GenomeNet

Database: Pfam
Entry: Trypan_PARP
LinkDB: Trypan_PARP
Original site: Trypan_PARP 
#=GF ID   Trypan_PARP
#=GF AC   PF05887.10
#=GF DE   Procyclic acidic repetitive protein (PARP)
#=GF PI   Trypano_PARP; 
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_9554 (release 8.0)
#=GF GA   40.00 40.00;
#=GF TC   40.00 40.30;
#=GF NC   39.90 39.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   2342468
#=GF RT   Transcription of the procyclic acidic repetitive protein genes
#=GF RT   of Trypanosoma brucei. 
#=GF RA   Clayton CE, Fueri JP, Itzhaki JE, Bellofatto V, Sherman DR,
#=GF RA   Wisdom GS, Vijayasarathy S, Mowatt MR; 
#=GF RL   Mol Cell Biol 1990;10:3036-3047.
#=GF DR   INTERPRO; IPR008882;
#=GF CC   This family consists of several Trypanosoma brucei procyclic
#=GF CC   acidic repetitive protein (PARP) like sequences. The procyclic
#=GF CC   acidic repetitive protein (parp) genes of Trypanosoma brucei
#=GF CC   encode a small family of abundant surface proteins whose
#=GF CC   expression is restricted to the procyclic form of the parasite.
#=GF CC   They are found at two unlinked loci, parpA and parpB;
#=GF CC   transcription of both loci is developmentally regulated [1].  
#=GF SQ   32
#=GS Q581F3_TRYB2/1-127         AC Q581F3.1
#=GS Q389V1_TRYB2/1-141         AC Q389V1.1
#=GS W7JHD4_PLAFA/81-183        AC W7JHD4.1
#=GS S1NDH9_9ENTE/3654-3756     AC S1NDH9.1
#=GS A6W0U4_MARMS/92-172        AC A6W0U4.1
#=GS F9WBZ0_TRYCI/1-149         AC F9WBZ0.1
#=GS A0A0K1PB20_9DELT/27-115    AC A0A0K1PB20.1
#=GS A0A0J1J4W6_9FIRM/736-864   AC A0A0J1J4W6.1
#=GS Q21LI5_SACD2/135-214       AC Q21LI5.1
#=GS Q21LI5_SACD2/135-214       DR PDB; 2X32 B; 1-16;
#=GS Q21LI5_SACD2/135-214       DR PDB; 2X34 B; 1-16;
#=GS Q21LI5_SACD2/135-214       DR PDB; 2X34 A; 1-16;
#=GS Q21LI5_SACD2/135-214       DR PDB; 2X32 A; 1-16;
#=GS E1SSB7_FERBD/1549-1644     AC E1SSB7.1
#=GS F7XNB6_METZD/612-690       AC F7XNB6.1
#=GS Q8IM51_PLAF7/81-183        AC Q8IM51.1
#=GS V4T960_9RHIZ/114-235       AC V4T960.1
#=GS D3SGT3_THISK/18-125        AC D3SGT3.1
#=GS A0A166EV38_9EURY/979-1083  AC A0A166EV38.1
#=GS A0A024W164_PLAFA/81-186    AC A0A024W164.1
#=GS B8GPQ1_THISH/57-202        AC B8GPQ1.1
#=GS W7JNA2_PLAFO/81-183        AC W7JNA2.1
#=GS M5A3Q6_9ACTN/14-112        AC M5A3Q6.1
#=GS A0A024WK53_PLAFA/81-183    AC A0A024WK53.1
#=GS A0A0G3HEB2_9CORY/476-570   AC A0A0G3HEB2.1
#=GS C7NK75_KYTSD/80-204        AC C7NK75.1
#=GS A0A0C2A0Q1_9DELT/377-519   AC A0A0C2A0Q1.1
#=GS Q581G0_TRYB2/1-129         AC Q581G0.1
#=GS Q389V2_TRYB2/1-129         AC Q389V2.1
#=GS Q581F6_TRYB2/1-123         AC Q581F6.1
#=GS B0PHZ3_9FIRM/208-291       AC B0PHZ3.1
#=GS Q581F9_TRYB2/1-114         AC Q581F9.1
#=GS A0RXY2_CENSY/77-190        AC A0RXY2.1
#=GS C9P5X1_VIBME/1092-1185     AC C9P5X1.1
#=GS Q21GJ5_SACD2/1103-1197     AC Q21GJ5.1
#=GS W7QCP3_9ALTE/370-475       AC W7QCP3.1
Q581F3_TRYB2/1-127                    ...................................................MAPRSLYLLAILLFSANLFSGVGFAAAA.EGPEDKGLTK.......GGKGG--KGTKVSDD...DTN.G.....TD.PDPDP.E....P.EPEPEPEP..EPEPEPEP---..-----------EPEP.EPEPEP...E..PEPEPEPEPE....PEPGAATLKSVALPFAIAAVGLVAAF.................
Q389V1_TRYB2/1-141                    ...................................................MAPRSLYLLAILLFSANLFAGVGFAAAA.EGPEDKGLTK.......GGKGKGEKGTKVGAD...DTN.G.....TD.PDPEP.E....P.EPEPEPEP..EPEPEPEPEPE..PEPEPEPEP--EPEP.EPEPEP...E..PEPEPEPEPE....PEPGAATLKSVALPFAVAAAALVAAF.................
W7JHD4_PLAFA/81-183                   ............................................smkyrha----------------------------.--------SK.......GSKGYSKKMTKTSSR...SRQ.C.....ND.LP-LE.K....S.EQETEPEL..EPEVEPEVEPE..VEPEVEPEVEPEVEP.EVEPEV...E..PEVDPEVDPE....NDQGT---------------------gsqnnitecys......
S1NDH9_9ENTE/3654-3756                ...................tiagytflkvdesseakstgvvekgtheiklv----------------------------.----------.......---------------...---.-.....YT.KDSEP.T....P.DPEPNPEP..NPEPEPEPEPT..PDPEPEPTPDPEPNP.EPNPEP...N..PEPEPTPEPE....P-------------------------vikngyvevv.......
A6W0U4_MARMS/92-172                   ..................................saqvdglsldsegvsii----------------------------.----------.......---------------...---.-.....--.-----.-....-.----QPEP..EPEPEPEPEPE..PEPEPEPEPE--PEP.EPEPEP...E..PEPEPEPEPE....PEPVKK--------------------isrtdplpwatgr....
F9WBZ0_TRYCI/1-149                    ...................................................MTPRHLCFLTVLLFGAALFSAEGSAAAA.PAPAVRRNVE.......VPLAKAEEPGENGTE..pGEN.G.....TE.PGENG.T....E.PGENGTEPgeNGT-EPGENGTepGENGTEPGENG-TEPgENGTEPgenG..TEP-GENGTE....PAAGASGFMSVVMPMAFVAVGMVATF.................
A0A0K1PB20_9DELT/27-115               ..........................................vglgtvacg----------------------------.----------.......-------------TD...RHS.P.....KD.DWTDP.D....-.PNGPGPEP..EPEPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...E..PEPEPEPEPE....PEPVL---------------------ptvmlalrss.......
A0A0J1J4W6_9FIRM/736-864              tvavmaaadegyefrgwyedkvsdenkvsseaaynftasadrkllaefqkm----------------------------.----------.......---------------...---.-.....--.-----.-....-.--QVQPEP..DPEPKPEPKPE..PKPEPKPEPKPEPKP.EPKPEP...K..PEPAPKPEPAvakpVQLKAASIKASS--------------lkltwkkaanavs....
Q21LI5_SACD2/135-214                  .......................................lpdvylngvncs----------------------------.----------.......---------------...---.-.....--.--NPG.E....P.EPEPEPEP..EPEPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...E..PEPEPEL---....--------------------------aysldatasflnfvs..
#=GR Q21LI5_SACD2/135-214       SS    .......................................XXXXXXXXXXXX----------------------------.----------.......---------------...---.-.....--.--XXX.X....X.XXXXXXXX..XXXXXXXXXXX..XXXXXXXXXXXXXXX.XXXXXX...X..XXXXXXE---....--------------------------EEEE-CCC-EEEEEE..
E1SSB7_FERBD/1549-1644                ..................hgetevtvtvqdkvhgsdiatttfmltvvsdgv----------------------------.----------.......---------------...---.-.....--.-----.-....-.----EPQP..EPVPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...E..PEPEPEPVSS....GSLGS---------------------glllmlalaml......
F7XNB6_METZD/612-690                  ....................................dvrfypfvertvgep----------------------------.----------.......---------------...---.-.....--.-----.-....-.--------..-VAPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...E..PEPEPEPEPE....PTPGFEAIFAIAGLLAVAY-------far..............
Q8IM51_PLAF7/81-183                   ............................................smkyrha----------------------------.--------SK.......GSKGYSKKMTKTSSR...SRQ.C.....ND.LP-LE.K....S.EQETEPEL..EPEVEPEVEPE..VEPEVEPEVEPEVEP.EVEPEV...E..PEVDPEVDPE....NDQGT---------------------gsqnnitecys......
V4T960_9RHIZ/114-235                  .....tvdgnllvgggytvysdgtrdggpitnvsftnnhmgegqwgytyfy----------------------------.----------.......---------------...---.-.....-E.NRPVY.E....G.NTNDGHEL..VSTLDDQPTPR..PEPEPEPEPEPRPEP.EPEPEP...E..PRPEPEPEPE....PRDG----------------------yphagntgvpdgv....
D3SGT3_THISK/18-125                   .................aigaavlggltlamaptvavadegahrvvitssg----------------------------.----------.......---------------...DHV.G.....SV.TVPPP.E....P.EPEPEPEP..EPEPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...E..PEPEPEPEPE....P-------------------------inagggmqv........
A0A166EV38_9EURY/979-1083             .............................................ilnlak----------------------------.----------.......-----------VITD...EPN.T.....GN.DSDDA.EvtvnK.TQEPEPEE..ELEPQPKPQPI..PQPDPQPKPQPIPQP.NPQPDP...QpiPQPEPQSKPQ....PISSHASMKTTGIPIILLVITLV---lg...............
A0A024W164_PLAFA/81-186               .............................................smkyrh----------------------------.-------ASK.......GSKGYSKKMTKTSSR...SRQ.C.....NDlPLEKS.E....Q.ETEPELEP..EVEPEVEPEVE..PEVEPEVEPEVEPEV.EPEVEP...E..VEPEVDPEVD....PEND----------------------qgtgsqnnitecy....
B8GPQ1_THISH/57-202                   ..........................................plavalhas--------LALLLTVTLAMPGHGQAQTAtDEQSLETSTS.......PGRGNGNGRVKDSDDggkTNN.GrgnnkVS.NDPEP.E....P.EPEPQPEP..EPEPQPEPEPE..PQPEPEPEPQPEPEP.EPQPEP...E..PEPQPEPEPE....PQP-----------------------epepvvelntwyvvvq.
W7JNA2_PLAFO/81-183                   ............................................smkyrha----------------------------.--------SK.......GSKGYSKKMTKTSSR...SRQ.C.....ND.LP-LE.K....S.EQETEPEL..EPEVEPEVEPE..VEPEVEPEVEPEVEP.EVEPEV...E..PEVDPEVDPE....NDQGT---------------------gsqnnitecys......
M5A3Q6_9ACTN/14-112                   ........................................agallvsacgg----------------------------.----------.......------------GSD...DAS.N.....DE.LAPEV.E....P.APEAEPEP..VPETAAEPEPE..PE--------LEPEP.EPELEP...E..PEPELEPEPE....PEAAGEVIEATL--------------teweiaapteyaagtit
A0A024WK53_PLAFA/81-183               ............................................smkyrha----------------------------.--------SK.......GSKGYSKKMTKTSSR...SRQ.C.....ND.LP-LE.K....S.EQETEPEL..EPEVEPEVEPE..VEPEVEPEVEPEVEP.EVEPEV...E..PEVDPEVDPE....NDQGT---------------------gsqnnitecys......
A0A0G3HEB2_9CORY/476-570              ..................................gnssrktqllgagvana----------------------------.----------.......----------EAAVA...MVR.G.....VE.LAPAP.E....P.EPAPEPEP..EPAPEPEPEPE..PEPEPAPEPAPAPEP.APEPAP...A..PEPEPAPEPK....PEPE----------------------krksy............
C7NK75_KYTSD/80-204                   .................efapradlatkaeqiaaaqrllaiqgpgawplcs----------------------------.----------.......---------VKAGLT...SANgG.....AD.RNAMP.G....DsAPAPKPEP..KPEPKPEPKPE..PKPEPKPEPKPEPKP.EPKPEP...K..PEPAPKAEPA....PEATTWT-------------------iergvnlrpaag.....
A0A0C2A0Q1_9DELT/377-519              ........................................igglfaamllf-----------------LGAAVGVLAAS.TREGAEAIENpatvqvaGVEPR-AQAGDTGSP...ERV.V.....AT.PGAAA.A....S.EPAPTPER..AATPEPEPAPE..PDVAPEPEPEPDVAP.EPEPEP...E..PEADVEPEPK....PKPVKKQARKVAVTFVITGVA-----tatlq............
Q581G0_TRYB2/1-129                    ...................................................MAPRSLYLLAVLLFSANLFAGVGFAAAA.EGPEDKGLTK.......GGKGKGGKGTKVSDD...DTN.G.....TD.PEPEP.E....P.EPEPEPEP..EPEPEPE----..----------PEPEP.EPEPEP...E..PEPEPEPEPE....PEPGAATLKSVALPFAIAAVGLVAAF.................
Q389V2_TRYB2/1-129                    ...................................................MAPRSLYLLAILLFSANLFAGVGFAAAA.EGPEDKGLTK.......GGKGKGEKGTKVQ--...---.-.....--.--DEV.E....P.EPEPEPEP..EP----EPEPE..PEPEPEPEPEPEPEP.EPEPEP...E..PEPEPEPEPE....PEPGAATLKSVALPFAIAAVGLVAAF.................
Q581F6_TRYB2/1-123                    ...................................................MAPRSLYLLAILLFSANLFSGVGFAAAA.EGPEDKGLTK.......GGKGG--KGTKVSDD...DTN.G.....TD.PDPEP.E....P.EPEPEPEP..EPEP-------..-----------EPEP.EPEPEP...E..PEPEPEPEPE....PEPGAATLKSVALPFAIAAVGLVAAF.................
B0PHZ3_9FIRM/208-291                  .........................................iraaglnhld----------------------------.----------.......---------------...---.-.....--.----P.L....P.--EPEPNP..EPEPDPEPEPD..PEPEPDPEPEPDPEP.EPDPEP...E..PDPEPEPDPE....PNPGGGC-------------------lifgfigmitgaart..
Q581F9_TRYB2/1-114                    ...................................................MAPRSLYLLAILLFSANVFAGVGFAAAA.DESASNVIVK.......GGKGK----------...---.-.....-E.REDGP.E....E.PEETGPEE..TGPEETGPEET..GPEETGPEETG---P.-EETEP...E..PEP-------....---GAATLKSVALPIAVAAAALVAAF.................
A0RXY2_CENSY/77-190                   ........................................tivgidqivpg---------------------------S.DGSYEKTLVA.......GGPQW-KQGGDYEIK...VQY.G.....AQ.SHVGFfE....Y.LGGAAAQP..EPEPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...E..PEPEPEPEPE....VQCGAGTI------------------lqdgs............
C9P5X1_VIBME/1092-1185                ......................................qtphqvaehsdlt----------------------------.----------.......------------DQQ...DTA.S.....IP.AEPEP.E....P.EPEPEPEP..EPEPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...E..PEPEPEDKND....EPIDFATLSSKA--------------yn...............
Q21GJ5_SACD2/1103-1197                .................................vfgasvnlnwlnigdals----------------------------.----------.......---------------...---.-.....--.PELEP.E....P.EPEPEPEP..EPEPEPEPEPE..PEPEPEPEP--EPEP.EPEPEP...E..PEPEPEPEPE....VDPTA---------------------plactatassqegala.
W7QCP3_9ALTE/370-475                  ..............................tavkqssiadanvastaplad----------------------------.----------.......-----AEKKTENLAE...PQN.N.....LA.SKDEQ.A....I.IVEPEPEP..EPEPEPEPEPE..PEPEPEPEPEPEPEP.EPEPEP...E..PEPEPEPEPE....NVN-----------------------aaelateh.........
#=GC SS_cons                          .......................................XXXXXXXXXXXX----------------------------.----------.......---------------...---.-.....--.--XXX.X....X.XXXXXXXX..XXXXXXXXXXX..XXXXXXXXXXXXXXX.XXXXXX...X..XXXXXXE---....--------------------------EEEE-CCC-EEEEEE..
#=GC seq_cons                         .............................................hh..h.....................................................................s......p...s.s.c....s.psEsEPEP..EPEPEPEPEPE..PEPEPEPEPcPEPEP.EPEPEP...E..PEPEPEPEPE....Ppsst.....................h................
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