GenomeNet

Database: Pfam
Entry: zf-Apc11
LinkDB: zf-Apc11
Original site: zf-Apc11 
#=GF ID   zf-Apc11
#=GF AC   PF12861.2
#=GF DE   Anaphase-promoting complex subunit 11 RING-H2 finger
#=GF AU   Coggill P
#=GF SE   manual
#=GF GA   21.40 21.40;
#=GF TC   21.40 21.40;
#=GF NC   21.30 21.30;
#=GF BM   hmmbuild --amino HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16896351
#=GF RT   The anaphase promoting complex/cyclosome: a machine designed to
#=GF RT   destroy.
#=GF RA   Peters JM;
#=GF RL   Nat Rev Mol Cell Biol. 2006;7:644-656.
#=GF RN   [2]
#=GF RM   10230407
#=GF RT   ROC1, a homolog of APC11, represents a family of cullin partners
#=GF RT   with an associated ubiquitin ligase activity.
#=GF RA   Ohta T, Michel JJ, Schottelius AJ, Xiong Y;
#=GF RL   Mol Cell. 1999;3:535-541.
#=GF RN   [3]
#=GF RM   10888670
#=GF RT   The APC11 RING-H2 finger mediates E2-dependent ubiquitination.
#=GF RA   Leverson JD, Joazeiro CA, Page AM, Huang H, Hieter P, Hunter T;
#=GF RL   Mol Biol Cell. 2000;11:2315-2325.
#=GF DR   INTERPRO; IPR024991;
#=GF CC   Apc11 is one of the subunits of the anaphase-promoting complex
#=GF CC   or cyclosome [1]. The APC subunits are cullin family proteins
#=GF CC   with ubiquitin ligase activity [2]. Polyubiquitination marks
#=GF CC   proteins for degradation by the 26S proteasome and is carried
#=GF CC   out by a cascade of enzymes that includes ubiquitin-activating
#=GF CC   enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and
#=GF CC   ubiquitin ligases (E3s). Apc11 acts as an E3 enzyme and is
#=GF CC   responsible for recruiting E2s to the APC and for mediating the
#=GF CC   subsequent transfer of ubiquitin to APC substrates in vivo. In
#=GF CC   Saccharomyces cerevisiae this RING-H2 finger protein defines the
#=GF CC   minimal ubiquitin ligase activity of the APC, and the integrity
#=GF CC   of the RING-H2 finger is essential for budding yeast cell
#=GF CC   viability [3].
#=GF SQ   247
#=GS D8QKD1_SCHCM/1-89       AC D8QKD1.1
#=GS H2R0U8_PANTR/1-56       AC H2R0U8.1
#=GS G9A002_TORDC/1-100      AC G9A002.1
#=GS H2SCN0_TAKRU/1-80       AC H2SCN0.1
#=GS C4R449_PICPG/68-110     AC C4R449.1
#=GS F2TTM8_AJEDA/41-77      AC F2TTM8.1
#=GS H0GSH6_9SACH/1-102      AC H0GSH6.1
#=GS B0W4Y5_CULQU/1-83       AC B0W4Y5.1
#=GS E1ZKB0_CHLVA/3-85       AC E1ZKB0.1
#=GS F2QWU6_PICP7/1-85       AC F2QWU6.1
#=GS G1QDU7_MYOLU/1-84       AC G1QDU7.1
#=GS G1XU49_ARTOA/1-85       AC G1XU49.1
#=GS Q5KP48_CRYNJ/1-108      AC Q5KP48.1
#=GS F2RRP6_TRIT1/168-244    AC F2RRP6.1
#=GS E0S6X5_ENCIT/977-1056   AC E0S6X5.1
#=GS A4HNB7_LEIBR/1-82       AC A4HNB7.1
#=GS D7L4P2_ARALL/1-57       AC D7L4P2.1
#=GS A2ABX9_MOUSE/1-84       AC A2ABX9.1
#=GS G9PAE6_HYPAI/1-85       AC G9PAE6.1
#=GS B8NW41_ASPFN/1-85       AC B8NW41.1
#=GS G3JK82_CORMM/1-85       AC G3JK82.1
#=GS B0YBV4_ASPFC/1-85       AC B0YBV4.1
#=GS C6F8T8_9CONI/1-38       AC C6F8T8.1
#=GS G1QDW7_MYOLU/1-84       AC G1QDW7.1
#=GS B9WN57_CANDC/1-93       AC B9WN57.1
#=GS A8Q810_MALGO/3-79       AC A8Q810.1
#=GS G2YXM7_BOTF4/1-56       AC G2YXM7.1
#=GS C9ZYL4_TRYB9/1-82       AC C9ZYL4.1
#=GS A2E161_TRIVA/9-93       AC A2E161.1
#=GS E3TG79_ICTPU/1-84       AC E3TG79.1
#=GS O11289_MCV1/1-69        AC O11289.1
#=GS Q2MGS9_CARAU/1-84       AC Q2MGS9.1
#=GS C7GW68_YEAS2/1-102      AC C7GW68.1
#=GS APC11_MOUSE/1-84        AC Q9CPX9.1
#=GS G4T8X7_PIRID/411-503    AC G4T8X7.1
#=GS G1MGG2_AILME/1-84       AC G1MGG2.1
#=GS E4ZSV5_LEPMJ/1-85       AC E4ZSV5.1
#=GS F0Y8G1_AURAN/1-82       AC F0Y8G1.1
#=GS I1QA31_ORYGL/1-84       AC I1QA31.1
#=GS E9DC61_COCPS/1-85       AC E9DC61.1
#=GS B4Q778_DROSI/1-84       AC B4Q778.1
#=GS A7UWL2_NEUCR/1-58       AC A7UWL2.1
#=GS H0YZ96_TAEGU/1-84       AC H0YZ96.1
#=GS F6S976_MACMU/1-55       AC F6S976.1
#=GS E4V3D8_ARTGP/1-85       AC E4V3D8.1
#=GS G8XZV6_PICSO/1-97       AC G8XZV6.1
#=GS H6BMG6_EXODN/1-85       AC H6BMG6.1
#=GS A2Q2S8_MEDTR/1-95       AC A2Q2S8.1
#=GS G3RDJ0_GORGO/1-55       AC G3RDJ0.1
#=GS A6REA3_AJECN/1-83       AC A6REA3.1
#=GS F2EDT1_HORVD/1-84       AC F2EDT1.1
#=GS Q5RJJ5_XENTR/1-84       AC Q5RJJ5.1
#=GS Q3E931_ARATH/1-60       AC Q3E931.1
#=GS H2L8A5_ORYLA/1-84       AC H2L8A5.1
#=GS C1N1J9_MICPC/1-82       AC C1N1J9.1
#=GS C0SJ70_PARBP/1-84       AC C0SJ70.1
#=GS B3LGR7_YEAS1/1-102      AC B3LGR7.1
#=GS F4RQ70_MELLP/1-111      AC F4RQ70.1
#=GS G4LX01_SCHMA/19-102     AC G4LX01.1
#=GS F8MU04_NEUT8/1-85       AC F8MU04.1
#=GS G4UVS1_NEUT9/1-85       AC G4UVS1.1
#=GS H9KJV7_APIME/1-84       AC H9KJV7.1
#=GS E1FIY3_LOALO/276-360    AC E1FIY3.1
#=GS G3XUQ8_ASPNA/1-85       AC G3XUQ8.1
#=GS B6HNC6_PENCW/1-85       AC B6HNC6.1
#=GS G3MH79_9ACAR/23-106     AC G3MH79.1
#=GS E7LSG4_YEASV/1-102      AC E7LSG4.1
#=GS G4YWI2_PHYSP/9-93       AC G4YWI2.1
#=GS APC11_BOVIN/1-84        AC Q3ZCF6.1
#=GS B4HYP4_DROSE/1-84       AC B4HYP4.1
#=GS Q2F5T6_BOMMO/1-83       AC Q2F5T6.1
#=GS F2SB11_TRIT1/1-85       AC F2SB11.1
#=GS Q0V1Q5_PHANO/24-111     AC Q0V1Q5.1
#=GS C5FNV9_ARTOC/221-306    AC C5FNV9.1
#=GS F8QC29_SERL3/1-91       AC F8QC29.1
#=GS B0DXK7_LACBS/1-96       AC B0DXK7.1
#=GS E5S7W9_TRISP/898-981    AC E5S7W9.1
#=GS C8VHR1_EMENI/1-85       AC C8VHR1.1
#=GS F9X0Y9_MYCGM/1-82       AC F9X0Y9.1
#=GS F0VAN6_NEOCL/36-123     AC F0VAN6.1
#=GS B4NXG1_DROYA/1-84       AC B4NXG1.1
#=GS Q5CSH7_CRYPI/23-107     AC Q5CSH7.1
#=GS I1F3X2_AMPQE/5-88       AC I1F3X2.1
#=GS E7NGM0_YEASO/1-102      AC E7NGM0.1
#=GS G0W4R8_NAUDC/1-114      AC G0W4R8.1
#=GS G1RH68_NOMLE/1-55       AC G1RH68.1
#=GS D5GCN7_TUBMM/1-85       AC D5GCN7.1
#=GS I1H6B0_BRADI/1-84       AC I1H6B0.1
#=GS G2QHX1_THIHA/1-85       AC G2QHX1.1
#=GS H2WXZ7_CAEJA/68-154     AC H2WXZ7.1
#=GS D3ZXH8_RAT/1-84         AC D3ZXH8.1
#=GS G8BWX0_TETPH/1-117      AC G8BWX0.1
#=GS C6F8S8_PSEMZ/1-38       AC C6F8S8.1
#=GS B4N7R6_DROWI/1-84       AC B4N7R6.1
#=GS C4R449_PICPG/1-68       AC C4R449.1
#=GS D7FXF9_ECTSI/9-95       AC D7FXF9.1
#=GS D7MN37_ARALL/1-87       AC D7MN37.1
#=GS G0QUS7_ICHMG/15-70      AC G0QUS7.1
#=GS G5BJ80_HETGA/1-84       AC G5BJ80.1
#=GS F1L9Q2_ASCSU/321-405    AC F1L9Q2.1
#=GS B9RFR6_RICCO/46-127     AC B9RFR6.1
#=GS G0RK25_HYPJQ/1-84       AC G0RK25.1
#=GS G9N248_HYPVG/1-85       AC G9N248.1
#=GS G2X8A6_VERDV/69-99      AC G2X8A6.1
#=GS Q5B7W6_EMENI/1-68       AC Q5B7W6.1
#=GS D6CH21_VITVI/2-81       AC D6CH21.1
#=GS E2C0X9_HARSA/1-84       AC E2C0X9.1
#=GS E9B6X9_LEIMU/1-82       AC E9B6X9.1
#=GS G2YXM6_BOTF4/1-57       AC G2YXM6.1
#=GS E3RS67_PYRTT/1-85       AC E3RS67.1
#=GS F4X344_ACREC/1-84       AC F4X344.1
#=GS G1N0C0_MELGA/273-358    AC G1N0C0.1
#=GS C5FG19_ARTOC/1-85       AC C5FG19.1
#=GS C8Z4R1_YEAS8/1-102      AC C8Z4R1.1
#=GS C4Y237_CLAL4/1-89       AC C4Y237.1
#=GS Q5ACJ8_CANAL/1-91       AC Q5ACJ8.1
#=GS C1GMS4_PARBD/26-89      AC C1GMS4.1
#=GS G7JEI7_MEDTR/1-83       AC G7JEI7.1
#=GS H3EGH4_PRIPA/91-174     AC H3EGH4.1
#=GS A6XQA2_BOTFB/26-66      AC A6XQA2.1
#=GS B3N7C8_DROER/1-84       AC B3N7C8.1
#=GS D8QKD3_SCHCM/1-58       AC D8QKD3.1
#=GS G4NGM3_MAGO7/1-85       AC G4NGM3.1
#=GS F6I4I3_VITVI/54-137     AC F6I4I3.1
#=GS G1TPK6_RABIT/1-84       AC G1TPK6.1
#=GS E3MCW7_CAERE/54-140     AC E3MCW7.1
#=GS G7E7B3_MIXOS/1-125      AC G7E7B3.1
#=GS B9HHF0_POPTR/3-48       AC B9HHF0.1
#=GS G5E2C7_9PIPI/1-78       AC G5E2C7.1
#=GS H0GDW4_9SACH/1-102      AC H0GDW4.1
#=GS H0EIN7_GLAL7/33-85      AC H0EIN7.1
#=GS I1IEM6_BRADI/1-84       AC I1IEM6.1
#=GS G3U1E4_LOXAF/1-84       AC G3U1E4.1
#=GS B4ITK2_DROYA/67-141     AC B4ITK2.1
#=GS H3J5A0_STRPU/17-96      AC H3J5A0.1
#=GS G3Q2C7_GASAC/1-48       AC G3Q2C7.1
#=GS A6ZXV7_YEAS7/1-102      AC A6ZXV7.1
#=GS F0ZEU8_DICPU/1-76       AC F0ZEU8.1
#=GS Q5SC96_OSTTA/1-67       AC Q5SC96.1
#=GS H2WVB8_CAEJA/37-124     AC H2WVB8.1
#=GS C5PJD9_COCP7/1-84       AC C5PJD9.1
#=GS APC11_HUMAN/1-84        AC Q9NYG5.1
#=GS B8M4B0_TALSN/1-84       AC B8M4B0.1
#=GS B9MXX7_POPTR/1-77       AC B9MXX7.1
#=GS F7I8L7_CALJA/1-84       AC F7I8L7.1
#=GS D8UF69_VOLCA/3-84       AC D8UF69.1
#=GS B8B5F0_ORYSI/1-84       AC B8B5F0.1
#=GS B6SMB2_MAIZE/1-39       AC B6SMB2.1
#=GS G8Y2U7_PICSO/1-97       AC G8Y2U7.1
#=GS C6HH07_AJECH/1-85       AC C6HH07.1
#=GS D8R079_SELML/1-82       AC D8R079.1
#=GS H2AMG3_KAZAF/1-105      AC H2AMG3.1
#=GS E9BZE1_CAPO3/1-82       AC E9BZE1.1
#=GS E9AFS7_LEIMA/1-82       AC E9AFS7.1
#=GS C5WMK0_SORBI/6-89       AC C5WMK0.1
#=GS D2VE26_NAEGR/1507-1577  AC D2VE26.1
#=GS A2QYJ9_ASPNC/62-146     AC A2QYJ9.1
#=GS E6ZUW0_SPORE/1-83       AC E6ZUW0.1
#=GS I1LAY8_SOYBN/1-57       AC I1LAY8.1
#=GS Q6CMU0_KLULA/1-120      AC Q6CMU0.1
#=GS E7QCM6_YEASZ/1-102      AC E7QCM6.1
#=GS E0VZF0_PEDHC/1-84       AC E0VZF0.1
#=GS H9FVK9_MACMU/1-84       AC H9FVK9.1
#=GS G3B6Z6_CANTC/1-92       AC G3B6Z6.1
#=GS A7F5Z0_SCLS1/1-69       AC A7F5Z0.1
#=GS C7YWE3_NECH7/1-79       AC C7YWE3.1
#=GS C6F8R8_PSEMZ/1-38       AC C6F8R8.1
#=GS G0SYQ2_RHOG2/1-109      AC G0SYQ2.1
#=GS Q4RZP4_TETNG/1-84       AC Q4RZP4.1
#=GS F4PCF4_BATDJ/1-80       AC F4PCF4.1
#=GS G8BEI6_CANPC/1-98       AC G8BEI6.1
#=GS G3AIA2_SPAPN/1-94       AC G3AIA2.1
#=GS Q0TXH4_PHANO/37-119     AC Q0TXH4.1
#=GS F0US07_AJEC8/1-85       AC F0US07.1
#=GS G3GXB2_CRIGR/1-45       AC G3GXB2.1
#=GS E2R4W0_CANFA/1-84       AC E2R4W0.1
#=GS Q7KA43_DROME/1-84       AC Q7KA43.1
#=GS I0YWM4_9CHLO/3-85       AC I0YWM4.1
#=GS G0MEB3_CAEBE/52-138     AC G0MEB3.1
#=GS E7Q1Q2_YEASB/1-102      AC E7Q1Q2.1
#=GS C4YN78_CANAW/1-91       AC C4YN78.1
#=GS E4XXP2_OIKDI/1-88       AC E4XXP2.1
#=GS A6RZC0_BOTFB/1-71       AC A6RZC0.1
#=GS A9S3T8_PHYPA/1-85       AC A9S3T8.1
#=GS G0SYP8_RHOG2/1-97       AC G0SYP8.1
#=GS F8PBD6_SERL9/1-91       AC F8PBD6.1
#=GS D3B9P1_POLPA/51-133     AC D3B9P1.1
#=GS I1PAI9_ORYGL/1-84       AC I1PAI9.1
#=GS E1FKZ3_LOALO/48-132     AC E1FKZ3.1
#=GS D8SZQ3_SELML/1-83       AC D8SZQ3.1
#=GS A3GID0_PICST/1-96       AC A3GID0.1
#=GS E9H128_DAPPU/1-86       AC E9H128.1
#=GS H1VJ30_COLHI/1-85       AC H1VJ30.1
#=GS A7TI74_VANPO/1-111      AC A7TI74.1
#=GS C4JFP2_UNCRE/3-35       AC C4JFP2.1
#=GS Q5CNG3_CRYHO/2-86       AC Q5CNG3.1
#=GS Q20052_CAEEL/49-135     AC Q20052.1
#=GS H3A6Y7_LATCH/1-84       AC H3A6Y7.1
#=GS F2U3L5_SALS5/1-82       AC F2U3L5.1
#=GS Q8H306_ORYSJ/1-84       AC Q8H306.1
#=GS Q4PC75_USTMA/1-74       AC Q4PC75.1
#=GS E9EKP6_METAR/1-85       AC E9EKP6.1
#=GS H2QE35_PANTR/1-84       AC H2QE35.1
#=GS G2R786_THITE/1-85       AC G2R786.1
#=GS G2WCE5_YEASK/1-102      AC G2WCE5.1
#=GS Q0DSK3_ORYSJ/1-84       AC Q0DSK3.1
#=GS Q55ZT7_CRYNB/1-108      AC Q55ZT7.1
#=GS B2WAT2_PYRTR/1-25       AC B2WAT2.1
#=GS Q38DY9_TRYB2/1-82       AC Q38DY9.1
#=GS A4S544_OSTLU/1-85       AC A4S544.1
#=GS I1M2W6_SOYBN/1-57       AC I1M2W6.1
#=GS G7KWP0_MEDTR/1-77       AC G7KWP0.1
#=GS E2A9C7_CAMFO/1-84       AC E2A9C7.1
#=GS B6TKR6_MAIZE/1-84       AC B6TKR6.1
#=GS B6Q7W3_PENMQ/1-85       AC B6Q7W3.1
#=GS F9F492_FUSOF/1-72       AC F9F492.1
#=GS C1FIK7_MICSR/1-82       AC C1FIK7.1
#=GS E7KAN2_YEASA/1-102      AC E7KAN2.1
#=GS B2AMU6_PODAN/1-85       AC B2AMU6.1
#=GS H8X5W1_9ASCO/1-98       AC H8X5W1.1
#=GS G0VK26_NAUCC/1-107      AC G0VK26.1
#=GS F4PL87_DICFS/1-82       AC F4PL87.1
#=GS B4H991_DROPE/139-212    AC B4H991.1
#=GS D1ZZG9_TRICA/1-84       AC D1ZZG9.1
#=GS H8ZDQ8_NEMS1/857-933    AC H8ZDQ8.1
#=GS E3XEM6_ANODA/1-75       AC E3XEM6.1
#=GS E1FK78_LOALO/602-658    AC E1FK78.1
#=GS E7KL50_YEASL/1-102      AC E7KL50.1
#=GS E3QIY9_COLGM/1-85       AC E3QIY9.1
#=GS A9T3E0_PHYPA/1-62       AC A9T3E0.1
#=GS B8AM38_ORYSI/1-84       AC B8AM38.1
#=GS F7C530_HORSE/1-37       AC F7C530.1
#=GS H0VPD0_CAVPO/1-84       AC H0VPD0.1
#=GS Q070K4_CPRV/3-77        AC Q070K4.1
#=GS F2Q3U5_TRIEC/1-85       AC F2Q3U5.1
#=GS E9IUU7_SOLIN/11-73      AC E9IUU7.1
#=GS C5GRZ1_AJEDR/32-69      AC C5GRZ1.1
#=GS Q08BH9_DANRE/1-84       AC Q08BH9.1
#=GS E9BSX6_LEIDB/1-82       AC E9BSX6.1
#=GS H3G666_PHYRM/3-87       AC H3G666.1
#=GS G6CRS1_DANPL/1-83       AC G6CRS1.1
#=GS Q2GMG0_CHAGB/1-85       AC Q2GMG0.1
#=GS H0XY84_OTOGA/1-84       AC H0XY84.1
#=GS APC11_PONAB/1-84        AC Q5R8A2.1
#=GS A0BJU5_PARTE/1-81       AC A0BJU5.1
#=GS A1CGA3_ASPCL/1-83       AC A1CGA3.1
#=GS Q172X2_AEDAE/1-83       AC Q172X2.1
D8QKD1_SCHCM/1-89                  .........................................................MKVVIK.N...WHA.....VAQW.RW.D..IGNdd....................................seDDVCG..IC..R..VP.....Y.....E.....G..C......C.....P......A..C..............K........M........P........G........D.......D.............C..........P....L......I..W.....G............E........C............S..HV......FHMHCLLKW...I.G....T...A......S.....S....K....Q....Q...CPMDR.RPWVTA-e........................
H2R0U8_PANTR/1-56                  .........................................................MKVKIK.C...WNG.....VATW.LW.-..VAN........................................DENCG..IC..R..MA.....F.....N.....G..C......C.....P......D..C..............P........L........H........G........E.......S.............I..........S....R......C..L.....G............W........C............P..--......---------...-.-....-...-......-.....-....-....-....-...-----.-------qpvp.....................
G9A002_TORDC/1-100                 .........................................................MKVKLR.E...VHS.....VFAW.TW.H..IPKesqdaha.........................etiddndgDDVCG..IC..R..AS.....Y.....N.....A..T......C.....P......G..C..............K........F........P........G........D.......G.............C..........P....L......V..V.....G............E........C............N..HN......FHVHCIYRW...L.D....T...A......T.....S....R....G....L...CPMCR.QTFQLKK.........................
H2SCN0_TAKRU/1-80                  .........................................................MKVKIR.H...WNG.....VASW.TW.-..VAN........................................DENCG..IC..R..MP.....F.....N.....G..C......C.....P......D..C..............K........V........P........G........D.......D.............C..........P....L......V..W.....G............Q........C............S..HC......FHMHCILKW...L.N....S...Q......Q.....V....Q....Q....Q...CPMCR.QEW----.........................
C4R449_PICPG/68-110                ....................................................ltfcp------.-...---.....----.--.-..---........................................-----..--..-..--.....-.....-.....-..-......-.....-......-..-..............-........-........-........-........-.......-.............-..........-....-......A..I.....G............S........C............H..HS......FHMHCILKW...L.D....T...D......T.....S....K....G....L...CPMCR.QIFTLE-n........................
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H0YZ96_TAEGU/1-84                  .........................................................MRVRVR.S...WHG.....VASW.LW.-..VAN........................................DENCG..IC..R..MA.....F.....N.....G..C......C.....P......D..C..............K........V........P........G........D.......D.............C..........P....L......V..W.....G............Q........C............S..HC......FHMHCILKW...L.N....S...Q......Q.....V....Q....Q....H...CPMCR.QEWKFRE.........................
F6S976_MACMU/1-55                  .........................................................MKVKIK.C...WNG.....VATW.LW.-..VAN........................................DENCG..IC..R..MA.....F.....N.....G..C......C.....P......D..C..............P........L........H........G........E.......S.............I..........S....R......C..L.....G............W........C............P..--......---------...-.-....-...-......-.....-....-....-....-...-----.-------qpv......................
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A6REA3_AJECN/1-83                  .........................................................MKVTIK.E...WNA.....VATW.RW.D..MPE........................................DEVCG..IC..R..VQ.....F.....D.....G..T......C.....P......T..C..............K........Y........P........G........D.......D.............C..........S....L......L..I.....G............K........C............G..HS......FHMHCLLTW...I.G....Q...E......S.....S....K....G....L...CPMCR.QS-----krp......................
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Q3E931_ARATH/1-60                  .......................................................ma------.-...---.....---WgTW.D..-AQ........................................DETCG..LC..R..MP.....F.....D.....A..S......C.....P......D..C..............K........L........P........E........D.......D.............C..........P....Ls....kL..L.....G............D.......yC............L..AM......AIALC----...-.-....-...-......-.....-....-....-....-...-----.-------vvedgnik.................
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C1N1J9_MICPC/1-82                  .........................................................--INIR.R...WQG.....VGVW.TW.N..AGD.......................................kDDVCG..IC..R..VA.....F.....D.....A..C......P.....P......E..A..............K........F........P........G........D.......D.............S..........P....V......V..W.....G............Q........C............G..HA......FHLQCITKW...L.N....S...Q......-.....A....E....Q....R...CPICR.GAWEFK-.........................
C0SJ70_PARBP/1-84                  .........................................................MKVTLK.E...WNA.....VTIW.RW.D..MPE........................................DEVCG..IC..R..VQ.....F.....D.....G..T......C.....P......T..C..............K........F........P........G........D.......D.............C..........S....L......L..I.....G............K........C............G..HS......FHMHCLLTW...I.G....Q...E......S.....S....K....G....L...CPMCR.QSNE---fl.......................
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F4RQ70_MELLP/1-111                 .........................................................MKIKIK.K...VNA.....VAHW.RW.N..LSNekpnqsnpsnptk..............dssqeeadeeeedEELCG..IC..R..SA.....F.....E.....G..C......C.....P......D..C..............K........I........P........G........D.......D.............C..........P....L......I..W.....G............E........C............S..HI......FHMHCLLKW...I.S....E...E......S.....S....K....Q....A...CPMDR.RPW----gmyr.....................
G4LX01_SCHMA/19-102                .......................................................ls--LKIN.H...WFA.....VSAW.KW.-..CTN........................................DDDCG..IC..R..NA.....F.....E.....T..C......C.....A......D..C..............K........L........P........G........D.......D.............C..........P....L......V..W.....G............Q........C............N..HC......FHMHCIIKW...L.N....S...Q......Q.....T....A....Q....H...CPLCR.QDWRFR-e........................
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E7KL50_YEASL/1-102                 .........................................................MKVKIN.E...VHS.....VFAW.SW.H..IPStsdedaan.......................ndpngndedEDVCG..IC..R..AS.....Y.....N.....G..T......C.....P......S..C..............K........F........P........G........D.......Q.............C..........P....L......V..I.....G............L........C............H..HN......FHDHCIYRW...L.D....T...P......T.....S....K....G....L...CPMCR.QTFQLQK.........................
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Q070K4_CPRV/3-77                   .........................................................MSIRVR.R...WVP.....VCAF.SY.D..-AR........................................DDACV..FC..L..RK.....I.....D.....Q..S......Cl...kD......D..C..............L........R........G........E........R.......H.............C..........G....L......V..F.....C............N........N............S..HC......FHYHCA---...-.-....-...-......-.....-....-....-....-...-----.-------gsfdacvlcgarl............
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Q08BH9_DANRE/1-84                  .........................................................MKVKIK.Q...WNG.....VASW.LW.-..VAN........................................DENCG..IC..R..AS.....F.....N.....G..C......C.....P......D..C..............K........V........P........G........D.......D.............C..........P....L......V..W.....G............Q........C............S..HC......FHMHCILKW...L.N....S...Q......Q.....V....Q....Q....Q...CPMCR.QEWKFKE.........................
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H3G666_PHYRM/3-87                  .........................................................MKVTVK.R...WHG.....VATW.TW.G..V-D........................................EECCG..IC..R..YA.....F.....E.....A..C......C.....P......D..C..............T........M........P........G........D.......G.............C..........P....P......V..W.....G............A........C............N..HA......FHMHCLMKW...L.E....S..lQ......S.....M....R....Q....H...CPMCR.QDWKFR-n........................
G6CRS1_DANPL/1-83                  .........................................................MKVTIK.S...WTG.....VATW.RW.-..IAN........................................DDNCG..IC..R..MP.....F.....D.....S..C......C.....P......D..C..............K........L........P........G........D.......E.............C..........P....L......V..W.....G............A........C............S..HC......FHIHCIVKW...L.H....S...Q......-.....P....Q....Q....Q...CPMCR.QDWKFN-n........................
Q2GMG0_CHAGB/1-85                  .........................................................MKVTIK.K...WNA.....VATW.RW.D..IPE........................................DDVCG..IC..Q..VH.....F.....D.....G..T......C.....P......T..C..............K........Y........P........G........D.......D.............C..........P....L......L..S.....G............K........C............G..HN......FHMHCILEW...I.K....Q...D......S.....A....K....G....Q...CPMCR.QRFEW--te.......................
H0XY84_OTOGA/1-84                  .........................................................MKVKIK.C...WNG.....VATW.LW.-..VAN........................................DENCG..IC..R..MA.....F.....N.....G..C......C.....P......D..C..............K........V........P........G........D.......D.............C..........P....L......V..W.....G............Q........C............S..HC......FHMHCILKW...L.H....A...Q......Q.....A....Q....Q....H...CPMCR.QEWKFKE.........................
APC11_PONAB/1-84                   .........................................................MKVKIK.C...WNG.....VATW.LW.-..VAN........................................DENCG..IC..R..MA.....F.....N.....G..C......C.....P......D..C..............K........V........P........G........D.......D.............C..........P....L......V..W.....G............Q........C............S..HC......FHMHCILKW...L.H....A...Q......Q.....V....Q....Q....H...CPMCR.QEWKFKE.........................
A0BJU5_PARTE/1-81                  .........................................................MKVKIK.E...WNA.....VASW.IW.S..LD-........................................TDRCT..IC..Q..LA.....F.....E.....Q..P......C.....P......R..C..............K........L........P........G........D.......E.............C..........P....P......V..T.....G............A........C............N..HH......FHLHCIVRW...T.E....E...-......-.....-....Q....D....Y...CPLDR.QKWKVK-n........................
A1CGA3_ASPCL/1-83                  .........................................................MKVTIK.E...WNA.....VATW.RW.D..MPE........................................DEVCG..IC..R..VQ.....F.....D.....G..T......C.....P......T..C..............K........F........P........G........D.......D.............C..........S....L......L..L.....G............K........C............G..HS......FHMHCLMTW...I.Q....Q...E......S.....S....K....G....L...CPMCR.QS-----ksh......................
Q172X2_AEDAE/1-83                  .........................................................MKVTVK.S...WMG.....VAVW.KW.-..LAN........................................DDNCG..IC..R..MA.....F.....E.....G..C......C.....P......D..C..............S........L........P........G........D.......D.............C..........P....L......V..W.....G............S........C............S..HC......FHMHCIVKW...L.N....S...Q......-.....A....N....Q....Q...CPMCR.QTWKFN-d........................
#=GC seq_cons                      .........................................................MKVpIp.p...Wpu.....VAsW.pW.t..hsp........................................D-sCG..IC..R..hs.....F.....-.....G..s......C.....P......s..C..............K........h........P........G........D.......D.............C..........P....L......l..h.....G............p........C............s..Hs......FHhHCIh+W...l.p....p...p......p.....s....p....t........CPMCR.ppaph...........................
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