GenomeNet

Database: Pfam
Entry: XhoI
LinkDB: XhoI
Original site: XhoI 
#=GF ID   XhoI
#=GF AC   PF04555.12
#=GF DE   Restriction endonuclease XhoI
#=GF AU   Kerrison ND
#=GF SE   DOMO:DM04409;
#=GF GA   25.00 25.00;
#=GF TC   27.40 27.10;
#=GF NC   24.40 24.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   XhoI
#=GF RN   [1]
#=GF RM   3001639
#=GF RT   Nucleotide sequence of the PaeR7 restriction/modification system
#=GF RT   and partial characterization of its protein products. 
#=GF RA   Theriault G, Roy PH, Howard KA, Benner JS, Brooks JE, Waters AF,
#=GF RA   Gingeras TR; 
#=GF RL   Nucleic Acids Res 1985;13:8441-8461.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR007636;
#=GF CC   This family consists of type II restriction enzymes
#=GF CC   (EC:3.1.21.4) that recognise the double-stranded sequence CTCGAG
#=GF CC   and cleave after C-1.
#=GF SQ   61
#=GS A0A0N0Z1C0_9ACTN/24-213  AC A0A0N0Z1C0.1
#=GS A0A0D0VVL1_9ACTN/23-207  AC A0A0D0VVL1.1
#=GS A0A136N1N1_9BACT/25-214  AC A0A136N1N1.1
#=GS A0A0C1VPY4_9ACTN/24-213  AC A0A0C1VPY4.1
#=GS A0A161SC48_9NEIS/29-220  AC A0A161SC48.1
#=GS A0A168JZ92_9ACTN/26-213  AC A0A168JZ92.1
#=GS E8JLP0_9ACTO/28-220      AC E8JLP0.1
#=GS L0DSM3_THIND/1-47        AC L0DSM3.1
#=GS A0A0K2GCR1_9BACT/24-224  AC A0A0K2GCR1.1
#=GS I5B2S0_9DELT/30-220      AC I5B2S0.1
#=GS Q72WR9_DESVH/29-220      AC Q72WR9.1
#=GS W2ERC0_9ACTN/1-68        AC W2ERC0.1
#=GS A7IAU1_METB6/22-209      AC A7IAU1.1
#=GS A0A0W8JIH9_9VIBR/29-220  AC A0A0W8JIH9.1
#=GS A4ALN4_9ACTN/1-71        AC A4ALN4.1
#=GS A0A0Q4IZ49_9SPHN/29-222  AC A0A0Q4IZ49.1
#=GS K9TFW3_9CYAN/28-219      AC K9TFW3.1
#=GS R4YYG9_9ACTN/1-42        AC R4YYG9.1
#=GS G7WKS3_METH6/14-202      AC G7WKS3.1
#=GS A0A0L0K108_9ACTN/23-215  AC A0A0L0K108.1
#=GS A0A0N1LB67_9PROT/30-222  AC A0A0N1LB67.1
#=GS A4ALN1_9ACTN/24-210      AC A4ALN1.1
#=GS H2CG34_9LEPT/27-217      AC H2CG34.1
#=GS A0A0B0EQS0_9BACT/29-219  AC A0A0B0EQS0.1
#=GS E6KUT0_9ACTO/27-215      AC E6KUT0.1
#=GS R5WYQ2_9FIRM/31-219      AC R5WYQ2.1
#=GS A0A109IPZ7_9ACTN/23-210  AC A0A109IPZ7.1
#=GS A0A199NSD0_9MICC/27-214  AC A0A199NSD0.1
#=GS A0A0B0ECZ0_9BACT/1-95    AC A0A0B0ECZ0.1
#=GS A0A0B2AN37_9ACTN/1-167   AC A0A0B2AN37.1
#=GS A0A0B5FRQ3_9DELT/29-220  AC A0A0B5FRQ3.1
#=GS D4CRF2_9FIRM/28-215      AC D4CRF2.1
#=GS A0A143B7N4_9DELT/29-220  AC A0A143B7N4.1
#=GS A0A0S8FA44_9BACT/26-216  AC A0A0S8FA44.1
#=GS U2SB06_9ACTN/23-103      AC U2SB06.1
#=GS Q7N3K6_PHOLL/29-220      AC Q7N3K6.1
#=GS C7M1D1_ACIFD/7-197       AC C7M1D1.1
#=GS R6EHT7_9BACE/21-208      AC R6EHT7.1
#=GS A0A0A0IVW7_9MICO/1-170   AC A0A0A0IVW7.1
#=GS A0A136LCU9_9BACT/33-220  AC A0A136LCU9.1
#=GS G2MQR7_9ARCH/25-214      AC G2MQR7.1
#=GS A0A0H5CTI5_9PSEU/26-216  AC A0A0H5CTI5.1
#=GS A0A176QEW1_9MICO/22-209  AC A0A176QEW1.1
#=GS K5Z1E7_9PROT/29-220      AC K5Z1E7.1
#=GS R6FJH8_9BACE/29-217      AC R6FJH8.1
#=GS A0A0P9D0U9_9BACL/28-223  AC A0A0P9D0U9.1
#=GS A0A126V6N1_9RHOB/29-221  AC A0A126V6N1.1
#=GS M3ELG5_9LEPT/4-78        AC M3ELG5.1
#=GS D5MMJ7_9BACT/31-221      AC D5MMJ7.1
#=GS A0A132BRQ0_9RHOB/29-221  AC A0A132BRQ0.1
#=GS A1WFA1_VEREI/29-125      AC A1WFA1.1
#=GS B3EK31_CHLPB/24-214      AC B3EK31.1
#=GS E0QQ27_9ACTO/23-205      AC E0QQ27.1
#=GS A0A0C9PTJ1_9BACT/31-221  AC A0A0C9PTJ1.1
#=GS A0A101IRL0_9EURY/1-75    AC A0A101IRL0.1
#=GS H6SPY2_RHOPH/37-226      AC H6SPY2.1
#=GS F4KTK4_HALH1/27-214      AC F4KTK4.1
#=GS R6PPH5_9BACT/21-209      AC R6PPH5.1
#=GS A1BHP7_CHLPD/29-219      AC A1BHP7.1
#=GS K9VP54_9CYAN/30-224      AC K9VP54.1
#=GS D8P7K3_9BACT/24-227      AC D8P7K3.1
A0A0N0Z1C0_9ACTN/24-213             .............nqsair-----EAVGAGTAGSVRGGKHFDPVAALLAKFFLEAGYPPESIR..IS..KRqgLE..LPGYYRPQKQWDVVVAY.....EDVLVAAFELKGLGGPSFGNNYNNRVEEALGSAVDLRRAALADLY-PG.EKPWIGYFFIMQDEAESRRPV.K...L.A.K.GA.LPADSIWQ.............G...............ASYQDRFGIFCERLVSEQLYDAVCYVTSSASE--------pkpte......
A0A0D0VVL1_9ACTN/23-207             ...............kkli----DGKIDTGGRGAVTGGAHLNAMTELLGNVFRDAGFPPDAVR..CR..SG..VE..LPGYFRPTKKWDLVVLL.....EGELVAAIELKSHVGPSFGNNFNNRVEEAIGSAADLRRAYDNGLLGR-.TKPWLGYVLLLEEAPGSVSKG.R...P.R.S.GT.FPIDPAFA.............D...............TSYLDRYVILCRRLRSAGLYDATCLVTSSRQ---------pdap.......
A0A136N1N1_9BACT/25-214             ............qgihltp-------KDRGNRAAVTGRKHLDGFIELLNKILFESGLPKTTIH..SD..AT..T-..LPGYYRPTKGWDLVVVS.....EDCLLATIELKSHIGPSFGNNFNNRTEEALGSSADLLTAYREGKFRPS.PKPWMGWFMLLEDCPGSSSPV.R...V.D.E.PY.FDVFPEFK.............Q...............SSYLKRYEILCHRLLRERLYDGVCLLLTRREAGLKGHFTE...........
A0A0C1VPY4_9ACTN/24-213             ...........eqsaikaa-------VGAGTAGSVRGGKHFDPIAVLLSKFFLDAGYPPESIR..VT..KS..QGleLPGYYRPQKQWDLVVVH.....RDTLVAAFELKALGGPSFGNNYNNRVEEALGSAIDLRHAALAELY-PG.EEPWLGYFFIMQDEEGSRRPV.K...P.A.K.GA.LPVEPIWH.............G...............LSYQERFGVFCQRLMSERLYDAACYVTSSSAN--------pkpne......
A0A161SC48_9NEIS/29-220             ...................KQIESGKADQGERAGVTGGKNMDGFLALVLDVIKANGLAHAEIH..QN..RA..ML.tLPGYFRPTKLWDLLVIY.....KGELIAAIELKSHVGPSFSNNFNNRTEEAIGTAHDLWTAYREEAFGKQ.PRPFVGWLMMVEDAPESRRPV.R...D.S.S.PH.FPVFEEFK.............G...............ASYLTRYDLLCQRLVQEQLYTTAAVIAAERSAVDTGNFTE...........
A0A168JZ92_9ACTN/26-213             ................sav----REKVGAGTAGSVRGGKHFDAVAALLAKFFVDAGYPPASIR..VAvgQG..LE..LPGYYRPQKRWDVVVAY.....DNVLVAAFELKALGGPSFGNNYNNRVEEALGSAVDLRRAALAEVYSG-.ERPWLGYFFIMHDEAGSRSGV.R...L.N.K.GP.FPVEGVWQ.............G...............SSYQERFAIFCQRLMAENLYDAVCYVVSSEQD--------prpve......
E8JLP0_9ACTO/28-220                 ..................r-QALRGDADRGGRGQVTAGKNMDGFVHLIHDVADRAGLPKDSVL..VE..RR..AV.tLPGFFRPSKSWDVTVVH.....RGALLAVIEFKSQAGTSMGNNFNNRSEEAVGSAYDLRCAYDEGLLGQI.DPPFIGWFMFVEENSASTRPH.R...D.G.T.QYlFEIDHVMR.............R...............GSYIDRYVELCQRLTATGLYTSCALVSAPASSITSGDFT-v..........
L0DSM3_THIND/1-47                   ..................m--------------------------------------------..--..--..--..-----------------.....------------------------------------------------.---------------------.-...-.-.-.--.---FSEFQ.............G...............ASYPERYNILCQRLMQEQLYSAASIIASARTASADGAYV-e..........
A0A0K2GCR1_9BACT/24-224             ...................KQVQSGKIDAGTRGEVTGGTQMGALEVLVSDILCEAGLKKLDVR..TR..TA..LE..LPGYFRATKKWDLIVVS.....NGALVLAMEFKSQAGKSIGNNVNNRSEEAVGSAKDIWTAFREGRFGPS.PPPFLGYLFLLEDRDNVKTPV.G...N.K.E.PF.FQVDPEFRgealkkkgapryrG...............VSYSKRYELLCRRLVLERLYTSACFLMATNAA--------rttit......
I5B2S0_9DELT/30-220                 ...................KQKKSGKVDYGLRGAVTGGAQMDGFIELFARLIISTGLDAHFIQ..RK..GA..LD..LPGYFRPTKEWDLLVVK.....DGKLIAAIEAKSQVGPSFGNNFNNRTEEAMGSALDLWTAYREGAFHTS.PQPFLGYFFMLEDCQASTRPV.R...V.R.E.PH.FHVFPEFK.............G...............ASYMKRYEIFCRKLVLERHYTASAFITSNRTDGPEGIFS-t..........
Q72WR9_DESVH/29-220                 ...................KQLESGKTDQGERAGVTAGKNMDGFVELVLDIVRANGLAHADIH..QN..KG..LL.tLPGFFRPTKLWDLLVIS.....EGQLIAAVEFKSQVGPSFGNNFNNRAEEAIGTAHDFWTAYRDGAFGEQ.PRPFIGWLMLVEDAPASRAAV.Q...E.C.S.PH.FPVFLEFK.............G...............ASYIKRYDILCQKLMHERLYTTASVIASPKNNCRLGQYS-s..........
W2ERC0_9ACTN/1-68                   ...................--------------------------------------------..--..--..--..-----------------.....------------------------------------------------.-------MFVLQETTETEQEN.R...S.V.D.AL.FPTDPAFK.............G...............MSYNQRYQEMVRRFIGDGIYQAGWFIATKRTE--------egivyne....
A7IAU1_METB6/22-209                 ...................KQTESGRHDQGTRGAATGGAQMDAFADLICSAITEAGIPESAIF..QK..TA..VE..LPGYYRPEKKWDIVVVQ.....KGVLGAVIELKSQMGPSFGNNFNNRSEEALGSATDIWVAFREKRFGSRmFRPWLGYLFLLEDCPESTAPV.A...V.R.E.PH.FAIDEIFR.............D...............ASYKKRYEILCERLILERLYESSCFITARFE---------stdih......
A0A0W8JIH9_9VIBR/29-220             ...................KQIESGNADQGERAGVTAGKNMDGFLALILDVVRANGLSHAEIH..QS..SR..ML.tLPGYFRPTKLWDLLVLY.....KGELIAAVELKSQVGPSFGNNFNNRTEEAIGTAHDLWTAFREEAFGKQ.PRPFVGWLMVVEDAPASRKPV.R...N.A.S.PH.FPVFEEFN.............G...............ASYLKRYDLLCQRLVQERLYTTAAVLTAERSALDTGEFAE...........
A4ALN4_9ACTN/1-71                   ...................---------------------MDGFDTVIAGLVESNARDGAELS..KT..RR..LN.tVPGYFRVMKDRDLLVVR.....KGALVAAIELESQVGPGFGMNFPN------------------------.---------------------.-...-.-.-.--.--------.............-...............----------------------------------------...........
A0A0Q4IZ49_9SPHN/29-222             .................ak--IEAGKIDTGERGAVTAGNTMDGFTALMIDLVEANGLGHAKIY..QQ..RS..VL.tLPGFFRPTKLWDILVIL.....DGRLIAAVEMKSHVGPSFGNNANNRAEEAIGTAHDFWTAYREGAFGADaARPFVGWLVMVEDADKSRRPSkR...E.S.S.LH.FPIFKEFK.............G...............ASYLERYDILCKKLVTENLYTAACVLASPRSAVTTGEYE-d..........
K9TFW3_9CYAN/28-219                 ...................KQKMSIKQDYGARSAVTGGKQMAAFERLATQIALDAGIPESSIF..WT..SR..LE..LPGYFRPEKKWDLLIVD.....QGTLVAAVEFKSQVGPSFGNNFNNRAEEAIGTAQDLWIAYREGVFGEQ.QQPWLGYLFILEDCDKTQVPV.T...A.K.Q.PH.FKVSPDFM.............N...............ASYAKRYEILLTKLVRERYYTSACLILSKKPQN-------iddihyse...
R4YYG9_9ACTN/1-42                   .................ma--------------------------------------------..--..--..--..-----------------.....--------------GNSPGQNYNNRPDSALGQALDAWKAAEREIVDGP.LRPWLG---------------.-...-.-.-.--.--------.............-...............----------------------------------------...........
G7WKS3_METH6/14-202                 ..................d-QERRGGSDQGARSAVTGGKQMDGFVRKIIELMTASGVDEGNIY..TK..KT..H-..LPGFFRPVKGWDIVVVV.....DGVLMAAIELKSQVGLSFGNNFNNRTEEAMGTALDIWTAYREGAFCTS.PAPWLGYLFLLEDCPESRSPV.R...T.Q.E.TH.FPVFEEFR.............G...............ASYAKRYELFCRKLVRERQYNAACFIIADREKSNS-----fesy.......
A0A0L0K108_9ACTN/23-215             ..........neqsaikaa-------VGAGTAGSVRGGKHFDVIATLLAKFFQDAGFPPESIR..AS..KS..QGleLPGYYRPQKQWDLVVVH.....QGVLVAAFEMKALGGPSYSNNYNNRVEEALGSAVDLRRAALAELYP-K.EKPWLGYFFIMQDGEGSRSPV.R...T.A.K.GA.LPSDKIWH.............G...............TSYQDRFGIFCERLMAEQLYDAACYVTSSAEN--------prpielv....
A0A0N1LB67_9PROT/30-222             .................qg--SKSGQKDAGSRGAVTGGKHADGFVNMVADIVRSAGLADPEVRysAK..RG..RT..LPGYFRPSKEWDLVVIS.....RGQLLAAVEIKSQVG-SFGNNFNNRVEEALGNASDFWEAYSKGLYAPS.PEPWLGYLFMLEDADRANAPT.K...R.I.ElDE.FHVDEAFQ.............S...............LSYAQRYEQVCLRLVRERRYQAACFFLSDKSSGKSGKFR-q..........
A4ALN1_9ACTN/24-210                 ...................RQKEEGKKDAGAQAR--NARHMKKLGTFVRQMFVNAGLSEADVM..VN..GV..--..IPGYFRRSKNWDVVATY.....KGQLVALVELKSQVG-SNDSNGNNRIEEALGNPKDAATAQELNQVFGK.LPIWTAFGVVFGSSPENAKAV.G...LpS.N.PL.FPLDPVFN.............G...............MTYGRQWEIAIERFIQTGSYSAGWMVTSWVSA--------egqvkyve...
H2CG34_9LEPT/27-217                 ................kqg--EASGTKDAGNRSSVTGGAQLDGFIELFAKIARDSGLTDSEIH..MK..ET..T-..LPGYYRPTKEWDLVLYA.....DGDLIASVEFKSHIGPSFGNNFNNRVEEALGSATDLRTAYREGAMKQS.IKPWMGYFMLLEDHPKSATPV.K...V.R.E.PY.FPVLPDFK.............E...............ASYQRRYVEFCRRLVLEGLYDSACLLFSAESTGRSGDFTE...........
A0A0B0EQS0_9BACT/29-219             ...................RQKSKGTSDAGLRSAVTGGAQMDGFINLVTKIILDTGIESKYVY..QK..KS..LE..LPGFFRPTKEWDLLVIK.....DGNLVAAVEAKSQVGPSFGNNFNNRTEEAMGTALDLWTAFREGAFNGE.SQPFLGYFFMLEDCEASTRPV.R...V.K.E.PH.FKVFPEFE.............G...............ASYMKRYELFCKKLVRERHYTSASFITSDSVNGVNGIYM-e..........
E6KUT0_9ACTO/27-215                 ..............nqggl----SGIKDTGNRAAVTGGKQMDLMQAVVADLWMSDPEIHLEVR..TT..GH..ND..LPTYFRPSKNWDLVVLY.....RGALIAAMEFKSQRGPSFGNNFNNRTEEALGLAADSQMAVERGLFGI-.LKPWFGFIMLVERAVGSTRPV.R...V.PpN.MP.FPADPIFH.............G...............KSYIGRYRIFFERMIAEGNYDAVALLTAEANSGE------yqe........
R5WYQ2_9FIRM/31-219                 ...................KQDNSAVHDQGNRGAVTGGKQLDGFVDLISEILIMNGVPKTSIF..TS..SN..LE..LPGFYRPNKKWDLLVVD.....NNELVIAIEFKSQVGPSFGNNFNNRTEEAMGSALDIWTAYREGVFGSQ.NAPWLGYFMVLEDCKKSTDPV.N...V.R.S.PH.FQVLDEFI.............D...............ASYKDRYQIFCNKLLLERQYSAACFMTTSKGEN-------tnsya......
A0A109IPZ7_9ACTN/23-210             .................kk--VLSGRTDTGLRGAVTGGGHLDAITELLADVFRAAGFAPDAVR..CK..SG..VT..LPGYFRAAKKWDLVVIH.....EGALVAAIELKSHFGPSFGNNSNNRSEEAVGSAVDLRQAYDHGLLG-A.VRPWLGYLLLVEEEPRSLRRS.T...P.R.S.GT.FPVDPAFG.............E...............TSYLDRYVLLCKRLRNAGLYDATCLLASSREG--------dafvrq.....
A0A199NSD0_9MICC/27-214             ...............kqge---ATGIKDTGNRAAVTGGKQMDAMQEAVAAIWRNDPDITLEVR..TT..GH..NN..LPAYFRPAKNWDLVVLY.....RGSLIAAMEFKSQRGPSFGNNYNNRTEEALGLSADSQMAVERGLFGR-.LKPWFGFIMLVERTIGSLSPV.K...VpK.N.MP.FPVDRIFE.............G...............ASYIDRYRIFFERMVAEGNYDAAALLTAEA----------ggdtyv.....
A0A0B0ECZ0_9BACT/1-95               ...................--------------------------------------------..--..--..--..-----------------.....-----------------------------MGTALDLWTAFREGVFKGD.TQPFLGYFFMLEDCEASTRPV.R...V.K.E.PH.FKVFPEFE.............G...............ASYMKRYELFCKKLVRERHYTSASFITSESVNGVNGIYK-e..........
A0A0B2AN37_9ACTN/1-167              mdamqevvaklwrddpdit----------------------------------------LEVR..TT..GH..NN..LPAYFRPAKNWDLLVLY.....RGSLIAAMEFKSQRGPSFGNNFNNRTEEALGLAADSQMAVERGLFGQ-.LKPWFGFIMLVERAPGSLSAV.K...VpK.N.MP.FPADPIFE.............G...............ASYIGRYKIFFERMVKEGNYDAVALLTAES----------gsehfte....
A0A0B5FRQ3_9DELT/29-220             ...................KQIESGKADQGERASVTSGKNMDGFIALILDIIHANGLTHADIH..QK..RA..VL.tLPGFFRPTKLWDLLVIH.....KGELIAAIELKSQVGPSFGNNFNNRTEEAIGTAHDLWTAYREGAFGKQ.PRPFVGWLMLVEDAPESRSPV.K...Y.N.S.PH.FPVFKEFK.............S...............VSYLQRYDLLCQKLTQEQLYTSASLIASPRSAAAGGNFC-s..........
D4CRF2_9FIRM/28-215                 ...................RQNASGVHDQGNRGAVTGGKQLDGFVDLIRDILLINGVPRECIF..TS..SD..VE..LPGYYRPNKKWDLLVVD.....NNELVIAIEFKSQVGPSFGNNFNNRTEEAMGGALDIWTAYREGVFGVQ.KAPWLGYFLVLEDCARSNEPV.R...V.R.S.PH.FPVLQEFV.............D...............ASYKERYEIFCSKLLLERQYSGACFTTTGVQE--------grify......
A0A143B7N4_9DELT/29-220             ...................KQIESGKSDQGERAGVTAGKNMDGFIALILDVIRANGLANADIH..QK..RA..VL.tLPGFFRPTKLWDLLVIH.....KGELIAAIELKSQVGPSFGNNFNNRTEEAIGTAHDLWTAYREGAFGKQ.PRPFVGWLMLVEEALESSSSI.K...D.N.S.PH.FPVFEEFK.............G...............ASYLQRYDLLCQKLTQEQLYTTASLIASPRTAAGNGEFS-s..........
A0A0S8FA44_9BACT/26-216             ...................RQQEGGRTDRGGRSAVTGGAQMDGFARLLADLVTDAGVPEATVY..GK..RR..LE..LPGFFRPTKEWDLLVVH.....EGRLLVAVEVKAQVGPSFGNNFNNRVEEALGSAVDLWTAYREGVFSPS.PRPWLGYLMLLEDCAGSRSPV.A...V.R.Q.PH.FATLPEFQ.............E...............ASYAGRYEQFCLKIVRERHYDAAAFIISKRPEGEG-----vlyte......
U2SB06_9ACTN/23-103                 .............qqelse---ATGRAQGGARAAVTGGRHLAGVNRLIVEELQDLGLTGHTCC..TD..RR..AT..APGYHRVSKSWDPLVLN.....NG----------------------------------------------.---------------------.-...-.-.-.--.--------.............-...............----------------------------------------ipdschrvq..
Q7N3K6_PHOLL/29-220                 ...................KQIESGKADQGERAGVTAGKNMDGFLALVLDIIKANGLAHAEIH..QN..RA..ML.tLPGYFRPTKLWDLLVLY.....KGQLIAAIELKSQVGPSFGNNFNNRTEEAIGTAHDLWTAFREEAFGKQ.PRPFVGWMMMVEDASESRKSV.R...D.S.S.PH.FPVFEEFK.............G...............ASYLKRYDLLCQRLVQEQLYTTAAVIAAERSAVNTGDFAE...........
C7M1D1_ACIFD/7-197                  ...........qtvkqmgg--------SAGTRGAVTGGAQMGALEVLLTDVLVDAGLEPDHVR..VR..TA..LE..LPGYYRPERKWDLLVVV.....DGQLLVAVEFKSQVGPSFGNNFNNRTEEAIGNAEDIWTAYREGRFGKH.PAPFLGYFFLLEDCAKVHAPV.R...N.V.E.PY.FPVDPIFA.............G...............ASYAKRYEVLCDRLVLERKYSAGCLTLATNSKPTKVT---fps........
R6EHT7_9BACE/21-208                 ...............kqkq---LSASNESSNRGAVVGGKQLDAFADLLRTIAIEQGVPEACIY..TK..QA..Y-..LPGYFRSSKDWDFLIIA....pNKKLIAAIELKSQIG-SYGNNLNNRAEEAIGSAVDLWTAFRENQFPDQ.TAPWIGYLTIVGKDEKSTCAI.R...N.N.E.PH.YSVLPEFK.............N...............ASYLDRYRILCQKLILERHYSMAALICTS-----------gpdhfedi...
A0A0A0IVW7_9MICO/1-170              .................mq-----------------------SMATFVRQMFIDAGLDSSDVV..LD..RA..V-..-PGFYRRSKEWDVVAMR.....KGHLVGVVELKSQES-SPGNNANNRLEEAVGSAVDAHTVQDYSGVYGD.LGVWAAWCMTFNANCETGAPV.GykfN.R.A.PL.FSVDPEFE.............P...............MTYASQYEIAVQRFIATNVYNAAWMLTTW-----------inadssigyye
A0A136LCU9_9BACT/33-220             ...................KQRESGKSDQGLRGAATGGAQMDGFIGVLVETTLLCGFAETEIH..FK..KA..IE..LPGYFRPTKEWDLLVVS.....KGRLLVAMETKSQVGPSFGNNFNNRTEEAMGSALDLWTAYREGRFGGG.VQPWLGYFFLLEDCAQSRTPV.K...V.R.E.PH.FEVFPEFQ.............G...............ASYAKRYELFCRKLKLERQYSQTALLLSKAD---------trgyse.....
G2MQR7_9ARCH/25-214                 ...................EQQESEDAARGRRAEVLGGRQLDGFATVCEEILMEAGVPEKSIY..FD..HE..AT..LPGFFRATKRWDLAVIH.....EGELLAAIEFKS-ITSSFGNNLNNRTEEALGSPTDLYTAYEEGAYDPS.PRPWLGYLMLMSENGNSTGSV.R...V.S.E.PH.FDVLEEFD.............G...............ASYVDRGEQLCLRLLRQRLYDGCVFLLSDAEGGLDGEFWE...........
A0A0H5CTI5_9PSEU/26-216             .............srikaa-------VGAGTAGSVRGGKHFDPIALLLAKFFLDAGYPTESIR..IEagHG..LE..LPGYFRPSKRWDLVVAH.....KGTLVAAFELKALGGPSFGNNYNNRMEEALGTATDARHAIMADLFP-G.EVPWLGFFLIVEDDFRSRRPV.S...L.AtK.GA.FPMDPAWV.............G...............LSYMERSALSCDRFVREKLYDAVCCIASSP----------depipvefd..
A0A176QEW1_9MICO/22-209             ....qrlaaagrsntgaqa----------------RDAMHMQSMASFVRQMFIDAGLDPHDVL..LD..HS..V-..-PGFYRRSKEWDVVAMR.....RGHLVGVVELKSQES-SPGNNANNRIEEAVGSAVDAHTFQEYSGLYGD.LGVWAAWCMTFNLNCEGGSPI.GykfN.R.V.PL.FPVDQEFE.............P...............MTYASQYATAIQRFIATNVYNAAWMLTT------------wvnpdksigy.
K5Z1E7_9PROT/29-220                 ...................KQIESGKADQGERAGVTAGKNMDGFLALVLDIIKANGLAHAEFY..QN..RA..ML.tLPGYFRPTKLWDLLVIY.....KNELIAAVELKSHVGPSFGNNFNNRTEEAIGTAHDLWTAFREEAFGKQ.PRPFVGWLMMVEDAPESRRAV.K...D.S.S.PH.FPVFEEFK.............G...............ASYLKRYDLLCQRLVQEQLYTTAAVIAAERSAVNTGHFTE...........
R6FJH8_9BACE/29-217                 ..................s-QLDRNNRDTGNRGAVTGGKQMDGFVDLLAKVATDMGVPQNCIY..TK..RN..Q-..LPGYFRPTKDWDFLIVS....pTNKLIAAIEFKSQVG-SFGNNFNNRTEEALGSAVDLWTAFRENVFPNQ.NAPWVGYLMAVERCKKSTSII.R...V.T.E.PH.FKVLEEFK.............E...............TSYIDRYAILCRKLILERHYTATALLWTSDS---------stygdvas...
A0A0P9D0U9_9BACL/28-223             ................knm---DRGVQNQGTRGAVTGGKQLDGFLEVLRWILLKNGVTEDEIF..TS..GK..LE..LPGFYRPSKQWDLVVVRqqqsgEKRLIAAVELKSQVG-SFGNNFNNRTEEAMGSSLDILTAYREGAFGDSaPSPWLGYLMVLEESPKSTVPV.R...V.A.E.PH.FNVFEEFR.............D...............TSYAQRYELFCKKLLLERNYTAAAFLMSNKSFGPEGNYG-e..........
A0A126V6N1_9RHOB/29-221             ...................KQTDAGNQDAGARGAVTAGKNLDGFVAMVQSLVEANELWDAEIC..VR..KR..SL.vLPGFYRPTKEWDMLILR.....RGELVAALEFKSQVGPSFGNNFNNRSEEVMGSAHDMWTAYREGAFGEDtSRPFLGWLMLVEECDASTSPV.K...V.S.E.PH.FHVDPVFR.............G...............ASYIERYDILCKRLVQEGLYNSAALLASPREAAADGQFR-h..........
M3ELG5_9LEPT/4-78                   ........nlnhgwviftf--------------------------------------------..--..--..--..-----------------.....------------------------------------------------.-----------RIPSESLSPV.K...N.R.E.PY.FKTSKEFH.............N...............TSYTDRYKEFCKRLVRERLYDSSCLLIANSDQGSK-----eplk.......
D5MMJ7_9BACT/31-221                 ...................RQKQTGKADQGLRSAVTGGAQMDGFIDLFTELITAAGIPARYIF..RS..KD..VE..LPGFFRPTKEWDLLVIR.....EKTLLIAIEAKSQVGPSFGNNFNNRTEEAMGSALDLWTAYREHAYLAS.PQPFLGYFFMLEDCDASNNPV.K...V.R.E.PH.FKVFPEFV.............G...............ASYCRRYELFCRKLVLERYYTTSAFITSTASDGSRGLFS-t..........
A0A132BRQ0_9RHOB/29-221             ...................KQIESGNQDAGARGAVTAGKNMDGFLAIAQTLIEANGLGLADIC..VK..QR..VL.tLPGFFRPTKLWDMLVVN.....KGELVAALEFKSQVGPSFGNNFNNRSEEAIGTAHDLWTAYREGAFGEDaPRPFLGWVMLVEDCPKSNTPV.G...D.K.Q.PH.FPVDPAFK.............G...............ASYTQRYDILCKRLVQEGLYSSAAFLSSPRDAGADGRYR-h..........
A1WFA1_VEREI/29-125                 ...................KQKESGKADQGERAAVTGGKNMHGVSRLVVDLVKANGLPNAQVH..QQ..RA..VL.tLPGYFRPTKLWDLLVID.....NGRLIAAVEFKSHVGPSFGNDFNNRT----------------------.---------------------.-...-.-.-.--.--------.............-...............----------------------------------------gsp........
B3EK31_CHLPB/24-214                 ................kqg--SSTGKKDAGNRSAVTGGKHLDGFIKLLTELLAEAGLPDSAIH..VK..ST..T-..LPGYFRPTKNWDLLVVV.....DRILLASIELKAHIGPSFGNNFNNRVEEALGNSTDLLTAYREGKFKPS.QKPWLGWLMLLEDAPKSTTPV.R...V.D.E.PH.FEVFPEFK.............E...............ASYAKRYGLFCERLMRERLYDGACLIMSDKAGGLKGKFTE...........
E0QQ27_9ACTO/23-205                 ...........qqqlsalg-----GRAQGGTRASVTGGKHLAGVNQLILEELERLGITGLKHY..TN..RQ..AT..VPGYYRASKSWDLLVLR.....DDEPALALEYKSMTG-SEGKNLNNRIDEVIGAAQDLHRAQQTGLLPKE.LK--RGYIFLMEVTPAVLNPV.G...T.S.T.KV.GTLDPIFE.............S...............TCYLERMAIMCERLRNDGLYGMA-----------------walgvvrnp..
A0A0C9PTJ1_9BACT/31-221             ...................KQEQAGKADQGLRSAVTGGAQMNGFIDLFTKLVTQSGIPERYVF..RK..KA..IE..LPGFFRPTKEWDLLVVR.....ERTLIAAVEAKSQVGPSFGNNFNNRTEEAMGSALDLWTAYREHAYLDS.PQPFLGYFFMLEDCTASNRPV.S...I.Q.E.PH.FKVFPEFR.............G...............ASYMRRYELFCRKLVLERHYTASAFITSSSHEGLKGIFK-t..........
A0A101IRL0_9EURY/1-75               ...................--------------------------------------------..--..--..--..-----------------.....------------------------------------------------.--PWLGYMLLLEDCEKSRKSV.R...N.N.E.PH.FEVFPEFN.............E...............ASYVERYHQTCLKLVRERVYSEVCYLLAREANKM------qprnyse....
H6SPY2_RHOPH/37-226                 ...................RQQEGGSRDQGERAGVTAGKNMDAFVDLVTDLVRANGLGDALVH..RQ..RA..LL.tLPGHFRATKQWDVLIFQ.....EKRLIAALEFKSQAGPSFSSNFNNRCEEAIGTALDLWTACREGAFGPG.ARPFVGWLMLVEDAPGSRAPV.R...D.T.C.PH.FPLDPAFT.............G...............ASYLERYTVLCQRLMQERLYTAAGVMASPRDT--------dsyrdl.....
F4KTK4_HALH1/27-214                 ...............qvtg----STKADQGNRSAVTGGKQLDGFIELLVKVSEDLGVPKTCIY..TK..GN..S-..LPGYFRPTKDWDFLIIS....pKKQLIAVIEFKSQVG-SFGNNFNNRTEEALGSAVDFWTAFREQGFIQT.QVPWVGYVILVEKADKSTFPV.R...L.Q.E.PY.FNIRPEFQ.............A...............TSYLDRYALLCQKLMQERHYTATSLIWTNE----------hfeygaln...
R6PPH5_9BACT/21-209                 ................knq---LAHSTDKSNRGAVTGGKQLDGFIVILKKLALSAGVKRNCIF..TK..NN..Y-..LPGYFRSSKDWDFVILT....pSRKLLVAIELKSQIG-SYGNNFNNRTEEALGSAVDFWTAFRKDQFPHQ.EAPWLGYLMIVGKDEKSTVSV.K...N.Y.E.NH.FPVREEFH.............G...............TSYLERYKILCQKLIQERHYTSTALLWTNDK---------edfgdveg...
A1BHP7_CHLPD/29-219                 ...................KQLLTGKADHGERAGVTAGKNMDGFLALVLDIIQANGLAHAEIH..QN..RS..ML.tLPGYFRPTKLWDLLVIY.....KGELIAAIELKSQVG-SFGNNFNNRTEEAIGTAYDLWTAYREEAFGKQ.PRPFVGWLMMVEDAPKSRCAV.R...D.A.S.PH.FPVFGEFE.............G...............ASYLMRYDLLCQKLVKEQLYTTAALITSTRCAAETGEFSE...........
K9VP54_9CYAN/30-224                 ..................a-QVLAGKVDQGNRSAVTGGKQMDGFILTLTNFLLAAGVPQNHIH..VK..KS..LT.vIPGFFRPAKMYDFLVVNp...eKRQLKVVIELKSQVG-SFGNNFNNRTEEAMGAALDIWTAYREGVFGEApPPPWLGYLFVLEDSPASRTRV.Q...V.A.E.PH.FAVLPEFR.............G...............ASYAKRYELFCQKMVRERHFTAACFLVTDREQVAQ-----tpnyte.....
D8P7K3_9BACT/24-227                 ...................KQVKSGKIDAGTRGEVTGGTQMGGLEVLVSDILCEAGLKKVDVR..TR..TA..LE..LPGYFRATKKWDLIVVS.....DGALVLAMEFKSQAGKSIGNNVNNRSEEAVGSAKDIWTAFREGRFGTS.PAPFLGYLFLLEDRDNVKTPV.A...N.K.E.PY.FSVDPEFR.............GeshlkdtaahrryrgVSYSKRYELLCRRLVLERLYTSACFMMATNSRAT------kltq.......
#=GC seq_cons                       .......................sGptDtGtRuuVTGG+phDuhhtLltclhhssGlspsplh..tp..ps..h...LPGaFRPoKpWDLlVlp.....cGpLlAAlEhKSQlGPSFGNNFNNRsEEAlGoAhDlaTAac-shFstp..pPalGahhllE-sstSppPV.+...s.p.p.Pa.FsV..-Fc.............u...............uSYhcRYclhCp+LltEphYsuushlsosppt...................
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