KEGG   Pongo abelii (Sumatran orangutan): 100450941Help
Entry
100450941         CDS       T01416                                 

Gene name
PLCG1
Definition
phospholipase C, gamma 1
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:pon00562]
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:pon04014]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:pon04015]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:pon04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:pon04370]
Environmental Information Processing; Signal transduction; NF-kappa B signaling pathway [PATH:pon04064]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:pon04066]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:pon04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:pon04070]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:pon04650]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:pon04660]
Organismal Systems; Immune system; Fc epsilon RI signaling pathway [PATH:pon04664]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:pon04666]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:pon04670]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:pon04919]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:pon04722]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:pon04750]
Human Diseases; Cancers; Pathways in cancer [PATH:pon05200]
Human Diseases; Cancers; MicroRNAs in cancer [PATH:pon05206]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:pon05205]
Human Diseases; Cancers; Glioma [PATH:pon05214]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:pon05223]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:pon05169]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
20
AA seq 1299 aa AA seqDB search
MTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQ
EDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIE
RWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFA
QLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQ
EFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSS
HNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVL
HTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQ
LKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTS
SKIYYSEETSSDQGNEDEEEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCI
ETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYD
LITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR
KRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRY
PINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTK
SAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRG
VLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTAD
ARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNK
VKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALF
MTGRHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAISVEVLGARHLPKNGRGIVCPFVEI
EVAGAEYDSTKQKTEFVGQSVFTVILLILLILLGHCKPLPTSHPILSQGDLKPFVVAFTV
DNGLNPVWPAKPFHFQIINPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPL
KNNYSEDLELASLLIKIDIFPAKQENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFES
RYQQPFEDFRISQEHLTDHFDSRERRAPRRTRVNGDNRL
NT seq 3900 nt NT seq  +upstreamnt  +downstreamnt
atgactttgttctactccaagaagtcgcagcgaccagagcggaagaccttccaggtcaag
ctggagacgcgccagatcacgtggagccgtggtgccgacaagatcgagggggccattgat
attcgtgaaattaaggagatccgcccagggaagacctcacgggactttgatcgctatcaa
gaggacccagctttccggccggaccagtcacattgctttgtcattctctatggaatggaa
tttcgcctgaaaacgctgagcctgcaagccacatctgaggatgaagtgaacatgtggatc
aagggcttaacttggctgatggaggatacattgcaggcacccacaccgctgcagattgag
aggtggctccggaagcagttttactcagtggatcggaatcgtgaggatcgtatatcagcc
aaggacctgaagaacatgctgtcccaggtcaactaccgggtccccaacatgcgcttcctc
cgagagcggctgacggacctggagcagcgcagcggggacatcacctacgggcagtttgct
cagctgtaccgcagcctcatgtacagcgcccagaagacgatggacctccccttcttggaa
gccagtactctgagggctggggagcggccggagctttgccgagtgtcccttcctgagttc
cagcagttccttcttgactaccagggggagctgtgggctgttgatcgcctccaggtgcag
gagttcatgctcagcttcctccgagaccccttacgagagatcgaggagccatacttcttc
ctggatgagtttgtcaccttcctgttctccaaagagaacagtgtgtggaactcacagctg
gatgcagtatgcccggacaccatgaacaaccctctttcccactactggatctcctcctcg
cacaacacgtacctgaccggggaccagttctccagtgagtcctccttggaagcctatgct
cgctgcctgcggatgggctgtcgctgcattgagttggactgctgggacggcccagatggg
atgccagttatttaccatggtcacacccttaccaccaagatcaagttctcagatgtcctg
cataccatcaaggagcatgcctttgtggcctcagagtacccagtcatcctgtccattgag
gaccactgcagcattgcccagcagaggaacatggcccagtacttcaagaaggtgctgggg
gacacactcctcaccaagcccgtggagatctccgccgatgggctcccctcacccaaccag
cttaagaggaagatccttatcaagcacaagaagctggctgagggcagtgcctatgaggag
gtgcctacatccatgatgtactctgagaacgacatcagcaactccatcaagaatggcatc
ctctacctggaggaccctgtgaaccacgaatggtatccccactactttgttctgaccagc
agcaagatctactactctgaggagaccagcagtgaccagggcaacgaggatgaggaggag
cccaaggaggtcagcagcagcacagagctgcactccaatgagaagtggttccatgggaag
ctaggggcagggcgtgacgggcgtcacatcgctgagcgcctgctcactgagtactgcatc
gagactggagcccctgacggctccttcctcgtgcgagagagtgagaccttcgtgggcgac
tacacgctctctttctggcggaacgggaaagtccagcactgccgtatccactcccggcaa
gatgctgggacccccaagttcttcttgacagacaacctcgtctttgactccctctatgac
ctcatcacacactaccagcaggtgcccctgcgctgtaatgagtttgagatgcgactttca
gagcctgtcccacagaccaacgcccacgagagcaaagagtggtaccacgcgagcctgacc
agagcacaggctgagcacatgctaatgcgcgtccctcgtgatggggccttcctggtgcgg
aagcggaatgagcccaactcatatgccatctctttccgggctgagggcaagatcaagcat
tgccgtgtccagcaagagggccagacagtgatgctagggaactcggagttcgacagcctt
gttgacctcatcagctactatgagaaacacccactataccgcaagatgaagctgcgctat
cccatcaacgaggaggcattggagaagattggcacagctgagcctgactacggggccctg
tatgagggacgcaaccctggcttctatgtagaggcaaaccctatgccaactttcaagtgt
gcggtcaaagccctctttgactacaaggcccagagggaggacgagctgaccttcaccaag
agcgccatcatccagaatgtggagaagcaagagggaggctggtggcgaggggactacgga
gggaagaagcagctgtggttcccatcaaactatgtggaagagatggtcaaccccgtggcc
ctggagccggagagggagcacttggacgagaacagccccctaggggacttgctgcggggc
gtcttggatgtgccggcttgtcagattgccatccgtcctgagggcaagaacaaccggctc
ttcgtcttctccatcagcatggcgtcggtggcccactggtccctggatgttgctgccgac
tcacaggaggagctgcaggactgggtgaaaaagatccgtgaagtggcccagaccgcagat
gccaggctcactgaagggaagataatggaacggaggaagaagattgccctggagctctct
gaacttgtcgtctactgccggcctgttcccttcgatgaagagaagattggcacagaacgt
gcttgctaccgggacatgtcatccttcccggaaaccaaggctgagaaatacgtgaacaag
gtcaaaggcaagaagttccttcagtacaatcgactgcagctctcccgcatctaccccaag
ggccagcgactggattcctccaactacgatcctttgcccatgtggatctgtggcagtcag
ctcgtggccctcaacttccagacccctgacaagcctatgcagatgaaccaggccctcttc
atgacgggcaggcactgtggctacgtgctgcagccaagcaccatgcgggatgaggccttc
gacccctttgacaagagcagcctccgcgggctggagccatgtgccatctctgttgaggtg
ctgggggcccgacatctgccaaagaatggccgaggcattgtgtgtccttttgtggagata
gaggtggctggagctgagtatgacagcaccaagcagaagacagagtttgtgggtcagtct
gtcttcacagtcatcctcctcatcctcctcatcctcctggggcactgcaagcccctcccc
accagtcatcccatcctctcccagggtgacctgaagccttttgttgttgccttcacagtg
gacaatggactcaaccctgtatggccagccaagcccttccacttccagatcattaaccct
gaatttgcctttctgcgcttcgtggtgtatgaggaagacatgtttagtgaccagaatttc
ttggctcaggctactttcccagtaaaaggcctgaagacaggatacagagcagtgcctttg
aagaacaactacagtgaggacctggagttggcctccctgctgatcaagattgacattttc
cctgccaagcaggagaatggtgacctcagtcccttcagtggtacgtccctgcgggagcgg
ggctcagatgcctcaggccagctgtttcacggccgagcccgggaaggctcctttgaatcc
cgctaccagcagccatttgaggacttccgcatctcccaggagcatctcacagaccatttt
gacagtcgagaacgaagggccccaagaaggactcgggtcaatggagacaaccgcctctag

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