GenomeNet

Database: Pfam
Entry: bact-PGI_C
LinkDB: bact-PGI_C
Original site: bact-PGI_C 
#=GF ID   bact-PGI_C
#=GF AC   PF10432.6
#=GF DE   Bacterial phospho-glucose isomerase C-terminal SIS domain
#=GF AU   Finn RD, Coggill PC, Bateman A
#=GF SE   Gene3D, pdb_1tzb
#=GF GA   24.50 24.50;
#=GF TC   24.50 24.70;
#=GF NC   24.20 23.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Glucose-6-phosphate_isomerase
#=GF RN   [1]
#=GF RM   15252053
#=GF RT   A novel phosphoglucose isomerase (PGI)/phosphomannose isomerase
#=GF RT   from the crenarchaeon Pyrobaculum aerophilum is a member of the
#=GF RT   PGI superfamily: structural evidence at 1.16-A resolution. 
#=GF RA   Swan MK, Hansen T, Schonheit P, Davies C; 
#=GF RL   J Biol Chem. 2004;279:39838-39845.
#=GF DR   INTERPRO; IPR019490;
#=GF CC   This is the C-terminal SIS domain of a bacterial phospho-glucose
#=GF CC   isomerase EC:5.3.1.9 protein which is similar to eukaryote
#=GF CC   homologues to the extent that the sequence includes the cluster
#=GF CC   of threonines and serines that forms the sugar phosphate-binding
#=GF CC   site in conventional PGI. This domain contributes a good
#=GF CC   proportion of the active catalytic site residues. This PGI uses
#=GF CC   the same catalytic mechanisms for both glucose ring-opening and
#=GF CC   isomerisation for the interconversion of glucose 6-phosphate to
#=GF CC   fructose 6-phosphate [1].  It is associated with family SIS,
#=GF CC   Pfam:PF01380.
#=GF SQ   173
#=GS C8VY07_DESAS/199-339      AC C8VY07.1
#=GS G8R8D5_OWEHD/179-324      AC G8R8D5.1
#=GS C6WJ51_ACTMD/200-347      AC C6WJ51.1
#=GS E4NC15_KITSK/233-385      AC E4NC15.1
#=GS G8SLA5_ACTS5/221-398      AC G8SLA5.1
#=GS D2PMF2_KRIFD/195-348      AC D2PMF2.1
#=GS A0A0A7PC15_9BACT/196-345  AC A0A0A7PC15.1
#=GS W5TNZ8_9NOCA/208-387      AC W5TNZ8.1
#=GS K4R990_9ACTN/225-375      AC K4R990.1
#=GS K7RUT9_PROA4/197-342      AC K7RUT9.1
#=GS E0SR12_IGNAA/176-321      AC E0SR12.1
#=GS B8D166_HALOH/203-355      AC B8D166.1
#=GS A9A1U2_NITMS/177-322      AC A9A1U2.1
#=GS C7M132_ACIFD/185-336      AC C7M132.1
#=GS Q9RTB3_DEIRA/176-321      AC Q9RTB3.1
#=GS M9SI90_9EURY/185-333      AC M9SI90.1
#=GS A0A0B5EW82_9ACTN/225-375  AC A0A0B5EW82.1
#=GS PGMI_AQUAE/167-316        AC O66954.1
#=GS M4YKA6_9EURY/185-333      AC M4YKA6.1
#=GS D9TC09_MICAI/217-394      AC D9TC09.1
#=GS C9YZI8_STRSW/225-375      AC C9YZI8.1
#=GS A8L9R4_FRASN/207-386      AC A8L9R4.1
#=GS D7CUC1_TRURR/152-296      AC D7CUC1.1
#=GS E1QR66_VULDI/185-330      AC E1QR66.1
#=GS D3DJW9_HYDTT/166-315      AC D3DJW9.1
#=GS A2BMR0_HYPBU/176-325      AC A2BMR0.1
#=GS D3Q0A5_STANL/214-390      AC D3Q0A5.1
#=GS D5XCA5_THEPJ/203-354      AC D5XCA5.1
#=GS I6WPE9_PROPF/191-338      AC I6WPE9.1
#=GS H8GYI1_DEIGI/137-282      AC H8GYI1.1
#=GS PGMI_SULAC/165-299        AC Q4JCA7.1
#=GS B3QXK7_CHLT3/198-349      AC B3QXK7.1
#=GS B1I0X3_DESAP/201-351      AC B1I0X3.1
#=GS D9S2I1_THEOJ/198-349      AC D9S2I1.1
#=GS D8K187_DEHLB/201-351      AC D8K187.1
#=GS A0A0D4DT08_9ACTN/228-378  AC A0A0D4DT08.1
#=GS I3TDQ6_THEC1/173-320      AC I3TDQ6.1
#=GS A0A0B5I179_9ARCH/179-326  AC A0A0B5I179.1
#=GS A0A089X6B9_STRGA/225-374  AC A0A089X6B9.1
#=GS I4AFI2_FLELS/181-331      AC I4AFI2.1
#=GS D6Y6B1_THEBD/214-376      AC D6Y6B1.1
#=GS D5TZP7_THEAM/173-321      AC D5TZP7.1
#=GS H6L175_SAPGL/179-326      AC H6L175.1
#=GS F4LWH6_TEPAE/198-349      AC F4LWH6.1
#=GS S0EUW6_CHTCT/208-361      AC S0EUW6.1
#=GS G2NC99_STREK/226-376      AC G2NC99.1
#=GS H1XXY8_9BACT/193-342      AC H1XXY8.1
#=GS A0A0A7LMY0_9BACT/178-328  AC A0A0A7LMY0.1
#=GS PGMI_SULTO/163-297        AC Q96YC2.1
#=GS D1AF46_THECD/209-378      AC D1AF46.1
#=GS I7A3L4_MELRP/193-344      AC I7A3L4.1
#=GS D2BEM1_STRRD/207-366      AC D2BEM1.1
#=GS E8N4S9_ANATU/198-348      AC E8N4S9.1
#=GS I0GZA0_ACTM4/221-398      AC I0GZA0.1
#=GS I4F361_MODMB/210-375      AC I4F361.1
#=GS T0N4E3_9EURY/165-313      AC T0N4E3.1
#=GS F4CTB1_PSEUX/210-367      AC F4CTB1.1
#=GS T0MUV4_9EURY/163-306      AC T0MUV4.1
#=GS C7NFH6_KYTSD/209-385      AC C7NFH6.1
#=GS I0A0H2_FERFK/176-322      AC I0A0H2.1
#=GS H2JQ77_STRHJ/225-375      AC H2JQ77.1
#=GS Q47LY1_THEFY/211-369      AC Q47LY1.1
#=GS E6N8R9_9ARCH/189-333      AC E6N8R9.1
#=GS R9T6G6_9EURY/196-344      AC R9T6G6.1
#=GS Q6A746_PROAC/188-334      AC Q6A746.1
#=GS F4LWN0_TEPAE/202-354      AC F4LWN0.1
#=GS A4YHU4_METS5/137-271      AC A4YHU4.1
#=GS S0E6N8_GIBF5/205-353      AC S0E6N8.1
#=GS B6Z255_9ACTN/225-375      AC B6Z255.1
#=GS C7MXZ7_SACVD/202-351      AC C7MXZ7.1
#=GS A1SGK6_NOCSJ/197-339      AC A1SGK6.1
#=GS H6RKX0_BLASD/210-375      AC H6RKX0.1
#=GS F8JVA8_STREN/233-385      AC F8JVA8.1
#=GS Q5SIM3_THET8/149-290      AC Q5SIM3.1
#=GS Q5SIM3_THET8/149-290      DR PDB; 1WIW A; 149-284;
#=GS Q5SIM3_THET8/149-290      DR PDB; 1WIW B; 149-290;
#=GS G0EE21_PYRF1/185-331      AC G0EE21.1
#=GS Q9KZL8_STRCO/225-375      AC Q9KZL8.1
#=GS F9FUU4_FUSOF/205-353      AC F9FUU4.1
#=GS E3J0X9_FRASU/207-382      AC E3J0X9.1
#=GS H8KMA9_SOLCM/185-322      AC H8KMA9.1
#=GS Q0RR87_FRAAA/207-387      AC Q0RR87.1
#=GS F8AYT7_FRADG/219-390      AC F8AYT7.1
#=GS M1E6Z3_9FIRM/189-341      AC M1E6Z3.1
#=GS A0A059W7Y9_STRA9/228-376  AC A0A059W7Y9.1
#=GS K0KDG9_SACES/200-347      AC K0KDG9.1
#=GS E8U7C8_DEIML/139-287      AC E8U7C8.1
#=GS R4L822_9ACTN/206-382      AC R4L822.1
#=GS PGMI_AERPE/173-325        AC Q9YE01.2
#=GS A0A0A7V9B2_9ARCH/190-335  AC A0A0A7V9B2.1
#=GS L0ACJ9_CALLD/183-331      AC L0ACJ9.1
#=GS F3ZDU6_9ACTN/218-370      AC F3ZDU6.1
#=GS E6S784_INTC7/206-376      AC E6S784.1
#=GS PGMI_PYRAE/166-301        AC Q8ZWV0.1
#=GS PGMI_PYRAE/166-301        DR PDB; 1TZB A; 166-301;
#=GS PGMI_PYRAE/166-301        DR PDB; 1TZB B; 166-301;
#=GS PGMI_PYRAE/166-301        DR PDB; 1TZC B; 166-301;
#=GS PGMI_PYRAE/166-301        DR PDB; 1X9I B; 166-301;
#=GS PGMI_PYRAE/166-301        DR PDB; 1X9H A; 166-301;
#=GS PGMI_PYRAE/166-301        DR PDB; 1X9I A; 166-301;
#=GS PGMI_PYRAE/166-301        DR PDB; 1TZC A; 166-301;
#=GS PGMI_PYRAE/166-301        DR PDB; 1X9H B; 166-301;
#=GS B5YA06_COPPD/170-319      AC B5YA06.1
#=GS R7XZF3_9ACTN/198-340      AC R7XZF3.1
#=GS V4ISW2_9ACTN/233-382      AC V4ISW2.1
#=GS A1RXY2_THEPD/182-333      AC A1RXY2.1
#=GS V6KBN0_STRRC/65-214       AC V6KBN0.1
#=GS F2R534_STRVP/228-377      AC F2R534.1
#=GS U5VRE8_9ACTN/221-398      AC U5VRE8.1
#=GS W5WK79_9PSEU/200-347      AC W5WK79.1
#=GS D7CPH7_SYNLT/191-342      AC D7CPH7.1
#=GS T0MWG7_9EURY/123-268      AC T0MWG7.1
#=GS A6WER3_KINRD/216-384      AC A6WER3.1
#=GS V6JVY4_STRNV/225-376      AC V6JVY4.1
#=GS D2SFK4_GEOOG/210-379      AC D2SFK4.1
#=GS A0RV56_CENSY/219-364      AC A0RV56.1
#=GS G2PAK2_STRVO/283-432      AC G2PAK2.1
#=GS D0MI20_RHOM4/193-344      AC D0MI20.1
#=GS F2IGM8_FLUTR/177-324      AC F2IGM8.1
#=GS F6CN91_DESK7/199-350      AC F6CN91.1
#=GS B4U6U3_HYDS0/167-316      AC B4U6U3.1
#=GS F2NKY7_MARHT/152-295      AC F2NKY7.1
#=GS A0A068NS28_9BACT/195-346  AC A0A068NS28.1
#=GS E4U726_OCEP5/152-295      AC E4U726.1
#=GS D3F930_CONWI/197-346      AC D3F930.1
#=GS M9SF49_9EURY/174-322      AC M9SF49.1
#=GS PGMI_THEAC/163-309        AC Q9HIC2.1
#=GS A4X3I9_SALTO/218-395      AC A4X3I9.1
#=GS D7GCL2_PROFC/192-334      AC D7GCL2.1
#=GS A4FNK2_SACEN/200-348      AC A4FNK2.1
#=GS Q6KZP1_PICTO/158-304      AC Q6KZP1.1
#=GS R8BSV1_TOGMI/205-353      AC R8BSV1.1
#=GS A8MBZ9_CALMQ/175-319      AC A8MBZ9.1
#=GS C1D145_DEIDV/144-285      AC C1D145.2
#=GS N4U086_FUSC1/205-353      AC N4U086.1
#=GS K9ZXW0_DEIPD/139-282      AC K9ZXW0.1
#=GS B8D5F5_DESK1/233-382      AC B8D5F5.1
#=GS F4F6A5_VERMA/218-395      AC F4F6A5.1
#=GS D7BVH5_STRBB/254-403      AC D7BVH5.1
#=GS D3PQ75_MEIRD/151-294      AC D3PQ75.1
#=GS F4A194_MAHA5/202-353      AC F4A194.1
#=GS T0NC12_9EURY/159-306      AC T0NC12.1
#=GS T0NKG9_9EURY/158-304      AC T0NKG9.1
#=GS B1VUW3_STRGG/226-378      AC B1VUW3.1
#=GS A0A0A8EP73_9ACTN/228-376  AC A0A0A8EP73.1
#=GS S5UVX0_STRCU/225-375      AC S5UVX0.1
#=GS A0A075JH74_9MICO/348-415  AC A0A075JH74.1
#=GS A0A0A7KM08_9DEIO/137-281  AC A0A0A7KM08.1
#=GS Q82DD2_STRAW/225-375      AC Q82DD2.1
#=GS Q0B095_SYNWW/187-338      AC Q0B095.1
#=GS A4XIQ5_CALS8/198-349      AC A4XIQ5.1
#=GS A4YIG6_METS5/172-294      AC A4YIG6.1
#=GS PGMI_SULSO/156-288        AC Q97WE5.1
#=GS F5XQR3_MICPN/191-336      AC F5XQR3.1
#=GS A0A085LBQ3_9FIRM/205-356  AC A0A085LBQ3.1
#=GS A0A0A2IWL2_PENEN/213-361  AC A0A0A2IWL2.1
#=GS F4B690_ACIHW/167-301      AC F4B690.1
#=GS B3ET58_AMOA5/177-324      AC B3ET58.1
#=GS V5RX60_9BACT/191-340      AC V5RX60.1
#=GS A0A0A1DPH4_NOCSI/196-341  AC A0A0A1DPH4.1
#=GS E6SGL9_THEM7/230-383      AC E6SGL9.1
#=GS C0Z9T4_BREBN/202-353      AC C0Z9T4.1
#=GS I0AKC9_IGNAJ/192-343      AC I0AKC9.1
#=GS D3SLB9_THEAH/166-315      AC D3SLB9.1
#=GS Q2RKU9_MOOTA/202-353      AC Q2RKU9.1
#=GS Q2JF05_FRASC/207-382      AC Q2JF05.1
#=GS Q1IXY9_DEIGD/140-289      AC Q1IXY9.1
#=GS A0A075JH74_9MICO/209-312  AC A0A075JH74.1
#=GS A0A0C5G197_9ACTN/225-375  AC A0A0C5G197.1
#=GS F0RLG8_DEIPM/140-290      AC F0RLG8.1
#=GS G4RPY4_THETK/169-298      AC G4RPY4.1
#=GS D9Q2S4_ACIS3/137-283      AC D9Q2S4.1
#=GS F3ZZM7_MAHA5/202-354      AC F3ZZM7.1
#=GS D6XBP1_9ACTN/1-134        AC D6XBP1.1
#=GS F2LB72_BURGS/211-360      AC F2LB72.1
#=GS E2Q5E2_STRC2/225-378      AC E2Q5E2.1
#=GS R4PYH9_9BACT/198-347      AC R4PYH9.1
#=GS B8E0A4_DICTD/201-351      AC B8E0A4.1
#=GS A3DNP1_STAMF/173-321      AC A3DNP1.1
#=GS E4TSH6_MARTH/186-335      AC E4TSH6.1
#=GS A0LS31_ACIC1/209-378      AC A0LS31.1
#=GS Q3Z946_DEHM1/202-352      AC Q3Z946.1
#=GS I0I8J7_CALAS/141-285      AC I0I8J7.1
C8VY07_DESAS/199-339                 ..............n-QNPAKQLARLLYN....RIPVFWG......SAGITEVAAYRWKEIINESAKLPAFWNMLPDL..DFSETLAL....................................KSHCDLQRQFFVVFLR.DAY...DH.........PMVQRRTEA......I......KEM.I......AENA...A......GSTDLN.SS.......GS....TT..LARA......FSLFYTGDYAGIYLALLCGSDP-------------gc........................................
G8R8D5_OWEHD/179-324                 ..............i---EAEQLASRLRG....KTAIIYA......-ISGSAGIAARWRQQLNENAKMLAWEAEIPEM..NHNELVGW....................................E---GGSAQYAPVFLR.HDN...DF.........DRNQKRIEI......I......KNI.I......GEKT...N......HINEVW.SK.......GN....GP..IEKT......LYLVHFGDWVSYYLSEFNKVDIMDIKSIDLLKSEL..........................................
#=GR G8R8D5_OWEHD/179-324      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
C6WJ51_ACTMD/200-347                 ...............FVNPAKSLALRVAE....RTPLLWG......LDDMATAVAGHGAGVLARHAGLVCDVAPHR--..--QAITRTalhrravq...................gtsgadifaDPDDEPGGQVRVLLLA.VRR...GQ.........QAEQAKLAA......V......RSL.A......GADV...L......EPAEEV.SG.......GD....AV..CSAL......L--ALRFELASLYLGLAAG----------------t.........................................
E4NC15_KITSK/233-385                 ..............y-DNPAKSLAARLAE....TVPLLWT......EGAPAAAAGERFAAALADRAGLPALAARLPEA..LTAHRGMFtgglggd......................pddffrdRVDEPVPLQLQVLLLRhTPGa.aEL.........EQPGWPVAR......A......RRL.A......TAHE...V......RITEQT.SA.......QE....DP..VQAL......AELIGLTDFAAVYLGLA------------------tr........................................
G8SLA5_ACTS5/221-398                 ...............FVNPAKALALGLAG....SVPIVWG......SSPLATVAARRFADTLAANARYPVMAGALGEA..GRGRVGLLdgvfgglae..................gsrdifadpEDADEAVTRLRLVVLR.DGG...LNpeddadepvAVEERRADA......I......QTL.A......DRRG...V......RCDVLT.AE.......GG....ST..LERL......ASLVAVPDFASLYLALAHGLDPMAVPAISEMKE--l.........................................
D2PMF2_KRIFD/195-348                 ..............a-SNPAKDLSLMLAD....ALPLVWG......GSVLAARAARRVVEALRLASGRPALAADAGHL..LP---VLNqppr...........................dvfadPFDKPEELRPGLVILD.DGV...DD.........PGVAEHRRQ......L......EEK.A......ERHD...V......RVHVVT.QA.......NG....TD..IARY......AALTQHGRYAAAYLGIGLG----------------rygteatetpiv..............................
A0A0A7PC15_9BACT/196-345             ..............k-NNLAKQIAKMTIG....KTLVIFG......-GELTWPLAYKWKISWNESAKNLAFSNQYPEF..NHNEFIGW....................................-SSHPVEKPFTVFDIR.SNL...EQ.........ARIRERMEL......S......DRL.L......SGKR...P......KAHVLE.LQ.......GR....TL..MQQL......LWGLVLADAASIYTAILNGVNPGPVHLIEKLKAEL..........................................
#=GR A0A0A7PC15_9BACT/196-345  pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
W5TNZ8_9NOCA/208-387                 ...............FHNPAKTLAARMRE....RRLVLSG......DSPAAAVVAQHGAEVLLQTAGQIAAAADLTEA..VAANARLVesaavtapgydplfhdeqldgpapvdrarvfvvsadA--DQVAARRRLAVFG.TGAgivDA.........DLVNVDVEL......M......RTE.As...vpRDAG..aG......EPQSPV.AG.......RG....SE..LEQL......AVLILRLEMAAAYLRLL------------------tgpaa.....................................
K4R990_9ACTN/225-375                 ..............y-SNPAKTLAAELAD....ALPVVWT......EGASAGPAGRRFAAALAELAGRPAVVAELPEA..LASHNALLagplaasa....................dpddffrdRVEEAPAMHARVVLLR.DRP...--.........SGGLSAAPA......A......REL.A......LSHD...T......PISELE.PE.......PG....DE..LENL......AELIAITDFAAVYLALASG----------------a.........................................
K7RUT9_PROA4/197-342                 .............al--NPAKDMACALAD....ADPLLWG......GSVLAARASRRFAEALRRASGRSALSAD-AAA..LMPVIMATeprd...........................pfadpD-IDGAAHRPVLVVLD.DGA...--.........PDPLGSRSR......L......EEA.C......RRRD...V......AVRTIG.LPlg...teEE....GP..VGNY......VTLLLQGRFAAAYLALGLG----------------r.........................................
E0SR12_IGNAA/176-321                 ............aqr---DSDKLFEFLKN...sKIPTIVA......-TTRYQALAIRTKNELNENAKMLARVEIAPEL..FHNDIVGW....................................E---GTQIKDKTLIINsDID...--.........-YENELLEF......Y......ENY.L......KENG...V......ETYRLQ.LR.......G-....SL..LERY......LYGSLVVGLTSIKLANIRGIDPLQTKSIAMYKDML..........................................
#=GR E0SR12_IGNAA/176-321      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
B8D166_HALOH/203-355                 ...............EKNPAKQLAVDLDN....YIPLIYG......SLDYYDVVAWRWKNQFGENGKKLAFYNVIPNL..HHDEAVGW....................................EMEKEVLERFYLVVLR.DSE..lDL.........DNIKKRKDV......T......VEI.L......RERI...G......KVIEVY.AE.......GH....TR..LARM......FSLIYLGDFVTIYHAIARGIDPTPVNIIDYFKKKM..........................................
#=GR B8D166_HALOH/203-355      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A9A1U2_NITMS/177-322                 ..............k-KNKSLELAKWINN....-IPIIYY......-PNGFKAAAIRFKNSLQENAKLHAMSEDIIEM..SHNGIVSW....................................----EKTSSIQPILLE.GKD...DY.........IKTKKLQKI......V......KEY.F......KKNH...I......QYNVIS.SP.......TG....SI..LTKL......VYLIYLLDYSSIYKAIIEKIDPSPVKSIEFLKKK-i.........................................
#=GR A9A1U2_NITMS/177-322      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
C7M132_ACIFD/185-336                 ............gtl----ASDLASALVG....TIPIVLG......SGAVGQVAALRWKNQINENAKALAVASVLPEA..GHNELTAF...................................eAYPELLASTVSLVFLR.HDG...EH.........PQISRRVAF......M......ERE.I......APRV...H......RAVSVH.GQ.......GV....GE..LATF......FDLAFVGDVMSLRLAEALGTDPGPIPMLNALKQY-l.........................................
#=GR C7M132_ACIFD/185-336      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
Q9RTB3_DEIRA/176-321                 ..............d-DNPARTLAWSLWG....RAPLLLA......-APDAEALPQAWQQLLARIGKTLAVPLS-GDP..LPVVTGAF....................................EAQHEHGDGRIALLLG.DLD...--.........----PALEL......S......REV.L......ETRI...D......EVVHLP.VP.......GD....TEsaYAGQ......LALWYFGAWVAAYLAERYGLQAGDLSVLAR-----aqavl.....................................
M9SI90_9EURY/185-333                 ............edg---IAWRIAKDLEG....HVPVVYG......-APDMEAIAVRMKNQLNENSKIIAFSGVVPEF..NHNEVVGW....................................-YDDPYRTKFMPVVIC.DDR...-L.........VEISKILKA......T......LDL.L......ESRD...V......PVSVID.TK.......GE....SL..LERM......IYGIMVGDHISLYIAALHGIDPCNVDPIVDIKTRM..........................................
#=GR M9SI90_9EURY/185-333      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A0A0B5EW82_9ACTN/225-375             ..............y-HNPAKTLAAELAD....SLPLIWT......EGLCAGPAGRRFAGALAELAGRPALAAELPEA..LPAHGALLagvlaagg....................dpddffrdRVEEPQAMRARVVLLR.DAL...--.........NGGLSAAPA......A......REL.A......LGHD...T......ALSELE.PG.......EG....GE..LERL......AELIAITDFAAVYLALASE----------------v.........................................
PGMI_AQUAE/167-316                   .............lk--QKGKEIANRIYG....YIPVVYS......-TPLTAHIAERWKGQINENSKSPAYFTILPEM..HHNEVMGW....................................-SNPELRNKFVYLLMF.DEK...DH.........HRVKLRVDI......T......KKI.L......EDFG...V......VPIMLK.GE.......GN....SY..LARS......LYLVHLADWVSVFLAELYGYDPVPVKTIERIKEEL..........................................
#=GR PGMI_AQUAE/167-316        AS    ...............................................................*.................*..............................................................................................................................................................................................*.............................................
M4YKA6_9EURY/185-333                 ..............e-DSYARYVAKRIVG....YVPVVYG......-SPDLSATAVRMKNQLNENSKIVAFSGTMPEF..NHNEVVGW....................................-YEDPLRKNFLPIIIN.DDD...-L.........TDVRKIVKA......T......IST.L......KSRG...L......DPIIVD.VK.......GE....SV..SERI......IYAIMFGDYVSLFLAANRKVDPCNVDPIVDIKTRM..........................................
#=GR M4YKA6_9EURY/185-333      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D9TC09_MICAI/217-394                 ...............FVNPAKSLALGLSG....SIPIVWG......SSPLATVAARRFGDTLSANARYPVVAGALGEA..GRGRVGLLdgvfgglae.................gerdifadpgD-DEPDGTRLRLVLLR.DGG...LNadddtdeplAVEERRADA......V......QTL.A......ERRG...V......RCDVVT.AE.......GG....SA..LERL......ASLVAVPDFASIYLALAHGLDPMAVPAITEMKE--l.........................................
C9YZI8_STRSW/225-375                 .............yg--NPAKTLAAELAD....SLPVIWT......EGQAAGPVGRRFASALADLAGRPALAAQLPEA..LASHAVLLsgplaasa....................dpddffrdRVEDPPAFHARVVLLR.DRP...--.........TGGLSAVPA......A......REL.A......LGHD...T......AISELE.PE.......EG....SD..LETL......AEMIAITDFAAVYLSLASG----------------a.........................................
A8L9R4_FRASN/207-386                 ...............FVNPAKTLALELAG....ALPLWWG......TTRLSEVAAIRAAGVLAANAGYPALVGALPHP..AEDQVALFrgafgsgsggaasdg.....gegtgaddefadffrdRVDDEAVVRLRLILLR.DPA..gEH.........PEVARAAER......A......VML.A......GEHG...V......GVTELR.AE.......GM....AP..LERL......ASLIGLIDFAGSYVGLVLGVDPGA-----------alrlrei...................................
D7CUC1_TRURR/152-296                 ...............EDNPAKALAWALLN....RVPLLLA......-SRADAPALEIWQRLLGRVGKTLAITVG-SHP..LEVLTGAF....................................EARHALADDIVGVVLG.GGD...--.........AETRLACEV......L......ATR.A......A--Q...L......EPFALP.DA.......PT....DP..GART......LALWYAGLWVAAYLALLQGQSPQDTPVY-------araqqa....................................
E1QR66_VULDI/185-330                 ..............r-VDDAINLAKQLVN....SVPVVWV......-TESRRGVGIRFKNDLNENAKYYSVVSVVPEG..AHNDIAAV....................................---TTKQGGLKHVAIM.GPN...--.........DYEGMYEEV......L......IDV.L......SSFG...A......KPIIVK.LE.......GK....TP..LETE......MYGVTYLGMVTLALAELLGVEPVSTEPIDRLKNL-l.........................................
#=GR E1QR66_VULDI/185-330      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D3DJW9_HYDTT/166-315                 ..............i-KEQAYRLAQRLEG....YIPVVYA......-TPLMDAVALRWKTQINENAKTLCYTATLPEL..HHNEVVGL....................................D--NPITRNLCTFVLLfDPE...DH.........PRNLKRLEI......T......EQI.L......KDLG...V......VPALIK.GE.......GN....EF..LNRL......FYLIYLGDWASFYLSQLYGYDPIPVKVIDSIKEKL..........................................
#=GR D3DJW9_HYDTT/166-315      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A2BMR0_HYPBU/176-325                 .............lr--EDAETEAGRLVD....WLGTVAGgwlsivAAEPYYPAAVRFRSELAENAKLASDASQVPEA..GHNIIVGM....................................----AGRRDTALLILD.---...--.........PVEEPWTTI......L......KGF.A......EAVG..pA......SSYTLR.LR.......GK....GM..LPKL......VWATWIAGLSSTLYAERHGLDPEAIPAIKAFRRL-v.........................................
#=GR A2BMR0_HYPBU/176-325      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D3Q0A5_STANL/214-390                 ...............FVNPAKALALDLAG....AIPVVWG......SSPLAGVAARRFGDMLAANARYPVVSGELGEV..GRGRVGLLdgvfgslae.................gerdifadpdDQATDGGTRLRIVLLR.DDG..lENde....dnpPPDTRRADA......V......AEL.A......DRRG...I......RCDTFA.AE.......GG....SA..LERL......ASLIAVPDFASVYLALAHGLDPHSVPAVSEMKD--ft........................................
D5XCA5_THEPJ/203-354                 ...............EQNLAKQLATKFYN....RLPVIWG......VSGTTEVVAQRWKGQINENAKAPAYWAVLPEL..NHNEIVGF....................................EKPENVLKQLEVVILR.DRA...DH.........PRVQKRIEI......S......KTI.I......KDAV...S......GVTEVY.SS.......GN....ST..LART......FSLTYTGDYTSVYLATLYGIDPTPVKMIDFLKQKL..........................................
#=GR D5XCA5_THEPJ/203-354      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
I6WPE9_PROPF/191-338                 ..............g-DNPGKDLAVGLAD....SFPLVWG......GTTLAGRASRRIAETLRRASGRLALAADAEEL..---EAVLLdtprrd........................vftdpfE--QDAEIGPALLLLD.ADQ...VP.........EPMTETARR......L......ARL.A......DCVG...V......RVCHIS.SGma...elGA....SD..VERY......VTLLLQGRYAATYLGIGLG----------------p.........................................
H8GYI1_DEIGI/137-282                 .............eg--NPARDLAWSLWG....RAPLLLA......-APDADALPHAWQSLLARTGKTLAVPVP-GDA..LPFVTGAF....................................EAQHEKGDGRIALILG.EAD...--.........----AALHV......A......REV.L......ESRI...D......EVVQVP.YPa.....gSE....GG..YAGQ......LALWYFGAWVAAYLAERYDQSPADPPMLARA----qavl......................................
PGMI_SULAC/165-299                   ............sev----STRIANRITG....KVPIFYA......-S-DLLPIAERFKQEVNENAKYPAFFSQLPEA..NHNEIELY....................................--SSQQGNQFIPIVIP.SDK...--.........-----IDEA......T......ASL.I......NA--...-......--ELIY.PP.......YK....SI..LKNI......SGMFLIAGLASVKLASQLNIKAEELRIIPKIRER-t.........................................
#=GR PGMI_SULAC/165-299        AS    ...............................................................*.................*..............................................................................................................................................................................................*.............................................
B3QXK7_CHLT3/198-349                 ..............l-DNQAIQLAAKTVG....KLPLIYT......ADDFTSIVGVRWKGQICENAKILAYANVLPEL..NHNELVGW....................................KLNQDLLKQIHVIMLH.DQD...DH.........ARTQFRMEI......T......KKV.I......SDYT...E......SVTEVY.SK.......GH....SL..MARV......FSLIILGDWVSYYLAILNKIDPSPIEVIDHLKQAL..........................................
#=GR B3QXK7_CHLT3/198-349      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
B1I0X3_DESAP/201-351                 ..............r-ENLAKQLALNLQG....RLPVIWG......ASGTTEVVAQRWKGQFNENAKAPAYWNVFPEL..NHNEVVGF....................................EQPEDLLGRIWIIILK.DDA...DH.........PRVRLRMKI......T......REM.V......SKA-...A......GLTEVF.AS.......GP....TE..LARL......YSLIYLGDYASMYVAALAGIDPGPVRVIDYLKNEL..........................................
#=GR B1I0X3_DESAP/201-351      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D9S2I1_THEOJ/198-349                 ..............d-KNPAKALARKIHG....KLPVIYG......SQGVTDALAVRWKGQMNENGKHPAFYNVFPEL..NHNEIMGF....................................EGDPRLLAEMEIVILR.SPE...EN.........DRVKKRIEI......T......SSL.I......RDKV...S......GINEVW.PA.......GD....TR..LERI......MYHVIYGDYVSAYLAVLNEKDPTEIDFINILKERM..........................................
#=GR D9S2I1_THEOJ/198-349      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D8K187_DEHLB/201-351                 ..............s-HNLAKETAYRLYG....RLPVIYG......-AGIATEVAYRWQTQFNENSKQWAFTQILPEL..NHNAIAGY....................................QLPQALVPSLSVMILR.SNH...LS.........PRIVRRMQV......S......AEL.L......MKAG...A......RVGYGD.GR.......GI....SP..LAQM......MSLVLLGDYVSYYLALLNNADPSPVENISYLKQKL..........................................
#=GR D8K187_DEHLB/201-351      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A0A0D4DT08_9ACTN/228-378             ..............y-TNPAKTLAADLAE....ALPLIWT......EGTVAGAIGRHFATVLAGLAGIPALAAELPEA..LTTHRPLLagalaaga....................dpedffrdRVEQPAALHARILLLR.DRR...E-.........AGPLSATRA......A......NEL.A......DECE...T......ALSELQ.PE.......SG....SE..LESA......TELLAITDFAAVYLALA------------------dt........................................
I3TDQ6_THEC1/173-320                 .............ia--SEASSLAEFAYS....RELLVVA......THSPLEPLAVRAKSEFNENSKIVVKVDVAPEW..MHNDIVGY....................................--EKPLFDEYRVVAFY.DPD...-D.........QAGRGLVEF......M......VGE.H......ERRG...R......RVRVLA.LR.......GV....NK..VGKV......LYAAMLFGLASVELALKRGLDPAATESIARYKS--a.........................................
#=GR I3TDQ6_THEC1/173-320      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A0A0B5I179_9ARCH/179-326             ............iek---TGKELAGKYRN....KIPIIYS......-AQEFFCIAEKWKTDINENAKTHAFYNVLPEF..NHNEICAY....................................Q---YNQEIFKPLILS.YDD...YH.........PKIKKRIGI......F......RKL.L......KEYK...V......PVAEVN.FV.......GN....TL..LARL......FSSIWMGLFFAYYLAMEYDRDPTPVEIIEKLKKDL..........................................
#=GR A0A0B5I179_9ARCH/179-326  pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A0A089X6B9_STRGA/225-374             ..............y-SNPAKTLAAELAD....ALPLVWT......EGTSAGPAGRRFAAALAELSGTPAMVAELPEA..LAAHSALLagplaara....................npddffrdRVEEPPALHARVVLLR.DRP...--.........IAGLTAAPA......A......RDL.A......LSHD...T......PISELE.PD.......PG....GE..LETL......AELIAITDFAAVYLALA------------------sr........................................
I4AFI2_FLELS/181-331                 ..............i-KKEAKQLAIALKG....KFPILYA......-DAILEPMLIRFQQQINENAKQLCHVAVFPEM..NHNELVGW....................................HLPKDILSKTHILLFH.SDY...DH.........ERVNRRMEI......C......ENI.F......NKHT...T......AITHIS.AK.......GN....SF..LEQV......FYLIYLTDWVSYYLAEENGVDPFPVEVINYLKSSL..........................................
#=GR I4AFI2_FLELS/181-331      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D6Y6B1_THEBD/214-376                 .............fl--NPGKSFAMELAD....RLPLLWG......CSPLARVAARSLACRLHRCAGYPALVGEILEA..GHEQIGLFngpfgaq.....................pidadpfgE--EGGPPRPRLFLFR.DTE...EH.........PLVAERREA......V......ARL.A......EDRG...V......PVSEIS.AE.......GA....HP..LERL......ASLIGLSDYAGVYLALGYGRDPSRIAALAEL----ga........................................
D5TZP7_THEAM/173-321                 .............av--ADAGVIAEWVNR...cKGLLVIS......THSPLESLGLRGKNEFNENAKIPVKVDVAPEW..MHNDIVGY....................................--EEPFLKDFTVLEVV.DPD...-D.........KVGVMLVDF......M......RTI.Y......AKVT...G......RFHRLV.LE.......GV....SL..LDKI......MYGSMVFGLSSCKLARMRGIDPLKTASILEYKK--v.........................................
#=GR D5TZP7_THEAM/173-321      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
H6L175_SAPGL/179-326                 .............im--EKAKKMAQFMSG....KFPVLYT......-HDRMGSVVLRLRQQLNENAKILCGHHLIPEM..NHNELVGW....................................---RKQEGDFAVLIFR.SKF...EH.........ERNQARIKI......N......KEI.I......NHYT...Q......TLIEIK.LK.......GD....SL..IEEA......MYAVHLGDWISWELSVLRQVDATEVKVIDFLKGEL..........................................
#=GR H6L175_SAPGL/179-326      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
F4LWH6_TEPAE/198-349                 ..............k-DNPAKALAGKLHG....KLPLIYG......TSNLTDIIAVRWKGQMNENAKHPAFYNAFPEL..NHNEIMGF....................................EGDSKLLKTFEIIILR.SPN...ES.........DRIKKRIDI......T......TDI.L......KEEV...S......GITEIW.PE.......GE....SS..LEQM......LYHIMFGDYVSAYLAILNNKDPKEIDFIDELKERM..........................................
#=GR F4LWH6_TEPAE/198-349      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
S0EUW6_CHTCT/208-361                 ..............d-QNPAKQLARALYG....KIPVIYG......SQGYRGVVAYRWKSQFNENTKIAAFSNVLPEQ..NHNEILAW....................................VQAQKQAPNWAVIFLR.DPNerfEN.........PRIVRRVEV......T......TEL.I......R-RV...A......PVYEVL.AE.......GE....SL..LARL......FSLVYIADFVSVYLAYLYGVCPTDISYIDYLKAEL..........................................
#=GR S0EUW6_CHTCT/208-361      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
G2NC99_STREK/226-376                 ..............y-SNPAKTLAAELAD....SLPLVWT......EGEAAGPVGRRFAAVLAELAGRPALVAELPEA..LPAHGGLLagafaaga....................dpddffrdRVDEPETMRARVVLLR.DRP...--.........TGGLTAAPA......A......REL.A......LSHE...T......AISELE.PE.......EG....SE..LEML......AELLAVTDFAAVYLSLAS-----------------ds........................................
H1XXY8_9BACT/193-342                 ............ils-----RSLAYTIEN....KIPVIYS......TAPYLRSVSRSWKDEIEQKAKALAIAGVIPEM..NHNEIVGW....................................EWNSDMIKNFIAIFLE.NKD...VD.........SRILKRIEI......S......KEI.I......KKRG...V......EVVEVY.AD.......GK....SR..LEKV......FSLVLLGDWMSYYLALLYKKDPTEIKNVDYIRQKM..........................................
A0A0A7LMY0_9BACT/178-328             .............vr--EEAQVITGALYE....RLPIVYG......-DALLESTAVRFQQQVNENSKQLCHVNSFPEM..NHNEIVGW....................................EFPTKILTATTVLFLH.SAF...DH.........KRVAQRMEL......C......RPV.F......EAQG...A......KVLDVT.AK.......GK....SL..TAQI......FYLIHLLDWVSIYLAEKNGTDPAPVKVIDKLKNQL..........................................
#=GR A0A0A7LMY0_9BACT/178-328  pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
PGMI_SULTO/163-297                   .........neisgi-------LASQIIG....KIPIIYS......--STFLPIAERFKQEINENAKYPAFYNELPEA..NHNEIELY....................................SY--PSPYTFYPIVIV.SDK...--.........-----LDEE......S......ANL.-......----...I......NAYKIY.PL.......YQ....SI..LKNI......ASLTLLAGLTSVKLAMLLGVKPEQLNIIPKIREK-t.........................................
#=GR PGMI_SULTO/163-297        AS    ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D1AF46_THECD/209-378                 ...............FVNPAKQIALDLAG....ELPMVWG......SSELAATVAYRMCCQLNENAKYPAVFGGLPEA..NHNQVVAFdgffaggta..................gdiddffrdRAEEAERTRLHLVMLR.DAD...EH.........PQVVKRREI......S......AEL.A......RERG...I......AVTEIT.AE.......GV....HP..LERI......ASLIAMSDYVTVYLAIALGVDPTPVSAIQELKAR-i.........................................
#=GR D1AF46_THECD/209-378      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
I7A3L4_MELRP/193-344                 ..............p-ENRALSLAESLLG....YVPLIYS......VSDYTSVVGTRFKGQFNENSKQHAFFAYFPEL..DHNEIMGW....................................EGYNPQEMNIKLINIW.DDE...YH.........PQVKKRLEI......T......SEV.I......RKTG...C......EIIDLK.SE.......EK....NA..KLRL......VDLIFLGDWATYYYAVIRGFDPTTIDNINYLKARL..........................................
#=GR I7A3L4_MELRP/193-344      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D2BEM1_STRRD/207-366                 ..............f-INPGKSLAMEMAE....TVPMIWG......SSPLAAVAAYRWACQLNENGKYPAVWGEIPEV..NHNQVVAFdgpla.........................trdifaD---ESGRSLRLFVLR.DVE...EH.........PQVARRREV......S......VRM.A......EDRG...V......PVTQIA.AE.......GL....HP..LERL......ATLVELGDYASTYLALGYGVDPTPVSAITELKAR-i.........................................
#=GR D2BEM1_STRRD/207-366      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
E8N4S9_ANATU/198-348                 ..............t-HNPAKRMAGQLFG....RWVVVLA......-ADYLAPVARRWKGQINELAKAWAQFEFLPEA..DHNTLAGL....................................ENPSAMLMNMMALFIQ.APG...IN.........SRNQKRIEL......T......REM.F......MTQG...I......NTDMIV.AR.......GE....GK..LAHI......WTSLLFGDYMAYYLAMAYGIDPTPIPILDAFKSEM..........................................
#=GR E8N4S9_ANATU/198-348      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
I0GZA0_ACTM4/221-398                 ...............FVNPAKALALGLAG....SVPIVWG......SSPLATVAARRFGDTLAANARYPVMAGALGEA..GRGRVGLLdgvfgglae..................tnrdifadpDETDESVTRLRLVVLR.DGG...LNpeddadepvAVEERRADA......I......QTL.A......ERRG...V......RCDVLT.AE.......GG....SA..LERL......ASLVAVPDFASLYLALAHGLDPMAVPAISEMKE--l.........................................
I4F361_MODMB/210-375                 ...............FVNPAKTLALELLD....ALPVIAA......EGPLAGAAAGRVADQLATLAGLPASTFRLPDQ..RVAARTVLagplape.....................agqddffrDRTDDTGRRLRLITIR.DADa.aAHdgg..erepRSAGEAMAE......L......LRI.A......ADSN...V......PVSGLA.DH.......GEperyPR..LARL......ARQLAVADFSAVYLALAL-----------------dhe.......................................
T0N4E3_9EURY/165-313                 .............er--SPIWQLAQKIVDs..rKIPYILS......-WEPFTSLSYRFKTQFNENSKLFALNHNLSEQ..NHNELVPQ....................................LMNGGMAEKFIFLVLEgDYS...--.........SRCKVRLDI......M......ENK.F......S---...S......EIIRIK.PK.......GE....TQ..LEKL......FYLLHYIDILTVEVSLRLSFDPEDVKVLENLKAEL..........................................
#=GR T0N4E3_9EURY/165-313      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
F4CTB1_PSEUX/210-367                 ...............FMNPAKALALRLAE....HTPLLWG......VDAVASAVAAHGAAALATHAGVVAHADDAAR-..-AATATGLrralesgaa..................erdvfhdpfDDPAPAALALRLVLLA.TGE...DE.........PGQALLRRT......G......RDWpV......ADVL...H......PVEEIV.RG.......TP....NA.aVLRA......GVLASRLDIAAVYL---------------------glatrtiep.................................
T0MUV4_9EURY/163-306                 ....lisiskrifes-------------G....KVPYFIS......-WNPTSSVAYRCKTQFNENSKMLANAGYLSEI..NHNELVPM....................................-GMNHEMDPFIYIAFK.NSF...-S.........KRNEKRLEI......T......KKL.S......SR--...-......DFTIIE.LK.......GK....SI..FSQI......MYGVYFGDVLSYHVALLRKVEARDVSIIERLKLE-l.........................................
#=GR T0MUV4_9EURY/163-306      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
C7NFH6_KYTSD/209-385                 ...............FVNPAKVAALALAE....TIPIALG......DGPVAGVAARRAASMLSRTSRIPAAAGELPHS..AGEVVACFdgpyatgdgwnattdr....gpaadggrdifadpflD--APARTPLGLWLLG.RDE...--.........--LGSMAGH......V......STL.A......SDAG...V......RVVDCF.AR.......GE....EA..LVDL......AHLVGRVDFTATYLAIGLGLDPSRSPHLADLRD--l.........................................
I0A0H2_FERFK/176-322                 ..............l-ENYAKNIANEAKD....KIVIFIS......-SKPYLSVAIRFKNDFAENSKSISFVEEIPEF..LHNSIEGIn.................................rlL--MFYKDRIKILSIGgKML...--.........-----FNNI......F......YES.F......KEAL..nL......KITEVD.LG.......SD....GV..LNEI......VRGFKLSGLVSLKLASIYDIDPDETSSIDVYKEKL..........................................
#=GR I0A0H2_FERFK/176-322      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
H2JQ77_STRHJ/225-375                 ..............y-SNPAKTLAAELAD....ALPLVWT......EGSSAGPAGRRFAAALAELAGRPALVAELPEA..LAAHSALLagplaasa....................dpedffrdRVEEPPALHARVVLLR.DRP...--.........ISGLTAAPA......A......RDV.A......LSHD...T......AISELE.PE.......EG....GE..LETL......AELIAVTDFAAVYLALASG----------------a.........................................
Q47LY1_THEFY/211-369                 ...............EDNPAKELALAFAD....TLPVLWG......ATPLTALAARWAAVQFAANARYPVLLPSPPEA..AWAQPAVLtgplqa........................srglfdDPADAPGIRMRLLLFR.DDE...AL.........PEEAADLAR......A......EHT.A......ETAE...V......LVSEVA.AQ.......GR....SP..VERL......AGLIALIDYATLYLAVAYAVEPLTHT---------lvvr......................................
E6N8R9_9ARCH/189-333                 .........qqmveq--------ARPMLG....RHVVIVS......-ADNLYSAAYRLKCQLNENAKHPCHVATAPEA..FHNEVEGW....................................----TNLGNYCYVFLR.SGY...EQ.........LMVSDGLDW......M......KEY.L......RSNG...A......AVIEIG.VK.......SS....SP..VSEL......LKFLLIADLLSLGLACLKKVDPIMLHTIPKLR---pil.......................................
#=GR E6N8R9_9ARCH/189-333      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
R9T6G6_9EURY/196-344                 ..............r-DNLAKTIADNLEN....TLPAIYG......-TISVGPAAKRWRTQINENSKMLSMCGILPEF..NHNQIVGW....................................--ISTPSAPATAVFLR.SVV...DN.........IEISKIVDA......T......TSL.F......KDSG...V......ETIIIN.LE.......GE....SR..LECT......MRGIILGDFVSYYLAALRGVDPTPIDPISKLKERM..........................................
#=GR R9T6G6_9EURY/196-344      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
Q6A746_PROAC/188-334                 ..............a-VNEAKDLACALAD....AEPLLWG......GSVLAARASRRLAQWMRRATGRIALSAD-SAA..LRPVIDSAprrd...........................pfadpDL-DGETRRPVLVVMD.DAE...-T.........EHAAARRD-......L......EQL.C......AAHD...V......TVRSVT.LPlg..ideQS....SP..MSRY......VALLLQGSFAAVYVALGL-----------------dr........................................
F4LWN0_TEPAE/202-354                 ...............EDNPAKQIAMELYG....YIPLVYG......SLDYYDSVAWRIKNQFGENSKLMAFYNVIPNL..HHDEAVGW....................................DMPEDLISKFYLILLR.DDE..lDS.........PKIKKRKDI......T......AEM.L......SARM...G......KVRQVY.AE.......GP....NR..LCRM......FSLVYLGDFITLYAPIYRGVDPTPVNIINLFKTKM..........................................
#=GR F4LWN0_TEPAE/202-354      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A4YHU4_METS5/137-271                 .............na--NEARRVAGDLLSairgRIPVFYA......--SIYLGLAKRFKQEINENAKYPAFFGEIPEV..NHNEIEGY....................................----AHGSGLFPVVFS.SGP...--.........-----LDEV......T......ASL.V......NAKV...I......RISG--.--.......--....--..IRDV......SLLIQSAGFLSVMLARELGEDPEKLTRIPE-----grklv.....................................
#=GR A4YHU4_METS5/137-271      pAS   ...............................................................*.................*...................................................................................................................................................................................................*........................................
S0E6N8_GIBF5/205-353                 .............lk---KAQAIAERLKN...sRIALLST......-ADWYVTLLKQTTMFFNEIAMVPTHRNLLHEF..SHTEVAAY....................................--SNPSEKQAIITFLD.SNA...-D.........QYTKDKVKT......L......EGL.FgskdvpQNKN...I......EFINID.LN.......QD....NF..FKKF......FYGHFFTVYVAYYLGIHSNVEGR------------dlisiaa...................................
B6Z255_9ACTN/225-375                 ..............y-DNPAKNLAAELAE....SLPVIWT......EGVSAAPAGRRFAAALAELAGRPGLTAQLPEA..LASHSVLLsgalaaga....................dpddffrdRVEEAQALHARVVLLR.DRP...--.........LGGLSAAPA......A......REL.A......LSHD...T......AISELE.PE.......DG....GE..LETL......AELIAITDFAAVYVALASG----------------a.........................................
C7MXZ7_SACVD/202-351                 ...............FVNPAKSLALRLAE....HTPLLWG......LDNVAVAVAEHAAYALATHAAVVSEVSHYQHA..LTRSALRRavlksfa.....................vdtifadpDESEGDVLPIRLVLLSiITG...--.........QAADHVRRH......A......GEL.L......PSADv.qA......PADEIT.AD.......DA....G-..--RA......AVLALRFELAALYLGLAAG----------------t.........................................
A1SGK6_NOCSJ/197-339                 ..............a-VNPAKMLAIALAD....TNPLVWG......GSVLAARAARRVSESIRRASGRTALAGDAEHL..LP-VLEAArprdv.........................fddpfaD--GPGDLRPMLLVLD.DGA...EE.........PVVREHRGR......L......QAA.A......AARG...I......RVERVT.TE.......AP....TE..VARY......ASLLLSGRYAAEYL---------------------rigl......................................
H6RKX0_BLASD/210-375                 ..............v-VNPAKTLALELLD....ALPVIAA......EGPLAGAAAIRVADQLATLAGLPATGFRLPDQ..RVAACAVLggplapr......................dagdffrDRADDVGRRLRLLTIR.DSDa.gGHdg....ageREPRSAADA......M......QQV.L......RTAAahdI......PVSGLA.EH.......GDpdryAR..LPRL......ARQLAVADFGAVYLALAL-----------------dhe.......................................
F8JVA8_STREN/233-385                 ..............y-RNPAKSLATELTG....TLPLVWH......QGTATAPVARRFTDALTTLAGLPALGAALPEA..VDRHHAVLtadgggtt...................gdlddffrdRVEEPDRLRPRIVLLR.DSG...--.........---TAPVPA......V......QEA.A......AAHA...T......GVSEIE.TP.......PG....AP..VVAL......AELLTLTDFTAVYLALGHH----------------papda.....................................
Q5SIM3_THET8/149-290                 ...............EENPAKFLAYTLLE....RLPLFYS......--PLFRPLEGAVQTLFARVAKSLSLTPP-PSA..LEFFLVGL....................................EARHEQGDPLAAVLLG.PGE...E-.........------AAL......A......KEI.L......ESRV...D......ALAEVP.AT.......GA....NR..LAQV......MALWYRMAWTAYYLALLYGVDPGDHGLLERLRE--vt........................................
#=GR Q5SIM3_THET8/149-290      SS    ...............EEEEE-TT-THHHH....HHHHTT-......--SHHHHHHHTTSS-GGGGTTEEEEEES-SHH..HHHHHHTT....................................CT---S-TTTTHHHHH.-XX...X-.........------XXX......X......XXX.X......XXXX...X......XXXXXX.XX.......XX....XX..XXXX......XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XX........................................
G0EE21_PYRF1/185-331                 ..............i-EDEAVKTAEVLRG....SKLVVVT......AGWELAPVATRAVQELAENSKKVGIPVYTPEA..LHNFIESV....................................D-VLGTIEGARVLALDwKGY...--.........-TARKLYDH......L......VSK.L......SSV-...V......GTVRVS.IE.......QA....GV..LQAL......AWSTLFVGLASIHLARIEGADPQQIPKIKEARK--v.........................................
#=GR G0EE21_PYRF1/185-331      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
Q9KZL8_STRCO/225-375                 ..............y-SNPAKTLASELAE....TLPVVWT......EGTSAGPAGRRFAAALAELAGTPAVVADLPEAlaAHNALLAGrlaagad......................pddffrdRVDEPPALHARVVLLR.DRP...--.........SGGLTAAPN......A......RDL.A......LGHD...T......PISELE.PE.......EG....GE..LETL......AELIAITDFAAVYLALASG----------------a.........................................
F9FUU4_FUSOF/205-353                 .............lk---KAQAIAERLKN...sRIALLST......-ADWYVTLLKQTTMFFNEIAMVPTHRNLLHEF..SHTEVAAY....................................--SNPSEKQAIITFLD.SNA...-D.........QYTKDKVKTleglfgS......KDI.P......QNKN...I......EFINID.LN.......QD....NF..FRKF......FYGHFFTVYVAYYLGIHSDVEG-------------rdlisiaa..................................
E3J0X9_FRASU/207-382                 ...............FVNPAKLLALELAG....TLPIIWG......TSQATSAAASRAATQLAVTAKYPVLHGGLPHP..GIYQIAAFdgvfgaraaaad............agndeldeffrdRVDDEMTTRLRLILLR.DPG..hEH.........PDVTRRAEA......V......VRV.A......AERG...V......GVTELS.AT.......GS....HP..VERM......ASLVGLLDYASVYLAMLIGIDPSLEPAIHDL----drv.......................................
H8KMA9_SOLCM/185-322                 ......kyistiknk--------------....-Y-VIIT......-DSFFEGVATRFAQQIQENAKLEAFVHVLPEA..NHNAIESY....................................----YSKPGTNFIFLN.SRN...-N.........HRTNLRFAF......V......KEL.L......TKFD...V......PMMELL.VK.......DN....S-..LNTL......FHIIYQLDWLSLQVADKADAVSNQIPNINSLKEF-l.........................................
#=GR H8KMA9_SOLCM/185-322      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
Q0RR87_FRAAA/207-387                 ...............FVNPAKTLALELAG....SLPLVWG......TSAVTSVAAEHVAAQLAAIAKYPAIVGALPHP..GHHQVALFdgpfgagltagstagg....tgarddledffrdrisD--EEESIRLRLILLR.DPD..vER.........PEVGRQAES......A......VAV.A......AERG...V......GVTELR.AE.......GA....GP..LERL......ASLIGLFDFTAVYAALALGIDPTQVPTVRDL----gr........................................
F8AYT7_FRADG/219-390                 .............fi--SPAKVLALELAG....SLPLLWG......TTALTAAAASRAAGQLAANAGYPALLGTLPDS..ASLQAGVLdgpfgvrgadg.............gpaedffrdrvdD--GAEPVRLRLVLLR.DQA..aEH.........PTVTRQAEA......A......VTA.A......AERA...V......AVTELS.AQ.......GA....SR..LERL......ASLVGLFDYTSVYLALALGVDPTPVAAARDL----sa........................................
M1E6Z3_9FIRM/189-341                 ..............e-DNVSKRIAYKLAT...kKNVIIWG......VESISKNIAYRFKSQLEENAKQLSYYSYLPEA..SHNQIVPI....................................-SLVDNKEEYIVLIFRiPQL...ES.........VLVSNIIST......V......KTF.L......NSEG...I......EVLEVF.GS.......GK....NH..VLAG......LDLIYSTDFVSYYLALLKGIEPEPIEPISRMK---vil.......................................
#=GR M1E6Z3_9FIRM/189-341      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A0A059W7Y9_STRA9/228-376             ..............y-TNPGKTLAADLAD....ALPLIWT......EGLVAGAVGRHFATELAGLAGRPALAADLPEA..LTTHRALLagalaaga....................dpddffrdRVDQPAALHARIVLFR.EAE...A-.........-GPLSATRA......A......QQL.A......DERD...T......PLSELE.PT.......AG....SE..LERA......AELLAIADFGAVYLALA------------------g.........................................
K0KDG9_SACES/200-347                 ...............FVNPAKSLALRVAD....RTPLLWG......LDDPATAVAGHGAGVLACYAGLVSDVAGYPQA..LTKSVLHRravrgt.......................sgadifaDPDDEQDGLVRVLLLA.V--...--.........-RQGRRAEF......A......RRS.A......METL...P......GADVLE.PAee..vtgGD....--..AVCA......ALLALRFELAALYLGLAAG----------------t.........................................
E8U7C8_DEIML/139-287                 .............dg--NPARELAWSLWG....RTPMLLA......-ASGDAWLTYAWQTLLARIGKTLSIPVE-RDP..LYILTGAF....................................EARHETGDGRVALLLG.HVD...--.........PELALAREV......L......ETR.I......DEVI..hV......PYTGST.DD.......ED....GQ..YAAQ......LAHWYFAAWVAHYLAERHGVSSEDASPLRE-----vlrtl.....................................
R4L822_9ACTN/206-382                 ...............FVNPAKSLALDLAG....SVPIVWG......SSPLATVAARRFADTLAANARYPVMAGALGEA..GRGRVGLLdgpfggla...................estrdifadPGDEESTTRLRLVVLR.DGG...LNpeddadepvAVEERRAEA......V......QVL.A......ERRG...V......RCDVLT.AE.......GG....SA..LERL......ASLTAVPDFASIYLALAHGLDPMAVPAINEMKE--l.........................................
PGMI_AERPE/173-325                   .............lk--GEAERLAGFISR...yRIASLVT......-CGPGIPLAVRLKNELAENAKMPSRLEIYPES..SHNDIVAL....................................E-AAEGLYGAVFIWIE.HEG...--.........SLCPAVLDV......V......EGI.Y......REYG...V......DTISIE.SSa....rgGP....NA.tVAEY......LSRTLVFGLASVRLALMRGFNPEETPPIDKYKRRL..........................................
#=GR PGMI_AERPE/173-325        AS    ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A0A0A7V9B2_9ARCH/190-335             ..............e-DNTSLELAKWIND....-IPLIYY......-PWGLQSAAIRFKNSLQENSKMHVITEDVIEA..CHNGIVAW....................................----EKKSKIKPILIR.GKD...DF.........IKTKERWQV......L......IEF.F......DKEN...I......EFFEIN.SI.......SG....NI..LSKI......VNLIFLFDYCSIYHGVLNNIDPSPVRSIDYIKNKL..........................................
#=GR A0A0A7V9B2_9ARCH/190-335  pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
L0ACJ9_CALLD/183-331                 ..........rgegl------NIANSISD...kDLYIISG......-CGPYELLANRWRQEFSENAKAVVKSEVYPES..AHNDIVVW....................................Q--VDQKYKPAFIMFE.ADK...DN.........SLCSILTNL......L......ENI.Y......KKQG...S......TLIKIK.PR.......GN....NL..FSKL......IQGTLLAGYVSTYLAMRKGINPTDTSITGEYKKAL..........................................
#=GR L0ACJ9_CALLD/183-331      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
F3ZDU6_9ACTN/218-370                 .............ga--NPAKSLAVELDE....SLPLLWT......EGPASDAVARRLVRLLAARAGRAALTAALPEA..LTAHAALLsrpaetdsg.................ddgmddffrdRVEDTSGPRPRVVLLR.TRT...--.........ADGLTAAPA......V......REL.A......HAHR...V......PLTELA.LP.......EG....QD..LDVL......AELLALTEYTAAYLSLA------------------gq........................................
E6S784_INTC7/206-376                 ...............FENRAKTLATDVAE....STAIILG......SGHLGAVAARRAVAMLGRTGRVPVSSGVLPDS..ASQVVACFdgplaggesn...............gaddifadpyiD--GPPRPPLRLVMLRhKSE...AG.........TDLQLLADR......V......VAA.A......EDAG...V......RVSLID.AE.......SD....DP..LLRV......ASHVALTDFAATYLALGQGFDPATSPHVRLLR---gv........................................
PGMI_PYRAE/166-301                   .pnealihklveefq--------------....KRPTIIA......-AESMRGVAYRVKNEFNENAKIEPSVEILPEA..HHNWIEGS....................................E--------RAVVALT.SPH...IP.........KEHQERVKA......T......VEI.V......G---...G......SIYAVE.MH.......PK....GV..----......LSFLRDVGIASVKLAEIRGVNPLATPRIDALKRRL..........................................
#=GR PGMI_PYRAE/166-301        SS    .-HHHHHHHHHHHTT--------------....HHHHHTT......-EETGGGGTHHHH--S-EEEEE-TTS-HHHHH..HHHHHHH-....................................---------HHHXXXX.XXX...XX.........XXXXXXXXX......X......XXX.X......X---...X......XXXXXX.XX.......XX....XX..----......XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..........................................
#=GR PGMI_PYRAE/166-301        AS    ...............................................................*.................*..............................................................................................................................................................................................*.............................................
B5YA06_COPPD/170-319                 ..............m-KDEAQAIAEKLAN....TDAVYVF......SSQRDYVLSMRFAGEISENAKEVAGFLYMTEA..NHNFLQGF....................................--QHGASPKVGIVVYE.DTE...KY.........ERIELQSSF......L......LRK.A......EENG...S......PAVKIG.LK.......GE....TR..LERL......LYGVLVGDFASIYMAEKKGIDAMPVHIITELKTF-l.........................................
#=GR B5YA06_COPPD/170-319      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
R7XZF3_9ACTN/198-340                 ..............a-VNPAKMLAIALAD....ATPVVWG......GSVLAARAARRVAESLRRSSGRSALAGDAEHL..L-PLIEATrqrdv.........................fadpfaD--DGGELRPLLVVLE.DGS...DD.........PVVREQRGR......L......QAA.A......ASRG...V......RVESVA.AE.......GE....TE..VARY......ASLMLQGTYASEYL---------------------rlgl......................................
V4ISW2_9ACTN/233-382                 ..............y-SNPAKTLAAELAE....SLPLVWT......EGPGAGPIGRRFTALLAEVAGHPALTAALPEA..LPAHGALLvsgiadas....................dpddffrdRVDEPEPLRARVVLLR.DRP...--.........PGGLTAAPA......A......REL.A......LAHD...T......ALSELE.PG.......EG....SD..LAAT......AELIATTDFAAVYLALA------------------tt........................................
A1RXY2_THEPD/182-333                 rasesaenvkslvek-------------G....LTPLVYS......-YRPYISAGYRFKTQLNENAKIHAFYADLPEA..NHNEIMGW....................................--SSPLAGKFFAVLIR.GRE...EP.........FYMDARISF......L......REL.F......ETQG...I......PFLEQK.PV.......FD....AP.hTCEL......LQLIYMLDLVSVAVALKMGVDPTPVDTITKLKKV-l.........................................
#=GR A1RXY2_THEPD/182-333      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
V6KBN0_STRRC/65-214                  ..............y-SNPAKTLAAELAD....ALPVVWT......EGPSAGPAGHRFAAAIAELAGRPALVAELPEA..LAAHSALLagplaasa....................dpedffrdRVEEPPALHARVVLLR.DRP...--.........SSGLTAAPA......A......RDL.A......LSHD...T......PISELE.PE.......EG....GE..LETL......AELIAVTDFAAVYLALA------------------sr........................................
F2R534_STRVP/228-377                 ..............y-SNPAKTLAAELAD....TLPLIWT......EGAAAGPAGRRFAAVLAELAGLPALAAELPEA..MPAHGVLLagdyaaga....................dpedffrdRVEEPQALRARVVLLR.DRP...--.........SDGLTAAHA......A......REL.A......LSHE...T......AVSELE.PE.......EG....GD..LETL......AELLAVTDFAAVYLALA------------------tp........................................
U5VRE8_9ACTN/221-398                 ...............FTNPAKSLALGLAG....SIPIVWG......SSPLATVAARRFADTLAANARYPVMAGALGEA..GRGRVGLLdgpfgglae..................ssrdifadpDEEEEANTRLRLVVFR.DGG...LNpedeadepvAVEERRADA......V......QTL.A......ERRG...V......RCDVVT.AE.......GG....SA..LERL......ASLVAVPDFASIYLALAHGLDPMAVPAINEMKE--l.........................................
W5WK79_9PSEU/200-347                 ...............FMNPAKSLALRLAD....RQPLLWG......LDDTSTAVARHAAFALASHAGQVCDVAGYPLA..LSRPALHRaavrsc.......................sggdlfaDPDEDQAAQARVMLLAvATG...--.........PAAEAARRA......A......EDT.L......PGAD...V......LVPTEE.IS.......GG....EA..VCAA......-VIALRFELAALYLGLAAG----------------t.........................................
D7CPH7_SYNLT/191-342                 ..............d-SNRARFIAGQLYQ....RIPVIWG......CSSTSEVAAMRWKGQINENAKAPAYFNVFPEL..NHNEIVGF....................................EVPEDLVKKLAVIILR.DPD...DH.........GRITKRIEI......T......KDI.L......QGKV...S......SVAEVE.AR.......GN....SF..LAKT......YSLIYVGDYASVYLAELYGINPTPVQVIDYLKARM..........................................
#=GR D7CPH7_SYNLT/191-342      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
T0MWG7_9EURY/123-268                 ...........twqe-------FADEIFSs..nKIPVIFG......-TPKLEGVAYRWKTQFNENAKVLAYSASFPEL..NHNDTMAL....................................-ENTYRKEEFYFFVLT.HKQ...IE.........REIADRIRI......T......SKL.C......K---...I......KMANVE.GD.......GN....TI..FSNI......FTLIHKGDYISYFLAKKRDVDPRNVSIIEDLKREL..........................................
#=GR T0MWG7_9EURY/123-268      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A6WER3_KINRD/216-384                 ...............FVNPAKVIALEVSG....AVPVVLG......DGDLMAAGARRAAGMLARTARVPAVSGALPDD..ASEVVATFggpfastv...................edvfadpflD--GPPGPRLQLLVVR.DSPl.aVS.........DEDRRLADA......V......VTT.A......TDAG...V......RVSEVV.AD.......EG....SP..AQRL......AQVIARVDFAAAYLALASGIDPARSPQVADLKDRL..........................................
V6JVY4_STRNV/225-376                 ..............y-SNPAKTLAAELAD....DLPLIWT......EGTVAAPAGRRFAAVLAELSGRPALAAELPGA..LPAHGLLLggdfagga...................adpddffrdRVEEPQALRSRVVLLR.DRP...--.........VGGLTAAPA......A......REL.A......ISHD...T......AISELE.PQ.......EG....SE..LEAL......AELVAVTDFTAVYLALASG----------------n.........................................
D2SFK4_GEOOG/210-379                 ...............FVNPAKTLALELLD....ALPVIAA......EGPLAGTAATRIADQLATLAGLPVTTFRMPDQ..RVAACAVLrgplape.....................ggeddffrDRAEDTGRRLRLLTVR.DADa.gEHdg....ageREPRSAREA......L......SEA.L......RSAAvanV......PVSALA.EH.......GDperyGR..LPRL......ARQLAVADFTAVYLALALD----------------aersa.....................................
A0RV56_CENSY/219-364                 ...............EDNPALELARWIKG....-MPVIYY......-PWGLQAAAVRFKNSLQENAKCHVIAEDVIEA..CHNGIVSW....................................----EGGGNAQPILIE.GAD...DY.........YKTKERWAI......L......RGF.F......ESRG...I......GYREVR.SV.......KG....GV..LSKI......INLVYLLDYASIYLAVLRGVEPSPVPAIDYIKRHL..........................................
#=GR A0RV56_CENSY/219-364      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
G2PAK2_STRVO/283-432                 ..............y-TNPAKTLAAELAG....ALPLLWT......EGPVAAATGRRFARLLASLAGRPALVAELPGA..LAAHGAMLtgafagga....................dpddffrdRVEEAEALRARIVLLH.EEP...--.........VGPVSAVPT......A......REL.A......LAHD...T......AFSELE.PA.......EG....TP..LERA......AELLAITDFAAVYLALA------------------sa........................................
D0MI20_RHOM4/193-344                 .............sg--NDALELAEALQD....RLPFIYS......GTGLMEAVNLRWRCQIQENAKRLASGNVYPEL..NHNEIMGW....................................EYPGPLHEMIGVIVLR.DRE...DH.........PRVQQRMEV......T......REL.I......SDRA...G......YWAEVQ.SQ.......GE....SR..LARM......MSLVNLGDWVSLYLAVLLGVDPTPVPLIGQLKETL..........................................
#=GR D0MI20_RHOM4/193-344      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
F2IGM8_FLUTR/177-324                 ..............i-KSEAMRLAKELQK....RTIAVYA......-GSEYEAITIRAKQQLNENSKELCWQHVIPEM..NHNELVGW....................................---GGGDNRYACLFIQ.TGD...LT.........MRNQIRFDI......S......VER.T......KSKT...D......KVETIQ.AK.......GS....TP..VEKS......IYLIHLIDWISLYLSDLKHGDPIEIDIIDYLKEEL..........................................
#=GR F2IGM8_FLUTR/177-324      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
F6CN91_DESK7/199-350                 ..............d-SNQAKMLAASFHN....RIPVIWG......SSGTTEVVAQRWKGQINENAKAPACWNVFPEL..NHNELVGF....................................EFPGELLRRLYVVILR.DPQ...DH.........PRVQKRFAI......T......REI.M......EGAV...A......GVVEIM.AR.......GS....DA..LARM......YSLVYIGDYASVYLAMLYGVDPGPVRVIDTLKARL..........................................
#=GR F6CN91_DESK7/199-350      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
B4U6U3_HYDS0/167-316                 ............yee---ISKDIAKSLFG....YVPIIYG......-TPLMEAAAYRFKTQINENSKTPAYNAYIPEM..HHNEVVGY....................................-TNPDINQYLRFVIVA.DKK...EH.........PRVSLRVNM......T......IDI.L......KDKG...F......NPILIS.EE.......GN....SY..ISRL......LKNIYIGDFASYHLANMYGYDPLPVDIITYVKKRL..........................................
#=GR B4U6U3_HYDS0/167-316      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
F2NKY7_MARHT/152-295                 ...............EQNPAKLTAWNLVE....RTPVWVV......-SDRYPELARAAQQVFARVAKSLSISPP-PAG..LEFFITAL....................................EARHEQGDPLVAVVLG.DDE...--.........-----RTRL......A......VEI.L......GTRV...D......TIVELP.PP.......QA....EG.lIAET......MAYWYRLAWVSYYLALMYGQDPGDQEVLSRLRD--at........................................
A0A068NS28_9BACT/195-346             ..............k-DNDAKALAGKMHG....ALPIIYG......LGSWQGYIANRWRCQINENAKHLAFVNTYPEL..NHNEIMGW...................................vGATGQSVGRYVGVVLE.DGS...ES.........VRMKARARV......T......EGL.I......GET-...C......SFTHVP.AL.......GE....TL..LEKM......LTLAHYGDYVSVYLARLNGVDPEDIGSINRLKDEL..........................................
#=GR A0A068NS28_9BACT/195-346  pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
E4U726_OCEP5/152-295                 ...............EDNPAKFFAWNLIE....RIPVWVV......-SERYRGLAAALQQTFARIAGSLSIAPP-PGS..LEFFITAL....................................EARHEQGDPLAAVVVG.EDE...--.........-----RTRL......A......VEI.L......ETRV...D......TVLELP.EP......pAE....GL..IPEM......MAAWYFVAWASYYLAILYGRNPADAEVLARLREE-a.........................................
D3F930_CONWI/197-346                 ............eds---LPKEIARGLHG....TIPQIAG......-AGLTSPVAYRWKTQFNENAKTPAFAAELPEL..NHNEIVGW....................................-QGAAELGRFSAVFLD.DSD...LH.........PRVRQRIEL......T......RGF.I......SPTA...A......SSFRVE.GR.......GE....TR..MERL......VSLVLLGDLVSLYAAVLRGIDPTPVEMLDRLKTV-l.........................................
#=GR D3F930_CONWI/197-346      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
M9SF49_9EURY/174-322                 ............edg---IAWRIAKDLEG....HVPVVYG......-APDMEAIAVRMKNQLNENSKIIAFSGVVPEF..NHNEVVGW....................................-YDDPYRTKFMPVVIC.DDR...-L.........VEISKILKA......T......LDL.L......ESRD...V......PVSVID.TK.......GE....SL..LERM......IYGIMVGDHISLYIAALHGIDPCNVDPITDIKSR-i.........................................
#=GR M9SF49_9EURY/174-322      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
PGMI_THEAC/163-309                   ...........nntv----QENIATEIYAg..rRIPVIYG......-STPYRSVAYRWKTQFNENAKILAYSNYFSEL..NHNDTMPL....................................-RDTYRKDEFYFMAFD.STD...--.........ERIRKRIEV......T......QKI.T......G---...T......SFKKIE.AR.......GS....SL..IARI......FYLIHFGDYVTYHLARIRNVDPQDVSAIEDLKKR-i.........................................
#=GR PGMI_THEAC/163-309        AS    ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A4X3I9_SALTO/218-395                 ...............FVNPAKSLALGLAG....SIPIVWG......SSPLATVAARRFGDTLSANARYPVVSGALGEA..GRGRVGLLdgvfgglve..................gerdifadpDLTAAVGTRLRLVLLR.DGG...LNpeddadeplVVEERRADA......V......QTL.A......ERRG...V......RADVVT.AE.......GG....SA..LERL......ASLIAVPDFASIYLALAHGLDPMAVPAITEMKE--l.........................................
D7GCL2_PROFC/192-334                 ..............s-DNPAKDLAVALAD....AQPLVWG......GSVLAARAGRRVAEALRRASGRAALASG-SEE..LLLVIEGAppr.............................dpfaDPGAGPALRPVLIILD.DQA...NS.........PEMDVERQR......L......VAA.A......RAHD...V......RVVTLD.AG.......RG....SD..LDCY......VSLLQQGRYGAAYLSIGLG----------------r.........................................
A4FNK2_SACEN/200-348                 ..............l-TNPAKSLAMRLAD....RAPLLWG......LDQVSTAVAEHGAYALGCHAGTACDVSSYQQA..VARQALHRaaqglgs.....................eadlfadpE--DNPGGLMRVFLVS.ARF...DA.........ESEATERAA......V......RDL.P......AA--...D......LVTPGE.SV.......RD....DA..VLRS......ALLAARFDLAAVYLGLAAG----------------tl........................................
Q6KZP1_PICTO/158-304                 ............nhd---DIRKEAYKIYEn..sYMPVIYG......-SAPYSWVAYRWKTQFNENSKILAYSNYFPEL..NHNDTMAL....................................-KNTYRKERFVFYVLG.SSR...--.........PRIKQRINI......T......KEI.T......D---...T......EFNIID.ID.......SD....NY..LEKL......FYLIHYGDYISYELAMIRNIDPMDVSTIEELKKRL..........................................
#=GR Q6KZP1_PICTO/158-304      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
R8BSV1_TOGMI/205-353                 .............lk---RAEAIAEKLRG...sRIALLST......-ADWYVTLLKQTTMFFNEIAMVPTHRNLLHEF..SHTEVAAY....................................---SDPATKQAIVTFC.DSN...AD.........DYTRNKIQT......L......EGL.FgskkvpQNRN...I......EFVNID.LD.......QD....NF..FKKF......FFGHFFTVYIAYYLGQYSDVEG-------------rdlisiaa..................................
A8MBZ9_CALMQ/175-319                 ..........selpg------RLASFLKG....YVPMIFA......-PIGLQAVAYRFKNDLNENSKTPAVVAIVPEA..DHNDIVAV....................................----MLKHPVKYIIIRgRTD...--.........DVHDYLMRA......V......EEV.V......KNYS...S......DVEVVE.LK.......GS....SR..LSQE......VYGSMLLGLVSVKLAELYGIDPVRTDPINTLKEK-i.........................................
#=GR A8MBZ9_CALMQ/175-319      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
C1D145_DEIDV/144-285                 ...............EDNPARDLAWSLWG....RMPLLLA......-APDADALPHAWQALLARMGKTLAVP-VVGDP..LPVVSSAF....................................EAQHEKGDAKVAVLLG.DPD...--.........----PALHL......T......REI.L......ESRI...D......EVIHVP.YP.......GG....EAsgYAAQ......LTLWYFGAWVAAYLAERYSTDAAD-----------pavlgla...................................
N4U086_FUSC1/205-353                 .............lk---KAQAIAERLKN...sRIALLST......-ADWYVTLLKQTTMFFNEIAMVPTHRNLLHEF..SHTEVAAY....................................--SNPSEKQAIITFLD.SNA...-D.........QYTKDKVKTleglfgS......KDI.P......QNKN...I......EFINID.LN.......QD....NF..FRKF......FYGHFFTVYVAYYLGIHSDVEG-------------rdlisiaa..................................
K9ZXW0_DEIPD/139-282                 .............eg--NPARELAWSLWN....RTPLLLA......-PQGEGFLTWAWQVLLARIGKSLSLPVE-HDP..LYVLTGAF....................................EARHEHGDGRVALLLG.EED...--.........----QELGL......A......REV.L......ESRV...D......EVIAVPyPE.......GS....GG..YAGS......LALWYFGAWVGYYLAERYGQKPEDSKPLRE-----vlas......................................
B8D5F5_DESK1/233-382                 ..............a-VEEAYRLAEWIHGi..qGLLVIAT......-HTPLEALALRGKNEFNENSKIPVKIDVAPEW..MHNDIVGY....................................--EEPSGIPLKIIEVF.DPA...-D.........EAGCRLVEF......M......DEI.Y......KEVN...A......WRHRLS.LR.......GE....TL..LDKL......IYGSLVLGVASVRLAVLRGIDPLETRSIKRYKES-v.........................................
#=GR B8D5F5_DESK1/233-382      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
F4F6A5_VERMA/218-395                 ...............FVNPAKSLALGLAG....SIPIVWG......SSPLASVAARRFGDTLSANARYPVVTGALGEA..GRGRVGLLdgvfgglae..................gerdifadpEESTPDGTRLRLVLLR.DGG...LNaeddadeplAVEERRADA......V......QTL.A......ERRG...V......RCDVVT.AE.......GG....SA..LERL......ASLVAVPDFASIYLALAHGLDPMAVPAITEMKE--l.........................................
D7BVH5_STRBB/254-403                 ..............y-TNPAKALAAELAG....SLPLLWT......EGPVAAAAGRRFASLLALLAGRPALVAELPGA..LAAHGTLLagslagga....................dpddffrdRVEEAEALRARVVLLY.DEQ...--.........VSALSAVPT......A......REL.A......LAHD...T......ALSELE.PG.......GG....GV..LENA......AELLAITDFTAVYLALA------------------st........................................
D3PQ75_MEIRD/151-294                 ..............s-KNPAKFMAYSLLE....RTPMWVV......-PDRYPGLGQALQQTFSRIGKSLSFTPP-PSA..LEFFVTAL....................................EARHEQGDPIAAVLIG.DDE...--.........-----RRSY......A......QEI.L......ESRV...D......TLIELP.EP......eAE....GT..LAKA......LCYWYRVAWASYYLALLYGVEPGDWEVLDNLRQ--at........................................
F4A194_MAHA5/202-353                 ..............a-DNLSKQLARKFYN....NLPVIYG......VVGTSEVVAQRWKGQICENAKAPAHYNIFPEW..NHNELVGT....................................EVPIDLLKRFQVIMLR.DKN...DH.........PRIQKRIDI......T......KEI.L......KQVE...G......GVTEIW.SR.......GN....GD..IARI......FSLIYIGDYASVYLALLNGVDPSTVEKIDLLKNKL..........................................
#=GR F4A194_MAHA5/202-353      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
T0NC12_9EURY/159-306                 .............dn--SDMESLAREIWSg..kLIPVILG......-FSPFKWVAYRWKTQFNENSKILAFSNYFPEL..NHNETMPY....................................-RGTYRKDEFKFIVIG.HPE...-N.........MRIEERIKW......T......SSL.T......S---...T......PFHRVD.VR.......GK....YL..LDTL......FGLIHKGDYLTYHLAKLLNVDPTDVSLIEELKKKL..........................................
#=GR T0NC12_9EURY/159-306      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
T0NKG9_9EURY/158-304                 ............nha---EMKSEAFKIYEn..sSIPIIYG......-SKPFKSVAYRWKTQFNENAKTFAFYSYFPEL..NHNDTMPL....................................-KSAYRRNEYMFYAFE.SDN...--.........TRINHRISI......T......QEV.T......GER-...-......-FTVIQ.SP.......SN....DY..FTKL......FYLIHYADYVTYELALVRNVDPTDVSTIEELKQKL..........................................
#=GR T0NKG9_9EURY/158-304      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
B1VUW3_STRGG/226-378                 ..............y-SNPAKTLAAELAD....SLPLLWT......EGDAAGPVGRRFAAVLSELAGRPALAAELPEA..LPSHGTLLagdfaaga....................dpddffrdRVDEGETLRARVVLLR.DRP...--.........TGGLSAYPA......A......REL.A......LGHD...T......PVSELE.PE.......EG....SA..LEAV......AELLAITDFTAVYLSLA------------------sapqp.....................................
A0A0A8EP73_9ACTN/228-376             ..............y-TNPGKTLAADLAD....ALPLIWT......EGPIAGAVGRHFATELAGLAGRPGLAAELPEA..LTTHRPLLagalaaga....................dpddffrdRVEQPAALHARIILLR.EAE...A-.........-GPLSATRA......A......QQL.A......DERD...T......PLSELH.PG.......AG....SD..LERA......AELLAIADFGAVYLALA------------------g.........................................
S5UVX0_STRCU/225-375                 ..............y-SNPAKTLAAELAD....SLPVVWT......EGTSAGPAGRRFAAALAELAGRPAVVAELPEA..LAAHSALLagplaasa....................dpddffrdRVEEPPALHARVVLLR.DRP...--.........IGGLTAAPG......A......RDL.A......LSHD...T......PISELE.PE.......EG....GD..LETL......AELIAVTDFAAVYLALASG----------------a.........................................
A0A075JH74_9MICO/348-415             ........lagvasg--------------....-------......--------------------------------..--------....................................----------------.---...--.........---------......I......QES.A......RAAG...A......VVVEMH.PD.......AG....PA..IARA......AQLMHRVDFTATYLALGQGLDPAVSRHVTELRDRL..........................................
A0A0A7KM08_9DEIO/137-281             ..............e-NNPARDLAWSLWG....RTPLLLA......-APDADALPHAWQQLLARTGKTLAV-PLLGDP..LPLASGAF....................................DARHEQGDAKVALILG.DTD...--.........----PALLL......A......REI.L......ESRI...D......EIIHVP.AP......dGA....QG..YPAA......LALWYFGAWVAAYLAERYDTEPADPAVLAR-----aqasl.....................................
Q82DD2_STRAW/225-375                 ..............y-NNPAKTLAADLAD....ALPVIWT......EGPTAGPAGRRFTAALAELAGRPALTAELPEA..LAAHSVLLsgalaaga....................dpddffrdRVEEAQALHARVVLLR.DRP...--.........TGGLSAAPA......A......REL.A......LSHD...T......AISELE.PE.......EG....GE..LETL......AEMIAITDFAAVYLALASG----------------a.........................................
Q0B095_SYNWW/187-338                 ...............EKNPAKKIARELKD....SIPIIWG......SSGISEVAALRWKAQINENAKSPAYYHVFPEL..NHNEIVGF....................................EVPAELVSRLFVVILK.DRF...DH.........ERVKRRMAI......S......RDI.I......KQRV...K......GFVEVE.SR.......GE....SF..LARL......YSLCYTGDYASFYLALENGINPTPVALIDYLKAEL..........................................
#=GR Q0B095_SYNWW/187-338      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A4XIQ5_CALS8/198-349                 ...............EKNLAKRLTLKLWN....KLPIIYG......ISGTTEVIAERWKGQICENSKSPAYFNVFSEL..NHNEIVGT....................................ESPKHILGLFEIVMLH.DIE...DH.........KRNAIRMDI......T......KDL.V......KGIV...S......GVNDIY.SI.......GN....SR..LARM......FSLIYLGDYVSLYLATLYQNDPTPVKKIDILKNKL..........................................
#=GR A4XIQ5_CALS8/198-349      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A4YIG6_METS5/172-294                 .............al--NLAKRLVAKIRG....RIPVFYG......--SLYFPVAIRFKQDLNETAKYPAFYGPIPES..NHNDLEAY....................................----VRAQSLQPFVIG.DQD...--.........------IDY......V......T--.-......-LSV...I......KAEQII.PA.......GS....TP..LKNV......AYLVLLSGLTSLLLAEEEGL---------------teee......................................
PGMI_SULSO/156-288                   .............ik--ADATRLAELLIN....RIPVIYS......--SKYLAIAKRFKQEINENAKHPAFYGEIPEI..NHNEIESY....................................----VHGPSLVSVIVE.SSE...--.........-----IDKI......T......EDV.L......N---...-......-SIVIK.PY.......FN....SD..EKNI......SSLLALAGVTSLEMAKKLNEKPDKLYNIPK-----arql......................................
#=GR PGMI_SULSO/156-288        AS    ...............................................................*.................*...................................................................................................................................................................................................*........................................
F5XQR3_MICPN/191-336                 ..............a-ENPAKDLAMGLAE....AHPLVWG......GSVLAARASRRVAEALRAASGRAALAADADEL..----ITVLesaapr.......................dpfadpfEDAVSADRRPVLLILD.DGN...PE.........PPIRHAHAR......L......RTA.A......ERND...I......RVCVVQ.HA.......SG....SD..VERY......ATVLQTGMYAAVYLAVGLG----------------r.........................................
A0A085LBQ3_9FIRM/205-356             ..............a-KNYAKQLASLLHN....RLPVIWG......SSGTTEVAAQRWKGQINENAKALAYWNVFPEL..NHNEIVGF....................................EGPVELLRRLYLIILS.HPH...DH.........PQVQKRISI......T......KEL.M......SRVV...A......GVSEIN.AS.......GN....AE..LARL......FSLIYLGDYTSVYLAFLYGVDPGPVKVIDQLKKAL..........................................
#=GR A0A085LBQ3_9FIRM/205-356  pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A0A0A2IWL2_PENEN/213-361             .............lk---RAEAIAEKLRG....SRIVLLS......TADWYVTLLKQTTMFFNEIAMVPTHRNLLHEF..SHTEVAAY....................................---SDPANKQAIVTFC.DSN...AD.........EYTRNKIQT......L......EGL.F......GSKE...VpqncniEFVQID.LD.......QE....NF..FKKF......FFTHFFTIYVAYYLGKYSDVE--------------grdlisiaa.................................
#=GR A0A0A2IWL2_PENEN/213-361  pAS   ...............................................................*.................*...................................................................................................................................................................................................*........................................
F4B690_ACIHW/167-301                 ............ykd---LGKELSTKIIG....KIPVFYA......--STYFPIAIRFKQEINENAKSPAFYGEIPEV..NHNEVESY....................................V---RGKDLLLPIVIG.NES...--.........-----IDDV......T......AGV.L......NAE-...-......---RII.PP.......SS....SK..LKNI......SSLVLLAGLTSIYLADTLKENPEKLSIIPRCRER-t.........................................
#=GR F4B690_ACIHW/167-301      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
B3ET58_AMOA5/177-324                 ..............i-QTEAEQVAKKIKG....YLPVIYT......-TTPYESVAIRFRQQLNENSKQLCWHHIFPEI..NHNEIVGW....................................E---TNYQNLAVIMFN.SYT...ED.........ERLELQQKI......A......QDI.I......KKHT...N......NFTILC.AQ.......GQ....TE..LIRS......LYLIHLSDWISFYLAQTTGVDPVEVKSIDQIKSAL..........................................
#=GR B3ET58_AMOA5/177-324      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
V5RX60_9BACT/191-340                 .............ag--NQAKQLAVQLAG....KTPIMYA......-GPKLFPAANKWKICFNENAKNTSWANYYPEF..NHNEFIGW....................................-SSHPVEKPFAVVEIR.SNL...EH.........ERTQKRFEV......T......ERL.L......SGMR...P......SPIVVT.PK.......GD....TV..LQQL......AWSFALGDFVSIYLGILNGVNPTPVELVEKLKVEL..........................................
#=GR V5RX60_9BACT/191-340      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A0A0A1DPH4_NOCSI/196-341             .............si--NPAKVLAISLAD....ANPLLWG......GSVLAARAARRIAESIRRTSGRAALAGDAEHL..L-PVIEAArprnv.........................fadpfaD--ETGDRRPVLVLLD.DGV...DD.........PVVRDQRRR......L......EDA.A......RGHD...V......RIEHVA.SE.......AV....GE..VGRY......ASLLLSGTYAAEYL---------------------rlglvad...................................
E6SGL9_THEM7/230-383                 ..............e--GPAQTLAQRMLD....RPLFLYG......AGRLGQAAAYRWQCQLNENAKLLAHAHAFPEL..DHNEVMGWeg................................apQPRDGDQRRPLSILLQ.APA...DH.........PRNRARMEI......T......AEL.V......GDR-...A......EWVTVT.AQ.......GQ....GR..LAQL......LSLSYLGDFVSVYAALLRGLDPSSIASIQRLKERL..........................................
#=GR E6SGL9_THEM7/230-383      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
C0Z9T4_BREBN/202-353                 ...............EKNAAKQIAIEMDG....LIPVVYG......TLPFFDAPAWRWKNQLGENSKLMAFWNAIPSL..HHDEAVGW....................................DSPSALLKGVHFTLIR.DQE...DS.........EKTTQRVEI......S......ADI.L......RERA...G......GVRVVH.SH.......GV....SR..MARL......FSIVYLADFVSLYAALIRGVDPTPVEVINLFKQKM..........................................
#=GR C0Z9T4_BREBN/202-353      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
I0AKC9_IGNAJ/192-343                 ..............e-NNTALTITQQLLG....FIPVIYS......ASDCTNSVGYRFKSQINENSKLHAFHHEFPEM..NHNEIIGW....................................ESHQQKKLHTKVIYIL.DET...YH.........PQIKRRFQI......V......SEL.I......SKAD...V......EIVSLQ.SN.......EK....NF..KVRI......MDLIFLVDWISFYLGVLRGFDPSEIEYINLLKERL..........................................
#=GR I0AKC9_IGNAJ/192-343      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D3SLB9_THEAH/166-315                 ..............i-KEKAKELAQRLKN....YLPVVYA......-TPLTGVCAVRYKAQINENAKTLCHTALLPEL..HHNEIVGL....................................D-NYLTRQMCHFLLLY.DRE...DH.........PRILRRVQI......T......RDI.L......QEMG...L......VPIELE.GE.......GE....SF..EERL......AYLIYLGDWLSYHLAVLYGFDPLPVKSIDRIKGM-l.........................................
#=GR D3SLB9_THEAH/166-315      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
Q2RKU9_MOOTA/202-353                 ..............k-DNLAKSMAYEMAG....YVPVVYG......SLPLTIAVASRWKNQFAENSKLLAMYNALPAL..HHDEVAGW....................................DAPQSYLRHFYFTFLQ.DAE...DR.........LETTRRIEI......S......QEL.L......ASRA...A......GVRKVA.SV.......GK....SR..LARL......FSLVYLGDFISLYLALIRGVDPTPVEIIDNIKYL-l.........................................
#=GR Q2RKU9_MOOTA/202-353      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
Q2JF05_FRASC/207-382                 ...............FVNPAKTLALELAG....TLPLIWG......TSPVTNVVAERAVTQLATSAKYPAIAGALPHP..ARHQVALFdgafgaglaaag...........dparddlddffrdRAEEDESIRLRLVLLR.DPD..vER.........PDVARQAEA......A......VAV.A......AERG...V......GVTELR.AD.......GG....GP..LERL......ASLIGLFDYTAVYLALALGVDPVQVPAAHDLRR--..........................................
Q1IXY9_DEIGD/140-289                 .............eg--NPARELAWTLWG....RTPLLLA......-AEGAEALPHAWQALLARVGKTLAV-PLLGDP..LALVTGAF....................................EAQHEKGDAKVALLLG.DTD...--.........PALSIVREV......L......ETR.I......DEVL...H......VPYPAS.AG.......AE....QPagYAAQ......LALWYLGAWVAAYLAERYGVDPSDPPMLARA----qavl......................................
A0A075JH74_9MICO/209-312             ...............FVNPAKLAALQLAG....TVPVALA......DGPVAALAARRASSMFARTARVPMTWGELPDD..AADLVATL....................................D---------------.---...--.........---------......-......---.-......----...-......------.--.......--....--..----......-----------------------------------gpftagagegavsapddifadpfldaprqpslgfltlhsdat
A0A0C5G197_9ACTN/225-375             .............ya--NPAKTLAAELAD....ALPVVWT......EGTSAGPAGRRFAAALAELSGVPAVVAELPEA..LAAHGALLagplaaga....................dpddffrdRVEEPPALHARVVLLR.DRP...--.........IGSLTAAPA......A......RDV.A......LDHD...T......PISELE.PE.......EG....GE..LETL......AELIAMTDFAAVYLALAS-----------------ka........................................
F0RLG8_DEIPM/140-290                 .............eg--NPARELAWRLHG....RTPLLLA......-DEGSEGLVLAWQNLLARTGKSYSV-PVLGDP..LPVLSGMF....................................EAQHEQGDAKVGLILG.DLS...--.........----PRLDV......G......REI.M......ESRV...D......EVIHLP.FPepsaesgAD....SD..YAPG......LALWYLGAWTALYLAEIAGQSPEDSPVLHRAQAE-l.........................................
G4RPY4_THETK/169-298                 .......erlksvis--------------....RRPTIVA......-PASMQGVAYRVKNEINENAKMDSPVEILPEA..HHNWIEGA....................................------SSPLMALTSE.--Q...IP.........LEHRRRVEI......T......VDL.V......G---...G......ELFKVD.MT.......IG....GV..----......LTFLKHVGLATAKLALERGIDPLKTPRIDLIKQRL..........................................
#=GR G4RPY4_THETK/169-298      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D9Q2S4_ACIS3/137-283                 .............rg---EGETIARALAG...kDIYIVAG......-CGLFDIVAHRWRQEFSENAKAITKTEFYPES..AHNDMVVW....................................QL--LHNVRKGFVLIEgDGR...--.........-VCAVLEDL......L......RQI.Y......NDQR...D......TVVRVT.PR.......GN....GV..LAQL......LQGSLLGGYTSTYLAMFNGVDPRDTSITGRYKEAL..........................................
#=GR D9Q2S4_ACIS3/137-283      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
F3ZZM7_MAHA5/202-354                 ..............e-NNLAKQIAQELYG....YIPLIYG......SLDNLDAVAWRWKNQFGENSKLMAFWNVIPNL..HHDEAVGW....................................DMPQELIKMFYLIMLRdDVL...DS.........EKIKKRKDI......T......VQI.L......SERM...G......KVRQVY.AT.......GK....SR..LARL......FSLVYLGDFVTLYTPIYRGVDPTPVEVINLFKRKM..........................................
#=GR F3ZZM7_MAHA5/202-354      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
D6XBP1_9ACTN/1-134                   ...............--------------....---MIWT......EGTSAGPAGRRFAAALAELSGRPSVVSELPEA..LAAHSTLLsgplaaga....................dpddffrdRVEEPPALHARVVLLR.DRP...--.........IGGLSAAPA......A......RDL.A......LSHD...T......PISELE.PE.......SG....GE..IETL......AELIAVTDFAAVYLALASG----------------a.........................................
F2LB72_BURGS/211-360                 ..............y-VDKAKKIAEKLAG...sRIAFLAT......-AKWYVQLLKQTTMFFNEIAMVPSHRNLLHEF..SHTEVAAY....................................--SNPSEKQAIVVFLD.NED...-D.........EYTKAKVDT......LhrlfgdKSI.V......QNRN...I......EIVQID.ID.......QD....GF..FKKF......YATHFFMVHVAYFLGVQSDV---------------egrdlisiaa................................
E2Q5E2_STRC2/225-378                 ..............y-SNPAKTLAAELAD....SLPLIWT......EGPGAAPAGRRFAAVLAELAGRPALAAELPEA..LPAHGVLLvsdlaaga....................dpddffrdRVEEPQALRARVVLLR.DRP...--.........IDGLTAAPA......A......REL.A......LGHD...T......PISELE.PE.......GG....TE..LESI......AELLAVTDFAAVYLALAT-----------------patps.....................................
R4PYH9_9BACT/198-347                 ..............q-HNYAKQLALLAVG....KTLVFYA......-PETFGFVAHAWKNAWNKTAKNIAFWNTFPEA..AYGELLGW....................................-TSHPIEKPFAIFDLR.SSL...ES.........TRATRGFDA......T......DKL.L......SGRR...P......KSTSVY.LP.......GE....TL..MEQV......VAGYVLAQFVSIYVAILNNANPSDDTLIERYQKE-t.........................................
B8E0A4_DICTD/201-351                 ...............EQNVAKKVAKMMFK....HIPVIYA......VEEKWKVAAYRWKCQINENSKYPAFYHFFPEL..NHNEIMAW....................................EAIDNVIKPLTLIFLY.TSL...-E.........GEMKIRVEF......M......QEK.I......SARG...V......PVFLWQ.AE.......GN....NP..LTQF......FSLTYLGDFATVYLAYLADKDPFSIGYINELKLR-i.........................................
#=GR B8E0A4_DICTD/201-351      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A3DNP1_STAMF/173-321                 .............av--DKAYELSSFIDEh..kGLPILAT......-HTPFEALVVRGKNEFNENSKIPVKVEVAPEW..MHNDIVGW....................................--EKPFENKYSAIIIR.DPS...-D.........DVGSKLVDF......M......KKI.Y......INNN...I......PIYELE.LH.......GK....TF..LEKL......LYGSLVLGLASVKLARIRGVDPLVTENITLYKK--d.........................................
#=GR A3DNP1_STAMF/173-321      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
E4TSH6_MARTH/186-335                 ............iqi---EAKTLAKNIHS....FYALLYA......-DQKFYPAVLRFQQQLAENSKQLSHTHVFPEL..NHNEIVGW....................................RFPEDHISRSKAILLR.SDF...DH.........PQNQKRMEA......S......KSI.I......LQH-...A......EIIELK.AK.......GK....SF..TQQL......YYFIHLVDWISFYLAEENQVDPFPVENIDYLKNKL..........................................
#=GR E4TSH6_MARTH/186-335      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
A0LS31_ACIC1/209-378                 ...............FVNPAKQLALEIAG....SIPVIWG......AGQLCRTAAKRFARQLHANAKYPALDGGLQEA..AHGSVALFdgpfatsap..................sdifcdpldSGSGPPFPRLRVVLLR.DAM...ES.........PPDAALRAA......A......ETL.A......TDRG...I......RLSEIL.AD.......AG....QP..LERL......AQFIALGDFASIYLALGLGVDPGATPAVLEMKDR-v.........................................
Q3Z946_DEHM1/202-352                 ..............s-NNPAKQLADKLEG....RAVMAFG......-SGVTFPAARRFKTQLNENAKCFAFAEEIPEM..NHNSVVGY....................................QLPQNSGRYWAAVMFK.TTF...LS.........KRIHQRMKI......T......TDI.L......HQAK...I......PVFSID.GY.......GF....SP..LCQA......LSLILQGDFVSLYLAFLNGVDPYPIDAVDYFKQEL..........................................
#=GR Q3Z946_DEHM1/202-352      pAS   ...............................................................*.................*..............................................................................................................................................................................................*.............................................
I0I8J7_CALAS/141-285                 ..............a-TNPAKRLAHRFYA....RVPLLWA......EDGWQAEIAQDWRLRILRYAESAAIVADLSEM..QQAWSMAR....................................-FPNFWGNALCVARIG.EVA...--.........AHHHGQVNM......L......QSI.L......QKRR...F......NTIHIE.VP.......GE....DP..FLRG......IHLLYLGEWVALYLAALYGVDPEA-----------rvplqll...................................
#=GC SS_cons                         .-HHHHHHHHHHHTTEEEEE-TT-THHHH....HHHHCTT......-ECCHHHHCHCCCS-CGCCCCEECCCECHCHH..HHHHHHCT....................................CT---S-TTCCHHHHH.XXX...XX.........XXXXXXXXX......X......XXX.X......X---...X......XXXXXX.XX.......XX....XX..----......XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..........................................
#=GC seq_cons                        .................NsAKpLAhpLts....plPllau.......ushtsssAtRapsplsEsA+hsAhss.lPEh..t+sclsuh....................................c..ps.ttphtlllLc.cst...............thtpthch......s......pcl.h......ppps...s......tlsplp.sp.......us....u...lpch......hpLlhlsDasulYLAlhhGh-P..h..lt.h..............................................
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