KEGG T01094: PKH

Plasmodium knowlesi: PKH_123560

Entry

PKH_123560 CDS T01094

Definition

biotin carboxylase subunit of acetyl CoA carboxylase (EC:6.3.4.14)

Orthology

K11262

acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]

Organism

pkn Plasmodium knowlesi

Pathway

pkn00061	Fatty acid biosynthesis
pkn00620	Pyruvate metabolism
pkn00640	Propanoate metabolism
pkn01100	Metabolic pathways

Class

Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:pkn00620]
Metabolism; Carbohydrate metabolism; Propanoate metabolism [PATH:pkn00640]
Metabolism; Lipid metabolism; Fatty acid biosynthesis [PATH:pkn00061]

SSDB

Motif

Pfam:

Carboxyl_trans CPSase_L_D2 CPSase_L_chain Biotin_carb_C Biotin_lipoyl ATP-grasp_4 ATPgrasp_Ter Dala_Dala_lig_C ATP-grasp ATP-grasp_3

Other DBs

NCBI-GI:

NCBI-GeneID:

GeneDB:

UniProt:

Position

12:complement(join(1481244..1481493,1481643..1481857,1481969..1490269))

AA seq 2921 aa
MVNGLTGAFSLVLLFQNFVEPIKYNNTNCYVHMHNNVNRNNLINTETREVYQSRIKGTKN
ILHESYRNRYVPLFVSKGTELLSSFFKNNRRRSGDNSTNISKNGKKSSPSSFKENNSPRA
TICRSSSGRKWDSSKGTAEQNVAHEKECTEQKRTIEELTDELLSSLSSHTDEGFMSVTSI
DRNNRNYIPGKTHHPRNMNNENGKSDDNLYTNSASYSPGKMSDVFSNGDFAKESVRRKNN
IEDNLTFMMDLIKESSPIPYKGGDVIIPQDRSGDVLMDGRRLNKGKVKKRKKHLNRLYYS
FRGHNDFLSRKEGTHGGDVCLGPVSNSPVQQKERNPLQGRVHRTKAQNFHDGENDFASPA
IHSSDSNDFLTYEEKERAKEKAYREYTKYIEERRYPYFNFVKNKNGKIIKKLLIANNGMA
AMKCILSIKEWLFKSFSEENLIKIIVLATEEDISSNAKYISFANKVIKVPPGKNSNNYAN
VQLIVDIAKKEQVDAVWPGWGHCSENPLLSTMLEKENIIFIGPTGDVMEALGDKISANIL
AQSVNVPVVKWSGDSIRVDNFDKKISEDIYNKSTIHSLDACIKECQRIGYPVMIKASQGG
GGKGIRKVENEEEIKKAYTQVQMELPNSPIFLMKVCSNVRHIEIQVVGDMYGNVCSLSGR
DCTTQRRFQKIFEEGPPSVVPPNIFREMEKASIRLTKMIKYRGAGTIEYLYDQEKQTYFF
LELNPRLQVEHPVSEGITNTNLISIQLQVAMGIPLQNIDDIRRLYRIGEGHGDASFRSPI
GAFHRLGSPCDYTPPPNGTSESSGGASIDCDDGSKNGGDQTNEFSPARAEQMDPFDFYNN
RPHVSNHVIAARITAENSNDSFKPTSGKVKRIHFQNSNDVWGYFSINDGSVHEFSDSQIG
HIFAKGETREVARKNLILALRKLNIDGEIKTGTKYLAKILECKPFIENNITTNWLDTIIE
KKKYIYYSAVHIIILCATIFKLLIHFIKEKEVIEDALNREDIGIKPQEDAFTNLKREVKN
AYVFDIVFENVRYNFKGYNTGENLYTLKINGQEIEVLADYDKKNNKIFASFFNHTYLYTC
LEDSLGIHMHLDKDSIFIPKISNPFHLVSNTNGKIVKYLIKDGEKIEKNEDYIEVEAMKM
IMTFKSTEKGILRHKMSEGTIVKIGDLLGVIEENSLDSNTQRGEKNEIKTFTGHLDLSNK
YAYELEEASRLSYPIKGENVMLGSVPTYESTEGVWPISDQKMGRGHLYKGTANCDDEGTL
RVVPNHASNEMHRLSENAAGTQHGMDATKSEDTSFFSSFEQDEVSSKEGITKNRLFLKQR
KNIFRLFASKKTSDKKEHTAASYVNEKFNSFKEYLTSLSSSDERSAAPTSVSTSVKVEAD
VDESAQMGVDVAAESNKSYSNSESRECANESSSAHTVNDESGSAHQGKNSTGLNSTCENS
STSERRNRNENSSSEVVSTRNASNEKTSNEGTLNWGTENKEASKTSSKSSSKSSSKSASK
SASEGTFKCTSNSRTQVGGDTPGVDSPGGHPSTAEEPRKEQFLLDIPNMKRVEYLLKGYE
QDYEECFNQLVKNKRNFIPNIIYILKKFIEYNSLFAEEENITQVEVYDILHTKFRNEKKK
KYEIAHAYTYNYLSIKFVLLVLKYLLDSGLSSLSEVPNDLLDKLKVITSFRGKLFGNIIL
LTRAIVHMAERMRLVDLVKGALNDRSHLSGDKISQLEEHIKIKQSIITRSRLGQFSTDTF
TPSSTLISYRNYCERVVNTFLGSPSDVHMFLPSLFTTENKSTLLEIYVQNLYKHFDIKTE
LVRDDCLKFFINNSEEENLLILNEKGTVYVDEFMDKGGMNPTDGRIKSIHIINRNEHFPN
DYEGSVEHIKNMCKHLYIYHYFGERYGDVYEWGGEGYSGEEIHSGRRTNLLPYQRYIFSF
EKNCQNYDLESVDEKIFKGTKVFLGMYKKNKKIQSLFAERVIHVCNLPKGEVSVLRETPP
KGENIMARQDLSHVMEKEWFQDALTEEFKEAVNDIKIARLNPKVQDARLSSYITYHIVLD
EVKDNDADELNIIVEALKNFLNRHNEFLLENYVNDVYACVYRKGGESAKGRLKLEPKKIL
RLHVLFDGENNVIEEVGSVPIFDVDALYLKRKRARDIDTLYAYDFVKAINISLNRMNNGG
SKDLFTYVNSVKEFKLDLEALHGVEDSKAEGNIAKQSMCHTGGLFPRHDGLSEDEVKIRN
ALYLSDKLNVGQNKLSVIGLLMNVKTIEYKEGRDVIFIINDITTHGGSFSVVEDQLFYAI
SSYAREKKIPRIYISCNSGARIGLYNFLMDKIQVSWKDEEKKELGYDYIYITEEVKNKIS
KEDIIFLKEVIKNGEKRYIIEGIVGNLNNHIGVENLRGSGLIAGETSKAYDEIFTLSYVT
GRSVGIGAYLVRLGKRTIQKKGSSLLLTGFNALNKILGEKVYVSNEQLGGVKIMMRNGIS
QLEAHNDQDGVDKIFKWLSYVPKTSDHYYDVIEEVRQKTSGNSYYEQGKVESAEREVKKL
FEEEEKPTSEKEPPKVYFQRINDIDMDNIQNADVIELIKGTDTKQGFLDKNSYFEYMNEW
GKGIITGRGKLGSIPVGIIAVNRNLVTQDVPCDPALKTKAVRSTQAPCVFFPDNSYKTAQ
SIEDFNKENLPLFVFANWRGFSGGTMDMFNSILKFGSMIVNQLVNYKHPVFVYIPIWGEL
RGGSWVVVDETLNSQIIEMYADTNSKGGILEPPGIVEVKFRLPEIRKLMHGIDSSIITLD
KRLSEAQEDGVSKIKQEIEDKEKELLPFYLQVCHRYADLHDVSKCMKSKGVIRKIVPWEK
ARSFFYYRLVRRLLMSTLSRKYGTSLTQSEEFKKLTSDITSSDEDDYEVCSKILNENTLR
DIERLTKDLHHQKTMDDFYRTFQSLPLQQRRELFSKLSSHQ

NT seq 8766 nt +upstreamnt +downstreamnt
atggttaatggcctcacaggagcattttcgcttgttctgttattccaaaactttgtagag
cccataaaatataacaacacgaattgctatgtacacatgcataataatgtcaatagaaac
aaccttatcaacacagaaacgagggaagtatatcagagtagaataaagggaaccaagaat
attcttcatgagagttacaggaacaggtatgtaccactcttcgtgtccaaaggaaccgaa
ctgctaagttcgttttttaagaataatagacggagaagtggagataactcgacgaatatt
tcgaagaacgggaagaagagttcgccgtcttcgttcaaagagaataactccccgcgtgcc
actatatgcagatcttcaagtgggagaaaatgggactcaagtaagggtaccgcggagcaa
aatgttgctcacgagaaagagtgcactgagcaaaagaggacgattgaggaattaacagat
gaattgcttagcagcctcagtagtcacaccgatgaaggctttatgagtgtcacatcgatt
gatcgcaacaacaggaactacataccaggaaaaactcaccacccaaggaatatgaacaat
gaaaatgggaagagcgacgacaatctttatacgaattcagctagttacagcccaggaaaa
atgtccgatgtattctcaaacggggattttgccaaggagagtgtcagaaggaaaaacaac
atagaagacaatctcacttttatgatggatctgattaaggaatcctctcccataccttac
aagggtggcgatgtgatcattcctcaggatcgttcgggagatgtactaatggatggtaga
cggctaaacaaagggaaggtaaaaaagaggaagaaacatctgaacagactttattacagc
tttaggggccataatgattttctctcccgaaaggagggtacccatgggggtgatgtgtgt
ctcggcccggtaagtaactctcctgtacagcagaaggaacgaaacccgttacagggaagg
gtgcaccgtaccaaggcgcagaattttcacgacggtgagaatgattttgcttctcctgcc
attcattcaagcgactccaacgatttcctaacatatgaagaaaaagagagggcaaaggaa
aaggcctatagggaatacacaaagtacatagaggagagaaggtacccatattttaatttc
gtaaaaaataagaatgggaagataataaaaaaattactaattgcaaataacggcatggca
gcgatgaaatgcattttatcaataaaggaatggctatttaaatctttttctgaggaaaac
ttaattaagatcatagtgctagccacagaagaagacatatcaagcaatgcaaaatacatt
tcgtttgccaacaaagttataaaggtacctcctggaaaaaactccaacaactatgccaat
gttcagctaattgtggatatagcaaaaaaggaacaagtggatgccgtttggccaggatgg
ggacactgttcagaaaatcccctactctccaccatgttggaaaaggagaacatcattttt
ataggaccaactggagatgtaatggaagccttaggagataaaatatctgctaatattctg
gcacaaagtgtaaatgtaccagttgtaaaatggagtggagacagcatacgagttgataat
tttgataaaaaaattagtgaagatatatacaataaatctaccatacattccttagatgcc
tgtataaaggagtgccaacggattggataccctgttatgataaaagcatcacaaggagga
ggggggaaaggtattcggaaagtggagaacgaagaagaaataaagaaagcctacacacaa
gtgcaaatggaattacccaactcgcctatctttctaatgaaagtctgtagcaacgttaga
cacatcgaaatacaagttgttggggatatgtatggtaatgtatgctcccttagtggaaga
gactgcacgacccaaaggaggttccaaaaaatttttgaagaagggcccccctcagttgta
cctccgaatattttccgtgaaatggaaaaggcatccatacgtctaacaaaaatgataaaa
tatagaggtgcgggaactattgagtatttatatgaccaggagaagcagacttattttttt
ctcgaattaaatcctcgactgcaggtggaacaccccgtgtcggagggcatcaccaacacg
aatcttatttcgatacagctacaggtggccatgggaattcccctccagaatatagatgac
attaggaggttgtaccgaataggggaagggcacggggacgcgagttttcgttcgccgata
ggggcctttcacaggttaggttccccatgtgactacacccctcctccaaatggtacgagc
gaaagcagcggtggtgctagtattgactgcgatgatggtagtaagaatggaggagaccaa
actaatgaattctcccccgcccgcgcggaacagatggatccattcgacttctataataac
aggccacacgtgagcaaccacgtgattgccgccagaatcactgcagaaaatagcaacgac
agttttaagcccacttcgggaaaggtaaaaagaatccatttccaaaattcgaacgacgtg
tggggatacttctcaatcaatgatggatccgtgcatgaattttctgattcacaaattggg
cacatttttgcaaaaggagaaacgagagaagtagctagaaaaaatttaatcctcgcatta
aggaaattaaacatagacggagaaataaagacaggcacaaaatatttagcaaaaattttg
gaatgcaaaccatttattgaaaataacataacgacaaattggttggatacaattattgag
aaaaaaaaatatatatattacagcgcagtacatataataattttgtgtgccacgattttt
aaactactcattcattttatcaaggaaaaagaagttattgaagatgcgctcaatagagaa
gacattggaattaagccacaggaagatgccttcactaatttaaagagagaagtaaaaaat
gcgtacgtgtttgatatcgtatttgaaaatgtgaggtacaattttaagggctataacaca
ggggagaatctttatactctaaaaattaatggacaagaaatcgaagttttagcagattat
gataaaaagaacaataaaatatttgcgagctttttcaatcacacttatttgtatacatgt
ttagaagacagcttaggaatccacatgcatctggataaggacagtatttttatccccaag
attagtaacccatttcatttggtgtcgaatacgaatgggaaaattgtaaaatatttgata
aaggatggagagaagatagagaagaatgaagactatatagaagtcgaggccatgaaaatg
ataatgacatttaagtctacagagaagggtatactcaggcacaagatgtcggagggtacc
attgtaaaaataggggatctcctgggagtgattgaggaaaactctcttgatagtaacact
cagcggggagagaaaaacgaaattaaaaccttcactggacatttggacttatcgaataag
tatgcatacgagttagaggaagcaagtcgactgtcatatcccattaagggggaaaatgtt
atgctcggttctgtccccacgtatgagtctacggaaggtgtctggcccattagtgatcaa
aaaatgggaagaggtcatttgtataagggaactgcaaattgtgacgatgaagggacactg
agagttgtgccaaaccatgcgtcaaatgaaatgcatcgtctgagtgaaaatgctgctggg
acacaacacggtatggatgccaccaagtcagaggatacctccttcttctcctccttcgaa
caagacgaagtatcatccaaggaaggaatcacaaagaatcggctattcctaaagcagagg
aaaaatatattccgcttatttgcaagcaagaaaaccagtgataagaaggaacataccgca
gcgagttacgtgaacgagaaatttaattccttcaaggagtacctgactagtttgagttcg
tccgacgaaaggtcggcggcacccaccagtgtcagcacgagcgtcaaggtggaggcagat
gtggacgaatctgcgcagatgggagtggacgtagccgcggagtcgaacaaatcgtactcc
aattctgaatccagggagtgtgcgaatgagtcgtccagtgcacacacggtgaatgatgag
tcgggaagtgctcaccaggggaaaaactctactggccttaactcaacctgcgagaattct
tcaactagcgaaaggaggaaccgtaacgaaaattcgtcgagcgaagttgtgtccacgagg
aatgcctccaatgagaagacgtccaacgagggtacgctcaattggggcacggaaaataag
gaggcatcgaaaacttcatcaaaaagttcatcaaaaagttcatcaaaaagtgcatcaaaa
agtgcatcggaaggaactttcaaatgcacctccaacagtcgcacacaagtggggggggat
acgccgggggtggattctccaggtggtcacccgtccaccgctgaagaacccagaaaggaa
caattccttttagacatcccgaatatgaagagagtagaatatttactaaaaggatatgag
caggattacgaagaatgcttcaatcaattagtgaaaaataaacgaaacttcatccctaac
attatttacattttaaaaaagtttatagagtacaattcactatttgctgaagaagaaaac
atcacgcaggtagaagtttacgatattttgcacaccaagtttaggaacgagaaaaaaaaa
aaatatgaaattgcccatgcatatacctataactatttaagcataaaatttgttttatta
gttttaaaatacttactagacagtgggttatcttcactcagtgaagtgccaaatgacctt
ctggataaactaaaagtgataacatcctttagagggaaattatttggcaacataattcta
ctgacgagggcgatagtacacatggcggaacgtatgcgcttggttgatttggtaaaaggt
gcattaaacgataggagtcacctttctggtgataaaattagccaactggaggaacacata
aagataaagcagagcatcattacacggtcaagattgggacaattttcaactgatacattt
acgccctcttctactttgatcagctatagaaactattgcgaacgtgtagtgaatacattt
ttggggagtccttcagacgtgcatatgttccttccatccctttttaccacagaaaataag
agcactcttctagaaatatacgttcagaatttgtataaacactttgatatcaaaacggaa
ctagtgcgtgatgattgccttaaattttttataaacaattcggaagaagaaaatttactc
atcctaaatgagaaaggtactgtatatgtggatgaatttatggacaaagggggaatgaat
cctaccgatggacgtataaagagcattcatattattaacagaaatgaacatttccctaat
gactatgaaggaagtgtagaacatataaaaaatatgtgtaagcatttatacatttatcac
tattttggggagaggtacggggatgtttacgagtggggtggagagggatacagcggggag
gagatccactcagggcgaaggacaaatctgctaccctaccaaagatatattttttccttt
gaaaagaactgtcaaaattatgacctagaaagtgtagatgagaaaatatttaaaggtacc
aaagtattcctcgggatgtacaaaaagaataaaaaaatccagtcgctatttgcagagagg
gtgatccatgtgtgtaatcttccaaagggtgaagtgtctgtactgagggaaactccacca
aaaggggagaatatcatggcaagacaggacttatcccatgtgatggagaaggagtggttc
caagacgcactcacagaagaatttaaagaagcggtcaatgatataaaaatagctagactg
aacccgaaagtgcaggacgcaaggctcagcagctacataacttaccatatagtactagat
gaagttaaagacaatgacgcagacgaattaaatataattgtagaggcgttgaagaacttc
ctcaataggcataacgagtttcttctagaaaactacgtgaacgatgtatatgcatgtgtt
tacagaaagggaggagaatctgccaaggggagactcaaattggaaccaaaaaaaatacta
agattgcacgtgctgtttgatggagaaaataatgtaatcgaggaagttggaagtgtaccc
atctttgacgttgacgcgttgtacttaaaaagaaaaagggctagagatatagatacgcta
tatgcctacgattttgtgaaggctataaatatttccctaaacaggatgaataacggagga
tccaaggatctgttcacatatgtgaatagcgtaaaggagtttaagctcgacttggaggca
ctacatggagtggaagattccaaggcggagggtaacatagcgaagcaatccatgtgtcat
acgggtgggttgtttcctcggcatgatggcctcagcgaagacgaagtaaagataagaaac
gcgctgtatctgtcagacaagctaaacgtaggccaaaacaaactgagcgtcattggtctg
ttgatgaacgtgaagacaatcgaatacaaagaaggcagagatgtcatttttatcataaat
gatataactacccatggtggctcattcagtgtagtggaagatcagttattttatgccata
tctagctacgcgagggagaagaaaattccgcgcatttatatatcgtgcaattcaggtgca
agaattgggctgtacaattttttgatggataaaattcaagtcagttggaaagacgaagaa
aagaaggaactggggtatgattatatttatataacagaagaggtcaaaaataaaatatcc
aaggaagacataatatttttaaaggaagttattaaaaatggggagaaaagatacataatt
gaaggtatagtaggaaacttaaataaccatattggagtggaaaatttaagggggagtggt
cttatcgctggtgaaacatccaaagcatatgatgaaatttttaccctatcatatgttacc
ggaagaagtgttggcatcggtgcttaccttgttaggctcgggaaaagaaccatccagaag
aaaggctcttcccttttactaacagggtttaatgccctaaataaaatattaggagaaaag
gtctatgtcagcaatgagcaattgggaggggtaaaaattatgatgagaaatggcatatct
caactagaagctcacaatgatcaggatggtgtggacaaaattttcaagtggctatcctat
gtacccaaaacgagtgaccattattatgatgttattgaggaggtgcgccagaagacaagt
ggaaatagctactatgagcagggtaaggtagagagcgcagaaagggaagtaaagaaactt
ttcgaggaggaagagaaacccacatcggagaaggaacctccaaaagtgtacttccaaaga
attaacgacatagacatggataacatacaaaacgcagatgtaatagaacttataaaggga
acagacacgaagcagggattcttagacaaaaatagctatttcgaatacatgaatgaatgg
ggaaaagggataataacggggaggggaaaattgggttccatcccggtgggaattatagct
gttaacagaaatttagtaacgcaagatgttccgtgcgatccagcattgaagaccaaagca
gtgagatcaacacaagcaccatgtgtttttttcccggacaattcatataaaactgctcag
tctattgaagattttaataaagaaaatttacccctatttgtttttgccaattggagaggg
ttttcaggtggtacaatggatatgtttaacagtattttaaaattcggatcaatgattgtt
aatcagttggttaattacaagcaccccgtttttgtgtacatcccaatttggggagagctg
agaggtggatcatgggttgttgtagacgaaacgttgaatagccaaatcatcgagatgtat
gcagatacgaacagtaaaggaggaattttggagccacccggaattgttgaggtgaagttt
aggttaccagaaataaggaagctgatgcacggtattgactcgtctataattactctggac
aagcggctgtccgaagcgcaggaggatggcgtgtctaaaataaaacaagaaatagaggac
aaagaaaaggagctattgccattttatttacaagtgtgccacagatatgcagatcttcac
gatgtgtcgaaatgcatgaagtccaagggagtgattaggaaaatcgttccttgggagaaa
gcccgctccttcttttactatcgcctcgtgcggcgcttgttaatgagcacgttgagcaga
aaatacggaacttctttgacccaaagtgaagaattcaaaaagctcaccagtgacatcacc
tcctccgacgaggacgactacgaagtgtgcagcaaaattttgaatgaaaatacgctgagg
gatatagagcgactaacgaaggatctgcaccatcagaaaacgatggacgacttttacagg
acctttcaaagtttgcccctacaacagagaagggaactctttagtaagctgagttcacat
cagtag

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   GENEDB (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (36)   

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