GenomeNet

Database: Pfam
Entry: YSIRK_signal
LinkDB: YSIRK_signal
Original site: YSIRK_signal 
#=GF ID   YSIRK_signal
#=GF AC   PF04650.14
#=GF DE   YSIRK type signal peptide
#=GF AU   Bateman A
#=GF SE   Pfam-B_3441 (release 7.5)
#=GF GA   20.00 20.00;
#=GF TC   20.10 20.10;
#=GF NC   19.60 19.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Motif
#=GF DR   INTERPRO; IPR005877;
#=GF CC   Many surface proteins found in Streptococcus, Staphylococcus,
#=GF CC   and related lineages share apparently homologous signal
#=GF CC   sequences. A motif resembling [YF]SIRKxxxGxxS[VIA] appears at
#=GF CC   the start of the transmembrane domain. The GxxS motif appears
#=GF CC   perfectly conserved, suggesting a specific function and not just
#=GF CC   homology.  There is a strong correlation between proteins
#=GF CC   carrying this region at the N-terminus and those carrying the
#=GF CC   Gram-positive anchor domain with the LPXTG sortase processing
#=GF CC   site at the C-terminus.
#=GF SQ   207
#=GS D6S364_9LACO/13-38      AC D6S364.1
#=GS E8SI63_STAPH/5-29       AC E8SI63.1
#=GS A0A089ZKL4_9LACO/19-43  AC A0A089ZKL4.1
#=GS B9DLE5_STACT/7-31       AC B9DLE5.1
#=GS Q8E1G3_STRA5/5-26       AC Q8E1G3.1
#=GS Q8DRK2_STRR6/7-32       AC Q8DRK2.1
#=GS E8JY21_9STRE/7-31       AC E8JY21.1
#=GS LIP_STAEQ/4-28          AC Q5HKP6.1
#=GS A8AYA5_STRGC/7-32       AC A8AYA5.1
#=GS E8K195_9STRE/6-25       AC E8K195.1
#=GS U2KGC7_9STRE/9-33       AC U2KGC7.1
#=GS Q8DRA6_STRR6/9-34       AC Q8DRA6.1
#=GS Q8DUW9_STRMU/4-28       AC Q8DUW9.1
#=GS C0MCG2_STRS7/9-33       AC C0MCG2.1
#=GS T0TGF4_9STRE/2-26       AC T0TGF4.1
#=GS Q9A180_STRP1/2-27       AC Q9A180.1
#=GS S1N500_9ENTE/12-37      AC S1N500.1
#=GS E8K2T7_9STRE/33-58      AC E8K2T7.1
#=GS E3C5V5_9LACO/17-41      AC E3C5V5.1
#=GS Q5HS21_STAEQ/5-29       AC Q5HS21.1
#=GS Q8E1C4_STRA5/14-39      AC Q8E1C4.1
#=GS Q5HNF3_STAEQ/4-29       AC Q5HNF3.1
#=GS Q74KU3_LACJO/9-34       AC Q74KU3.1
#=GS E8JXU1_9STRE/7-32       AC E8JXU1.1
#=GS E3C7Z7_9LACO/16-41      AC E3C7Z7.1
#=GS Q8CVC7_STRMU/10-33      AC Q8CVC7.1
#=GS T0U0E6_9ENTE/16-41      AC T0U0E6.1
#=GS E8K2U6_9STRE/7-31       AC E8K2U6.1
#=GS A0A089Y697_9LACO/19-43  AC A0A089Y697.1
#=GS Q8DYX2_STRA5/9-34       AC Q8DYX2.1
#=GS A8YUX0_LACH4/17-41      AC A8YUX0.1
#=GS A4VUD0_STRSY/18-43      AC A4VUD0.1
#=GS V4QYE3_STRIN/2-26       AC V4QYE3.1
#=GS A8AVB1_STRGC/5-29       AC A8AVB1.1
#=GS C0MF89_STRS7/5-30       AC C0MF89.1
#=GS B9DJ62_STACT/10-34      AC B9DJ62.1
#=GS A4VVP2_STRSY/7-32       AC A4VVP2.1
#=GS Q5FJA7_LACAC/16-39      AC Q5FJA7.1
#=GS G5KEA1_9STRE/13-37      AC G5KEA1.1
#=GS NANA_STRR6/22-47        AC P62576.1
#=GS E8SH04_STAPH/4-28       AC E8SH04.1
#=GS F2I4G0_AERUA/16-41      AC F2I4G0.1
#=GS E8SGC5_STAPH/14-39      AC E8SGC5.1
#=GS T0TJI2_9STRE/6-31       AC T0TJI2.1
#=GS A8AUR8_STRGC/5-29       AC A8AUR8.1
#=GS Q2FW95_STAA8/4-28       AC Q2FW95.1
#=GS Q5FJC1_LACAC/14-39      AC Q5FJC1.1
#=GS E8K102_9STRE/14-39      AC E8K102.1
#=GS Q99XV2_STRP1/7-32       AC Q99XV2.1
#=GS U2KNJ2_9STRE/8-32       AC U2KNJ2.1
#=GS T0V7L8_9STRE/6-27       AC T0V7L8.1
#=GS A8AWJ3_STRGC/9-33       AC A8AWJ3.1
#=GS A0A089Y066_9LACO/19-42  AC A0A089Y066.1
#=GS UAFA_STAS1/15-40        AC Q4A0V8.1
#=GS IGA1_STRR6/7-32         AC Q59947.2
#=GS K1LN60_9LACT/2-27       AC K1LN60.1
#=GS E3C831_9LACO/16-41      AC E3C831.1
#=GS B2GBF6_LACF3/16-41      AC B2GBF6.1
#=GS T0V9D9_9STRE/7-32       AC T0V9D9.1
#=GS Q74I86_LACJO/5-28       AC Q74I86.1
#=GS Q99XV0_STRP1/5-30       AC Q99XV0.1
#=GS Q74L43_LACJO/11-36      AC Q74L43.1
#=GS E8SG89_STAPH/3-27       AC E8SG89.1
#=GS A4VSS5_STRSY/5-30       AC A4VSS5.1
#=GS B9DSF3_STRU0/11-34      AC B9DSF3.1
#=GS U2JEM9_9STRE/6-30       AC U2JEM9.1
#=GS A5VKZ2_LACRD/16-40      AC A5VKZ2.1
#=GS V4SHT8_STRIN/14-38      AC V4SHT8.1
#=GS Q2FXH4_STAA8/5-29       AC Q2FXH4.1
#=GS C0MEV6_STRS7/7-31       AC C0MEV6.1
#=GS E3C8Y6_9LACO/14-37      AC E3C8Y6.1
#=GS Q5FIM7_LACAC/17-40      AC Q5FIM7.1
#=GS B9DIB2_STACT/18-42      AC B9DIB2.1
#=GS E8K154_9STRE/7-32       AC E8K154.1
#=GS Q8CYI8_STRR6/15-38      AC Q8CYI8.1
#=GS E8JXS9_9STRE/19-44      AC E8JXS9.1
#=GS Q74JH9_LACJO/16-39      AC Q74JH9.1
#=GS LIP1_STAA8/2-27         AC Q2FUU5.1
#=GS CLFA_STAA8/4-27         AC Q2G015.1
#=GS B9EAH6_MACCJ/2-27       AC B9EAH6.1
#=GS GH101_STRR6/7-32        AC Q8DR60.1
#=GS Q8DYZ1_STRA5/8-32       AC Q8DYZ1.1
#=GS A8AVB4_STRGC/9-34       AC A8AVB4.1
#=GS E8SES1_STAPH/11-35      AC E8SES1.1
#=GS T0TXW9_9STRE/9-34       AC T0TXW9.1
#=GS B9DKE9_STACT/2-27       AC B9DKE9.1
#=GS B0S0B2_FINM2/20-43      AC B0S0B2.1
#=GS Q5FIF3_LACAC/5-29       AC Q5FIF3.1
#=GS A4VXV9_STRSY/9-32       AC A4VXV9.1
#=GS E3C782_9LACO/16-41      AC E3C782.1
#=GS Q5FJS0_LACAC/14-38      AC Q5FJS0.1
#=GS G5KE73_9STRE/10-34      AC G5KE73.1
#=GS C8PDF1_9LACO/25-48      AC C8PDF1.1
#=GS D6S5D7_9LACO/16-41      AC D6S5D7.1
#=GS E8K103_9STRE/7-32       AC E8K103.1
#=GS C8PC76_9LACO/18-42      AC C8PC76.1
#=GS F6CB75_LACKZ/14-39      AC F6CB75.1
#=GS B9DPH4_STACT/9-34       AC B9DPH4.1
#=GS E3C7W1_9LACO/16-41      AC E3C7W1.1
#=GS Q5HKF4_STAEQ/10-35      AC Q5HKF4.1
#=GS U2IJA8_9STRE/4-29       AC U2IJA8.1
#=GS B0S330_FINM2/20-43      AC B0S330.1
#=GS B9DIH4_STACT/3-27       AC B9DIH4.1
#=GS CLFB_STAA8/10-35        AC Q2FUY2.1
#=GS A8AV25_STRGC/4-28       AC A8AV25.1
#=GS SASG_STAA8/17-42        AC Q2G2B2.1
#=GS G5KDY8_9STRE/15-39      AC G5KDY8.1
#=GS C0MH02_STRS7/11-34      AC C0MH02.1
#=GS E8JY07_9STRE/90-114     AC E8JY07.1
#=GS E3C756_9LACO/17-40      AC E3C756.1
#=GS SPA_STAA8/2-26          AC P02976.3
#=GS A4VXP9_STRSY/7-32       AC A4VXP9.1
#=GS A8AXC5_STRGC/9-33       AC A8AXC5.1
#=GS E3C6I4_9LACO/16-41      AC E3C6I4.1
#=GS C8PBR2_9LACO/20-45      AC C8PBR2.1
#=GS E3C835_9LACO/19-41      AC E3C835.1
#=GS C8PC75_9LACO/16-41      AC C8PC75.1
#=GS V4Q7I6_STRIN/15-40      AC V4Q7I6.1
#=GS Q1WSI9_LACS1/12-37      AC Q1WSI9.1
#=GS PFBA_STRR6/18-41        AC Q8CYC9.1
#=GS F2I4F9_AERUA/16-41      AC F2I4F9.1
#=GS B9DJS1_STACT/16-39      AC B9DJS1.1
#=GS A8AWS3_STRGC/8-32       AC A8AWS3.1
#=GS ISDB_STAA8/7-32         AC Q2FZF0.1
#=GS T1ZFU6_STRIT/11-35      AC T1ZFU6.1
#=GS D6S3U4_9LACO/17-42      AC D6S3U4.1
#=GS D6S4F2_9LACO/17-42      AC D6S4F2.1
#=GS D6S602_9LACO/6-30       AC D6S602.1
#=GS Q8DX06_STRA5/2-27       AC Q8DX06.1
#=GS T1ZFN2_STRIT/2-25       AC T1ZFN2.1
#=GS EBH_STAA8/5-30          AC Q2FYJ6.1
#=GS D6S587_9LACO/12-36      AC D6S587.1
#=GS T0TTB0_9STRE/4-26       AC T0TTB0.1
#=GS D6S6B2_9LACO/16-40      AC D6S6B2.1
#=GS E8JYZ6_9STRE/4-27       AC E8JYZ6.1
#=GS FNBA_STAA8/2-27         AC P14738.1
#=GS Q5HKK8_STAEQ/3-27       AC Q5HKK8.1
#=GS F6CDG4_LACKZ/17-40      AC F6CDG4.1
#=GS Q8CZ52_STRR6/7-31       AC Q8CZ52.1
#=GS Q5HS13_STAEQ/18-43      AC Q5HS13.1
#=GS E3C608_9LACO/11-34      AC E3C608.1
#=GS A4VY42_STRSY/39-64      AC A4VY42.1
#=GS Q5HKE8_STAEQ/18-43      AC Q5HKE8.1
#=GS Q74LY6_LACJO/16-40      AC Q74LY6.1
#=GS V4QT53_STRIN/4-27       AC V4QT53.1
#=GS K1LKR4_9LACT/16-36      AC K1LKR4.1
#=GS R5QBG6_9FIRM/17-42      AC R5QBG6.1
#=GS Q5FKA5_LACAC/16-39      AC Q5FKA5.1
#=GS D6S603_9LACO/6-30       AC D6S603.1
#=GS E3C671_9LACO/10-35      AC E3C671.1
#=GS Q8DZ94_STRA5/9-34       AC Q8DZ94.1
#=GS Q74HP2_LACJO/17-41      AC Q74HP2.1
#=GS E8JYK9_9STRE/7-32       AC E8JYK9.1
#=GS K1MH12_9LACT/16-41      AC K1MH12.1
#=GS Q8DQP4_STRR6/7-32       AC Q8DQP4.1
#=GS Q5HKF8_STAEQ/5-30       AC Q5HKF8.1
#=GS V4R195_STRIN/10-35      AC V4R195.1
#=GS T0TXM2_9STRE/7-32       AC T0TXM2.1
#=GS SDRD_STAA8/18-43        AC Q2G0L4.1
#=GS Q5M5L4_STRT2/16-40      AC Q5M5L4.1
#=GS C8PD26_9LACO/16-41      AC C8PD26.1
#=GS Q74HU0_LACJO/3-28       AC Q74HU0.1
#=GS A8AVS2_STRGC/2-27       AC A8AVS2.1
#=GS K1LBH0_9LACT/17-41      AC K1LBH0.1
#=GS Q5HQ38_STAEQ/14-38      AC Q5HQ38.1
#=GS A8AXF9_STRGC/7-32       AC A8AXF9.1
#=GS A0A089Y475_9LACO/18-43  AC A0A089Y475.1
#=GS LIP2_STAA8/5-30         AC Q2G155.1
#=GS A4VSQ8_STRSY/9-33       AC A4VSQ8.1
#=GS Q5FIP7_LACAC/16-39      AC Q5FIP7.1
#=GS F6CG01_LACKZ/14-39      AC F6CG01.1
#=GS K1LN36_9LACT/16-41      AC K1LN36.1
#=GS F2I830_AERUA/17-41      AC F2I830.1
#=GS Q74HA8_LACJO/24-48      AC Q74HA8.1
#=GS Q8DN05_STRR6/7-32       AC Q8DN05.1
#=GS A0A088A2X1_APIME/29-53  AC A0A088A2X1.1
#=GS E8K213_9STRE/4-27       AC E8K213.1
#=GS E8SH87_STAPH/4-28       AC E8SH87.1
#=GS C8PC68_9LACO/27-52      AC C8PC68.1
#=GS D6S4X0_9LACO/18-42      AC D6S4X0.1
#=GS C8PCN3_9LACO/16-41      AC C8PCN3.1
#=GS T0UTD1_9STRE/2-27       AC T0UTD1.1
#=GS ISDH_STAA8/8-31         AC Q2FXJ2.1
#=GS U2JEU0_9STRE/5-29       AC U2JEU0.1
#=GS C0MDN4_STRS7/2-26       AC C0MDN4.1
#=GS Q5FKA6_LACAC/16-39      AC Q5FKA6.1
#=GS K1LF19_9LACT/16-41      AC K1LF19.1
#=GS E8SG87_STAPH/3-27       AC E8SG87.1
#=GS C8PBR3_9LACO/4-27       AC C8PBR3.1
#=GS E3C6Y5_9LACO/22-39      AC E3C6Y5.1
#=GS E8JZ10_9STRE/9-34       AC E8JZ10.1
#=GS T0V184_9STRE/10-31      AC T0V184.1
#=GS SDRC_STAA8/16-41        AC Q2G0L5.1
#=GS S1QZZ6_9ENTE/6-30       AC S1QZZ6.1
#=GS Q5FIC2_LACAC/16-41      AC Q5FIC2.1
#=GS E8JYM8_9STRE/7-32       AC E8JYM8.1
#=GS D8IHD3_LACFC/16-41      AC D8IHD3.1
#=GS A4VV49_STRSY/7-32       AC A4VV49.1
#=GS C8PC71_9LACO/20-42      AC C8PC71.1
#=GS A0A089XY85_9LACO/3-28   AC A0A089XY85.1
#=GS Q8DRL6_STRR6/4-27       AC Q8DRL6.1
#=GS T0UPH8_9STRE/11-35      AC T0UPH8.1
#=GS S1MV27_9ENTE/11-34      AC S1MV27.1
#=GS G5KIA3_9STRE/14-39      AC G5KIA3.1
#=GS A8AV26_STRGC/5-29       AC A8AV26.1
#=GS A0A089Y0L9_9LACO/19-43  AC A0A089Y0L9.1
#=GS C0MGZ5_STRS7/13-42      AC C0MGZ5.1
D6S364_9LACO/13-38                 ...n-EIQRFSFRKTSIGLASFAISSLIFL......
E8SI63_STAPH/5-29                  ....NQKSIYRIRKYTVGVVSVLATMTFL-......
A0A089ZKL4_9LACO/19-43             ....-KQDHFSIRKLTIGAASVLLGFTFFG......
B9DLE5_STACT/7-31                  ...s--RNRYAIRKYTVGTASALVASVAFL......
Q8E1G3_STRA5/5-26                  ...q--YNKWSIRRLKVGAASVMIAS----g.....
Q8DRK2_STRR6/7-32                  ....QRYTRWSIRRLSVGVASVVVASGFFV......
E8JY21_9STRE/7-31                  ....EKRCRYSIRKLSVGACSLMIGSVLF-......
LIP_STAEQ/4-28                     ....-RQNKYSIRKFSVGASSILIAALLF-m.....
A8AYA5_STRGC/7-32                  ....NRKRVYSIRKFTVGACSVLIGTCAVL......
E8K195_9STRE/6-25                  ...f-KQERFSFRKMKVGLASVAI------......
U2KGC7_9STRE/9-33                  ...e--KQRFSIRKYSFGAASVLIGASLVF......
Q8DRA6_STRR6/9-34                  ....EKKMVYSIRSLKNGTGSVLIGASLVL......
Q8DUW9_STRMU/4-28                  ....EKQKHFSLRKLKFGLVSVAIIAFLF-......
C0MCG2_STRS7/9-33                  ..eq--IRKYAIKKLSVGVASVCVGIGL--a.....
T0TGF4_9STRE/2-26                  ...g-KKERFSLRKYKVGLVSVLIGAVFL-......
Q9A180_STRP1/2-27                  ....EKKQRFSLRKYKSGTFSVLIGSVFLV......
S1N500_9ENTE/12-37                 ....KKKFRFSLRKFSTGVGSVLLGTTLFF......
E8K2T7_9STRE/33-58                 ....ERKQRFGIRKFTVGAASVVIGAVVFG......
E3C5V5_9LACO/17-41                 ...q--RQHYAIKKLTVGVSSVLIGLSFLG......
Q5HS21_STAEQ/5-29                  ....NRIKRFSIRKYAVGVVSIITGATIF-......
Q8E1C4_STRA5/14-39                 ....QTKQRFSIKKFKFGAASVLIGISFLG......
Q5HNF3_STAEQ/4-29                  ...f-RKQKFSIRKFNIGIFSALIATVAFL......
Q74KU3_LACJO/9-34                  ....DTKQRFSIRKLTIGTCSVLLSTLFLG......
E8JXU1_9STRE/7-32                  ....QRYTRWSIRRLSVGVASVVVASGFFV......
E3C7Z7_9LACO/16-41                 ..qh--YTRWSLRKLSIGVASVAIASGFFV......
Q8CVC7_STRMU/10-33                 ...a---QRFSIRKYAFGAASVLIGCVFFL......
T0U0E6_9ENTE/16-41                 ...k-RVLKYSIKKLSVGVASVLVGVGLVL......
E8K2U6_9STRE/7-31                  ....EKSRIFSIRKLTVGVASVAVGLAFF-......
A0A089Y697_9LACO/19-43             ....-KQDHFSIRKLTIGAASVLLGFTFLG......
Q8DYX2_STRA5/9-34                  ....DTKQSYSLRKYKFGLASVILGSFIMV......
A8YUX0_LACH4/17-41                 ....-KKDRFSIRKFTVGAASVLIGFTFMG......
A4VUD0_STRSY/18-43                 ...g-TKQQFSIRKYHFGAASVLLGVSLVL......
V4QYE3_STRIN/2-26                  ....EKKERFSLRKYKSGIVSVLIGTVFF-......
A8AVB1_STRGC/5-29                  ....-REQRFSIRKFSVGAASVLIGITM--ag....
C0MF89_STRS7/5-30                  ....NKKQKFSIRKLSAGAASVLVAASVLG......
B9DJ62_STACT/10-34                 ....-RKNRYSIRKMTAGAASIIVGITLFG......
A4VVP2_STRSY/7-32                  ...q-SKQHYGIRKYKVGVCSALIALSILG......
Q5FJA7_LACAC/16-39                 ....ERQPHFSIRKLTIGAASVLLSTTL--......
G5KEA1_9STRE/13-37                 ...s--KQRFSIKKFKFGAASVLVGLTFLG......
NANA_STRR6/22-47                   ....ERKCRYSIRKLSVGAVSMIVGAVVFG......
E8SH04_STAPH/4-28                  ...n--KNIYSIRKHKLGVASFLLGTLFVV......
F2I4G0_AERUA/16-41                 ....NKFYRYSIKRLSVGVASVAVAAGLLF......
E8SGC5_STAPH/14-39                 ....NRQNRYAIRRFSVGTASILVGATLIF......
T0TJI2_9STRE/6-31                  ..nv--RQRFSIRKSHLGASSVLLGVSI--al....
A8AUR8_STRGC/5-29                  ....-KKQKFSIRKLSLGVCSVLVGIALFG......
Q2FW95_STAA8/4-28                  ...f-RQQKFSIRKFNVGIFSALIATV---tf....
Q5FJC1_LACAC/14-39                 ...k-EKQRFSIRKLTVGTASVLLGTTFLF......
E8K102_9STRE/14-39                 ....ERRCHYSIRKFAIGAASVMIGASIFG......
Q99XV2_STRP1/7-32                  ....NKHSRYSIRKLSVGVTSIAIASLFLG......
U2KNJ2_9STRE/8-32                  ...k-RSQRFSIRKYSLGAASVLLGTAVV-......
T0V7L8_9STRE/6-27                  kdii-----FGIRKSKLGVFSVVIAIM---......
A8AWJ3_STRGC/9-33                  ..hl---RKFSIRKLNVGVCSVLLSTLILL......
A0A089Y066_9LACO/19-42             ....-KQDHFSIRKLSIGAASVLLGF----tyl...
UAFA_STAS1/15-40                   ....NRLNKYSIRKFTNGIASVLIGSTILL......
IGA1_STRR6/7-32                    ....EKQERFSFRKLSVGLVSATISSLFF-m.....
K1LN60_9LACT/2-27                  ....EKNYRYAIRKTTLGVGSVAIAAIL--ag....
E3C831_9LACO/16-41                 ...q-EQQRFGLRKLSIGVASVLLGTSIVV......
B2GBF6_LACF3/16-41                 ....QRYTRWSIRRLSIGVVSVAVASGVFL......
T0V9D9_9STRE/7-32                  ....EKKERFSIRKFSVGVCSALIGLAFLG......
Q74I86_LACJO/5-28                  ...s--QYRYALRKLSVGLTSVAVGLAFM-......
Q99XV0_STRP1/5-30                  ....NTNRHYSLRKLKTGTASVAVALTVLG......
Q74L43_LACJO/11-36                 ...d-SKQRFGIRKLTIGACSVLLSTLILG......
E8SG89_STAPH/3-27                  ...d-QKQLFSIRKFNSGASSVVIASLFF-......
A4VSS5_STRSY/5-30                  ....NKKFRYSIRKFKVGVGSVLIATCLLG......
B9DSF3_STRU0/11-34                 ....--KQRFSLRKYKFGAASVLLGTIF--al....
U2JEM9_9STRE/6-30                  ...k-RSQRFSIRKYSYGAASVLLGTAAF-......
A5VKZ2_LACRD/16-40                 ...q--RQRFGLRKLSVGVASVLLGTTFMV......
V4SHT8_STRIN/14-38                 ..qm--KQRFSIKKFKFGAASVLIGLSFL-......
Q2FXH4_STAA8/5-29                  ....-KKNKYSIRKYKVGIFSTLIGTVLLL......
C0MEV6_STRS7/7-31                  ..dg--KQRFAIKTFKTGAASVLVATLFL-......
E3C8Y6_9LACO/14-37                 ....-RQPRYGLRKLGVGVASVLLSTSF--w.....
Q5FIM7_LACAC/17-40                 ....-RKERFSIRKFSIGAASVLIGFSFM-......
B9DIB2_STACT/18-42                 ...q-SKNRYRIRKFSVGLASVLFGTFLI-......
E8K154_9STRE/7-32                  ....EKRCHFSIRKFAIGAASVMIGASIFG......
Q8CYI8_STRR6/15-38                 ....--QQRYSIRKYYFGAASVLLGTALVL......
E8JXS9_9STRE/19-44                 ...d-RISRFSIRKLNVGVCSVLLGTLVML......
Q74JH9_LACJO/16-39                 ...d-EKQRFSIRKFSVGAASVLIGLSF--......
LIP1_STAA8/2-27                    ...k-SQNKYSIRKFSVGASSILIATLLFL......
CLFA_STAA8/4-27                    ....KKKEKHAIRKKSIGVASVLVGTLI--......
B9EAH6_MACCJ/2-27                  ...f-KNNRYSIRKFSVGTGSVIIGAMLYL......
GH101_STRR6/7-32                   ....EKRCKYSIRKFSLGVASVMIGATFFG......
Q8DYZ1_STRA5/8-32                  ....EKGLKFSIRKFSVGVASVAIGSLLF-......
A8AVB4_STRGC/9-34                  ....EKIQKFSIRKLSVGVGSVAIAALIFG......
E8SES1_STAPH/11-35                 ..tl---SRFSIRKCSVGTASFLIGTVAFF......
T0TXW9_9STRE/9-34                  ....EKMTKYSIRKLSVGVGPVAIGAFLLG......
B9DKE9_STACT/2-27                  ....KKKQLFSLRKLSVGIASVSLGTLVFL......
B0S0B2_FINM2/20-43                 ....-KKPRYALRKLSIGVVSCLIGYAFL-......
Q5FIF3_LACAC/5-29                  ..ev--KNRFSFRKLSTGLATVFLGSIFF-......
A4VXV9_STRSY/9-32                  ....ENKQRFSIKKLSVGVASVSIGFF---i.....
E3C782_9LACO/16-41                 ....QKNQRFTLKKLSVGVASVLIGLTFMG......
Q5FJS0_LACAC/14-38                 ...e--KNRFGFRKLSVGLTTVFLGSIFFL......
G5KE73_9STRE/10-34                 ....-KRQTFSLRKLTVGLCSVYLGSLLIL......
C8PDF1_9LACO/25-48                 ..ip----HFSIRKLTIGAASVLLSTSLYL......
D6S5D7_9LACO/16-41                 ..ng--RQHFSLRKTTLGLASVLLSTTLYL......
E8K103_9STRE/7-32                  ....EKRCKYSIRKFSLGVASVVIGATFFG......
C8PC76_9LACO/18-42                 ..qv---PHFGIRKLAIGTASVLLSTSLYF......
F6CB75_LACKZ/14-39                 ..ng--KPKFGFRKLTVGLAAVTLGTAFFL......
B9DPH4_STACT/9-34                  ...n-LKNKYSIRKFTVGTASILLGSLLFL......
E3C7W1_9LACO/16-41                 ...d-QRQRFTVRKLGIGVVSVLIGAVL--ag....
Q5HKF4_STAEQ/10-35                 ..nl--LNKYGIRKLSAGTASLLIGATLVF......
U2IJA8_9STRE/4-29                  ....EKHHRYSLRKLKFGLASVAVAAFL--tg....
B0S330_FINM2/20-43                 ....NKKLRYGLRKLSIGVVSCFLG-----yai...
B9DIH4_STACT/3-27                  ....KRENKYSIRKFAIGTSSILVASLFF-......
CLFB_STAA8/10-35                   ....NKQNKYSIRRFTVGTTSVIVGATILF......
A8AV25_STRGC/4-28                  ....DRQQRFSFRKYSVGLVSVVVGCLF--y.....
SASG_STAA8/17-42                   ....NKLNKYSIRKFTVGTASILIGSLMY-l.....
G5KDY8_9STRE/15-39                 ....-TKQRFSIKKFKFGAASVLVGLAFLG......
C0MH02_STRS7/11-34                 ....-RKPKFGMRKLSIGLASCMLGMMFL-......
E8JY07_9STRE/90-114                ....EKSCKYSIRKLTVGTASVLLGAVFL-......
E3C756_9LACO/17-40                 ...q--RQRFGLRKLTVGVASVLLGTTFF-......
SPA_STAA8/2-26                     ....KKKNIYSIRKLGVGIASVTLGTLLI-......
A4VXP9_STRSY/7-32                  ....DKRQRFGIRKFTIGACSVLIGATLFG......
A8AXC5_STRGC/9-33                  ..hl---SKFSIRKLNIGVCSVLLSTLILL......
E3C6I4_9LACO/16-41                 ...e-QVPHFGIRKLTVGVSSVLLGLSFMG......
C8PBR2_9LACO/20-45                 ....EKLNKFSIRKLSVGAASVLVGVAL--ag....
E3C835_9LACO/19-41                 ...r---ERFALRKLSVGVVSILVGVAI--y.....
C8PC75_9LACO/16-41                 ....EKVTYYGIRKFSVGVVSVALSSLFLL......
V4Q7I6_STRIN/15-40                 ....EKRQFFSIRRLKVGTASVAIASALFF......
Q1WSI9_LACS1/12-37                 ..ny--KQRWAIRKLTVGVVSVLLGGTML-f.....
PFBA_STRR6/18-41                   ...n---EVFSIRKLKVGTCSVLLAISILG......
F2I4F9_AERUA/16-41                 ....NKFYRYSIRRLSVGVASVAVAAGLLF......
B9DJS1_STACT/16-39                 ...y---NKYSIRKFTVGTASILLGSTLIF......
A8AWS3_STRGC/8-32                  ....ERFQRYSLRKLSVGLVSATIGSFFF-......
ISDB_STAA8/7-32                    ...e-FKSFYSIRKSSLGVASVAISTLLLL......
T1ZFU6_STRIT/11-35                 ....ERYTKWSIRRLSVGVASVVVASGFF-......
D6S3U4_9LACO/17-42                 ....DRQQHFSLRKLSVGLVSVLMGTTVFL......
D6S4F2_9LACO/17-42                 ....EQKPRFGFRKFSVGLASALIATVFYF......
D6S602_9LACO/6-30                  ....NERQRFSLRKLSIGVVSVLLGVTFV-......
Q8DX06_STRA5/2-27                  ....NTKQRFSIRKYKLGAVSVLLGTLFFL......
T1ZFN2_STRIT/2-25                  ....-KKQRFSLRKYKFGLASVVLGTFLV-......
EBH_STAA8/5-30                     ....DKIQKFSIRKYTVGTFSTVIATLVFL......
D6S587_9LACO/12-36                 ..ec---QRFSIRKLSIGAASVLLATVAF-m.....
T0TTB0_9STRE/4-26                  ...h--QPRYGIRKYAVGAASVLIGF----fa....
D6S6B2_9LACO/16-40                 ...k-QRQNWSFRKTTIGLCSVLLSTTLL-......
E8JYZ6_9STRE/4-27                  ...k-EQQRFSLRKYKVGVASVFLGTTL--......
FNBA_STAA8/2-27                    ...k-NNLRYGIRKHKLGAASVFLGTMIVV......
Q5HKK8_STAEQ/3-27                  ....NKKNSYSIRKLSVGASSIIVASMLF-......
F6CDG4_LACKZ/17-40                 ....-KRDRFSIRKFTVGAASVLIGRTFL-......
Q8CZ52_STRR6/7-31                  ....ERRCRYSIRKLSVGACSLMIGAVLF-......
Q5HS13_STAEQ/18-43                 ....NKVNKYSIRKFTVGTASILVGATLMF......
E3C608_9LACO/11-34                 ....-TRQRFALRKLSVGVVSVLIGLTFI-......
A4VY42_STRSY/39-64                 ....EKKQIFGIRKLNVGVASVGIAAALFL......
Q5HKE8_STAEQ/18-43                 ....NKLNKYSIRKFTVGTASILLGSTLIF......
Q74LY6_LACJO/16-40                 ....DKQERFSIRKFSVGAASVLVGTAVL-......
V4QT53_STRIN/4-27                  ....ERKHIFSIRKTVLGVGSVLLGVLL--......
K1LKR4_9LACT/16-36                 ....NRIERYGIRRLSVGVASVAVA-----......
R5QBG6_9FIRM/17-42                 ....EKKPYYGIRKLSVGIVSCMLGHLLFF......
Q5FKA5_LACAC/16-39                 ....ERKPHFAIRKLTIGAASVLLGTSL--......
D6S603_9LACO/6-30                  ..da--KQRFSLRKLSIGVVSVLLGFTFV-......
E3C671_9LACO/10-35                 ..ev--KQRFSLRKLKIGTVSVLLGATFFL......
Q8DZ94_STRA5/9-34                  ....DKQTQYTIRKLSVGVASVATGVCIFL......
Q74HP2_LACJO/17-41                 ...q--KQRFSIRKFTVGAASVLIGLTFMG......
E8JYK9_9STRE/7-32                  ...e-KVIKYSIRKFSIGVGSAVIGAVLFG......
K1MH12_9LACT/16-41                 ....NKVNRYGIRRLSVGVASVAVAGLLF-m.....
Q8DQP4_STRR6/7-32                  ....NRKRVYSIRKFAVGACSVMIGTCAVL......
Q5HKF8_STAEQ/5-30                  ..ne--TRRFSIRKYTVGVVSIITGITIFV......
V4R195_STRIN/10-35                 ....EKRQRFSIRRLSIGVGSVLIGICLFG......
T0TXM2_9STRE/7-32                  ....EKRPVFSIRKLSVGACSVVIGISALG......
SDRD_STAA8/18-43                   ....NRLNKFSIRKYTVGTASILVGTTLIF......
Q5M5L4_STRT2/16-40                 ...e--QQRFSIRKYSFGVASVLLGTSLVF......
C8PD26_9LACO/16-41                 ...e-HINRYSIRKLKVGVASVAIAGCFVL......
Q74HU0_LACJO/3-28                  ....NKKERFSIRKFSIGAASVLIGFTLFG......
A8AVS2_STRGC/2-27                  ....KRQQRFSLRKFKFGLASALLGTALIF......
K1LBH0_9LACT/17-41                 ....NRKPRYGMRKVSFGLASCMLGFMI--y.....
Q5HQ38_STAEQ/14-38                 ....-RKNHYAIRKFTVGTASIIVGSFLFF......
A8AXF9_STRGC/7-32                  ....QKYTRWSIRRLSVGVASVAVASGFFV......
A0A089Y475_9LACO/18-43             ....QKQDRFSIRKLTIGAASVLLGFTFLG......
LIP2_STAA8/5-30                    ..qe--ERKYSIRKYSIGVVSVLAATMFVV......
A4VSQ8_STRSY/9-33                  ....-KEQRFSFRKFSFGLASAVIANVILG......
Q5FIP7_LACAC/16-39                 ...d-EKQRFSIRKLSVGAASVLIGLAF--......
F6CG01_LACKZ/14-39                 ..ng--KQKFALRKLTVGLTTVMLGTTF--al....
K1LN36_9LACT/16-41                 ...n-RIVRYAIKRLTVGVGSVIVATSLL-m.....
F2I830_AERUA/17-41                 ....NKKIRYGIRKLSIGIVSCALGC----wil...
Q74HA8_LACJO/24-48                 ....DRQDRFSIRKFSIGAVSVLIGSFIF-......
Q8DN05_STRR6/7-32                  ....ERKVHYSIRKFSIGVASVAVASLVMG......
A0A088A2X1_APIME/29-53             ....-KQDRFSIRKLTIGTASVLLGFTFLG......
E8K213_9STRE/4-27                  ....ENKQRFSIRKYAIGAASVLIGFAF--......
E8SH87_STAPH/4-28                  ...q-QKQHYGIRKYAIGTSSVLLGMTLF-......
C8PC68_9LACO/27-52                 ....EKITHYSIRKVSFGAASVAIAVAFMF......
D6S4X0_9LACO/18-42                 ...q--VQHFGFRKFSVGLTSVLLSTSLYF......
C8PCN3_9LACO/16-41                 ....EKVTYYGIRKFTVGVVSVAISAAFLL......
T0UTD1_9STRE/2-27                  ....NRQERFSLRKYKFGVASVLLGAVLVF......
ISDH_STAA8/8-31                    .lrs----FYSIRKSTLGVASVIVSTLFL-......
U2JEU0_9STRE/5-29                  ....-KKQKFSIRKLSLGVCSVLVGIALFG......
C0MDN4_STRS7/2-26                  ....EKKERFSLRKYKSGMVSVLIGILFL-......
Q5FKA6_LACAC/16-39                 ....ERKQHHGIRTLSVGAVSVLLGTTL--......
K1LF19_9LACT/16-41                 ....NKVNRYGIRRLSVGVASVAVAGLLF-m.....
E8SG87_STAPH/3-27                  ...d-QKQLFSIRKFKRGVSSVVIASLFF-......
C8PBR3_9LACO/4-27                  ....ERLNKFSIRKLTVGAASVLIGVAF--......
E3C6Y5_9LACO/22-39                 ...k---------KLTLGVASVALGTTFIL......
E8JZ10_9STRE/9-34                  ....EKKMVYSIRSLKNGTGSVLIGASFIL......
T0V184_9STRE/10-31                 ....-KQEKFSIRKLSVGVVSLAIA-----gl....
SDRC_STAA8/16-41                   ....NRLNKFSIRKYSVGTASILVGTTLIF......
S1QZZ6_9ENTE/6-30                  ...e-TRGRFSIRKLSIGVCSVCLGFAI--l.....
Q5FIC2_LACAC/16-41                 ....NQKAHFSIRKLTIGAASVLIGITFMG......
E8JYM8_9STRE/7-32                  ....NRKSIYSIRKFTVGTCSVLIGTC---svl...
D8IHD3_LACFC/16-41                 ....QRYTRWSIRRLSIGVVSVAVASGVFL......
A4VV49_STRSY/7-32                  ....EKRQRFGFRKMSVGLVSAAVTSLFFV......
C8PC71_9LACO/20-42                 ....DKKPRYGMRKLTIGTVSCLLG-----fa....
A0A089XY85_9LACO/3-28              ....DKQDHFSIRKLSIGAASVLLGFTFFG......
Q8DRL6_STRR6/4-27                  ....EKQQRFSIRKYAVGAASVLIGFAF--......
T0UPH8_9STRE/11-35                 ....EKREYFGIRKLKVGVASVAIATTLF-......
S1MV27_9ENTE/11-34                 ....EKKNKYSIRKLSVGVGSVIIG-----fil...
G5KIA3_9STRE/14-39                 ....QTKQRFSIKKFKFGAASVLVGLLFLG......
A8AV26_STRGC/5-29                  ....-RKQRFSIRKYAIGVASVLIGLALVG......
A0A089Y0L9_9LACO/19-43             ....-KQDHFSIRKLTIGAASVLLGFTFFG......
C0MGZ5_STRS7/13-42                 ....EERQLFGIRKLKLGVASVAIATAF--slgtvs
#=GC seq_cons                      .....+pp+aSIRKholGsuSVllGsshh.......
//
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