KEGG   Pongo abelii (Sumatran orangutan): 100174482Help
Entry
100174482         CDS       T01416                                 

Gene name
MAPK10
Definition
mitogen-activated protein kinase 10 (EC:2.7.11.24)
Orthology
K04440  
c-Jun N-terminal kinase [EC:2.7.11.24]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
FoxO signaling pathway
Protein processing in endoplasmic reticulum
Wnt signaling pathway
Osteoclast differentiation
Focal adhesion
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Adipocytokine signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Salmonella infection
Pertussis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Hepatitis B
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Colorectal cancer
Pancreatic cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100174482 (MAPK10)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100174482 (MAPK10)
   04010 MAPK signaling pathway
    100174482 (MAPK10)
   04012 ErbB signaling pathway
    100174482 (MAPK10)
   04310 Wnt signaling pathway
    100174482 (MAPK10)
   04668 TNF signaling pathway
    100174482 (MAPK10)
   04068 FoxO signaling pathway
    100174482 (MAPK10)
 Cellular Processes
  Cell communication
   04510 Focal adhesion
    100174482 (MAPK10)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    100174482 (MAPK10)
   04621 NOD-like receptor signaling pathway
    100174482 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    100174482 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    100174482 (MAPK10)
  Endocrine system
   04910 Insulin signaling pathway
    100174482 (MAPK10)
   04920 Adipocytokine signaling pathway
    100174482 (MAPK10)
   04912 GnRH signaling pathway
    100174482 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    100174482 (MAPK10)
   04917 Prolactin signaling pathway
    100174482 (MAPK10)
  Nervous system
   04728 Dopaminergic synapse
    100174482 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    100174482 (MAPK10)
   04722 Neurotrophin signaling pathway
    100174482 (MAPK10)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100174482 (MAPK10)
  Development
   04380 Osteoclast differentiation
    100174482 (MAPK10)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100174482 (MAPK10)
   05210 Colorectal cancer
    100174482 (MAPK10)
   05212 Pancreatic cancer
    100174482 (MAPK10)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100174482 (MAPK10)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100174482 (MAPK10)
  Infectious diseases
   05132 Salmonella infection
    100174482 (MAPK10)
   05133 Pertussis
    100174482 (MAPK10)
   05152 Tuberculosis
    100174482 (MAPK10)
   05164 Influenza A
    100174482 (MAPK10)
   05161 Hepatitis B
    100174482 (MAPK10)
   05160 Hepatitis C
    100174482 (MAPK10)
   05168 Herpes simplex infection
    100174482 (MAPK10)
   05169 Epstein-Barr virus infection
    100174482 (MAPK10)
   05145 Toxoplasmosis
    100174482 (MAPK10)
   05142 Chagas disease (American trypanosomiasis)
    100174482 (MAPK10)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100174482 (MAPK10)
Protein kinases [BR:pon01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [Table]
   100174482 (MAPK10)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
4
AA seq 384 aa AA seqDB search
MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRP
FQHQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEGFQDVYLVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSK
MLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDEQLDEREHTIDEWKELIYKEV
MNSEEKTKNGVVKGQPSPSAQVQQ
NT seq 1155 nt NT seq  +upstreamnt  +downstreamnt
atgagcaaaagcaaagttgacaaccagttctacagtgtggaagtgggagactcaaccttc
acagttctcaagcgctaccagaatctaaagcctattggctctggggctcagggcatagtt
tgtgccgcgtatgatgctgtccttgacagaaatgtggccattaagaagctcagcagaccc
tttcagcaccaaacacatgccaagagagcgtaccgggagctggtcctcatgaagtgtgtg
aaccataaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggagggg
ttccaagatgtttacttggtaatggaactgatggatgccaacttatgtcaagtgattcag
atggaattagaccacgagcgaatgtcttacctgctgtaccaaatgttgtgtggcattaag
cacctccattctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaag
tctgattgcacattgaaaatcctggactttggactggccaggacagcaggcacaagcttc
atgatgactccatatgtggtgacacgttattacagagcccctgaggtcatcctggggatg
ggctacaaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgc
cacaaaatcctctttccaggaagggactatattgaccagtggaataaggtaattgaacaa
ctaggaacaccatgtccagaattcatgaagaaattgcaacccacagtaagaaactatgtg
gagaatcggcccaagtatgcaggactcaccttccccaagctcttcccagattccctcttc
ccagcggactccgagcacaataaactcaaagccagccaagccagggacttgttgtcaaag
atgctagtgattgacccagcaaaaagaatatcagtggacgatgccttacagcatccctac
atcaacgtctggtatgacccagccgaagtggaggcgcctccacctcagatatatgacgag
cagttggatgaaagagaacacacaatcgatgaatggaaagaacttatctacaaggaagta
atgaactcagaagaaaagactaaaaatggcgtagtaaaaggacagccttctccttcagca
caggtgcagcagtga

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