KEGG   Pongo abelii (Sumatran orangutan): 100445634Help
Entry
100445634         CDS       T01416                                 

Gene name
CREBBP
Definition
(RefSeq) LOW QUALITY PROTEIN: CREB-binding protein
  KO
K04498  E1A/CREB-binding protein [EC:2.3.1.48]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04024  cAMP signaling pathway
pon04066  HIF-1 signaling pathway
pon04068  FoxO signaling pathway
pon04110  Cell cycle
pon04310  Wnt signaling pathway
pon04330  Notch signaling pathway
pon04350  TGF-beta signaling pathway
pon04520  Adherens junction
pon04630  Jak-STAT signaling pathway
pon04720  Long-term potentiation
pon04916  Melanogenesis
pon04919  Thyroid hormone signaling pathway
pon04922  Glucagon signaling pathway
pon05016  Huntington's disease
pon05152  Tuberculosis
pon05161  Hepatitis B
pon05164  Influenza A
pon05165  Human papillomavirus infection
pon05166  HTLV-I infection
pon05167  Kaposi's sarcoma-associated herpesvirus infection
pon05168  Herpes simplex infection
pon05169  Epstein-Barr virus infection
pon05200  Pathways in cancer
pon05203  Viral carcinogenesis
pon05206  MicroRNAs in cancer
pon05211  Renal cell carcinoma
pon05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    100445634 (CREBBP)
   04330 Notch signaling pathway
    100445634 (CREBBP)
   04350 TGF-beta signaling pathway
    100445634 (CREBBP)
   04630 Jak-STAT signaling pathway
    100445634 (CREBBP)
   04066 HIF-1 signaling pathway
    100445634 (CREBBP)
   04068 FoxO signaling pathway
    100445634 (CREBBP)
   04024 cAMP signaling pathway
    100445634 (CREBBP)
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    100445634 (CREBBP)
  Cellular community - eukaryotes
   04520 Adherens junction
    100445634 (CREBBP)
 Organismal Systems
  Endocrine system
   04922 Glucagon signaling pathway
    100445634 (CREBBP)
   04919 Thyroid hormone signaling pathway
    100445634 (CREBBP)
   04916 Melanogenesis
    100445634 (CREBBP)
  Nervous system
   04720 Long-term potentiation
    100445634 (CREBBP)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100445634 (CREBBP)
   05206 MicroRNAs in cancer
    100445634 (CREBBP)
   05203 Viral carcinogenesis
    100445634 (CREBBP)
   05211 Renal cell carcinoma
    100445634 (CREBBP)
   05215 Prostate cancer
    100445634 (CREBBP)
  Neurodegenerative diseases
   05016 Huntington's disease
    100445634 (CREBBP)
  Infectious diseases
   05152 Tuberculosis
    100445634 (CREBBP)
   05166 HTLV-I infection
    100445634 (CREBBP)
   05164 Influenza A
    100445634 (CREBBP)
   05161 Hepatitis B
    100445634 (CREBBP)
   05168 Herpes simplex infection
    100445634 (CREBBP)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    100445634 (CREBBP)
   05169 Epstein-Barr virus infection
    100445634 (CREBBP)
   05165 Human papillomavirus infection
    100445634 (CREBBP)
Enzymes [BR:pon01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     100445634 (CREBBP)
Transcription factors [BR:pon03000]
 Eukaryotic Type
  Other transcription factors
   Pocket domain CBP
    100445634 (CREBBP)
Chromosome [BR:pon03036]
 Eukaryotic Type
  Histone modification proteins
   HATs (histone acetyltransferases)
    100445634 (CREBBP)
Mitochondrial biogenesis [BR:pon03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Coactivators
    100445634 (CREBBP)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: HAT_KAT11 KIX Creb_binding zf-TAZ DUF902 Bromodomain ZZ KIX_2 Npa1
Motif
Other DBs
NCBI-GeneID: 100445634
NCBI-ProteinID: XP_002826106
Ensembl: ENSPPYG00000007051
Position
16
AA seq 2439 aa AA seqDB search
MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
SPLSQGDSSAPSLPKQTASTSGPTPPASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGATSSVLA
ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMSSVPGMAISPSRMPQPPNMMGAHT
NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQTEDTEPDPGESKGEPRSE
MMEEDLQGASQVKEETDTAEQKSEPMEVDEKKPEVKVEVKEEEESSTNGTASQSTSPSQP
RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDSCLKKTGRPRK
ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPTQPQPSPVSMSPAG
FPSVARTQPPTTVSTGKPTSQVPXPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNG
MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQGSAGMAG
GMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADS
TPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQV
RSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNP
EQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
NT seq 7320 nt NT seq  +upstreamnt  +downstreamnt
atggccgagaacttgctggacggaccgcccaaccccaaaagagccaaactcagctcgccc
ggtttctcggcgaatgacagcacagattttggatcattgtttgacttggaaaatgatctt
cctgatgagctgatacccaatggaggagaattaggccttttaaacagtgggaaccttgtt
ccagatgctgcttccaaacataaacaactgtcggagcttctacgaggaggcagcggctct
agtatcaacccaggaataggaaatgtgagcgccagcagccccgtgcagcagggcctgggt
ggccaggctcaagggcagccgaacagtgcgaacatggccagcctcagtgccatgggcaag
agccctctgagccagggagattcttcagcccccagcctgcccaaacagacagccagcacc
tctgggcccaccccccctgcctcccaagcactgaatccgcaagcacaaaagcaagtgggg
ctggcgactagcagccctgccacgtcacagactggacctggtatctgcatgaatgctaac
tttaaccagacccacccaggcctcctcaatagtaactctggccatagcttaattaatcag
gcttcacaagggcaggcgcaagtcatgaatggatctcttggggctgctggcagaggaagg
ggagctggaatgccgtaccctactccagccatgcagggcgccacaagcagtgtgctggct
gagaccctaacgcaggtttccccgcaaatgactggtcacgcgggactgaacaccgcacag
gcaggaggcatggctaagatgggaataactgggaacacaagtccatttggacagcccttt
agtcaagctggagggcagccaatgggagccactggagtgaacccccagttagccagcaaa
cagagcatggtcaacagtttgcccaccttccctacagacatcaagaatacttcagtcacc
aacgtgccaaatatgtctcagatgcaaacatcagtgggaattgtacccacacaagcaatt
gcaacaggccccactgcagatcctgaaaaacgcaaactgatacagcagcagctggttcta
ctgcttcatgctcataagtgtcagagacgagagcaagcaaacggagaggttcgggcctgc
tcgctcccacattgtcgaaccatgaaaaacgttttgaatcacatgacgcattgtcaggct
gggaaagcctgccaagttgcccattgtgcatcttcacgacaaatcatctctcattggaag
aactgcacacgacatgactgtcctgtttgcctccctttgaaaaatgccagtgacaagcga
aaccaacaaaccatcctggggtctccagctagtggaattcaaaacacaattggttctgtt
ggcacagggcaacagaatgctacttctttaagtaacccaaatcccatagaccccagctcc
atgcagcgagcctatgctgctctcggactcccctacatgaaccagccccagacgcagctg
cagcctcaggttcctggccagcaaccagcacagcctcaaacccaccagcagatgaggact
ctcaaccccctgggaaataatccaatgaacattccagcaggaggaataacaacagatcag
cagcccccaaacttgatttcagaatcagctcttccgacttccctgggggccacaaaccca
ctgatgaacgatggctccaactctggtaacattggaaccctcagcactataccaacagca
gctcctccttctagcaccggtgtaaggaaaggctggcacgaacatgtcactcaggacctg
cggagccatctagtgcataaactcgtccaagccatcttcccaacacctgatcccgcagct
ctaaaggatcgccgcatggaaaacctggtagcctatgctaagaaagtggaaggggacatg
tacgagtctgccaacagcagggatgaatattatcacttattagcagagaaaatctacaag
atacaaaaagaactagaagaaaaacggaggtcgcgtttacataaacaaggcatcttgggg
aaccagccagccttaccagccccgggggctcagccacctgtgattccacaggcacaacct
gtgagacctccaaatggacccctgtccctgccagtgaatcgcatgcaagtttctcaaggg
atgaattcatttaaccccatgtccttggggaacgtccagttgccacaagcacccatggga
cctcgtgcagcctccccaatgaaccactctgtccagatgaacagcatgagctcagtgcca
gggatggccatttctccttcccgaatgcctcagcctccgaacatgatgggcgcacacacc
aacaacatgatggcccaggcacctgctcagagccagtttctgccacagaaccagttccca
tcatccagcggggcgatgagtgtgggcatggggcagccgccagcccaaacaggcgtgtca
cagggacaggtgcctggtgctgctcttcctaaccctctcaacatgctggggcctcaggcc
agccagctgccttgccctccagtgacacagtcaccactgcacccaacaccgcctcctgct
tccacggctgctggcatgccatctctccagcacacgacaccacctgggatgactcctccc
cagccagcagctcccactcagccatcaactcctgtgtcgtcttccgggcagactcccacc
ccgactcctggctcagtgcccagtgctacccaaacccagagcacccctacagtccaagca
gcagcccaggcccaggtgaccccgcagcctcaaaccccagttcagcccccgtctgtggct
acccctcagtcatcacagcaacagccgacgcccgtgcacgcccagcctcctggcacaccg
ctttcccaggcagcagccagcattgataacagagtccctaccccctcctcggtggccagc
gcagaaaccaattcccagcagccgggacctgacgtacctgtgctggaaatgaagacggag
acccagacagaggacactgagcccgatcctggtgaatccaaaggggagcccaggtctgag
atgatggaggaggatttgcaaggagcttcccaagttaaagaagaaacagacacagcagag
cagaaatcagaaccaatggaagtggatgaaaagaaacctgaagtgaaagtagaagttaaa
gaggaagaagagagtagcactaacggcacagcctctcagtcaacatctccttcgcaacca
cgcaaaaaaatctttaaaccagaggagttacgccaggccctcatgccaaccctagaagca
ctgtatcgacaggacccagagtcgttacctttccggcagcctgtagatccccagctcctc
ggaattccagactattttgacatcgtaaagaatcccatggacctctccaccatcaagcgg
aagctggacacagggcaataccaagagccctggcagtatgtggacgacgtctggctcatg
ttcaacaatgcctggctctataatcgcaagacatcccgagtctataagttttgcagtaag
cttgcagaggtctttgagcaggaaattgaccctgtcatgcagtcccttggatattgctgt
ggacgcaagtatgagttttccccgcagactttgtgctgctatgggaagcagctgtgtacc
attcctcgcgatgctgcctactacagctatcagaataggtatcatttctgtgagaagtgt
ttcacagagatccagggcgagaatgtgaccctgggtgacgacccttcacagccccagacg
acaatttcaaaggatcagtttgaaaagaagaaaaatgataccttagaccccgaacctttc
gttgattgcaaggagtgtggccggaagatgcatcagatttgcgttctgcactatgacatc
atttggccttcaggttttgtgtgcgacagctgcttgaagaaaactggcagacctcgaaaa
gaaaacaaattcagtgctaagaggctgcagaccacaagactgggaaaccacttggaagac
cgagtgaacaaatttttgcggcgacagaatcaccctgaagccggggaggtttttgtccga
gtggtggccagctcagacaagacggtggaggtcaagcccgggatgaagtcacggtttgtg
gattctggggaaatgtctgaatctttcccatatcgaaccaaagctctgtttgcttttgag
gaaattgacggcgtggatgtctgcttttttggaatgcacgtccaagaatatggctctgat
tgcccccctccaaacacaaggcgtgtgtacatttcttatctggatagtattcatttcttc
cggccacgttgcctccgcacagccgtttaccatgagatccttattggatatttagagtat
gtgaagaaattggggtacgtgacagggcacatctgggcctgtcctccaagtgaaggagat
gattacatcttccattgccacccacctgatcaaaaaatacccaagccaaaacgactgcag
gagtggtacaaaaagatgctggacaaggcgtttgcagagcggatcattcatgactacaag
gatattttcaaacaagcaactgaagacaggctcaccagtgccaaggaactgccctatttt
gaaggtgatttctggcccaatgtgttagaagagagcattaaggaactagaacaagaagaa
gaggagaggaaaaaggaagagagcactgcagccagtgaaactactgagggcagtcagggc
gacagcaagaatgccaagaagaagaacaacaagaaaaccaacaagaacaaaagcagcatc
agccgcgccaacaagaagaagcccagcatgcccaacgtgtccaatgacctatcccagaag
ctgtatgccaccatggagaagcacaaggaggtcttcttcgtgatccacctgcacgctggg
cctgtcatcaacaccctgccccccatcgtcgaccccgaccccctgctcagctgtgacctc
atggatgggcgcgacgccttcctcacactcgccagagacaagcactgggagttctcctcc
ttgcgccgctccaagtggtccacgctctgcatgctggtggagctgcacacccagggccag
gaccgctttgtctacacctgcaacgagtgcaagcaccacgtggagacgcgctggcactgc
actgtgtgcgaggactacgacctctgcatcaactgctataacacgaagagccatgcccat
aagatggtgaagtgggggctgggcctggatgacgagggcagcagccagggcgagccacag
tcaaagagcccccaggagtcacgacggctgagcatccagcgctgcatccagtcgctggtg
cacgcgtgccagtgccgcaacgccaactgctcgctgccatcctgccagaagatgaagcgg
gtggtgcagcacaccaagggctgcaaacggaagaccaatgggggctgcccggtgtgcaag
cagctcatcgccctctgctgctaccacgccaagcactgccaagaaaacaaatgccccgtg
cccttctgcctcaacatcaaacacaagctccgccagcagcagatccagcaccgcctgcag
caggcccagctcatgcgccggcggatggccaccatgaacacccgcaacgtgcctcagcag
agtctgccttctcctacctcagcaccgcccgggacccccacacagcagcccagcacgccc
cagacgccgcagccccccacccagccccaaccctcacccgtgagcatgtcaccagctggc
ttccccagcgtggcccggactcagccccccaccacggtgtccacagggaagcctaccagc
caggtgccgngccccccacccccggcccagccccctcctgcagcagtggaagcagctcgg
cagatcgaacgtgaggcccagcagcagcagcacctgtaccgggtgaacatcaacaatggc
atgcccccaggacgcacgggcatggggaccccggggagccagatggcccccgtgagcctg
aatgtgccccgacccaaccaggtgagcgggccggtcatgcccagcatgcctcccgggcag
tggcagcaggcgccccttccccagcagcagcccatgccaggcttgcccaggcctgtgata
tccatgcaggcccaggcggccgtggccgggccccggatgcccagcgtgcagccgcccagg
agcatttcacccagcgctctgcaagacctgctgcggaccctgaagtcgcccagctcccct
cagcagcaacagcaggtgctgaacattctcaaatcaaacccgcagctaatggcagctttc
atcaaacagcgcacagccaagtacgtggccaatcagcccggcatgcagccccagcctggc
ctccagtcccagcccggcatgcaaccccagcctggcatgcaccagcagcccagcctgcag
aacctgaatgccatgcaggctggcgtgccgcggcccggtgtgcctccacagcagcaggca
atgggaggcctgaacccccagggccaggccttgaacatcatgaacccaggacacaacccc
aacatggcgagtatgaatccacagtaccgagaaatgctacggaggcagctgctgcagcag
cagcagcaacaacagcaacaacagcagcagcagcagcaagggagtgccggcatggctggg
ggcatggcggggcacggccagttccagcagcctcaaggacccggaggctacccaccggcc
atgcagcagcagcagcgcatgcagcagcatctccccctccagggcagctccatgggccag
atggcggctcagatgggacagcttggccagatggggcagccggggctgggggcagacagc
acccccaacatccagcaagccctgcagcagcggattctgcagcaacagcagatgaagcag
cagattgggtccccaggccaaccaaaccccatgagcccccagcaacacatgctctcagga
cagccacaggcctcgcatctccctggccagcagatcgccacatcccttagtaaccaggtg
cggtctccagcccctgtccagtctccacggccccagtcccagcctccacattccagcccg
tcaccacggatacagccccagccttcaccacaccacgtctcaccccagactggttccccc
caccccggactcgcagtcaccatggccagctccatagatcagggacacttggggaacccc
gaacagagtgcaatgctcccccagctgaacacccccagcaggagtgcgctgtccagcgaa
ctgtccctggtcggggacaccacgggggacacgctagagaagtttgtggagggcttgtag

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