHGQAQTAtDEQSLETSTSPGRGNGNGRVKDSDDggkTNN.GrgnnkVS.NDPEP.EP.EPEPQPEP..EPEPQPEPEPE..PQPEPEPEPQPEPEP.EPQPEP...EPEPQPEPEPEPQP-----------------------epepvvelntwyvvvq.
A0A024W164_PLAFA/81-186              ............................smkyrh----------------------------.-------ASKGSKGYSKKMTKTSSR...SRQ.C.....NDlPLEKS.EQ.ETEPELEP..EVEPEVEPEVE..PEVEPEVEPEVEPEV.EPEVEP...EVEPEVDPEVDPEND----------------------qgtgsqnnitecy....
M5A3Q6_9ACTN/14-112                  .......................agallvsacgg----------------------------.----------------------GSD...DAS.N.....DE.LAPEV.EP.APEAEPEP..VPETAAEPEPE..PE--------LEPEP.EPELEP...EPEPELEPEPEPEAAGEVIEATL--------------teweiaapteyaagtit
Q389V1_TRYB2/1-141                   ..................................MAPRSLYLLAILLFSANLFAGVGFAAAA.EGPEDKGLTKGGKGKGEKGTKVGAD...DTN.G.....TD.PDPEP.EP.EPEPEPEP..EPEPEPEPEPE..PEPEPEPEP--EPEP.EPEPEP...EPEPEPEPEPEPEPGAATLKSVALPFAVAAAALVAAF.................
Q581F3_TRYB2/1-127                   ..................................MAPRSLYLLAILLFSANLFSGVGFAAAA.EGPEDKGLTKGGKGG--KGTKVSDD...DTN.G.....TD.PDPDP.EP.EPEPEPEP..EPEPEPEP---..-----------EPEP.EPEPEP...EPEPEPEPEPEPEPGAATLKSVALPFAIAAVGLVAAF.................
A0A024WK53_PLAFA/81-183              ...........................smkyrha----------------------------.--------SKGSKGYSKKMTKTSSR...SRQ.C.....ND.LP-LE.KS.EQETEPEL..EPEVEPEVEPE..VEPEVEPEVEPEVEP.EVEPEV...EPEVDPEVDPENDQGT---------------------gsqnnitecys......
S1NDH9_9ENTE/3654-3756               ..tiagytflkvdesseakstgvvekgtheiklv----------------------------.-------------------------...---.-.....YT.KDSEP.TP.DPEPNPEP..NPEPEPEPEPT..PDPEPEPTPDPEPNP.EPNPEP...NPEPEPTPEPEP-------------------------vikngyvevv.......
A0A0G3HEB2_9CORY/476-570             .................gnssrktqllgagvana----------------------------.--------------------EAAVA...MVR.G.....VE.LAPAP.EP.EPAPEPEP..EPAPEPEPEPE..PEPEPAPEPAPAPEP.APEPAP...APEPEPAPEPKPEPE----------------------krksy............
C7NK75_KYTSD/80-204                  efapradlatkaeqiaaaqrllaiqgpgawplcs----------------------------.-------------------VKAGLT...SANgG.....AD.RNAMP.GDsAPAPKPEP..KPEPKPEPKPE..PKPEPKPEPKPEPKP.EPKPEP...KPEPAPKAEPAPEATTWT-------------------iergvnlrpaag.....
A6W0U4_MARMS/92-172                  .................saqvdglsldsegvsii----------------------------.-------------------------...---.-.....--.-----.--.----QPEP..EPEPEPEPEPE..PEPEPEPEPE--PEP.EPEPEP...EPEPEPEPEPEPEPVKK--------------------isrtdplpwatgr....
Q581G0_TRYB2/1-129                   ..................................MAPRSLYLLAVLLFSANLFAGVGFAAAA.EGPEDKGLTKGGKGKGGKGTKVSDD...DTN.G.....TD.PEPEP.EP.EPEPEPEP..EPEPEPE----..----------PEPEP.EPEPEP...EPEPEPEPEPEPEPGAATLKSVALPFAIAAVGLVAAF.................
C5YCQ9_SORBI/4-123                   ..............................hhaa---------TILLLIASLFVAVAISRAN.ARPTMRPSKMAALRHDAYGQGYVA-...--D.A.....TE.LKPEP.EP.KPTCDNCE..QPKPEPEPEPE..PEPEPEPEPEPEPKP.KPEPEP...KPEPEPEPKSE--------------------------ltcnkvhgvqt......
F9WBZ0_TRYCI/1-149                   ..................................MTPRHLCFLTVLLFGAALFSAEGSAAAA.PAPAVRRNVEVPLAKAEEPGENGTE..pGEN.G.....TE.PGENG.TE.PGENGTEPgeNGT-EPGENGTepGENGTEPGENG-TEPgENGTEPgenGTEP-GENGTEPAAGASGFMSVVMPMAFVAVGMVATF.................
Q389V2_TRYB2/1-129                   ..................................MAPRSLYLLAILLFSANLFAGVGFAAAA.EGPEDKGLTKGGKGKGEKGTKVQ--...---.-.....--.--DEV.EP.EPEPEPEP..EP----EPEPE..PEPEPEPEPEPEPEP.EPEPEP...EPEPEPEPEPEPEPGAATLKSVALPFAIAAVGLVAAF.................
B0PHZ3_9FIRM/208-291                 ........................iraaglnhld----------------------------.-------------------------...---.-.....--.----P.LP.--EPEPNP..EPEPDPEPEPD..PEPEPDPEPEPDPEP.EPDPEP...EPDPEPEPDPEPNPGGGC-------------------lifgfigmitgaart..
Q581F6_TRYB2/1-123                   ..................................MAPRSLYLLAILLFSANLFSGVGFAAAA.EGPEDKGLTKGGKGG--KGTKVSDD...DTN.G.....TD.PDPEP.EP.EPEPEPEP..EPEP-------..-----------EPEP.EPEPEP...EPEPEPEPEPEPEPGAATLKSVALPFAIAAVGLVAAF.................
Q21LI5_SACD2/135-214                 ......................lpdvylngvncs----------------------------.-------------------------...---.-.....--.--NPG.EP.EPEPEPEP..EPEPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...EPEPEPEL-----------------------------aysldatasflnfvs..
#=GR Q21LI5_SACD2/135-214      SS    ......................XXXXXXXXXXXX----------------------------.-------------------------...---.-.....--.--XXX.XX.XXXXXXXX..XXXXXXXXXXX..XXXXXXXXXXXXXXX.XXXXXX...XXXXXXXE-----------------------------EEEE-CCC-EEEEEE..
Q581F9_TRYB2/1-114                   ..................................MAPRSLYLLAILLFSANVFAGVGFAAAA.DESASNVIVKGGKGK----------...---.-.....-E.REDGP.EE.PEETGPEE..TGPEETGPEET..GPEETGPEETG---P.-EETEP...EPEP----------GAATLKSVALPIAVAAAALVAAF.................
A0RXY2_CENSY/77-190                  .......................tivgidqivpg---------------------------S.DGSYEKTLVAGGPQW-KQGGDYEIK...VQY.G.....AQ.SHVGFfEY.LGGAAAQP..EPEPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...EPEPEPEPEPEVQCGAGTI------------------lqdgs............
E1SSB7_FERBD/1549-1644               .hgetevtvtvqdkvhgsdiatttfmltvvsdgv----------------------------.-------------------------...---.-.....--.-----.--.----EPQP..EPVPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...EPEPEPEPVSSGSLGS---------------------glllmlalaml......
F7XNB6_METZD/612-690                 ...................dvrfypfvertvgep----------------------------.-------------------------...---.-.....--.-----.--.--------..-VAPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...EPEPEPEPEPEPTPGFEAIFAIAGLLAVAY-------far..............
Q8IM51_PLAF7/81-183                  ...........................smkyrha----------------------------.--------SKGSKGYSKKMTKTSSR...SRQ.C.....ND.LP-LE.KS.EQETEPEL..EPEVEPEVEPE..VEPEVEPEVEPEVEP.EVEPEV...EPEVDPEVDPENDQGT---------------------gsqnnitecys......
C9P5X1_VIBME/1092-1185               .....................qtphqvaehsdlt----------------------------.----------------------DQQ...DTA.S.....IP.AEPEP.EP.EPEPEPEP..EPEPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...EPEPEPEDKNDEPIDFATLSSKA--------------yn...............
Q21GJ5_SACD2/1103-1197               ................vfgasvnlnwlnigdals----------------------------.-------------------------...---.-.....--.PELEP.EP.EPEPEPEP..EPEPEPEPEPE..PEPEPEPEP--EPEP.EPEPEP...EPEPEPEPEPEVDPTA---------------------plactatassqegala.
#=GC SS_cons                         ......................XXXXXXXXXXXX----------------------------.-------------------------...---.-.....--.--XXX.XX.XXXXXXXX..XXXXXXXXXXX..XXXXXXXXXXXXXXX.XXXXXX...XXXXXXXE-----------------------------EEEE-CCC-EEEEEE..
#=GC seq_cons                        ...............................t.s...................................................t.........s.....sp..tsts.EP.-PEPEPEP..EPEPEPEPEPE..PEPEPEPEPcPEPEP.EPEPEP...EPEPEPEPEPEPpsss.....................h................
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