#=GF ID UPF0020
#=GF AC PF01170.13
#=GF DE Putative RNA methylase family UPF0020
#=GF AU Finn RD, Bateman A
#=GF SE Prosite
#=GF GA 21.70 21.70;
#=GF TC 21.70 21.70;
#=GF NC 21.60 21.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 11295541
#=GF RT THUMP - a predicted RNA-binding domain shared by 4-thiouridine,
#=GF RT pseudouridine synthases and RNA methylases.
#=GF RA Aravind L, Koonin EV;
#=GF RL Trends Biochem Sci 2001;26:215-217.
#=GF DR INTERPRO; IPR000241;
#=GF DR PROSITE; PDOC00969;
#=GF CC This domain is probably a methylase. It is associated with the
#=GF CC THUMP domain that also occurs with RNA modification domains [1].
#=GF SQ 3872
#=GS C9A8D5_ENTCA/167-373 AC C9A8D5.1
#=GS A9GBL8_SORC5/199-369 AC A9GBL8.1
#=GS D4QWS3_ENTFC/168-374 AC D4QWS3.1
#=GS H3X2L2_STAAU/161-368 AC H3X2L2.1
#=GS D6S8P6_PEPMA/160-366 AC D6S8P6.1
#=GS G7EM80_9GAMM/162-371 AC G7EM80.1
#=GS C8N9J1_9GAMM/163-380 AC C8N9J1.1
#=GS RLML_XANOR/161-374 AC Q5H029.1
#=GS C3WWT2_9FUSO/161-368 AC C3WWT2.1
#=GS RLML_ACIBS/175-392 AC B0VLH0.1
#=GS B3YWQ3_BACCE/155-308 AC B3YWQ3.1
#=GS B0AMC5_BACAN/163-369 AC B0AMC5.1
#=GS D4FXY3_BACNA/164-370 AC D4FXY3.1
#=GS Q8XJB3_CLOPE/162-367 AC Q8XJB3.1
#=GS F4GHH6_SPICD/164-383 AC F4GHH6.1
#=GS RLML_ACIAD/175-391 AC Q6FCR7.1
#=GS A6CGC9_9PLAN/164-369 AC A6CGC9.1
#=GS E1U9G3_LISML/163-369 AC E1U9G3.1
#=GS G9QBB1_9BACI/163-369 AC G9QBB1.1
#=GS Q2FYI6_STAA8/161-368 AC Q2FYI6.1
#=GS C7WN80_ENTFL/168-374 AC C7WN80.1
#=GS Q038W8_LACC3/162-368 AC Q038W8.1
#=GS B7K3I4_CYAP8/163-371 AC B7K3I4.1
#=GS A4VZM3_STRS2/168-306 AC A4VZM3.1
#=GS Q0K713_CUPNH/173-338 AC Q0K713.1
#=GS D4QHP8_ENTFC/168-374 AC D4QHP8.1
#=GS C3GX33_BACTU/128-280 AC C3GX33.1
#=GS D8NY72_RALSL/173-334 AC D8NY72.1
#=GS H6MAY6_ECOLX/162-376 AC H6MAY6.1
#=GS F3SL21_STRSA/167-373 AC F3SL21.1
#=GS G9W2Z8_SALET/162-376 AC G9W2Z8.1
#=GS F9L9L9_STACP/161-368 AC F9L9L9.1
#=GS D3SFH3_THISK/172-387 AC D3SFH3.1
#=GS E5Z3U4_9BACL/162-318 AC E5Z3U4.1
#=GS C2LPW8_STRSL/169-375 AC C2LPW8.1
#=GS F5NST4_SHIFL/162-376 AC F5NST4.1
#=GS E6UJ08_RUMA7/163-368 AC E6UJ08.1
#=GS C6BDQ4_RALP1/173-334 AC C6BDQ4.1
#=GS A8AVU6_STRGC/167-373 AC A8AVU6.1
#=GS H2SCK7_TAKRU/191-327 AC H2SCK7.1
#=GS A7V992_BACUN/166-371 AC A7V992.1
#=GS D5E1C2_BACMQ/164-370 AC D5E1C2.1
#=GS C0QIM2_DESAH/178-370 AC C0QIM2.1
#=GS D3A8Z8_9CLOT/151-358 AC D3A8Z8.1
#=GS H4BH49_STAAU/161-368 AC H4BH49.1
#=GS G0HK93_THES4/154-326 AC G0HK93.1
#=GS A4IN57_GEOTN/162-368 AC A4IN57.1
#=GS G8LHS8_ENTCL/162-376 AC G8LHS8.1
#=GS F0JGV9_DESDE/168-380 AC F0JGV9.1
#=GS I0QJ19_STRSL/167-373 AC I0QJ19.1
#=GS C0XLS2_LACHI/165-371 AC C0XLS2.1
#=GS E6MH42_9FIRM/171-376 AC E6MH42.1
#=GS G9ZSA5_9LACO/165-371 AC G9ZSA5.1
#=GS G0AVW1_9GAMM/162-374 AC G0AVW1.1
#=GS F2KMW0_ARCVS/145-310 AC F2KMW0.1
#=GS C7HSK3_9FIRM/161-366 AC C7HSK3.1
#=GS C7GGN2_9FIRM/320-488 AC C7GGN2.1
#=GS A3UBS0_CROAH/159-365 AC A3UBS0.1
#=GS H7C0R6_HUMAN/149-232 AC H7C0R6.1
#=GS C2HPT5_LACAI/163-368 AC C2HPT5.1
#=GS C3B1M7_BACMY/165-371 AC C3B1M7.1
#=GS C6RN97_ACIRA/175-391 AC C6RN97.1
#=GS G6BBN7_CLODI/165-371 AC G6BBN7.1
#=GS E6N7F0_9ARCH/161-369 AC E6N7F0.1
#=GS C2NUX7_BACCE/128-280 AC C2NUX7.1
#=GS Q7WD87_BORBR/280-486 AC Q7WD87.1
#=GS H5T0L4_LACLL/169-377 AC H5T0L4.1
#=GS F4V0G9_ECOLX/162-376 AC F4V0G9.1
#=GS G2JY70_LISMN/163-369 AC G2JY70.1
#=GS C5VSQ9_CLOBO/163-370 AC C5VSQ9.1
#=GS G2DXZ3_9GAMM/164-380 AC G2DXZ3.1
#=GS A9G8K1_SORC5/161-365 AC A9G8K1.1
#=GS E0PUV4_STRPY/167-373 AC E0PUV4.1
#=GS H7MGT1_STRPN/167-373 AC H7MGT1.1
#=GS B3ZUY7_BACCE/155-308 AC B3ZUY7.1
#=GS F3GCW7_PSESJ/165-382 AC F3GCW7.1
#=GS B5RVT2_RALSL/173-334 AC B5RVT2.1
#=GS B5Y3E0_PHATC/289-399 AC B5Y3E0.1
#=GS B3YRB7_BACCE/163-369 AC B3YRB7.1
#=GS C8U5B2_ECO10/162-376 AC C8U5B2.1
#=GS H5EVT3_ECOLX/162-376 AC H5EVT3.1
#=GS RLML_SODGM/162-376 AC Q2NU80.1
#=GS G3TW32_LOXAF/1-132 AC G3TW32.1
#=GS G1LSH2_AILME/189-341 AC G1LSH2.1
#=GS E0F1S1_ACTPL/165-375 AC E0F1S1.1
#=GS RLML_FRAT1/163-378 AC Q14HS5.1
#=GS Q04ZQ8_LEPBL/207-409 AC Q04ZQ8.1
#=GS C3LE23_BACAC/155-308 AC C3LE23.1
#=GS B2DRT9_STRPN/167-373 AC B2DRT9.1
#=GS A8B5G5_GIAIC/237-358 AC A8B5G5.1
#=GS H3HJL6_STRPU/189-332 AC H3HJL6.1
#=GS H3UKE8_STAEP/161-368 AC H3UKE8.1
#=GS TRM11_PONAB/188-328 AC Q5R962.1
#=GS D2G1V4_STAAU/161-368 AC D2G1V4.1
#=GS Q295G6_DROPS/160-298 AC Q295G6.2
#=GS D7AEM8_GEOSK/179-387 AC D7AEM8.1
#=GS C8WGP0_EGGLE/169-333 AC C8WGP0.1
#=GS C2S1K4_BACCE/165-371 AC C2S1K4.1
#=GS Q3DH95_STRAG/167-373 AC Q3DH95.1
#=GS F4SX27_ECOLX/162-376 AC F4SX27.1
#=GS F9JBV0_ACIBA/175-392 AC F9JBV0.1
#=GS B1HAP3_BURPE/174-332 AC B1HAP3.1
#=GS E8SH51_STAPH/161-368 AC E8SH51.1
#=GS D5T5P4_LEGP2/163-374 AC D5T5P4.1
#=GS RLML_SALA4/162-376 AC B5F1U5.1
#=GS Q6MPB2_BDEBA/162-370 AC Q6MPB2.1
#=GS D2VYC5_NAEGR/279-431 AC D2VYC5.1
#=GS E5T0V6_TRISP/203-348 AC E5T0V6.1
#=GS F0CS11_SALMO/162-376 AC F0CS11.1
#=GS E4VWU0_BACFG/165-370 AC E4VWU0.1
#=GS H1HPX7_9BACT/165-370 AC H1HPX7.1
#=GS D1D9N9_NEIGO/165-371 AC D1D9N9.1
#=GS RLML_PHOPR/162-375 AC Q6LRA0.1
#=GS H4PX32_ECOLX/162-376 AC H4PX32.1
#=GS E5CMK7_STAHO/161-368 AC E5CMK7.1
#=GS H0DBW6_STAAU/161-368 AC H0DBW6.1
#=GS D3HNB0_LEGLN/163-374 AC D3HNB0.1
#=GS A4C1H3_9FLAO/166-372 AC A4C1H3.1
#=GS H7PQ64_STRPN/167-373 AC H7PQ64.1
#=GS A3YVV1_9SYNE/187-401 AC A3YVV1.1
#=GS B3I7T8_ECOLX/162-376 AC B3I7T8.1
#=GS B3ZTU5_BACCE/163-369 AC B3ZTU5.1
#=GS B5IEP2_ACIB4/143-305 AC B5IEP2.1
#=GS D4YGX6_9LACT/163-369 AC D4YGX6.1
#=GS Q17E68_AEDAE/190-325 AC Q17E68.1
#=GS H1SUS2_STAAU/161-368 AC H1SUS2.1
#=GS F0AFF9_NEIME/165-371 AC F0AFF9.1
#=GS B5E7B4_STRP4/167-373 AC B5E7B4.1
#=GS F5HK68_ANOGA/191-328 AC F5HK68.1
#=GS H3ZR77_THELI/191-360 AC H3ZR77.1
#=GS C7VBR9_ENTFL/168-374 AC C7VBR9.1
#=GS E7J395_ECOLX/162-376 AC E7J395.1
#=GS G6PQK8_STRPN/167-373 AC G6PQK8.1
#=GS A2SC20_METPP/188-349 AC A2SC20.1
#=GS D8IL20_LACSC/162-368 AC D8IL20.1
#=GS E4T8Z8_RIEAD/166-371 AC E4T8Z8.1
#=GS C7HJ79_CLOTM/163-369 AC C7HJ79.1
#=GS B5URQ9_BACCE/163-369 AC B5URQ9.1
#=GS D3QCU8_STALH/161-368 AC D3QCU8.1
#=GS D4JW04_9FIRM/162-368 AC D4JW04.1
#=GS F2LZW2_LACAL/163-368 AC F2LZW2.1
#=GS D1VVQ9_9FIRM/163-368 AC D1VVQ9.1
#=GS E9W5U4_ECOLX/162-376 AC E9W5U4.1
#=GS C8ABW8_STAAU/161-368 AC C8ABW8.1
#=GS G7S3L4_STRSU/167-373 AC G7S3L4.1
#=GS F5Y4N1_RAMTT/167-333 AC F5Y4N1.1
#=GS C0Z0B7_LACRE/163-370 AC C0Z0B7.1
#=GS D1VWQ2_9BACT/163-368 AC D1VWQ2.1
#=GS E6RDV4_CRYGW/186-315 AC E6RDV4.1
#=GS G5YEH9_ECOLX/162-376 AC G5YEH9.1
#=GS H7DX36_9FIRM/163-369 AC H7DX36.1
#=GS E2KEZ2_ECO57/162-376 AC E2KEZ2.1
#=GS G6AXS3_9BACT/164-369 AC G6AXS3.1
#=GS H1SJP1_STAAU/161-368 AC H1SJP1.1
#=GS H1H545_9FLAO/159-365 AC H1H545.1
#=GS Q74JB6_LACJO/163-368 AC Q74JB6.1
#=GS H3S753_STAAU/161-368 AC H3S753.1
#=GS F3GYA0_PSESX/6-194 AC F3GYA0.1
#=GS G5HZJ3_9CLOT/164-371 AC G5HZJ3.1
#=GS C8PVI9_9GAMM/176-403 AC C8PVI9.1
#=GS B0NZ33_9CLOT/164-370 AC B0NZ33.1
#=GS D7JEU3_9BACT/161-366 AC D7JEU3.1
#=GS A6DTJ8_9BACT/170-377 AC A6DTJ8.1
#=GS F3XSL4_9FLAO/165-372 AC F3XSL4.1
#=GS F3W7Z9_STRPN/167-373 AC F3W7Z9.1
#=GS A4BHH9_9GAMM/167-385 AC A4BHH9.1
#=GS D4LUQ6_9FIRM/164-371 AC D4LUQ6.1
#=GS C2MGV2_BACCE/101-256 AC C2MGV2.1
#=GS E0GUM9_ENTFL/168-374 AC E0GUM9.1
#=GS G6L7T6_STRPN/167-373 AC G6L7T6.1
#=GS C9ZND4_TRYB9/355-605 AC C9ZND4.1
#=GS C0N217_9GAMM/166-383 AC C0N217.1
#=GS F5S6U8_9NEIS/164-371 AC F5S6U8.1
#=GS RLML_YERP3/162-376 AC A7FJT9.1
#=GS G2KTN1_LACSM/163-370 AC G2KTN1.1
#=GS C5EKX7_9FIRM/164-371 AC C5EKX7.1
#=GS C2ZXU2_BACCE/128-280 AC C2ZXU2.1
#=GS C1GW91_PARBA/182-309 AC C1GW91.1
#=GS H3DP43_TETNG/191-325 AC H3DP43.1
#=GS E7RER1_9BACL/155-296 AC E7RER1.1
#=GS A3XN27_LEEBM/165-371 AC A3XN27.1
#=GS G4D156_9FIRM/162-365 AC G4D156.1
#=GS H5GPE6_ECOLX/162-376 AC H5GPE6.1
#=GS RLML_SHELP/162-373 AC A3QDY0.1
#=GS G2HHQ5_PANTR/292-478 AC G2HHQ5.1
#=GS I0SRL4_STROR/167-373 AC I0SRL4.1
#=GS Q73CS9_BACC1/122-276 AC Q73CS9.1
#=GS RLML_PSEP1/165-382 AC A5W6K7.2
#=GS D7WFW0_BACCE/163-369 AC D7WFW0.1
#=GS F8FNL9_PAEMK/165-371 AC F8FNL9.1
#=GS G6K9I1_STRPN/167-373 AC G6K9I1.1
#=GS Q31DD0_PROM9/162-370 AC Q31DD0.1
#=GS F7EY33_MONDO/267-393 AC F7EY33.1
#=GS Q7V5I2_PROMM/162-370 AC Q7V5I2.1
#=GS C2NDE7_BACCE/155-309 AC C2NDE7.1
#=GS A0YNQ6_LYNSP/162-370 AC A0YNQ6.1
#=GS A5MNS6_STRPN/167-373 AC A5MNS6.1
#=GS F6R2E5_XENTR/255-424 AC F6R2E5.1
#=GS TRM11_CHICK/190-344 AC Q6YJI5.1
#=GS F3TAW5_STAAU/161-368 AC F3TAW5.1
#=GS F3Z379_DESAF/168-376 AC F3Z379.1
#=GS A9B9F3_PROM4/162-370 AC A9B9F3.1
#=GS F3TJG7_STAAU/161-368 AC F3TJG7.1
#=GS E3QYW3_COLGM/181-300 AC E3QYW3.1
#=GS E7P474_PSESG/165-382 AC E7P474.1
#=GS H0NTR5_BACCE/163-369 AC H0NTR5.1
#=GS D1QQ06_9BACT/165-370 AC D1QQ06.1
#=GS H0UAH1_BRELA/158-364 AC H0UAH1.1
#=GS I0MNQ4_SALET/162-376 AC I0MNQ4.1
#=GS G6Z6H6_VIBCL/162-375 AC G6Z6H6.1
#=GS F6T7Z0_HORSE/225-411 AC F6T7Z0.1
#=GS D0WBL3_NEILA/165-371 AC D0WBL3.1
#=GS B6BTD9_9PROT/166-372 AC B6BTD9.1
#=GS G9KTA9_MUSPF/203-354 AC G9KTA9.1
#=GS H4T5V2_ECOLX/162-376 AC H4T5V2.1
#=GS H4M5E2_ECOLX/162-376 AC H4M5E2.1
#=GS C0S5C1_PARBP/182-308 AC C0S5C1.1
#=GS Q5JID5_PYRKO/154-326 AC Q5JID5.1
#=GS H4VDW1_ECOLX/162-376 AC H4VDW1.1
#=GS E8HDA6_ECO57/162-376 AC E8HDA6.1
#=GS D4T4E6_9XANT/161-374 AC D4T4E6.1
#=GS E0FK25_ACTPL/165-375 AC E0FK25.1
#=GS E8IXN7_ECOLX/162-376 AC E8IXN7.1
#=GS H7MLS9_STRPN/167-373 AC H7MLS9.1
#=GS H5HMF3_ECOLX/162-376 AC H5HMF3.1
#=GS B9M158_GEOSF/163-371 AC B9M158.1
#=GS E1G405_LOALO/177-280 AC E1G405.1
#=GS A9IIR0_BORPD/260-465 AC A9IIR0.1
#=GS Q1JY11_DESAC/162-342 AC Q1JY11.1
#=GS C1CBF3_STRP7/167-373 AC C1CBF3.1
#=GS F3RL10_LISMN/163-369 AC F3RL10.1
#=GS F0HM09_9ACTN/169-333 AC F0HM09.1
#=GS G4NST3_BACPN/164-370 AC G4NST3.1
#=GS E1ICV2_9CHLR/182-347 AC E1ICV2.1
#=GS B1JVX3_BURCC/175-335 AC B1JVX3.1
#=GS H0L5K9_SALMO/162-376 AC H0L5K9.1
#=GS B0WF94_CULQU/190-322 AC B0WF94.1
#=GS RLML_ECOSM/162-376 AC B1LJR4.1
#=GS Q5N5E0_SYNP6/78-286 AC Q5N5E0.1
#=GS E3DV11_BACA1/164-370 AC E3DV11.1
#=GS C6L9W3_9FIRM/318-476 AC C6L9W3.1
#=GS G5KZW9_STRSU/167-373 AC G5KZW9.1
#=GS E0TID5_PARBH/214-410 AC E0TID5.1
#=GS F9CUJ1_9ARCH/151-310 AC F9CUJ1.1
#=GS B1UMS3_BACAN/163-369 AC B1UMS3.1
#=GS C3IHB7_BACTU/165-371 AC C3IHB7.1
#=GS H7FY42_9LACO/162-368 AC H7FY42.1
#=GS A9WJP8_CHLAA/183-353 AC A9WJP8.1
#=GS F8NTG9_SERL9/31-95 AC F8NTG9.1
#=GS C8PM90_9SPIO/167-393 AC C8PM90.1
#=GS G2S5Z2_ENTAL/168-382 AC G2S5Z2.1
#=GS G0VVQ9_PAEPO/157-322 AC G0VVQ9.1
#=GS D4LJZ1_9FIRM/164-371 AC D4LJZ1.1
#=GS C4RP83_9ACTO/177-342 AC C4RP83.1
#=GS F8AK05_METOI/221-389 AC F8AK05.1
#=GS A5TTH4_FUSNP/161-368 AC A5TTH4.1
#=GS E1LJG1_STRMT/167-373 AC E1LJG1.1
#=GS C2VPP6_BACCE/155-230 AC C2VPP6.1
#=GS I0NZ89_STRPN/167-373 AC I0NZ89.1
#=GS RLML_SHEPA/162-373 AC A8H3Y1.1
#=GS C2SWY6_BACCE/128-280 AC C2SWY6.1
#=GS F9BLV6_VIBCL/162-375 AC F9BLV6.1
#=GS Q9N4H1_CAEEL/180-331 AC Q9N4H1.2
#=GS D1PCU1_9BACT/165-370 AC D1PCU1.1
#=GS E3CSI8_STRVE/167-373 AC E3CSI8.1
#=GS C8KSD3_STAAU/161-368 AC C8KSD3.1
#=GS D7ZT71_ECOLX/162-376 AC D7ZT71.1
#=GS F4MNE0_9FLAO/165-371 AC F4MNE0.1
#=GS C6GR46_STRSX/167-373 AC C6GR46.1
#=GS C9ANM9_ENTFC/168-374 AC C9ANM9.1
#=GS B5IZ78_9RHOB/154-342 AC B5IZ78.1
#=GS RLML_SHEB5/162-374 AC A3D5Q0.1
#=GS D9RVR8_PREMB/164-369 AC D9RVR8.1
#=GS Q9SVV0_ARATH/6-133 AC Q9SVV0.1
#=GS G0VD87_NAUCC/190-309 AC G0VD87.1
#=GS Q4UHG6_THEAN/223-392 AC Q4UHG6.1
#=GS C2JIZ2_ENTFL/168-374 AC C2JIZ2.1
#=GS G5LM01_SALET/70-284 AC G5LM01.1
#=GS A6KZC0_BACV8/165-370 AC A6KZC0.1
#=GS D5HD52_SALRM/186-361 AC D5HD52.1
#=GS E1ZLU0_CHLVA/308-446 AC E1ZLU0.1
#=GS RLML_SALPK/162-376 AC B5BBL9.1
#=GS C3Q9L0_9BACE/165-370 AC C3Q9L0.1
#=GS F3ME26_9BACL/163-369 AC F3ME26.1
#=GS D3A4G4_NEISU/164-370 AC D3A4G4.1
#=GS C3LMH1_VIBCM/162-375 AC C3LMH1.1
#=GS A8SNY0_9FIRM/164-371 AC A8SNY0.1
#=GS F7JPB6_9FIRM/164-371 AC F7JPB6.1
#=GS F9FDA0_FUSOF/221-341 AC F9FDA0.1
#=GS D8H7R9_BACAI/163-369 AC D8H7R9.1
#=GS F6ZL88_MACMU/188-254 AC F6ZL88.1
#=GS G9SHM1_CITFR/162-376 AC G9SHM1.1
#=GS D5VYW0_CLOB2/162-367 AC D5VYW0.1
#=GS E5CRG0_9STAP/161-368 AC E5CRG0.1
#=GS Q5FVM9_RAT/212-325 AC Q5FVM9.1
#=GS C6YWB4_9GAMM/163-378 AC C6YWB4.1
#=GS E5S6T3_TRISP/148-292 AC E5S6T3.1
#=GS D4FIP4_STAEP/161-368 AC D4FIP4.1
#=GS H7QF35_STRPN/157-363 AC H7QF35.1
#=GS E6KKU0_STRSA/167-373 AC E6KKU0.1
#=GS A5TDR1_BURML/174-332 AC A5TDR1.1
#=GS Q2FQP4_METHJ/149-313 AC Q2FQP4.1
#=GS E6HHW7_ENTFL/168-374 AC E6HHW7.1
#=GS H9ZC16_MACMU/188-328 AC H9ZC16.1
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#=GS B0S9B9_LEPBA/146-349 AC B0S9B9.1
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