KEGG   Pongo abelii (Sumatran orangutan): 100438951Help
Entry
100438951         CDS       T01416                                 

Gene name
ARHGEF1
Definition
Rho guanine nucleotide exchange factor (GEF) 1
Orthology
K12330  
Rho guanine nucleotide exchange factor 1
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
Vascular smooth muscle contraction
Platelet activation
Regulation of actin cytoskeleton
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100438951 (ARHGEF1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100438951 (ARHGEF1)
  Circulatory system
   04270 Vascular smooth muscle contraction
    100438951 (ARHGEF1)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    100438951 (ARHGEF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
19
AA seq 710 aa AA seqDB search
AKKAFLDFYHSFLEKTAVLRVPVPPNVAFELDRTRADLISEDVQRRFVQEVVQSQQTAVG
RQLEDFRSKRLMGMTPWEQELAQLEAWVGRDRASYEARERHVAERLLMHLEEMQHTISTD
EEKREEGAPCHAEKPGATDRKGGLGMPSRDRNVGAPGQDSPGVSLHPLSLDSTDREPGES
FLGQGSPAHEVMPPSLHPPQRASCFGGPAELLVTEAAHVRMLRVLHDLFFQPMAEGLFFP
LEELQNIFPSLDELIEVHSLFLDRLMKRRQESGYLIEEIGDVLLARFDGTEGSWFQKISS
RFCSRQSFALEQLKAKQRKDPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQ
SIGQNTEEPKEREKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDP
MLSEFKNLDITKKKLVHEGPLTWRVTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRT
LTPTPDGKTMLRPVLRLTSAMTREVATDHKAFYVLFTWDQEAQIYELVAQTVSERKNWCA
LITETAGSLKVPAPASRPKPRPSPSSTREPLXXXXXXXXXRTERILSDLLPFCRPGPEGQ
LAATALRKVLSLKQLLFPAEEDNGAGPPRDGDGVPGGGPLSPARTQEIQENLLSLEETMK
QLEELEEEFCRLRPLLSQLGGTLSPSLPISPLLLHPPRPFARRRGMGERT
NT seq 2133 nt NT seq  +upstreamnt  +downstreamnt
gccaagaaggccttcctggacttctaccacagcttcctggagaagacagcggttctgcgg
gtgccagtccctcccaacgtcgcctttgaacttgaccgcactagggctgacctcatctcc
gaagatgtccagcggcggttcgtgcaggaggtggtgcaaagccagcagacagccgtgggc
cggcagctggaagacttccgctccaagcggctcatgggcatgacgccctgggagcaggag
ctggcccagctggaggcttgggttgggcgggaccgagccagctacgaggcccgggagcgg
cacgtggcagagcggctgctcatgcacctggaggagatgcaacataccatctctaccgac
gaagaaaagagggaggaaggggctccttgtcatgctgagaagccaggtgctacagaccgg
aagggaggcctggggatgccctctcgggaccggaatgtcggggctcctgggcaggacagc
cctggagtctctctgcaccctctgtccctggacagcacagaccgggaaccaggtgagagt
ttcctgggccagggctcccctgcccatgaggtcatgccccctagtctgcaccctccccaa
cgtgcttcctgctttggtggccctgcagagttgttggtgacagaggcggcccatgtgcgc
atgctgcgggtgctgcacgacctcttcttccagcccatggcagaaggcctcttcttcccc
ttggaggagctgcagaacatcttccccagcctggacgagctcatcgaggtgcattccctg
ttcctcgatcgcctgatgaagcggaggcaggagagtggctacctcatcgaggagatcgga
gacgtgctgctggcccggtttgatggtactgagggctcctggttccagaaaatctcctcc
cgcttctgcagccgccagtcgtttgccttagagcagctcaaagccaagcaacgcaaggac
cctcggttctgtgccttcgtgcaggaagctgagagccgcccgcggtgccgccgcctgcag
ctgaaggacatgatccccacggagatgcagcggctgaccaagtaccccctgctcctgcag
agcatcgggcagaacacagaagagcccaaggaacgggagaaagtggagctggcagccgag
tgctgccgggaaattctacaccacgtcaaccaagccgtgcgtgacatggaggatctgctg
aggctcaaggactatcagcggcgcctggacttgtcccaccttcggcagagcagcgacccc
atgctgagcgagttcaagaacctggacatcaccaagaagaaattggtccacgagggccca
ctgacgtggcgggtgactaaggacaaggctgtggaggtgcatgtgctgctgctggacgac
ctgctgctgctgctccagcgccaggacgagcggctgctgctcaagtcccatagccggaca
ctgacgcccacgcccgacggcaagaccatgctgcggcccgtgctgcggctcacctcagcc
atgacccgcgaggtggccaccgatcacaaagccttctacgtccttttcacctgggaccag
gaggcccagatatacgagctggtggcacagactgtgtcggagcggaaaaactggtgtgcc
ctcatcactgagactgccggatccctgaaagtccctgcccctgcctctcgccctaagccc
cggcccagcccgagcagcacccgagaacccctcnnnnnnnnnnnnnnnnnnnnnnnnncc
cggacagagagaatcctcagtgacctcctgcccttctgcagaccaggccctgagggccag
ctcgctgccacggcccttcggaaagtgctgtccctgaagcagcttctgtttccggcggag
gaagacaatggggcggggcctcctcgagatggggatggggtcccagggggcggccccctg
agcccagcacggacccaagaaatccaggagaacctgctcagcttggaggagaccatgaag
cagctggaggagttggaggaggaattttgccgcctgagacccctcctgtctcagcttggg
gggactctctctccatctctccccatctcccctcttctcctacatcccccaaggcctttt
gcaagaagaagaggaatgggggagaggacgtga

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