KEGG   Pongo abelii (Sumatran orangutan): 100174748Help
Entry
100174748         CDS       T01416                                 

Gene name
PRKACB
Definition
protein kinase, cAMP-dependent, catalytic, beta (EC:2.7.11.1)
Orthology
K04345  
protein kinase A [EC:2.7.11.11]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
MAPK signaling pathway
Ras signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Apoptosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Hedgehog signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Olfactory transduction
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Bile secretion
Parkinson's disease
Prion diseases
Cocaine addiction
Amphetamine addiction
Morphine addiction
Amoebiasis
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pon00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100174748 (PRKACB)
   04010 MAPK signaling pathway
    100174748 (PRKACB)
   04310 Wnt signaling pathway
    100174748 (PRKACB)
   04340 Hedgehog signaling pathway
    100174748 (PRKACB)
   04020 Calcium signaling pathway
    100174748 (PRKACB)
   04024 cAMP signaling pathway
    100174748 (PRKACB)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    100174748 (PRKACB)
   04210 Apoptosis
    100174748 (PRKACB)
  Cellular commiunity
   04540 Gap junction
    100174748 (PRKACB)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100174748 (PRKACB)
   04062 Chemokine signaling pathway
    100174748 (PRKACB)
  Endocrine system
   04911 Insulin secretion
    100174748 (PRKACB)
   04910 Insulin signaling pathway
    100174748 (PRKACB)
   04912 GnRH signaling pathway
    100174748 (PRKACB)
   04913 Ovarian Steroidogenesis
    100174748 (PRKACB)
   04915 Estrogen signaling pathway
    100174748 (PRKACB)
   04914 Progesterone-mediated oocyte maturation
    100174748 (PRKACB)
   04921 Oxytocin signaling pathway
    100174748 (PRKACB)
   04918 Thyroid hormone synthesis
    100174748 (PRKACB)
   04919 Thyroid hormone signaling pathway
    100174748 (PRKACB)
   04916 Melanogenesis
    100174748 (PRKACB)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100174748 (PRKACB)
   04270 Vascular smooth muscle contraction
    100174748 (PRKACB)
  Digestive system
   04970 Salivary secretion
    100174748 (PRKACB)
   04971 Gastric acid secretion
    100174748 (PRKACB)
   04976 Bile secretion
    100174748 (PRKACB)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    100174748 (PRKACB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100174748 (PRKACB)
  Nervous system
   04724 Glutamatergic synapse
    100174748 (PRKACB)
   04727 GABAergic synapse
    100174748 (PRKACB)
   04725 Cholinergic synapse
    100174748 (PRKACB)
   04728 Dopaminergic synapse
    100174748 (PRKACB)
   04726 Serotonergic synapse
    100174748 (PRKACB)
   04720 Long-term potentiation
    100174748 (PRKACB)
   04723 Retrograde endocannabinoid signaling
    100174748 (PRKACB)
  Sensory system
   04740 Olfactory transduction
    100174748 (PRKACB)
   04742 Taste transduction
    100174748 (PRKACB)
   04750 Inflammatory mediator regulation of TRP channels
    100174748 (PRKACB)
  Environmental adaptation
   04713 Circadian entrainment
    100174748 (PRKACB)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100174748 (PRKACB)
   05205 Proteoglycans in cancer
    100174748 (PRKACB)
   05203 Viral carcinogenesis
    100174748 (PRKACB)
  Neurodegenerative diseases
   05012 Parkinson's disease
    100174748 (PRKACB)
   05020 Prion diseases
    100174748 (PRKACB)
  Substance dependence
   05030 Cocaine addiction
    100174748 (PRKACB)
   05031 Amphetamine addiction
    100174748 (PRKACB)
   05032 Morphine addiction
    100174748 (PRKACB)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    100174748 (PRKACB)
  Infectious diseases
   05166 HTLV-I infection
    100174748 (PRKACB)
   05169 Epstein-Barr virus infection
    100174748 (PRKACB)
   05146 Amoebiasis
    100174748 (PRKACB)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100174748 (PRKACB)
Protein kinases [BR:pon01001]
 Serine/threonine protein kinases: AGC group
  PKA family
   100174748 (PRKACB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
1
AA seq 354 aa AA seqDB search
MSARKSSDASACSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGR
VMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNL
YMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDH
QGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYP
PFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKW
FATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
NT seq 1065 nt NT seq  +upstreamnt  +downstreamnt
atgagtgcacgcaaatcatcagatgcatctgcttgctcctcttcagaaatatctgtgaaa
gagtttctagccaaagccaaagaagactttttgaaaaaatgggagaatccaactcagaat
aatgccggacttgaagattttgaaaggaaaaaaacccttggaacaggttcatttggaaga
gtcatgttggtaaaacacaaagccactgaacagtattatgccatgaagatcttagataag
cagaaggttgttaaactgaagcaaatagagcatactttgaatgagaaaagaatattacag
gcagtgaattttcctttccttgttcgactggagtatgcttttaaggataattctaattta
tacatggttatggaatatgtccctgggggtgaaatgttttcacatctaagacgaattgga
aggttcagtgagccccatgcaaggttctatgcagctcagatagtgctaacattcgagtac
ctccattcactagacctcatctacagagatctaaaacctgaaaatctcttaattgaccat
caaggctatatccaggtcacagactttgggtttgccaaaagagttaaaggcagaacttgg
acattatgtggaactccagagtatttggctccagaaataattctcagcaagggctacaat
aaggcagtggattggtgggcattaggagtgctaatctatgaaatggcagctggctatccc
ccattctttgcagaccaaccaattcagatttatgaaaagattgtttctggaaaggtccga
ttcccatcccacttcagttcagatctcaaggaccttctacggaacctgctgcaggtggat
ttgaccaagagatttggaaatctaaagaatggtgtcagtgatataaaaactcacaagtgg
tttgccacgacagattggattgctatttaccagaggaaggttgaagctccattcatacca
aagtttagaggctctggagataccagcaactttgatgactatgaagaagaagatatccgt
gtctctataacagaaaaatgtgcaaaagaatttggtgaattttaa

DBGET integrated database retrieval system