KEGG   Pongo abelii (Sumatran orangutan): 100433232Help
Entry
100433232         CDS       T01416                                 

Gene name
SPHK1
Definition
sphingosine kinase 1
Orthology
K04718  
sphingosine kinase [EC:2.7.1.91]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
Sphingolipid metabolism
Metabolic pathways
Calcium signaling pathway
VEGF signaling pathway
Fc gamma R-mediated phagocytosis
Tuberculosis
Module
Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:pon00001]
 Metabolism
  Lipid metabolism
   00600 Sphingolipid metabolism
    100433232 (SPHK1)
 Environmental Information Processing
  Signal transduction
   04370 VEGF signaling pathway
    100433232 (SPHK1)
   04020 Calcium signaling pathway
    100433232 (SPHK1)
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    100433232 (SPHK1)
 Human Diseases
  Infectious diseases
   05152 Tuberculosis
    100433232 (SPHK1)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphinganine kinase
     100433232 (SPHK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
17
AA seq 470 aa AA seqDB search
MSAQVLGFLRSWTPLPLAAPRDPAAAGNDAGAPTAKAPGGEGEPHSRPCDARLGSTDKEL
KAGAAATGSAPTAQGTPWQREPRVEVMDPAGGPRGVLPRPCRVLVLLNPRGGKGKALQLF
RSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMER
PDWETAIRKPLCSLPAGSGNALAASLNHYAGYEQVTSEDLLTNCTLLLCRRLLSPMNLLS
LHTASGLHLFSVLSLAWGFIADVDLESEKYRRLGEMLFTLGTFLRLAALRTYRGRLAYLP
VGGVGSKTPASPVVVEQGPVDAHLVPLEEPVPSHWTVVPDQDFVLVLALLHSHLGSEMFA
APMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDG
RGVFAVDGELMVSEAVQGQVHPNYFWMVSGCVEPPPSWKPQQTPPPEEPL
NT seq 1413 nt NT seq  +upstreamnt  +downstreamnt
atgtccgctcaagttctgggatttttacgcagctggactcccctccccctggcagccccg
agggatccagccgccgcagggaatgacgccggtgctcctacagccaaggctccgggcggg
gagggcgagccccacagccggccctgcgacgcccgcctgggcagcaccgataaggagctg
aaggcaggagccgccgccacgggcagcgcccccacagcgcaggggaccccctggcagcgg
gagccgcgggtcgaggttatggatccagcgggcggcccccggggcgtgctcccgcggccc
tgccgcgtgctggtgctgctgaacccgcgcggcggcaagggcaaggccctgcagctcttc
cggagtcacgtgcagccccttttggctgaggctgaaatctccttcacgctgatgctcact
gagcggcggaaccatgcgcgggagctggtgcggtcggaggagctgggccgctgggacgct
ctggtggtcatgtctggagacgggctgatgcacgaggtggtgaacgggctcatggagcgg
cctgactgggagaccgccatccggaagcccctgtgtagcctaccagcaggctctggcaac
gcgctggcagcttccttgaaccattatgctggctatgagcaggtcaccagtgaagacctc
ctgaccaactgcacgctgttgctgtgccgccggctactgtcgcccatgaacctgctgtct
ctgcacacggcttcggggctgcacctcttctctgtgctcagcctggcctggggcttcatt
gctgatgtggacctagagagtgagaagtatcggcgtctgggggagatgctcttcactctg
ggcaccttcctgcgtctggccgccctgcgcacctaccgcggccgactggcctacctccct
gtaggaggagtcggctccaagacacctgcctcccccgttgtggtcgagcagggccccgta
gatgcacaccttgtgccactggaggagccagtgccctctcactggacagtggtgcccgac
caggacttcgtgctagtcctggcgctgctgcactcgcacctgggcagtgagatgtttgct
gcacccatgggccgctgtgcagctggtgtcatgcatctgttctacgtgcgggcgggagtg
tctcgggccatgctgctgcgcctcttcctggccatggagaagggcaggcatatggagtat
gaatgcccctacttggtatacgtgcccgtggtcgccttccgcttagagcccaaggatggg
agaggtgtgtttgcagtggatggggaattgatggttagcgaggccgtgcagggccaggtg
cacccaaactacttctggatggtcagtggttgcgtggagcccccgcccagctggaagccc
cagcagacgccacctccagaagagcccttatga

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