KEGG   Pongo abelii (Sumatran orangutan): 100451422Help
Entry
100451422         CDS       T01416                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:pon00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100451422 (INSR)
   04015 Rap1 signaling pathway
    100451422 (INSR)
   04010 MAPK signaling pathway
    100451422 (INSR)
   04066 HIF-1 signaling pathway
    100451422 (INSR)
   04068 FoxO signaling pathway
    100451422 (INSR)
   04072 Phospholipase D signaling pathway
    100451422 (INSR)
   04022 cGMP - PKG signaling pathway
    100451422 (INSR)
   04151 PI3K-Akt signaling pathway
    100451422 (INSR)
   04152 AMPK signaling pathway
    100451422 (INSR)
   04150 mTOR signaling pathway
    100451422 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    100451422 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100451422 (INSR)
   04923 Regulation of lipolysis in adipocyte
    100451422 (INSR)
   04913 Ovarian Steroidogenesis
    100451422 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100451422 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    100451422 (INSR)
   04213 Longevity regulating pathway - multiple species
    100451422 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100451422 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100451422 (INSR)
   04931 Insulin resistance
    100451422 (INSR)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100451422 (INSR)
Protein kinases [BR:pon01001]
 Tyrosine protein kinases
  InsR family [OT]
   100451422 (INSR)
Enzyme-linked receptors [BR:pon01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   100451422 (INSR)
Cytokine receptors [BR:pon04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   100451422 (INSR)
CD molecules [BR:pon04090]
 Proteins
  100451422 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
19
AA seq 720 aa AA seqDB search
SPGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFED
YLHNVVFVPRPSRKRRSLGDVGNVTAAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKES
LVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNV
VHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRVR
ATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDG
PLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDII
KGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELM
AHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCM
VAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVL
WEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEI
VNLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVPPVTVSRHLCTREESGGAR
DGRVLCLGFQRGYEETIPYTQLNGGKKNGGILTLPWVQSLLTVPTVAGAGRGSHFRFPLV
NT seq 2163 nt NT seq  +upstreamnt  +downstreamnt
tctccagggctgaagctgccctcgaggacctggtctccaccattcgagtctgaagattct
cagaagcacaaccagagtgagtatgaggattcggccggcgaatgctgctcctgtccaaag
acagactctcagatcctgaaggagctggaggagtcctcgtttaggaagacgtttgaggat
tacctgcacaacgtggtttttgtccccaggccatctcggaaacgcaggtcccttggcgat
gttgggaatgtgacagcggctgtgcccacggtggcagctttccccaacacttcctcaacc
agcgtgcccacgagtccggaggagcacaggccctttgagaaggtggtaaacaaggagtcg
ctggtcatctctggcttgcgacacttcacaggctatcgcatcgagctgcaggcttgcaac
caagacacccctgaggaacggtgcagtgtggcagcctacgtcagtgccaggaccatgcct
gaagccaaggctgatgacatcgtcggccctgtgacgcacgaaatctttgagaacaacgtt
gtccacttgatgtggcaggagccgaaggagcccaatggtctgatcgtgctgtatgaagtg
agttatcggcgatatggcgatgaggagctgcatctctgcgtctcccgcaagcacttcgct
ctggaacggggctgcaggctgcgtgggctgtcgccggggaactacagcgtgcgagtccgg
gccacctcccttgcgggcaacggctcctggacggaacccacctatttctacgtgacagac
tatttagatgtcccgtcaaatattgcaaaaattatcatcggccccctcatctttgtcttt
ctcttcagtgttgtgattggaagtatttatctattcctgagaaagaggcagccagatggg
ccgctgggaccgctttacgcttcttcaaaccctgagtatctcagtgccagtgatgtgttt
ccatgctctgtgtacgtgccggacgagtgggaggtgcctcgagagaagataaccctcctt
cgagagctggggcagggctccttcggcatggtatatgagggcaacgccagggacatcatc
aagggtgaggcagagacccgtgtggcggtgaagacggtcaacgagtcagccagtctccga
gagcggattgaattcctcaatgaggcctcggtcatgaagggcttcacctgccatcacgtg
gtgcgcctcctgggagtggtgtccaagggccagcccacgctggtggtgatggagctgatg
gctcatggagacctgaagagctacctccgttctctgcggccagaggctgagaataatcct
ggccgccctccgcctaccctgcaagagatgattcagatggcggcagagattgctgacggg
atggcctacctgaacgccaagaagtttgtgcatcgggacctggcagcgagaaactgcatg
gtcgcccatgattttactgtcaaaattggagactttggaatgaccagagacatctatgaa
acggattactaccggaaagggggtaagggtctgctccctgtacggtggatggcgccggag
tccctgaaggatggggtctttaccacttcttctgacatgtggtcctttggcgtggtcctt
tgggaaatcaccagcttggcagaacagccttaccaaggcctgtctaatgaacaggtgttg
aaatttgtcatggatggagggtatctggatcaacccgacaactgtccagagagagtcact
gacctcatgcgcatgtgctggcaattcaaccccaagatgaggccaaccttcctggagatt
gtcaacctgctcaaggacgacctgcaccccagctttccggaggtgtcgttcttccacagc
gaggagaacaaggctcccgagagtgaggagctggagatggagtttgaggacatggagaat
gtgccccctgtgaccgtttctcgccacctgtgcacaagggaagagagcgggggggcccgg
gatgggagggtcctctgcttagggtttcagcggggatacgaggaaaccatcccttacaca
caactgaacggaggcaagaaaaacggggggattttgaccttgccttgggtccaatccctc
ctaacagtgcctaccgtggcgggggcaggcagaggttcccattttcgctttcctctggtt
tga

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