GenomeNet

Database: Pfam
Entry: XhoI
LinkDB: XhoI
Original site: XhoI 
#=GF ID   XhoI
#=GF AC   PF04555.8
#=GF DE   Restriction endonuclease XhoI
#=GF AU   Kerrison ND
#=GF SE   DOMO:DM04409;
#=GF GA   25.00 25.00;
#=GF TC   71.30 35.80;
#=GF NC   20.00 19.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   3001639
#=GF RT   Nucleotide sequence of the PaeR7 restriction/modification system
#=GF RT   and partial characterization of its protein products. 
#=GF RA   Theriault G, Roy PH, Howard KA, Benner JS, Brooks JE, Waters AF,
#=GF RA   Gingeras TR; 
#=GF RL   Nucleic Acids Res 1985;13:8441-8461.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR007636;
#=GF CC   This family consists of type II restriction enzymes
#=GF CC   (EC:3.1.21.4) that recognise the double-stranded sequence CTCGAG
#=GF CC   and cleave after C-1.
#=GF SQ   48
#=GS C6E3B4_GEOSM/21-168   AC C6E3B4.1
#=GS G4FXS3_9GAMM/1-57     AC G4FXS3.1
#=GS E8WPJ2_GEOS8/28-223   AC E8WPJ2.1
#=GS T2X1_XANVA/27-206     AC Q9KVZ7.1
#=GS E8JLP0_9ACTO/27-223   AC E8JLP0.1
#=GS E6KUT0_9ACTO/26-218   AC E6KUT0.1
#=GS B3EK31_CHLPB/23-217   AC B3EK31.1
#=GS C7M1D1_ACIFD/7-198    AC C7M1D1.1
#=GS H2CG34_9LEPT/26-220   AC H2CG34.1
#=GS C4XNH9_DESMR/28-223   AC C4XNH9.1
#=GS E6Q237_9ZZZZ/25-235   AC E6Q237.1
#=GS E0QQ27_9ACTO/22-207   AC E0QQ27.1
#=GS A4ALN4_9ACTN/1-71     AC A4ALN4.1
#=GS A1BHP7_CHLPD/28-222   AC A1BHP7.1
#=GS Q7N3K6_PHOLL/28-223   AC Q7N3K6.1
#=GS A4ALN1_9ACTN/23-213   AC A4ALN1.1
#=GS E5XZ97_9BIFI/21-212   AC E5XZ97.1
#=GS A1Y2X2_9BACT/28-223   AC A1Y2X2.1
#=GS B6AP66_9BACT/23-219   AC B6AP66.1
#=GS G2MQR7_9ARCH/24-217   AC G2MQR7.1
#=GS E3EPZ4_BIFBS/21-211   AC E3EPZ4.1
#=GS A1WFA1_VEREI/28-125   AC A1WFA1.1
#=GS A7B9F9_9ACTO/3-170    AC A7B9F9.1
#=GS G6IC59_9DELT/29-223   AC G6IC59.1
#=GS D9UI71_9ACTO/22-214   AC D9UI71.1
#=GS F8CQZ2_MYXFH/1-172    AC F8CQZ2.1
#=GS D5MMJ7_9BACT/30-224   AC D5MMJ7.1
#=GS T2A1_AZOBR/28-181     AC P26919.1
#=GS F4KTK4_HALH1/26-217   AC F4KTK4.1
#=GS E3IT40_DESVR/28-223   AC E3IT40.1
#=GS D4CRF2_9FIRM/27-216   AC D4CRF2.1
#=GS Q72WR9_DESVH/28-223   AC Q72WR9.1
#=GS A3EW32_9BACT/28-223   AC A3EW32.1
#=GS B7DVE2_9BACL/31-229   AC B7DVE2.1
#=GS Q8VT53_XANVA/27-222   AC Q8VT53.1
#=GS D8P7K3_9BACT/180-230  AC D8P7K3.1
#=GS G7GAB8_9GAMM/28-223   AC G7GAB8.1
#=GS E6QII0_9ZZZZ/28-221   AC E6QII0.1
#=GS C2KN83_9ACTO/22-207   AC C2KN83.1
#=GS A7IAU1_METB6/21-211   AC A7IAU1.1
#=GS G7WKS3_METH6/13-206   AC G7WKS3.1
#=GS E8MU51_BIFL1/1-145    AC E8MU51.1
#=GS D8P7K3_9BACT/23-186   AC D8P7K3.1
#=GS C6E3B4_GEOSM/176-228  AC C6E3B4.1
#=GS G4FXS3_9GAMM/60-152   AC G4FXS3.1
#=GS T2V1_GEOSE/1-199      AC P43421.1
#=GS H6SPY2_RHOPH/36-228   AC H6SPY2.1
#=GS T2P7_PSEAI/28-223     AC P05104.3
C6E3B4_GEOSM/21-168              ...............avragg--------------NGVLGGKTLDAFAEIIKDVVK-GSLENAMMC.GRGCVAEIPGFYRPHKSWDLIVID.....EGKLVAAIEFKSQIGP-IGNNFNNRTEEVLGSSLDLQTAIEENAFGLEA.NVFSGYIIVVEDSPKSRANPK..I.K.M.KY.FPVMEGF................---------------------------------------------laneder.......
G4FXS3_9GAMM/1-57                .....................---------------------------------------------.-------------------MLVVH.....EKRLLGVFEFKSQVG-SFGNNFNNRSEEVIGSAADLWVAHHHGAYGGL-.---------------------..-.-.-.--.-------................---------------------------------------------prsrs.........
E8WPJ2_GEOS8/28-223              .....................KKQIEAGKADQGERAGVTSGKNMDGFIALIIDLIRANGLDHAEIH.QKRAVLTLPGYFRPTKLWDLLVIH.....KGELIAAVELKSQVGPSFGNNFNNRTEEAIGTAHDLWTAYREEAFGKQP.RPFVGWLMMVEDAPESRAAVR..D.A.S.PH.FPVFDEF................KGASYIKRYDLLCQRLVKEQLYTTAALITSERNAVSTGAFSEIS-a.............
T2X1_XANVA/27-206                ...................le---NDEERSQGGERSGVLGGRNMDGFLAMIEGIVRKNGLPDAEVCiKGRPNLTLPGYYRPTKLWDVLVFD.....GKKLVAAVELKSHVGPSFGNNFNNRAEEAIGTAHDLATAIREGILGDQL.PPFTGWLILVEDCEKSKRAVR..D.S.S.PH.FPVFPDF................KGASYLTRYEVLCRKLILK--------------------------gftprpqsll....
E8JLP0_9ACTO/27-223              ...................ar--QALRGDADRGGRGQVTAGKNMDGFVHLIHDVADRAGLPKDSVL.VERRAVTLPGFFRPSKSWDVTVVH.....RGALLAVIEFKSQAGTSMGNNFNNRSEEAVGSAYDLRCAYDEGLLGQID.PPFIGWFMFVEENSASTRPHR..D.G.T.QYlFEIDHVM................RRGSYIDRYVELCQRLTATGLYTSCALVSAPASSITSGDFT----vhsd..........
E6KUT0_9ACTO/26-218              ...............enqggl-----SGIKDTGNRAAVTGGKQMDLMQAVVADLWMSDPEIHLEVR.-TTGHNDLPTYFRPSKNWDLVVLY.....RGALIAAMEFKSQRGPSFGNNFNNRTEEALGLAADSQMAVERGLFGI-L.KPWFGFIMLVERAVGSTRPVR..V.PpN.MP.FPADPIF................HGKSYIGRYRIFFERMIAEGNYDAVALLTA---EANSGEYQEPS-p.............
B3EK31_CHLPB/23-217              .................kkqg---SSTGKKDAGNRSAVTGGKHLDGFIKLLTELLAEAGLPDSAIH.--VKSTTLPGYFRPTKNWDLLVVV.....DRILLASIELKAHIGPSFGNNFNNRVEEALGNSTDLLTAYREGKFKPSQ.KPWLGWLMLLEDAPKSTTPVR..V.D.E.PH.FEVFPEF................KEASYAKRYGLFCERLMRERLYDGACLIMSDKAGGLKGKFTEP--ns............
C7M1D1_ACIFD/7-198               .............qtvkqmgg---------SAGTRGAVTGGAQMGALEVLLTDVLVDAGLEPDHVR.-VRTALELPGYYRPERKWDLLVVV.....DGQLLVAVEFKSQVGPSFGNNFNNRTEEAIGNAEDIWTAYREGRFGKHP.APFLGYFFLLEDCAKVHAPVR..N.V.E.PY.FPVDPIF................AGASYAKRYEVLCDRLVLERKYSAGCLTLATNSKP----------tkvtfpse......
H2CG34_9LEPT/26-220              .................ekqg---EASGTKDAGNRSSVTGGAQLDGFIELFAKIARDSGLTDSEIH.--MKETTLPGYYRPTKEWDLVLYA.....DGDLIASVEFKSHIGPSFGNNFNNRVEEALGSATDLRTAYREGAMKQSI.KPWMGYFMLLEDHPKSATPVK..V.R.E.PY.FPVLPDF................KEASYQRRYVEFCRRLVLEGLYDSACLLFSAESTGRSGDFTEPS-t.............
C4XNH9_DESMR/28-223              .....................QKQIESGKADQGERAGVTGGKNMDGFIALVLDIVRANGLAHAEIH.QSRAVLTLPGYFRPTKLWDLLVIF.....KGELIAAIELKSHVGPSFGNNFNNRTEEAIGTAHDLWTAYREEAFGKQP.RPFVGWLMLVEDAPESRSPVR..D.S.S.PH.FPVFPEF................KGASYLKRYDILCQRLVQEQLYTTAAVLTSPRSAAETGEVSDMS-s.............
E6Q237_9ZZZZ/25-235              .....................EKQKSSGHVDAGSRGSVTGGGHIAPLEDLVKEVLVSCGVPGNAIF.-QNQGLELPGYYRAEKCWDLLVVA.....NEKLHVAIEFKSQVGPSFGNNFNNRTEEAVGNAVDLQRALQERTLGNTVaPPFLGYVFLLEDCGAVHKRVR..L.S.E.PH.FCVDHAFlapppsvhdrverknrSGVGYAKRYERLLERLLLERKYDAACLTLTTRGDPTT--------vtfpnea.......
E0QQ27_9ACTO/22-207              .............eqqqlsal-----GGRAQGGTRASVTGGKHLAGVNQLILEELERLGITGLKHY.-TNRQATVPGYYRASKSWDLLVLR.....DDEPALALEYKSMTG-SEGKNLNNRIDEVIGAAQDLHRAQQTGLLPKEL.K--RGYIFLMEVTPAVLNPVG..T.S.T.KV.GTLDPIF................ESTCYLERMAIMCERLRNDGLYGMAWA------------------lgvvrnpig.....
A4ALN4_9ACTN/1-71                .....................----------------------MDGFDTVIAGLVESNARDGAELS.KTRRLNTVPGYFRVMKDRDLLVVR.....KGALVAAIELESQVGPGFGMNFPN-------------------------.---------------------..-.-.-.--.-------................---------------------------------------------..............
A1BHP7_CHLPD/28-222              .....................QKQLLTGKADHGERAGVTAGKNMDGFLALVLDIIQANGLAHAEIH.QNRSMLTLPGYFRPTKLWDLLVIY.....KGELIAAIELKSQVG-SFGNNFNNRTEEAIGTAYDLWTAYREEAFGKQP.RPFVGWLMMVEDAPKSRCAVR..D.A.S.PH.FPVFGEF................EGASYLMRYDLLCQKLVKEQLYTTAALITSTRCAAETGEFSEMS-s.............
Q7N3K6_PHOLL/28-223              .....................QKQIESGKADQGERAGVTAGKNMDGFLALVLDIIKANGLAHAEIH.QNRAMLTLPGYFRPTKLWDLLVLY.....KGQLIAAIELKSQVGPSFGNNFNNRTEEAIGTAHDLWTAFREEAFGKQP.RPFVGWMMMVEDASESRKSVR..D.S.S.PH.FPVFEEF................KGASYLKRYDLLCQRLVQEQLYTTAAVIAAERSAVNTGDFAELS-s.............
A4ALN1_9ACTN/23-213              ....................r-RQKEEGKKDAGAQA--RNARHMKKLGTFVRQMFVNAGLSEADVM.---VNGVIPGYFRRSKNWDVVATY.....KGQLVALVELKSQVG-SNDSNGNNRIEEALGNPKDAATAQELNQVFGKL.PIWTAFGVVFGSSPENAKAVG.lP.S.N.PL.FPLDPVF................NGMTYGRQWEIAIERFIQTGSYSAGWMVTSWVSAEGQVKYV----epva..........
E5XZ97_9BIFI/21-212              ...................ea--QAAAGHSDQGARQGITSGKHLDPIAAIIRDDLINAGFHPDEVY.DQGRMCTLPGWFRPTKNWDLLALD.....NGELVSAIELKS-INSSFGNNANNRAEESIGSAFDAHTAFDEHLLGSSSiPPVMGYVMIVHDCPDSRIVGR.gV.R.S.AH.FPIDPDF................EGASYLDRFLLLCDRLRRKSLYQAVWLVFA---------------npedgvayep....
A1Y2X2_9BACT/28-223              .....................QKQIESGKADQGERAGVTGGKNMDGFLALVLDVIKANGLAHAEIH.QNRAMLTLPGYFRPTKLWDLLVIY.....KGELIAAIELKSHVGPSFSNNFNNRTEEAIGTAHDLWTAYREEAFGKQP.RPFVGWLMMVEDAPESRRPVR..D.S.S.PH.FPVFEEF................KGASYLTRYDLLCQRLVQEQLYTTAAVIAAERSAVDTGNFTELS-s.............
B6AP66_9BACT/23-219              ................qeqqg---SKTGIKDAGNRSAVTGGKHADGFVKLLGKIVQEAGIPQAQIY.-IDNKRSLPSYYRPSKEWDIIVKV.....ENDLIAVIEVKSHVG-SFGNNFNNRVEEALGSATDFWAAYREATFSPSA.RPWLGYLIMLEDHPNSTRPCK..T.K.KlPH.YPMREEF................QGVSYARRYEIFCERLVRERLYDAACFLMSSAIGGLEGKYSEP--ni............
G2MQR7_9ARCH/24-217              ....................a-EQQESEDAARGRRAEVLGGRQLDGFATVCEEILMEAGVPEKSIY.-FDHEATLPGFFRATKRWDLAVIH.....EGELLAAIEFKSIT-SSFGNNLNNRTEEALGSPTDLYTAYEEGAYDPSP.RPWLGYLMLMSENGNSTGSVR..V.S.E.PH.FDVLEEF................DGASYVDRGEQLCLRLLRQRLYDGCVFLLSDAEGGLDGEFWEP--qe............
E3EPZ4_BIFBS/21-211              ...................aa--QAANGRADQGRRSAVTSGKHLDPVAGIIRNDLIDLGFHEDEVF.HTGRACTLPGWFRPTKDWDLLALD.....DGELVSAIELKS-ISSSFGNNANNRAEESIGSVVDAIEAYNERLYGNCSiPPVMGYAMIVCDCDESRSTSArpA.H.S.PH.FDIDEAF................KGVSYLDRFHILCDRLRRKSLYNAVWLVFA---------------rpdegiay......
A1WFA1_VEREI/28-125              ....................s-KQKESGKADQGERAAVTGGKNMHGVSRLVVDLVKANGLPNAQVH.QQRAVLTLPGYFRPTKLWDLLVID.....NGRLIAAVEFKSHVGPSFGNDFNNRT-----------------------.---------------------..-.-.-.--.-------................---------------------------------------------gsp...........
A7B9F9_9ACTO/3-170               alqsavselwqsdpslsveir---------------------------------------------.-YDTSADLPAYFRPAKNWDLIVLY.....RGALIAAMEFKSQRGPSFGNNFNNRTEEALGLAADSQMAAQRGLFGT-L.KPWFGFLMLVEDTDKSTNPVR..LpK.N.MP.FPPDPIF................EGESYIGRYRIFFERMVSEGYYDAAALVTAKE---GSGDFDE---psp...........
G6IC59_9DELT/29-223              .....................EKQKKSGKVDYGLRGAVTGGAQMDGFIELFARLIISTGLDAHFIQ.-RKGALDLPGYFRPTKEWDLLVVK.....DGKLIAAIEAKSQVGPSFGNNFNNRTEEAMGSALDLWTAYREGAFHTSP.QPFLGYFFMLEDCQASTRPVR..V.R.E.PH.FHVFPEF................KGASYMKRYEIFCRKLVLERHYTASAFITSNRTDGPEGIFSTPS-e.............
D9UI71_9ACTO/22-214              ..........qreqsaikaav---------GAGTAGSVRGGKHFDAIAILLSKFFLEAGYPPESIRvAKKQGLELPGYYRPQKQWDLVVVH.....EGVLVAAFELKALGGPSFGNNYNNRVEEALGSAVDLRRAALAELYP-KE.KPWLGYFFIMEDGSGSRRPVS..I.A.K.GA.LPADSIW................HGTSYQDRFGIFCERLVAEQLYDAACYVTSSA-------------edpkpvel......
F8CQZ2_MYXFH/1-172               .....................----------------------MNGFCHLITELLQQNGLEKEHIH.-IEKKLELPGYFRPTKKWDMVVLF.....EERLVAALEFKSMAG-SFGNNFNNRAEEALGAGIDVKMAASKGAFGRDS.RPWLGWLMLLEDSRKSTTPVS..V.K.E.PH.FKVLPEF................QGKSIAGRFELLLRKLVNEELFSAAALLMSSREAGQTGQYTEP--vk............
D5MMJ7_9BACT/30-224              ....................d-RQKQTGKADQGLRSAVTGGAQMDGFIDLFTELITAAGIPARYIF.-RSKDVELPGFFRPTKEWDLLVIR.....EKTLLIAIEAKSQVGPSFGNNFNNRTEEAMGSALDLWTAYREHAYLASP.QPFLGYFFMLEDCDASNNPVK..V.R.E.PH.FKVFPEF................VGASYCRRYELFCRKLVLERYYTTSAFITSTASDGSRGLFST---pad...........
T2A1_AZOBR/28-181                .....................QKQQESGKPDQGERRRD-RRKNMDGFCALVIDIIRANGLHRAEIH.QKRALLTLPGYFRPTKLWDLLVIQ.....DRRLVAALEFKSQVGPSFGNNFNNRTEEAIGTAHDLWTAYREGAFGQSP.RPFVGWLMLVEDAPESNQRRA..D.T.S.PH.FRCS---................---------------------------------------------rssrahp.......
F4KTK4_HALH1/26-217              .................aqvt----GSTKADQGNRSAVTGGKQLDGFIELLVKVSEDLGVPKTCIY.--TKGNSLPGYFRPTKDWDFLIIS....pKKQLIAVIEFKSQVG-SFGNNFNNRTEEALGSAVDFWTAFREQGFIQTQ.VPWVGYVILVEKADKSTFPVR..L.Q.E.PY.FNIRPEF................QATSYLDRYALLCQKLMQERHYTATSLIWTN--------------ehfeygalnedi..
E3IT40_DESVR/28-223              .....................EKQLESGKTDQGERAGVTAGKNMDGFVELVLDIVRANGLAHADIH.QNKGLLTLPGFFRPTKLWDLLVIS.....EGQLIAAVEFKSQVGPSFGNNFNNRAEEAIGTAHDFWTAYRDGAFGEQP.RPFIGWLMLVEDAPASRAAVQ..E.C.S.PH.FPVFLEF................KGASYIKRYDILCQKLMHERLYTTASVIASPKNNCRLGQYSSLS-p.............
D4CRF2_9FIRM/27-216              ....................s-RQNASGVHDQGNRGAVTGGKQLDGFVDLIRDILLINGVPRECIF.-TSSDVELPGYYRPNKKWDLLVVD.....NNELVIAIEFKSQVGPSFGNNFNNRTEEAMGGALDIWTAYREGVFGVQK.APWLGYFLVLEDCARSNEPVR..V.R.S.PH.FPVLQEF................VDASYKERYEIFCSKLLLERQYSGACFTTTG--------------vqegrifys.....
Q72WR9_DESVH/28-223              .....................EKQLESGKTDQGERAGVTAGKNMDGFVELVLDIVRANGLAHADIH.QNKGLLTLPGFFRPTKLWDLLVIS.....EGQLIAAVEFKSQVGPSFGNNFNNRAEEAIGTAHDFWTAYRDGAFGEQP.RPFIGWLMLVEDAPASRAAVQ..E.C.S.PH.FPVFLEF................KGASYIKRYDILCQKLMHERLYTTASVIASPKNNCRLGQYSSLS-p.............
A3EW32_9BACT/28-223              .....................QKQIDAGKADQGERGGVTAGKNMDGFVALVIDLIEANGLAHAKIS.RQRAVLTLPGYFRPTKLWDLLVTL.....DGRLIAAVELKSQVGPSFGNNFNNRTEEAIGTAHDLWTAYREGAFGKHP.RPFIGWMMMVEDAPESRRSVA..D.R.S.PH.FPVFKEF................QGASYLKRYDLLCQRLVQEQLYTTASVLASPRSSVNTGEFRDLS-k.............
B7DVE2_9BACL/31-229              ....................s-RQKENGKLDAGTRGAVTGGKQLDGFIELIRWILVQNRVSEHEIF.-TSGRVEIPGFYRPTKRWDIVVVRer.ngRKQLVAAIELKSQVG-SFGKNFNNRTEEAMGNSLDLLTAYRKGAFGDGApPPWLGFIMLLEASPTSMTPVR..V.A.E.SH.FPVFPEF................EYTSYAERYEIFCKKLMLERNYSAAALIMSENREQIDGQYFEPS-p.............
Q8VT53_XANVA/27-222              ...................le---NDEERSQGGERSGVLGGRNMDGFLAMIEGIVRKNGLPDAEVCiKGRPNLTLPGYYRPTKLWDVLVFD.....GKKLVAAVELKSHVGPSFGNNFNNRAEEAIGTAHDLATAIREGILGDQL.PPFTGWLILVEDCEKSKRAVR..D.S.S.PH.FPVFPDF................KGASYLTRYEVLCRKLILEGLYTQATIIASSRTARAGGDYRELSQ..............
D8P7K3_9BACT/180-230             ................dtaah---------------------------------------------.------------------------.....-------------------------------------------------.---------------------..-.-.-.--.----RRY................RGVSYSKRYELLCRRLVLERLYTSACFMMATNSRA----------tkltqpae......
G7GAB8_9GAMM/28-223              ....................l-KQINTGKADQGERAGVTAGKNMDGFLELILEVIQQNGLGHAEIY.QNKAMLTLPGYFRPTKLWDLLVLY.....KGELIAAIELKSQVGPSFGNNFNNRTEEALGTAHDLWTAYREGAFGKQS.RPFVGWLMMVEDAPESRRPVK..D.R.S.PH.FPIFEEF................KNASYLQRYDVLCQRLVQEQLYTNATILASERSADVDGKYSELS-s.............
E6QII0_9ZZZZ/28-221              ..................rqg---AKSGARDAGNRTAVTGGKQLDGFVELVRDYLIECGIEKGDIF.-CNQKVELPGWFRAEKKWDLLVVV.....SGQLVAAMEFKSQVG-SFGNNFNNRTEEVLGSATDIWAAYREGAFSPSQ.RPWLGYLMVLEETHKSLQPVT..V.Q.K.PH.FSVFPEF................DGASYAKRYEILMTKLVRERLYDNAALLLSPSDAAKDGGYLQP--sa............
C2KN83_9ACTO/22-207              .............eqqqlsal-----GGRAQGGTRASVTGGKHLAGVNQLILEELERLGITGLKHY.-TNRQATVPGYYRASKSWDLLVLR.....DDEPALALEYKSMTG-SEGKNLNNRIDEVIGAAQDLHRAQQTGLLPKEL.K--RGYIFLMEVTPAVLNPVG..T.S.T.KV.GTLDPIF................ESTCYLERMAIMCERLRNDGLYGMAWA------------------lgvvrnpig.....
A7IAU1_METB6/21-211              ....................t-KQTESGRHDQGTRGAATGGAQMDAFADLICSAITEAGIPESAIF.-QKTAVELPGYYRPEKKWDIVVVQ.....KGVLGAVIELKSQMGPSFGNNFNNRSEEALGSATDIWVAFREKRFGSRMfRPWLGYLFLLEDCPESTAPVA..V.R.E.PH.FAIDEIF................RDASYKKRYEILCERLILERLYESSCFITAR--------------festdihvd.....
G7WKS3_METH6/13-206              ...................kd--QERRGGSDQGARSAVTGGKQMDGFVRKIIELMTASGVDEGNIY.--TKKTHLPGFFRPVKGWDIVVVV.....DGVLMAAIELKSQVGLSFGNNFNNRTEEAMGTALDIWTAYREGAFCTSP.APWLGYLFLLEDCPESRSPVR..T.Q.E.TH.FPVFEEF................RGASYAKRYELFCRKLVRERQYNAACFIIADREKSN---------sfesyiepa.....
E8MU51_BIFL1/1-145               ....................m---------------------------------------------.-----CTLPGWFRPTKNWDLLALD.....NGELVSAIELKS-INSSFGNNANNRAEESIGSAFDAHTAFDENLLGSSSiPPVMGYVMIVHDCPDSRIVGR.gV.R.S.AH.FPIDPDF................EGASYLDRFLLLCDRLRRKSLYQAVWLVFAN--------------pedgvayepss...
D8P7K3_9BACT/23-186              .....................EKQVKSGKIDAGTRGEVTGGTQMGGLEVLVSDILCEAGLKKVDVR.-TRTALELPGYFRATKKWDLIVVS.....DGALVLAMEFKSQAGKSIGNNVNNRSEEAVGSAKDIWTAFREGRFGTSP.APFLGYLFLLEDRDNVKTPVA..N.K.E.PY.FSVDPEF................RGESHLK--------------------------------------dtaahrr.......
C6E3B4_GEOSM/176-228             ................pdgsy---------------------------------------------.------------------------.....-------------------------------------------------.---------------------..-.-.-.--.----PQA................KGISYIERYDLMCKRLMMKKLYTASAVITSEPGAGLSGSYGHVS-k.............
G4FXS3_9GAMM/60-152              .......reyssallnpviqs---------------------------------------------.------------------------.....----------------------------------------------DPR.PPFLAWLMLLEECDASMRSVR..C.D.E.PH.FPVFEEF................RDASYARRYQILCERLVERQLYSAAALEL----------------tptgkdthralska
T2V1_GEOSE/1-199                 ....................m-NKQASG-KDTGNRGAVTGGKQMDGFADMLTNLLSKVGISNHEVF.-TSEKPHLPGYFRATKKWDFLVVKtndrgEKYLLAAVELKSHVGPSFGNNLNNRVEESLGSATDIWIAFREKAFKNSR.APWLGYLMLLEDCPQSTKPVK..V.D.E.PH.FEVFPEF................KNASYAKRYELFCRKIVLERKYTSSCLLMSDKQGGLQGIYKEPA-n.............
H6SPY2_RHOPH/36-228              ....................a-RQQEGGSRDQGERAGVTAGKNMDAFVDLVTDLVRANGLGDALVH.RQRALLTLPGHFRATKQWDVLIFQ.....EKRLIAALEFKSQAGPSFSSNFNNRCEEAIGTALDLWTACREGAFGPGA.RPFVGWLMLVEDAPGSRAPVR..D.T.C.PH.FPLDPAF................TGASYLERYTVLCQRLMQERLYTAAGVMASPRDTD----------syrdlsp.......
T2P7_PSEAI/28-223                .....................QKQIESGKADQGERAGVTGGKNMDGFLALVLDVIKANGLAHAEIH.QNRAMLTLPGYFRPTKLWDLLVIY.....KGELIAAIELKSHVGPSFSNNFNNRTEEAIGTAHDLWTAYREEAFGKQP.RPFVGWLMMVEDAPESRRPVR..D.S.S.PH.FPVFEEF................KGASYLTRYDLLCQRLVQEQLYTTAAVIAAERSAVDTGNFTELS-s.............
#=GC seq_cons                    .........................tsGctDtGpRuuVTuGKphDGFhtLlh-llptsGlscspla..ppthhsLPGYFRPoKpWDLLVlt.....cGpLlAAlEhKSplGsSFGNNFNNRsEEAlGoAhDlaTAa+EstaGpp..tPalGalhllEDsspSppsV+..s.p.p.PH.Fsl..-F................cGsSYhcRYclhCp+LltEpLYssusllhu.t.t...........s.............
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