KEGG P.horikoshii: PH0414

Pyrococcus horikoshii: PH0414

Entry

PH0414 CDS P.horikoshii

Definition dTDP-glucose 4,6-dehydratase

Orthology K01710 dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]

Pathway pho00521 Streptomycin biosynthesis
pho00523 Polyketide sugar unit biosynthesis

Class Metabolism; Biosynthesis of Polyketides and Nonribosomal Peptides;
Polyketide sugar unit biosynthesis [PATH:pho00523]
Metabolism; Biosynthesis of Polyketides and Nonribosomal Peptides;
Biosynthesis of vancomycin group antibiotics
Metabolism; Biosynthesis of Secondary Metabolites; Streptomycin
biosynthesis [PATH:pho00521]

SSDB

Motif Pfam: Epimerase 3Beta_HSD RmlD_sub_bind NAD_binding_4
Polysacc_synt_2 adh_short KR NmrA TrkA_N Saccharop_dh
Semialdhyde_dh

Other DBs NCBI-GI: 14590332
NCBI-GeneID: 1444312
NITE: PH0414
UniProt: O58151

Structure

PDB: 2HUN

Position 377637..378647

AA seq 336 aa
MHSMKLLVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPRYTFVK
GDVADYELVKELVRKVDGVVHLAAESHVDRSISSPEIFLHSNVIGTYTLLESIRRENPEV
RFVHVSTDEVYGDILKGSFTENDRLMPSSPYSATKAASDMLVLGWTRTYNLNASITRCTN
NYGPYQFPEKLIPKTIIRASLGLKIPIYGTGKNVRDWLYVEDHVRAIELVLLKGESREIY
NISAGEEKTNLEVVKIILRLMGKGEELIELVEDRPGHDLRYSLDSWKITRDLKWRPKYTF
DEGIKKTIDWYLKNEWWWKPLVDERILHPTPWKLKW

NT seq 1011 nt +upstreamnt +downstreamnt
gtgcattcgatgaaactcttagtgactggaggaatggggttcattgggagcaacttcatc
cgctatatcctagaaaagcatccagactgggaagtaataaacatagacaagctaggatat
ggctcaaatccggctaacctaaaagatctggaagatgaccctaggtacaccttcgtgaaa
ggtgacgtagctgactacgagctcgttaaggaattggtgaggaaagttgatggggtagtg
cacctagcagcagagagtcacgtcgataggagcatttcttcgcctgaaatatttctccac
agcaacgttataggaacgtatactctcctcgagtcaataaggagagaaaaccccgaagtt
agatttgtacacgtgagtactgatgaagtctacggcgatattctgaagggttcatttacg
gaaaatgaccgtttaatgccctcctccccatattctgcgacgaaagcggccagcgatatg
ttagttctcgggtggacaaggacttacaacctgaatgcatcgataacgaggtgcacaaac
aactacggcccctatcaattcccggagaagctcattccaaagactataataagggcgagc
ttggggcttaagatacccatatatggtactgggaagaacgttagggattggctatatgtg
gaggatcacgttagagcaattgagcttgtcctgctcaaaggtgaatccagggagatatac
aatatctcagctggagaagagaagacaaacctggaagtagttaagattattttaaggctc
atgggcaaaggcgaggagttaatagagttagttgaggatagaccagggcatgacttacgc
tattccctggattcttggaagataaccagagacctaaagtggagaccaaagtacactttt
gatgagggaattaagaagaccattgattggtatttaaagaatgagtggtggtggaagcct
ttagttgatgagaggatactccacccaactccctggaaactaaaatggtag

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   NITE (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   GenBank (1)   
   EMBL (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (11)   
   Pfam (11)   
All databases (25)

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