KEGG   Pyrolobus fumarii: Pyrfu_1976
Entry
Pyrfu_1976        CDS       T01620                                 
Name
(GenBank) homocitrate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
pfm  Pyrolobus fumarii
Pathway
pfm00290  Valine, leucine and isoleucine biosynthesis
pfm00620  Pyruvate metabolism
pfm01100  Metabolic pathways
pfm01110  Biosynthesis of secondary metabolites
pfm01210  2-Oxocarboxylic acid metabolism
pfm01230  Biosynthesis of amino acids
Module
pfm_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:pfm00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    Pyrfu_1976
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Pyrfu_1976
Enzymes [BR:pfm01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     Pyrfu_1976
SSDB
Motif
Pfam: HMGL-like AsnC_trans_reg FtsX_ECD NapD ACT_4 Lipase_GDSL_2 AP_endonuc_2 AlkA_N Radical_SAM SurA_N_2 CinA_KH
Other DBs
NCBI-ProteinID: AEM39829
UniProt: G0EDM5
Position
1834109..1835569
AA seq 486 aa
MQGMIRREEWGIGGPKPERIRVGLLDSTLREGEQTPGVSFTVEQKVEIAKLLSEAGVQMI
EAGHPAVAPDVYEAVKRIIQLKKEGVIRSEIVAHSRAVKRDIEVAAELEPDRIAIFYGVS
DIHLRYKHRVSREEALSIIGEMVEYAKQHGVKVRFTAEDATRADYDYLVEVVKTARDAGA
DRVSIADTVGIATPAFMRRLFESLTRDAPGVEFDVHAHNDLGLATANSLAAVEGGATIIH
VTVNGLGERAGITPLHEAAVALKVHYGIEVIDLKLIPKLSRLVERYSGIPVPPNTPVVGD
NAFTHKAGVHVAGILANPETYEPYPPEMVGRTRDYVIDKYTGKKAVKARLEKLGVTVTDK
ELEEIVRRIKARPDIRYLRDEDLLEIASEVMGKPLALTAPRGVEAIVLVKTNSNVYTTSI
ARRLSIIPGVAEVMEVTGDNDIVLRIQARNTEQLNQVIEQVRTIPGVQSTYTMLILKKST
GEQKEA
NT seq 1461 nt   +upstreamnt  +downstreamnt
ttgcagggtatgatccgccgcgaggagtggggcataggcggaccaaaaccggagcgcatt
cgcgttgggctgctagactccacgctccgtgagggtgagcagactccaggcgtgagcttc
accgtcgagcagaaggtcgagatagctaagcttctcagcgaggctggcgtacagatgatt
gaggctggtcatcctgccgtcgcgccagatgtctacgaggctgtcaagaggataatccag
ttgaagaaggagggcgtaatacgctcagagatagtcgctcactcgcgagccgtcaagagg
gatatcgaggttgcagcggagctggagccagaccgcatagccatcttctacggcgttagc
gacatccaccttaggtataagcaccgtgtttcgcgcgaggaggccctctcaatcatagga
gagatggtggagtacgcgaagcagcacggtgtgaaggttagatttacggcggaagacgcc
accagggccgactacgattacctcgtagaggttgtgaagactgctagggatgccggggcg
gatagggtatcaatagcggataccgtggggatagccacacctgccttcatgaggaggttg
ttcgagagcctaaccagggacgccccgggagtagagttcgacgtacatgcacacaatgac
ctcggcctcgcgacggccaactcgctcgctgctgtagagggaggcgccaccataatccac
gttactgtgaacggcttgggcgagagagccggaataaccccgctccacgaggcggcagtc
gcgctcaaggtgcactacggaatcgaggttatagacttgaagctcatcccgaagctatcc
aggctggtcgagaggtactcgggtatacccgtgccgccaaacacaccggttgtcggcgac
aacgcgttcacgcacaaggccggagtccacgtcgctggtatactcgccaaccccgagacc
tacgagccctacccgccagagatggtggggagaaccagagactacgtgatagacaagtac
actggcaagaaggctgtgaaagccaggctcgagaagctaggcgtgacggtcaccgacaag
gagcttgaagagatagtaaggaggattaaagcaagacccgacatacgctacctgcgcgac
gaggaccttctagagatagcgagcgaggtaatgggcaagccactagcgctaacagcccca
agaggcgtagaagccatagtcctcgtaaagacgaacagcaacgtatacacaacatccata
gccagaaggctaagcatcataccaggcgtcgcagaggtaatggaggtgacaggcgataac
gacatagtactacgcatacaagccaggaacactgaacaactaaaccaagtgatagaacag
gtacgcaccataccaggcgtacaatcgacatacacgatgctaatactcaagaagagcacg
ggagagcagaaagaagcctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (71)   
   KEGG ORTHOLOGY (1)   
   RefGene (68)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (11)   
   Pfam (11)   
All databases (100)   

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