KEGG   Pantholops hodgsonii (chiru): 102333324Help
Entry
102333324         CDS       T02909                                 

Gene name
PIK3CD
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
phd  Pantholops hodgsonii (chiru)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:phd00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102333324 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102333324 (PIK3CD)
   04015 Rap1 signaling pathway
    102333324 (PIK3CD)
   04012 ErbB signaling pathway
    102333324 (PIK3CD)
   04370 VEGF signaling pathway
    102333324 (PIK3CD)
   04630 Jak-STAT signaling pathway
    102333324 (PIK3CD)
   04668 TNF signaling pathway
    102333324 (PIK3CD)
   04066 HIF-1 signaling pathway
    102333324 (PIK3CD)
   04068 FoxO signaling pathway
    102333324 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    102333324 (PIK3CD)
   04024 cAMP signaling pathway
    102333324 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    102333324 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    102333324 (PIK3CD)
   04152 AMPK signaling pathway
    102333324 (PIK3CD)
   04150 mTOR signaling pathway
    102333324 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102333324 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    102333324 (PIK3CD)
  Cellular commiunity
   04510 Focal adhesion
    102333324 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102333324 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    102333324 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    102333324 (PIK3CD)
   04660 T cell receptor signaling pathway
    102333324 (PIK3CD)
   04662 B cell receptor signaling pathway
    102333324 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    102333324 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    102333324 (PIK3CD)
   04670 Leukocyte transendothelial migration
    102333324 (PIK3CD)
   04062 Chemokine signaling pathway
    102333324 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    102333324 (PIK3CD)
   04915 Estrogen signaling pathway
    102333324 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    102333324 (PIK3CD)
   04917 Prolactin signaling pathway
    102333324 (PIK3CD)
   04921 Oxytocin signaling pathway
    102333324 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    102333324 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102333324 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102333324 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102333324 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    102333324 (PIK3CD)
   04722 Neurotrophin signaling pathway
    102333324 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102333324 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    102333324 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102333324 (PIK3CD)
   05205 Proteoglycans in cancer
    102333324 (PIK3CD)
   05203 Viral carcinogenesis
    102333324 (PIK3CD)
   05210 Colorectal cancer
    102333324 (PIK3CD)
   05212 Pancreatic cancer
    102333324 (PIK3CD)
   05214 Glioma
    102333324 (PIK3CD)
   05221 Acute myeloid leukemia
    102333324 (PIK3CD)
   05220 Chronic myeloid leukemia
    102333324 (PIK3CD)
   05218 Melanoma
    102333324 (PIK3CD)
   05211 Renal cell carcinoma
    102333324 (PIK3CD)
   05215 Prostate cancer
    102333324 (PIK3CD)
   05213 Endometrial cancer
    102333324 (PIK3CD)
   05222 Small cell lung cancer
    102333324 (PIK3CD)
   05223 Non-small cell lung cancer
    102333324 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102333324 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102333324 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102333324 (PIK3CD)
   05166 HTLV-I infection
    102333324 (PIK3CD)
   05162 Measles
    102333324 (PIK3CD)
   05164 Influenza A
    102333324 (PIK3CD)
   05161 Hepatitis B
    102333324 (PIK3CD)
   05160 Hepatitis C
    102333324 (PIK3CD)
   05169 Epstein-Barr virus infection
    102333324 (PIK3CD)
   05146 Amoebiasis
    102333324 (PIK3CD)
   05145 Toxoplasmosis
    102333324 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    102333324 (PIK3CD)
Enzymes [BR:phd01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102333324 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 940 aa AA seqDB search
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKTLPLILALTWLPX
LSGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGPG
TLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTL
QVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRT
KPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSSS
EVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAWA
NLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVISLPEVAPH
PVYYPSLDKILELGRLGEHGRFTEEEVSWGPWAVGVDLAMLYLLCSWPELPVLSALELLD
FSFPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIG
HFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQ
KTPKPQAKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYS
NEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGL
IEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQ
GKTSNSEKFERFRGYCETAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLAL
GKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
NT seq 2823 nt NT seq  +upstreamnt  +downstreamnt
atgccccccggggttgactgccccatggaattctggaccaaggaggagaatcagaatgtg
gcagttgatttcttgctgcccacaggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcactatcaagaagaccctgcccctgatcctggcgctgacctggctccctngc
ctctcaggcctccacgagtttgactccttgcaagacccggaggtgaatgacttccgaggc
aagatgcgccagttctgcgaggaggcggctgcccgcaggcagcagctgggctgggaggcc
tggctgcagtacagcttccctctgcagttggagccctcggcgcggagctgggggccgggc
accctgcgcgtccccaatcgggccctcctggtcaatgtcaagtttgagggcagcgaggag
agcttcaccttccaggtatccaccaaggatgtgcccctggcactgatggcttgcgccctc
cgaaagaaggccacggtgttccggcagccgctggtggagcagcctgaggactacacactg
caggtgaacggcaagcatgagtacctgtatggcagctaccccctctgccagttccagtac
atctgcagctgcctgcacagtgggctgaccccccacctgaccatggtgcactcctcctcc
atcctcgccatgcgggacgagcagagcaaccctgccccccaagtccagaagccacgcacc
aaaccgccccccatccccatgaagaagccctcctccgtgtccctgtggtccctggagcag
cctttctacatcgagctgatccagggcagcaaagtgaatgccgacgagcggatgaagctg
gtggtgcaggccgggctcttccacggcaatgagacactatgcaagacggtgtccagctca
gaggtgagcgtgtgttcggagcccgtttggaagcagcggctggagtttgacatcaacatc
tgtgacctgccccgcatggcccggctctgcttcgcgctttacgccgtgatcgagaaggcc
aagaaggcccgctccaccaagaagaagtccaagaaggcggactgccccattgcttgggcc
aacctcatgctgtttgactacaaggaccagctcaagacgggcgagcgctgtctctacatg
tggccctctgtcccagacgagaaaggggagctactgaacccctgtgggaccgtgcggagt
aaccccaacactgagagtgcggccgccctggtcatctctctccctgaggtggcccctcac
cctgtatactacccttccctggacaagatcctggagctggggcggcttggagagcacgga
cgcttcacggaggaggaggtgagctgggggccgtgggcggtgggtgtggacctggctatg
ctctacctgctctgctcctggcctgaactgcccgttctgagcgccctggagttgctagac
ttcagcttccccgaccgccacgtgggctccttcgccatcaagtccctgcggaaactaacg
gacgacgagcttttccagtacctgctgcagctggtgcaggtgctcaagtacgagtcctac
ctcgactgcgagctgaccaaattcctgctggaccgggccctggccaatcgcaggatcggc
cacttcctcttctggcacctccgctccgagatgcatgtgccgtcggtggctctgcgcttc
ggcctcatcatggaagcctactgccggggcagcacccaccacatgaaggtgctgatgaag
cagggggaagcgctgagcaaactgaaggccctcaatgacttcgtcaaagtgtgctcccag
aagacccccaaaccccaggccaaggagctgatgcacctttgcatgcgccaggaggcctac
ctggaggctctctcccacctgcagtccccgctcgaccccagcaccctgctggctgaggtc
tgcgtggagcagtgcaccttcatggactccaagatgaaacccctgtgggtcatgtacagc
aacgaggaggcaggcagcgacggcaccgtgggcatcatctttaagaatggggacgacctc
cgccaggacatgctgaccctgcagatgatccagctcatggacattctgtggaagcaggag
ggcttggacctgaggatgaccccctacggctgcctctccactggggaccgcacaggcctt
attgaggtggtgcttcactcggataccattgccaacatccagctgaacaagagcaacatg
gcggccacggccgccttcaataaggatgctctgctcaactggctcaagtccaagaaccct
ggggaggccctggatcgagccattgaggagttcaccctctcctgtgctggctactgtgtg
gccacctatgtgctgggcattggcgatcgccacagcgacaacatcatgatccgagagaac
gggcagctgttccacattgatttcggccactttctggggaatttcaagaccaagtttgga
atcaaccgtgagcgggtcccattcatcctcacctatgactttgtccacgtgatccagcag
gggaagacgagtaatagtgagaagtttgaaaggttccggggctattgtgagacggcctac
accatcctgcggcgacatgggctccttttcctccacctctttgccctgatgcgggcggca
ggactgcctgagctcagctgctccaaagacatccagtatctcaaggattctctggcattg
gggaaaacggaggaggaggctctgaagcacttccgagtgaagtttaatgaggccctccgg
gaaagctggaaaaccaaagtgaactggctggcccacaacgtgtccaaagataacaggcaa
taa

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