KEGG T01416: 100442074

Pongo abelii (Sumatran orangutan): 100442074

Entry

100442074 CDS T01416

Gene name

ITGA8

Definition

integrin, alpha 8

Orthology

K06584

integrin alpha 8

Organism

pon Pongo abelii (Sumatran orangutan)

Pathway

pon04151	PI3K-Akt signaling pathway
pon04510	Focal adhesion
pon04512	ECM-receptor interaction
pon04514	Cell adhesion molecules (CAMs)
pon04810	Regulation of actin cytoskeleton
pon05410	Hypertrophic cardiomyopathy (HCM)
pon05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
pon05414	Dilated cardiomyopathy

Class

Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:pon04151]
Environmental Information Processing; Signaling molecules and interaction; ECM-receptor interaction [PATH:pon04512]
Environmental Information Processing; Signaling molecules and interaction; Cell adhesion molecules (CAMs) [PATH:pon04514]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:pon04810]
Cellular Processes; Cell communication; Focal adhesion [PATH:pon04510]
Human Diseases; Cardiovascular diseases; Hypertrophic cardiomyopathy (HCM) [PATH:pon05410]
Human Diseases; Cardiovascular diseases; Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:pon05412]
Human Diseases; Cardiovascular diseases; Dilated cardiomyopathy (DCM) [PATH:pon05414]

SSDB

Motif

Pfam:

Integrin_alpha2 FG-GAP VCBS

Other DBs

NCBI-GI:

297686097

NCBI-GeneID:

100442074

Ensembl:

ENSPPYG00000002116

Position

AA seq 922 aa
MSTGASRGPRGSQAPLIAPLCCAAAALGMMLWSPASQAFNLDVEKLTVYSGPKGSYFGYA
VDFHIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIR
VNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSA
YAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANY
SFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGVPRGAQNFGYVSI
INSTDMMFIQNFTGEQMASYFGYTIVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQI
YLYLQVSSLLFRDPQILIGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVL
IYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAV
YRARPVVTVDAQLLLHPMIINLENKTCQLPDSMTSAACFSLRVCASVTGQSIANTIVLMA
EVQLDSLKQKGAIKRTLFLENHQAHRIFPLVIKWQKSHQCQDFIVYLRDETEFRDKLSPI
NISLNYSLDESIFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARTDKH
QVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENV
TRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSITRHFNLQIRSSNKDNPDSNFVSLQ
INITAVAQVEIRGVSHPPQIVLPIQNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDT
ILEVGWPFSARDEFLLYIFHIQTLGPLQCHTNPNINPQDIKIKTSVIWATPNVSFSIPLW
VIILAILLGLLVLAILTLALWK

NT seq 2766 nt +upstreamnt +downstreamnt
atgtcgaccggggccagccgcggtccccggggaagccaggcgccgctgatcgcgcccctc
tgctgcgccgcggcagcgctggggatgatgctgtggtcccctgcctctcaggcgttcaac
ctggacgtggaaaagctcacggtgtacagcggccccaagggcagctacttcggctacgcc
gtggacttccacatacccgacgcccgcacagcgagtgtcttggtgggggcgccgaaagcc
aacaccagccagcccgatatcgtggaagggggagccgtctattactgtccttggcccgcg
gaggggtctgcgcagtgcaggcagataccgtttgacaccaccaacaacagaaagatcaga
gttaatggaaccaaagaacctatcgagttcaaatccaatcagtggtttggagcaacagtg
aaagctcacaaaggaaaagttgtggcctgtgctcctttatatcactggagaactcttaaa
ccgacaccagaaaaggacccagttggcacctgctatgtagcaattcagaacttcagcgcc
tatgccgagttctctccttgccggaacagcaatgctgatccggaaggccagggttactgc
caagcaggatttagtctggatttttataagaatggagaccttattgtgggaggacctggg
agtttctactggcaagggcaagtgatcactgccagtgttgcagatatcattgcaaattac
tcattcaaggatatcctcaggaaattggcaggagaaaagcagacggaagtggctccagct
tcctatgatgacagttaccttggatactcagttgctgctggggagtttactggggattct
cagcaagaattggttgctggagttccaagaggagcacagaattttggatatgtttcaatc
attaactctacggatatgatgtttattcagaatttcactggcgaacagatggcatcttat
tttggatataccattgtcgtatcagatgttaacagtgacggactggatgatgtcctggtt
ggagcacctctctttatggaacgtgaatttgagagcaaccccagagaagtagggcaaatc
tacctgtatttgcaagtgagctctctcctcttcagagacccccagatcctcatcggcacc
gagacgtttgggagattcggtagtgctatggcgcacttaggagacctgaaccaagatgga
tacaatgacattgccatcggcgtgccttttgcaggcaaggatcaaagaggcaaagtgctc
atttataatgggaacaaagatggcttaaacaccaagccttcccaagttctgcaaggagtg
tgggcctcacacgctgtcccttctggatttggctttactttaagaggagattcagacata
gacaagaatgattacccagatttgattgtgggtgcatttggaacaggaaaagtcgctgtt
tacagagcaagaccggttgtgactgtagatgcccagcttctgctgcacccaatgattatc
aatcttgaaaataaaacttgccagcttccagactctatgacatctgcagcctgcttttct
ttaagagtatgtgcatctgtcacaggccagagcattgcaaacacaatagtcttgatggca
gaggtgcaattagattccctgaaacagaaaggagccattaaacggacactcttccttgaa
aaccatcaggctcatcgcatcttccctcttgttataaaatggcagaaatcccaccagtgc
caggatttcatcgtttaccttcgagatgaaactgaattccgagataaattatctccaatc
aacattagtttgaattacagtttggacgaatccatctttaaagaaggcctggaagtgaaa
ccaatattgaactactacagagaaaacattgttagtgaacaggctcacattctggtggac
tgtggagaagacaatctgtgtgttcctgacttgaagctgtcggctagaacagataagcat
caggtaatcattggagatgaaaatcaccttatgctcataataaatgcaagaaatgaaggg
gaaggagcatatgaagctgaactctttgtaatgataccagaagaggcagattatgttggg
atcgaacgcaacaacaagggatttcgaccactgagctgtgagtacaagatggaaaatgta
accaggatggtagtgtgcgaccttgggaaccctatggtgtctggaacaaattattccctg
ggcctccgatttgcagttccacgtcttgagaaaacaaacatgagcattacacggcacttc
aatctccaaatcagaagttccaacaaggacaatccagacagcaattttgtgagcctgcaa
atcaacatcactgctgtagcacaggtggaaataagaggagtgtcacaccctccgcagatt
gttctgcccattcaaaactgggaaccagaagaggagccccacaaagaggaggaggttgga
ccattggtggaacatatttatgagctgcacaatattggaccaagtaccatcagtgacacc
atcctggaggtgggctggcctttctctgcccgggatgaatttcttctctatattttccat
attcaaactctgggacctctgcagtgccacactaatcctaatatcaatccacaggatata
aagattaagacatcagttatttgggcaactccaaatgtttccttctcaatcccattatgg
gtaataatactagcaatacttcttggattgttggttctggccattttaaccttagcttta
tggaag

All links

Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   ENSEMBL-PON (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (19)   

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