| Entry |
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| Definition |
3-isopropylmalate dehydratase large subunit (EC:4.2.1.33)
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| Orthology |
| 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC: 4.2.1.33 4.2.1.35] |
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| Organism |
pfu Pyrococcus furiosus DSM 3638
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| Pathway |
| Valine, leucine and isoleucine biosynthesis | | C5-Branched dibasic acid metabolism | | Metabolic pathways | | Biosynthesis of secondary metabolites | | 2-Oxocarboxylic acid metabolism | | Biosynthesis of amino acids |
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| Module |
| Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate |
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| Class |
Metabolism; Carbohydrate metabolism; C5-Branched dibasic acid metabolism [PATH: pfu00660]
Metabolism; Amino acid metabolism; Valine, leucine and isoleucine biosynthesis [PATH: pfu00290]
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| SSDB |
    |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: UniProt: |
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| Position |
902558..903832
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| AA seq |
424 aa  
MGGMTIAEKILATHAGKEEVKPGEIVLAKVDFMFGNDVTTPLAIKTFRKIGVEKVFDPER
IAIVLDHFTPNKDIKAAEQCKFSREFAREQGIKWFFEGGNVGVEHCLLPELGLVLPGELI
IGADSHTCTYGALGAFATGVGSTDLAVAMATGEAWFRVPETIKFVYEGDLQPWVTSKDLI
LYTIGDIGVNGALYKVMEFSGEVIEKLSVEQRMTMTNMAIEAGAKTGIIEPDKKTIEYVK
GRAKREYKIYKSDEDAKYYKVIEYDVSKIEPQVAFPHLPENTVPISKAAKMNIKIDQVVI
GSCTNGRLEDLRMAAEVLEGQKVAPWVRLIILPCSPTVYFKAMKEGLLEIFLEAGAVIGP
PTCGPCLGGHMGILASGERAVSTTNRNFVGRMGHPKSEVYLASPYVAAASAILGRIASPE
EVVK |
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| NT seq |
1275 nt  +upstreamnt +downstreamnt
atgggcggaatgacaatagctgaaaaaattttggcaactcatgccggaaaggaagaggta
aaacctggagagatagttttggcaaaagtggacttcatgtttgggaatgatgtaacaacc
cccttagccataaaaacgtttagaaagattggagtggagaaggtttttgacccagaaaga
atagcaatagttttagatcacttcactccaaataaagatatcaaagctgcggagcaatgt
aaattctcacgagaatttgccagagaacagggaatcaagtggttctttgagggaggaaac
gttggtgtcgagcattgtttactccctgagttaggattagttctcccaggagagctaatt
attggagcagattcccacacttgcacttatggagccctgggtgcctttgcaactggagtt
ggtagtactgacttagcagttgcaatggcaacaggagaggcgtggttcagggttcccgaa
acgataaaattcgtttatgaaggagaccttcaaccctgggtaactagtaaggatctcata
ctttacacaatcggagacataggggttaatggagccctctacaaagtcatggaattttcg
ggagaagttatagagaagctttccgtggaacagaggatgacgatgactaatatggccata
gaggccggagcaaagactgggataatagagccggataagaagactatagagtacgtaaag
gggagggccaagagagagtacaagatctacaagagcgatgaagatgcaaagtactacaag
gttattgagtatgacgttagtaaaattgaacctcaagttgcctttccacacttacccgaa
aacacggttcccatcagcaaggccgcaaagatgaacataaagatagaccaagttgtcatt
ggctcatgtacgaatggtaggttggaagaccttagaatggccgctgaagttttagaaggc
cagaaagtggccccctgggtaaggcttatcattcttccatgttcaccgactgtgtatttc
aaggcaatgaaggagggcctcttggagattttcctggaggcaggagctgttatagggcct
ccaacttgtggaccgtgcctaggaggtcacatgggtattctggcgagtggtgagagagct
gtatctacaacaaacaggaactttgttggaagaatgggtcacccaaagagcgaagtttac
ttggcaagtccctatgtagctgcagcttcggctattcttggtagaattgcctctccagag
gaggtggtaaaatga |
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