KEGG   Polynucleobacter necessarius: Pnec_0177
Entry
Pnec_0177         CDS       T00683                                 
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
pne  Polynucleobacter necessarius
Pathway
pne00300  Lysine biosynthesis
pne00550  Peptidoglycan biosynthesis
pne01100  Metabolic pathways
pne01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:pne00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    Pnec_0177
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Pnec_0177
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Pnec_0177
Enzymes [BR:pne01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     Pnec_0177
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: ACB43482
UniProt: B1XT05
Position
156507..157955
AA seq 482 aa
MSIMTTLAQAQAMLPGSTLVNVLVEAAQQLTLSRVGTDSRQIDRNELFVALVGERFDAHD
FLSDAAKAGTGAALISSQDKCPADLPAICVSNTRVGLGNLAKAWRANHPIPLALVTGSNG
KTTVKEMIASIFKAAVGEQHTLVTKGNLNNDIGLPLTLLKLRSTDRLAVVELGMNHPGET
AQLAVIAQANIALINNAQREHQEFMATVAAVAEEHSDAIRTLPSDGVAIFPADSEFAGVW
RQAAAGRKVIDFVLSSAQTKASAAVTGCLLSNGLVQIKSEQGTIEVQLNTLGSHNVRNAL
AASAVGIAAGVSLEKIKQGLESFSPVNGRMQAKAIDSSRTLIDDSYNANPDSVRVAIDAL
KQSGNLSWLILGDMGEVGNQGPEFHREVGAYAAEQGVAKLFALGEQCQFALQGFNEVNKG
GETTSHAKHFADMDSLIAQLRDALRSQSSGSNQHLNILVKGSRFMRMERVVQALLEEAKT
CS
NT seq 1449 nt   +upstreamnt  +downstreamnt
atgtccatcatgaccactcttgcacaagcacaagctatgctgcctggaagcactctagta
aatgttttagttgaggctgcgcagcaattgacgctttctcgtgtgggaactgatagtcgt
cagattgaccgcaatgaattatttgtggctttggttggtgagcgctttgatgctcatgat
tttttatcggatgcggcaaaagcgggtactggtgctgcacttataagtagtcaagataaa
tgccccgcagatttgcctgcaatttgtgtttcaaatactcgcgttggtttaggaaatctg
gcaaaagcctggcgtgccaatcatcccatacctttggcattggttaccggtagtaatggc
aagaccactgttaaagaaatgattgcctctatttttaaggctgcagtaggcgaacaacat
accttggtaacaaaaggtaatttgaataacgatattggcttgccgttaacactattgaag
ttacgttcaaccgatcgacttgcagtcgttgagctcggcatgaatcatcctggtgaaacg
gctcaattagctgtaatcgcacaagcaaatattgcattaattaataatgctcagcgcgaa
catcaagaatttatggccactgttgcagcagtagcggaagagcactctgacgccattcgt
actttgccaagtgatggagttgccatcttcccagcagactcggagtttgcaggtgtttgg
cgccaagcagccgcaggtcgaaaagtgattgattttgttctttcatctgcgcagaccaag
gcctcagctgcagtgactggatgcctcctgagcaatggactagtgcagattaaatctgaa
caaggcactatcgaagttcagttaaatactttgggtagtcacaatgttcgcaatgcctta
gcggcaagtgctgttggtatcgccgctggcgtcagcctcgaaaaaattaagcagggtctc
gaatccttctcgccagtcaatggaaggatgcaagctaaggcaattgattcaagccgaacc
ctcattgatgatagctataacgccaatcctgattctgtaagagtggccattgacgcttta
aaacaatcgggtaatttgtcatggttgattttgggtgatatgggtgaggttggcaatcaa
gggccagagtttcatcgggaagttggcgcttacgccgctgaacagggagttgccaaactc
tttgctttgggcgagcaatgccaattcgcccttcaaggatttaatgaagttaataaaggt
ggtgagactacctctcatgcaaaacattttgcggatatggacagcttgattgcgcaattg
agagatgcgctgcgctcacagtccagcggtagtaatcagcatttaaacattttggttaaa
ggttcacgatttatgcgcatggagcgtgtagtgcaagccttgttagaggaggctaaaaca
tgctcttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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