KEGG   Pongo abelii (Sumatran orangutan): 100452870Help
Entry
100452870         CDS       T01416                                 

Gene name
PRF1
Definition
perforin 1 (pore forming protein)
Orthology
K07818  
perforin 1
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
Natural killer cell mediated cytotoxicity
Type I diabetes mellitus
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:pon00001]
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100452870 (PRF1)
 Human Diseases
  Immune diseases
   05320 Autoimmune thyroid disease
    100452870 (PRF1)
   05330 Allograft rejection
    100452870 (PRF1)
   05332 Graft-versus-host disease
    100452870 (PRF1)
  Cardiovascular diseases
   05416 Viral myocarditis
    100452870 (PRF1)
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    100452870 (PRF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
10
AA seq 555 aa AA seqDB search
MAARLLLLGIVLLLLPLPIPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFP
VDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARD
AARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYS
FHVVHTPPLHPDFKRALGDLPHHFNSSTQPAYLRLISNYGTHFIRAVELGGRISALTALR
TCELALEGLTDDEVEDCLTVEAQVNIGARGSSSAEAKACEEKKKKHKMTASFHQTYRERH
SEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREAL
RRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVT
FIQAWGLWGDWFTATDAYVKVFFGGQELRTSTVWSNNNPIWSVRLDFGDVLLATGGPLRL
QVWDQDSGWDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQ
MLLGEPPGNRSGAVW
NT seq 1668 nt NT seq  +upstreamnt  +downstreamnt
atggcagcccgtctgctcctcctgggcatcgttctcctgctgctgcccctgcccatccct
gccccgtgccacacggccgcacgctcagagtgcaagcgcagccacaagttcgtgcctggt
gcatggctggccggggagggtgtggatgtgaccagcctccgccgctcgggctccttccca
gtggacacacaaaggttcctgcggcccgacggcacctgcaccctctgtgaaaatgcccta
caggagggcaccctccagcgcctgcctctggcactcaccaactggcgggcccagggctct
ggctgccagcgccatgtaaccagggccaaagtcagctccactgaagctgtggcccgggat
gcggctcgtagcatccgcaacgactggaaggtcgggctggatgtgactcctaagcccacc
agcaatgtgcatgtgtccgtggctggctcacactcacaggcagccaactttgcagcccag
aagacccaccaggaccagtacagcttcagcactgacacagtggagtgccgcttctatagt
ttccatgtggtacacactcccccgctacaccctgacttcaagagggccctcggggacctg
ccccaccacttcaactcctccacccagcccgcctacctcaggctcatctccaactacggc
acccacttcatccgggctgtggagctgggcggccgtatctcggccctcactgccctgcgc
acctgcgagctggccctggaagggctcacggacgacgaggtggaggactgcctgaccgtc
gaggcccaggtcaacataggtgcccgcggcagctcctctgccgaagccaaggcctgtgag
gagaagaagaagaagcacaagatgacggcctccttccaccaaacctaccgggagcgccat
tcggaagtggttggcggccatcacacttccattaacgacctgctgttcgggatccaggcc
gggcccgagcagtactcagcctgggtgaactcgctgcccggcagccctggcctggtggac
tacaccctggaacccctgcacgtgctgctggacagccaggacccgcggcgggaggcactg
aggagggccctgagtcagtacctgacggacagggctcgctggagggactgcagccggccg
tgcccgccggggcggcagaagagcccccgagacccgtgccagtgtgtgtgccatggctca
gcggtcaccacccaggactgctgccctcggcagaggggcctggcccagctggaggtgacc
ttcatccaagcatggggcctgtggggggactggttcactgccactgatgcctatgtgaag
gtgttctttggtggccaggagctgaggacgagcaccgtgtggagcaataacaaccccatc
tggtcagtgcggctggattttggggatgtgctcctggccacaggggggcccctgaggttg
caggtctgggatcaggactctggctgggatgatgacctccttggcacctgtgatcaggct
cccaagtctggttcccatgaggtgagatgcaacctgaatcatggccacctaaaattccgc
tatcatgccaggtgcttgccccacctgggaggaggcacctgcctggactacgtcccccaa
atgcttctgggggagcctccaggaaaccggagtggggctgtgtggtga

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