KEGG   Pongo abelii (Sumatran orangutan): 100453085Help
Entry
100453085         CDS       T01416                                 

Gene name
PIK3CG
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100453085 (PIK3CG)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100453085 (PIK3CG)
   04015 Rap1 signaling pathway
    100453085 (PIK3CG)
   04012 ErbB signaling pathway
    100453085 (PIK3CG)
   04370 VEGF signaling pathway
    100453085 (PIK3CG)
   04630 Jak-STAT signaling pathway
    100453085 (PIK3CG)
   04668 TNF signaling pathway
    100453085 (PIK3CG)
   04066 HIF-1 signaling pathway
    100453085 (PIK3CG)
   04068 FoxO signaling pathway
    100453085 (PIK3CG)
   04070 Phosphatidylinositol signaling system
    100453085 (PIK3CG)
   04024 cAMP signaling pathway
    100453085 (PIK3CG)
   04022 cGMP - PKG signaling pathway
    100453085 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    100453085 (PIK3CG)
   04152 AMPK signaling pathway
    100453085 (PIK3CG)
   04150 mTOR signaling pathway
    100453085 (PIK3CG)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100453085 (PIK3CG)
  Cell growth and death
   04210 Apoptosis
    100453085 (PIK3CG)
  Cellular commiunity
   04510 Focal adhesion
    100453085 (PIK3CG)
   04550 Signaling pathways regulating pluripotency of stem cells
    100453085 (PIK3CG)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100453085 (PIK3CG)
   04620 Toll-like receptor signaling pathway
    100453085 (PIK3CG)
   04650 Natural killer cell mediated cytotoxicity
    100453085 (PIK3CG)
   04660 T cell receptor signaling pathway
    100453085 (PIK3CG)
   04662 B cell receptor signaling pathway
    100453085 (PIK3CG)
   04664 Fc epsilon RI signaling pathway
    100453085 (PIK3CG)
   04666 Fc gamma R-mediated phagocytosis
    100453085 (PIK3CG)
   04670 Leukocyte transendothelial migration
    100453085 (PIK3CG)
   04062 Chemokine signaling pathway
    100453085 (PIK3CG)
  Endocrine system
   04910 Insulin signaling pathway
    100453085 (PIK3CG)
   04915 Estrogen signaling pathway
    100453085 (PIK3CG)
   04914 Progesterone-mediated oocyte maturation
    100453085 (PIK3CG)
   04917 Prolactin signaling pathway
    100453085 (PIK3CG)
   04921 Oxytocin signaling pathway
    100453085 (PIK3CG)
   04919 Thyroid hormone signaling pathway
    100453085 (PIK3CG)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100453085 (PIK3CG)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100453085 (PIK3CG)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100453085 (PIK3CG)
  Nervous system
   04725 Cholinergic synapse
    100453085 (PIK3CG)
   04722 Neurotrophin signaling pathway
    100453085 (PIK3CG)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100453085 (PIK3CG)
  Development
   04380 Osteoclast differentiation
    100453085 (PIK3CG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100453085 (PIK3CG)
   05205 Proteoglycans in cancer
    100453085 (PIK3CG)
   05203 Viral carcinogenesis
    100453085 (PIK3CG)
   05210 Colorectal cancer
    100453085 (PIK3CG)
   05212 Pancreatic cancer
    100453085 (PIK3CG)
   05214 Glioma
    100453085 (PIK3CG)
   05221 Acute myeloid leukemia
    100453085 (PIK3CG)
   05220 Chronic myeloid leukemia
    100453085 (PIK3CG)
   05218 Melanoma
    100453085 (PIK3CG)
   05211 Renal cell carcinoma
    100453085 (PIK3CG)
   05215 Prostate cancer
    100453085 (PIK3CG)
   05213 Endometrial cancer
    100453085 (PIK3CG)
   05222 Small cell lung cancer
    100453085 (PIK3CG)
   05223 Non-small cell lung cancer
    100453085 (PIK3CG)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100453085 (PIK3CG)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100453085 (PIK3CG)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100453085 (PIK3CG)
   05166 HTLV-I infection
    100453085 (PIK3CG)
   05162 Measles
    100453085 (PIK3CG)
   05164 Influenza A
    100453085 (PIK3CG)
   05161 Hepatitis B
    100453085 (PIK3CG)
   05160 Hepatitis C
    100453085 (PIK3CG)
   05169 Epstein-Barr virus infection
    100453085 (PIK3CG)
   05146 Amoebiasis
    100453085 (PIK3CG)
   05145 Toxoplasmosis
    100453085 (PIK3CG)
   05142 Chagas disease (American trypanosomiasis)
    100453085 (PIK3CG)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100453085 (PIK3CG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
7
AA seq 1102 aa AA seqDB search
MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPKLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGEAPIKNFQWVRHCLKNG
EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKSEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
NT seq 3309 nt NT seq  +upstreamnt  +downstreamnt
atggagctggaaaactataaacagcccgtggtgctgagagaggacaactgccgcaggcgc
cggaggatgaagccgcgcagtgctgcagccagcctgtcctccatggagctcatccccatc
gagttcgtgctgcccaccagccagcgcaaatgcaagagccccgaaacggcgctgctgcac
gtggcgggccacggcaacgtggagcagatgaaggcccaggtgtggctgcgagctctggag
accagcgtggcagcggacttctaccaccggctgggccctgaccacttcctcctgctctat
cagaagaaggggcagtggtacgagatctacgacaagtaccaggtggtgcagactctggac
tgcctgcgctactggaaggccacacaccggagcccgggccagatccacctggtgcagcgg
cgcccgccctccgaagagtcgcaagccttccagcggcagctcaccgcgctgattggctat
gacgtcactgacgtcagcaacgtgcacgacgacgagctggagttcacgcgccgtggcttg
gtgaccccgcgcatggcggaggtggccagccgcgaccccaagctctacgccatgcacccg
tgggtgacgtccaagcccctcccggagtacctgtggaagaagattgccaacaactgcatc
ttcatcgtcattcaccgcagcaccaccagccagaccattaaggtctcgcccgacgacacc
cccggcaccatcctgcagagcttcttcaccaagatggccaagaagaaatctctgatggat
attcccgaaagccaaagcgaacaggattttgtgctgcgcgtctgtggccgggatgagtac
ctggtgggcgaagcgcccatcaaaaacttccagtgggtgaggcactgcctcaagaacggg
gaagagattcacgtggtactggacacgcctccagacccggccctagacgaggtgaggaag
gaagagtggccgctggtggacgactgcacgggagtcaccggctaccatgagcagcttacc
atccacggcaaggaccacgagagtgtgttcaccgtgtccctgtgggactgcgaccgcaag
ttcagagtcaagatcagaggcattgatatccccgtcctgccccggaacaccgacctcaca
gtttttgtagaggcaaacatccagcatgggcaacaagtcctttgccaaaggagaaccagc
cccaaacccttcacagaggaggtgctgtggaatgtgtggcttgagttcagtatcaaaatc
aaagacttgcccaaaggggctctactgaacctccagatctactgcggtaaagctccagca
ctgtccagcaaggcctctgcagagtcccccagttctgagtccaagggcaaagttcaactt
ctctattatgtgaacctgctgctgatagaccaccgtttcctcctgcgccgtggagaatac
gtcctccacatgtggcagatatccgggaagggagaagaccaaggaagcttcagtgctgac
aaactcacgtctgcaactaacccagacaaggagaactcaatgtccatctccattcttctg
gacaattactgccacccgatagccctgcctaagcatcagcccacccctgacccggaaggg
gaccgggttcgagcagaaatgcccaaccagcttcgcaagcaattggaggcgatcatagcc
actgatccacttaaccctctcacagcagaggacaaagaattgctctggcattttagatat
gaaagccttaagcacccaaaagcatatcctaagctatttagttcagtgaaatggggacag
caagaaattgtggccaaaacataccaattgttggccagaagggaagtctgggatcaaagt
gctttggatgttgggttaacaatgcaactcctggactgcaacttctcagatgaaaatgta
agagccattgcagttcagaaactggagagcttggaggacgatgatgttctgcattacctt
ctacaattggtccaggctgtgaaatctgaaccataccatgatagcgcccttgccagattt
ctgctgaagcgtggtttaagaaacaaaagaattggtcactttttgttttggttcttgaga
agtgagatagcccagtccagacactatcagcagaggttcgctgtgattctggaagcctat
ttgaggggctgtggcacagccatgctgcacgactttacccaacaagtccaagtaatcgag
atgttacaaaaagtcacccttgatattaaatcgctctctgctgaaaagtatgacgtcagt
tcccaagttatttcacaacttaaacaaaagcttgaaaacctgcagaattctcaactcccc
aaaagctttagagttccatatgatcctggactgaaagcaggagcgctggcaattgaaaaa
tgtaaagtaatggcctccaagaaaaaaccactgtggcttgagtttaaatgtgctgatcct
acagccctatcaaatgaaacaattggaattatctttaaacacggtgatgatctgcgccaa
gacatgcttattttacagattctacgaatcatggagtctatttgggagactgaatctttg
gatctgtgcctcctgccatatggttgcatttcaactggtgacaaaataggaatgatcgag
attgtgaaagacgccacgacaatcgccaaaatccagcaaagcacagtgggcaacacggga
gcatttaaagatgaagtcctgaatcactggctcaaagaaaaatcccctactgaagaaaag
tttcaggcagcagtggagagatttgtttattcctgtgcaggctactgtgtggcaaccttt
gttcttggaataggcgacagacacaatgacaatattatgatcaccgagacaggaaaccta
tttcatattgacttcgggcacattcttgggaattacaaaagtttcctgggcattaataaa
gagagagtgccatttgtgctaacccctgacttcctctttgtgatgggaacttctggaaag
aagacaagcccacacttccagaaatttcaggacatctgtgtcaaggcttatctagccctt
cgtcatcacacaaacctactgatcatcctgttctccatgatgctgatgacgggaatgcct
cagttaacaagcaaagaagacattgaatatatccgggatgccctcacagtggggaaaaat
gaggaggatgctaaaaagtattttcttgatcagattgaagtttgcagagacaaaggatgg
actgtgcagtttaattggtttctacatcttgttcttggcatcaaacaaggagagaaacat
tcagcctaa

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