KEGG   Pongo abelii (Sumatran orangutan): 100174304Help
Entry
100174304         CDS       T01416                                 

Gene name
PRKAA1
Definition
protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31)
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:pon00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    100174304 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    100174304 (PRKAA1)
   04152 AMPK signaling pathway
    100174304 (PRKAA1)
   04150 mTOR signaling pathway
    100174304 (PRKAA1)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    100174304 (PRKAA1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100174304 (PRKAA1)
   04920 Adipocytokine signaling pathway
    100174304 (PRKAA1)
   04921 Oxytocin signaling pathway
    100174304 (PRKAA1)
  Environmental adaptation
   04710 Circadian rhythm
    100174304 (PRKAA1)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100174304 (PRKAA1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100174304 (PRKAA1)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100174304 (PRKAA1)
Protein kinases [BR:pon01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   100174304 (PRKAA1)
Mitochondrial biogenesis [BR:pon03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    100174304 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    100174304 (PRKAA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
5
AA seq 550 aa AA seqDB search
MATAEKQKHDGRVRIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVV
GKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRR
LFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPN
YAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLN
PSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCE
KFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTR
PHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIK
QLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTA
TPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEM
CANLIKILAQ
NT seq 1653 nt NT seq  +upstreamnt  +downstreamnt
atggcgacagccgagaagcagaaacacgacgggcgggtgaggatcggccactacatcctg
ggtgacacgctgggggtcggcaccttcggcaaagtgaaggttggcaaacatgaattgact
gggcataaagtagctgtgaagatactcaatcgacagaagattcggagccttgatgtggta
ggaaaaatccgcagagaaattcagaacctcaagcttttcaggcatcctcatataattaaa
ctgtaccaagtcatcagtacaccatctgatattttcatggtgatggaatatgtctcagga
ggagagctatttgattatatctgtaagaatggaaggctggatgagaaagaaagtcggcgt
ctgttccaacagatcctttctggtgtggattattgtcacaggcatatggtggtccataga
gatttgaaacctgaaaatgtcctgcttgatgcacacatgaatgcaaagatagctgatttt
ggtctttcaaacatgatgtcagatggtgaatttttaagaacaagttgtggctcacccaac
tatgctgcaccagaagtaatttcaggaagattgtatgcaggcccagaggtagatatatgg
agcagtggggttattctctatgctttattatgtggaacccttccatttgatgatgaccat
gtgccaactctttttaagaagatatgtgatgggatcttctatacccctcaatatttaaat
ccttctgtgattagccttttgaaacatatgctgcaggtggatcccatgaagagggccaca
atcaaagatatcagggaacatgaatggtttaaacaggaccttccaaagtatctctttcct
gaggatccatcatatagttcaaccatgattgacgatgaagccttaaaagaagtatgtgaa
aagtttgagtgctcagaagaggaagttctcagctgtctttataacagaaatcaccaggat
cctttggcagttgcctaccatctcataatagataataggagaataatgaatgaagccaaa
gatttctatttggcgacaagcccacctgattcttttcttgatgatcatcacctgactcgg
ccccatcctgaaagagtaccattcttggttgctgaaacaccaagggcacgccataccctt
gatgaattaaatccacagaaatccaaacaccaaggtgtaaggaaagcaaaatggcattta
ggaattagaagtcaaagtcgaccaaatgatattatggcagaagtatgtagagcaattaaa
caattggattatgaatggaaggttgtaaacccatattatttgcgtgtacgaaggaagaat
cctgtgacaagcacttactccaaaatgagtctacagttataccaagtggatagtagaact
tatctactggatttccgtagtattgatgatgaaattacagaagccaaatcagggactgct
actccacagagatcgggatcagttagcaactatcgatcttgccaaaggagtgattcagat
gctgaggctcaaggaaaatcctcagaagtttctcttacctcatctgtgacctcacttgac
tcttctcctgttgacctaactccaagacctggaagtcacacaatagaattttttgagatg
tgtgcaaatctaattaaaattcttgcacaataa

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