KEGG   Pongo abelii (Sumatran orangutan): 100448999Help
Entry
100448999         CDS       T01416                                 

Gene name
CACNA2D3
Definition
calcium channel, voltage-dependent, alpha 2/delta subunit 3
Orthology
K04860  
voltage-dependent calcium channel alpha-2/delta-3
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
MAPK signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Oxytocin signaling pathway
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pon00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    100448999 (CACNA2D3)
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    100448999 (CACNA2D3)
  Circulatory system
   04260 Cardiac muscle contraction
    100448999 (CACNA2D3)
   04261 Adrenergic signaling in cardiomyocytes
    100448999 (CACNA2D3)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100448999 (CACNA2D3)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    100448999 (CACNA2D3)
   05414 Dilated cardiomyopathy (DCM)
    100448999 (CACNA2D3)
Ion channels [BR:pon04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-2 delta
   100448999 (CACNA2D3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
3
AA seq 987 aa AA seqDB search
MCLVSSTLPGIPETPSIFVVDSCVCSLGEGSKLTLQRPCGGTINSHDFKCALMAWSSRKY
KEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADLQYEY
FNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVY
WSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQA
ATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNG
TLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICSQAIMLITD
GAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQEN
VMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLTDDQGPVLMTTVAMPVFSKQNET
RSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRLLYEEGKKRR
KPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIK
GTPFRLELMSLLSAVPIISGYDFYQKDQRLHDLEHPDVSLADEWSYCNTDLHPEHRHLSQ
LEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLG
TRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFST
GPVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCASVDGKCSISC
DDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAVMNKLLTMGSFKRITLYDYQAMCRA
NKESSDGAHGLLDPYNAFLSAVKWIMTELVLFLVEFNLCSWWHSDMTTKAQKLKQTLEPC
DTEYPAFVSERTIKETTGNIACEDCSK
NT seq 2964 nt NT seq  +upstreamnt  +downstreamnt
atgtgcttggtgtctagcaccctgcctggcataccagagacaccaagtatttttgttgtt
gacagctgtgtctgctccttgggggaaggctccaagctcaccctgcagaggccctgtgga
ggaacaatcaactctcatgacttcaaatgtgccctgatggcctggagcagtcgtaaatac
aaagagtatgagaaagatgttgccatagaagaaatcgatggcctccaactggtaaagaag
ctggcaaagaacatggaagagatgtttcacaagaagtctgaggcagtcaggcgtctggtg
gaggctgcagaagaagcacacctgaaacatgaatttgatgcagacttacagtatgaatac
ttcaatgctgtgctgataaatgaaagggacaaagacgggaattttttggagctgggaaag
gaattcatcttagccccaaatgaccattttaataatttgcctgtgaacatcagtctaagt
gacgtccaagtaccaacgaacatgtacaacaaagaccctgcaattgtcaatggtgtttat
tggtctgaatccctaaacaaagtttttgtagataactttgaccgtgacccgtctctcata
tggcagtacttcggaagtgcaaagggctttttcaggcagtatccggggattaaatgggaa
ccagatgagaatggagtcattgccttcgactgcaggaaccgaaaatggtacatccaggca
gcaacttctccgaaagacgtggtcattttagttgacgtcagtggcagcatgaaaggactc
cgtctcactatcgcgaagcaaacagtctcatccattttggatacacttggcgatgatgac
ttcttcaacataattgcttataatgaggagcttcactatgtggaaccttgcctgaatgga
actttggtgcaagccgacaggacaaacaaagagcacttcagggagcatctggacaaactt
tttgccaaaggaattggaatgttggatatagctctgaatgaggccttcaacattctgagt
gatttcaaccacacgggacaaggaagtatctgcagtcaggccatcatgctcataactgat
ggggcagtggacacctatgatacaatctttgcgaaatacaattggccagatcgaaaggtt
cgcatcttcacatacctcattggacgagaggctgcgtttgcagacaatctaaagtggatg
gcctgtgccaacaaaggattttttacccagatctccaccttggctgatgtgcaggagaat
gtcatggaataccttcacgtgctcagccggcctaaagtcatcgaccaggagcatgatgtg
gtgtggaccgaagcttacattgacagcactctccctcaggcacaaaagctgactgatgat
cagggccccgtcctgatgaccactgtagccatgcctgtgtttagtaagcagaacgaaacc
agatcgaagggcattctcctgggagtggttggcacagatgtcccagtgaaagaacttttg
aagaccatccccaaatacaagttagggattcacggttatgcctttgcaatcacaaataat
ggatatatcctgacacatccagaactcaggctgctgtatgaagaaggaaaaaagcgaagg
aaacctaactatagtagcgttgacctctctgaggtggagtgggaagaccgagatgatgtg
ttgagaaatgctatggtgaatcgaaagacggggaagttttccatggaggtgaagaagaca
gtggacaaagggaaacgggttttggtgatgacaaatgactactattatacagacatcaag
ggtactcctttcagattagagcttatgtcattattgtcagcagttccaatcatcagtgga
tatgatttttatcagaaggaccaacgcctgcatgacttagaacatcccgatgtgtccttg
gcagatgaatggtcctactgcaacactgacctacaccctgagcaccgccatctgtctcag
ttagaagcgattaagctctacctaaaaggcaaagaacctctgctccagtgtgataaagaa
ttgatccaagaagtcctttttgacgccgtggtgagtgcccccattgaagcgtattggacc
agcctggccctcaacaaatctgagaattctgacaagggcgtggaggttgccttcctcggc
actcgcacgggcctctccagaatcaacctgtttgtcggggctgagcagctcaccaatcag
gacttcctgaaagctggcgacaaggagaacatttttaacgcagaccatttccctctctgg
taccgaagagctgctgagcagattccagggagctttgtctactcgatcccgttcagcact
ggaccagtcaataaaagcaatgtggtgacagcgagtacatccatccagctcctggatgaa
cggaaatctcctgtggtggcagctgtaggcattcagatgaaacttgaatttttccaaagg
aagttctggactgccagcagacagtgtgcctccgtggatggcaaatgctccatcagctgt
gatgatgagactgtgaattgttacctcatagacaataatggatttattttggtgtctgaa
gactacacacagactggagacttttttggtgagatcgagggagctgtgatgaacaaattg
ctaacaatgggctcctttaaaagaattacactttatgactaccaagccatgtgtagagcc
aacaaggaaagcagcgatggcgcccatggcctcctggatccttataatgccttcctctct
gcagtaaaatggatcatgacagaacttgtcttgttcctggtggaatttaacctctgcagt
tggtggcactccgatatgacaactaaagcccagaaattgaaacagaccctggagccttgt
gatactgaatatccagcatttgtctctgagcgcactatcaaggagactacagggaatatt
gcttgtgaagactgctccaagtaa

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