KEGG T01416: 100452870

Pongo abelii (Sumatran orangutan): 100452870

Entry

100452870 CDS T01416

Gene name

PRF1

Definition

perforin 1 (pore forming protein)

Orthology

K07818

perforin 1

Organism

pon Pongo abelii (Sumatran orangutan)

Pathway

pon04650	Natural killer cell mediated cytotoxicity
pon04940	Type I diabetes mellitus
pon05320	Autoimmune thyroid disease
pon05330	Allograft rejection
pon05332	Graft-versus-host disease
pon05416	Viral myocarditis

Class

Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:pon04650]
Human Diseases; Immune diseases; Autoimmune thyroid disease [PATH:pon05320]
Human Diseases; Immune diseases; Allograft rejection [PATH:pon05330]
Human Diseases; Immune diseases; Graft-versus-host disease [PATH:pon05332]
Human Diseases; Cardiovascular diseases; Viral myocarditis [PATH:pon05416]
Human Diseases; Endocrine and metabolic diseases; Type I diabetes mellitus [PATH:pon04940]

SSDB

Motif

Pfam:

MACPF C2

Other DBs

NCBI-GI:

NCBI-GeneID:

Ensembl:

UniProt:

Position

AA seq 555 aa
MAARLLLLGIVLLLLPLPIPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFP
VDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARD
AARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYS
FHVVHTPPLHPDFKRALGDLPHHFNSSTQPAYLRLISNYGTHFIRAVELGGRISALTALR
TCELALEGLTDDEVEDCLTVEAQVNIGARGSSSAEAKACEEKKKKHKMTASFHQTYRERH
SEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREAL
RRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVT
FIQAWGLWGDWFTATDAYVKVFFGGQELRTSTVWSNNNPIWSVRLDFGDVLLATGGPLRL
QVWDQDSGWDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQ
MLLGEPPGNRSGAVW

NT seq 1668 nt +upstreamnt +downstreamnt
atggcagcccgtctgctcctcctgggcatcgttctcctgctgctgcccctgcccatccct
gccccgtgccacacggccgcacgctcagagtgcaagcgcagccacaagttcgtgcctggt
gcatggctggccggggagggtgtggatgtgaccagcctccgccgctcgggctccttccca
gtggacacacaaaggttcctgcggcccgacggcacctgcaccctctgtgaaaatgcccta
caggagggcaccctccagcgcctgcctctggcactcaccaactggcgggcccagggctct
ggctgccagcgccatgtaaccagggccaaagtcagctccactgaagctgtggcccgggat
gcggctcgtagcatccgcaacgactggaaggtcgggctggatgtgactcctaagcccacc
agcaatgtgcatgtgtccgtggctggctcacactcacaggcagccaactttgcagcccag
aagacccaccaggaccagtacagcttcagcactgacacagtggagtgccgcttctatagt
ttccatgtggtacacactcccccgctacaccctgacttcaagagggccctcggggacctg
ccccaccacttcaactcctccacccagcccgcctacctcaggctcatctccaactacggc
acccacttcatccgggctgtggagctgggcggccgtatctcggccctcactgccctgcgc
acctgcgagctggccctggaagggctcacggacgacgaggtggaggactgcctgaccgtc
gaggcccaggtcaacataggtgcccgcggcagctcctctgccgaagccaaggcctgtgag
gagaagaagaagaagcacaagatgacggcctccttccaccaaacctaccgggagcgccat
tcggaagtggttggcggccatcacacttccattaacgacctgctgttcgggatccaggcc
gggcccgagcagtactcagcctgggtgaactcgctgcccggcagccctggcctggtggac
tacaccctggaacccctgcacgtgctgctggacagccaggacccgcggcgggaggcactg
aggagggccctgagtcagtacctgacggacagggctcgctggagggactgcagccggccg
tgcccgccggggcggcagaagagcccccgagacccgtgccagtgtgtgtgccatggctca
gcggtcaccacccaggactgctgccctcggcagaggggcctggcccagctggaggtgacc
ttcatccaagcatggggcctgtggggggactggttcactgccactgatgcctatgtgaag
gtgttctttggtggccaggagctgaggacgagcaccgtgtggagcaataacaaccccatc
tggtcagtgcggctggattttggggatgtgctcctggccacaggggggcccctgaggttg
caggtctgggatcaggactctggctgggatgatgacctccttggcacctgtgatcaggct
cccaagtctggttcccatgaggtgagatgcaacctgaatcatggccacctaaaattccgc
tatcatgccaggtgcttgccccacctgggaggaggcacctgcctggactacgtcccccaa
atgcttctgggggagcctccaggaaaccggagtggggctgtgtggtga

All links

Pathway (6)   
   KEGG PATHWAY (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   ENSEMBL-PON (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (17)   

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