KEGG   Pongo abelii (Sumatran orangutan): 100434502Help
Entry
100434502         CDS       T01416                                 

Gene name
PLCB1
Definition
phospholipase C, beta 1 (phosphoinositide-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:pon00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:pon04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:pon04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:pon04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:pon04070]
Cellular Processes; Cell communication; Gap junction [PATH:pon04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:pon04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:pon04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:pon04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:pon04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:pon04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:pon04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:pon04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:pon04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:pon04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:pon04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:pon04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:pon04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:pon04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:pon04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:pon04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:pon04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:pon04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:pon04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:pon04720]
Organismal Systems; Nervous system; Long-term depression [PATH:pon04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:pon04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:pon04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:pon04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:pon05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:pon05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:pon05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:pon05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:pon05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
20
AA seq 1214 aa AA seqDB search
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
KLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVELYNKMQLSRIYPKGT
RVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHF
DPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNA
VNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQ
PLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEA
DPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVL
TEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRR
RAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQE
QYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITE
AKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKL
QVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEE
LGGDIPGKEFDTPL
NT seq 3645 nt NT seq  +upstreamnt  +downstreamnt
atggccggggctcaacccggagtgcacgccttgcaactcaagcccgtgtgcgtgtccgac
agcctcaagaagggcaccaaattcgtcaagtgggatgatgactcaactattgttactcca
attattttgaggactgaccctcagggatttttcttttactggacagatcaaaacaaggag
acggagctactggatctcagccttgtcaaagatgccagatgtgggagacacgccaaagct
cccaaggaccctaaattacgtgaacttttggatgtggggaacatcgggcgcctggagcag
cgcatgatcacagtggtgtatgggcctgacctcgtgaacatctcccatttgaatctcgtg
gctttccaagaagaagtggccaaggaatggacaaatgaggttttcagtttggcaacaaac
ctgctggcccaaaacatgtccagggatgcatttctggaaaaagcctatactaaacttaag
ctgcaagtcactccagaagggcgtattcctctcaaaaacatatatcgcttgttttcagca
gaccggaagcgagttgaaactgctttagaggcttgtagtcttccatcttcaaggaatgat
tcaatacctcaagaagatttcactccagaagtgtacagagttttcctcaacaacctttgc
cctcgacctgaaattgataacatcttttcagaatttggtgcaaaaagcaaaccatatctt
accgttgatcagatgatggattttatcaaccttaagcagcgagatcctcggcttaatgaa
atactttatccacctctaaaacaagagcaagtccaagtattgattgagaagtatgaaccc
aacaatagcctcgccagaaaaggacaaatatcagtggatgggttcatgcgctatctgagt
ggagaagaaaacggagtcgtttcacctgagaaactggatttgaatgaagacatgtctcag
ccactttctcactatttcattaattcctcgcacaacacctacctcacagctggccaactg
gctggaaactcctctgttgagatgtatcgccaagtgctcctgtctggttgtcgctgtgtg
gagctggactgctggaagggacggactgcagaagaggaacctgtcatcacccatggcttc
accatgacaactgaaatatctttcaaggaagtgatagaagcaattgcggagtgtgcattt
aagacttcaccttttccaattctcctttcatttgagaaccatgtggattccccaaagcag
caagccaagatggcggagtactgccgactgatctttggggatgcccttctcatggagccc
ctggaaaaatatccactggaatctggagttcctcttccaagccctatggatttaatgtat
aaaattttggtgaaaaataagaagaaatcacataagtcatcagaaggaagcggcaaaaag
aagctctcagaacaagcctccaacacctacagtgactcctccagcgtgttcgagccctca
tccccaggagccggagaagctgatacggaaagtgacgacgacgatgatgatgatgactgt
aaaaaatcttcaatggatgaggggaccgctggaagtgaggctatggccacagaagaaatg
tctaacctggtgaactatattcagccagtcaagtttgagtcatttgaaatttcaaaaaaa
agaaataaaagttttgaaatgtcttccttcgtggaaaccaaaggacttgaacaactcacc
aagtctccggtggaattatataacaaaatgcagcttagcaggatatatccaaaaggaaca
cgtgtggattcatccaactatatgcctcagctcttctggaatgcaggttgtcagatggtg
gcacttaatttccagacaatggacctggctatgcaaataaatatggggatgtatgaatac
aacgggaagagtggctacagattgaagccagagttcatgaggaggcctgacaagcatttt
gatccatttactgaaggcatcgtagatgggatagtggcaaacactttgtctgttaagatt
atttcaggtcagtttctttctgataagaaagttgggacttacgtggaagtggatatgttt
ggtttgcctgtggatacaaggaggaaggcatttaagaccaaaacatcccaaggaaatgct
gtgaatcctgtctgggaagaagaacctattgtgttcaaaaaggtggttcttcctactctg
gcctgtttgagaatagcagtttatgaagaaggaggtaaattcattggccaccgtatcttg
ccagtgcaagccattcggccagggtatcactatatctgtctaaggaatgaaaggaaccag
cctctgacgctgcctgctgtctttgtctacatagaagtgaaagactatgtgccagacaca
tatgcagatgtcattgaagctttatcaaacccaatccgatatgtgaacctgatggaacag
agagctaagcaattggctgctttgacactggaagatgaagaagaagtaaagaaagaggct
gatcctggagaaacaccatcagaggctccaagtgaagcgagaacgactccagcagaaaac
ggggtgaatcacaccacaaccctgacacccaaaccaccctcccaggctctccacagccag
ccagctccaggttctgtaaaggcacctgccaaaacagaagatcttattcagagtgtctta
acagaagtggaagcacagaccatcgaagaactaaagcaacagaaatcgtttgtgaaactt
caaaagaaacactacaaagaaatgaaagacctggttaagagacaccacaagaaaaccact
gaccttatcaaagaacacactaccaagtataatgaaattcagaatgactacttgagaagg
agagcagccttggaaaagtctgccaaaaaggacagtaagaaaaaatcggaacccagcagc
cctgatcatggttcatcaacgattgagcaagacctcgctgccctggatgctgaaatgacc
caaaagttaatagacttgaaggacaaacaacagcagcagctgcttaatcttcggcaagaa
cagtattatagtgaaaaataccagaagcgagaacatattaaactgcttattcaaaagttg
acggatgtcgcagaagagtgtcagaacaatcagttaaagaagctcaaagaaatctgtgag
aaagaaaagaaagaattaaagaagaaaatggataaaaagaggcaggagaagataacagaa
gctaaatccaaagacaaaagtcagatggaagaggagaagacagagatgatccggtcatat
atccaggaagtggtgcagtatatcaagaggctagaagaagcgcaaagtaaacgacaagaa
aaactcgtagagaaacacaaggaaatacgtcagcagatcctggatgaaaagcccaagctg
caggtggagctggagcaagaataccaagacaaattcaaaagactgcccctcgagattttg
gaattcgtgcaggaagccatgaaaggaaagatcagtgaagacagcaatcacggttctgcc
cctctctccctgtcctcagaccctggaaaagtgaaccacaagactccctccagtgaggaa
ctgggaggagacatcccaggaaaagaatttgatactcctctgtga

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