KEGG   Pantholops hodgsonii (chiru): 102315876Help
Entry
102315876         CDS       T02909                                 

Gene name
GAD2
Definition
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Orthology
K01580  
glutamate decarboxylase [EC:4.1.1.15]
Organism
phd  Pantholops hodgsonii (chiru)
Pathway
Alanine, aspartate and glutamate metabolism
beta-Alanine metabolism
Taurine and hypotaurine metabolism
Butanoate metabolism
Metabolic pathways
GABAergic synapse
Type I diabetes mellitus
Module
GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:phd00001]
 Metabolism
  Carbohydrate metabolism
   00650 Butanoate metabolism
    102315876 (GAD2)
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    102315876 (GAD2)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    102315876 (GAD2)
   00430 Taurine and hypotaurine metabolism
    102315876 (GAD2)
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    102315876 (GAD2)
 Human Diseases
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    102315876 (GAD2)
Enzymes [BR:phd01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.15  glutamate decarboxylase
     102315876 (GAD2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 584 aa AA seqDB search
MASPGSSFWSFGSEDGSGDPENPGTARAWCQVAQKFTGGIGNKLCGECLRGCPREGGGHG
QAPRATSRKAACACNQKPCSCPKAEVNYAFLHATDLLPACDGERPTLAFLQEVMDILLQY
VVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILMHCQTTLKYAIKTGHPRYFNQ
LSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSP
GGAISNMYAMLIARFKMFPEVKEKGMAAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVIL
IKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWM
HVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQM
HASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHIDKCLELAEYL
YNIIKNREGYEMVFDGKPQHTNVCFWYVPPSLRVLDNNEERLSRLSKVAPVIKARMMEHG
TTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL
NT seq 1755 nt NT seq  +upstreamnt  +downstreamnt
atggcatctcccggctccagcttttggtccttcggatctgaagatggctcgggggatccc
gagaaccccggcacagccagggcctggtgtcaggtggcccagaagttcacaggcggcatc
ggaaacaaactgtgcggtgagtgcctgcgcgggtgcccgagggaaggaggcggacatggc
caggcaccgcgngccacctcccgcaaagccgcctgcgcctgcaaccagaagccctgcagc
tgccccaaagcggaggtcaactatgcatttctacacgcaacagatctgctgccagcgtgt
gatggagaaaggcccactttggcgtttctgcaagaggttatggacattttgcttcagtat
gtggtgaagagttttgatagatcaaccaaagtgattgattttcattaccctaatgagctt
cttcaagaatataattgggaattggcagaccaaccacaaaatttggaggaaattttgatg
cattgccaaacaactctaaaatatgcaattaaaacagggcatccaaggtatttcaatcaa
ctttctaccggactggatatggttggattagcagcagactggctgacatcaacagcaaac
actaacatgttcacctatgaaattgctccagtatttgtgcttttggaatatgtcacgcta
aagaaaatgagagaaatcattggctggcctgggggctctggtgatgggatattttctcct
ggtggcgctatatccaacatgtacgccatgctgattgcgcgctttaagatgttcccggaa
gtcaaggagaaagggatggctgccgtccccaggctcattgccttcacgtctgagcatagc
catttttctctcaagaagggagctgcagccttgggcattggaacagacagtgtgattctg
attaaatgtgatgaaagggggaaaatgatcccatctgaccttgaaagaaggatccttgaa
gccaaacaaaaagggtttgtccctttccttgtgagcgccacggctgggaccactgtgtat
ggagcctttgaccccctgttagcggttgctgacatttgcaaaaagtataagatctggatg
cacgtagatgcagcttggggtgggggattactgatgtctcggaaacacaagtggaaacta
agcggcgtggagagggccaactctgtgacctggaatccgcataagatgatgggcgttcct
ttgcagtgctctgctctcctggttagagaagagggattgatgcagagttgcaaccagatg
catgcctcctacctcttccaacaagataaacactatgacctgtcctatgacactggagac
aaggccttgcagtgtggacgccacgttgatgtttttaaactctggctaatgtggagggca
aaggggaccacaggatttgaggcacatattgataagtgtttggagctggcggagtattta
tacaatatcatcaaaaaccgagaaggttatgaaatggtgtttgatggaaagcctcagcac
accaacgtctgcttctggtacgtacctccgagcttgcgtgtcctggacaacaatgaagag
agactgagccgcctctccaaggtggctcctgtgattaaagccaggatgatggagcatggg
accacgatggtgagctaccagcccttgggcgacaaggtcaacttcttccgcatggtcatc
tcaaaccccgcagcaactcaccaagacattgacttcctgattgaagaaatagaacgcctt
ggacaagatttataa

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