KEGG   Pongo abelii (Sumatran orangutan): 100172533Help
Entry
100172533         CDS       T01416                                 

Gene name
UGT1A3
Definition
(RefSeq) UDP-glucuronosyltransferase 1-3 precursor
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00040  Pentose and glucuronate interconversions
pon00053  Ascorbate and aldarate metabolism
pon00140  Steroid hormone biosynthesis
pon00830  Retinol metabolism
pon00860  Porphyrin and chlorophyll metabolism
pon00980  Metabolism of xenobiotics by cytochrome P450
pon00982  Drug metabolism - cytochrome P450
pon00983  Drug metabolism - other enzymes
pon01100  Metabolic pathways
pon05204  Chemical carcinogenesis
Module
pon_M00014  Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:pon00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    100172533 (UGT1A3)
   00053 Ascorbate and aldarate metabolism
    100172533 (UGT1A3)
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    100172533 (UGT1A3)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100172533 (UGT1A3)
   00860 Porphyrin and chlorophyll metabolism
    100172533 (UGT1A3)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100172533 (UGT1A3)
   00982 Drug metabolism - cytochrome P450
    100172533 (UGT1A3)
   00983 Drug metabolism - other enzymes
    100172533 (UGT1A3)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    100172533 (UGT1A3)
Enzymes [BR:pon01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     100172533 (UGT1A3)
Glycosyltransferases [BR:pon01003]
 Others
  Hydrophobic molecule
   100172533 (UGT1A3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: UDPGT Glyco_tran_28_C Glyco_transf_4
Motif
Other DBs
NCBI-GeneID: 100172533
NCBI-ProteinID: NP_001125615
Ensembl: ENSPPYG00000013293
UniProt: Q5RAZ6
Position
2B
AA seq 534 aa AA seqDB search
MATGLQVPLSWLATGLLLLLSVQSWAESGKVLVVPTDGSHWLSMREVVRELYARGHQAVV
LTPEVNMHIKEENFFTLTTYAIPWTQEEFDRVVLGHTQWFFETEHLLKRYSRSMAIMNNI
SLVLHRSCVELLHNEALIRHLNATSFDVVLTDPIYLCGVVLAKYLSIPTVFFLRNIPCDL
DFKGTQCPNPYSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ
REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGE
HGIVIFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
LLGHPMTRAFITHAGSHGIYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
SEDLENALKAVINDKSYKENIIRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCFGKKGRVKKAHKSKTH
NT seq 1605 nt NT seq  +upstreamnt  +downstreamnt
atggccacaggactccaggttcccctgtcgtggctggccacaggactgctgctcctcctc
agtgtccagtcctgggctgagagtggaaaggtgctggtggtgcccactgatggcagccac
tggctcagcatgcgggaggtcgtgcgggagctctatgccagaggccaccaggcggtggtc
ctcaccccggaggtgaatatgcacatcaaagaagagaactttttcacactgacaacctat
gccattccatggacccaggaggaatttgatcgcgttgtgctgggccacactcaatggttc
tttgaaacagaacatcttctgaagagatattctagaagtatggcaattatgaacaatata
tctttggtccttcataggtcttgtgtggagctactgcataatgaggccctgatcaggcac
ctgaatgctacttcctttgacgtagttttaacagaccccatttacctctgcggggtggtg
ctggctaagtacctgtcgattcctactgtgttttttttgaggaacattccatgtgactta
gactttaagggcacacagtgtccaaatccttactcctatattcctaagttactaacgacc
aattcagaccacatgacattcctgcaaagggtcaagaacatgctctaccctctggccctg
tcctacctttgccatgctgtttctgctccttatgcaagccttgcctctgagctttttcag
agagaggtgtcagtggtggatcttgtcagccatgcatctgtgtggctgttccgaggggac
tttgtgatggactaccccaggccaatcatgcccaacatggtcttcattgggggcatcaac
tgtgccaacaggaagccactatctcaggaatttgaagcctacattaatgcttctggagaa
catggaattgtgattttctctttgggatcaatggtctcagaaattccagagaagaaagcc
atggcaattgctgatgctttgggcaaaatccctcagacagtcctgtggcggtacactgga
acccgaccatcgaatcttgcgaacaacacgatacttgttaagtggctaccccaaaacgat
ctgcttggtcacccgatgacccgtgcctttatcacccatgctggttcccatggtatttat
gaaagcatatgcaatggcgttcccatggtgatgatgcccttgtttggtgatcagatggac
aatgcaaagcgcatggagactaagggagctggagtgaccctgaatgttctggaaatgact
tctgaagatttagaaaatgctctaaaagcagtcatcaatgacaaaagctacaaggaaaac
atcatacgcctctccagccttcacaaggaccgcccggtggagccgctggacctggctgtg
ttctgggtggagtttgtgatgaggcacaagggcgcgccacacctgcgccctgcagcccac
gacctcacctggtaccagtaccattccttggacgtgatcggtttcctcctggccgttgtg
ctgacagtggccttcatcacctttaaatgttgtgcttatggctaccggaaatgcttcggg
aaaaaagggcgagttaagaaagcccacaaatccaagacccattga

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