KEGG   Pongo abelii (Sumatran orangutan): 100446928Help
Entry
100446928         CDS       T01416                                 

Gene name
UGT2B4
Definition
(RefSeq) UDP-glucuronosyltransferase 2B4 isoform X4
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00040  Pentose and glucuronate interconversions
pon00053  Ascorbate and aldarate metabolism
pon00140  Steroid hormone biosynthesis
pon00830  Retinol metabolism
pon00860  Porphyrin and chlorophyll metabolism
pon00980  Metabolism of xenobiotics by cytochrome P450
pon00982  Drug metabolism - cytochrome P450
pon00983  Drug metabolism - other enzymes
pon01100  Metabolic pathways
pon05204  Chemical carcinogenesis
Module
pon_M00014  Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:pon00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    100446928 (UGT2B4)
   00053 Ascorbate and aldarate metabolism
    100446928 (UGT2B4)
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    100446928 (UGT2B4)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100446928 (UGT2B4)
   00860 Porphyrin and chlorophyll metabolism
    100446928 (UGT2B4)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100446928 (UGT2B4)
   00982 Drug metabolism - cytochrome P450
    100446928 (UGT2B4)
   00983 Drug metabolism - other enzymes
    100446928 (UGT2B4)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    100446928 (UGT2B4)
Enzymes [BR:pon01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     100446928 (UGT2B4)
Glycosyltransferases [BR:pon01003]
 Others
  Hydrophobic molecule
   100446928 (UGT2B4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: UDPGT Glyco_tran_28_C Pro_3_hydrox_C
Motif
Other DBs
NCBI-GeneID: 100446928
NCBI-ProteinID: XP_009238323
Ensembl: ENSPPYG00000014789
Position
4
AA seq 392 aa AA seqDB search
MFFALLHVSSTNGLDAIFPFGELLAELLKIPFVYSLRFSPGYAIEKHSGGLLFPPSYVPV
VMSELSDQMTFMERVKNMIYVLYFDFWFQIFDMKKWDQFYSEVLGRPTTLSETMAKAEIW
LIRNYWDFQFPHPLLPNVEFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVSNT
SEERANVIASALAKIPQKVLWRFDGNKPDTLGLNTRLYKWLPQNDLLGHPKTRAFITHGG
ANGVYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLDFNTMSSTDLLNALKTVINDP
LYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGF
LLACVATVILIITKCLFCVWKFVRTGKKGKRD
NT seq 1179 nt NT seq  +upstreamnt  +downstreamnt
atgttttttgctctcttacatgtatcatcaacgaatggattagatgctattttccccttt
ggtgagctgctggctgagctacttaaaataccctttgtctacagcctccgcttctctcct
ggctacgcaattgaaaagcatagtggaggacttctgttccctccttcctatgtgcctgtt
gttatgtcagaattaagtgatcaaatgactttcatggagagggtaaaaaatatgatctat
gtgctttattttgacttttggttccaaatatttgacatgaagaagtgggatcagttctac
agtgaagttctaggaagacccactacattatctgagacaatggcaaaagctgaaatatgg
cttattcgaaactactgggattttcaatttcctcacccactcttaccaaatgttgagttc
gttggaggactccactgcaaacctgccaaacccctacctaaggaaatggaagagtttgtc
cagagctctggagaaaatggtgttgtggtgttttctctggggtcgatggtcagtaacaca
tcagaagaaagggccaatgtaattgcatcagcccttgccaagatcccacaaaaggttctg
tggagatttgatgggaataaaccagatactttaggactcaatactcggctgtacaagtgg
ctaccccagaatgatcttcttggtcacccaaaaaccagagcttttataactcatggtgga
gccaatggcgtctacgaggcgatctaccatggaatccctatggtgggcgttccattgttt
gcagatcaacctgataacattgcacacatgaaggccaagggtgcagctgttagtttggac
ttcaacacaatgtcgagtacagacttactcaatgccctgaagacagtaattaatgatcct
ttatataaagagaatgctatgaaattatcaagaattcatcatgatcaaccagtgaagccc
ctggatcgagcagtcttctggattgaatttgtcatgcgccataaaggagccaaacacctt
cgggttgcagcccacgacctcacctggttccagtaccactctttggatgtgattgggttc
ctcctggcctgtgtggcaactgtgatactcatcatcacaaaatgtctgttttgtgtctgg
aagtttgttagaacaggaaagaaggggaaaagagattaa

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