KEGG   Pongo abelii (Sumatran orangutan): 100434331Help
Entry
100434331         CDS       T01416                                 

Gene name
SOS2
Definition
son of sevenless homolog 2 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100434331 (SOS2)
   04010 MAPK signaling pathway
    100434331 (SOS2)
   04012 ErbB signaling pathway
    100434331 (SOS2)
   04630 Jak-STAT signaling pathway
    100434331 (SOS2)
   04068 FoxO signaling pathway
    100434331 (SOS2)
   04151 PI3K-Akt signaling pathway
    100434331 (SOS2)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100434331 (SOS2)
  Cell communication
   04510 Focal adhesion
    100434331 (SOS2)
   04540 Gap junction
    100434331 (SOS2)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100434331 (SOS2)
   04660 T cell receptor signaling pathway
    100434331 (SOS2)
   04662 B cell receptor signaling pathway
    100434331 (SOS2)
   04664 Fc epsilon RI signaling pathway
    100434331 (SOS2)
   04062 Chemokine signaling pathway
    100434331 (SOS2)
  Endocrine system
   04910 Insulin signaling pathway
    100434331 (SOS2)
   04912 GnRH signaling pathway
    100434331 (SOS2)
   04915 Estrogen signaling pathway
    100434331 (SOS2)
   04917 Prolactin signaling pathway
    100434331 (SOS2)
  Nervous system
   04722 Neurotrophin signaling pathway
    100434331 (SOS2)
  Development
   04320 Dorso-ventral axis formation
    100434331 (SOS2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100434331 (SOS2)
   05206 MicroRNAs in cancer
    100434331 (SOS2)
   05205 Proteoglycans in cancer
    100434331 (SOS2)
   05214 Glioma
    100434331 (SOS2)
   05221 Acute myeloid leukemia
    100434331 (SOS2)
   05220 Chronic myeloid leukemia
    100434331 (SOS2)
   05211 Renal cell carcinoma
    100434331 (SOS2)
   05215 Prostate cancer
    100434331 (SOS2)
   05213 Endometrial cancer
    100434331 (SOS2)
   05223 Non-small cell lung cancer
    100434331 (SOS2)
  Substance dependence
   05034 Alcoholism
    100434331 (SOS2)
  Infectious diseases
   05160 Hepatitis C
    100434331 (SOS2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
14
AA seq 1332 aa AA seqDB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPYDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPEFHEHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYSHQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHGQTRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCEYKHAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLA
IEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIRRKKQAQANGISHNITFESPPPPIEWHISKPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSVFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKIKPRVPVPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDSDWLRDISTCPNSPS
TPPSTPSPRVPRRCYVLSSSQNNLAHPPAPPVPPRQNSSPHLPKLPPKTYKREFSHPPLY
RLPLLENAETPQ
NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt
atgcagcaggcgccgcagccttacgagttcttcagcgaggagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggaacaagtgcatcccactctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccagccaaggactgttcaagatgtagaggagcgagttcagaagacctttcctcac
ccaattgataaatgggccattgctgatgcacaatctgctatagaaaaacgaaaacgaaga
aatcctcttttactgcctgtggacaaaatccatccttcgttgaaggaagtgttagggtac
aaagtggactaccatgtatccctatatattgtggctgtactagagtatatctcagctgat
attttaaaattggctggtaattatgtttttaatatccggcattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcggataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttctctctgtgaagatgaacctagttcttctggtgaattaaactactat
gatcttgtcagaactgaaatcgcagaagaaagacagtatctacgggaattaaatatgatc
ataaaagtgtttcgagaagcctttctttctgataggaagctctttaaaccttatgatatc
gaaaagatttttagtaacatttcagatatacatgaattgactgtgaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttcaccagagtttcatgaacatttcaataaattgatggccagacctgcagttgctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgtctt
atgctggtgccagtgtaccactgttggcactactttgagttattaaagcaattgaaagca
tgtagtgaagaacaagaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagcatggaccgaatttacaagcagtattcacctagacgtcgacctggagat
cctgtttgccctttttatagtcatcaattaagaagcaaacacctggctatcaaaaaaatg
aatgaaattcagaaaaatatcgatggatgggaaggcaaagatattggacagtgttgtaat
gaattcattatggagggaccattgacaagaatcggtgccaaacatgaacggcatattttt
ctgtttgatggcttaatgatcagttgtaaacctaatcatggccagactcggcttccaggt
tacagtagtgcagaatacaggttaaaagaaaaatttgtcatgaggaaaatacaaatttgt
gataaagaagatacttgtgagtacaagcatgcatttgaattagtatccaaagatgagaac
agcataatatttgctgctaagtctgctgaagaaaaaaacaactggatggcagcccttatt
tctcttcattatcgtagtactctagatcgaatgttagattcagtattattgaaagaagaa
aatgagcaaccactgagattaccaagtcctgaagtatatcgttttgtagtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggcatccccattattaaa
ggaggaactgtagtgaaattaattgaaaggttaacataccatatgtatgcagatcccaat
tttgttcgtacttttcttaccacatatcgttcattttgtaaaccacaggaattgctgagc
ttactgattgaacggtttgaaattccagagccagaacctactgacgcagacaaattggca
atagagaaaggcgagcagccaatcagtgcagaccttaaaagatttcgcaaggaatacgtc
caaccagtacaacttaggatcttaaatgtatttcggcattgggttgaacatcatttttat
gactttgaaagagacttggaattgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaaaaaatgggtagagtcaatcgctaaaatcatcaggaggaagaagcaa
gctcaggcaaacggaataagccataatattacctttgaaagtccacctccaccaattgaa
tggcatatcagcaaaccaggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggagtctgatctctacaggaaagttcaaccgtct
gaacttgtagggagtgtgtggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacaaatctcaccctctggtttgaaaaatgcattgtggaagca
gaaaattttgaagaacgggtggcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggcgtattggagatagtcagtgcagtaaattcagtgtcg
gtatacagactagaccatacctttgaggcattgcaggaaagaaaaaggaaaattttggat
gaggctgtggaattaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc
aacccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagaccgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcagaatcagccttactgtttacgg
atagaaccagatatgaggagattctttgaaaaccttaaccccatgggaagtgcatctgaa
aaagagtttacagattatttgttcaacaagtcactagaaattgaacctcgaaactgcaaa
cagccacctcgatttcctaggaaatcaactttctccttaaaatctcctggaatacggcct
aacaccggccgacatggctctacctcaggtactttacgaggtcacccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaactgagctggaatcaacagtg
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtatttttagatgtggatctcaacagctcctgtggcagcaatagcgtctttgctcca
gtgcttttgccacattcaaagtctttctttagttcatgtggtagtttacataaactaagt
gaagagcccctgattcctcctcctcttcctcctcgaaaaaagtttgatcatgatgcttca
aattccaagggaaatatgaaatctgatgatgatcctcctgctattccaccaagacagcct
cctcctccaaagataaaacccagagttcctgttcctactggtgcatttgatgggcctctg
catagtccacctccgccaccaccaagagatcctcttcctgatacccctccaccggttccc
cttcggcctccagaacactttataaactgtccatttaatcttcagccacctccactgggg
catcttcacagagattcagactggcttagagacattagtacgtgtccaaattcgccaagc
actcctcctagcacaccctctccaagggtaccgcgtcgatgctatgtgctcagttctagt
cagaataatcttgctcatcctccagctccccctgttccaccaaggcagaattcaagccct
catctgccaaaactgccaccaaagacttacaaacgggagttttcgcaccccccattgtac
agactgcctttgctagaaaatgcagaaactccccaatga

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